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    Three-dimensional printing in cardiology: Current applications and future challenges.
    Cardiol J 2017 May 25. Epub 2017 May 25.
    Department of Cardiology, Zhengzhou University People's Hospital (Henan Provincial People's Hospital), Zhengzhou, Henan, 450003, China.
    Three-dimensional (3D) printing has attracted a huge interest in recent years. Broadly speaking, it refers to the technology which converts a predesigned virtual model to a touchable object. In clinical medicine, it usually converts a series of two-dimensional medical images acquired through computed tomography, magnetic resonance imaging or 3D echocardiography into a physical model. Read More

    Analysis of factors affecting the development of hypocalcaemia after multinodular goitre surgery.
    Pol Przegl Chir 2017 Apr;89(2):26-30
    3 University Reaserch Hospital named after professor Kornel Gibiński of the Medical Univeristy of Silesia in Katowice, Ward of Alimentary Canal Surgery, Ward supervisor prof. Paweł lampe.
    Introduction: Thyroidectomy is a common surgery performed especially in treatment of multinodular goitre. The most common post-thyroidectomy complication is a postoperative hypocalcaemia, and the percentage of postoperative hypoparathyroidism could reach even 50%. Tested group and methods: A forward-looking, randomized testing was done on a group of 113 women being subject to multinodular goitre surgery. Read More

    Multivariable Analysis of Factors Affecting Length of Stay and Hospital Charges After Atlantoaxial Fusion.
    Cureus 2017 Apr 18;9(4):e1173. Epub 2017 Apr 18.
    Department of Neurosurgery, University of Utah.
    Background: Atlantoaxial fusion is an effective procedure for treating degenerative, traumatic, and congenital abnormalities that result in upper cervical instability; however, data on which factors affect the length of stay and hospitalization-related charges are limited. The purpose of this study was to evaluate the pre-, intra-, and postoperative variables that affect these healthcare cost factors for patients undergoing posterior atlantoaxial fusion.

    Methods: We retrospectively identified from a clinical database 59 patients who underwent isolated posterior atlantoaxial fusion at a single institution from 2010 to 2015. Read More

    Point-of-care haemostasis and coagulation monitoring in cardiac surgery at IRCCS Policlinico San Donato.
    Eur Heart J Suppl 2016 Apr 29;18(Suppl E):E42-E48. Epub 2016 Apr 29.
    Department of Cardiothoracic and Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, Via Morandi 30, 20097 San Donato Milanese, Milan, Italy.
    A rational management of perioperative and postoperative bleeding in modern cardiac surgery requires a thorough application of point-of-care (POC) monitoring in order to prevent and readily treat alterations of the haemostatic process. Preoperative platelet dysfunction, residual heparin after extracorporeal circulation, coagulation factors, and/or fibrinogen deficiency could be ruled out and specifically addressed with an appropriate treatment. Our approach includes preoperative platelet function testing of patients administered with thienopyridines or ticagrelor within 7-10 days before planned surgery and platelet function testing-based surgery timing. Read More

    Cataract surgery practices in the United States Veterans Health Administration.
    J Cataract Refract Surg 2017 Apr;43(4):543-551
    From the Program in Liberal Medical Education (Havnaer), Brown University, the Division of Ophthalmology (Havnaer, Greenberg), the Warren Alpert Medical School, Brown University, and the Section of Ophthalmology (Havnaer, Greenberg), Providence Veterans Administration Medical Center, Providence, Rhode Island, the Section of Ophthalmology (Cockerham), Palo Alto Veterans Administration Medical Center and the Departments of Ophthalmology and Pathology (Cockerham), Stanford University School of Medicine, Palo Alto, California, the Department of Quantitative Health Sciences (Clark), University of Massachusetts Medical School, Worcester, Massachusetts, and the Section of Ophthalmology, Veterans Administration Tennessee Valley Healthcare System and Vanderbilt Eye Institute (Chomsky), Nashville, Tennessee, USA.
    Purpose: To describe current cataract surgery practices within the United States Veterans Health Administration (VHA).

    Setting: Veterans Health Administration hospitals in the U.S. Read More

    Minimal access surgery compared to laparotomy for secondary surgical cytoreduction in patients with recurrent ovarian carcinoma: Perioperative and oncologic outcomes.
    Gynecol Oncol 2017 May 17. Epub 2017 May 17.
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA. Electronic address:
    Objectives: To assess the perioperative outcomes of minimal access surgery (MAS) in secondary surgical cytoreduction (SSCR) for recurrent epithelial ovarian cancer (ROC); to compare oncologic outcomes with laparotomy (LAP).

