Search Our Scientific Publications & Authors

Heart Rhythm 2019 Feb 14. Epub 2019 Feb 14.

Centre for Heart Rhythm disorders (CHRD), South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia. Electronic address:

Background: Atrial fibrillation (AF) is common after pacemaker implantation. Nevertheless, the impact of pacemaker algorithms in AF prevention is not well understood.

Objectives: To evaluate the role of pacing algorithms in preventing AF progression. Read More

Clin Res Cardiol 2019 Feb 15. Epub 2019 Feb 15.

Semmelweis University Heart and Vascular Centre, Városmajor u. 68, Budapest, 1122, Hungary.

Objective: Patients with electrical injury are considered to be at high risk of cardiac arrhythmias. Due to the small number of studies, there is no widely accepted guideline regarding the risk assessment and management of arrhythmic complications after electrical accident (EA). Our retrospective observational study was designed to determine the prevalence of ECG abnormalities and cardiac arrhythmias after EA, to evaluate the predictive value of cardiac biomarkers for this condition and to assess in-hospital and 30-day mortality. Read More

J Diabetes 2019 Feb 15. Epub 2019 Feb 15.

Department of Endocrinology, Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, Jiangsu, China.

Background: Cardiovascular autonomic neuropathy (CAN) is a risk factor for arrhythmias and adverse cardiovascular events, but the relation between the severity of CAN progression and nocturnal arrhythmias needs to be furthermore clarified. The following study aims to evaluate the association between nocturnal arrhythmias and severity of CAN in patients with type 2 diabetes.

Methods: 219 type 2 diabetes patients were recruited from January 2017 to May 2018. Read More

Heart Lung Circ 2019 Mar;28(3):351-353

The University of Newcastle, Newcastle, NSW, Australia; Cardiovascular Department, John Hunter Hospital, Newcastle, NSW, Australia; Hunter Medical Research Institute, Newcastle, NSW, Australia. Electronic address:

Heart Rhythm 2019 Jan 30. Epub 2019 Jan 30.

The Cardiovascular Division, Department of Medicine, Vanderbilt University Medical Center, 1215 21st Avenue South, Nashville, TN, USA. Electronic address:

Background: Catheter ablation for polymorphic ventricular tachycardia and ventricular fibrillation (PMVT/VF) may target triggering premature ventricular contractions (PVCs). Targeting ventricular scar has also been suggested but data are limited.

Objective: Characterize the electrophysiologic findings and ablation outcomes for patients with PMVT/VF and structural heart disease, compared to those with idiopathic VF. Read More

Ann Cardiol Angeiol (Paris) 2019 Jan 22. Epub 2019 Jan 22.

Centre de médecine et des sciences de sport, Tunis, Tunisia.

Introduction: Premature ventricular complexes (PVC) are generally considered as a benign electrocardiographic abnormality in the athletic population. However it may be indicative of underlying heart disease which may increase the risk of sudden death. This implies the need for cardiological evaluation before indicating the ability to practice competitive sports. Read More

Sci Total Environ 2019 Mar 12;657:1285-1293. Epub 2018 Dec 12.

Department of Occupational and Environmental Health, Peking University School of Public Health, Peking University Institute of Environmental Medicine, Beijing, China; Key Laboratory of Molecular Cardiovascular Sciences of Ministry of Education, Peking University, Beijing, China. Electronic address:

Epidemiological evidence linking source-specific ambient particulate matter with aerodynamic diameter <2.5 μm (PM) and cardiac arrhythmias is limited. In this study, we investigated the impact of source-specific PM on cardiac arrhythmias in a panel of forty-five healthy adults living in Beijing, China, between 2015 and 2016. Read More

Australas Phys Eng Sci Med 2019 Jan 14. Epub 2019 Jan 14.

Department of Biomedical Systems and Informatics Engineering, Yarmouk University, Irbid, Jordan.

