Search Our Scientific Publications & Authors

J Arrhythm 2019 Apr 15;35(2):252-261. Epub 2019 Feb 15.

Cardiovascular Center Munakata Suikokai General Hospital Fukutsu Japan.

Objective: This study aimed to investigate the effects of radiofrequency catheter ablation (RFCA) and clinical and electrophysiological characteristics in symptomatic patients with premature ventricular contractions (PVCs) from near the His-bundle (His-PVCs).

Methods: The patient characteristics, prevalence of complications with any life style related disease (ALSRD) including hypertension, dyslipidemia, or diabetes mellitus, and/or cardiovascular disease (CVD) including coronary artery disease, cerebrovascular disease, renal dysfunction, or cardiomyopathy, clinical status, frequency of PVCs evaluated by 24hour Holter monitoring, echocardiography including the left ventricular diastolic dysfunction (LVDD) parameters, and electrophysiological findings were evaluated in 14 consecutive symptomatic patients with His-PVCs.

Results: The prevalence of males, being elderly and/or slightly obese, current and/or history of smoking, ALSRD or CVD related complications, and LVDD probably resulting from ALSRD and/or CVD complications were higher in patients with His-PVCs. Read More

Heart Rhythm 2019 Apr 17. Epub 2019 Apr 17.

Gill Heart and Vascular Institute, University of Kentucky. Electronic address:

Background: Frequent premature ventricular contractions (PVCs) can cause disabling symptoms and decrease left ventricle ejection fraction. The PVC burden, typically quantified by a 24-hour monitor, is one of the factors that determines the clinical management of PVCs.

Objective: Evaluate the extent of variability in 24-hour PVC burden during a 14-day ambulatory cardiac monitor among patients with significant PVC burden. Read More

Heart Rhythm 2019 Apr 17. Epub 2019 Apr 17.

Department of Cardiac Electrophysiology, Northwell Health - Lenox Hill Heart and Lung 100 East 77th Street New York, NY-10021.

Background: Idiopathic arrhythmias commonly arise from the septal right ventricular outflow tract (sRVOT), sinuses of Valsalva (SoV) and great cardiac vein (GCV). Predicting exact site of origin is important for preparation for catheter ablation.

Objectives: To examine diagnostic value of non-invasive electroanatomic mapping (NIEAM) to differentiate between sRVOT, SoV and GCV origin and compare it to that of 12-lead ECG. Read More

JACC Clin Electrophysiol 2019 Apr;5(4):528-529

Pacing and Electrophysiology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal.

J Cardiovasc Electrophysiol 2019 Apr 14. Epub 2019 Apr 14.

Medizinische Klinik 1, HELIOS Klinikum München-West, Akademisches Lehrkrankenhaus der Universität München, Germany.

Introduction: Concealed structural abnormalities were detected by delayed enhancement - magnetic resonance imaging (DE-MRI) in patients with apparently idiopathic tachycardia of left ventricular (LV) origin. Basal septal fibrosis was evaluated as a potential arrhythmia substrate in patients with left ventricular outflow tract (LVOT) arrhythmias.

Methods And Results: 22 patients with LVOT arrhythmias, including frequent monomorphic premature ventricular complexes (PVCs) in 15 patients and ventricular tachycardia (VT) in 7 patients, underwent catheter ablation and DE-MRI. Read More

Physiol Meas 2019 Apr 10. Epub 2019 Apr 10.

Department of Biomedical Informatics, Emory University, 36 Eagle Row, #571, MS 2045-001-1AC, Atlanta, GA 30322, Atlanta, Georgia, UNITED STATES.

\emph{Objective:} Ventricular contractions in healthy individuals normally follow the contractions of atria to facilitate more efficient pump action and cardiac output. With a ventricular ectopic beat (VEB), volume within the ventricles are pumped to the body's vessels before receiving blood from atria, thus causing inefficient blood circulation. VEBs tend to cause perturbations in the instantaneous heart rate time series, making the analysis of heart rate variability inappropriate around such events, or requiring special treatment (such as signal averaging). Read More

J Cardiovasc Electrophysiol 2019 Apr 9. Epub 2019 Apr 9.

