7,480 results match your criteria Prenatal Nutrition


The Kansas University DHA Outcomes Study (KUDOS) clinical trial: long-term behavioral follow-up of the effects of prenatal DHA supplementation.

Am J Clin Nutr 2019 Apr 20. Epub 2019 Apr 20.

Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City, KS.

Background: Docosahexaenoic acid (DHA) is a long-chain polyunsaturated fatty acid that has been linked to improved vision and cognition in postnatal feeding studies and has been consistently associated with reduction of early preterm birth in prenatal supplementation trials. This is a report of the first long-term follow-up of infants from mothers receiving prenatal DHA supplementation in a US cohort.

Objective: Our objective was to evaluate the efficacy of the prenatal supplementation on both global and granular longitudinal assessments of cognitive and behavioral development. Read More

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https://academic.oup.com/ajcn/advance-article/doi/10.1093/aj
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http://dx.doi.org/10.1093/ajcn/nqz018DOI Listing
April 2019
1 Read

Economic evaluation of California prenatal participation in the special supplemental nutrition program for Women, Infants and Children (WIC) to prevent preterm birth.

Prev Med 2019 Apr 15. Epub 2019 Apr 15.

Research and Evaluation Unit, Public Health Foundation Enterprises- Special Supplemental Nutrition Program for Women, Infants and Children (PHFE WIC), 12781 Schabarum Ave., Irwindale, CA 91706.

There is growing evidence that prenatal participation in the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) reduces the risk of adverse birth outcomes. With recent changes in health care, rising health care costs, and increasing rates of prematurity in the U.S. Read More

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http://dx.doi.org/10.1016/j.ypmed.2019.04.011DOI Listing

Aberrant DNA methylation as a diagnostic biomarker of diabetic embryopathy.

Genet Med 2019 Apr 17. Epub 2019 Apr 17.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

Purpose: Maternal diabetes is a known teratogen that can cause a wide spectrum of birth defects, collectively referred to as diabetic embryopathy (DE). However, the pathogenic mechanisms underlying DE remain uncertain and there are no definitive tests to establish the diagnosis. Here, we explore the potential of DNA methylation as a diagnostic biomarker for DE and to inform disease pathogenesis. Read More

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http://www.nature.com/articles/s41436-019-0516-z
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http://dx.doi.org/10.1038/s41436-019-0516-zDOI Listing
April 2019
1 Read

Hepatic DNA methylation and expression profiles under prenatal restricted diet in three generations of female rat fetuses.

PLoS One 2019 16;14(4):e0215471. Epub 2019 Apr 16.

Institute of Human Nutrition and Dietetics, Poznan University of Life Sciences, Wojska Polskiego, Poznan, Poland.

The nutritional factors acting during early life can affect the development of the organism. It has been hypothesized that such programmed traits can be inherited by later generations. In this work, we present for the first time the effect of food deprivation in pregnant dams and its consequences for the transcription and DNA methylation profiles in the offspring of the next three generations. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215471PLOS
April 2019
2 Reads

A case-control analysis of maternal diet and risk of neural tube defects in Bangladesh.

Birth Defects Res 2019 Apr 15. Epub 2019 Apr 15.

Department of Neurology, Boston Children's Hospital, Boston, Massachusetts.

Objectives: Mothers need a nutrient-rich diet for healthy neural tube development. Neural tube defect risk can be reduced through fortifying grain products with folic acid and taking folic acid supplements. Fortification is not required in Bangladesh. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/bdr2.1505
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http://dx.doi.org/10.1002/bdr2.1505DOI Listing
April 2019
2 Reads

Maintaining Balance.

Authors:
Janet C King

Annu Rev Nutr 2019 Apr 12. Epub 2019 Apr 12.

Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California 94720-3104, USA.

Writing this biography forced me to look back over my career as a scientist, teacher, wife, and mother. To my surprise, a lifelong theme emerged that I was unaware of, that is, the role of maintaining balance between work and family, science and teaching, mentorship and administration, and personal values and challenges. My primary mentor, Dr. Read More

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https://www.annualreviews.org/doi/10.1146/annurev-nutr-08201
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http://dx.doi.org/10.1146/annurev-nutr-082018-124634DOI Listing
April 2019
2 Reads

Effectiveness of Peer Counselor Support on Breastfeeding Outcomes in WIC-Enrolled Women.

J Nutr Educ Behav 2019 Apr 10. Epub 2019 Apr 10.

Department of Public Health Sciences, University of Rochester School of Medicine and Dentistry, Rochester, NY.

Objective: To evaluate the effectiveness of different quantities and types of breastfeeding (BF) peer counselor (BFPC) support on BF outcomes in women enrolled in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC).

