6,931 results match your criteria Premature Ventricular Contraction


HRT assessment reviewed: a systematic review of Heart Rate Turbulence methodology.

Physiol Meas 2020 Jun 2. Epub 2020 Jun 2.

Mathematics, natural sciences and informatics, Technische Hochschule Mittelhessen, Giessen, Hessen, GERMANY.

Heart rate turbulence (HRT) is a biphasic reaction to a ventricular premature contraction (VPC) mainly mediated by the baroreflex. It can be used for risk stratification in different disease patterns. Despite existing standards there is a lot of variation in terms of measuring and calculating HRT, which complicates research and application. Read More

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http://dx.doi.org/10.1088/1361-6579/ab98b3DOI Listing

Ventricular Arrhythmias in the Patient with a Structurally Normal Heart.

J Innov Card Rhythm Manag 2018 Oct 15;9(10):3338-3353. Epub 2018 Oct 15.

Department of Cardiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

Ventricular arrhythmias (VAs) are among the most common cardiac rhythm disturbances encountered in clinical practice. Patients presenting with frequent ventricular ectopy or sustained ventricular tachycardia represent a challenging and worrisome clinical scenario for many practitioners because of concerning symptoms, frequent associated acute hemodynamic compromise, and the adverse prognostic implications inherent to these cases. While an underlying structural or functional cardiac abnormality, metabolic derangement, or medication toxicity is often readily apparent, many patients have no obvious underlying condition, despite a comprehensive diagnostic evaluation. Read More

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http://dx.doi.org/10.19102/icrm.2018.091004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252725PMC
October 2018

An Elusive and Deceptive Tachycardia.

J Innov Card Rhythm Manag 2017 Feb 15;8(2):2626-2627. Epub 2017 Feb 15.

Icahn School of Medicine at Mount Sinai, New York, NY.

A wide-complex tachycardia was induced with rapid atrial pacing, with intermittent ventriculoatrial block and QRS alternans. A short/negative HV interval was observed, and premature ventricular complexes resulted in the termination of the tachycardia. The findings at electrophysiology study were consistent with an antidromic re-entrant tachycardia involving a nodo-fascicular/ventricular connection. Read More

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http://dx.doi.org/10.19102/icrm.2017.080202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252649PMC
February 2017

His bundle pacing: troubleshooting during follow-up.

Herzschrittmacherther Elektrophysiol 2020 May 28. Epub 2020 May 28.

Klinik für Innere Medizin - Kardiologie, Diabetologie & Nephrologie, Evangelisches Klinikum Bethel, Burgsteig 13, 33617, Bielefeld, Germany.

Follow-up of pacemaker systems for His bundle pacing (HBP) requires electrocardiogram (ECG) knowledge and creative thinking. This relates to ventricular threshold measurement in which it can be difficult to distinguish between selective HBP and loss of capture with pseudofusion since, by definition, intrinsic QRS complexes and those selectively paced via the His bundle look identical. Threshold testing in HBP is best performed in unipolar pacing mode, recording of a 12-lead ECG and pacing in VVI mode significantly above the intrinsic rate. Read More

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http://dx.doi.org/10.1007/s00399-020-00693-9DOI Listing

QRS Morphology in Lead V1 for the Rapid Localization of Idiopathic Ventricular Arrhythmias Originating from The Left Ventricular Papillary Muscles: A Novel Electrocardiographic Criterion.

Heart Rhythm 2020 May 23. Epub 2020 May 23.

Division of Cardiology, Electrophysiology Section, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

Background: 12-lead electrocardiogram (ECG) criteria have been developed to identify idiopathic ventricular arrhythmias (VAs) from the left ventricular (LV) papillary muscles (PAPs), but accurate localization remains a challenge.

Objective: To develop ECG criteria for accurate localization of LV PAP VAs utilizing lead V1 exclusively.

Methods: Consecutive patients undergoing mapping and ablation of VAs from the LV PAPs guided by intracardiac echocardiography from 2007-2018 were reviewed (study group). Read More

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http://dx.doi.org/10.1016/j.hrthm.2020.05.021DOI Listing

Procedural outcomes and learning curve of cardiac arrhythmias catheter ablation using remote magnetic navigation: Experience from a large-scale single-center study.

Clin Cardiol 2020 May 26. Epub 2020 May 26.

Department of Cardiology, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background: Remote magnetic navigation (RMN)-guided ablation has become an inspiring method of catheter ablation for tachyarrhythmias.

Hypothesis: Data from a large-scale single center may provide further insight into the safety of and the learning curve for RMN-guided ablation.

