1,094 results match your criteria Pretibial Myxedema


A case of right ventricular diastolic dysfunction due to a large hematoma posterior to the left ventricle.

J Cardiol Cases 2015 Jul 21;12(1):8-11. Epub 2015 Mar 21.

Tokyo Bay Urayasu Ichikawa Medical Center, Cardiovascular Medicine, Urayasu, Japan.

We report a case of right ventricular (RV) diastolic dysfunction due to a large hematoma posterior to the left ventricle (LV) after cardiac surgery. An 80-year-old woman underwent cardiac surgery. After surgery, her physical findings revealed right heart failure. Read More

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Intralesional and topical glucocorticoids for pretibial myxedema: A case report and review of literature.

World J Clin Cases 2018 Nov;6(14):854-861

Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.

Pretibial myxedema (PTM), an uncommon manifestation of Graves' disease (GD), is a local autoimmune reaction in the cutaneous tissue. The treatment of PTM is a clinical challenge. We herein report on a patient with PTM who achieved complete remission by multipoint subcutaneous injections of a long-acting glucocorticoid and topical glucocorticoid ointment application for a self-controlled study. Read More

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November 2018
3 Reads

The "Rule of 10s" versus the "Rule of 2s": High complication rates after conventional excision with postoperative margin assessment of specialty site versus trunk and proximal extremity melanomas.

J Am Acad Dermatol 2018 Nov 14. Epub 2018 Nov 14.

Department of Dermatology, University of Pennsylvania Health System. Philadelphia, Pennsylvania. Electronic address:

Specialty site melanomas on the head and neck, hands and feet, genitalia, and pretibial leg have higher rates of surgical complications after conventional excision with postoperative margin assessment (CE-POMA) compared to trunk and proximal extremity (T&PE) melanomas. The "rule of 10s" describes complication rates after CE-POMA of specialty site melanomas: ∼10% risk of upstaging, ∼10% risk of positive excision margins, ∼10% risk of local recurrence, and ∼10-fold increased likelihood of reconstruction with a flap or graft. T&PE melanomas encounter these complications at a lower rate, according to the "rule of 2s. Read More

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November 2018
3 Reads

Autoimmune Progesterone Dermatitis Diagnosed by Lymphocyte Transformation Test and Progesterone Provocation Test.

Acta Dermatovenerol Croat 2018 Oct;26(3):276-277

Assoc. Prof. Suzana Ljubojević Hadžavdić, MD, PhD, Department of Dermatology and Venereology University Hospital Center Zagreb School of Medicine University of Zagreb, Šalata 4, 10000 Zagreb, Croatia;

Autoimmune progesterone dermatitis (APD) is rare autoimmune response to endogenous progesterone or to earlier exposure to exogenous progesterone (1). Skin lesions typically occur due to increases in progesterone during the luteal phase of the menstrual cycle (2). A-31-year-old mother of two children presented to our Department with a 5-year history of pruritic and painful erythematosus macules, papules, and patches on her neck, pectoral region, and face, which appeared 2-3 days before the onset of menses and gradually resolved 7-10 days later (Figure 1). Read More

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October 2018
6 Reads

Pretibial myxedema.

Med Clin (Barc) 2018 Oct 15. Epub 2018 Oct 15.

Servicio de Dermatología, Hospital Regional Universitario de Málaga, Málaga, España.

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October 2018
1 Read

Pretibial myxedema successfully treated with intralesional hyaluronidase.

JAAD Case Rep 2018 Oct 3;4(9):874-876. Epub 2018 Oct 3.

Department of Dermatology, Mayo Clinic, Jacksonville, Florida.

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October 2018
4 Reads

Erythema nodosum.

World J Pediatr 2018 Dec 29;14(6):548-554. Epub 2018 Sep 29.

Department of Pediatrics and Department of Dermatology and Skin Sciences, University of British Columbia, Vancouver, BC, Canada.

