8,445 results match your criteria Preoperative Testing


Machine-learning Models Predict 30-Day Mortality, Cardiovascular Complications, and Respiratory Complications After Aseptic Revision Total Joint Arthroplasty.

Clin Orthop Relat Res 2022 Jun 20. Epub 2022 Jun 20.

Department of Orthopaedic Surgery, Bone and Joint Sports Medicine Center, Naval Medical Center Portsmouth, Portsmouth, VA, USA.

Background: Aseptic revision THA and TKA are associated with an increased risk of adverse outcomes compared with primary THA and TKA. Understanding the risk profiles for patients undergoing aseptic revision THA or TKA may provide an opportunity to decrease the risk of postsurgical complications. There are risk stratification tools for postoperative complications after aseptic revision TKA or THA; however, current tools only include nonmodifiable risk factors, such as medical comorbidities, and do not include modifiable risk factors. Read More

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Impact of increasing total knee replacement constraint within a single implant line on coronal stability: an ex vivo investigation.

Arch Orthop Trauma Surg 2022 Jun 29. Epub 2022 Jun 29.

Division of Orthopaedics, Department of Orthopaedics, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Introduction: Despite the existence of diverse total knee implant designs, few data is available on the relationship between the level of implant constraint and the postoperative joint stability in the frontal plane and strain in the collateral ligaments. The current study aimed to document this relation in an ex vivo setting.

Materials And Methods: Six fresh-frozen lower limbs underwent imaging for preparation of specimen-specific surgical guides. Read More

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Nationally Validated Scoring System to Predict Unplanned Reoperation and Readmission after Breast Reduction.

Aesthetic Plast Surg 2022 Jun 28. Epub 2022 Jun 28.

Division of Plastic and Reconstructive Surgery, Department of Surgical Oncology, Fox Chase Cancer Center/ Temple University, 333 Cottman Avenue, Philadelphia, PA, 19111, USA.

Background: Reduction mammoplasty continues to be a commonly sought procedure with complication rates ranging from 4.3 to 8.2%. Read More

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Preoperative prediction of pelvic lymph nodes metastasis in prostate cancer using an ADC-based radiomics model: comparison with clinical nomograms and PI-RADS assessment.

Abdom Radiol (NY) 2022 Jun 28. Epub 2022 Jun 28.

Department of Radiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, 100034, China.

Purpose: To develop and test radiomics models based on manually corrected or automatically gained masks on ADC maps for pelvic lymph node metastasis (PLNM) prediction in patients with prostate cancer (PCa).

Methods: A primary cohort of 474 patients with PCa who underwent prostate mpMRI were retrospectively enrolled for PLNM prediction between January 2017 and January 2020. They were then randomly split into training/validation (n = 332) and test (n = 142) groups for model development and internal testing. Read More

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Mid-term Surgery Outcomes in Patients with COVID-19: Results from a Nationwide Analysis.

Ann Surg 2022 Jun 28. Epub 2022 Jun 28.

Department of Surgery, University of Maryland School of Medicine, Baltimore, MD.

Objective: Determine mid-term postoperative outcomes among COVID-19-positive patients compared to those who never tested positive before surgery.

Background: COVID-19 is thought to be associated with prohibitively high rates of postoperative complications. However, prior studies have only evaluated 30-day outcomes and most did not adjust for demographic, clinical, or procedural characteristics. Read More

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The pathological risk score: A new deep learning-based signature for predicting survival in cervical cancer.

Cancer Med 2022 Jun 28. Epub 2022 Jun 28.

Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Medicine and Engineering, Beihang University, Beijing, China.

Purpose: To develop and validate a deep learning-based pathological risk score (RS) with an aim of predicting patients' prognosis to investigate the potential association between the information within the whole slide image (WSI) and cervical cancer prognosis.

Methods: A total of 251 patients with the International Federation of Gynecology and Obstetrics (FIGO) Stage IA1-IIA2 cervical cancer who underwent surgery without any preoperative treatment were enrolled in this study. Both the clinical characteristics and WSI of each patient were collected. Read More

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Prevalence of breast fibroadenoma in healthy physical examination population in Guangdong province of China: a cross-sectional study.