Methods: A total of 1003 catheter ablation procedures using RMN for conditions including supraventricular ventricular tachycardia, atrial tachyarrhythmias, and premature ventricular contraction/ventricular tachycardia (PVC/VT) were retrospectively analyzed from an ablation registry. Read More

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http://dx.doi.org/10.1002/clc.23391DOI Listing

Investigation of the Cellular Pharmacological Mechanism and Clinical Evidence of the Multi-Herbal Antiarrhythmic Chinese Medicine Xin Su Ning.

Front Pharmacol 2020 6;11:600. Epub 2020 May 6.

Department of Traditional Chinese Medicine, Liaocheng People's Hospital, Liaocheng, China.

Xin Su Ning (XSN), a China patented and certified multi-herbal medicine, has been available in China since 2005 for treating cardiac ventricular arrhythmia including arrhythmia induced by ischemic heart diseases and viral myocarditis, without adverse reactions being reported. It is vitally important to discover pharmacologically how XSN as a multicomponent medicine exerts its clinical efficacy, and whether the therapeutic effect of XSN can be verified by standard clinical trial studies. In this paper we report our discoveries in a cellular electrophysiological study and in a three-armed, randomized, double-blind, placebo-controlled, parallel-group, multicenter trial. Read More

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http://dx.doi.org/10.3389/fphar.2020.00600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218142PMC

Inhibition of K2 and K11.1 Channels in Pigs With Left Ventricular Dysfunction.

Front Pharmacol 2020 6;11:556. Epub 2020 May 6.

Acesion Pharma, Copenhagen, Denmark.

Background: Inhibition of K2 channels, conducting I, can convert atrial fibrillation (AF) to sinus rhythm and protect against its induction. I inhibition has been shown to possess functional atrial selectivity with minor effects on ventricles. Under pathophysiological conditions with ventricular remodeling, however, inhibiting I can exhibit both proarrhythmic and antiarrhythmic ventricular effects. Read More

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http://dx.doi.org/10.3389/fphar.2020.00556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219273PMC

Response to: An alternative way to reach the ventricular surface of the sinuses of valsalva: Antegrade transseptal approach.

Authors:
Suraj Kapa

J Cardiovasc Electrophysiol 2020 May 19. Epub 2020 May 19.

Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota.

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http://dx.doi.org/10.1111/jce.14537DOI Listing

Prognostic significance of accelerated ventricular response during radiofrequency ablation of premature ventricular complexes.

Indian Pacing Electrophysiol J 2020 May 16. Epub 2020 May 16.

Unit of Cardiac Electrophysiology and Pacing, Department of Cardiology, Christian Medical College, Vellore, India. Electronic address:

Background: Accelerated ventricular response is frequently observed during radiofrequency ablation (RFA) of premature ventricular complexes (PVCs). We hypothesized that acceleration indicates an appropriate site and adequate injury to the arrhythmogenic tissue, and sought to investigate its value in predicting the outcome.

Methods: We retrospectively analyzed RFA procedures performed for PVCs in our institution from 2011 to 2019. Read More

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http://dx.doi.org/10.1016/j.ipej.2020.05.001DOI Listing

A novel ablation strategy of premature ventricular contractions originating from summit guided by CartoUNIVU module.

Clin Cardiol 2020 May 19. Epub 2020 May 19.

Department of Cardiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.

Background: Premature ventricular contractions (PVCs) from left ventricular (LV) summit remain challenging for the risk of coronary artery injury. Computed tomographic or intracardiac echocardiography may be helpful, but both still have many limitations. CartoUNIVU module has rarely been used in PVC ablation. Read More

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http://dx.doi.org/10.1002/clc.23390DOI Listing

Acute effect of outflow tract premature ventricular complex ablation on QT dispersion, Tp-e interval and Tp-e/QT ratio.

Acta Cardiol 2020 May 14:1-5. Epub 2020 May 14.

Department of Cardiology, Marmara University School of Medicine, Istanbul, Turkey.

There is limited data regarding the effect of idiopathic premature ventricular complexes (PVC) on myocardial repolarisation. Most of PVC's originate from right and left ventricular outflow tracts (RVOT and LVOT). The aim of this study is to evaluate the acute effect of outflow tract PVC ablation on electrocardiographic repolarisation markers. Read More

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http://dx.doi.org/10.1080/00015385.2020.1761595DOI Listing
May 2020
0.561 Impact Factor

Increased heart rate due to supra-ventricular tachycardia triggering premature ventricular contraction.

J Cardiovasc Electrophysiol 2020 Jun 15;31(6):1544-1546. Epub 2020 May 15.

LIRYC, University of Bordeaux, CHU de Bordeaux, Bordeaux, France.

We describe a case wherein the presence of premature ventricular contractions was related to an increased heart rate that occurred due to supra-ventricular tachycardia: atrial tachycardia or atrioventricular nodal reentry tachycardia. Read More

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http://dx.doi.org/10.1111/jce.14533DOI Listing

Novel electrocardiographic criteria for diagnosis of premature ventricular complexes arising from the base of left ventricle.