Background: Erythema nodosum can be associated with a number of systemic diseases. There is, however, a paucity of information in the pediatric literature on this condition. The purpose of this article is to familiarize pediatricians with the evaluation, diagnosis, and treatment of erythema nodosum. Read More

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December 2018
8 Reads

[Review through a clinical case of pretibial injuries].

Aten Primaria 2018 Sep 20. Epub 2018 Sep 20.

Medicina Familiar y Comunitaria, Servicio de Urgencias, ICS-Atenció Primària Costa de Ponent, Hospital de Viladecans, Viladecans, Barcelona, España.

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September 2018

Pretibial Lymphoplasmacytic Plaque in Children: Case Report and Review of the Literature.

Am J Dermatopathol 2018 Aug 15. Epub 2018 Aug 15.

Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

An 8-year-old girl presented with a persistent 5 × 2-cm violaceous doughy plaque on the left lower leg. Histologic examination revealed hyperkeratosis, variable but mild epidermal hyperplasia, and vacuolar interface changes with melanin pigment incontinence confined to the papillary dermis. A diagnosis of pretibial lymphoplasmacytic plaque in children was made. Read More

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August 2018
1 Read

Treatment of adult Graves' disease.

Ann Endocrinol (Paris) 2018 Dec 16;79(6):618-635. Epub 2018 Aug 16.

Service de médecine nucléaire, Inserm U970, Sorbonne université, groupe hospitalier Pitié-Salpétrière, 75013 Paris, France.

Treatment strategy in Graves' disease firstly requires recovery of euthyroid status by antithyroid therapy. Treatment modalities, precautions, advantages and side-effects are to be discussed with the patient. No particular treatment modality has demonstrated superiority. Read More

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December 2018
2 Reads

Thyroid dermopathy and acropachy in pediatric patients.

Pediatr Dermatol 2018 Nov 6;35(6):e371-e374. Epub 2018 Sep 6.

George Washington University School of Medicine & Health Sciences, Washington, District of Columbia.

The extrathyroid manifestations of Graves disease (GD) include thyroid orbitopathy, dermopathy, and acropachy. Thyroid dermopathy (TD), also known as pretibial myxedema, classically presents as nonpitting edema or plaquelike lesions on the pretibial region, while thyroid acropachy (TA) is seen in cases of severe TD, characterized by soft tissue swelling and clubbing of fingers and toes, as well as a periosteal reaction of the bones of the hands and feet. Both TD and TA are rare manifestations of thyroid disease and uncommonly reported in pediatric patients. Read More

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November 2018
5 Reads

Influence of wheelchair user interface and personal characteristics on static and dynamic pretibial skin pressures in elite wheelchair racers, a pilot study.

J Spinal Cord Med 2018 Aug 21:1-9. Epub 2018 Aug 21.

a Department of Kinesiology and Community Health , College of Applied Health Sciences, University of Illinois at Urbana-Champaign , Illinois , USA.

Context/objective: To examine personal (athletic classification, age, sex, body mass index, duration of disability, tactile sensation of lower extremities) and wheelchair (kneeling plate angle) factors associated with increased pretibial skin pressures in elite wheelchair racers.

Design: Cross-sectional study.

Setting: University-based laboratory in Champaign, USA. Read More

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August 2018
2 Reads
1.880 Impact Factor

Bedside Echocardiography in Acute Myocardial Infarction Patients with Hemodynamic Deterioration.

J Natl Med Assoc 2018 Aug 18;110(4):396-398. Epub 2017 Sep 18.

Emergency Department, Usak University Research and Training Hospital, Usak, Turkey.

Ventricular septal (VS) rupture after acute myocardial infarction (AMI) is an uncommon complication in the reperfusion era. Bedside echocardiography (BECH) continues to be a strong diagnostic tool for emergency physicians treating dyspneic patients, especially for decision-making on the management strategies to use with these unstable patients. In the case we present here, a patient is diagnosed with a delayed mechanical complication after AMI, and a swift management plan is made with the aid of point-of-care BECH. Read More

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August 2018
3 Reads

Subcutaneous Granuloma Annulare.