Electrocardiogram (ECG) beat classification is a significant application in computer-aided analysis and diagnosis technologies. This paper proposed a method to detect, extract informative features, and classify ECG beats utilizing real ECG signals available in the standard MIT-BIH Arrhythmia database, with 10,502 beats had been extracted from it. The present study classifies the ECG beat into six classes, normal beat (N), Left bundle branch block beat, Right bundle branch block beat, Premature ventricular contraction, atrial premature beat, and aberrated atrial premature, using Gaussian mixture and wavelets features, and by applying principal component analysis for feature set reduction. Read More

Comput Methods Programs Biomed 2019 Feb 27;169:59-69. Epub 2018 Dec 27.

Telecommunication and Aeronautic Engineering, São Paulo State University (UNESP), São João da Boa Vista, Brazil. Electronic address:

Background And Objective: Premature ventricular contraction is associated to the risk of coronary heart disease, and its diagnosis depends on a long time heart monitoring. For this purpose, monitoring through Holter devices is often used and computational tools can provide essential assistance to specialists. This paper presents a new premature ventricular contraction recognition method based on a simplified set of features, extracted from geometric figures constructed over QRS complexes (Q, R and S waves). Read More

Nephrol Dial Transplant 2019 Jan 9. Epub 2019 Jan 9.

Cardiorenal Translational Laboratory, Institute of Research i+12, Hospital Universitario 12 de Octubre, Madrid, Spain.

Background: Cardiac dysfunction and arrhythmia are common and onerous cardiovascular events in end-stage renal disease (ESRD) patients, especially those on dialysis. Fibroblast growth factor (FGF)-23 is a phosphate-regulating hormone whose levels dramatically increase as renal function declines. Beyond its role in phosphorus homeostasis, FGF-23 may elicit a direct effect on the heart. Read More

Heart Rhythm 2019 Jan 4. Epub 2019 Jan 4.

Heart Rhythm Center, Centro Cardiologico Monzino IRCCS, Milan, Italy; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

Background: The effectiveness of radiofrequency catheter ablation (RFCA) in atrial tachyarrhythmias correlates with lesion transmurality. Ablation Index (AI) is an index that incorporates contact force, time, and radiofrequency power simultaneously and is able to predict lesion size and outcomes in RFCA of atrial fibrillation.

Objective: The purpose of this study was to assess whether AI could be an acute and long-term success predictor in RFCA of premature ventricular complexes (PVCs). Read More

Vet J 2019 Jan 12;243:21-25. Epub 2018 Nov 12.

Division of Cardiology, Clinic for Small Animal Internal Medicine, Vetsuisse Faculty University of Zürich, Winterthurerstrasse 260, CH-8057 Zürich, Switzerland. Electronic address:

Arrhythmias can complicate cardiac disease in cats and are a potential cause of sudden death. The aim of this study was to evaluate the presence and nature of cardiac arrhythmias, and the potential correlation between plasma serum troponin I (cTnI) concentrations and the presence or severity of arrhythmias in cats with decompensated (dHCM) and compensated hypertrophic cardiomyopathy (cHCM). Forty one client-owned cats were studied: 16 with cHCM, 15 with dHCM and 10 healthy control cats. Read More

Indian Heart J 2018 Dec 21;70 Suppl 3:S483-S485. Epub 2018 Aug 21.

Cardiologist, Holy Family Hospital & Research Center, Mumbai, India. Electronic address:

Use of atrial pacing has been known, yet underutilized tool for effective temporary pacing whenever needed early after cardiac surgery. The reasons may be frequent failures of epicardial wires (fixed over atria intra-operative) leading to loss of capture. Endocardial atrial pacing sites for temporary pacing are unstable and hence continuous pacing with acceptable thresholds is impossible. Read More

Egypt Heart J 2018 Dec 22;70(4):301-306. Epub 2018 Jun 22.

Prince Sultan Cardiac Centre, Military hospital, Riyadh, Saudi Arabia.

Introduction: Idiopathic short-coupled ventricular tachyarrhythmias make up a considerable proportion of ventricular tachyarrhythmias in structurally normal hearts and are the cause of 5-10% of unexpected sudden cardiac deaths. There is disparity in the literature regarding their description and a lack of formal diagnostic criteria to define them.

Objective: To validate ECG indices for the diagnosis of these ventricular tachyarrythmias and to subsequently unify their differing descriptions in the literature under a new terminology: . Read More

Europace 2018 Dec 24. Epub 2018 Dec 24.

