7,365 results match your criteria Prenatal Nutrition


Rising rates of cesarean delivery in Ecuador: Socioeconomic and institutional determinants over two decades.

Birth 2019 Feb 13. Epub 2019 Feb 13.

Department of Anthropology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Background: Ecuador's cesarean delivery rate far exceeds that recommended by the Pan American Health Organization (PAHO) and the World Health Organization (WHO). Using data from three iterations of Ecuador's nationally representative, population-based survey Encuesta Nacional de Salud y Nutrición (ENSANUT/ENDEMAIN), spanning 23 years, this study examines women's mode of delivery outcomes by sociodemographic characteristics and hospital type (private, public, social security) in light of Ecuador's major health care reform over the past two decades.

Methods: Using data from the 1994, 2004, and 2012 iterations of the data set, we analyzed trends in cesarean delivery based on province, year, and institution of care. Read More

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http://dx.doi.org/10.1111/birt.12421DOI Listing
February 2019
1 Read

No Associations Between Serum Lipid Levels or HOMA-IR and Asthma in Children and Adolescents: a NHANES Analysis

J Clin Res Pediatr Endocrinol 2019 Feb 14. Epub 2019 Feb 14.

Division of Pulmonary Medicine, Children’s Hospital of Shanghai (Jing An Branch), Shanghai Jiao Tong University, Shanghai 200040

Objective: Studies have reported inconsistent results of the associations between lipids and insulin resistance (IR) and asthma. The purpose of this study was to examine the associations between abnormal serum lipid levels and homeostatic model assessment-insulin resistance (HOMA-IR) and the presence of current asthma in children and adolescents.

Methods: The United States National Health and Nutrition Examination Survey database from 1999 to 2012 was randomly searched for children (aged 3-11 years) and adolescents (aged 12-19 years) with and without asthma and with complete demographic and clinical data of interest. Read More

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http://dx.doi.org/10.4274/jcrpe.galenos.2019.2018.0098DOI Listing
February 2019

Maternal Choline Supplementation Modulates Placental Markers of Inflammation, Angiogenesis, and Apoptosis in a Mouse Model of Placental Insufficiency.

Nutrients 2019 Feb 12;11(2). Epub 2019 Feb 12.

Division of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.

(distal-less homeobox 3) haploinsufficiency in mice has been shown to result in restricted fetal growth and placental defects. We previously showed that maternal choline supplementation (4X versus 1X choline) in the +/- mouse increased fetal and placental growth in mid-gestation. The current study sought to test the hypothesis that prenatal choline would modulate indicators of placenta function and development. Read More

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http://dx.doi.org/10.3390/nu11020374DOI Listing
February 2019

Prenatal maternal docosahexaenoic acid intake and infant information processing at 4.5mo and 9mo: A longitudinal study.

PLoS One 2019 13;14(2):e0210984. Epub 2019 Feb 13.

School of Psychological Sciences, The University of Manchester, Manchester, United Kingdom.

Previous research suggesting an association between maternal prenatal docosahexaenoic acid (DHA) intake and infant cognition has yet to assess whether there is a critical trimester for the observed effects. We used a comprehensive Food Frequency Questionnaire to estimate DHA levels during both the second and third trimesters of pregnancy, in a sample of 125 pregnant women. Infants were assessed at 4. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210984PLOS
February 2019

Factors Associated with Excessive Gestational Weight Gain Among Brazilian Mothers.

Breastfeed Med 2019 Feb 13. Epub 2019 Feb 13.

Nutrition Department, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Background: Gestational Weight Gain (GWG) is an important predictor of maternal and child health.

Materials And Methods: Cross-sectional study was carried out in a public maternity unit of a hospital in a Brazilian metropolis that aimed to evaluate the factors associated with excessive GWG. Data were collected on food consumption, anthropometry, and on socioeconomic, demographic, and health status. Read More

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http://dx.doi.org/10.1089/bfm.2018.0234DOI Listing
February 2019

Altered cord blood mitochondrial DNA content and pregnancy lead exposure in the PROGRESS cohort.

Environ Int 2019 Feb 9;125:437-444. Epub 2019 Feb 9.

Department of Environmental Health Sciences, Columbia University, Mailman School of Public Health, New York, NY, USA. Electronic address:

Introduction: Lead (Pb) crosses the placenta and can cause oxidative stress, reduced fetal growth and neurological problems. The principal source of oxidative stress in human cells is mitochondria. Therefore, disruption of normal mitochondrial function during pregnancy may represent a primary mechanism behind the adverse effects of lead. Read More

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http://dx.doi.org/10.1016/j.envint.2019.01.077DOI Listing
February 2019
6 Reads

Maternal-Infant Supplementation with Small-Quantity Lipid-Based Nutrient Supplements Does Not Affect Child Blood Pressure at 4-6 Y in Ghana: Follow-up of a Randomized Trial.

J Nutr 2019 Feb 11. Epub 2019 Feb 11.

Program in International and Community Nutrition, Department of Nutrition, University of California Davis, Davis, CA.

