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Pediatr Rev 2018 Dec;39(12):617-619

Division of Pediatric Hematology and Oncology, Department of Pediatrics.

Sex Med Rev 2018 Nov 28. Epub 2018 Nov 28.

Department of Urology, Tulane University, New Orleans, LA, USA. Electronic address:

Background: Priapism has been linked to many commonly prescribed medications, as well as recreational drugs and toxins. Although the incidence of priapism as a result of medication is small, the increasing use of antidepressants, antipsychotics, and recreational drugs may lead to more cases of pharmacologically-induced priapism in the future.

Aim: To provide a comprehensive, up-to-date review of the most common causes of pharmacologically induced priapism and discuss incidence, pathophysiology, and basic management strategies. Read More

Rev Int Androl 2018 Nov 27. Epub 2018 Nov 27.

Radiology Department, Hospital Clínico Universitario de Santiago de Compostela, Spain.

Partial thrombosis of corpus cavernosum is an uncommon condition that needs a high level of suspicious to be diagnosed. Imaging techniques may be very useful, and MR is the state-of-the-art technique. We present a case of a young male who presented to the emergency department with perineal and painful mass. Read More

Int Urol Nephrol 2018 Dec 4. Epub 2018 Dec 4.

Department of Urology, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey.

Purpose: This study aimed to demonstrate the effects of oxytocin on penile tissues in ischemia-reperfusion injury developed after priapism.

Methods: Forty Wistar Albino strain male rats were divided into four groups. The control group (n = 10) was not intervened. Read More

J Cancer Res Ther 2018 Oct-Dec;14(6):1442-1443

Department of Hematology, SGPGI, Lucknow, Uttar Pradesh, India.

Urology 2018 Nov 21. Epub 2018 Nov 21.

Cleveland Clinic Foundation, Glickman Urological & Kidney Institute.

J Urol 2018 Sep 1;200(3):490-492. Epub 2018 Jun 1.

Cir Pediatr 2018 Oct 17;31(4):200-203. Epub 2018 Oct 17.

Servicio de Cirugía Pediátrica. Hospital Universitario Central de Asturias. Oviedo.

Introduction: High-flow priapism is infrequent in pediatric patients. It is mostly secondary to perineal trauma resulting in laceration of a penile artery and the formation of an arterio-cavernous fistula. It does not constitute a medical emergency in itself, and allows conservative management awaiting spontaneous resolution. Read More

Arch Ital Urol Androl 2018 Sep 30;90(3):218-219. Epub 2018 Sep 30.

Department of Urology, University of Trieste, Cattinara Hospital, Trieste.

Introduction: High-flow priapism is a rare condition in children, usually due to a perineal trauma.

Materials And Methods: We present a case of traumatic highflow priapism investigated by Doppler ultrasound and managed by angiography and selective embolization of a branch of the internal pudendal artery.

Results: A 13-year-old gymnast underwent perineal trauma during training and developed a high-flow priapism. Read More

Curr Drug Saf 2018 Oct 25. Epub 2018 Oct 25.

Dept. of Pharmacy Practice, Faculty of Pharmacy, M S Ramaiah University of Applied Sciences, Bengaluru. India.

Background: The signal is defined as "reported information on a possible causal relationship between an adverse event and a drug, of which the relationship is unknown or incompletely documented previously".

Objective: To detect novel adverse events of iloperidone by disproportionality analysis in FDA database of Adverse Event Reporting System [FAERS] using Data Mining Algorithms (DMAs).

Methodology: The USFDA AERS database is consist of 1028 Drug Event Combinations (DECs) were associated with iloperidone which were reported from 2010 Q1 to 2016 Q3. Read More

Indian J Urol 2018 Oct-Dec;34(4):283-286

Department of Urology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Introduction: We aim to present a modified technique and outcomes of a novel method allowing for direct visualization of the reservoir placement during a penoscrotal inflatable penile prosthesis (IPP).

Methods: Out of165 patients who underwent IPP placement from August 2012 to March 2015, 157 underwent a modified technique and comprised the cohort of this study. A Deaver's retractor was placed lateral to the penis and over the pubic bone to allow for direct visualization of the tissues overlying the lower abdomen. Read More

Eur Urol Focus 2018 04 14;4(3):338-347. Epub 2018 Oct 14.