Department of Cardiology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, Japan.

HeartRhythm Case Rep 2018 Dec 11;4(12):584-588. Epub 2018 Sep 11.

Division of Cardiology, Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.

Heart Rhythm 2018 Dec 18. Epub 2018 Dec 18.

Department of Physiology & Biophysics, Virginia Commonwealth University, Richmond, Virginia. Electronic address:

J Cardiovasc Electrophysiol 2018 Dec 21. Epub 2018 Dec 21.

Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Background: Epidemiological evidence has shown an association between ambient fine particulate matter (PM2.5) exposure and cardiovascular mortality. Increased ventricular premature complex (VPC) burden can cause left ventricular dilatation and dysfunction. Read More

Medicine (Baltimore) 2018 Dec;97(50):e13629

Department of Neurology, The Second Hospital of Jilin University, Changchun, China.

Rationale: Co-occurrence of headache and arrhythmia is not rare. However, their causal relationship remains unclear. Here, we described a case of migraine-like headache relieving with pacemaker implantation. Read More

Heart Lung Circ 2019 Jan 15;28(1):123-133. Epub 2018 Oct 15.

Department of Cardiology, Westmead Hospital, Westmead Applied Research Centre, University of Sydney, Sydney, NSW, Australia. Electronic address:

Cardiac electrical storm (ES) is characterised by three or more discrete episodes of ventricular arrhythmia within 24hours, or incessant ventricular arrhythmia for more than 12hours. ES is a distinct medical emergency that portends a significant increase in mortality risk and often presages progressive heart failure. ES is also associated with psychological morbidity from multiple implanted cardioverter defibrillator (ICD) shocks and exponential health resource utilisation. Read More

Pacing Clin Electrophysiol 2019 Feb 2;42(2):247-256. Epub 2019 Jan 2.

Xinjiang Key Laboratory of Medical Animal Model Research, Clinical Medical Research Institute, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

Background: Transcutaneous stimulation of the auricular branch of the vagus nerve (AB-VNS) is a potentially noninvasive, inexpensive, and safe approach for vagus nerve stimulation that suppresses the induction and duration of atrial fibrillation and reduces sympathetic nerve outflow in healthy humans. Researchers have not determined whether AB-VNS affects ventricular arrhythmias.

Objective: To evaluate the antiarrhythmic effects of noninvasive AB-VNS on ventricular arrhythmias induced by myocardial infarction (MI). Read More

Heart Rhythm 2018 Dec 11. Epub 2018 Dec 11.

University Hospital Rangueil, Toulouse, France; Unité Inserm U 1048, Toulouse, France. Electronic address:

Background: The relationships between hemodynamic consequences of premature ventricular contractions (PVCs) and development of premature ventricular contraction-induced cardiomyopathy (PVC-CM) have not been investigated.

Objective: The purpose of this study was to correlate concealed mechanical bradycardia and/or postextrasystolic potentiation (PEP) to PVC-CM.

Methods: Invasive arterial pressure measurements from 17 patients with PVC-CM and 16 controls with frequent PVCs were retrospectively analyzed. Read More

J Am Coll Cardiol 2018 Dec;72(23 Pt A):2870-2882

Section of Cardiac Electrophysiology, Department of Medicine, University of California-San Francisco, San Francisco, California. Electronic address:

Background: The pathophysiology of cardiomyopathy associated with premature ventricular contractions (PVCs) remains unclear.

Objectives: This study prospectively explored cardiomyopathy development in a swine model of paced ectopic beats.

Methods: A total of 35 swine underwent pacemaker implantation. Read More

J Vet Intern Med 2019 Jan 11;33(1):54-63. Epub 2018 Dec 11.

Clinic of Small Animal Medicine, LMU University, Munich, Germany.

Background: Echocardiography and 24-hour ECG are the gold standard tests to diagnose dilated cardiomyopathy (DCM) in Doberman Pinschers (DP), but myocardial damage might be detected earlier using a high-sensitivity cardiac troponin I (hs-cTnI) assay.