Background: In the International Lipid-Based Nutrient Supplements (iLiNS)-DYAD-Ghana trial, prenatal small-quantity lipid-based nutrient supplements (LNSs) had a positive effect on birth weight. Birth weight may be inversely related to blood pressure (BP) later in life.

Objectives: We examined the effect of the intervention on BP at 4-6 y of age, and maternal and child factors related to BP. Read More

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http://dx.doi.org/10.1093/jn/nxy285DOI Listing
February 2019
2 Reads

The relationship between IGF-I and -II concentrations and body composition at birth and over the first 2 months.

Pediatr Res 2019 Feb 11. Epub 2019 Feb 11.

The Irish Centre for Fetal and Neonatal Translational Research, Cork, Ireland.

Background: Insulin-like growth factor (IGF)-I and -II play an important role in prenatal growth. During the first 2 months from birth, body fat doubles, and rapid weight gain during this time increases future risk of cardiometabolic disease.

Objective: To determine whether IGF measurements at birth associate with body composition and the trajectory of its changes in the first 2 months. Read More

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http://dx.doi.org/10.1038/s41390-019-0331-xDOI Listing
February 2019

Risk and Protective Environmental Factors Associated with Autism Spectrum Disorder: Evidence-Based Principles and Recommendations.

J Clin Med 2019 Feb 8;8(2). Epub 2019 Feb 8.

Child Neurology and Psychiatry Unit, Systems Medicine Department, Tor Vergata University of Rome, 00133 Rome, Italy.

Autism Spectrum Disorder (ASD) is a complex condition with early childhood onset, characterized by a set of common behavioral features. The etiology of ASD is not yet fully understood; however, it reflects the interaction between genetics and environment. While genetics is now a well-established risk factor, several data support a contribution of the environment as well. Read More

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http://dx.doi.org/10.3390/jcm8020217DOI Listing
February 2019
1 Read

Social Determinants of Gestational Weight Gain in an Obese, Low-Income Population.

Am J Perinatol 2019 Feb 11. Epub 2019 Feb 11.

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.

Objective:  To examine how social support factors affect compliance with gestational weight gain (GWG) recommendations in an obese, low-income, predominantly minority population.

Study Design:  A retrospective cohort of 772 pregnant women with body mass index > 30 was reviewed. Univariate and multinomial logistic regression analyses were used to compare GWG with pregnancy planning, relationship status, participation in group prenatal care, nutritional education, and demographic factors. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1678606
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http://dx.doi.org/10.1055/s-0039-1678606DOI Listing
February 2019
8 Reads

Evaluation and Lessons Learned From the Development and Implementation of an Online Prenatal Nutrition Training for EFNEP Paraprofessionals.

J Nutr Educ Behav 2019 Feb 5. Epub 2019 Feb 5.

Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO.

Objective: Design, implement, and evaluate the effectiveness of a video-based online training addressing prenatal nutrition for paraprofessional peer educators.

Methods: Quasi-experimental pre-posttest study with 2 groups of paraprofessionals working for the Expanded Food and Nutrition Education Program in 17 states and US territories: intervention (n = 67) and delayed intervention comparison group (n = 64). An online training was systematically developed using Smith and Ragan's instructional design model, the Cognitive Theory of Multimedia Learning, principles of adult learning, and selected constructs of the Social Cognitive Theory. Read More

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http://dx.doi.org/10.1016/j.jneb.2018.11.013DOI Listing
February 2019

Prenatal Nutrition in Team-Based Care: Current Practices and Opportunities for Optimization of Care.

Can J Diet Pract Res 2019 02 7:1-8. Epub 2019 Feb 7.

Department of Family Relations and Applied Nutrition, University of Guelph, Guelph, ON.

Purpose: To describe prenatal nutrition care currently delivered by Family Health Teams (FHTs) and Community Health Centres (CHCs) in Ontario, from the perspectives of health care providers, and to identify opportunities for improving care.

Methods: Ten 1-hour, interdisciplinary focus groups were conducted in FHTs and CHCs, involving a total of 73 health care providers. Focus groups ranged in size from 3 to 11 team members, and at least 3 different professions participated in each group. Read More

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http://dx.doi.org/10.3148/cjdpr-2018-043DOI Listing
February 2019
1 Read

Prenatal and postnatal lipid-based nutrient supplementation and cognitive, social-emotional, and motor function in preschool-aged children in Ghana: a follow-up of a randomized controlled trial.

Am J Clin Nutr 2019 Feb;109(2):322-334

Program in International and Community Nutrition, Department of Nutrition, University of California, Davis, CA.

Background: Adequate nutrition is necessary for brain development during pregnancy and infancy. Few randomized controlled trials of supplementation during these periods have measured later developmental outcomes.

Objective: Our objective was to investigate the effects of provision of prenatal and postnatal lipid-based nutrient supplements (LNS) on child development at preschool age. Read More

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http://dx.doi.org/10.1093/ajcn/nqy303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367954PMC
February 2019

Early postnatal environmental enrichment restores neurochemical and functional plasticities of the cerebral cortex and improves learning performance in hidden-prenatally-malnourished young-adult rats.

