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JACC Clin Electrophysiol 2022 Apr 28. Epub 2022 Apr 28.

Jesselson Integrated Heart Center, Shaare Zedek Medical Center, Jerusalem, Israel; Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel.

Idiopathic ventricular fibrillation is responsible for approximately 10% of cases of aborted cardiac arrest. Recent studies have shown that short-coupled ventricular premature complexes are present at the onset of idiopathic ventricular fibrillation in 6.6%-17% of patients. Read More

Front Cardiovasc Med 2022 2;9:889761. Epub 2022 May 2.

The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Coronary venous spasm has never been reported during premature ventricular extrasystole ablation. We report a 20-year-old female patient who experienced a severe spasm of the great cardiac vein during radiofrequency ablation for premature ventricular contractions, which were relieved eventually by the administration of intracoronary nitroglycerine. The operation was successfully completed, leading to a long-term resolution of her palpitation symptoms. Read More

Eur Heart J Case Rep 2022 May 16;6(5):ytac174. Epub 2022 May 16.

Sports Cardiology Department, National Olympic Academy, Tehran, Iran.

Background: Premature ventricular contractions (PVCs) are commonly observed during pre-participation cardiac screening in elite athletes. There is an ongoing debate about the clinical significance of PVCs in athletes and whether burden, morphology, or both should be used to differentiate benign PVCs from PVCs suggestive of cardiac disease.

Case Summary: A 28-year-old male athlete was evaluated as part of the pre-participation screening programme. Read More

Echocardiography 2022 May 16. Epub 2022 May 16.

Department of Cardiology, Bursa Yuksek İhtisas Training and Research Hospital, Health Sciences University, Bursa, Turkey.

Background: Consistent data from several studies have shown that catheter ablation of frequent premature ventricular complexes (PVCs) results in substantial improvement in left ventricular ejection fraction (LVEF), left ventricular diastolic function, and left atrial volume and mechanics. However, the effects of catheter ablation of PVCs on atrial electromechanical properties have not been documented yet.

Aims: In the present study, we investigated the short-term effects of radiofrequency catheter ablation (RFCA) of outflow tract PVCs on atrial electromechanical delay (EMD). Read More

Int J Cardiol Heart Vasc 2022 Jun 4;40:101042. Epub 2022 May 4.

Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein, Germany.

Objectives: We sought to assess the efficacy, safety and short-term clinical outcome of very high-power short-duration (vHP-SD) radiofrequency (RF) catheter ablation for the treatment of idiopathic PVCs originating from the cardiac outflow tract (OT).

Background: Power-controlled RF ablation is a widely used technique for the treatment of premature ventricular contractions (PVCs). A novel ablation catheter offers three microelectrodes and six thermocouples at its tip and provides temperature-controlled vHP-SD (90 Watts/4 s,) with the opportunity to switch to moderate-power mode. Read More

Front Cardiovasc Med 2022 28;9:804424. Epub 2022 Apr 28.

Cardiology Department, Regional General Hospital "F. Miulli", Bari, Italy.

Background: Awareness of radiation exposure risks associated to interventional cardiology procedures is growing. The availability of new technologies in electrophysiology laboratories has reduced fluoroscopy usage during arrhythmias ablations. The aim of this study was to describe procedures with and without X-Rays and to assess feasibility, safety, and short-term efficacy of zero fluoroscopy intervention in a high-volume center oriented to keep exposure to ionizing radiation as low as reasonably achievable. Read More

Heart Rhythm 2022 May 11. Epub 2022 May 11.

Department of Cardiology, Wuhan Asian Heart Hospital, Wuhan, China.

Background: Premature ventricular complexes (PVCs) with narrow QRS duration, inferior frontal plane QRS axis and right bundle branch block(RBBB) pattern generally originate from the proximal segment of the left anterior fascicle(LAF).

Objective: This study aimed to investigate the exact origin of this category of PVCs.