Design: Secondary data analysis using BFPC data from an upstate New York county WIC (April 1, 2009 to March 30, 2011) merged with New York State Department of Health WIC surveillance data.

Participants: A total of 2,149 WIC-enrolled mothers with live singleton births who accepted a BFPC referral and received different quantities and types of BFPC support (telephone, in person, and mailings). Read More

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http://dx.doi.org/10.1016/j.jneb.2019.03.005DOI Listing
April 2019
1 Read

Factors associated with low birth weight among babies born at Hawassa University Comprehensive Specialized Hospital, Hawassa, Ethiopia.

Ital J Pediatr 2019 Apr 11;45(1):48. Epub 2019 Apr 11.

Department of Midwifery, College of Medicine and Health Science, Hawassa University, Hawassa, Ethiopia.

Background: Low birth weight is defined as infant born with weight of less than 2500 g. It is one of the major public health problems worldwide. In Ethiopia, there are limited evidences on factors contributing to low birthweight. Read More

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http://dx.doi.org/10.1186/s13052-019-0637-7DOI Listing
April 2019
1 Read

Maternal multivitamin supplementation is associated with a reduced risk of autism spectrum disorder in children: a systematic review and meta-analysis.

Nutr Res 2019 Feb 24. Epub 2019 Feb 24.

Department of Nutrition and Food Hygiene, School of Public Health, Xinxiang Medical University, Xinxiang, Henan 453003, China.

Several studies have explored the link of antenatal multivitamin supplementation with autism spectrum disorder (ASD) in offspring, but the findings are inconsistent. The purpose of the current study was to perform a systematic review and meta-analysis of published studies to evaluate the actual association between maternal multivitamin supplementation during the prenatal period and the risk of ASD in children. PubMed, EMBASE, PsycINFO, Web of Science, and Cochrane Library were searched up to August 26, 2018. Read More

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http://dx.doi.org/10.1016/j.nutres.2019.02.003DOI Listing
February 2019
2 Reads

Prenatal exposure to organophosphate esters and behavioral development in young children in the Pregnancy, Infection, and Nutrition Study.

Neurotoxicology 2019 Apr 3;73:150-160. Epub 2019 Apr 3.

Department of Epidemiology, University of North Carolina at Chapel Hill, 135 Dauer Drive, 2101 McGavran-Greenberg Hall, Chapel Hill, NC, 27599, USA.

Organophosphate esters (OPEs) are commonly used as plasticizers and flame retardants in consumer products, and exposure is relatively ubiquitous in most populations studied. This may be of concern as some OPEs may be neurotoxic, endocrine-disrupting, and interfere with behavioral development; however, observational evidence is limited. We used data from the Pregnancy, Infection, and Nutrition Study, a prospective birth cohort study, to investigate associations between maternal OPE metabolite concentrations during pregnancy and behavioral development in offspring. Read More

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http://dx.doi.org/10.1016/j.neuro.2019.03.007DOI Listing
April 2019
3 Reads

Support during pregnancy for women at increased risk of low birthweight babies.

Cochrane Database Syst Rev 2019 Apr 1;4:CD000198. Epub 2019 Apr 1.

Monash Nursing and Midwifery, Monash University, Wellington Road, Clayton, Victoria, Australia, 3800.

Background: Studies consistently show a relationship between social disadvantage and low birthweight. Many countries have programmes offering special assistance to women thought to be at risk for giving birth to a low birthweight infant. These programmes, collectively referred to in this review as additional social support, may include emotional support, which gives a person a feeling of being loved and cared for, tangible/instrumental support, in the form of direct assistance/home visits, and informational support, through the provision of advice, guidance and counselling. Read More

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http://dx.doi.org/10.1002/14651858.CD000198.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443020PMC
April 2019
5 Reads

Risk factors for abdominal wall defects.

Congenit Anom (Kyoto) 2019 Apr 1. Epub 2019 Apr 1.

Department of Surgery (Paediatric Surgery Section), University of Ulm, Ulm, Germany.

In the last decades, prevalence of gastroschisis (GS) has increased worldwide. The purpose of this study was to identify maternal risk factors explaining the described gain and to identify differences between GS and omphalocele (OC). Case-control design was used to compare GS (n=36) and OC (n=18) mothers to control group (CG; n=30) matched for maternal age. Read More

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http://dx.doi.org/10.1111/cga.12336DOI Listing
April 2019
5 Reads

Prenatal Omega-6:Omega-3 Ratio and Attention Deficit and Hyperactivity Disorder Symptoms.

J Pediatr 2019 Mar 22. Epub 2019 Mar 22.

Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain; Pompeu Fabra University, Barcelona, Spain; Biomedical Research Networking Centres Epidemiology and Public Health (CIBERESP), Madrid, Spain; Hospital del Mar Medical Research Institute, Barcelona, Spain.

Objective: To evaluate whether higher omega-6:omega-3 (n-6:n-3) long-chain polyunsaturated fatty acid ratio in cord plasma is associated with more symptoms of attention deficit and hyperactivity disorder (ADHD) at 4 and 7 years of age.

Study Design: This study was based on a population-based birth cohort in Spain. N-6 arachidonic acid and n-3 eicosapentaenoic and docosahexaenoic acid concentrations were measured in cord plasma. Read More

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http://dx.doi.org/10.1016/j.jpeds.2019.02.022DOI Listing
March 2019
7 Reads

Use of Negative Control Exposure Analysis to Evaluate Confounding: An Example of Acetaminophen Exposure and Attention-Deficit/Hyperactivity Disorder in Nurses' Health Study II.

Am J Epidemiol 2019 Apr;188(4):768-775

Department of Environmental Health, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.

Frequent maternal use of acetaminophen in pregnancy has been linked to attention-deficit/hyperactivity disorder (ADHD) in children, but concerns regarding uncontrolled confounding remain. In this article, we illustrate use of the negative control exposure (NCE) approach to evaluate uncontrolled confounding bias in observational studies on pregnancy drug safety and explain the causal assumptions behind the method. We conducted an NCE analysis and evaluated the associations between maternal acetaminophen use during different exposure periods and ADHD among 8,856 children born in 1993-2005 to women enrolled in the Nurses' Health Study II cohort. Read More

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http://dx.doi.org/10.1093/aje/kwy288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438812PMC
April 2019
1 Read

Risk factors associated with the development of double-inlet ventricle congenital heart disease.

Birth Defects Res 2019 Mar 28. Epub 2019 Mar 28.

Division of Pediatric Cardiology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.

Background: Congenital heart disease (CHD) is the most common birth defect group and a significant contributor to neonatal and infant death. CHD with single ventricle anatomy, including hypoplastic left heart syndrome (HLHS), tricuspid atresia (TA), and various double-inlet ventricle (DIV) malformations, is the most complex with the highest mortality. Prenatal risk factors associated with HLHS have been studied, but such data for DIV are lacking. Read More

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http://dx.doi.org/10.1002/bdr2.1501DOI Listing
March 2019
7 Reads

Prenatal exposure to perfluorobutanesulfonic acid and childhood adiposity: A prospective birth cohort study in Shanghai, China.

Chemosphere 2019 Mar 19;226:17-23. Epub 2019 Mar 19.

Department of Pediatrics, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. Electronic address:

Background: Several per- and polyfluoroalkyl substances (PFAS) have been phased out due to their adverse effects, and replaced by the short-chain perfluorobutanesulfonic acid (PFBS). However, the long-term impacts of PFBS on human health are unknown.

Objective: We aimed to investigate the association between prenatal exposure to PFAS, especially PFBS and childhood adiposity at 5 years of age. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2019.03.095DOI Listing
March 2019
1 Read

Engaging Fathers in Early Obesity Prevention During the First 1,000 Days: Policy, Systems, and Environmental Change Strategies.

Obesity (Silver Spring) 2019 Apr;27(4):525-533

Department of Nutrition, Harvard T. H. Chan School of Public Health, Harvard University, Boston, Massachusetts, USA.

Objective: Fathers are critical stakeholders in childhood obesity prevention but are difficult to engage. This review presents a new approach to engaging fathers in obesity prevention during the first 1,000 days.

Methods: The review focuses on five existing health and social service programs, including prenatal care, pediatric care, the Special Supplemental Nutrition Program for Women, Infants, and Children, home visiting, and Early Head Start. Read More

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http://dx.doi.org/10.1002/oby.22395DOI Listing
April 2019
1 Read

Maternal alcohol use during pregnancy in a general national population in South Africa.

S Afr J Psychiatr 2019 17;25(0):1236. Epub 2019 Jan 17.

Department of Research Innovation and Development, University of Limpopo, South Africa.

Objective: Alcohol use in pregnancy is linked with various negative health effects on the infant. The aim of this study was to examine the prevalence of maternal alcohol use during pregnancy and socio-demographic and health correlates.

Methods: Data of ever-pregnant women from the cross-sectional 'South African National Health and Nutrition Examination Survey (SANHANES-1) 2011-2012' were analysed. Read More

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http://dx.doi.org/10.4102/sajpsychiatry.v25i0.1236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424534PMC
January 2019
2 Reads

A 25-year study of gastroschisis outcomes in a middle-income country.