Acta Dermatovenerol Croat 2017 Dec;25(4):292-294

Mihaela Paula Toader MD, PhD, T. Popa University of Medicine and Pharmacy, Iasi, Romania, 16 Universitatii str. 700115, Iasi, Romania;

Dear Editor, Subcutaneous granuloma annulare (SGA) is considered a rare clinical variant of granuloma annulare, a common self-healing chronic inflammatory disorder that may appear in childhood as well as in adult age (1-3). A 29-year-old female patient reported the onset of several small subcutaneous nodules on the dorsal aspect of the second interphalangeal joint of the left medius finger and the left elbow, accompanied by vague joint pain, had occurred 13 years ago. Specific markers for rheumatoid arthritis were negative, leading to a diagnosis of sero-negative rheumatoid arthritis, for which treatment with methotrexate was initiated. Read More

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December 2017
5 Reads

Mohs micrographic surgery with melanoma antigen recognized by T cells 1 (MART-1) immunostaining for atypical intraepidermal melanocytic proliferation.

J Am Acad Dermatol 2018 Dec 10;79(6):1109-1116.e1. Epub 2018 Jul 10.

Department of Dermatology, University of Pennsylvania Health System, Philadelphia, Pennsylvania.

Background: The efficacy of Mohs micrographic surgery (MMS) for atypical intraepidermal melanocytic proliferation (AIMP) is unknown.

Objective: To ascertain the frequency of diagnostic change to melanoma (upstaging) and the frequency of local recurrence after MMS for AIMP. A secondary outcome was the frequency of subclinical spread (defined as the requirement for >1 stage of MMS to achieve tumor-free margins). Read More

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December 2018
9 Reads

Expression of Peripheral Node Addressins by Plasmacytic Plaque of Children, APACHE, TRAPP, and Primary Cutaneous Angioplasmacellular Hyperplasia.

Appl Immunohistochem Mol Morphol 2018 Jul;26(6):411-419

Department of Pathology, University of Valencia, Valencia, Spain.

High-endothelial venules are a common feature of 3 types of cutaneous pseudolymphomas: pretibial lymphoplasmacytic plaque (PLP) of children, acral pseudolymphomatous angiokeratoma of children (APACHE), and T-cell rich angiomatoid polypoid pseudolymphoma (TRAPP). In addition, primary cutaneous angioplasmacellular hyperplasia (PCAH) overlaps with these other 3 conditions. We intend to study the expression of peripheral node addressins in PLP, APACHE, TRAPP, and PCAH. Read More

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July 2018
4 Reads

Bioabsorbable screws, whatever the composition, can result in symptomatic intra-osseous tibial tunnel cysts after ACL reconstruction.

Knee Surg Sports Traumatol Arthrosc 2018 Jun 30. Epub 2018 Jun 30.

Clinique du Sport Paris, 36, Boulevard Saint Marcel, 75005, Paris, France.

Purpose: To describe the clinical results of patients who underwent surgical treatment for a intra-osseous tibial tunnel cyst on a bioabsorbable interference screw following anterior cruciate ligament reconstruction (ACL).

Methods: This retrospective study included all patients who underwent surgery between 2004 and 2016 for an intra-osseous tibial tunnel cyst on bioabsorbable interference screw following ACL reconstruction. The diagnosis was suggested clinically by pretibial pain at the incision site, sometimes associated with a palpable subcutaneous nodule and then confirmed on MRI. Read More

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June 2018
10 Reads

Pretibial myxedema in a euthyroid patient.

Hormones (Athens) 2018 Mar 17;17(1):133-135. Epub 2018 Apr 17.