Behav Brain Res 2019 Feb 2;363:182-190. Epub 2019 Feb 2.

School of Medicine, Faculty of Medical Sciences, University of Santiago de Chile, Santiago, Chile. Electronic address:

Moderate reduction of dietary protein (from 25% to 8% casein) in pregnant rats, calorically compensated by carbohydrates, gives rise to 'hidden prenatal malnutrition' (HPM) in the offspring since it does not alter body and brain weights of pups at birth. However, this dietary treatment leads to decreased β-adrenoceptor signaling and brain derived neurotrophic factor (BDNF) levels in the pup' brain, altogether with defective cortical long-term potentiation (LTP) and lowered visuospatial memory performance. Since early postnatal environmental enrichment (EE) has been shown to exert plastic effects on the developing brain and neuroprotection both on cognition and on structural properties of the neocortex, in the present study we addressed the question of whether early postnatal EE during the lactation period could exert compensatory changes in the expression of ®-adrenergic receptors and BDNF in the neocortex of HPM rats, and if these effects are associated with an improvement or even a restore of both neocortical LTP in vivo and cognitive performance induced by HPM. Read More

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http://dx.doi.org/10.1016/j.bbr.2019.02.001DOI Listing
February 2019
2 Reads

Prenatal Metal Concentrations and Childhood Cardiometabolic Risk Using Bayesian Kernel Machine Regression to Assess Mixture and Interaction Effects.

Epidemiology 2019 03;30(2):263-273

Center for Research on Nutrition and Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico.

Background: Trace metal concentrations may affect cardiometabolic risk, but the role of prenatal exposure is unclear. We examined (1) the relation between blood metal concentrations during pregnancy and child cardiometabolic risk factors; (2) overall effects of metals mixture (essential vs. nonessential); and (3) interactions between metals. Read More

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http://dx.doi.org/10.1097/EDE.0000000000000962DOI Listing
March 2019
2 Reads

Relation between adaptive function and IQ among youth with histories of heavy prenatal alcohol exposure.

Birth Defects Res 2019 Feb 4. Epub 2019 Feb 4.

Center for Behavioral Teratology and Department of Psychology, San Diego State University, San Diego, California.

Background: Adaptive function and general intellectual function are two important and often correlated domains. While youth with prenatal alcohol exposure frequently demonstrate impairments in both domains, it is not clear whether the relation between these domains is consistent across levels of ability or whether, for example, adaptive function is less affected by intellectual function at higher ability levels. The aim of the current study was to test this relation in youth with and without prenatal alcohol exposure. Read More

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http://dx.doi.org/10.1002/bdr2.1463DOI Listing
February 2019
1 Read

Obstetric management of women with opioid use disorder.

Semin Perinatol 2019 Jan 14. Epub 2019 Jan 14.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University Hospital, 833 Chestnut Street, Philadelphia, PA, United States.

Pregnancy presents a window of opportunity for effecting positive change in the lives of women with opioid use disorder (OUD). Care should be empathetic and nonjudgmental with a focus on counseling for initiation and maintenance of beneficial health behaviors as well as development of a strong patient-provider relationship. These include adherence to treatment of OUD through pharmacotherapy and behavioral counseling, smoking cessation, healthy nutrition, treatment of coexisting medical and psychosocial conditions, as well as preparation for the postpartum period through breastfeeding education and antenatal discussion of contraception. Read More

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http://dx.doi.org/10.1053/j.semperi.2019.01.006DOI Listing
January 2019
1 Read

Association between prenatal exposure to multiple persistent organic pollutants (POPs) and growth indicators in newborns.

Environ Res 2018 Dec 30;171:285-292. Epub 2018 Dec 30.

Toxicology Unit, Research Institute of Biomedical and Health Sciences (IUIBS), Universidad de Las Palmas de Gran Canaria, Paseo Blas Cabrera s/n, 35016 Las Palmas de Gran Canaria, Spain; Spanish Biomedical Research Center in Physiopathology of Obesity and Nutrition (CIBERObn), Spain.

Despite the fact that many of persistent organic pollutants (POPs) have been banned for decades, they still constitute a group of harmful substances to human health. Prenatal exposure can have adverse effects on one's health as well as on their newborns. The present cross-sectional study, which includes 87% of the births registered in La Palma Island (Canary Islands, Spain) during 2016 (n = 447), aims to evaluate the potential adverse health effects exerted by a wide range of POPs on newborns. Read More

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http://dx.doi.org/10.1016/j.envres.2018.12.064DOI Listing
December 2018

Prenatal exposure to perfluoroalkyl substances is associated with lower hand, foot and mouth disease viruses antibody response in infancy: Findings from the Guangzhou Birth Cohort Study.

Sci Total Environ 2019 Jan 26;663:60-67. Epub 2019 Jan 26.

Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Preventive Medicine, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. Electronic address:

Background: Perfluoroalkyl substances (PFASs) are synthetic chemicals widely used in industry and for commercial products. Their immunomodulatory effects are a growing health concern in children. Hand, Foot and Mouth Disease (HFMD) is a common childhood viral infection, and increased incidence of which has parallel the rise in PFAS exposure in the Asia-Pacific region. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.01.325DOI Listing
January 2019
1 Read

Do Prenatal Exposures Pose a Real Threat to Ovarian Function? BPA as a Case Study.

Reproduction 2019 Jan 1. Epub 2019 Jan 1.

S Mahalingaiah, Department of Obstetrics and Gynecology, Boston Medical Center/Boston University School of Medicine, Boston, United States.

Fetal development represents a time of potential vulnerability due to rapid cell division, organ development, and limited fetal kidney/liver activity for detoxification and metabolism of exposures. Health effects of prenatal toxicant exposure have previously been described, but there is little cohesive evidence surrounding effects on ovarian function. Using bisphenol A (BPA) as a case study, we seek to examine whether a prominent prenatal environmental exposure can pose a real threat to human ovarian function. Read More

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http://dx.doi.org/10.1530/REP-17-0734DOI Listing
January 2019

Developmental Origins of Disease: Emerging Prenatal Risk Factors and Future Disease Risk.

Curr Epidemiol Rep 2018 Sep 13;5(3):293-302. Epub 2018 Jul 13.

Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.

Purpose Of Review: Many of the diseases and dysfunctions described in the paradigm of the developmental origins of health and disease have been studied in relation to prenatal nutrition or environmental toxicant exposures. Here, we selectively review the current research on four exposures-two nutritional and two environmental-that have recently emerged as prenatal risk factors for long-term health outcomes.

Recent Findings: Recent studies have provided strong evidence that prenatal exposure to (1) excessive intake of sugar-sweetened beverages, (2) unhealthy dietary patterns, (3) perfluoroalkyl substances, and (4) fine particulate matter, may increase risk of adverse health outcomes, such as obesity, cardiometabolic dysfunction, and allergy/asthma. Read More

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http://dx.doi.org/10.1007/s40471-018-0161-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345523PMC
September 2018

Vitamin D status during pregnancy and offspring outcomes: a systematic review and meta-analysis of observational studies.

Eur J Clin Nutr 2019 Jan 25. Epub 2019 Jan 25.

Research Group in Nutrition and Mental Health (NUTRISAM), Nutrition and Public Health Unit, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain.

Background/objectives: Vitamin D deficiency during pregnancy may influence adverse outcomes in offspring. The aim of this systematic review and meta-analysis of observational studies was to assess the association between low prenatal concentrations of 25(OH)D (by using three different cut-off levels), preterm birth (PTB) and anthropometric and neurodevelopmental outcomes in offspring.

Subjects/methods: Studies reporting data on the association between maternal vitamin D concentrations and offspring outcomes identified through a systematic review of scientific literature published in PubMed/MEDLINE, Scopus and the Cochrane Library databases up to April 2017. Read More

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http://dx.doi.org/10.1038/s41430-018-0373-xDOI Listing
January 2019
1 Read

Trimester-Specific Assessment of Diet Quality in a Sample of Canadian Pregnant Women.

Int J Environ Res Public Health 2019 Jan 24;16(3). Epub 2019 Jan 24.

School of Nutrition, Laval University, Quebec City, QC G1V 0A6, Canada.

The present study aimed to (1) examine changes in diet quality throughout pregnancy and (2) identify maternal characteristics associated with trimester-specific diet quality. Pregnant women ( = 79) were recruited in their 1st trimester of pregnancy and completed, at each trimester, three web-based 24-hour dietary recalls, from which the Canadian Healthy Eating Index (HEI) was calculated. Physical activity, nutrition knowledge, and socio-demographic web-questionnaires were also completed. Read More

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http://dx.doi.org/10.3390/ijerph16030311DOI Listing
January 2019

Nerve Growth Factor Levels in Term Human Infants: Relationship to Prenatal Growth and Early Postnatal Feeding.

Int J Endocrinol 2018 23;2018:7562702. Epub 2018 Dec 23.

Institut de Recerca Pediàtrica Hospital Sant Joan de Déu (IRP-HSJD), University of Barcelona, 08950 Esplugues, Barcelona, Spain.

Background: Nerve growth factor (NGF) plays a key role in neuroprotection and developmental maturity. We assessed longitudinally the circulating concentrations of NGF in term healthy human newborns and infants as well as their association with prenatal growth and early postnatal feeding patterns.

Methods: Circulating NGF and anthropometric measures (weight, length, body mass index, and ponderal index) were assessed longitudinally-at birth and at age 4 months-in 86 term infants born appropriate (AGA), small (SGA), or large for gestational age (LGA). Read More

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http://dx.doi.org/10.1155/2018/7562702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323468PMC
December 2018
1 Read

Effect of maternal pre-pregnancy BMI and weekly gestational weight gain on the development of infants.