J Pediatr Surg 2019 Feb 24. Epub 2019 Feb 24.

Department of Surgery, School of Medicine, Universidade Federal de Minas Gerais; Pediatric Surgical Service, Hospital das Clínicas of the Universidade Federal de Minas Gerais/Empresa, Brasileira, de Serviços Hospitalares. Belo Horizonte, Minas Gerais, Brazil.

Background: Survival of newborns with gastroschisis is significantly higher in high-income versus low and middle-income countries. We reviewed treatment and outcomes of gastroschisis in a middle-income country setting with increasing protocolized management.

Methods: All newborns with gastroschisis treated during the period 1989-2013 at a single Brazilian academic surgical service were studied retrospectively. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2019.02.020DOI Listing
February 2019
6 Reads

Associations of Prenatal and Postnatal Maternal Depressive Symptoms with Offspring Cognition and Behavior in Mid-Childhood: A Prospective Cohort Study.

Int J Environ Res Public Health 2019 Mar 20;16(6). Epub 2019 Mar 20.

Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA.

Exposure to maternal depressive symptoms in the peri-pregnancy periods may be associated with poorer child development, but research is often limited to only maternal assessments of behavior and cognition. This study investigates the specific periods of prenatal and postnatal exposure to maternal depressive symptoms in association with child development using reports from teachers and mothers. This study is based on 1225 mother⁻child pairs from Project Viva, a prospective pre-birth cohort study. Read More

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https://www.mdpi.com/1660-4601/16/6/1007
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http://dx.doi.org/10.3390/ijerph16061007DOI Listing
March 2019
6 Reads

An Exploratory Look at the Role of Childcare Providers as a Support and Resource for Breastfeeding Mothers.

Breastfeed Med 2019 Mar 21. Epub 2019 Mar 21.

2 Department of Human Development and Family Studies and University of Illinois at Urbana-Champaign, Urbana, Illinois.

Introduction: The childcare setting remains largely unexplored as a potential barrier to breastfeeding continuation and, therefore, the lack of interventions targeting childcare providers may be a missed opportunity for improved breastfeeding support. This article explores the perceptions of 25 first-time breastfeeding mothers on navigating the critical transition to childcare and the role of childcare providers regarding breastfeeding support.

Methods: Mothers were selected if they indicated an intent to breastfeed on a prenatal questionnaire and had enrolled their child in childcare. Read More

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http://dx.doi.org/10.1089/bfm.2018.0091DOI Listing
March 2019
1 Read

Prenatal and perinatal risk factors for eating disorders in women: A population cohort study.

Int J Eat Disord 2019 Mar 20. Epub 2019 Mar 20.

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Objective: The fetal programming model hypothesizes that developmental programming in utero and in early life induces adaptations that predetermine the adult phenotype. This study investigated whether prenatal/perinatal complications are associated with lifetime eating disorders in women.

Method: Participants included 46,373 adult women enrolled in the Norwegian Mother and Child Cohort Study (den norske Mor & barn-undersøkelsen [MoBa]). Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/eat.23073
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http://dx.doi.org/10.1002/eat.23073DOI Listing
March 2019
3 Reads

Prenatal Protein Malnutrition Leads to Hemispheric Differences in the Extracellular Concentrations of Norepinephrine, Dopamine and Serotonin in the Medial Prefrontal Cortex of Adult Rats.

Front Neurosci 2019 5;13:136. Epub 2019 Mar 5.

Division of Pediatric Gastroenterology and Nutrition, Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, MA, United States.

Exposure to prenatal protein malnutrition (PPM) leads to a reprogramming of the brain, altering executive functions involving the prefrontal cortex (PFC). In this study we used microdialysis to assess the effects of PPM on extracellular concentrations of norepinephrine (NE), dopamine (DA) and serotonin (5-HT) bilaterally in the ventral portion of the medial prefrontal cortex (vmPFC; ventral prelimbic and infralimbic cortices) of adult Long-Evans rats. Female Long-Evans rats were fed either a low protein (6%) or adequate protein diet (25%) prior to mating and throughout pregnancy. Read More

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http://dx.doi.org/10.3389/fnins.2019.00136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411819PMC
March 2019
2 Reads

Is Waist-to-Height Ratio Superior to Body Mass Index and Waist Circumference in Predicting the Incidence of Hypertension?

Ann Nutr Metab 2019 19;74(3):215-223. Epub 2019 Mar 19.

Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.

Background: It is still controversial which anthropometric indicator could be the best predictor of the incident hypertension.

Objectives: To examine the relative power of body mass index (BMI), waist circumference (WC), skinfold thickness, waist-to-hip ratio (WHR), and waist-to-height ratio (WHTR) in predicting the incidence of hypertension in Chinese adults.