    Methods: Using an institutional database, we identified all patients with ROC undergoing SSCR from 1/5/09-6/14/14. Selection for MAS or LAP was based on surgeon preference. Read More

    A preliminary exploration of the intravoxel incoherent motion applied in the preoperative evaluation of mediastinal lymph node metastasis of lung cancer.
    J Thorac Dis 2017 Apr;9(4):1073-1080
    Department of Thoracic Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
    Background: The aim of this study was to investigate the diagnostic value of the intravoxel incoherent motion (IVIM) for distinguishing non-metastatic from metastatic mediastinal lymph nodes in lung cancer.

    Methods: IVIM-diffusion weighted imaging (DWI) exams were performed preoperatively on 66 patients with lung cancer from October 2015 to June 2016 in Beijing Chao-Yang Hospital, Capital Medical University. Fifty patients underwent enhanced chest computed tomography (CT) in our hospital, while the other 16 patients already had enhanced chest CT images when they were admitted. Read More

    Operating environment for awake brain surgery - Choice of tests.
    Neurochirurgie 2017 May 15. Epub 2017 May 15.
    Department of Neurology, Neuropsychology and Speech Therapy Unit, CM2R, Poitiers University Hospital, 86021 Poitiers, France.
    Introduction: The indication for awake brain surgery depends on a prerequisite, i.e. recognition that the brain area concerned is truly eloquent, and identification of one or more functions that must be preserved. Read More

    Preoperative Pain Neuroscience Education Combined With Knee Joint Mobilization for Knee Osteoarthritis: A Randomized Controlled Trial.
    Clin J Pain 2017 May 16. Epub 2017 May 16.
    *Department of Physical Therapy, University of Valencia, Valencia, Spain †Departments of Physiotherapy, Human Physiology and Anatomy, Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Brussel ∥MovAnt, Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp ¶Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium ‡Pain in Motion International Research Group §School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
    Objectives: This study aimed to first compare the effects of a preoperative treatment combining pain neuroscience education (PNE) with knee joint mobilization versus biomedical education with knee joint mobilization on central sensitization (CS) in patients with knee osteoarthritis, both before and after surgery. Second, we wanted to compare the effects of both interventions on knee pain, disability, and psychosocial variables.

    Materials And Methods: Forty-four patients with knee osteoarthritis were allocated to receive 4 sessions of either PNE combined with knee joint mobilization or biomedical education with knee joint mobilization before surgery. Read More

    Early neurocognitive improvements following parathyroidectomy for primary hyperparathyroidism.
    Laryngoscope 2017 May 16. Epub 2017 May 16.
    Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, U.S.A.
    Objectives: To establish a time frame for postoperative improvements in neurocognitive function in patients who undergo parathyroidectomy for primary hyperparathyroidism by utilizing repeat neuropsychological assessment at multiple time points before and after surgery.

    Study Design: Prospective cohort study.

    Methods: A prospective study was conducted at a tertiary academic medical center between August 2014 and December 2015, including 50 patients with primary hyperparathyroidism who underwent parathyroidectomy. Read More

    Cardiopulmonary Exercise Testing and Surgery.
    Ann Am Thorac Soc 2017 May 16. Epub 2017 May 16.
    University of Southampton, Anaesthesia and Critical Care Research Unit, Southampton, Hampshire, United Kingdom of Great Britain and Northern Ireland ;
    The surgical patient population is increasingly elderly and comorbid and poses challenges to perioperative physicians. Accurate pre-operative risk stratification is important to direct perioperative care. Reduced aerobic fitness is associated with increased post-operative morbidity and mortality. Read More

    Total haemoglobin mass, but not haemoglobin concentration, is associated with preoperative cardiopulmonary exercise testing-derived oxygen-consumption variables.
    Br J Anaesth 2017 May;118(5):747-754
    Division of Surgery and Interventional Science, University College London, London, UK.
    Background: Cardiopulmonary exercise testing (CPET) measures peak exertional oxygen consumption ( V˙O2peak ) and that at the anaerobic threshold ( V˙O2 at AT, i.e. the point at which anaerobic metabolism contributes substantially to overall metabolism). Read More

    Preoperative staging of Rectal Cancer using Magnetic Resonance Imaging: comparison with pathological staging.
    Minerva Chir 2017 May 11. Epub 2017 May 11.
    Department of Surgical Sciences, Radiology Institute, University of Turin, Turin, Italy.
    Background: To evaluate the accuracy of Magnetic Resonance (MR) in loco-regional staging of rectal cancer by comparing the MR results with histologic findings, considered as standard reference.