Division of Male Reproductive Surgery and Men's Health, Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address:

Imaging can benefit clinicians in evaluating men with infertility or sexual dysfunction by giving an overview of a patient's overall clinical condition before undertaking an invasive procedure. An understanding of the limitations and advantages of image modalities used in clinical practice will ensure that clinicians can optimize patient care with imaging when necessary. PATIENT SUMMARY: The objective of this article was to review the current literature on imaging modalities used for the diagnosis and management of male infertility and sexual dysfunction. Read More

J Pak Med Assoc 2018 Jun;68(6):942-944

Rehman Medical Institute.

Priapism is known as a very rare complication of leukaemia. We report a 16-years boy who presented with the persistent painful erection of the penis for eleven days. He had aspiration without achieving sustained detumescence. Read More

Rev Bras Enferm 2018 Sep-Oct;71(5):2418-2424

Universidade Federal da Bahia, School of Nursing. Salvador, Bahia, Brazil.

Objective: To identify self-care demands of men with sickle cell disease and priapism and describe self-care measures in light of Orem's Self-Care Theory.

Method: This is a descriptive exploratory study with qualitative approach conducted with nine men with a history of sickle cell disease and priapism. Data were analyzed using Orem's Self-Care Theory. Read More

Drug Des Devel Ther 2018 12;12:2923-2931. Epub 2018 Sep 12.

Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Szeged, Hungary,

Purpose: Papaverine hydrochloride (PaHCl) is an old, well-known drug with spasmolytic activity but it has therapeutic effect in erectile dysfunction, too. As an intracavernous injection, it is not used in urologic clinics today because the side effects of the injection are pain, scarring or priapism. Our aim was to develop and test a topical semi-solid preparation containing PaHCl that would provide an alternative administration option by eliminating the undesirable side effects of the injection. Read More

Vasc Health Risk Manag 2018 6;14:199-204. Epub 2018 Sep 6.

Comprehensive Sickle Cell Program Children's National Medical Center, Division of Hematology, School of Medicine and Health Sciences George Washington University, Washington, DC, USA.

Background: Nitric oxide (NO) plays a fundamental role in maintaining normal vasomotor tone. Recent clinical and experimental data suggest that NO may play a role in the pathogenesis and therapy of sickle cell disease (SCD). The aim of this study was to determine NO metabolites (NOx) in SCD patients at steady state and in vaso-occlusive crisis (VOC), as well as those with hemolytic clinical sub-phenotype that includes leg ulcers and priapism. Read More

World J Biol Psychiatry 2018 Sep 13:1-17. Epub 2018 Sep 13.

a University Clinic for Psychiatry and Psychotherapy, Brandenburg Medical School , Immanuel Klinik Rüdersdorf , 15662 Rüdersdorf , Germany.

Priapism is a rare adverse effect of several psychotropics. Both, typical and atypical antipsychotics, as well as trazodone are known to cause priapism. The mechanism is still not fully understood, however, the most common assumption is that priapism occurs due to the α-adrenergic blocking effects of the drugs. Read More

Radiol Bras 2018 Jul-Aug;51(4):257-261

MD, Urologist, Member of the Clinical Staff of the Urology Department of the Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, MG, Brazil.

Ultrasound is an excellent method for the study of penis. In this article, using a critical review of the literature and teaching files, we present examples of the major findings in the ultrasound routine, focusing on trauma, priapism, Peyronie's disease, and erectile dysfunction. Read More

Prog Urol 2018 Sep 7. Epub 2018 Sep 7.

Department of Urology, Pitié Salpétrière Hospital, Sorbonne Université, 47-83 boulevard de l'Hôpital, 75013 Paris, France. Electronic address:

Objective: Our aim was to present a synthesis on the diagnosis and treatment of priapism.

Methods: For this purpose, a literature search was performed through PubMed to analyze literature reviews and guidelines regarding priapism.

Results: Priapism is an erection that persists more than 4hours. Read More

Zhonghua Nan Ke Xue 2018 Aug;24(8):675-680

Department of Urology, Donghua Hospital Affiliated to Sun Yat-sen University, Dongguan, Guangdong 523120, China.