UCLA Cardiac Arrhythmia Center, David Geffen School of Medicine at UCLA, Los Angeles, California.

Introduction: Frequent premature ventricular complexes (PVCs) can lead to symptoms, such as cardiomyopathy and increased mortality. Beta-blockers are recommended as first-line therapy to reduce PVC burden; however, the response is unpredictable. The objective of this study is to determine whether PVC diurnal-variability patterns are associated with different clinical profiles and predict drug response. Read More

Sensors (Basel) 2019 Mar 28;19(7). Epub 2019 Mar 28.

Institute of Imaging and Biomedical Photonics, National Chiao Tung University, Tainan 711, Taiwan.

A standard 12-lead electrocardiogram (ECG) is an important tool in the diagnosis of heart diseases. Here, Ag/AgCl electrodes with conductive gels are usually used in a 12-lead ECG system to access biopotentials. However, using Ag/AgCl electrodes with conductive gels might be inconvenient in a prehospital setting. Read More

G Ital Cardiol (Rome) 2019 Apr;20(4):223-228

U.O.S. Aritmologia, Cardiologia, Ospedale Maggiore, Bologna.

Premature ventricular complexes (PVCs) are usually benign, and commonly only severely symptomatic patients are treated. In the literature, frequent PVCs have been reported to cause ventricular dysfunction, which may improve after PVC treatment. PVCs can also worsen the prognosis in patients with structural heart disease. Read More

Eur Heart J 2019 Mar 27. Epub 2019 Mar 27.

Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Carnegie 568D, 600 N. Wolfe St. Baltimore, MD 21287, USA.

Aims: Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is characterized by ventricular arrhythmias (VAs) and sudden cardiac death (SCD). We aimed to develop a model for individualized prediction of incident VA/SCD in ARVC patients.

Methods And Results: Five hundred and twenty-eight patients with a definite diagnosis and no history of sustained VAs/SCD at baseline, aged 38. Read More

Europace 2019 Mar 24. Epub 2019 Mar 24.

Hospital Clínic and IDIBAPS, Barcelona, Spain.

Aims: Ablation of frequent premature ventricular complexes (PVCs) improves left ventricular ejection fraction in patients with left ventricular (LV) systolic dysfunction. This study aims to evaluate the long-term hard outcomes and potential prognostic variables in this population.

Methods And Results: Prospective multicentre study including 101 consecutive patients [56 ± 12 years old, 62 (61%) men] with LV systolic dysfunction and frequent PVCs who underwent PVC ablation before November 2015. Read More

JACC Clin Electrophysiol 2019 Mar;5(3):401-403

Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.

J Electrocardiol 2019 Mar 7;54:47-48. Epub 2019 Mar 7.

Arrhythmology Unit - Ospedale S. Giovanni Calibita, Fatebenefratelli Isola Tiberina, Rome, Italy.

Recognition of pre-potentials during activation mapping of aortic cusp premature ventricular contractions is useful to localize the precise site of origin and is an indicator of successful ablation, but sometimes these electrograms can be blunt and have low amplitude. High resolution mapping in the aortic cusp region allows improved near field detection of these signals in very few beats. Read More

HeartRhythm Case Rep 2019 Mar 7;5(3):155-158. Epub 2018 Dec 7.

Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.

HeartRhythm Case Rep 2019 Mar 30;5(3):120-123. Epub 2018 Nov 30.

Section of Electrophysiology, Division of Cardiovascular Disease, Duke University Hospital, Durham, North Carolina.

Clin J Am Soc Nephrol 2019 Apr 19;14(4):549-556. Epub 2019 Mar 19.

Kidney Research Institute.

Background And Objectives: Cardiac arrhythmias increase mortality and morbidity in CKD. We evaluated the rates of subclinical arrhythmias in a population with type 2 diabetes and patients with moderate to severe CKD who were not on dialysis.

Design, Setting, Participants & Measurements: This is a prospective observational study, using continuous ambulatory cardiac monitors to determine the rate of atrial and ventricular arrhythmias, as well as conduction abnormalities in this group. Read More

Clin Case Rep 2019 Feb 9;7(2):322-327. Epub 2019 Jan 9.