Division of Endocrinology, Police Medical Center of Thessaloniki, Monastiriou 326, 54121, Thessaloniki, Greece.

Pretibial myxedema (PM) is a rare extrathyroidal manifestation of Graves' disease (GD), usually during the hyperthyroid state, coexisting with orbitopathy. We describe a rare case of a biopsy-proven PM in a euthyroid patient, without history of GD or Hashimoto's thyroiditis. Assessment of commonly reported thyroid autoantibodies, such as thyroid peroxidase and thyroglobulin autoantibodies, thyroid stimulating immunoglobulins and thyroid binding inhibitory immunoglobulins, was negative. Read More

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March 2018
24 Reads

Post-traumatic fluctuant pretibial wound on the left leg.

Enferm Infecc Microbiol Clin 2018 May 25. Epub 2018 May 25.

Servicio de Cirugía Plástica y Reparadora, Hospital Universitario de Burgos, Burgos, España.

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[Modified anterolateral thigh perforator flap pedicled by cross-bridge microvascular anastomosis for repairing soft tissue defects in middle and lower segments of leg].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017 Oct;31(10):1240-1244

Department of Hand and Foot Microsurgery, Clinical Medicine College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou Jiangsu, 225001, P.R.China.

Objective: To explore the effectiveness of modified anterolateral thigh perforator flap pedicled by cross-bridge microvascular anastomosis in treatment of soft tissue defects in the middle and lower segments of the leg.

Methods: Between March 2011 and June 2015, 15 cases with skin and soft tissue defects in the middle and lower segments of the legs were treated. There were 9 males and 6 females, aged 22-48 years (mean, 32. Read More

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October 2017

Thyrotropin Receptor Antibodies-An Overview.

Ophthalmic Plast Reconstr Surg 2018 Jul/Aug;34(4S Suppl 1):S20-S27

Department of Medicine and Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, U.S.A.

Purpose: Thyroid autoimmunity affects approximately 5% of the population, and its investigation relies heavily on the use of autoantibodies. Thyroid stimulating hormone receptor (TSHR) autoantibodies (TRAb) play a central role in the evaluation of Graves disease (GD), Graves ophthalmopathy (GO) and pretibial myxedema (PTM). However, there is still controversy regarding overall TRAb assay diagnostic accuracy and their prognostic utility. Read More

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August 2018
4 Reads

Fundamental supply of skin blood flow in the Chinese Han population: Measurements by a full-field laser perfusion imager.

Skin Res Technol 2018 Nov 8;24(4):656-662. Epub 2018 May 8.

Institute of Dermatology and Department of Dermatology at NO.1 Affiliated Hospital, Anhui Medical University, Hefei, Anhui, China.

Background: Skin blood flow is believed to link with many diseases, and shows a significant heterogeneity. There are several papers on basal cutaneous microcirculation perfusion in different races, while the data in Chinese is vacant.

Objective: The aim was to establish the database of absolute fundamental supply of skin blood flow in the Chinese Han population. Read More

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November 2018
8 Reads

Pretibial Located Stewart-Treves Syndrome: Uncommon Presentation in a Bulgarian Patient!

Open Access Maced J Med Sci 2018 Apr 14;6(4):663-665. Epub 2018 Apr 14.

Helios Klinikum GMBH - Dermatology, Venereology and Allergology, Hildesheim, Germany.

Background: The Stewart-Treves syndrome with localisation in the region of the lower extremities is not something unusual as clinical pathology, but the clinical diagnostics is rather difficult, and it can be further complicated maximally because of: the similar locoregional findings in patients with other cutaneous malignancies.

Case Report: Presented is a rare form of an epithelioid variant of the Stewart Treves syndrome in a woman, aged 81, localised in the region of the lower leg and significantly advanced only for 2 months. The diagnosis was confirmed histologically and immunohistochemically. Read More

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April 2018
4 Reads
1 Citation

Obesity-Associated Lymphedematous Mucinosis: Two Further Cases and Review of the Literature.