J Electrocardiol 2020 Apr 23;60:148-150. Epub 2020 Apr 23.

Department of Cardiology, Indiana University School of Medicine, Indianapolis, IN, United States of America; Roudebush Veterans Affairs Medical Center, Indianapolis, IN, United States of America.

Purpose: We report new electrocardiographic criteria (ECG) for localizing premature ventricular complexes (PVCs) originating from the base of the left ventricle (LV).

Methods: QRS deflection (positive negative or negative positive) in lead aVR and aVL respectively, were evaluated in 41 PVC/VT cases.

Results: There were a total of 41 patients, age 64 ± 11 years. Read More

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http://dx.doi.org/10.1016/j.jelectrocard.2020.04.013DOI Listing
April 2020
1.363 Impact Factor

Ablation of Refractory Papillary Muscle Ventricular Tachycardia Warranting Multiple Adjunctive Ablation Techniques: A Combined Approach for Success.

J Innov Card Rhythm Manag 2020 Feb 15;11(2):3997-4003. Epub 2020 Feb 15.

Division of Cardiac Electrophysiology, Texas Heart Institute, Houston, TX, USA.

A 27-year-old male presented to our institution with recurrent unifocal premature ventricular contraction/nonsustained ventricular tachycardia (VT) with associated cardiomyopathy. The patient had undergone three prior ablation procedures with continued arrhythmia. Mapping led to identification of the VT arising from the basal aspect of the left ventricular anterolateral papillary muscle. Read More

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http://dx.doi.org/10.19102/icrm.2020.110206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192147PMC
February 2020

The Efficacy and Safety of Radiofrequency Catheter Ablation for Cardiac Arrhythmias in Pediatric Patients.

Heart Surg Forum 2020 03 11;23(2):E114-E117. Epub 2020 Mar 11.

Department of Paediatrics, Renmin Hospital of Wuhan University, Wuhan, China.

Background: We aimed to evaluate the acute and long-term efficacy and safety of radiofrequency catheter ablation (RFCA) in Chinese pediatric patients with arrhythmias.

Methods: We gathered clinical data from pediatric patients who underwent RFCA in several large medical centers in China between 2000 and 2019.

Results: A total of 4,622 different substrates in 4,622 patients were ablated, with the majority consisting of supraventricular tachycardia (N = 3,831, 82. Read More

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http://dx.doi.org/10.1532/hsf.2837DOI Listing

Contact versus non-contact guided ablation of the right ventricular outflow tract arrhythmias: A propensity score matched analysis.

Pacing Clin Electrophysiol 2020 May 3. Epub 2020 May 3.

Division of Cardiology, Section of Pacing and Electrophysiology, Jiangsu Province Hospital and the First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

Background: There are unique advantages and disadvantages in the choice of contact mapping (CM) versus non-contact mapping (NCM) systems during ablation of right ventricular outflow tract (RVOT) arrhythmias. This study compared acute procedural success and clinical outcomes in matched patients undergoing CM versus NCM-guided RVOT ablation.

Methods: 167 consecutive patients with idiopathic RVOT VA underwent NCM or CM-guided ablation. Read More

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http://dx.doi.org/10.1111/pace.13935DOI Listing

Early clinical experience of radiofrequency catheter ablation using an audiovisual telesupport system.

Heart Rhythm 2020 May;17(5 Pt B):870-875

Department of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

Background: An audiovisual telesupport system that enables real-time audiovisual communications between 2 long-distance hospitals is one method of telemedicine. The usefulness and safety of radiofrequency catheter ablation (RFCA) using an audiovisual telesupport system has not been well established.

Objective: The purpose of this study was to evaluate the effectiveness and safety of RFCA using an audiovisual telesupport system. Read More

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http://dx.doi.org/10.1016/j.hrthm.2020.01.018DOI Listing

Chinese Herbal Medicine Dingji Fumai Decoction for Ventricular Premature Contraction: A Real-World Trial.

Biomed Res Int 2020 9;2020:5358467. Epub 2020 Apr 9.

College of Integrated Traditional Chinese and Western Medicine Hospital (T.C.M.) Affiliated to Southwest Medical University, Luzhou, China.

Background: Chinese herbal medicine Dingji Fumai Decoction (DFD) is widely clinically used for ventricular premature contraction (VPC). This real-word trial was designed to assess the safety and effectiveness of DFD for VPC.

Methods: This was a double-blinded, randomized placebo-controlled trial. Read More

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http://dx.doi.org/10.1155/2020/5358467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171618PMC

Anatomical Approach With Bipolar Ablation Between the Left Pulmonic Cusp and the Left Ventricular Outflow Tract for Left Ventricular Summit Arrhythmias.