BMJ Open 2022 Jun 27;12(6):e057080. Epub 2022 Jun 27.

Breast Center, Department of general surgery, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China

Objective: To provide an accurate assessment of the prevalence of breast fibroadenoma in a large population and to confirm the diagnostic accuracy of ultrasound for fibroadenoma.

Design: This was a cross-sectional survey.

Setting: This research was conducted at Nanfang Hospital, Guangzhou, Guangdong, China. Read More

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Development and Validation of Machine Learning-Based Predictive Model for Clinical Outcome of Decompression Surgery for Lumbar Spinal Canal Stenosis.

Spine J 2022 Jun 24. Epub 2022 Jun 24.

Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan.

Background Context: Although the results of decompression surgery for lumbar spinal canal stenosis (LSS) are favorable, it is still difficult to predict the postoperative HRQoL of patients before surgery.

Purpose: The purpose of this study was to develop and validate a machine learning model to predict the postoperative outcome of decompression surgery for patients with LSS.

Study Design/setting: A multicentered retrospective study. Read More

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Management of thyroid nodules.

Lancet Diabetes Endocrinol 2022 Jul;10(7):540-548

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

In the past 30 years, there has been a substantial rise in the detection of thyroid nodules. Largely asymptomatic, thyroid nodules are most often incidental findings that typically pose minimal risk. Data supporting these findings show a rapid rise in the incidental detection of thyroid nodules and cancer, but minimal effect on mortality rates, despite treatment. Read More

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Presurgical olfactory function as an indicator of the outcome of functional endoscopic sinus surgery in chronic rhinosinusitis with nasal polyps.

Eur Arch Otorhinolaryngol 2022 Jun 24. Epub 2022 Jun 24.

Smell and Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.

Introduction: Chronic rhinosinusitis with nasal polyps (CRSwNP) often leads to impaired olfactory function and reduced quality of life. When conservative treatments such as nasal irrigation and topical steroids fail, functional endoscopic sinus surgery (FESS) is often necessary, because it improves symptoms and enhances quality of life.

Materials And Methods: A total of 88 patients was included in this prospective study. Read More

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A Dual-Energy CT Radiomics of the Regional Largest Short-Axis Lymph Node Can Improve the Prediction of Lymph Node Metastasis in Patients With Rectal Cancer.

Front Oncol 2022 7;12:846840. Epub 2022 Jun 7.

Department of Medical Imaging, The Affiliated Hospital of Jiangsu University, Zhenjiang, China.

Objective: To explore the value of dual-energy computed tomography (DECT) radiomics of the regional largest short-axis lymph nodes for evaluating lymph node metastasis in patients with rectal cancer.

Materials And Methods: One hundred forty-one patients with rectal cancer (58 in LNM+ group, 83 in LNM- group) who underwent preoperative total abdominal DECT were divided into a training group and testing group (7:3 ratio). After post-processing DECT venous phase images, 120kVp-like images and iodine (water) images were obtained. Read More

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Individualized, Additively Manufactured Drug-Releasing External Ear Canal Implant for Prevention of Postoperative Restenosis: Development, In Vitro Testing, and Proof of Concept in an Individual Curative Trial.

Pharmaceutics 2022 Jun 11;14(6). Epub 2022 Jun 11.

Department of Otorhinolaryngology, Head and Neck Surgery, Lower Saxony Center for Biomedical Engineering, Implant Research and Development (NIFE), Hannover Medical School, Stadtfelddamm 34, 30625 Hannover, Germany.

Postoperative restenosis in patients with external ear canal (EEC) atresia or stenosis is a common complication following canaloplasty. Our aim in this study was to explore the feasibility of using a three dimensionally (3D)-printed, patient-individualized, drug ((dexamethasone (DEX)), and ciprofloxacin (cipro))-releasing external ear canal implant (EECI) as a postoperative stent after canaloplasty. We designed and pre-clinically tested this novel implant for drug release (by high-performance liquid chromatography), biocompatibility (by the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay), bio-efficacy (by the TNF-α (tumor necrosis factor-alpha)-reduction test (DEX) and inhibition zone test (for cipro)), and microbial contamination (formation of turbidity or sediments in culture medium). Read More

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Loop-Mediated Isothermal Amplification as Point-of-Care Testing for -Mutated Lung Adenocarcinoma.