Method: Data were obtained from the China Health and Nutrition Survey. Read More

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http://dx.doi.org/10.1159/000499073DOI Listing
March 2019
1 Read

Importance of prenatal and early-life nutrition in early menopause and subsequent health.

Authors:
Sybil L Crawford

Menopause 2019 Mar 18. Epub 2019 Mar 18.

University of Massachusetts Medical School, Graduate School of Nursing, Worcester, MA.

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http://dx.doi.org/10.1097/GME.0000000000001320DOI Listing
March 2019
1 Read

Partner social support during pregnancy and the postpartum period and inflammation in 3-month-old infants.

Biol Psychol 2019 Mar 15;144:11-19. Epub 2019 Mar 15.

Department of Pediatrics, University of Calgary, Calgary, AB, Canada. Electronic address:

Prenatal social stress "programs" offspring immune activity in animal models, but how the prenatal social environment affects human offspring inflammation is not known. Here, we test associations between prenatal partner support quality, i.e. Read More

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http://dx.doi.org/10.1016/j.biopsycho.2019.03.005DOI Listing
March 2019
1 Read

Examining Associations between Perinatal and Postnatal Risk Factors for Childhood Obesity Using Sibling Comparisons.

Child Obes 2019 Mar 18. Epub 2019 Mar 18.

5 Division of General Academic Pediatrics, Department of Pediatrics, Massachusetts General Hospital for Children, Boston, MA.

Background: One of the major criticisms of observational studies examining risk factors for childhood obesity is unmeasured confounding. We examined the associations between breastfeeding initiation, cesarean delivery, prenatal smoking, and gestational diabetes mellitus (GDM) with childhood obesity using both a traditional observational approach and a sibling-pair design with family fixed effects.

Methods: We used data from the Linked the Collecting Electronic Nutrition Trajectory Data Using e-Records of Youth (CENTURY) Study, a clinical database created through the linkage of well-child visits with children's birth certificates, with obesity measured at 2 (N = 55,058) and 5 (N = 43,894) years of age. Read More

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http://dx.doi.org/10.1089/chi.2018.0335DOI Listing
March 2019
2 Reads

The role of marine omega-3 in human neurodevelopment, including Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder - a review.

Crit Rev Food Sci Nutr 2019 Mar 18:1-16. Epub 2019 Mar 18.

a Department of Clinical Neurosciences and Mental Health, Medical Psychology, Faculty of Medicine , University of Porto , Porto , Portugal.

Autism Spectrum Disorders (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) are two increasingly prevalent neurodevelopmental disorders. This rise may be associated with a higher dietary intake of n-6 polyunsaturated fatty acids (PUFAs) and lower of n-3 PUFAs. Docosahexaenoic acid (DHA), a key nutritional n-3 PUFA, is crucial for an optimal offspring's neurodevelopment through the last trimester of pregnancy. Read More

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https://www.tandfonline.com/doi/full/10.1080/10408398.2019.1
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http://dx.doi.org/10.1080/10408398.2019.1573800DOI Listing
March 2019
6 Reads

Environmental Epigenetic Changes, as Risk Factors for the Development of Diseases in Children: A Systematic Review.

Ann Glob Health 2018 Jul 27;84(2):212-224. Epub 2018 Jul 27.

Toxicology Department, Cinvestav, Mexico City, MX.

Background: Children are susceptible to environmental contaminants and are at risk of developing diseases, more so if the exposure begins at an early age. Epidemiological studies have postulated the hypothesis of the fetal origin of disease, which is mediated by epigenetic changes. Epigenetic marks are inheritable; they modulate the gene expression and can affect human health due to the presence of environmental factors. Read More

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http://dx.doi.org/10.29024/aogh.909DOI Listing
July 2018
1 Read

Calcium and vitamin D supplementation and/or periodontal therapy in the treatment of periodontitis among Brazilian pregnant women: protocol of a feasibility randomised controlled trial (the IMPROVE trial).

Pilot Feasibility Stud 2019 5;5:38. Epub 2019 Mar 5.

9Department of Psychology, Social Work & Counselling, Faculty of Education and Health, University of Greenwich, Old Royal Naval College, Park Row, London, SE10 9LS UK.

Background: Periodontitis is a common oral inflammation, which is a risk factor for adverse pregnancy outcomes. Intakes of vitamin D and calcium are inversely associated with occurrence and progression of periodontitis. This study aims to assess the feasibility of a multi-component intervention, including provision of milk powder supplemented with calcium and vitamin D and periodontal therapy (PT), for improving maternal periodontal health and metabolic and inflammatory profiles of low-income Brazilian pregnant women with periodontitis. Read More

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http://dx.doi.org/10.1186/s40814-019-0417-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402123PMC
March 2019
2 Reads

Impacts of nutrition on the proliferation and differentiation of satellite cells in livestock species.