Dermatopathology (Basel) 2018 Jan-Mar;5(1):16-20. Epub 2018 Feb 6.

Section of Dermatology, Department of Medical Science and Public Health, University of Cagliari, Cagliari, Italy.

Cutaneous mucinoses are a group of conditions characterized by increased amounts of acid mucin in the dermis. They can be generalized or localized and occur isolated or in the setting of systemic diseases. Obesity-associated lymphedematous mucinosis is a distinct variant of mucinosis occurring in obese patients without any thyroid dysfunction. Read More

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February 2018
3 Reads

A Man With Infiltrated Plaques on the Pretibial Area.

JAMA Dermatol 2018 Aug;154(8):955-956

Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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August 2018
7 Reads

A novel ECEL1 mutation expands the phenotype of distal arthrogryposis multiplex congenita type 5D to include pretibial vertical skin creases.

Am J Med Genet A 2018 Jun 16;176(6):1405-1410. Epub 2018 Apr 16.

Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

Arthrogryposis multiplex congenita (AMC) is a heterogeneous disorder characterized by multiple joint contractures often in association with other congenital abnormalities. Pretibial linear vertical creases are a rare finding associated with arthrogryposis, and the etiology of the specific condition is unknown. We aimed to genetically and clinically characterize a boy from a consanguineous family, presenting with AMC and pretibial vertical linear creases on the shins. Read More

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June 2018
2 Reads

Chylopericardium in a child with IgA nephropathy: a case report.

BMC Pediatr 2018 04 5;18(1):127. Epub 2018 Apr 5.

Department of Nephrology and Rheumatology, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.

Background: Chylopericardium effusion is characterized by the accumulation of milky effusion in the pericardium. It is often idiopathic but it can be secondary to trauma, chest radiation, tuberculosis and malignancy. If cardiac tamponade ensues, it becomes life-threatening. Read More

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April 2018
4 Reads

Multiple Recurrent Cyst Formation after Anterior Cruciate Ligament Reconstruction - A Case Report.

J Orthop Case Rep 2017 Nov-Dec;7(6):41-45

Department of Orthopaedics, Italian Hospital from Buenos Aires, Buenos Aires, Argentina.

Introduction: Anterior cruciate ligament (ACL) reconstruction is a "daily" surgery. Nevertheless, pretibial cyst formation is a very rare complication and may appear years after the reconstruction. Even more infrequent is the recurrence of this complication. Read More

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March 2018
2 Reads

Graves Disease in Central Ghana: Clinical Characteristics and Associated Factors.

Clin Med Insights Endocrinol Diabetes 2018 21;11:1179551418759076. Epub 2018 Mar 21.

Department of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

Background: Graves disease (GD) has increased in prevalence over the past decade in Africa. Despite this, the condition is not well described, especially in sub-Saharan Africa.

Objective: We have described the clinical characteristics and associated factors of GD in a cohort of patients attending a resource-limited setting tertiary hospital. Read More

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March 2018
5 Reads

Episodes of extreme lower leg pain caused by intraosseous varicose veins.

BMJ Case Rep 2018 Mar 27;2018. Epub 2018 Mar 27.

Department of Plastic Surgery, Academic Medical Center, Amsterdam, The Netherlands.

We present a case of a 67-year-old man with episodes of extreme pain of the right lower extremity that prevented him from walking and sleeping. The patient had a history of varices in both legs. Physical examination showed a pretibial varix of the right leg inferiorly from a painful spot. Read More

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March 2018
7 Reads

Coinheritance of 2 New Potentially Damaging Heterozygous COL7A1 Variants in a Family With Autosomal Dominant Epidermolysis Bullosa Pruriginosa.

Pediatr Dev Pathol 2018 Nov-Dec;21(6):580-584. Epub 2018 Mar 4.