    Methods: Between July 2013 and March 2015, fifty-two patients, 27 (51.9%) males, age 66. Read More

    The effect of desflurane versus propofol anesthesia on postoperative delirium in elderly obese patients undergoing total knee replacement: A randomized, controlled, double-blinded clinical trial.
    J Clin Anesth 2017 Jun 14;39:17-22. Epub 2017 Mar 14.
    Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA.
    Study Objective: The goal of this study was to investigate the incidence of delirium, wake-up times and early post-operative cognitive decline in one hundred obese elderly patients undergoing total knee arthroplasty.

    Design: Prospective randomized trial.

    Settings: Operating room, postoperative recovery area, hospital wards. Read More

    Analysis of prognostic values of various PET metrics in preoperative FDG PET for early stage bronchial carcinoma for progression free and overall survival: significantly increased glycolysis is a predictive factor.
    J Nucl Med 2017 May 10. Epub 2017 May 10.
    University Hospital Zurich,Nuclear Medicine Department, Switzerland.
    Purpose: To assess various volume based PET quantification metrics including: metabolic tumor volume (MTV) and total lesion glycolysis (TLG) with different thresholds as well as background activity based PET metrics (Background Subtracted Lesion activity (BSL) and Volume (BSV)) as prognostic markers for progression free and overall survival (PFS, OS) in early stage I and II non-small cell lung cancer (NSCLC) after resection. Patients and Methods: 133 patients received an adequate FDG PET/CT scan prior to surgery between January 2003 and December 2010. All PET activity metrics showed a skewed distribution and were log-transformed before calculating the Pearson correlation coefficients (PCC). Read More

    Impact of using a local protocol in preoperative testing: blind randomized clinical trial.
    Rev Col Bras Cir 2017 Jan-Feb;44(1):54-63
    - Gaffree and Guinle University Hospital, Federal University of the State of Rio de Janeiro, Service of Anesthesiology, Rio de Janeiro, Rio de Janeiro State, Brazil.
    Objective:: to evaluate the impact of the use of a local protocol of preoperative test requests in reducing the number of exams requested and in the occurrence of changes in surgical anesthetic management and perioperative complications.

    Methods:: we conducted a randomized, blinded clinical trial at the Gaffrée and Guinle University Hospital with 405 patients candidates for elective surgery randomly divided into two groups, according to the practice of requesting preoperative exams: a group with non-selectively requested exams and a protocol group with exams requested according to the study protocol. Studied exams: complete blood count, coagulogram, glycemia, electrolytes, urea and creatinine, ECG and chest X-ray. Read More

    Clinical presentation and disease course of patients with esophagogastric junction outflow obstruction.
    Dis Esophagus 2017 Jun;30(6):1-6
    Department of Internal Medicine, Division of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
    Esophagogastric junction outflow obstruction, characterized by preserved peristalsis in conjunction with an elevated integrated relaxation pressure, can result from specific anatomic variants or may represent achalasia in evolution. There is limited information on the clinical significance of this diagnosis. The aim of this study is to describe the clinical characteristics and outcomes in our cohort of patients with esophagogastric junction outflow obstruction. Read More

    RANK-ligand and osteoprotegerin as biomarkers in the differentiation between periprosthetic joint infection and aseptic prosthesis loosening.
    World J Orthop 2017 Apr 18;8(4):342-349. Epub 2017 Apr 18.
    Max J Friedrich, Matthias D Wimmer, Jan Schmolders, Andreas C Strauss, Milena M Ploeger, Hendrik Kohlhof, Dieter C Wirtz, Sascha Gravius, Thomas M Randau, Department of Orthopedics and Trauma Surgery, University Clinic of Bonn, 53125 Bonn, Germany.
    Aim: To assess serum levels of RANK-ligand (RANKL) and osteoprotegerin (OPG) as biomarkers for periprosthetic joint infection (PJI) and compare their accuracy with standard tests.