Authors:
Kara J Thornton

J Anim Sci 2019 Mar 14. Epub 2019 Mar 14.

Department of Animal, Dairy and Veterinary Science, Utah State University, Logan, Utah, 84322.

Nutrition and other external factors are known to have a marked effect on growth of skeletal muscle, modulated, at least in part, through effects on satellite cells. Satellite cells and their embryonic precursors play an integral role in both prenatal and postnatal skeletal muscle growth of mammals. Changes in maternal nutrition can impact embryonic muscle progenitor cells which ultimately impacts both prenatal and postnatal skeletal muscle development. Read More

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http://dx.doi.org/10.1093/jas/skz081DOI Listing
March 2019
1 Read

Association between food insecurity and perinatal risk factors with hearing problems in preterm birth.

Nutr Hosp 2019 Apr;36(2):267-274

Division of Sciences and Engineering. Universidad de Guanajuato.

Introduction: Background: hearing disorders in the premature newborns impact on their development and language and therefore, on their quality of life. Several risk factors have been associated to these conditions, but little is known about socioeconomic, nutrition factors and food security. Objective: to analyze the association between food security and prenatal risk factors in newborns with hearing disorders. Read More

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http://dx.doi.org/10.20960/nh.2193DOI Listing
April 2019
1 Read

PEARLS randomized lifestyle trial in pregnant Hispanic women with overweight/obesity: gestational weight gain and offspring birthweight.

Diabetes Metab Syndr Obes 2019 18;12:225-238. Epub 2019 Feb 18.

Center for Clinical Research and Health Promotion, School of Dental Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PR, USA,

Background: Inappropriate gestational weight gain (GWG) has been associated with adverse perinatal events. High rates of GWG have been reported among Hispanic women. Observational studies indicate that dietary and physical activity interventions during the prenatal period may improve maternal and infant health, but very few randomized trials have been conducted among high-risk overweight/obese Hispanic women. Read More

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http://dx.doi.org/10.2147/DMSO.S179009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385743PMC
February 2019
5 Reads

The Ramazzini Institute 13-week pilot study glyphosate-based herbicides administered at human-equivalent dose to Sprague Dawley rats: effects on development and endocrine system.

Environ Health 2019 03 12;18(1):15. Epub 2019 Mar 12.

Cesare Maltoni Cancer Research Center (CMCRC), Ramazzini Institute (RI), Via Saliceto, 3, 40010, Bentivoglio, Bologna, Italy.

Background: Glyphosate-based herbicides (GBHs) are broad-spectrum herbicides that act on the shikimate pathway in bacteria, fungi, and plants. The possible effects of GBHs on human health are the subject of an intense public debate for both its potential carcinogenic and non-carcinogenic effects, including potential effects on the endocrine system The present pilot study examine whether exposure to GBHs at the dose of glyphosate considered to be "safe" (the US Acceptable Daily Intake - ADI - of 1.75 mg/kg bw/day), starting from in utero life, affect the development and endocrine system across different life stages in Sprague Dawley (SD) rats. Read More

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http://dx.doi.org/10.1186/s12940-019-0453-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413565PMC

Prenatal Protein Malnutrition Produces Resistance to Distraction Similar to Noradrenergic Deafferentation of the Prelimbic Cortex in a Sustained Attention Task.

Front Neurosci 2019 19;13:123. Epub 2019 Feb 19.

Department of Psychology, University of New Hampshire, Durham, NH, United States.

Exposure to malnutrition early in development increases likelihood of neuropsychiatric disorders, affective processing disorders, and attentional problems later in life. Many of these impairments are hypothesized to arise from impaired development of the prefrontal cortex. The current experiments examine the impact of prenatal malnutrition on the noradrenergic and cholinergic axons in the prefrontal cortex to determine if these changes contribute to the attentional deficits seen in prenatal protein malnourished rats (6% casein vs. Read More

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https://www.frontiersin.org/article/10.3389/fnins.2019.00123
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http://dx.doi.org/10.3389/fnins.2019.00123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396814PMC
February 2019
7 Reads

Association between prenatal particulate air pollution exposure and telomere length in cord blood: Effect modification by fetal sex.

Environ Res 2019 Mar 2;172:495-501. Epub 2019 Mar 2.

Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Kravis Children's Hospital, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

Introduction: In utero particulate matter exposure produces oxidative stress that impacts cellular processes that include telomere biology. Newborn telomere length is likely critical to an individual's telomere biology; reduction in this initial telomere setting may signal increased susceptibility to adverse outcomes later in life. We examined associations between prenatal particulate matter with diameter ≤2. Read More

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http://dx.doi.org/10.1016/j.envres.2019.03.003DOI Listing
March 2019
4 Reads

Prenatal manganese and cord blood mitochondrial DNA copy number: Effect modification by maternal anemic status.

Environ Int 2019 May 5;126:484-493. Epub 2019 Mar 5.

Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Introduction: Manganese (Mn) is an essential nutrient but also a toxicant at high exposures, when it can induce oxidative stress (OS). Mn uptake is inversely correlated with iron status, therefore anemic individuals may be more susceptible to Mn overload induced-OS, which can manifest as changes in mitochondrial DNA copy number (mtDNA CN). Our objectives were to: 1) determine stage-specific associations of prenatal Mn exposure with cord blood MtDNA CN; and 2) investigate effect modification by maternal anemia, ferritin, and mean corpuscular volume (MCV). Read More

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http://dx.doi.org/10.1016/j.envint.2019.02.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471611PMC
May 2019
1 Read

The associations between lead exposure at multiple sensitive life periods and dental caries risks in permanent teeth.

Sci Total Environ 2019 Mar 14;654:1048-1055. Epub 2018 Nov 14.

Department of Cariology, Operative Dentistry and Dental Public Health, Indiana University School of Dentistry, Indianapolis, IN, USA. Electronic address:

Background: Dental caries is an important public health problem in Mexico, a country also faced with high exposure to toxicants including lead (Pb).

Methods: Participants were 386 children living in Mexico City. Prenatal (trimester 1-3), early-childhood (12, 24, 36, and 48 months of age) and peri-pubertal (10-18 years of age) blood Pb levels were quantified using graphite-furnace atomic-absorption spectroscopy. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.11.190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407640PMC
March 2019
1 Read
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A new variant of type III jejunoileal atresia.

J Pediatr Surg 2019 Feb 18. Epub 2019 Feb 18.

Department of Surgery, Boston Children's Hospital, Boston, MA. Electronic address:

Jejunoileal atresia (JIA) is a congenital defect that can result in significant loss of bowel length. The traditional classification of JIA was first proposed by Grosfeld and includes 4 subtypes. Among these, type IIIB, or apple-peel atresia, is characterized by a proximal atretic jejunum and a distal segment of spiraled bowel that terminates at the cecum. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2019.02.003DOI Listing
February 2019
5 Reads

Gestational nutrition 1: alterations to gestational nutrition can increase indicators of fertility in sheep.

Reproduction 2019 03;157(3):199-213

Animal Science, AgResearch, Invermay Agricultural Centre, Mosgiel, New Zealand.

The aim of this study was to examine the relationships between gestational nutrition, fetal ovarian development and offspring fertility in female sheep and to highlight the potential mechanisms underlying these relationships. Adult sheep (n = 79) were fed either a maintenance or 0.6 of maintenance plane of nutrition for the first 55 days of gestation and thereafter fed ad libitum. Read More

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http://dx.doi.org/10.1530/REP-18-0357DOI Listing

[Vegetarian diet in pregnancy and lactation - safety and rules of balancing meal plan in the aspect of optimal fetal and infant development].

Pol Merkur Lekarski 2019 Jan;46(271):45-50

Chair and Department of Neonatology, Medical University of Wrocław, Poland.

Pregnancy is a period of intense fetal development, as well as maternal physiological adaptation. During this period a varied diet is particularly important, as intake of macronutrients and micronutrients directly affects pregnancy outcome and the quality of breast milk. The dietary recommendations for pregnant women are indeed very similar to those for other adults, but with a few remarkable exceptions. Read More

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January 2019
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Extending Tests of Random Effects to Assess for Measurement Invariance in Factor Models.

Stat Biosci 2018 Dec 29;10(3):634-650. Epub 2018 Sep 29.

Department of Biostatistics, University of Michigan, Ann Arbor, U.S.A.

Factor analysis models are widely used in health research to summarize hard to measure predictor or outcome variable constructs. For example, in the ELEMENT study, factor models are used to summarize lead exposure biomarkers which are thought to indirectly measure prenatal exposure to lead. Classic latent factor models are fitted assuming that factor loadings are constant across all covariate levels (e. Read More

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http://dx.doi.org/10.1007/s12561-018-9222-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385881PMC
December 2018
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Effect of Prenatal Docosahexaenoic Acid Supplementation on Blood Pressure in Children With Overweight Condition or Obesity: A Secondary Analysis of a Randomized Clinical Trial.