Nutr J 2019 01 23;18(1). Epub 2019 Jan 23.

Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.

Objective: The aim of the present study is to identify the average effect across different time points and to specify the time effects of maternal pre-pregnancy BMI and weekly gestational weight gain on the mental development and physical growth of infants.

Methods: The present cohort study used a repeated measures study design that began in 2004 with follow up at 3, 6, 12, 18, and 24 months of age. The participants were a subset from a controlled, cluster-randomized, double-blind trial. Read More

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http://dx.doi.org/10.1186/s12937-019-0432-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345052PMC
January 2019
1 Read

Prenatal Exposure to Traffic Pollution and Childhood Body Mass Index Trajectory.

Front Endocrinol (Lausanne) 2018 7;9:771. Epub 2019 Jan 7.

Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, United States.

Limited evidence suggests an association between prenatal exposure to traffic pollution and greater adiposity in childhood, but the time window during which growth may be most affected is not known. We studied 1,649 children in Project Viva, a Boston-area pre-birth cohort. We used spatiotemporal models to estimate prenatal residential air pollution exposures and geographic information systems to estimate neighborhood traffic density and roadway proximity. Read More

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https://www.frontiersin.org/article/10.3389/fendo.2018.00771
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http://dx.doi.org/10.3389/fendo.2018.00771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330299PMC
January 2019
3 Reads

Obesity programmed by prenatal dexamethasone and postnatal high-fat diet leads to distinct alterations in nutrition sensory signals and circadian-clock genes in visceral adipose tissue.

Lipids Health Dis 2019 Jan 18;18(1):19. Epub 2019 Jan 18.

Graduate Institute of Clinical Medicine, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan.

Background: Prenatal dexamethasone treatment has been shown to enhance the susceptibility of offspring to postnatal high-fat (HF) diet-induced programmed obesity. We investigated the metabolic phenotypes, nutrient-sensing signal and circadian-clock genes in adipose tissue that are programmed by prenatal dexamethasone exposure and postnatal HF diet.

Methods: Male offspring of Sprague-Dawley rats were divided into four experimental groups: normal diet, prenatal dexamethasone exposure, postnatal HF diet, and prenatal dexamethasone plus postnatal HF diet. Read More

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http://dx.doi.org/10.1186/s12944-019-0963-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339284PMC
January 2019
1 Read
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Smoking cessation during pregnancy: a population-based study.

Rev Saude Publica 2018 Dec 20;53:03. Epub 2018 Dec 20.

Universidade Federal de Pelotas. Faculdade de Medicina. Departamento de Medicina Social. Programa de Pós-Graduação em Epidemiología. Pelotas, RS, Brasil.

Objective: To measure the prevalence of smoking cessation during pregnancy and to identify factors associated with its occurrence.

Methods: The present survey included all puerperal women living in the municipality of Rio Grande, RS, whose birth occurred between January 1 and December 31, 2013. A single standardized questionnaire was applied, in the hospital, within 48 hours of delivery. Read More

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http://dx.doi.org/10.11606/S1518-8787.2019053000619DOI Listing
December 2018
8 Reads

Effect of prenatal calcium supplementation on bone during pregnancy and 1 y postpartum.

Am J Clin Nutr 2019 Jan;109(1):197-206

Children's Hospital Oakland Research Institute, Oakland, CA.

Background: Low calcium intake during pregnancy may cause maternal skeletal calcium mobilization to meet fetal needs. The Recommended Dietary Allowance (RDA) for calcium in nonpregnant, pregnant, or lactating women aged 19-50 y is 1000 mg/d; most women in the United States report consuming 60-80% of the calcium RDA. An insufficient calcium intake could increase maternal bone loss during pregnancy and reduce bone recovery postpartum. Read More

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https://academic.oup.com/ajcn/advance-article/doi/10.1093/aj
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http://dx.doi.org/10.1093/ajcn/nqy233DOI Listing
January 2019
10 Reads

Comparing outcomes of nutrition therapy, insulin and oral anti-diabetics in managing diabetes mellitus in Pregnancy: Retrospective study and review of current guidelines.

Diabetes Metab Syndr 2019 Jan - Feb;13(1):104-109. Epub 2018 Aug 24.

Faculty of Medicine, Tarumanagara University Jl. Letjen S. Parman No.1, Jakarta, Indonesia. Electronic address:

Aims: This study aims to evaluate the glycemic profile and outcomes of Indonesian diabetic pregnant mothers based on their methods of therapy and review current international as well as national guidelines on management of diabetes in pregnancy.

Materials And Methods: Data was obtained from medical records of Hermina-Podomoro Hospital. Subjects were grouped based on therapy - nutrition therapy only, insulin and oral anti-diabetics group. Read More

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http://dx.doi.org/10.1016/j.dsx.2018.08.024DOI Listing
August 2018
1 Read

Effects of a lifestyle intervention during pregnancy to prevent excessive gestational weight gain in routine care - the cluster-randomised GeliS trial.

BMC Med 2019 Jan 14;17(1). Epub 2019 Jan 14.