1 Department of Dermatology, Sheffield Children's Hospital NHS Foundation Trust, Western Bank, Sheffield, UK.

Epidermolysis bullosa pruriginosa (EBP) is a rare subtype of EB which is characterized by intense pruritus with blistering and nodular or lichenoid lesions most prominent on the lower extremities. It is caused by variants in COL7A1 which encodes for type VII collagen. There is wide phenotypic and genotypic variability between affected individuals. Read More

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December 2018
4 Reads

Splice site mutation in COL7A1 resulting in aberrant in-frame transcripts identified in a case of recessive dystrophic epidermolysis bullosa, pretibial.

J Dermatol 2018 Jun 3;45(6):742-745. Epub 2018 Mar 3.

Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

Dystrophic epidermolysis bullosa (DEB), pretibial, a rare subtype of epidermolysis bullosa (EB), is characterized by recurrent blisters and erosions predominantly on the pretibial region. We report the case of a 60-year-old Japanese woman with persistent blistering eruptions and scar formation on the pretibial region and elbows. Mutational analysis revealed a previously reported c. Read More

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June 2018
2 Reads

Advanced Pretibial Melanoma (APM): Clinicians Behaviour As Triggering Factor?

Open Access Maced J Med Sci 2018 Jan 31;6(1):64-66. Epub 2017 Dec 31.

Medical Institute of Ministry of Interior, Department of General, Vascular and Abdominal Surgery, General Skobelev 79, 1606 Sofia, Bulgaria.

Background: Pigmented lesions represent a broad spectrum of clinical conditions, both benign and malignant. The precise diagnosis is often a challenge, while the clinical diagnostic criteria could be misleading, as a result of the frequently atypical presentation of otherwise completely benign in nature lesions. The variety of therapeutic options for benign pigmented lesions including shave curettage, local laser destruction, electrocoagulation removal could sound enticingly both for the physician and patient, but they destroy the possibility for histological examination and provide a deceptively feeling of calm, that the problem is solved. Read More

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January 2018
7 Reads

[Radiologic observation of the blood supply changes around the knee with osteoarthritis].

Zhongguo Gu Shang 2017 Aug;30(8):701-706

The 4th Department of Joint Surgery, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China;

Objective: To compare blood supply changes around the knee joint between normal and osteoarthritis knee.

Methods: From June 2014 to June 2015, 30 patients with knee osteoarthritis and 30 healthy adults were recruited. In osteoarthritis group, there were 9 males and 21 females, with a mean age of (65. Read More

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August 2017
1 Read

Imatinib-induced diffuse hyperpigmentation of the oral mucosa, the skin, and the nails in a patient affected by chronic myeloid leukemia: report of a case and review of the literature.

Int J Dermatol 2018 Jul 8;57(7):784-790. Epub 2018 Feb 8.

Dermatology Unit, Surgical, Medical and Dental Department of Morphological Sciences related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.

Background: Imatinib mesylate is a tyrosine-kinase inhibitor used as the first-line treatment in chronic myeloid leukemia patients, but it is also indicated for other hematological diseases and solid tumors. Imatinib treatment is often associated with hypopigmentation, but only a few cases of hyperpigmentation are described in literature.

Methods: We are reporting the first case of imatinib-related hyperpigmentation involving the oral mucosa, skin, and nails in a patient affected by chronic myeloid leukemia and treated with imatinib since 2002. Read More

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July 2018
14 Reads

Localized pretibial bullous pemphigoid arising in a patient on pembrolizumab for metastatic melanoma.

J Dtsch Dermatol Ges 2018 Feb 1;16(2):196-198. Epub 2018 Feb 1.

Department of Dermatology, University of California Irvine, Irvine, California, USA.

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February 2018
1 Read

Response to topical halcinonide following fractional carbon dioxide laser pretreatment in a pretibial myxedema patient.