JAMA Netw Open 2019 Feb 1;2(2):e190088. Epub 2019 Feb 1.

Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City.

Importance: The blood pressure-lowering property of docosahexaenoic acid (DHA) in children and adults is known, and an observational study from the Netherlands has linked higher intrauterine DHA exposure to lower childhood blood pressure. However, the association of prenatal intake of DHA supplement with childhood blood pressure has not been evaluated in randomized clinical trials.

Objective: To determine the effect of DHA supplementation during pregnancy on childhood blood pressure. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2019.0088DOI Listing
February 2019
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Malnutrition and its associated factors: a cross-sectional study with children under 2 years in a suburban area in Angola.

BMC Public Health 2019 Feb 21;19(1):220. Epub 2019 Feb 21.

Post-Graduation Program in Epidemiology, Federal University of Rio Grande do Sul (UFRGS), Rua Ramiro Barcellos, 2400/2° andar, CEP, Porto Alegre, RS, 90035-003, Brazil.

Background: The prevalence of child malnutrition in Angola is still very high, and little is known about its associated factors. The aim of this study was to identify these factors in children under 2 years in a suburban area of the country's capital city.

Methods: We used data from a cross-sectional population-based study conducted in 2010. Read More

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http://dx.doi.org/10.1186/s12889-019-6543-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385448PMC
February 2019
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Implementing a best-practice model of gestational diabetes mellitus care in dietetics: a qualitative study.

BMC Health Serv Res 2019 Feb 14;19(1):122. Epub 2019 Feb 14.

Cairns and Hinterland Hospital and Health Service and College of Healthcare Sciences, James Cook University, Cairns, 4870, Australia.

Background: Translating research into clinical practice is challenging for health services. Emerging approaches in implementation science recognise the need for a theory-driven approach to identify and overcome barriers to guideline adherence. However, many clinicians do not have the capacity, confidence, or expertise to realise change in their local settings. Read More

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http://dx.doi.org/10.1186/s12913-019-3947-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376709PMC
February 2019
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Rising rates of cesarean delivery in Ecuador: Socioeconomic and institutional determinants over two decades.

Birth 2019 Feb 13. Epub 2019 Feb 13.

Department of Anthropology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Background: Ecuador's cesarean delivery rate far exceeds that recommended by the Pan American Health Organization (PAHO) and the World Health Organization (WHO). Using data from three iterations of Ecuador's nationally representative, population-based survey Encuesta Nacional de Salud y Nutrición (ENSANUT/ENDEMAIN), spanning 23 years, this study examines women's mode of delivery outcomes by sociodemographic characteristics and hospital type (private, public, social security) in light of Ecuador's major health care reform over the past two decades.

Methods: Using data from the 1994, 2004, and 2012 iterations of the data set, we analyzed trends in cesarean delivery based on province, year, and institution of care. Read More

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http://dx.doi.org/10.1111/birt.12421DOI Listing
February 2019
5 Reads

No Associations Between Serum Lipid Levels or HOMA-IR and Asthma in Children and Adolescents: a NHANES Analysis

J Clin Res Pediatr Endocrinol 2019 Feb 14. Epub 2019 Feb 14.

Division of Pulmonary Medicine, Children’s Hospital of Shanghai (Jing An Branch), Shanghai Jiao Tong University, Shanghai 200040

Objective: Studies have reported inconsistent results of the associations between lipids and insulin resistance (IR) and asthma. The purpose of this study was to examine the associations between abnormal serum lipid levels and homeostatic model assessment-insulin resistance (HOMA-IR) and the presence of current asthma in children and adolescents.

Methods: The United States National Health and Nutrition Examination Survey database from 1999 to 2012 was randomly searched for children (aged 3-11 years) and adolescents (aged 12-19 years) with and without asthma and with complete demographic and clinical data of interest. Read More

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http://dx.doi.org/10.4274/jcrpe.galenos.2019.2018.0098DOI Listing
February 2019
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Maternal Choline Supplementation Modulates Placental Markers of Inflammation, Angiogenesis, and Apoptosis in a Mouse Model of Placental Insufficiency.

Nutrients 2019 Feb 12;11(2). Epub 2019 Feb 12.

Division of Nutritional Sciences, Cornell University, Ithaca, NY 14850, USA.

(distal-less homeobox 3) haploinsufficiency in mice has been shown to result in restricted fetal growth and placental defects. We previously showed that maternal choline supplementation (4X versus 1X choline) in the +/- mouse increased fetal and placental growth in mid-gestation. The current study sought to test the hypothesis that prenatal choline would modulate indicators of placenta function and development. Read More

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http://dx.doi.org/10.3390/nu11020374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412879PMC
February 2019
1 Read