    Methods: One hundred and twenty patients presenting with a painful total knee or hip arthroplasty with indication for surgical revision were included in this prospective clinical trial. Based on standard diagnostics (joint aspirate, microbiological, and histological samples) and Musculoskeletal Infection Society consensus classification, patients were categorized into PJI, aseptic loosening, and control groups. Read More

    Characterization and Preoperative Risk Analysis of Leiomyosarcomas at a High-Volume Tertiary Care Center.
    Int J Gynecol Cancer 2017 May 2. Epub 2017 May 2.
    *Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of UPMC, Pittsburgh, PA; †Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR; and ‡Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA.
    Introduction: Uterine morcellation in minimally invasive surgery has recently come under scrutiny because of inadvertent dissemination of malignant tissue, including leiomyosarcomas commonly mistaken for fibroids. Identification of preoperative risk factors is crucial to ensure that oncologic care is delivered when suspicion for malignancy is high, while offering minimally invasive hysterectomies to the remaining patients.

    Objectives: The aim of this study was to characterize risk factors for uterine leiomyosarcomas by reviewing preoperative, intraoperative, and postoperative data with an emphasis on the presence of concurrent fibroids. Read More

    Decreased Binocular Summation in Strabismic Amblyopes and Effect of Strabismus Surgery.
    Strabismus 2017 May 2:1-8. Epub 2017 May 2.
    a Department of Ophthalmology , Stein Eye Institute, UCLA Medical Center , Los Angeles , CA.
    Purpose: Binocular summation (BiS) occurs when binocular visual function surpasses that of the better eye alone. We sought to evaluate whether strabismic amblyopia reduces BiS more than strabismus alone, and determine whether BiS improves in strabismic amblyopes after strabismus surgery.

    Methods: We prospectively recruited 15 patients with strabismic amblyopia who then underwent strabismus surgery. Read More

    Vitrectomy and Vitrector Port Needle Biopsy of Choroidal Melanoma for Gene Expression Profile Testing Immediately before Brachytherapy.
    Ophthalmology 2017 Apr 28. Epub 2017 Apr 28.
    Ophthalmology Associates, Louisville, Kentucky.
    Purpose: Transvitreal and transscleral needle biopsy can result in complications including vitreous hemorrhage and retinal detachment. This study evaluated a technique using 25-gauge vitrectomy as an adjunct to needle biopsy immediately before brachytherapy to minimize these complications and preserve good visual acuity.

    Design: Retrospective, observational case series. Read More

    Impact of platelet to lymphocyte ratio and metabolic syndrome on the prognosis of colorectal cancer patients.
    Onco Targets Ther 2017 18;10:2199-2208. Epub 2017 Apr 18.
    Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou.
    Objective: The aim of this study was to evaluate the prognostic value of both platelet to lymphocyte ratio (PLR) and metabolic syndrome (MetS) in colorectal cancer (CRC) patients.

    Patients And Methods: We retrospectively enrolled 1,163 CRC patients. Preoperative values of PLR were stratified into three groups according to cut-off values of 120 and 220. Read More

    Accurate 3D reconstruction of bony surfaces using ultrasonic synthetic aperture techniques for robotic knee arthroplasty.
    Comput Med Imaging Graph 2017 Apr 19;58:23-32. Epub 2017 Apr 19.
    Department of Electronic and Electrical Engineering, University of Strathclyde, Glasgow, United Kingdom.
    Robotically guided knee arthroplasty systems generally require an individualized, preoperative 3D model of the knee joint. This is typically measured using Computed Tomography (CT) which provides the required accuracy for preoperative surgical intervention planning. Ultrasound imaging presents an attractive alternative to CT, allowing for reductions in cost and the elimination of doses of ionizing radiation, whilst maintaining the accuracy of the 3D model reconstruction of the joint. Read More

    Considerations for refractive surgery in the glaucoma patient.
    Curr Opin Ophthalmol 2017 Apr 25. Epub 2017 Apr 25.
    Department of Ophthalmology, Glaucoma Service Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.
    Purpose Of Review: Given the popularity of keratorefractive surgery, and an aging populous of patients who have undergone these procedures, there is an increasing need for updated management protocols. This is particularly relevant for patients with chronic progressive diseases such as glaucoma, due to the variety of related diagnostic and management challenges inherent to these diseases. Here, we will review the current literature to provide an update on the management of patients with glaucoma who are undergoing, or have had laser ablative refractive surgery. Read More

    The effects of a data driven maximum surgical blood ordering schedule on preoperative blood ordering practices.
    Hematology 2017 Apr 25:1-7. Epub 2017 Apr 25.
    c Department of Pathology , University of Pittsburgh , Pittsburgh, PA, USA.
    Objectives: The maximum surgical blood ordering schedule (MSBOS) provides guidelines for pre-operative pre-transfusion testing for elective surgical procedures. This study compared blood ordering and utilization during the period when the MSBOS was created by achieving consensus between the blood bank and the various surgical specialties, and after the introduction of an MSBOS created by using department-specific red blood cell (RBC) transfusion data (data driven MSBOS, dMSBOS).