Priapism is a rare pathological penile erection, and there are some inadequacies in its definition, classification, diagnosis, and therapeutic strategies. In this article, we sum up our years of experience with priapism and put forward some new views and ideas about its definition, classification, pathophysiologic process, pathological change, diagnostic essentials, therapeutic measures, indications of successful treatment, and post-therapeutic rehabilitation of erectile function. We also describe the clinical features, diagnosis and treatment of some special types of priapism, such as intermittent seizure, sleep-related painful erection, and tumor-related priapism, hoping to help urologists and andrologists in the further understanding and management of priapism. Read More

Zhonghua Nan Ke Xue 2018 Janurary;24(1):59-61

Department of Urology, The 9th People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.

Objective: To introduce our experience in the treatment of arterial priapism by superselective embolization.

Methods: This study included 5 cases of perineal trauma-induced arterial erectile dysfunction treated in our departmentbetween February 2011 and May 2015, all failingpreviously to respond to 3 weeks of conservative treatment. The patients were aged 25－47 (mean 35) years, with the onset of arterial priapism at 2－5 days after trauma, and all subjected to physical examination, blood gas analysis, color Doppler ultrasonography of the corpora cavernosum, and IIEF-5 scoring. Read More

Zhonghua Nan Ke Xue 2018 Feb;24(2):163-167

Department of Ultrasonic Medicine, The 10th People's Hospital of Tongji University, Shanghai 200072, China.

Penile disease is one of the male urological diseases. Although the penis is a small organ, once the problem occurs, it often brings great trouble to the patient. Therefore, the accurate diagnosis of penile disease is particularly important. Read More

Int Braz J Urol 2018 Sep-Oct;44(5):1023-1031

Department of Urology, Harran University Medical School, Sanliurfa, Turkey.

Objective: To protect the urethra from instrumentation related urethra injures and stricture, we developed a new surgical technique which can be defined as transvesical resection of prostate without using urethra.

Materials And Methods: Our study included 12 consecutive bladder outlet obstruction patients treated with transvesical prostate resection in our clinic between March 2016 and May 2016. Detailed anamnesis, results of physical examination, digital rectal examination, routine lab tests, international prostate symptoms score, transrectal ultrasound, measurement of prostate-specific antigen levels and uroflowmetry was performed in all patients prior to surgery. Read More

BMJ Case Rep 2018 Aug 14;2018. Epub 2018 Aug 14.

Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Cureus 2018 Jun 7;10(6):e2758. Epub 2018 Jun 7.

Graduate Medical Education, Florida Hospital-Orlando, Orlando, USA.

Priapism, a persistent erection of the penis which has no association with sexual activity and lasts longer than four hours, is a urologic emergency. It can be classified into ischemic, nonischemic, and stuttering categories. The pathophysiology of stuttering priapism is not well understood; however, the dysregulation of nitric oxide and phosophodiesterase-5 (PDE5) has been put forward as a possible mechanism. Read More

Curr Med Sci 2018 Feb 15;38(1):101-106. Epub 2018 Mar 15.

Department of Infertility and Sexual Medicine, Guangzhou, 510630, China.

This study is aimed to evaluate the effectiveness and safety of the treatment of highflow priapism with superselective transcatheter embolization. From Sep. 1999 to Jan. Read More

Urology 2018 Jul 29. Epub 2018 Jul 29.

Department of Radiology, Division of Vascular and Interventional Radiology, University of Michigan Health Systems, Ann Arbor, MI; Department of Interventional Radiology, University of California, 757 Westwood Plaza, Los Angeles, CA 90095.

Objective: To report long term outcomes of selective arterial embolization for nonischemic priapism on erectile function utilizing validated outcome questionnaires after selective arterial embolization.

Materials And Methods: Twenty men, mean age of 36years (range: 8-58 years), underwent selective penile embolization for nonischemic priapism between December 1997 and February 2016 (218 months). Each identified case of nonischemic priapism was embolized using gelatin sponge, autologous blood clot, platinum microcoils, polyvinyl alcohol particles, or a combination of these. Read More

Ital J Pediatr 2018 Jul 27;44(1):85. Epub 2018 Jul 27.

Department of Surgical Science, University of Cagliari and Neonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, Azienda Ospedaliera Universitaria, Cagliari, I-09042, Italy.

Neonatal priapism is a rare condition with only 26 described cases in literature since 1879. It is defined as a persistent penile erection occurring in the first 28 days of life, lasting at least 4 h that usually happens in the first days (from 2 to 12 days). It is a very different condition compared to the adult one because in newborns it is a relatively benign phenomenon. Read More

Ned Tijdschr Geneeskd 2018 Jun 15;162. Epub 2018 Jun 15.