Methods: 22 patients with assumed proximal LAF-PVCs were enrolled in the present study. Read More

Ann Noninvasive Electrocardiol 2022 May 14:e12962. Epub 2022 May 14.

Department of Cardiology, Central Hospital of Shengli Oil Field, Dongying, China.

Background: This study aimed to investigate the electrophysiological characteristics of idiopathic ventricular arrhythmias (VAs) originating from the left ventricular posterior papillary muscles (LPPM) and explore the efficiency of catheter ablation using three-dimensional intracardiac ultrasound technology.

Methods: Twenty-seven cases of premature ventricular contraction/ventricular tachycardia (PVC/VT) originating from the left ventricular posterior papillary muscles were recorded from July 2015 to June 2019 in the Central Hospital of Shengli Oil Field and the First Affiliated Hospital of Zhengzhou University. Electrophysiological mapping and radiofrequency catheter ablation (RFCA) were performed using three-dimensional intracardiac ultrasound technology. Read More

Front Physiol 2022 26;13:870435. Epub 2022 Apr 26.

Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.

The clinical value of non-invasive mapping system depends on its accuracy under common variations of the inputs. The View Into Ventricular Onset (VIVO) system matches simulated QRS complexes of a patient-specific anatomical model with a 12-lead ECG to estimate the origin of ventricular arrhythmias. We aim to test the performance of the VIVO system and its sensitivity to changes in the anatomical model, time marker placement to demarcate the QRS complex and body position. Read More

Heart Vessels 2022 May 12. Epub 2022 May 12.

Semmelweis University Heart and Vascular Centre, Városmajor u. 68, Budapest, 1122, Hungary.

Comparative data are virtually missing about the performance of different electro-anatomical mapping (EAM) system platforms on outflow tract (OT) premature ventricular complex (PVC) ablation outcomes with manual ablation catheters. We aimed to compare the acute success-, complication-, and long-term recurrence rates of impedance-based (IMP) and magnetic field-based (MAG) EAM platforms in manual OT PVC ablation. Single-centre, propensity score matched data of 39-39 patients ablated for OT PVCs in 2015-17 with IMP or MAG platforms were analysed. Read More

Eur Heart J Case Rep 2022 May 17;6(5):ytac115. Epub 2022 Mar 17.

Department of Molecular Pharmacology & Experimental Therapeutics, Windland Smith Rice Sudden Death Genomics Laboratory, Mayo Clinic, Rochester, MN 55905, USA.

Background: Pathogenic variants in the lamin A/C gene (LMNA) can lead to a wide range of phenotypes from dilated and arrhythmogenic cardiomyopathies and conduction abnormalities to partial lipodystrophies. This case highlights a coincidental pathogenic LMNA variant identified in a patient with sudden cardiac arrest (SCA). We demonstrate the need for careful interpretation of pathogenic variants identified in cardiomyopathy genes by highlighting a case in which a coincidental pathogenic LMNA variant was found in a patient with premature ventricular complex (PVC)-induced ventricular fibrillation (VF). Read More

Circulation 2022 May 2;145(18):1437-1439. Epub 2022 May 2.

Department of Cardiology, University Medical Center Utrecht, The Netherlands (S.A.G., R.J.H.).

HeartRhythm Case Rep 2022 Mar 30;8(3):195-199. Epub 2021 Dec 30.

Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China.

Sleep Breath 2022 Apr 30. Epub 2022 Apr 30.

Department of Cardiology, Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People's Republic of China.

Background: Obstructive sleep apnea (OSA) is significantly associated with a higher risk of ventricular arrhythmia (VA). QT, the Tp-e/QT ratio, and QT dispersion (QTd) are used to evaluate myocardial repolarization and are highly correlated with VA. The aim was to evaluate the predictive value of the Tp-e/QT ratio and other electrocardiogram (ECG) parameters for nocturnal premature ventricular contractions (PVCs) in patients with OSA. Read More

Chin Med 2022 Apr 28;17(1):52. Epub 2022 Apr 28.