Micromachines (Basel) 2022 Jun 6;13(6). Epub 2022 Jun 6.

Department of Surgery, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku 173-8605, Tokyo, Japan.

Liquid biopsy has been adapted as a diagnostic test for mutations in patients with advanced or metastatic non-small cell lung cancer (NSCLC). Loop-mediated isothermal amplification (LAMP) has been widely used for the rapid detection of pathogens through DNA amplification. This study investigated the efficacy of an -LAMP assay using plasma samples of patients with resected NSCLC tumors. Read More

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Platelet Reactivity and Outcomes after Off-Pump Coronary Surgery in Acute Coronary Syndrome Patients.

J Clin Med 2022 Jun 8;11(12). Epub 2022 Jun 8.

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-Gu, Seoul 03722, Korea.

Ischemic and hemorrhagic complications are major determinants of survival in acute coronary syndrome (ACS) patients undergoing coronary surgery. We investigated the association of preoperative platelet reactivity to P2Y antagonists with ischemic and hemorrhagic complications after Off-Pump Coronary Artery Bypass surgery (OPCAB) in ACS patients who received dual anti-platelet therapy (DAPT) within 5 days prior to surgery. This prospective, observational study with 177 patients compared the incidence of perioperative major bleeding and major adverse cardiac events (MACEs) in relation to the tertile distribution of the % inhibitory response to P2Y antagonists, as measured by a thromboelastography platelet mapping assay. Read More

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Artificial Intelligence-Based Prediction of Oroantral Communication after Tooth Extraction Utilizing Preoperative Panoramic Radiography.

Diagnostics (Basel) 2022 Jun 6;12(6). Epub 2022 Jun 6.

Department of Oral and Maxillofacial Plastic Surgery, University Hospital of Würzburg, 97070 Würzburg, Germany.

Oroantral communication (OAC) is a common complication after tooth extraction of upper molars. Profound preoperative panoramic radiography analysis might potentially help predict OAC following tooth extraction. In this exploratory study, we evaluated n = 300 consecutive cases (100 OAC and 200 controls) and trained five machine learning algorithms (VGG16, InceptionV3, MobileNetV2, EfficientNet, and ResNet50) to predict OAC versus non-OAC (binary classification task) from the input images. Read More

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RP-Rs-fMRIomics as a Novel Imaging Analysis Strategy to Empower Diagnosis of Brain Gliomas.

Cancers (Basel) 2022 Jun 7;14(12). Epub 2022 Jun 7.

Department of Diagnostic Radiology, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.

Rs-fMRI can provide rich information about functional processes in the brain with a large array of imaging parameters and is also suitable for investigating the biological processes in cerebral gliomas. We aimed to propose an imaging analysis method of RP-Rs-fMRIomics by adopting omics analysis on rs-fMRI with exhaustive regional parameters and subsequently estimating its feasibility on the prediction diagnosis of gliomas. In this retrospective study, preoperative rs-fMRI data were acquired from patients confirmed with diffuse gliomas ( = 176). Read More

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A Radiomics Model for Preoperative Predicting Sentinel Lymph Node Metastasis in Breast Cancer Based on Dynamic Contrast-Enhanced MRI.

Front Oncol 2022 6;12:884599. Epub 2022 Jun 6.

Department of Radiology, Peking University First Hospital, Beijing, China.

Purpose: To develop a radiomics model based on preoperative dynamic contrast-enhanced MRI (DCE-MRI) to identify sentinel lymph node (SLN) metastasis in breast cancer (BC) patients.

Materials And Methods: The MRI images and clinicopathological data of 142 female primary BC patients from January 2017 to December 2018 were included in this study. The patients were randomly divided into the training and testing cohorts at a ratio of 7:3. Read More

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Language improvement after awake craniotomy in a 12-year-old child: illustrative case.

J Neurosurg Case Lessons 2022 Jun 13;3(24):CASE2293. Epub 2022 Jun 13.