Heart Rhythm 2020 Apr 26. Epub 2020 Apr 26.

St. Joseph's Heart Rhythm Center, Rzeszów, Poland; Department of Cardiology, Medical Centre of Postgraduate Education, Grochowski Hospital, Warsaw, Poland.

Background: Radiofrequency ablation (RFA) of ventricular arrhythmias (VAs) arising from the inaccessible basal region of the left ventricular summit (LVS) is challenging due to proximity to coronary vessels, epicardial fat and poor RF delivery within the distal coronary venous system.

Objective: We describe the outcomes of an anatomical approach for inaccessible LVS-VAs using bipolar RF (Bi-RFA) delivered from the anatomically adjacent left pulmonic cusp (LPC) to the opposite LV outflow tract (LVOT).

Methods: From 3 centers we reviewed patients (pts) who underwent Bi-RFA for inaccessible LVS-VAs refractory to conventional RFA using an anatomical approach targeting the adjacent LPC ("reversed U" approach) with catheter tip pointing inferiorly within the LPC and LVOT. Read More

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http://dx.doi.org/10.1016/j.hrthm.2020.04.029DOI Listing

Exercise-Induced Premature Ventricular Contractions Are Associated With Myocardial Ischemia Among Asymptomatic Adult Male Firefighters: Implications for Enhanced Risk Stratification.

Biol Res Nurs 2020 Apr 28:1099800420921944. Epub 2020 Apr 28.

University of Rochester School of Nursing, NY, USA.

Background: Exercise-induced premature ventricular contractions (EI-PVCs) are associated with an increased risk of cardiovascular disease among asymptomatic adult males, but the underlying mechanisms remain understudied. Myocardial ischemia due to cardiovascular disease reduces coronary blood flow, may impair exercise performance, and initiates EI-PVCs; thus, EI-PVCs may be an early indicator of cardiovascular disease.

Objective: The objective of this study was to determine whether EI-PVCs are associated with myocardial ischemia and reduced exercise performance among asymptomatic adult firefighters. Read More

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http://dx.doi.org/10.1177/1099800420921944DOI Listing

Evaluation and Management of Premature Ventricular Complexes.

Authors:
Gregory M Marcus

Circulation 2020 Apr 27;141(17):1404-1418. Epub 2020 Apr 27.

Electrophysiology Section, Division of Cardiology, University of California, San Francisco.

Premature ventricular complexes (PVCs) are extremely common, found in the majority of individuals undergoing long-term ambulatory monitoring. Increasing age, a taller height, a higher blood pressure, a history of heart disease, performance of less physical activity, and smoking each predict a greater PVC frequency. Although the fundamental causes of PVCs remain largely unknown, potential mechanisms for any given PVC include triggered activity, automaticity, and reentry. Read More

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.042434DOI Listing

Risk stratification in patients with nonischemic cardiomyopathy and ventricular arrhythmias based on quantification of intramural delayed enhancement on cardiac magnetic resonance imaging.

J Cardiovasc Electrophysiol 2020 Apr 23. Epub 2020 Apr 23.

Division of Cardiovascular Medicine and Radiology, University of Michigan, Ann Arbor, Michigan.

Introduction: Intramural scarring is a risk factor for sudden cardiac death. The objective of this study was to determine the value of scar quantification for risk stratification in patients with nonischemic cardiomyopathy (NICM) undergoing ablation procedures for ventricular arrhythmias (VA).

Methods And Results: Cardiac late gadolinium-enhanced magnetic resonance imaging was performed in patients with NICM referred for ablation of premature ventricular complexes or ventricular tachycardia (VT). Read More

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http://dx.doi.org/10.1111/jce.14514DOI Listing

Predictors of Ventricular Dysrhythmias in Neurology Intensive Care Unit Patients with Prolonged QTc.

Neurocrit Care 2020 Apr 17. Epub 2020 Apr 17.

Department of Neurology, Section of Neurocritical Care, Wake Forest School of Medicine, Medical Center Blvd, Winston-Salem, NC, 27157, USA.

Introduction: Acute neurological injury and several medications commonly administered in the Neuro ICU pose a risk of fatal cardiac dysrhythmias. The objective of this study is to identify the predictors of ventricular dysrhythmias in the Neuro ICU patients with prolonged QTc, thereby helping the clinicians make important treatment decisions.

Methods: We performed a retrospective review of all consecutive adults admitted to the Neuro ICU from January 2015 to September 2015 with a QTc interval ≥ 450 ms on electrocardiogram. Read More

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http://dx.doi.org/10.1007/s12028-020-00954-yDOI Listing

Ablation at Right Coronary Cusp as an Alternative and Favorable Approach to Eliminate Premature Ventricular Complexes Originating From the Proximal Left Anterior Fascicle.