Department of Cardiovascular, Respiratory, Nephrology, Anaesthesiology and Geriatric Sciences of "Sapienza" University of Rome Rome Italy.

Delayed efficacy of radiofrequency energy can suppress ventricular arrhythmias after a failed ablation procedure. The implant of cardiac defibrillator for arrhythmia-induced cardiomyopathy should be procrastinated after a period of follow-up. Waiting for delayed efficacy is a reasonable choice to reduce the risk of complications associated with aggressive ablative approaches. Read More

J Electrocardiol 2019 Feb 7;54:18-21. Epub 2019 Feb 7.

Division of Cardiology, Kingston Health Science Center, Queen's University, Kingston, Ontario, Canada.

Advanced interatrial block (IAB) (P-wave ≥120 ms and biphasic P-wave in leads II, III and aVF) is a prevalent ECG pattern frequently associated with supraventricular arrhythmias and stroke, especially in patients with structural heart disease. Intermittent IAB is a much more poorly defined electrocardiographic entity with uncertain clinical significance. In this case series, we review and analyze eight cases of second degree intermittent IAB. Read More

Indian Pacing Electrophysiol J 2019 Feb 26. Epub 2019 Feb 26.

Ankara University, Cardiology Department, Ankara, Turkiye.

Ablation of premature ventricular complexes (PVCs) originating from left ventricular outflow tract (LVOT)/left ventricular summit (LVS) is challenging with considerable rate of failure. Recently, in a novel approach to ablation of these arrythmias, application of radiofrequency energy to anatomically opposite sites of presumed origin of arrythmia, has been associated with moderate procedure success. Although late elimination of PVCs that are persistent following an ablation procedure has been previously reported, this observation has not been studied sufficiently. Read More

Neth Heart J 2019 Apr;27(4):208-213

Heart Rhythm Services, University of British Columbia, Vancouver, BC, Canada.

Introduction: Phospholamban cardiomyopathy is an inherited cardiomyopathy, characterised by a defect in regulation of the sarcoplasmic reticulum Ca pump, often presenting with malignant arrhythmias and progressive cardiac dysfunction occurring at a young age.

Methods: Phospholamban R14del mutation carriers and family members were identified from inherited arrhythmia clinics at 13 sites across Canada. Cardiac investigations, including electrocardiograms, Holter monitoring (premature ventricular complexes, PVCs), and imaging results were summarised. Read More

J Arrhythm 2019 Feb 12;35(1):149-151. Epub 2018 Nov 12.

Arrhythmology Unit Ospedale S. Giovanni Calibita Fatebenefratelli Isola Tiberina Rome Italy.

A 23-year-old athlete with symptomatic low burden premature ventricular contraction (PVC) with left bundle branch block morphology and inferior axis morphology was sent to our department for RV mapping and PVC ablation. Exit zone of the PVC was easily and clearly defined by the bipoles A3-A4 achieving optimal and detailed pacemapping (Panels A-C) near the His bundle (yellow dots). The spatial conformation and the smooth shape of the catheter would definitely help everyday procedures in the setting of low burden PVC/noninducible focal ventricular arrhythmia, especially when the focus is located very close to the conductive tissue. Read More

J Arrhythm 2019 Feb 21;35(1):92-98. Epub 2018 Nov 21.

Cardiology Revere Health Provo Utah.

Background: Catheter ablation of para-Hisian (PH) premature ventricular complexes (PVCs) has a high risk of heart block. This study aimed to find the electrocardiographic (ECG) predictors of PH-PVCs.

Methods: We enrolled 47 patients who underwent an electrophysiologic study for catheter ablation of PVCs and analyzed the ECG characteristics, retrospectively. Read More

Clin Res Cardiol 2019 Feb 20. Epub 2019 Feb 20.

Department of Cardiology, Ziekenhuis Oost-Limburg, Schiepse Bos 6, 3600, Genk, Belgium.

Background: Sacubitril/valsartan reduced the occurrence of sudden cardiac death in the PARADIGM-HF trial. However, limited information is available about the mechanism.

Methods: Heart failure (HF)-patients receiving sacubitril/valsartan for a class-I indication equipped with an implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy (CRT) with remote tele-monitoring were retrospectively analyzed. Read More

Heart Rhythm 2019 Feb 14. Epub 2019 Feb 14.