Departments of Neurosurgery.

Background: Although the standard procedure to treat adult patients with lesions in eloquent brain areas is awake craniotomy with direct electrical stimulation, this procedure is not often used in children because of feasibility concerns. Some studies have shown that the procedure is feasible in children. They reported the postoperative language ability, which was not based on standardized language tests for children. Read More

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Universal tumor screening for lynch syndrome on colorectal cancer biopsies impacts surgical treatment decisions.

Fam Cancer 2022 Jun 23. Epub 2022 Jun 23.

Department of Pathology, The Ohio State University Wexner Medical Center, Optometry Clinic and Health Science Faculty Office Building, 1664 Neil Avenue, Suite 6100, Columbus, OH, 43210, USA.

Universal tumor screening (UTS) for Lynch syndrome (LS) on colorectal cancer (CRC) can be performed on biopsies or resection specimens. The advantage of biopsies is the chance to provide preoperative genetic counseling/testing (GC/T) so patients diagnosed with LS can make informed decisions regarding resection extent. We evaluated utilization of UTS on biopsies, percentage of patients with deficient mismatch repair (dMMR) who underwent GC/T preoperatively, and whether surgical/treatment decisions were impacted. Read More

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Comparison of Screening Scores for Heparin- Induced Thrombocytopenia After Cardiopulmonary Bypass.

J Cardiothorac Vasc Anesth 2022 Apr 14. Epub 2022 Apr 14.

Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC.

Objectives: To compare screening scores for heparin-induced thrombocytopenia (HIT) after cardiopulmonary bypass (CPB).

Design: Retrospective cohort study.

Setting: Cardiothoracic surgery units within a large tertiary healthcare facility from September 2010 to January 2020. Read More

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Patient Symptoms and Stress Testing After Elective Percutaneous Coronary Intervention in the Veterans Affairs Health Care System.

JAMA Netw Open 2022 Jun 1;5(6):e2217704. Epub 2022 Jun 1.

Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora.

Importance: Up to 60% of patients in the US receive a stress test within 2 years of percutaneous coronary intervention (PCI), prompting concerns about the possible overuse of stress testing.

Objective: To examine the proportion of patients who underwent stress testing within 2 years of elective PCI, proportion of patients who had symptoms that were consistent with coronary artery disease (CAD), timing of stress testing, and site-level variation in stress testing among symptomatic and asymptomatic patients.

Design, Setting, And Participants: This cohort study used administrative claims data and clinical records from the US Department of Veterans Affairs (VA) Clinical Assessment, Reporting, and Tracking program. Read More

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Peritumoral radiomics features on preoperative thin-slice CT images can predict the spread through air spaces of lung adenocarcinoma.

Sci Rep 2022 Jun 20;12(1):10323. Epub 2022 Jun 20.

Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

The spread through air spaces (STAS) is recognized as a negative prognostic factor in patients with early-stage lung adenocarcinoma. The present study aimed to develop a machine learning model for the prediction of STAS using peritumoral radiomics features extracted from preoperative CT imaging. A total of 339 patients who underwent lobectomy or limited resection for lung adenocarcinoma were included. Read More

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Increased Risk of Postoperative Mortality Associated With Prior COVID-19 Infection.

Am J Prev Med 2022 Jul;63(1S1):S75-S82

Department of Surgery, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama. Electronic address:

Introduction: The impact of COVID-19 infection on surgical patients is largely described by small-cohort studies. This study characterized the risk factors for postoperative mortality among patients with preoperative COVID-19 infection.

Methods: Data were abstracted from the electronic medical record for patients who tested positive for COVID-19 before surgery, excluding procedures related to extracorporeal membrane oxygenation (case, March 2020-April 2021). Read More

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Clinicopathologic features of thyroid nodules with PTEN mutations on preoperative testing.

Endocr Relat Cancer 2022 Jun 1. Epub 2022 Jun 1.

E Morariu, Department of Medicine, University of Pittsburgh, Pittsburgh, United States.

