7,994 results match your criteria Preoperative Testing

Beyond the Wada: An updated approach to pre-surgical language and memory testing: An updated review of available evaluation techniques and recommended workflow to limit Wada test use to essential clinical cases.

Epilepsy Res 2021 Aug 15;174:106673. Epub 2021 May 15.

Epilepsy Division, Department of Neurology, University of Texas Southwestern Medical Center Dallas. Electronic address:

The Intracarotid amobarbital test (IAT), also called Wada test, is considered the "gold standard" for lateralizing language dominance in the pre-surgical evaluation of patients with epilepsy. In addition, it has been further modified to assess the postoperative risk of amnesia in patients undergoing temporal lobectomy. Since then it has been utilized to lateralize language and assess pre-surgical memory function. Read More

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Toward Dynamic Risk Prediction of Outcomes After Coronary Artery Bypass Graft: Improving Risk Prediction With Intraoperative Events Using Gradient Boosting.

Circ Cardiovasc Qual Outcomes 2021 06 3;14(6):e007363. Epub 2021 Jun 3.

Center for Outcomes Research and Evaluation, Yale New Haven Hospital, CT (M.M., T.J.S.D., C.H., B.J.M., R.A.J, A.C., W.L.S., H.M.K).

Background: Intraoperative data may improve models predicting postoperative events. We evaluated the effect of incorporating intraoperative variables to the existing preoperative model on the predictive performance of the model for coronary artery bypass graft.

Methods: We analyzed 378 572 isolated coronary artery bypass graft cases performed across 1083 centers, using the national Society of Thoracic Surgeons Adult Cardiac Surgery Database between 2014 and 2016. Read More

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Perioperative Vascular Biomarker Profiling in Elective Surgery Patients Developing Postoperative Delirium: A Prospective Cohort Study.

Biomedicines 2021 May 15;9(5). Epub 2021 May 15.

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany.

Background: Postoperative delirium (POD) ranks among the most common complications in surgical patients. Blood-based biomarkers might help identify the patient at risk. This study aimed to assess how serum biomarkers with specificity for vascular and endothelial function and for inflammation are altered, prior to or following surgery in patients who subsequently develop POD. Read More

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Age, operation time and surgical approach can be used to detect incidental gallbladder carcinoma in cholecystectomy specimens from low-incidence settings.

Histopathology 2021 Oct 6;79(4):667-673. Epub 2021 Aug 6.

Department of Pathology, University of Sherbrooke, Sherbrooke, Canada.

Aims: Gallbladders resected for non-neoplastic diseases are systemically examined microscopically to rule out incidental dysplasia and carcinoma. The main aim of this study was to test whether a pre-grossing algorithm can detect incidental gallbladder carcinoma. The secondary aim was to test whether the algorithm can detect high-grade dysplasia. Read More

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October 2021

Contrast-Enhanced CT-Based Radiomics Analysis in Predicting Lymphovascular Invasion in Esophageal Squamous Cell Carcinoma.

Front Oncol 2021 14;11:644165. Epub 2021 May 14.

Department of Computed Tomography and Magnetic Resonance, Fourth Hospital of Hebei Medical University, Shijiazhuang, China.

Objectives: To develop a radiomics model based on contrast-enhanced CT (CECT) to predict the lymphovascular invasion (LVI) in esophageal squamous cell carcinoma (ESCC) and provide decision-making support for clinicians.

Patients And Methods: This retrospective study enrolled 334 patients with surgically resected and pathologically confirmed ESCC, including 96 patients with LVI and 238 patients without LVI. All enrolled patients were randomly divided into a training cohort and a testing cohort at a ratio of 7:3, with the training cohort containing 234 patients (68 patients with LVI and 166 without LVI) and the testing cohort containing 100 patients (28 patients with LVI and 72 without LVI). Read More

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Analysis of Long-Term Outcomes Following Surgical Contracture Release of the Elbow: A Case Series.

Cureus 2021 Apr 26;13(4):e14691. Epub 2021 Apr 26.

Orthopaedics, Penn State Health Milton S. Hershey Medical Center, Hershey, USA.