    Methods: The dMSBOS was created by analyzing 12 months of RBC transfusion data for each procedure across a regional health system. Read More

    Attempted Development of a Tool to Predict Anesthesia Preparation Time From Patient-Related and Procedure-Related Characteristics.
    Anesth Analg 2017 Apr 19. Epub 2017 Apr 19.
    From the Departments of *General Anesthesiology, Anesthesiology Institute; †Outcomes Research, Anesthesiology Institute; and ‡Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.
    Background: Operating room (OR) utilization generally ranges from 50% to 75%. Inefficiencies can arise from various factors, including prolonged anesthesia preparation time, defined as the period from induction of anesthesia until patients are considered ready for surgery. Our goal was to use patient-related and procedure-related factors to develop a model predicting anesthesia preparation time. Read More

    Clinical Significance of Preoperative Albumin and Globulin Ratio in Patients with Gastric Cancer Undergoing Treatment.
    Biomed Res Int 2017 23;2017:3083267. Epub 2017 Mar 23.
    Department of Clinical Laboratory, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dong Feng Road East, Guangzhou, Guangdong Province 510060, China.
    Background. The pretreatment albumin and globulin ratio (AGR) was an inflammation-associated factor which was related to the overall survival in various malignancies. The aim of this study was to evaluate the prognostic value of AGR in patients with gastric cancer. Read More

    The role of molecular diagnostic testing in the management of thyroid nodules.
    Expert Rev Mol Diagn 2017 Jun 28;17(6):567-576. Epub 2017 Apr 28.
    a Department of Surgery , New York Presbyterian-Weill Cornell Medicine , New York , NY , USA.
    Introduction: Fine needle aspiration (FNA) with cytologic examination remains the standard of care for investigation of thyroid nodules. However, as many as 30% of FNA samples are cytologically indeterminate for malignancy, which confounds clinical management. To reduce the burden of repeat diagnostic testing and unnecessary surgery, there has been extensive investigation into molecular markers that can be detected on FNA specimens to more accurately stratify a patient's risk of malignancy. Read More

    Late Recurrence of Early Stage Cervical Cancer more than 3 Years after Radical Hysterectomy with Pelvic Node Dissection.
    Oncol Res Treat 2017 20;40(5):270-276. Epub 2017 Apr 20.
    Background: The aim of this study was to compare the clinicopathological characteristics and outcomes of patients who developed late recurrence (> 3 years) of early stage cervical cancer after radical surgery with those of patients who developed early recurrence (≤ 3 years). We also investigated the risk factors of late recurrence.

    Methods: The records of 515 patients with early stage cervical cancer diagnosed between 1999 and 2015 were reviewed. Read More

    Short-term preoperative exercise therapy does not improve long-term outcome after lung cancer surgery: a randomized controlled study†.
    Eur J Cardiothorac Surg 2017 Apr 17. Epub 2017 Apr 17.
    Department of Thoracic and Endocrine Surgery, University Hospitals of Geneva, Geneva, Switzerland.
    Objectives: Poor aerobic fitness is a potential modifiable risk factor for long-term survival and quality of life in patients with lung cancer. This randomized trial evaluates the impact of adding rehabilitation (Rehab) with high-intensity interval training (HIIT) before lung cancer surgery to enhance cardiorespiratory fitness and improve long-term postoperative outcome.

    Methods: Patients with operable lung cancer were randomly assigned to usual care (UC, n  = 77) or to intervention group (Rehab, n  = 74) that entailed HIIT that was implemented only preoperatively. Read More

    Ancillary testing strategies in salivary gland aspiration cytology: A practical pattern-based approach.
    Diagn Cytopathol 2017 Apr 14. Epub 2017 Apr 14.
    Department of Pathology, Emory University, Atlanta, Georgia.
    Fine needle aspiration of salivary gland tumors is a common preoperative triage as it is useful in determining which patients should undergo surgical resection and in guiding the extent of surgery in those cases deemed appropriate for resection. While a specific diagnosis can be achieved on a cytologic specimen in many cases, there is also a considerable amount of morphologic diversity that prevents such confident preoperative classification and in these cases it can be a challenge to confidently determine if a tumor is benign or malignant. Recently, a pattern based risk stratification approach was proposed for salivary gland cytology in which basaloid neoplasms are separated by stromal characteristics and oncocytoid neoplasms are separated primarily by background material such as mucus. Read More