Objective: To evaluate and compare an hs-cTnI assay (Advia Centaur TnI-Ultra assay) with a conventional cTnI assay in DP with different stages of DCM and in healthy DP.

Animals: Three hundred forty-five examinations from 162 DP with and 179 DP without DCM. Read More

Heart Rhythm 2018 Nov 30. Epub 2018 Nov 30.

Texas Cardiac Arrhythmia Institute at St. David's Medical Center, Austin, Texas. Electronic address:

Background: The optimal site of ablation of idiopathic left ventricular outflow tract (LVOT) ventricular arrhythmias (VAs) is challenging as activation mapping can reveal similar activation times, suggesting an intramural origin.

Objective: We sought to assess whether in patients with intramural VAs and with multiple early activation sites (EASs), sequential ablation of all the early ASs could improve acute and long-term outcomes.

Methods: A total of 116 patients undergoing ablation for symptomatic LVOT VAs were enrolled in this study. Read More

J Cardiovasc Electrophysiol 2019 Feb 27;30(2):205-211. Epub 2018 Dec 27.

Cardiology Department, University of Tours, Tours, France.

Introduction: Ablation of premature ventricular contractions (PVCs) has emerged as a safe and effective treatment in patients experiencing a high PVCs burden. Mapping of PVCs origin may sometimes be challenging. We sought to evaluate the accuracy of a new electrophysiological criterion, the distal-to-proximal (DP) delay, at localizing the optimal site for ablation of ventricular ectopic foci. Read More

PLoS Comput Biol 2018 11 30;14(11):e1006594. Epub 2018 Nov 30.

Biological Physics Group, School of Physics & Astronomy, The University of Manchester, Manchester, United Kingdom.

Cardiac electrical alternans (CEA), manifested as T-wave alternans in ECG, is a clinical biomarker for predicting cardiac arrhythmias and sudden death. However, the mechanism underlying the spontaneous transition from CEA to arrhythmias remains incompletely elucidated. In this study, multiscale rabbit ventricular models were used to study the transition and a potential role of INa in perpetuating such a transition. Read More

J Am Heart Assoc 2018 Dec;7(23):e010584

1 Department of Cardiology Austin Health University of Melbourne Melbourne Australia.

Background The relationship between mitral valve prolapse ( MVP ) and sudden cardiac death ( SCD ) remains controversial. In this systematic review, we evaluate the relationship between isolated MVP and SCD to better define a potential high-risk subtype. In addition, we determine whether premortem parameters could predict SCD in patients with MVP and the incidence of SCD in MVP . Read More

Int Heart J 2019 Jan 20;60(1):78-85. Epub 2018 Nov 20.

Department of Cardiology, Kyorin University Hospital.

A novel, sensor-based, electromagnetic, non-fluoroscopic catheter visualization (NFCV) system shows tracked catheters directly on pre-acquired fluoroscopy or cine loops. We aimed to evaluate the effectiveness of this system in the setting of catheter ablation for idiopathic premature ventricular contractions/ventricular tachycardia (i-PVC/VT).A total of 30 i-PVC/VT ablation procedures were performed using the NFCV system in conjunction with three-dimensional electroanatomic mapping system (3D-EMS) between January 2013 and April 2017. Read More

Int Heart J 2019 Jan 20;60(1):199-203. Epub 2018 Nov 20.

Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences.

A 60-year-old female with premature ventricular contractions (PVCs) originating from the bottom of the posteromedial papillary muscle of the left ventricle underwent radiofrequency catheter ablation (RFCA) using an irrigated-tip catheter. During ablation of the PVCs, a loud steam pop was observed. Intracardiac echocardiography (ICE) revealed a growing, hyperechogenic intramyocardial microbubble formation around the catheter tip. Read More

J Cardiovasc Electrophysiol 2018 Nov 21. Epub 2018 Nov 21.

Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.

Eur Heart J 2018 Nov 17. Epub 2018 Nov 17.

Department of Cardiology, Karolinska University Hospital, Solna, Sweden.

Aims: Catheter ablation is considered the treatment of choice for many tachyarrhythmias, but convincing 'real-world' data on efficacy and safety are lacking. Using Swedish national registry data, the ablation spectrum, procedural characteristics, as well as ablation efficacy and reported adverse events are reported.