Background Elbow contracture is a debilitating condition with an incidence ranging from as low as almost 1% to as high as 20% and results in significant limiting consequences on a patient's activities of daily living (ADLs). Postoperative rehabilitation is important in maintaining the range of motion and sustaining an improved range of motion. The purpose of this study was to evaluate the long-term results of elbow contracture release surgery and the effect of an occupational therapy/physical therapy (OT/PT)-guided, self-directed rehabilitation program following surgery, without the use of continuous passive motion (CPM) devices. Read More

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Thyroseq v3, Afirma GSC, and microRNA Panels Versus Previous Molecular Tests in the Preoperative Diagnosis of Indeterminate Thyroid Nodules: A Systematic Review and Meta-Analysis.

Front Endocrinol (Lausanne) 2021 13;12:649522. Epub 2021 May 13.

Department of Surgery V, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Cluj-Napoca, Romania.

Background: Molecular tests are being used increasingly as an auxiliary diagnostic tool so as to avoid a diagnostic surgery approach for cytologically indeterminate thyroid nodules (ITNs). Previous test versions, Thyroseq v2 and Afirma Gene Expression Classifier (GEC), have proven shortcomings in malignancy detection performance.

Objective: This study aimed to evaluate the diagnostic performance of the established Thyroseq v3, Afirma Gene Sequencing Classifier (GSC), and microRNA-based assays versus prior iterations in ITNs, in light of "rule-in" and "rule-out" concepts. Read More

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Prevalence of Anti-HBc Antibodies among HBsAg Negative Individuals and Its Association with Occult Hepatitis B.

J Lab Physicians 2021 Mar 19;13(1):1-5. Epub 2021 May 19.

Department of Microbiology, Government TD Medical College, Alappuzha, Kerala, India.

 Hepatitis B virus (HBV) infection is an endemic in many Asian countries, and among the major routes of transmission, transfusion is the one that should be prevented. Occult HBV infection (OBI) is defined as the presence of HBV DNA in the absence of detectable HBsAg, with or without anti-HBV antibodies. The aim of this study was to detect the prevalence of anti-HBc total antibodies among the HB surface antigen (HBsAg) negative individuals by way of enzyme-linked immunosorbent assay (ELISA), and detect the presence of HBV DNA among the anti-HBc seropositives by polymerase chain reaction (PCR). Read More

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Economic Burden of Patient-Reported Penicillin Allergy on Total Hip and Total Knee Arthroplasty.

J Arthroplasty 2021 Sep 4;36(9):3067-3072. Epub 2021 May 4.

Department of Orthopaedic Surgery, Tulane University School of Medicine, New Orleans, LA.

Introduction: Self-reported penicillin allergies in patients undergoing total joint arthroplasty often results in the use of second-line prophylactic antibiotics. A higher risk of prosthetic joint infection (PJI) is associated with suboptimal antibiotics vs first generation cephalosporins, which have historically been grouped with other beta-lactam antibiotics such as penicillin for potential allergic reactions. This study evaluates the economic burden of self-reported penicillin allergies in total joint arthroplasty (TJA). Read More

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September 2021

Cataract standard set for outcome measures: An Italian tertiary referral centre experience.

Eur J Ophthalmol 2021 May 31:11206721211018370. Epub 2021 May 31.

Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain.

Purpose: Implementation of the International Consortium for Health Outcomes Measurements (ICHOM) standard for cataract surgery into clinical practice at an Italian tertiary referral centre.

Methods: Prospective, observational, descriptive study consisting of the registry and analysis of cataract surgeries performed during a 6-month enrolment period at the University Eye Clinic of Trieste, Trieste, Italy. Outcomes were recorded and analysed according to the ICHOM Cataract Standard Set version 2. Read More

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Potential for optimizing the perioperative care in robotic prostatectomy patients by adoption of enhanced recovery after surgery principles.

J Robot Surg 2021 May 29. Epub 2021 May 29.

Department of Urology and Pediatric Urology, University Clinic Mainz, Mainz, Germany.

Several benefits have been reported after applying the principles of enhanced recovery after surgery (ERAS) into the perioperative care of patients undergoing robot-assisted radical prostatectomy (RARP). Nevertheless, there are still barriers. We aimed to identify the key areas by systematically surveying urology departments in Germany and Austria. Read More

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Outcomes After Laparoscopic Cholecystectomy in Hyperkinetic Biliary Dyskinesia.

Am Surg 2021 May 28:31348211023390. Epub 2021 May 28.