    Spontaneous cerebrospinal fluid fistula in the clivus.
    Eur Ann Otorhinolaryngol Head Neck Dis 2017 Apr 11. Epub 2017 Apr 11.
    Department of Otorhinolaryngology and Head and Neck Surgery, Bloque A Planta 4 Modulo 3, Hospital de Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, 90, Mas Casanovas, 08041 Barcelona, Spain.
    Introduction: Spontaneous cerebrospinal fluid (CSF) fistulas are infrequent and only 10 cases in the literature have been located in the clivus. We describe two new cases of CSF fistulas in this site and review the literature.

    Case Report: The first patient was a 52-year-old woman referred to our centre for intermittent rhinorrhea that had been diagnosed after an episode of meningitis. Read More

    Using the NSQIP Pancreatic Demonstration Project to Derive a Modified Fistula Risk Score for Preoperative Risk Stratification in Patients Undergoing Pancreaticoduodenectomy.
    J Am Coll Surg 2017 May 10;224(5):816-825. Epub 2017 Apr 10.
    Department of Surgery, University of Chicago, Chicago, IL; Department of Surgery, NorthShore University HealthSystem, Evanston, IL. Electronic address:
    Background: The Fistula Risk Score (FRS) is a clinical tool developed from single-institutional data using primarily intraoperative factors to characterize the risk of clinically relevant pancreatic fistula (CR-POPF) after pancreaticoduodenectomy. We developed a modified FRS based on objective, nationally accrued data that is more readily determined before resection.

    Study Design: The 2012 NSQIP Pancreatic Demonstration Project (PDP) was used to identify 1,731 pancreaticoduodenectomy resections over 14 months (2011 to 2012). Read More

    Management and Outcomes of Acute Surgical Patients at a District Hospital in Uganda with Non-physician Emergency Clinicians.
    World J Surg 2017 Apr 12. Epub 2017 Apr 12.
    Global Emergency Care Collaborative, Kampala, Uganda.
    Introduction: Acute surgical care services in rural Sub-Saharan Africa suffer from human resource and systemic constraints. Developing emergency care systems and task sharing aspects of acute surgical care addresses many of these issues. This paper investigates the degree to which specialized non-physicians practicing in a dedicated Emergency Department contribute to the effective and efficient management of acute surgical patients. Read More

    Severity of Preoperative Proteinuria is a Risk Factor for Overall Mortality in Patients Undergoing Nephrectomy.
    J Urol 2017 Apr 7. Epub 2017 Apr 7.
    Mayo Clinic, Department of Urology.
    Purpose: Chronic kidney disease may adversely affect survival following nephrectomy. Proteinuria is increasingly used as a marker for kidney disease. However, the relationship between preoperative proteinuria and survival following nephrectomy remains incompletely characterized. Read More

    Surgery-Related Contact Dermatitis: A Review of Potential Irritants and Allergens.
    J Allergy Clin Immunol Pract 2017 Apr 7. Epub 2017 Apr 7.
    Division of Allergy, Asthma and Immunology, Scripps Clinic, San Diego, Calif.
    Surgical procedures utilize an increasing number of medical products including antiseptics, anesthetics, gloves, suture materials, tissue adhesives, topical antibiotics, and bandages. Many of these products have irritant potential. Allergic contact dermatitis has also been reported. Read More

    Coagulopathies in cyanotic cardiac patients: An analysis with three point - of - care testing devices (Thromboelastography, rotational thromboelastometry, and sonoclot analyzer).
    Ann Card Anaesth 2017 Apr-Jun;20(2):212-218
    Department of Cardiac Anaesthesia, Cardio Thoracic Centre, All India Institute of Medical Sciences, New Delhi, India.
    Introduction: In the last few years, viscoelastic point-of-care (POC) coagulation devices such as thromboelastography (TEG), rotational thromboelastometry (ROTEM), and Sonoclot (SON) analyzer have been increasingly used in major surgeries for timely assessment and management of coagulopathies. The aim of the present study was to evaluate coagulation profile of cyanotic cardiac patients with TEG, ROTEM, and SON analyzer. In addition, we assessed the correlation of standard laboratory coagulation tests and postoperative chest drain output (CDO) with the parameters of POC testing devices. Read More

    Evaluation of the postoperative cognitive dysfunction in elderly patients with general anesthesia.
    Eur Rev Med Pharmacol Sci 2017 Mar;21(6):1346-1354
    Department of Anesthesiology, Department of General Surgery; The Affiliated Hospital of Shandong Traditional Chinese Medicine University, Jinan City, Shandong Province, China.
    Objective: The present study is aimed to study the neuron-specific enolase (NSE) and S100b proteins in the evaluation of postoperative cognitive dysfunction in elderly patients with general anesthesia.