UMCG-Rijksuniversiteit Groningen, afd. Urologie, Groningen.

The term priapism describes erections of >4 hours that arise in the absence of or last well beyond sexual stimulation. Ischaemic priapism is the most common form and treatment success is strongly dependent on the duration of priapism. The aetiology is widely variable as a result of which several specialisms can be confronted with this condition. Read More

Niger J Clin Pract 2018 Jul;21(7):882-887

Hematology and Hemotherapy Center, University of Campinas, São Paulo, Brazil.

Background: Sickle leg ulcer (SLU) is a chronic and debilitating complication of sickle cell disease (SCD) associated with huge physical and psychosocial discomfort. The occurrence of SLU has remained steady despite successful preventive strategies and advances in SCD care. Although multifactorial factors have been implicated in SLU, these are not fully understood, and data on how these relate to young Nigerian SCD patients are scanty. Read More

J Sex Med 2018 Jul;15(7):990-996

Columbia Urology Division of Urology at Mount Sinai Medical Center, Miami Beach, FL, USA.

Aim: We sought to evaluate whether the administration of phenylephrine (PE) at concentrations higher than those described in guidelines resulted in any significant changes in vital signs or impacted outcomes.

Methods: After receiving institutional review board approval, we retrospectively reviewed the charts of patients presenting to our emergency department between May 1, 2014, and August 15, 2016, using International Classification of Diseases, Ninth Edition and Internation Classification of Disease, Tenth Edition diagnosis codes for priapism. Treatment was reviewed, including corporal aspiration/irrigation, injection of PE, and shunt procedures. Read More

J Stomatol Oral Maxillofac Surg 2018 Dec 28;119(6):493-497. Epub 2018 Jun 28.

Department of maxillofacial and plastic surgery, Caen university hospital, 14000 Caen, France; Medicine faculty of Caen, university of Caen Basse Normandie, 14032 Caen cedex 5, France; UNICAEN, EA7451 Équipe BioConnecT, avenue de la Côte-de-Nacre, 14000 Caen, France.

Sickle cell disease, the most common genetic disease in the world, is a chronic hemolytic disease that can be complicated by severe vaso-occlusive pain crises resulting in tissue necrosis and even death. Due to its increasing incidence, oral surgeons will inevitably be faced with the management of these patients. To limit the risk of crises, our goal is to share recommendations for the management of sickle cell patients in oral surgery. Read More

Unfallchirurg 2018 Aug;121(8):674-676

Rechtsanwalt und Fachanwalt für Medizinrecht, Kanzlei Dres. Vogeler Rechtsanwälte, Brehmstraße 1, 30173, Hannover, Deutschland.

There are no pharmaceuticals without side effects. Primary care physicians and especially hospital staff have to ask themselves every time they are administering medication whether they should inform the patient about possible risks and alternative treatment options. The "bizarre" side effects which can occur even from taking routine medication are illustrated by a legal case decided by the District Court of Hannover: After surgery a patient developed an anticoagulant-induced priapism. Read More

J Pediatr Urol 2018 Oct 7;14(5):465-466. Epub 2018 Jun 7.

Medical University of South Carolina, Department of Urology, Pediatric Urology, Charleston, SC, USA.

Clin Toxicol (Phila) 2018 Jun 22:1-4. Epub 2018 Jun 22.

b Georgia Poison Center , Atlanta , GA , USA.

Context: Trazodone is an atypical antidepressant with no established safety in children. Previous case reports showed no complications at doses 50-500 mg in children. Our study objective is to characterize the clinical effects, dose-related toxicity, and establish triage dose for acute trazodone ingestions in children ≤6 years of age. Read More

Gynecol Oncol Rep 2018 May 1;24:99-101. Epub 2018 May 1.

St. Thomas Midtown Hospital, 2004 Hayes Street, Suite 205, Nashville, TN 37203, United States.

•Cutaneous metastasis at the initial presentation of ovarian carcinoma is rare.•Clitoral metastasis in a gynecological malignancy can occasionally present as clitoral priapism.•Clitoral priapism can be treated with oral or intramuscular alpha blockade. Read More

Int J Impot Res 2018 Aug 19;30(4):190-191. Epub 2018 Jun 19.