Department of General Surgery, 12279Wake Forest School of Medicine, Winston Salem, NC, USA.

Background: Biliary dyskinesia (BD) is a poorly understood functional gallbladder disorder. Diagnosis is made with abdominal pain and an intact gallbladder without signs of anatomical obstruction on imaging or pathology. Our aim was to assess whether laparoscopic cholecystectomy (LC) resolves hyperkinetic BD symptoms. Read More

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Balancing task sensitivity with reliability for multimodal language assessments.

J Neurosurg 2021 May 28:1-8. Epub 2021 May 28.

1Department of Neurological Surgery, University of California, San Francisco, California; and.

Objective: Intraoperative tasks for awake language mapping are typically selected based on the language tracts that will likely be encountered during tumor resection. However, diminished attention and arousal secondary to perioperative sedatives may reduce a task's usefulness for identifying eloquent cortex. For instance, accuracy in performing select language tasks may be high preoperatively but decline in the operating room. Read More

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Efficacy of preoperative inhaled LAMA/LABA combinations in patients with lung cancer and untreated COPD.

Minerva Surg 2021 May 28. Epub 2021 May 28.

Department of General Thoracic Surgery, Center of Respiratory Disease, Gifu University Hospital, Gifu, Japan.

Background: Chronic obstructive pulmonary disease (COPD) is associated with a high incidence of postoperative pulmonary complications (PPCs). When untreated COPD is found before lung cancer surgery, we have been actively intervening therapeutically with inhaled long-acting muscarinic antagonist (LAMA)/long-acting β2-agonist (LABA) combinations. We investigated the efficacy of preoperative LAMA/LABA treatment. Read More

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The ASH-ASPHO Choosing Wisely Campaign: 5 hematologic tests and treatments to question.

Pediatr Blood Cancer 2021 Aug 28;68(8):e28967. Epub 2021 May 28.

Division of Hematology/Oncology, St. Michael's Hospital, Toronto, ON, Canada.

Choosing Wisely is a medical stewardship and quality-improvement initiative led by the American Board of Internal Medicine Foundation in collaboration with leading medical societies in the United States. The American Society of Hematology (ASH) has been an active participant in the Choosing Wisely project. In 2019, ASH and the American Society of Pediatric Hematology/Oncology (ASPHO) formed a joint task force to solicit, evaluate, and select items for a pediatric-focused Choosing Wisely list. Read More

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Expanding Hospital Capacity during the COVID-19 Pandemic: The Family Voice Matters.

Pediatr Qual Saf 2021 May-Jun;6(3):e411. Epub 2021 May 19.

Boston Children's Hospital, Boston, Mass.

During the initial COVID-19 response, this children's hospital reduced its inpatient capacity by 52 beds with double rooms' conversion to single patient occupancy, causing significant capacity constraints. To solve this challenge, the family perspective was engaged to safely redouble patient rooms and expand capacity as clinical activity increased during the COVID-19 response.

Methods: The team conducted qualitative descriptive interviews with parents of children undergoing congenital heart surgery admitted to the inpatient cardiac unit in a 404-bed free-standing children's hospital. Read More

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Synacthen Stimulation Test Following Unilateral Adrenalectomy Needs to Be Interpreted With Caution.

Front Endocrinol (Lausanne) 2021 11;12:654600. Epub 2021 May 11.

Department of Endocrinology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.

Background: Cortisol levels in response to stress are highly variable. Baseline and stimulated cortisol levels are commonly used to determine adrenal function following unilateral adrenalectomy. We report the results of synacthen stimulation testing following unilateral adrenalectomy in a tertiary referral center. Read More

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A retrospective analysis of COVID-19 diagnosis results obtained by rapid antigen tests and RT-PCR: Implications for disease management.

Indian J Med Microbiol 2021 May 24. Epub 2021 May 24.

Scientist-D, Genetic Research Centre, ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai, 400012, India. Electronic address:

There is a need for understanding and establishment of the most appropriate testing algorithm for COVID-19 diagnosis in asymptomatic high-risk groups. Here, we present a retrospective analysis of RT-PCR results obtained from 412 cases tested negative for coronavirus disease 2019 (COVID-19) by rapid antigen testing method. Among 178 (43. Read More

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Preoperative angiotensin II type 2 receptor is a predictor for developing chronic post-surgical pain after total knee arthroplasty surgery.