    Patients And Methods: A total of 142 aged patients, who were treated with transurethral resection of the prostate (TURP) surgery under general anesthesia with propofol from June 2014 to December 2015, were randomly divided into two groups. The experiment group was given scopolamine butylbromide by intramuscular injection before the operation, while the control group had no preoperative intramuscular injection. Read More

    Effects of a Physical Activity Program on Cardiorespiratory Fitness and Pulmonary Function in Obese Women after Bariatric Surgery: a Pilot Study.
    Obes Surg 2017 Apr 7. Epub 2017 Apr 7.
    Physical Therapy Department, Cardiovascular and Metabolic Rehabilitation Laboratory, Federal University of Rio Grande do Norte, Campus Universitário, Caixa Postal 1524 Lagoa Nova CEP 59078-900, Natal, Rio Grande do Norte, Brazil.
    Background: In severely obese individuals, reducing body weight induced by bariatric surgery is able to promote a reduction in comorbidities and improve respiratory symptoms. However, cardiorespiratory fitness (CRF) reflected by peak oxygen uptake (VO2peak) may not improve in individuals who remain sedentary post-surgery. The objective of this study was to evaluate the effects of a physical training program on CRF and pulmonary function in obese women after bariatric surgery, and to compare them to a control group. Read More

    An Evaluation of Language in Brain Tumor Patients Using a New Cognitively Motivated Testing Protocol.
    Neuropsychology 2017 Apr 6. Epub 2017 Apr 6.
    Objective: To characterize the language impairments that occur in brain tumor patients using a cognitively oriented theoretical framework.

    Method: Forty-nine preoperative brain tumor patients completed a new testing protocol (the BLAST) which assesses 8 well documented, "core" cognitive skills required for language: auditory word recognition, accessing semantic knowledge, lexical selection, phonological encoding, verbal short-term memory, goal-driven language selection, verb retrieval, and articulatory-motor planning. Patients were unselected with respect to lesion location. Read More

    Observational cohort study examining apolipoprotein E status and preoperative neuropsychological performance as predictors of post-operative delirium in an older elective arthroplasty population.
    Age Ageing 2017 Apr 5:1-8. Epub 2017 Apr 5.
    Centre for Public Health, Institute of Clinical Sciences, Block B, Queens University Belfast, Royal Victoria Hospital, Belfast BT12 6BA, UK.
    Introduction: delirium following surgery is common and is associated with negative outcomes. Preoperative cognitive impairment has been shown to be a risk factor for post-operative delirium. Often the cognitive tests used are cumbersome. Read More

    Routine calcitonin measurement in nodular thyroid disease management: is it worthwhile?
    Ann Surg Treat Res 2017 Apr 24;92(4):173-178. Epub 2017 Mar 24.
    Division of Endocrine Surgery, Department of General Surgery, Ege University Hospital, Izmir, Turkey.
    Purpose: To evaluate the diagnostic accuracy of routine calcitonin measurement in patients with nodular thyroid disease.

    Methods: Consecutive patients with nodular thyroid disease (n = 640) were studied. Serum calcitonin levels were measured under basal conditions, and when basal values were between 10-100 pg/mL, testing was repeated after pentagastrin (PG) stimulation. Read More

    ASA physical status assignment by non-anesthesia providers: Do surgeons consistently downgrade the ASA score preoperatively?
    J Clin Anesth 2017 May 12;38:123-128. Epub 2017 Feb 12.
    Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, United States.
    Objective: The American Society of Anesthesiologists physical status (ASA-PS) is associated with increased morbidity and mortality in the perioperative period. When surgeries are scheduled by surgeons and their staff at our large institution a presumed ASA-PS is chosen. This is because our institution (and, anecdotally, others in our hospital system and elsewhere), recognizing the relationship between higher ASA-PS and poorer postoperative outcomes, requires all patients with higher ASA-PS levels (≥3) to undergo enhanced preoperative workup. Read More

    Patients' maximum acceptable waiting time for cataract surgery: a comparison at two time-points 7 years apart.
    Acta Ophthalmol 2017 Mar 30. Epub 2017 Mar 30.
    Department of Ophthalmology, KH Hietzing, Vienna, Austria.
    Purpose: To evaluate the maximum acceptable waiting time (MAWT) of cataract patients and assess the determinants of their perception of MAWT at two time-points 7 years apart.