Centre for Heart Rhythm disorders (CHRD), South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia. Electronic address:

Background: Atrial fibrillation (AF) is common after pacemaker implantation. However, the impact of pacemaker algorithms in AF prevention is not well understood.

Objective: The purpose of this study was to evaluate the role of pacing algorithms in preventing AF progression. Read More

Clin Res Cardiol 2019 Feb 15. Epub 2019 Feb 15.

Semmelweis University Heart and Vascular Centre, Városmajor u. 68, Budapest, 1122, Hungary.

Objective: Patients with electrical injury are considered to be at high risk of cardiac arrhythmias. Due to the small number of studies, there is no widely accepted guideline regarding the risk assessment and management of arrhythmic complications after electrical accident (EA). Our retrospective observational study was designed to determine the prevalence of ECG abnormalities and cardiac arrhythmias after EA, to evaluate the predictive value of cardiac biomarkers for this condition and to assess in-hospital and 30-day mortality. Read More

J Diabetes 2019 Feb 15. Epub 2019 Feb 15.

Department of Endocrinology, Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China.

Background: Cardiovascular autonomic neuropathy (CAN) is a risk factor for arrhythmias and adverse cardiovascular events, but the relationship between CAN severity and nocturnal arrhythmias needs to be clarified. This study evaluated the association between nocturnal arrhythmias and CAN severity in patients with type 2 diabetes (T2D).

Methods: In all, 219 T2D patients were recruited from January 2017 to May 2018. Read More

Pacing Clin Electrophysiol 2019 04 12;42(4):487-488. Epub 2019 Mar 12.

Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Pacing Clin Electrophysiol 2019 04 21;42(4):486. Epub 2019 Feb 21.

Department of Cardiology, Arrhythmia and Electrophysiology Unit, Hacettepe University, Ankara, Turkey.

Heart Lung Circ 2019 Mar;28(3):351-353

The University of Newcastle, Newcastle, NSW, Australia; Cardiovascular Department, John Hunter Hospital, Newcastle, NSW, Australia; Hunter Medical Research Institute, Newcastle, NSW, Australia. Electronic address:

Heart Rhythm 2019 Jan 31. Epub 2019 Jan 31.

Cardiovascular Division, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address:

Background: Catheter ablation for polymorphic ventricular tachycardia and ventricular fibrillation (PMVT/VF) may target triggering premature ventricular contractions (PVCs). Targeting ventricular scar has also been suggested, but data are limited.

Objective: The purpose of this study was to characterize the electrophysiological findings and ablation outcomes for patients with PMVT/VF and structural heart disease (SHD) compared to those with idiopathic VF. Read More

Ann Cardiol Angeiol (Paris) 2019 Jan 22. Epub 2019 Jan 22.

Centre de médecine et des sciences de sport, Tunis, Tunisia.

Introduction: Premature ventricular complexes (PVC) are generally considered as a benign electrocardiographic abnormality in the athletic population. However it may be indicative of underlying heart disease which may increase the risk of sudden death. This implies the need for cardiological evaluation before indicating the ability to practice competitive sports. Read More

Sci Total Environ 2019 Mar 12;657:1285-1293. Epub 2018 Dec 12.

Department of Occupational and Environmental Health, Peking University School of Public Health, Peking University Institute of Environmental Medicine, Beijing, China; Key Laboratory of Molecular Cardiovascular Sciences of Ministry of Education, Peking University, Beijing, China. Electronic address:

Epidemiological evidence linking source-specific ambient particulate matter with aerodynamic diameter <2.5 μm (PM) and cardiac arrhythmias is limited. In this study, we investigated the impact of source-specific PM on cardiac arrhythmias in a panel of forty-five healthy adults living in Beijing, China, between 2015 and 2016. Read More

Australas Phys Eng Sci Med 2019 Mar 14;42(1):149-157. Epub 2019 Jan 14.

Department of Biomedical Systems and Informatics Engineering, Yarmouk University, Irbid, Jordan.