Life Sci 2021 Aug 24;278:119654. Epub 2021 May 24.

Department of Anesthesiology, Anhui Provincial Hospital, Anhui Medical University, Hefei, China; Department of Anesthesiology, Anhui Provincial Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (USTC), Hefei, China. Electronic address:

Objective: This study aimed to explore whether preoperative angiotensin II type 2 receptor (ATR) level in knee osteoarthritis (OA) patients was an independent risk factor for chronic post-surgical pain (CPSP) after total knee arthroplasty (TKA).

Methods: A total of 220 patients who had undergone unilateral TKA were enrolled from October 2019 to January 2020. Quantitative sensory testing (QST), PainDETECT questionnaires (PD-Q), the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC), the hospital anxiety and depression (HAD) and serum ATR were collected preoperatively. Read More

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Does Cardiopulmonary Testing Help Predict Long-Term Survival After Esophagectomy?

Ann Surg Oncol 2021 May 26. Epub 2021 May 26.

Northern Oesophagogastric Unit, Royal Victoria Infirmary, Newcastle Upon Tyne, UK.

Background: Esophagectomy is associated with a high rate of morbidity and mortality. Preoperative cardiopulmonary fitness has been correlated with outcomes of major surgery. Variables derived from cardiopulmonary exercise testing (CPET) have been associated with postoperative outcomes. Read More

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Hip Strength Before and After Arthroscopic Femoroacetabular Impingement Surgery.

Orthopedics 2021 May-Jun;44(3):148-153. Epub 2021 May 1.

Femoroacetabular impingement (FAI) and labral pathology are associated with pain, decreased function, and hip strength deficits. Existing data are in conflict regarding when hip strength normalizes following arthroscopic treatment of FAI. The objective of this study was to identify preoperative hip strength relative to the contralateral hip not undergoing surgery as well as when postoperative strength in 4 functional muscle groups normalizes following arthroscopic treatment of FAI. Read More

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Routine Postoperative Chemistry Panels Are Not Necessary for Most Total Joint Arthroplasty Patients.

J Bone Joint Surg Am 2021 Jun;103(11):968-976

Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, Pennsylvania.

Background: The routine use of traditional chemistry-7 (chem-7) laboratory tests following total joint arthroplasty (TJA) has been called into question with the advent of short-stay procedures. Our objective was to determine the incidence, risk factors, and clinical interventions associated with inpatient abnormal routine postoperative chem-7 panels.

Methods: From 2015 to 2017, 3,162 patients underwent a total of 3,721 TJA procedures, including primary total hip arthroplasty (THA) (n = 1,939; 52. Read More

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Optimizing preoperative antibiotics in patients with β-lactam allergies: A role for pharmacy.

Am J Health Syst Pharm 2021 Aug;78(Supplement_3):S76-S82

Department of Pharmacy Services, Henry Ford Hospital, Detroit, MI, USA.

Purpose: Patients with a reported β-lactam allergy (BLA) are often given alternative perioperative antibiotic prophylaxis, increasing risk of surgical site infections (SSIs), acute kidney injury (AKI), and Clostridioides difficile infection (CDI). The purpose of this study was to implement and evaluate a pharmacist-led BLA clarification interview service in the preoperative setting.

Methods: A pharmacist performed BLA clarification telephone interviews before elective procedures from November 2018 to March 2019. Read More

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Extra-articular mini-open proximal phalanx osteotomy with retrograde intramedullary headless screw under WALANT - Surgical technical.

Hand Surg Rehabil 2021 Oct 24;40(5):687-691. Epub 2021 May 24.

Dalhouisie University, Suite C204, 600 Main Street, Saint John, NB E2K 1J5, Canada. Electronic address:

We report on the surgical technique for mini-open derotation osteotomy using retrograde osteosynthesis by headless compression screw under WALANT anesthesia (video attached). Preoperative CT showed the feasibility of this technique, with a 2.2 mm headless compression screw. Read More

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October 2021

Machine Learning Algorithms Predict Prolonged Opioid Use in Opioid-Naïve Primary Hip Arthroscopy Patients.

J Am Acad Orthop Surg Glob Res Rev 2021 05 25;5(5):e21.00093-8. Epub 2021 May 25.