The incidence of cancer in thyroid nodules carrying germline or somatic PTEN mutations is not well defined. This study characterizes clinical and histopathologic features of thyroid nodules with preoperatively detected PTEN mutations and their impact on management. Thyroid nodules with PTEN mutations on molecular testing of fine needle aspirate (FNA) specimens from November 2017 to July 2020 at our institution were included. Read More

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Predictors of Positive Outcomes and a Scoring System to Guide Management After Fasciotomy for Chronic Exertional Compartment Syndrome.

Orthop J Sports Med 2022 Jun 14;10(6):23259671221101328. Epub 2022 Jun 14.

Trauma and Orthopaedic Department, Royal United Hospitals, Bath, UK.

Background: Chronic exertional compartment syndrome (CECS) of the lower limb usually responds well to fasciotomy in patients with failed nonoperative treatment. Careful history taking and compartment pressure testing are both required to accurately diagnose CECS.

Purposes: To evaluate patients with CECS after fasciotomy to establish predictive criteria of positive outcomes and to develop a scoring system to aid clinicians in their management of such patients. Read More

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Application of deep learning algorithm in automated identification of knee arthroplasty implants from plain radiographs using transfer learning models: Are algorithms better than humans?

J Orthop 2022 Jul-Aug;32:139-145. Epub 2022 May 26.

Consultant, Department of Orthopedic Surgery, Sir H N Reliance Foundation Hospital, Girgaum, Mumbai, Maharashtra, India.

Aim: In preoperative planning of a revision knee arthroplasty, it can be challenging to identify an implant manufacturer type from a primary knee arthroplasty due to the inability to identify the implants in time. It has been shown that deep learning improves diagnosis with each iteration in the medical field. The problem of identifying the manufacturer and model of knee arthroplasty prostheses has been solved using automated deep learning models. Read More

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Clinical and urodynamic findings before and after surgical repair of pelvic organ prolapse in women with lower urinary tract symptoms. A prospective observational study.

Urology 2022 Jun 14. Epub 2022 Jun 14.

Department of Urology, Ain Shams University, Cairo, Egypt. Electronic address:

Objectives: To investigate the association between urodynamic findings and lower urinary tract symptoms (LUTS) before and after surgical treatment of POP.

Methods: Seventy-four patients with stage II or more anterior POP associated with LUTS and eligible for surgical repair of POP were included in this prospective study. All cases had clinical evaluation and urodynamic testing (UDS) before and 6 months after surgical repair of POP. Read More

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[Routine screening with APTT is not indicated before surgery].

Lakartidningen 2022 Jun 17;119. Epub 2022 Jun 17.

professor, överläkare, klinisk kemi, Linköpings universitet.

Activated partial thromboplastin time (APTT) is widely practiced in preoperative screening. The value of using this test to predict the risk of perioperative bleeding is not well documented in Sweden. In this article, a literature review is performed to determine whether unselected APTT testing can predict abnormal perioperative bleeding. Read More

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A computerized diagnostic model for automatically evaluating placenta accrete spectrum disorders based on the combined MR radiomics-clinical signatures.

Sci Rep 2022 Jun 16;12(1):10130. Epub 2022 Jun 16.

Department of Radiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, People's Republic of China.

We aimed to establish a computerized diagnostic model to predict placenta accrete spectrum (PAS) disorders based on T2-weighted MR imaging. We recruited pregnant women with clinically suspected PAS disorders between January 2015 and December 2018 in our institution. All preoperative T2-weighted imaging (T2WI) MR images were manually outlined on the picture archive communication system terminal server. Read More

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[Evaluation of Functional Operability Prior to Lung Surgery].

Zentralbl Chir 2022 Jun 15;147(3):313-328. Epub 2022 Jun 15.

Klinik für Thoraxchirurgie, Florence-Nightingale-Krankenhaus, Akademisches Lehrkrankenhaus der Heinrich-Heine-Universität, Düsseldorf, Deiutschland.

Cardiac and pulmonary physiologic assessment is necessary for risk stratification before any lung resection. It may uncover hidden health issues, which can be addressed first to make patients fit for surgery. It allows for the surgeon to estimate the patient's risk for major complications and at the same time for the patient to understand the procedural risks and give informed consent or even reject surgery. Read More

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