Else Kröner-Fresenius-Centre for Nutritional Medicine, Klinikum rechts der Isar, Technical University of Munich, Georg-Brauchle-Ring 62, 80992, Munich, Germany.

Background: Excessive gestational weight gain (GWG) leads to obstetric complications, maternal postpartum weight retention and an increased risk of offspring obesity. The GeliS study examines the effect of a lifestyle intervention during pregnancy on the proportion of women with excessive GWG and pregnancy and obstetric complications, as well as the long-term risk of maternal and infant obesity.

Methods: The GeliS study is a cluster-randomised multicentre controlled trial including 2286 women with a pre-pregnancy BMI between 18. Read More

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http://dx.doi.org/10.1186/s12916-018-1235-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330753PMC
January 2019
2 Reads

Male and Female Intrauterine Growth-Restricted Offspring Differ in Blood Pressure, Renal Function, and Glucose Homeostasis Responses to a Postnatal Diet High in Fat and Sugar.

Hypertension 2019 Mar;73(3):620-629

From the Department of Physiology and Biophysics (S.I., J.H.D., J.M.J., A.D.B., B.T.A.), University of Mississippi Medical Center, Jackson.

It is well established that inadequate nutrition during fetal life followed by postnatal overabundance programs adiposity and glucose intolerance. Studies addressing sexual dimorphism in developmental responses to a dietary mismatch are limited; the effect on blood pressure and renal function is understudied. Therefore, this study tested the hypothesis that a mismatch of prenatal and postnatal nutrition heightens cardiorenal and metabolic risk, outcomes that may vary by sex. Read More

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374157PMC
March 2019
1 Read

Inflammatory bowel disease and new-onset psychiatric disorders in pregnancy and post partum: a population-based cohort study.

Gut 2019 Jan 9. Epub 2019 Jan 9.

ICES, Toronto, Ontario, Canada.

Objective: Patients with inflammatory bowel disease (IBD) have an elevated risk of mental illness. We determined the incidence and correlates of new-onset mental illness associated with IBD during pregnancy and post partum.

Design: This cohort study using population-based health administrative data included all women with a singleton live birth in Ontario, Canada (2002-2014). Read More

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2018-317610
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http://dx.doi.org/10.1136/gutjnl-2018-317610DOI Listing
January 2019
5 Reads

Prenatal Iron Deficiency and Replete Iron Status Are Associated with Adverse Birth Outcomes, but Associations Differ in Ghana and Malawi.

J Nutr 2019 Jan 9. Epub 2019 Jan 9.

Program in International and Community Nutrition, Department of Nutrition.

Background: Previous literature suggests a U-shaped relation between hemoglobin concentration and adverse birth outcomes. There is less evidence on associations between iron status and birth outcomes.

Objective: Our objective was to determine the associations of maternal hemoglobin concentration and iron status with birth outcomes. Read More

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https://academic.oup.com/jn/advance-article/doi/10.1093/jn/n
Publisher Site
http://dx.doi.org/10.1093/jn/nxy278DOI Listing
January 2019
7 Reads

Congenital Portosystemic Shunts: Current Diagnosis and Management.

J Pediatr Gastroenterol Nutr 2019 Jan 4. Epub 2019 Jan 4.

Emmanuel Gonzales, Pediatric Hepatology and Liver Transplantation Unit, Hôpital Bicêtre, Reference Centre for Pediatric Liver Diseases-DHU Hepatinov, Assistance Publique-Hôpitaux de Paris and INSERM UMR-S 1174, Université Paris-Sud 11, Le Kremlin-Bicêtre.

Congenital porto-systemic shunts are increasingly recognized in several settings and at any age. The following are some of the most common presentations: prenatal ultrasound, neonatal cholestasis, incidental finding on abdominal imaging, or systemic complications such as unexplained cardiopulmonary or neurological disease, or the presence of liver nodules in a non-cirrhotic liver. The purpose of the present review is to summarize clinical presentation and current recommendations for management, and highlight areas of future research. Read More

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http://dx.doi.org/10.1097/MPG.0000000000002263DOI Listing
January 2019
12 Reads

Malnutrition and depression in pregnancy and associations with child behaviour and cognitive function: a review of recent evidence on unique and joint effects .

Can J Physiol Pharmacol 2019 Jan 9:1-16. Epub 2019 Jan 9.

a Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam UMC, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands.

Accumulating studies suggest that prenatal experiences can shape a child's neurodevelopment. Malnutrition and depression occur in pregnancy relatively often and may affect child neurodevelopment independently as well as synergistically. We aimed to provide an overview of recent studies that have examined malnutrition and (or) depression in pregnancy and associations with child behavioural problems and cognitive function. Read More

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http://www.nrcresearchpress.com/doi/10.1139/cjpp-2018-0381
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http://dx.doi.org/10.1139/cjpp-2018-0381DOI Listing
January 2019
5 Reads

Associations of prenatal exposure to impaired glucose tolerance with eating in the absence of hunger in early adolescence.