Circ Arrhythm Electrophysiol 2020 May 17;13(5):e008173. Epub 2020 Apr 17.

Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, China (S.C., X.L., S.P., G.Z., Z.L., Y.W., K.Y., W.F., L.C., J.X., S.L.).

Background: Premature ventricular complex (PVC) with narrow QRS duration originating from proximal left anterior fascicle (LAF) is challenging for ablation. This study was performed to evaluate the safety and feasibility of ablation from right coronary cusp (RCC) for proximal LAF-PVC and to investigate this PVC's characteristics.

Methods: Mapping at RCC and left ventricle and ECG analysis were performed in 20 patients with LAF-PVC. Read More

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http://dx.doi.org/10.1161/CIRCEP.119.008173DOI Listing

Dietary and Lifestyle Patterns are Associated with Heart Rate Variability.

J Clin Med 2020 Apr 14;9(4). Epub 2020 Apr 14.

Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via Loredan, 18, 35131 Padova, Italy.

Assessment of heart rate variability (HRV) and cardiac ectopic beats is a clinically relevant topic. The present exploratory observational study aimed to inspect the relationships of lifestyle, dietary patterns, and anthropometrics with HRV, premature ventricular complexes (PVCs), and supraventricular premature complexes (SVPCs). A cross-sectional study enrolling subjects undergoing Holter monitoring was performed. Read More

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http://dx.doi.org/10.3390/jcm9041121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230664PMC

Tp-Te interval and Tp-Te/QT ratio may be predictive of idiopathic ventricular tachycardia in patients with frequent outflow tract premature ventricular complexes.

Acta Cardiol 2020 Apr 14:1-6. Epub 2020 Apr 14.

Kartal Kosuyolu Training and Research Hospital, Cardiology Clinic, Istanbul, Turkey.

The aim of present study is to evaluate the predictive value of QTc dispersion, Tp-Te interval and Tp-Te/QT ratio for idiopathic monomorphic outflow tract ventricular tachycardia (VT) occurrence in patients with frequent idiopathic outflow tract premature ventricular complexes (PVCs). A total of 180 patients (49.2 ± 13. Read More

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http://dx.doi.org/10.1080/00015385.2020.1751958DOI Listing
April 2020
0.561 Impact Factor

Catheter Ablation in Patients With Cardiogenic Shock and Refractory Ventricular Tachycardia.

Circ Arrhythm Electrophysiol 2020 May 12;13(5):e007669. Epub 2020 Apr 12.

Cardiovascular Medicine (O.M.W., K.G.T., W.I.S., M.K., M.D., M.B., B.B., T.J.D., T.D.C., D.J.C., J.R., D.O.M., N.V., M.J.N., M.K.C., P.J.T., B.D.L., A.A.H.), Cleveland Clinic, OH.

Background: There is paucity of data regarding radiofrequency ablation for ventricular tachycardia (VT) in patients with cardiogenic shock and concomitant VT refractory to antiarrhythmic drugs on mechanical support.

Methods: Patients undergoing VT ablation at our center were enrolled in a prospectively maintained registry and screened for the current study (2010-2017).

Results: All 21 consecutive patients with cardiogenic shock and concomitant refractory ventricular arrhythmia undergoing bailout ablation due to inability to wean off mechanical support were included. Read More

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http://dx.doi.org/10.1161/CIRCEP.119.007669DOI Listing

Non-invasive electroanatomic mapping to reduce mapping time during catheter ablation of outflow tract ventricular premature depolarizations.

J Interv Card Electrophysiol 2020 Apr 13. Epub 2020 Apr 13.

Department of Cardiac Electrophysiology, Northwell Health-Lenox Hill Heart and Lung, 100 East 77th Street, New York, NY, 10075, USA.

Purpose: Ventricular premature depolarizations (VPD) commonly arise from the septal anterior right ventricular outflow tract (sRVOT), the left coronary cusp (LCC), and the distal great cardiac vein (dGCV), and share common ECG characteristics. To assess the diagnostic accuracy of non-invasive electroanatomic mapping (NIEAM) in differentiating VPD origin between sRVOT, LCC and dGCV and quantify its clinical utility in eliminating unnecessary mapping and ablation.

Methods: ECGs and NIEAMs (CardioInsight, Medtronic) from 32 patients (56. Read More

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http://dx.doi.org/10.1007/s10840-020-00731-zDOI Listing

A retrospective study of immune checkpoint inhibitor-associated myocarditis in a single center in China.

Chin Clin Oncol 2020 Apr 7;9(2):16. Epub 2020 Apr 7.