Electrocardiogram (ECG) beat classification is a significant application in computer-aided analysis and diagnosis technologies. This paper proposed a method to detect, extract informative features, and classify ECG beats utilizing real ECG signals available in the standard MIT-BIH Arrhythmia database, with 10,502 beats had been extracted from it. The present study classifies the ECG beat into six classes, normal beat (N), Left bundle branch block beat, Right bundle branch block beat, Premature ventricular contraction, atrial premature beat, and aberrated atrial premature, using Gaussian mixture and wavelets features, and by applying principal component analysis for feature set reduction. Read More

Comput Methods Programs Biomed 2019 Feb 27;169:59-69. Epub 2018 Dec 27.

Telecommunication and Aeronautic Engineering, São Paulo State University (UNESP), São João da Boa Vista, Brazil. Electronic address:

Background And Objective: Premature ventricular contraction is associated to the risk of coronary heart disease, and its diagnosis depends on a long time heart monitoring. For this purpose, monitoring through Holter devices is often used and computational tools can provide essential assistance to specialists. This paper presents a new premature ventricular contraction recognition method based on a simplified set of features, extracted from geometric figures constructed over QRS complexes (Q, R and S waves). Read More

Nephrol Dial Transplant 2019 Jan 9. Epub 2019 Jan 9.

Cardiorenal Translational Laboratory, Institute of Research i+12, Hospital Universitario 12 de Octubre, Madrid, Spain.

Background: Cardiac dysfunction and arrhythmia are common and onerous cardiovascular events in end-stage renal disease (ESRD) patients, especially those on dialysis. Fibroblast growth factor (FGF)-23 is a phosphate-regulating hormone whose levels dramatically increase as renal function declines. Beyond its role in phosphorus homeostasis, FGF-23 may elicit a direct effect on the heart. Read More

Heart Rhythm 2019 Jan 4. Epub 2019 Jan 4.

Heart Rhythm Center, Centro Cardiologico Monzino IRCCS, Milan, Italy; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

Background: The effectiveness of radiofrequency catheter ablation (RFCA) in atrial tachyarrhythmias correlates with lesion transmurality. Ablation Index (AI) is an index that incorporates contact force, time, and radiofrequency power simultaneously and is able to predict lesion size and outcomes in RFCA of atrial fibrillation.

Objective: The purpose of this study was to assess whether AI could be an acute and long-term success predictor in RFCA of premature ventricular complexes (PVCs). Read More

Vet J 2019 Jan 12;243:21-25. Epub 2018 Nov 12.

Division of Cardiology, Clinic for Small Animal Internal Medicine, Vetsuisse Faculty University of Zürich, Winterthurerstrasse 260, CH-8057 Zürich, Switzerland. Electronic address:

Arrhythmias can complicate cardiac disease in cats and are a potential cause of sudden death. The aim of this study was to evaluate the presence and nature of cardiac arrhythmias, and the potential correlation between plasma serum troponin I (cTnI) concentrations and the presence or severity of arrhythmias in cats with decompensated (dHCM) and compensated hypertrophic cardiomyopathy (cHCM). Forty one client-owned cats were studied: 16 with cHCM, 15 with dHCM and 10 healthy control cats. Read More

Indian Heart J 2018 Dec 21;70 Suppl 3:S483-S485. Epub 2018 Aug 21.

Cardiologist, Holy Family Hospital & Research Center, Mumbai, India. Electronic address:

Use of atrial pacing has been known, yet underutilized tool for effective temporary pacing whenever needed early after cardiac surgery. The reasons may be frequent failures of epicardial wires (fixed over atria intra-operative) leading to loss of capture. Endocardial atrial pacing sites for temporary pacing are unstable and hence continuous pacing with acceptable thresholds is impossible. Read More

Egypt Heart J 2018 Dec 22;70(4):301-306. Epub 2018 Jun 22.

Prince Sultan Cardiac Centre, Military hospital, Riyadh, Saudi Arabia.

Introduction: Idiopathic short-coupled ventricular tachyarrhythmias make up a considerable proportion of ventricular tachyarrhythmias in structurally normal hearts and are the cause of 5-10% of unexpected sudden cardiac deaths. There is disparity in the literature regarding their description and a lack of formal diagnostic criteria to define them.