Int J Obes (Lond) 2019 Jan 8. Epub 2019 Jan 8.

Division of Chronic Disease Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.

Objective: Exposure to impaired gestational glucose tolerance has been shown to have sex-specific associations with offspring obesity risk, perhaps by affecting the development of appetite regulation. We examined the extent to which prenatal exposure to impaired glucose tolerance was associated with eating in the absence of hunger (EAH) in early adolescent offspring, and in turn, whether EAH was cross-sectionally associated with body composition.

Methods: We included data from 1097 adolescents participating in Project Viva, a pre-birth longitudinal cohort. Read More

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http://www.nature.com/articles/s41366-018-0296-6
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http://dx.doi.org/10.1038/s41366-018-0296-6DOI Listing
January 2019
7 Reads

Omega-3 Fatty Acid Supplementation, Pro-Resolving Mediators, and Clinical Outcomes in Maternal-Infant Pairs.

Nutrients 2019 Jan 5;11(1). Epub 2019 Jan 5.

Medical Nutrition Education Division, College of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE 68198-4045, USA.

Omega (n)-3 fatty acids are vital to neonatal maturation, and recent investigations reveal n-3 fatty acids serve as substrates for the biosynthesis of specialized pro-resolving lipid mediators (SPM) that have anti-inflammatory and immune-stimulating effects. The role SPM play in the protection against negative maternal-fetal health outcomes is unclear, and there are no current biomarkers of n-3 fatty acid sufficiency. We sought to ascertain the relationships between n-3 fatty acid intake, SPM levels, and maternal-fetal health outcomes. Read More

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http://www.mdpi.com/2072-6643/11/1/98
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http://dx.doi.org/10.3390/nu11010098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356980PMC
January 2019
4 Reads

Maternal High-Protein Diet during Pregnancy Modifies Rat Offspring Body Weight and Insulin Signalling but Not Macronutrient Preference in Adulthood.

Nutrients 2019 Jan 5;11(1). Epub 2019 Jan 5.

UMR PNCA, AgroParisTech, INRA, Université Paris-Saclay, 75005 Paris, France.

Diet of mothers during gestation may impact offspring phenotype. This study evaluated the consequences of a maternal High-Protein (HP) diet during gestation on food preferences and phenotypic characteristics in adult rat offspring. Dams were fed a HP or a Normal-Protein (NP) isocaloric diet during gestation only. Read More

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http://www.mdpi.com/2072-6643/11/1/96
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http://dx.doi.org/10.3390/nu11010096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356951PMC
January 2019
6 Reads

Prenatal Irradiation-Induced Hippocampal Abnormalities in Rats Evaluated Using Manganese-Enhanced MRI.

Front Neural Circuits 2018 17;12:112. Epub 2018 Dec 17.

Group of Quantum-State Controlled MRI, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

The aim of this study was to characterize hippocampal abnormalities in rats after prenatal x-ray irradiation using manganese-enhanced MRI (MEMRI). All radiation-exposed rat brains showed a reduced volume with prominent dilatation of lateral ventricles. Moreover, MEMRI-enhanced areas within the hippocampus were reduced in volumes by approximately 25% of controls, although the entire volume of hippocampus was decreased by approximately 50% of controls. Read More

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http://dx.doi.org/10.3389/fncir.2018.00112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304475PMC
December 2018

Supporting healthy pregnancies: Examining variations in nutrition, weight management and substance abuse advice provision by prenatal care providers in Alberta, Canada. A study using the All Our Families cohort.

PLoS One 2019 7;14(1):e0210290. Epub 2019 Jan 7.

The School of Public Policy, University of Calgary, Calgary, Alberta, Canada.

Background: Pregnancy is a critical time for fetal development, and education of women regarding healthy lifestyle choices is an important function for prenatal care providers, those that provide care to women during pregnancy. Within Canada, women choose to receive pregnancy care from one of a variety of publicly funded care providers. This study examines the association between the type of care provider(s) seen during pregnancy and the provision of advice related to nutrition, weight management and substance abuse. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210290PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322767PMC
January 2019

Factors associated with adherence to iron folate supplementation among pregnant women in West Dembia district, northwest Ethiopia: a cross sectional study.

BMC Res Notes 2019 Jan 6;12(1). Epub 2019 Jan 6.

Department of Human Nutrition, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, P.o.box.196, Gondar, Ethiopia.

Objective: In Ethiopia, iron folate tablets are prescribed for all pregnant mothers during their antenatal visits and given for free; however, only limited data are available on their adherence. Therefore, the aim of this study was to assess adherence to iron folate supplementation and its associated factors among pregnant women in West Dembia district, northwest Ethiopia. An institution based cross-sectional study was conducted on 348 pregnant women that had at least one antenatal care visit. Read More

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https://bmcresnotes.biomedcentral.com/articles/10.1186/s1310
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http://dx.doi.org/10.1186/s13104-019-4045-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322306PMC
January 2019
8 Reads

Ultra-processed Food Consumption by Pregnant Women: The Effect of an Educational Intervention with Health Professionals.