Regenerative Medicine Research Center, West China Hospital, Sichuan University, Keyuan Road 4, Gaopeng Street, Chengdu, 610041, Sichuan, China.

Background: Acupuncture at Neiguan (PC6) has long been used for treating cardiovascular diseases, but its antiarrhythmic effect and the underlying mechanisms have not yet been well investigated, especially regarding premature ventricular complexes (PVCs) that occur post-myocardial infarction (MI). The purpose of this study was to study the antiarrhythmic effect of manual acupuncture applied to PC6 for a relatively long period (28 days) and to elucidate the mechanism in mice.

Methods: An MI mouse model was generated by ligating the left anterior descending coronary artery in male C57/BL6 mice (n = 31). Read More

J ECT 2022 Apr 26. Epub 2022 Apr 26.

From the Departments of Psychiatry.

Objective: The aims of the study were to report the case of a 54-year-old man with recurrent depressive disorder with multiple medical comorbidities having a dual-chamber pacemaker, treated successfully with 11 sessions of electroconvulsive therapy, and to conduct a systematic review of published cases documenting the use of electroconvulsive therapy (ECT) in patients with cardiac implantable electronic devices (CIEDs) for treating major psychiatric disorders.

Methods: We searched electronic databases (MEDLINE, PubMed, Google Scholar, Embase, Cochrane Library, PsycINFO, and Crossref) and included studies reporting on the use of electroconvulsive therapy in patients with CIEDs.

Results: Thirty-five publications across 53 years (1967-2021) reported on 76 patients (including current report) who received a pooled total of 979 modified ECT sessions. Read More

Circ Arrhythm Electrophysiol 2022 May 27;15(5):e010020. Epub 2022 Apr 27.

Helmsley Electrophysiology Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, NY (S.R.D., C.O., T.S., W.W., J.S.K., S.C., V.Y.R.).

Background: Frequent premature ventricular contractions (PVCs) are often amenable to catheter ablation. However, a deep intramural focus may lead to failure due to inability of standard ablation techniques to penetrate the focus. We sought to assess the efficacy and safety of infusion needle ablation (INA) for PVCs that are refractory to standard radiofrequency ablation. Read More

Front Cardiovasc Med 2022 6;9:793535. Epub 2022 Apr 6.

Life Science Informatics Group, Department of Mathematics, Natural Sciences and Informatics, Technische Hochschule Mittelhessen (THM) University of Applied Sciences, Giessen, Germany.

Heart rate turbulence (HRT) is a characteristic heart rate pattern triggered by a ventricular premature contraction (VPC). It can be used to assess autonomic function and health risk for various conditions, e.g. Read More

Medicina (Kaunas) 2022 Apr 18;58(4). Epub 2022 Apr 18.

Samsung Medical Center, Division of Cardiology, Heart Vascular and Stroke Institute, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.

: The treadmill test (TMT) is a predictive tool for myocardial ischemia. Recently, exercise-provoked ventricular premature contracture (VPC) during TMT was shown to have a relation with coronary artery disease and cardiovascular mortality. Therefore, we evaluate clinical correlates of exercise-provoked VPC and compare the predictive power for myocardial ischemia and cardiovascular events. Read More

JACC Clin Electrophysiol 2022 Apr 31;8(4):526-528. Epub 2022 Jan 31.

JACC Clin Electrophysiol 2022 Apr;8(4):477-479

Cardiac Electrophysiology Section, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

J Healthc Eng 2022 12;2022:3408501. Epub 2022 Apr 12.

Biomedical Imaging and Electrophysiology Laboratory, School of Electronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, China.