Objective: To validate ECG indices for the diagnosis of these ventricular tachyarrythmias and to subsequently unify their differing descriptions in the literature under a new terminology: . Read More

Europace 2018 Dec 24. Epub 2018 Dec 24.

Department of Cardiology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, Japan.

Circulation 2019 Mar;139(12):1507-1516

Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas (D.A.M., N.A., M.S.L., S.S., B.D.L.).

Background: Moderate intensity exercise is associated with a decreased incidence of atrial fibrillation. However, extensive training in competitive athletes is associated with an increased atrial fibrillation risk. We evaluated the effects of 24 months of high intensity exercise training on left atrial (LA) mechanical and electric remodeling in sedentary, healthy middle-aged adults. Read More

HeartRhythm Case Rep 2018 Dec 11;4(12):584-588. Epub 2018 Sep 11.

Division of Cardiology, Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.

Heart Rhythm 2018 Dec 18. Epub 2018 Dec 18.

Department of Physiology & Biophysics, Virginia Commonwealth University, Richmond, Virginia. Electronic address:

J Cardiovasc Electrophysiol 2019 Apr 6;30(4):487-492. Epub 2019 Jan 6.

Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Background: Epidemiological evidence has shown an association between ambient fine particulate matter (PM2.5) exposure and cardiovascular mortality. Increased ventricular premature complex (VPC) burden can cause left ventricular dilatation and dysfunction. Read More

J Nippon Med Sch 2018 ;85(6):337-342

FUJITSU LIMITED, Health Promotion Unit.

Background: Premature ventricular contractions (PVCs) are often found in healthy workers at medical checkups. In this study, we aimed to investigate the frequency of PVCs recorded during medical checkups in Japanese office workers without heart disease or other known contributing factors.

Methods: Participants in this study were 17,641 office workers, who underwent an electrocardiogram examination during a regular medical checkup between April 1 2015 and March 31 2016 and had no known heart disease. Read More

Medicine (Baltimore) 2018 Dec;97(50):e13629

Department of Neurology, The Second Hospital of Jilin University, Changchun, China.

Rationale: Co-occurrence of headache and arrhythmia is not rare. However, their causal relationship remains unclear. Here, we described a case of migraine-like headache relieving with pacemaker implantation. Read More

Heart Lung Circ 2019 Jan 15;28(1):123-133. Epub 2018 Oct 15.

Department of Cardiology, Westmead Hospital, Westmead Applied Research Centre, University of Sydney, Sydney, NSW, Australia. Electronic address:

Cardiac electrical storm (ES) is characterised by three or more discrete episodes of ventricular arrhythmia within 24hours, or incessant ventricular arrhythmia for more than 12hours. ES is a distinct medical emergency that portends a significant increase in mortality risk and often presages progressive heart failure. ES is also associated with psychological morbidity from multiple implanted cardioverter defibrillator (ICD) shocks and exponential health resource utilisation. Read More

Pacing Clin Electrophysiol 2019 02 2;42(2):247-256. Epub 2019 Jan 2.

Xinjiang Key Laboratory of Medical Animal Model Research, Clinical Medical Research Institute, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

Background: Transcutaneous stimulation of the auricular branch of the vagus nerve (AB-VNS) is a potentially noninvasive, inexpensive, and safe approach for vagus nerve stimulation that suppresses the induction and duration of atrial fibrillation and reduces sympathetic nerve outflow in healthy humans. Researchers have not determined whether AB-VNS affects ventricular arrhythmias.

Objective: To evaluate the antiarrhythmic effects of noninvasive AB-VNS on ventricular arrhythmias induced by myocardial infarction (MI). Read More

Heart Rhythm 2018 Dec 11. Epub 2018 Dec 11.

University Hospital Rangueil, Toulouse, France; Unité Inserm U 1048, Toulouse, France. Electronic address:

Background: The relationships between hemodynamic consequences of premature ventricular contractions (PVCs) and development of premature ventricular contraction-induced cardiomyopathy (PVC-CM) have not been investigated.

Objective: The purpose of this study was to correlate concealed mechanical bradycardia and/or postextrasystolic potentiation (PEP) to PVC-CM.

Methods: Invasive arterial pressure measurements from 17 patients with PVC-CM and 16 controls with frequent PVCs were retrospectively analyzed. Read More