Matern Child Health J 2019 Jan 4. Epub 2019 Jan 4.

Departamento de Saúde Pública, Botucatu Medical School - São Paulo State University (UNESP), Avenida Professor Montenegro, Distrito de Rubião Júnior, s/n., Botucatu, SP, 18.618-970, Brazil.

Objectives Nutrition during pregnancy is related with many maternal and child outcomes. To investigate the consumption of ultra-processed foods is one of the newest methods to evaluate food consumption, but these studies in pregnant women are rare. Methods We conducted a non-randomized controlled educational intervention on healthy eating and physical activity during pregnancy in primary health care units of Botucatu, São Paulo, Brazil. Read More

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http://link.springer.com/10.1007/s10995-018-2690-z
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http://dx.doi.org/10.1007/s10995-018-2690-zDOI Listing
January 2019
11 Reads

A High Adherence to Six Food Targets of the Mediterranean Diet in the Late First Trimester is Associated with a Reduction in the Risk of Materno-Foetal Outcomes: The St. Carlos Gestational Diabetes Mellitus Prevention Study.

Nutrients 2018 Dec 31;11(1). Epub 2018 Dec 31.

Endocrinology and Nutrition Department, Hospital Clínico San Carlos and Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.

A prenatal diet affects materno-foetal outcomes. This is a post hoc analysis of the St. Carlos gestational diabetes mellitus (GDM) Prevention Study. Read More

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http://dx.doi.org/10.3390/nu11010066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356317PMC
December 2018
3 Reads

A Feasibility Study to Promote Optimal Weight in First Time Pregnant Mothers and Their Babies: Lessons Learned in a US-Mexico Border Community.

Matern Child Health J 2019 Jan 2. Epub 2019 Jan 2.

Department of Pediatrics, University of California-San Diego, 9500 Gilman Drive, MC 0927, La Jolla, CA, 92093-0927, USA.

Introduction Obesity rates among US Hispanic women and children are high. Childhood obesity prevention beginning prenatally is desirable, but studies show mixed results. Methods We tested a pilot intervention to promote optimal gestational and infant weight with primigravid Hispanic women at a Federally Qualified Health Center (FQHC) on the U. Read More

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http://dx.doi.org/10.1007/s10995-018-2685-9DOI Listing
January 2019

Maternal Metabolic Complications in Pregnancy and Offspring Behavior Problems at 2 Years of Age.

Matern Child Health J 2019 Jan 2. Epub 2019 Jan 2.

Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.

Objectives Prenatal maternal metabolic problems such as pre-pregnancy adiposity, excess gestational weight gain, and gestational diabetes mellitus (GDM) are associated with an increased risk of psychopathology in offspring. We examined whether these exposures were linked to symptoms of emotional and behavioral problems in offspring at 2 years of age, or if associations were due to confounding variables. Methods Data from 815 mother-child pairs enrolled at the Edmonton site of the Canadian Healthy Infant Longitudinal Development cohort were used to examine associations between gestational metabolic complications and scores on the externalizing and internalizing scales of the Child Behavior Checklist (CBCL-1½ to 5) at age two. Read More

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http://dx.doi.org/10.1007/s10995-018-2691-yDOI Listing
January 2019
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Liver transcriptomic and proteomic profiles of preweaning lambs are modified by milk replacer restriction.

J Dairy Sci 2019 Feb 26;102(2):1194-1204. Epub 2018 Dec 26.

Instituto de Ganadería de Montaña, CSIC-Universidad de León, Finca Marzanas, E-24346 Grulleros, León, Spain. Electronic address:

Prenatal and early postnatal nutrition may promote long-term effects on both feed efficiency and health of animals. Therefore, moderated milk replacer restriction during the artificial rearing period might negatively affect feed efficiency during the postweaning phases in dairy ewes. The aim of this work was to identify differentially expressed (DE) genes by RNA sequencing and differentially accumulated proteins using MALDI-TOF mass spectrometry in the liver of artificially reared Assaf lambs to identify modified metabolic pathways as a consequence of milk replacer restriction in order to find possible solutions to correct any detrimental effect caused by this factor. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00220302183112
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http://dx.doi.org/10.3168/jds.2018-15110DOI Listing
February 2019
5 Reads

[Association of dietary energy intake and energy density with gestational weight gain in Chengdu City].

Wei Sheng Yan Jiu 2018 Nov;47(6):906-912

Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu 610041, China.

Objective: To determine the association of dietary energy intake and energy density( ED) with gestational weight gain among pregnant women in Chengdu.

Methods: A total of 503 pregnant women who took the prenatal examination in West China Second University Hospital were selected in the prospective study in 2015. ED, computed as the ratio of energy intake( kcal) per weight( g) of foods( kcal/g), was calculated using three methods as follows:( 1) ED1 included foods only, excluding all beverages;( 2) ED2 included foods and milk;( 3) ED3 included foods and beverages. Read More

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November 2018
5 Reads