Recently, cardiac arrhythmia recognition from electrocardiography (ECG) with deep learning approaches is becoming popular in clinical diagnosis systems due to its good prognosis findings, where expert data preprocessing and feature engineering are not usually required. But a lightweight and effective deep model is highly demanded to face the challenges of deploying the model in real-life applications and diagnosis accurately. In this work, two effective and lightweight deep learning models named Deep-SR and Deep-NSR are proposed to recognize ECG beats, which are based on two-dimensional convolution neural networks (2D CNNs) while using different structural regularizations. Read More

Sci Rep 2022 Apr 21;12(1):6589. Epub 2022 Apr 21.

Department of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology, Technická 12, 616 00, Brno, Czech Republic.

Accurate automated detection of P waves in ECG allows to provide fast correct diagnosis of various cardiac arrhythmias and select suitable strategy for patients' treatment. However, P waves detection is a still challenging task, especially in long-term ECGs with manifested cardiac pathologies. Software tools used in medical practice usually fail to detect P waves under pathological conditions. Read More

Biosensors (Basel) 2022 Mar 22;12(4). Epub 2022 Mar 22.

School of Instrument Science and Engineering, Southeast University, Nanjing 210096, China.

Premature ventricular contraction (PVC) is one of the common ventricular arrhythmias, which may cause stroke or sudden cardiac death. Automatic long-term electrocardiogram (ECG) analysis algorithms could provide diagnosis suggestion and even early warning for physicians. However, they are mutually exclusive in terms of robustness, generalization and low complexity. Read More

J Cardiovasc Electrophysiol 2022 Apr 20. Epub 2022 Apr 20.

Division of Cardiology, Heart Rhythm Services, University of British Columbia, Vancouver, Canada.

J Assoc Physicians India 2022 Apr;70(4):11-12

Mandya Institute of Medical Sciences, Mandya.

Acute Coronary Syndrome (ACS) is an emerging epidemic in India. Conduction blocks occur in about 15-20% of patients with acute MI, studies have shown that arrhythmias are important predictors of poor outcome in patients with ACS and are associated with higher in hospital mortality.In this study an attempt is made to know the association of arrhythmias in patients of acute MI. Read More

Eur Heart J 2022 Apr 20. Epub 2022 Apr 20.

Department of Genetics, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, The Netherlands.

Aims: Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is characterized by ventricular arrhythmias (VAs) and sudden cardiac death (SCD). We aimed to develop a model for individualized prediction of incident VA/SCD in ARVC patients.

Methods And Results: Five hundred and twenty-eight patients with a definite diagnosis and no history of sustained VAs/SCD at baseline, aged 38. Read More

J Trop Pediatr 2022 Apr;68(3)

Department of Pediatric Cardiology, Faculty of Medicine, Pamukkale University, Denizli, Turkey.

Background: Rhabdomyolysis after spider bite has been reported in a small number of patients, and myocarditis in even fewer. However, arrhythmia associated with latrodectism in children has not been described in the literature to date.

Case Summary: A girl presented approximately 4. Read More

Eur Heart J Case Rep 2022 Apr 22;6(4):ytac129. Epub 2022 Mar 22.

Division of Cardiology, Cardiovascular and Aortic Center, Saiseikai Fukuoka General Hospital, 1-3-46 Tenjin Chuo-ku, Fukuoka 810-0001, Japan.

Background: Ventricular premature complexes (VPCs) occasionally originate from the aortic sinus of Valsalva. Because the anterior part of the left coronary cusp (LCC) and right coronary cusp (RCC) are connected through the ventricular musculature at their bases, VPCs are more common in the LCC and the RCC than in the non-coronary cusp (NCC). We herein report a case in which VPCs were successfully ablated from the NCC, which is considered rare. Read More

Front Cardiovasc Med 2022 31;9:816237. Epub 2022 Mar 31.

Cardiology Division, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Background: Left anterior fascicle (LAF) premature ventricular contractions (PVC) are rarely reported. We described the electrocardiographic and electrophysiological characteristics of PVCs originating from LAF and evaluated the results of catheter ablation.

Methods: The baseline AH and HV intervals were recorded during normal sinus rhythm (NSR), and the HV interval of LAF-PVC was measured during the procedure. Read More