Department of Radiotherapy, The First Affiliated Hospital of Nanjing Medical College, Nanjing 210029, China.

Objective: Immune checkpoint inhibitor (ICI)-associated myocarditis is a rare and potentially fatal immune-related adverse event (irAE). The study aimed to observe the occurrence of myocarditis caused by ICIs.

Methods: The clinical manifestations, diagnosis, and treatment of immune myocarditis were explored through retrospective analysis of the detailed data of typical ICI-associated myocarditis from our center and a literature review. Read More

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http://dx.doi.org/10.21037/cco.2020.03.08DOI Listing

Bipolar radiofrequency catheter ablation between the left ventricular endocardium and great cardiac vein for refractory ventricular premature complexes originating from the left ventricular summit.

J Arrhythm 2020 Apr 14;36(2):363-366. Epub 2020 Feb 14.

Department of Cardiology Tokyo Metropolitan Hiroo Hospital Tokyo Japan.

Ablation for ventricular arrhythmias originating from the left ventricular (LV) summit is sometimes challenging. Bipolar radiofrequency catheter ablation (RFCA) is effective for refractory arrhythmias; little is known about bipolar RFCA from the coronary venous system and the appropriate settings. We experienced three cases of ventricular premature complexes (VPCs) originating from the LV summit successfully treated by bipolar RFCA between the LV endocardium (irrigated catheters as active electrodes) and coronary venous system (8-mm-tip catheters as return electrodes). Read More

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http://dx.doi.org/10.1002/joa3.12312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132175PMC

Localization of origins of premature ventricular contraction in the whole ventricle based on machine learning and automatic beat recognition from 12-lead ECG.

Physiol Meas 2020 Apr 6. Epub 2020 Apr 6.

Department of Cardiolog, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, CHINA.

Background: The localization of origins of premature ventricular contraction (PVC) is the key factor for the success of ablation of ventricular arrhythmias. Existing methods rely heavily on manual extraction of PVC beats, which limits their application to the automatic PVC recognition from long-term data recorded by ECG monitors before and during operation. Besides, researches identifying PVC sources in the whole ventricle have not been reported. Read More

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http://dx.doi.org/10.1088/1361-6579/ab86d7DOI Listing

Clinical Significance of Statistical Differences.

Arq Bras Cardiol 2020 02;114(2):281-283

Hospital dos Servidores do Estado, Cardiologia, Rio de Janeiro, RJ - Brazil.

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http://dx.doi.org/10.36660/abc.20200006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077560PMC
February 2020

Noninvasive localization of cardiac arrhythmias using electromechanical wave imaging.

Sci Transl Med 2020 Mar;12(536)

Division of Cardiology, Department of Medicine and Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

Cardiac arrhythmias are a major cause of morbidity and mortality worldwide. The 12-lead electrocardiogram (ECG) is the current noninvasive clinical tool used to diagnose and localize cardiac arrhythmias. However, it has limited accuracy and is subject to operator bias. Read More

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http://dx.doi.org/10.1126/scitranslmed.aax6111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234276PMC

Characteristics and usefulness of unintended premature ventricular contraction during invasive assessment of aortic stenosis.

Int J Cardiol 2020 Feb 28. Epub 2020 Feb 28.

Institut Universitaire de Cardiologie et de Pneumologie, Université Laval, Québec, Canada. Electronic address:

Background: Postextrasystolic potentiation (PESP)-associated augmentation in left ventricular-aorta pressure gradient (LVAoG) observed after incidental premature ventricular contraction (PVC) during resting echocardiography is similar to dobutamine stress echocardiography (DSE)-associated augmentation in LVAoG in patients with low-flow, low-gradient (LF-LG) aortic stenosis (AS). What is not known is whether a similar relationship exists when unintended PVC causes PESP during cardiac catheterization in patients with AS.

Methods: We retrospectively reviewed all catheterizations performed for patients with at least moderate AS who had LVAoG assessment. Read More

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http://dx.doi.org/10.1016/j.ijcard.2020.02.053DOI Listing
February 2020

Anxiety is associated with increased risk for atrial cardiopathy.

Acta Neurol Belg 2020 Mar 19. Epub 2020 Mar 19.

Division of Neurology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300#, Nanjing, China.

Anxiety is common in patients with atrial fibrillation (AF). The mutual causal effect between anxiety and AF is expected with limited evidence. Atrial cardiopathy is a term to describe structural or electrophysiological atrium abnormality that precedes the onset of AF. Read More

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http://dx.doi.org/10.1007/s13760-020-01335-0DOI Listing

Accurate Conduction Velocity Maps and Their Association With Scar Distribution on Magnetic Resonance Imaging in Patients With Postinfarction Ventricular Tachycardias.