    Methods: In 2007 (prior to the transformation of our cataract service to a day case unit) and 2014, 500 consecutive patients with cataract were asked to fill in a preoperative questionnaire addressing their MAWT to undergo cataract surgery. The patients' visual impairment (VF-14 score), education and social status were evaluated. Read More

    Botulinum toxin injection in the patients with Duane syndrome type 1.
    J Curr Ophthalmol 2017 Mar 12;29(1):50-53. Epub 2016 Nov 12.
    Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
    Purpose: To evaluate the efficacy of botulinum toxin injection in the patients with type 1 Duane syndrome and identify the predictive factors for success.

    Methods: Sixteen patients with esotropic type 1 Duane syndrome without history of ocular surgery were selected for this interventional case series. The botulinum toxin was injected in the medial rectus of all patients. Read More

    Renal and cardiac assessment of living kidney donor candidates.
    Nat Rev Nephrol 2017 Apr 3. Epub 2017 Apr 3.
    Department of Medicine, Division of Nephrology, Western University, 800 Commissioners Road East, London, Ontario N6A 4G5, Canada.
    Living kidney donation provides the best therapeutic outcomes for eligible patients with end-stage renal disease. To ensure suitability for living kidney donation, donor candidates undergo a thorough medical, surgical, and psychosocial evaluation by a multidisciplinary transplant assessment team. Numerous guidelines are available to assist clinicians in the process of donor evaluation and selection. Read More

    Hypersensitivity to Orthopedic Implants: A Review of the Literature.
    Rheumatol Ther 2017 Jun 31;4(1):45-56. Epub 2017 Mar 31.
    Department of Orthopaedic Surgery, Warren Alpert Medical School, Brown University, Providence, RI, USA.
    Awareness of rare etiologies for implant failure is becoming increasingly important. In addition to the overall increase in joint arthroplasties, revision surgeries are projected to increase dramatically in the coming years, with volume increasing up to seven-fold between 2005 and 2030. The literature regarding the relationship between metal allergy and implant failure is controversial. Read More

    Tangent screen perimetry in the evaluation of visual field defects associated with ptosis and dermatochalasis.
    PLoS One 2017 29;12(3):e0174607. Epub 2017 Mar 29.
    Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Purpose: To determine if tangent visual fields gathered during assessment of superior visual field deficits caused by blepharoptosis and dermatochalasis offer good correlation to clinical exam in a time and cost efficient manner.

    Methods: Prospective, observational case series. Subjects included all patients referred to a single surgeon (CCN) who underwent surgical correction of blepharoptosis and/or dermatochalasis. Read More

    Preoperative high-intensity training in frail old patients undergoing pulmonary resection for NSCLC.
    Open Med (Wars) 2016 19;11(1):443-448. Epub 2016 Nov 19.
    Department of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Piazza Miraglia, 2, 80138 Naples, Italy Phone:+390815665228, , E-mail:
    Thoracic surgery remains the better therapeutic option for non-small cell lung cancer patients that are diagnosed in early stage disease. Preoperative lung function assessment includes respiratory function tests (RFT) and cardio-pulmonary exercise testing (CPET). Vo2 peak, FEV1 and DLCO as well as recognition of performance status, presence of co-morbidities, frailty indexes, and age predict the potential impact of surgical resection on patient health status and survival risk. Read More

    Infant Motor Skills After a Cardiac Operation: The Need for Developmental Monitoring and Care.
    Ann Thorac Surg 2017 Mar 24. Epub 2017 Mar 24.
    Department of Cardiac Surgery, University of Michigan Mott Children's Hospital, Ann Arbor, Michigan; Department of Pediatrics, University of Michigan Mott Children's Hospital, Ann Arbor, Michigan.
    Background: Neurodevelopmental dysfunction is increasingly recognized as a common outcome of congenital heart defects and their treatment in infancy. The effects of the intensive care unit (ICU) experience and environment on these infants are unknown and potentially modifiable, but no validated metric is available for objective evaluation of early motor impairments in the ICU/hospital setting. The purpose of this study was to characterize the motor status of hospitalized infants after cardiac operations, including the development and field-testing of the Congenital Heart Assessment of Sensory and Motor Status (CHASMS) metric. Read More

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