From the Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY (Dr. Kunze); and the Department of Orthopaedic Surgery, Division of Sports Medicine, Rush University Medical Center, Chicago, IL (Mr. Polce, Mr. Alter, and Dr. Nho).

Introduction: Excessive opioid use after orthopaedic surgery procedures remains a concern because it may result in increased morbidity and imposes a financial burden on the healthcare system. The purpose of this study was to develop machine learning algorithms to predict prolonged opioid use after hip arthroscopy in opioid-naïve patients.

Methods: A registry of consecutive hip arthroscopy patients treated by a single fellowship-trained surgeon at one large academic and three community hospitals between January 2012 and January 2017 was queried. Read More

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Effects of COVID-19 on Facial Plastic and Reconstructive Surgery Fellowship Training and Director Practices.

OTO Open 2021 Apr-Jun;5(2):2473974X211014130. Epub 2021 May 13.

Center for Advanced Facial Plastic Surgery, Beverly Hills, California, USA.

Objectives: The objectives of this study include characterizing the practice patterns and testing strategies of facial plastic and reconstructive surgery (FPRS) fellowship directors (FDs) secondary to COVID-19 and to quantify the impact of COVID-19 on FPRS fellowship training.

Study Design: Cross-sectional survey.

Setting: Online. Read More

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Machine learning for predicting preoperative red blood cell demand.

Transfus Med 2021 Aug 24;31(4):262-270. Epub 2021 May 24.

Department of Transfusion Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing, China.

Background: The paucity of accurate quantitative standards for determining the quantity of red blood cells (RBCs) needed for perioperative patients and the predominant application of the "preoperative hemoglobin + surgery type" empirical decision-making model have led to widespread RBC application problems.

Objective: The mathematical model of preoperative variables constructed by machine learning (ML) methods can help doctors decide preoperative RBC applications.

Methods: We retrospectively analysed 130 996 records of patients who received surgery in our hospital from January 2011 to June 2017. Read More

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Preoperative prediction for lauren type of gastric cancer: A radiomics nomogram analysis based on CT images and clinical features.

J Xray Sci Technol 2021 ;29(4):675-686

Department of Radiology, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu, China.

Purpose: To investigate feasibility of predicting Lauren type of gastric cancer based on CT radiomics nomogram before operation.

Materials And Methods: The clinical data and pre-treatment CT images of 300 gastric cancer patients with Lauren intestinal or diffuse type confirmed by postoperative pathology were retrospectively analyzed, who were randomly divided into training set and testing set with a ratio of 2:1. Clinical features were compared between the two Lauren types in the training set and testing set, respectively. Read More

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January 2021

Distal Pancreatic Resection with Splenectomy in the Rat: A Pancreatic Fistula Model to Investigate Postsurgical Damage?

Eur Surg Res 2021 21;62(2):97-104. Epub 2021 May 21.

Daniel Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Center of Operative Medicine, Medical University of Innsbruck, Innsbruck, Austria.

Background: Postoperative pancreatic fistula (POPF) is a major complication in pancreatic surgery and can cause considerable postoperative morbidity. Advanced surgical-technical approaches to prevent POPF did not yield a substantial improvement. To investigate innovative treatments, experimental animal models of distal pancreatic resection and pancreaticoduodenectomy are of fundamental importance. Read More

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PPE training and the effectiveness of universal masking in preventing exposures: The importance of the relationship between anesthesia and infection prevention.

Am J Infect Control 2021 10 19;49(10):1322-1323. Epub 2021 May 19.

Department of Infection Prevention, Emory University Hospital, Midtown. Atlanta, GA. Electronic address:

Early in the pandemic, infection prevention (IP), in collaboration with our local anesthesia leadership, took the approach of ensuring all members of the Anesthesia Department understood the importance of universal masking, were individually trained on the use of the Controlled Air Purifier Respirator, as well the appropriate method for donning/doffing N95 respirators. Multiple providers in the department tested positive for COVID, resulting in the IP Department to conduct the routine contact tracing investigation. During the investigation, it was determined that all persons who met the CDC (Centers for Disease Control & Prevention) contact exposure guidelines would undergo COVID testing, which consequently was 109 team members due to the exposure risk identified in the break room space. Read More

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October 2021