Circ Arrhythm Electrophysiol 2020 Apr 19;13(4):e007792. Epub 2020 Mar 19.

Alliance for Cardiovascular Diagnostic and Treatment Innovation, Johns Hopkins University (K.N.A., R.L.A., A.P., J.B.H., J.L., F.T., N.A.T.).

Background: Characterizing myocardial conduction velocity (CV) in patients with ischemic cardiomyopathy (ICM) and ventricular tachycardia (VT) is important for understanding the patient-specific proarrhythmic substrate of VTs and therapeutic planning. The objective of this study is to accurately assess the relation between CV and myocardial fibrosis density on late gadolinium-enhanced cardiac magnetic resonance imaging (LGE-CMR) in patients with ICM.

Methods: We enrolled 6 patients with ICM undergoing VT ablation and 5 with structurally normal left ventricles (controls) undergoing premature ventricular contraction or VT ablation. Read More

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http://dx.doi.org/10.1161/CIRCEP.119.007792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196439PMC

Catheter cryoablation of ventricular ectopy originating from his region.

Clin Case Rep 2020 Mar 5;8(3):487-490. Epub 2020 Feb 5.

The Arrhythmology Unit Department of Invasive Cardiology Fondazione "Gabriele Monasterio" CNR-Regione Toscana Pisa Italy.

Careful mapping, early detection of AV conduction damage and cryothermal energy availability are essential in dealing with ablation procedures at the parahisian region. Read More

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http://dx.doi.org/10.1002/ccr3.2649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069889PMC

Premature ventricular contraction detection for long-term monitoring in an implantable cardiac monitor.

Pacing Clin Electrophysiol 2020 May 10;43(5):462-470. Epub 2020 Apr 10.

Medtronic Inc, Mounds View, Minnesota.

Background: Premature ventricular complexes (PVCs) are an important therapeutic target in symptomatic patients and in the setting of PVC-induced cardiomyopathy; however, measuring burden and therapeutic response is challenging. We developed and validated an algorithm for continuous long-term monitoring of PVC burden in an insertable cardiac monitor (ICM).

Methods: A high-specificity PVC detection algorithm was developed using real-world ICM data and validated using simultaneous Holter data and real-world ICM data. Read More

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http://dx.doi.org/10.1111/pace.13903DOI Listing

Electrocardiographic characteristics for successful radiofrequency ablation of right coronary cusp premature ventricular contractions.

Medicine (Baltimore) 2020 Mar;99(11):e19398

Division of Cardiology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan university School of Medicine, Seoul, Republic of Korea.

Electrocardiographic (ECG) criteria identifying right- and left-sided outflow tract origins have been established. The purpose of this study was to define the criteria for premature ventricular contractions (PVCs) originating from the right coronary cusp (RCC) adequately.We analyzed ECG and electrophysiologic study data from patients who underwent successful ablation of PVCs originating from the RCC and right ventricular outflow tract (RVOT). Read More

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http://dx.doi.org/10.1097/MD.0000000000019398DOI Listing
March 2020
5.723 Impact Factor

Bepridil Inhibits Premature Ventricular Complexes Induced by Cardio-Sympathetic Nerve Stimulation in a Canine Experimental Model.

Int Heart J 2020 Mar 14;61(2):338-346. Epub 2020 Mar 14.

Cardiovascular Research, Graduate School of Health Sciences, Niigata University School of Medicine.

Sympathetic nerve activity has arrhythmogenic potential for ventricular arrhythmias associated with structural heart diseases. However, a sufficient amount of beta-blockers occasionally cannot be prescribed in some patients.An experimental study was performed to clarify the therapeutic effects of bepridil, a multiple ionic current inhibitor that does not affect beta-adrenergic receptors, for premature beats occurring during enhanced sympathetic nerve activity. Read More

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http://dx.doi.org/10.1536/ihj.19-494DOI Listing

Successful left coronary cusp cryoablation in an adolescent with premature ventrıcular extrasystoles-associated cardiomyopathy.

Turk Kardiyol Dern Ars 2020 Mar;48(2):171-176

Department of Pediatric Cardiology, University of Health Sciences İstanbul Mehmet Akif Ersoy Thoracic and Cardiovasculer Surgery Training and Research Hospital, İstanbul, Turkey.

Ventricular arrhythmias arising from coronary cusps are not uncommon. However, the mapping and ablation of outflow tract ventricular arrhythmias originating from aortic cusps can be challenging. Radiofrequency ablation of this area can cause rare but serious complications. Read More

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http://dx.doi.org/10.5543/tkda.2019.25342DOI Listing

Acute, subacute and chronic sequelae of horses accidentally exposed to monensin-contaminated feed.

Equine Vet J 2020 Mar 7. Epub 2020 Mar 7.