Department of Urology, Stanford University School of Medicine, Stanford, CA, USA.

Male enhancement and erectile dysfunction supplements are typically non-Food and Drug Administration (FDA) approved and readily available for purchase by anyone. Longstanding priapism is a significant potential side effect. A 25-year-old man presented with a 48-h priapism after taking Rhino 7 Platinum 3000. Read More

Urol Case Rep 2018 Jul 12;19:48-49. Epub 2018 May 12.

Department of Urology, Hospital Santa Marcelina, Brazil.

Urol Case Rep 2018 Jul 31;19:1-3. Epub 2018 Mar 31.

Genitourinary Oncology Service, Sidney Kimmel Center for Prostate and Urologic Cancers, Memorial Sloan Kettering Cancer Center, New York, United States.

Am J Hematol 2018 Jun 8. Epub 2018 Jun 8.

Internal medicine department, Sickle Cell Referral Center, Georges Pompidou European Hospital, AP-HP, Paris, France.

J Fam Pract 2018 Jun;67(6):E10-E11

University of Louisiana Lafayette US Army Reserves, USA.

A 35-year-old African-American man, who was an active duty service member, presented to the Troop Medical Clinic with a 4-hour history of priapism. He had been taking sertraline 100 mg and prazosin 10 mg nightly for 4 months to treat his posttraumatic stress disorder (PTSD) with no reported adverse effects. These doses were titrated 2 months prior to presentation. Read More

BMC Urol 2018 May 31;18(1):54. Epub 2018 May 31.

Department of Urology and Renal Transplantation, University of Foggia, Foggia, Italy.

Background: Recurrent (stuttering) ischemic priapism is a challenging clinical condition. Frequent recurrences result in frequent hospital admissions whereas treatment with a shunting procedure often results in erectile dysfunction.

Case Presentation: A 22-year-old man with stuttering idiopathic priapism developed erectile dysfunction (IIEF-5 score 12) following a Winter's shunt; he was given tadalafil, 5 mg/daily, for 6 months. Read More

J Pediatr Urol 2018 Oct 16;14(5):467. Epub 2018 May 16.

University of North Carolina, Chapel Hill, NC, USA. Electronic address:

Med Gas Res 2018 Jan-Mar;8(1):29-33. Epub 2018 Apr 18.

Department of Physiology and Biophysics, Stony Brook University School of Medicine, Stony Brook, NY, USA.

Hyperbaric oxygen therapy (HBOT) is a medical technique which delivers oxygen at ambient pressures to increase the amount of dissolved oxygen in the blood and oxygen distribution to tissues. There are several beneficial properties of HBOT concomitant with elevated oxygen distribution in tissue including anti-inflammation, angiogenesis through vascular endothelial growth factor proliferation, augmented fibroblast activity through fibroblast growth factor proliferation, tissue and wound repair, enhancement of lymphocyte and macrophage activity, increased male testosterone secretion, and bactericidal activity. Given its renown in treating conditions such as decompression sickness and carbon monoxide poisoning, HBOT is making gradual strides for use in genitourinary medicine due to its low risk and likeliness to achieve favorable results. Read More

Hemoglobin 2018 Mar 10;42(2):73-77. Epub 2018 May 10.

b Professora Associada da Disciplina de Genética da UFTM , Uberaba , Minas Gerais , Brasil.

Priapism is a pathological condition of persistent penile erection in the absence of sexual arousal or desire. It is an urological emergency and its identification is important as lack of prompt treatment can result in erectile dysfunction. The aim of this study was to estimate and describe the characteristics (number of episodes, duration, time of occurrence and evolution) of priapism in patients with sickle cell disease. Read More

Oncotarget 2018 Apr 13;9(28):20156-20164. Epub 2018 Apr 13.

The Andrology Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Lysyl oxidase (LOX) is an extracellular copper-dependent monoamine oxidase that catalyzes crosslinking of soluble collagen and elastin into insoluble, mature fibers. Lysyl oxidase-like proteins (LOXL), LOX isozymes with partial structural homology, exhibit similar catalytic activities. This review summarizes recent findings describing the roles of LOX family members in urological cancers and fibrosis. Read More

Urology 2018 Aug 2;118:21-24. Epub 2018 May 2.

Department of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.