Indian J Dermatol Venereol Leprol 2018 Nov-Dec;84(6):763

Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

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January 2018
3 Reads

Pretibial dystrophic epidermolysis bullosa.

An Bras Dermatol 2017 ;92(5 Suppl 1):126-128

Department of Dermatopathology of the Department of Anatomic Pathology, Santa Casa de Misericórdia de São Paulo - São Paulo (SP), Brazil.

Epidermolysis bullosa is a group of mechano-bullous genetic disorders caused by mutations in the genes encoding structural proteins of the skin. Dystrophic epidermolysis bullosa is caused by mutations in the COL7A1 gene encoding collagen VII, the main constituent of anchoring fibrils. In this group, there are autosomal dominant and recessive inheritances. Read More

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March 2018
4 Reads

Keystone-Designed Perforator Island Flaps for the Coverage of Traumatic Pretibial Defects in Patients With Comorbidities.

Int J Low Extrem Wounds 2017 Dec;16(4):302-309

2 Department of Plastic and Reconstructive surgery, Konyang University Hospital, University of Konyang College of Medicine, Metropolitan City Daejeon, Korea.

Reconstruction of pretibial skin and soft-tissue defects remains a challenge because this area has less underlying tissues and limited tissue mobility. Here, we present a retrospective review of our experience with pretibial reconstruction using the keystone-designed perforator island flap (KDPIF) in patients with comorbidities. All defects resulted from nononcological causes. Read More

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December 2017
8 Reads

Outpatient negative pressure dressing therapy for pretibial lacerations in a patient with high anaesthetic risk: a case study.

J Wound Care 2017 Dec;26(12):762-764

Lead Nurse, Burns and Plastic Surgery, Plastic Surgery Department, The Royal London Hospital, Barts Health NHS Trust, London, UK.

Pretibial lacerations are a common cause of presentation to accident and emergency departments. The management of these wounds is contentious with a variation in practise between individual institutions. We present the case of a 49-year-old female with a background of pulmonary atresia and associated pulmonary hypertension, who underwent successful outpatient negative pressure wound therapy (NPWT) for three pretibial lacerations. Read More

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December 2017
5 Reads

Compression stockings as an effective treatment for erythema nodosum: Case series.

Int J Womens Dermatol 2017 Dec 29;3(4):231-233. Epub 2017 Sep 29.

Department of Medicine, Division of Dermatology, University of Arizona, Tucson, AZ.

Erythema nodosum (EN) is a septal panniculitis that is characterized clinically by tender, erythematous, subcutaneous nodules that are predominately localized on the pretibial lower legs. EN affects women more than men and can be idiopathic or secondary to another disease process such as infection or an immune response. Treatment options for erythema nodosum are suboptimal and often involve significant side effects or require a change in lifestyle. Read More

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December 2017
1 Read

Dermatologic manifestations of endocrine disorders.

Transl Pediatr 2017 Oct;6(4):300-312

The Ohio State University College of Medicine, Columbus, OH, USA.

The skin serves as a window for clinicians to understand, diagnose, and monitor endocrine disease. Dermatologic manifestations of endocrinopathies contribute significantly to an individual's health and quality of life. In this review, we outline various disorders of the hypothalamic-pituitary axis, thyroid gland, pancreas, adrenal gland, and androgen axis as well as hereditary endocrine syndromes. Read More

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October 2017
10 Reads

Delayed Tibial Osteomyelitis after Anterior Cruciate Ligament Reconstruction with Hamstrings Autograft and Bioabsorbable Interference Screw: A Case Report and Review of the Literature.

Case Rep Orthop 2017 15;2017:6383526. Epub 2017 Oct 15.

Boca Care Orthopedics, Florida Atlantic University College of Medicine, Boca Raton, FL 33431, USA.