Department of Clinical Sciences, Faculty of Veterinary Medicine, Université de Montréal, St-Hyacinthe, Quebec, Canada.

Background: Monensin is highly toxic to horses and inadvertent ingestion can result in cardiac injury and death.

Objectives: To describe sequelae of monensin ingestion and to determine clinical predictors of outcome.

Study Design: Observational clinical study. Read More

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http://dx.doi.org/10.1111/evj.13258DOI Listing

An intelligent learning approach for improving ECG signal classification and arrhythmia analysis.

Artif Intell Med 2020 03 31;103:101788. Epub 2019 Dec 31.

State Key Laboratory of Management and Control for Complex Systems, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China; School of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, China. Electronic address:

The recognition of cardiac arrhythmia in minimal time is important to prevent sudden and untimely deaths. The proposed work includes a complete framework for analyzing the Electrocardiogram (ECG) signal. The three phases of analysis include 1) the ECG signal quality enhancement through noise suppression by a dedicated filter combination; 2) the feature extraction by a devoted wavelet design and 3) a proposed hidden Markov model (HMM) for cardiac arrhythmia classification into Normal (N), Right Bundle Branch Block (RBBB), Left Bundle Branch Block (LBBB), Premature Ventricular Contraction (PVC) and Atrial Premature Contraction (APC). Read More

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http://dx.doi.org/10.1016/j.artmed.2019.101788DOI Listing

Post-extrasystolic potentiation as a predictor of premature ventricular contraction-cardiomyopathy in an animal model.

Europace 2020 May;22(5):813-820

Pauley Heart Center, Virginia Commonwealth University, Richmond, Ste. 4A-100, Richmond, VA 23249, USA.

Aims: High premature ventricular contractions (PVCs) burden does not always predict the development of PVC-cardiomyopathy (CM). We sought to evaluate post-extrasystolic potentiation (PESP) of left ventricular ejection fraction (LVEF) to predict the severity of PVC-CM in an animal model.

Methods And Results: Right ventricular apical bigeminal PVCs were introduced for 12 weeks in 11 canines to induce PVC-CM. Read More

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http://dx.doi.org/10.1093/europace/euaa025DOI Listing

Ventricular Arrhythmias in Myocarditis: Characterization and Relationships With Myocardial Inflammation.

J Am Coll Cardiol 2020 Mar;75(9):1046-1057

Department of Cardiac Electrophysiology and Arrhythmology, IRCCS San Raffaele Hospital and Vita-Salute University, Milan, Italy.

Background: Ventricular arrhythmias (VAs) have never been systematically investigated in patients with myocarditis at different stages.

Objectives: The purpose of this study was to compare baseline and follow-up characteristics of VAs in patients with active myocarditis (AM) versus previous myocarditis (PM).

Methods: A total of 185 consecutive patients (69% males, age 44 ± 15 years, left ventricular ejection fraction 49 ± 14%) with myocarditis and VA at index hospitalization, including ventricular fibrillation, ventricular tachycardia (VT), nonsustained ventricular tachycardia (NSVT), and Lown's grade ≥2 premature ventricular complexes, were enrolled. Read More

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http://dx.doi.org/10.1016/j.jacc.2020.01.036DOI Listing

A response to the letter regarding the article, "Isolated prepotential preceding a presumed idiopathic premature ventricular contraction originating from the aortomitral continuity".

J Cardiovasc Electrophysiol 2020 May 3;31(5):1237. Epub 2020 Mar 3.

Department of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.

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http://dx.doi.org/10.1111/jce.14410DOI Listing

Isolated prepotential during premature ventricular contraction at aortic cusps as a reflection of preferential conduction and successful ablation site or valvular closure artifact?

J Cardiovasc Electrophysiol 2020 May 3;31(5):1235-1236. Epub 2020 Mar 3.

Department of Cardiology, Ankara City Hospital, Health Sciences University, Ankara, Turkey.

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http://dx.doi.org/10.1111/jce.14409DOI Listing

Outflow-tract ventricular tachycardia: Can 12 lead ECG during sinus rhythm identify underlying cardiac sarcoidosis?

Indian Pacing Electrophysiol J 2020 May - Jun;20(3):83-90. Epub 2020 Feb 29.

Dept of Electrophysiology, Care Hospitals, Hyderabad, India. Electronic address:

Background: Patients with outflow tract ventricular tachycardia (OTVT) with normal echocardiogram are labeled as idiopathic VT (IVT). However, a subset of these patients is subsequently diagnosed with underlying cardiac sarcoidosis (CS).

Objective: Whether electrocardiogram (ECG) abnormalities in sinus rhythm (SR) can differentiate underlying CS from IVT. Read More

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http://dx.doi.org/10.1016/j.ipej.2020.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244880PMC
February 2020