Osteomyelitis following arthroscopically assisted anterior cruciate ligament (ACL) reconstruction has rarely been reported in the literature. We report a case of a 20-year-old female who had delayed tibial osteomyelitis and a pretibial cyst with culture-positive, oxacillin sensitive 15 months after an ACL reconstruction with hamstring autograft. Soft tissue fixation within the tibial tunnel was with a poly-L-D-lactic acid (PLDLA) bioabsorbable interference screw. Read More

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October 2017
4 Reads

Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids

Turk J Med Sci 2017 11 13;47(5):1590-1592. Epub 2017 Nov 13.

Background/aim: Idiopathic granulomatous mastitis (IGM) is a rare, chronic inflammatory disease of the breast. Erythema nodosum (EN) is a rare extramammary manifestation of IGM. The purpose of this study is to determine the clinical and demographic characteristics of 11 IGM and EN patients and to evaluate the efficacy of methylprednisolone treatment. Read More

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November 2017
10 Reads

Pretibial myxoedema without thyroid associated orbitopathy in a patient with Graves' disease.

Postgrad Med J 2018 04 18;94(1110):236. Epub 2017 Nov 18.

Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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April 2018
5 Reads

Recessive mutation in tetraspanin CD151 causes Kindler syndrome-like epidermolysis bullosa with multi-systemic manifestations including nephropathy.

Matrix Biol 2018 03 11;66:22-33. Epub 2017 Nov 11.

Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA. Electronic address:

Epidermolysis bullosa (EB) is caused by mutations in as many as 19 distinct genes. We have developed a next-generation sequencing (NGS) panel targeting genes known to be mutated in skin fragility disorders, including tetraspanin CD151 expressed in keratinocytes at the dermal-epidermal junction. The NGS panel was applied to a cohort of 92 consanguineous families of unknown subtype of EB. Read More

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March 2018
16 Reads
1 Citation
5.070 Impact Factor

Pretibial lacerations.

Br J Hosp Med (Lond) 2017 Nov;78(11):C162-C166

Consultant Plastic and Reconstructive Surgeon, Department of Plastic Surgery, Salisbury District Hospital, Salisbury.

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November 2017

Reconstruction of the Foot Using a Superficial Inferior Epigastric Artery Free Flap.

Arch Plast Surg 2017 Nov 26;44(6):545-549. Epub 2017 Oct 26.

Department of Plastic and Reconstructive Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

When foot reconstruction is performed in the pretibial area, the ankle, or the dorsum of the foot, the need for a reliable flap remains a challenge. We found that the superficial inferior epigastric artery (SIEA) free flap can be used as an alternative tool for this purpose, as it helps to solve the problems associated with other flaps. We describe 2 cases in which we reconstructed the foot using an SIEA free flap, which was pliable enough to fit the contours of the area. Read More

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November 2017
11 Reads

The management of pretibial lacerations.

Ann R Coll Surg Engl 2017 Nov 15;99(8):637-640. Epub 2017 Sep 15.

Department of Plastic and Reconstructive Surgery, Addenbrooke's Hospital, University of Cambridge , Cambridge , UK.

Introduction Pretibial lacerations are common injuries, often presenting in the elderly and infirm. Unclear management pathways often result in inappropriate care. We identify patient demographics, morbidity risk factors, injury severity and management options. Read More

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November 2017
2 Reads

Treatment of pretibial myxedema with intralesional immunomodulating therapy.

Ther Clin Risk Manag 2017 8;13:1189-1194. Epub 2017 Sep 8.

Department of Endocrinology and Nephrology, Chongqing Emergency Medical Hospital (The Fourth People's Hospital of Chongqing).

Objective: Local immune regulation therapy has been one of the therapeutic methods used for the treatment of autoimmune thyroid disease in patients with pretibial myxedema (PTM). However, the poor response rate and high recurrence rate are still major problems. Whether a premixed corticosteroid, compound betamethasone, could enhance remission rate and decrease recurrence rate in patients with PTM was investigated in the present study. Read More

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September 2017
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