Methods And Results: Consecutive patients (≥18 years of age) undergoing catheter ablation in Sweden between 01 January 2006 and 31 December 2015 were included in the study. Read More

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:5018-5021

The fluctuation of an RR interval (RRI) on an electrocardiogram (ECG) is called heart rate variability (HRV). HRV reflects the autonomic nerve activity, thus HRV analysis has been used for health monitoring such as stress estimation, drowsiness detection, epileptic seizure prediction, and cardiovascular disease diagnosis. However, RRI and HRV features are easily affected by arrhythmia, which deteriorates the health monitoring performance. Read More

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:2551-2554

Premature ventricular contraction (PVC) is usually considered to as benign arrhythmia in the absence of structural heart diseases. However, frequent premature beats may significantly increase the risk of heart failure and even death by an arrhythmia-induced cardiomyopathy. Therefore, high PVC counts have been considered as an approach to predict the risk of severe arrhythmias. Read More

Tunis Med 2018 Apr;96(4):155-159

Introduction: Premature ventricular complexes (PVC) are generally considered as a benign electrocardiographic abnormality in the athleticpopulation. However it may be indicative of underlying heart disease which may increase the risk of sudden death. This implies the need forcardiological evaluation before indicating the ability to practice competitive sports. Read More

IEEE Trans Med Imaging 2018 Nov 9. Epub 2018 Nov 9.

Building a data-driven model to localize the origin of ventricular activation from 12-lead electrocardiograms (ECG) requires addressing the challenge of large anatomical and physiological variations across individuals. The alternative of a patientspecific model is, however, difficult to implement in clinical practice because training data must be obtained through invasive procedures. Here, we present a novel approach that overcomes this problem of the scarcity of clinical data by transferring the knowledge from a large set of patient-specific simulation data while utilizing domain adaptation to address the discrepancy between simulation and clinical data. Read More

Heart Rhythm 2018 Nov 7. Epub 2018 Nov 7.

Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, Kentucky. Electronic address:

Background: Type 2 diabetes (T2D) increases arrhythmia risk through incompletely elucidated mechanisms. Ventricular arrhythmias could be initiated by delayed afterdepolarizations (DADs) resulting from elevated spontaneous sarcoplasmic reticulum (SR) Ca release (SR Ca leak).

Objective: The purpose of this study was to test the role of DADs and SR Ca leak in triggering arrhythmias in T2D hearts. Read More

PLoS One 2018 6;13(11):e0207100. Epub 2018 Nov 6.

Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.

Aims: Catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1) predisposes to ventricular tachyarrhythmias (VTs) during high heart rates due to physical or psychological stress. The essential role of catecholaminergic effects on ventricular cardiomyocytes in this situation is well documented, but the importance of heart rate per se for arrhythmia initiation in CPVT1 is largely unexplored.

Methods And Results: Sixteen CPVT1 patients performed a bicycle stress-test. Read More

Int Heart J 2018 Nov 5;59(6):1246-1252. Epub 2018 Nov 5.

Department of Cardiology, First Affiliated Hospital of Dalian Medical University.

In this study, we aim to investigate the association of serum uric acid (SUA) with the prevalence of premature ventricular contraction (PVC). The relationship between SUA and the prevalence of PVC in 98,965 subjects (79,034 male subjects, mean age: 51.9 ± 12. Read More

J Am Heart Assoc 2018 Sep;7(17):e007898

1 School of Mathematical Sciences Rochester Institute of Technology Rochester NY.

Background Ventricular tachyarrhythmias are often preceded by short sequences of premature ventricular complexes. In a previous study, a restitution-based computational model predicted which sequences of stimulated premature complexes were most likely to induce ventricular fibrillation in canines in vivo. However, the underlying mechanism, based on discordant-alternans dynamics, could not be verified in that study. Read More

Korean J Pediatr 2018 Nov 24;61(11):362-365. Epub 2018 Oct 24.

Division of Pediatric Cardiology, Department of Pediatrics, Kyungpook National University Children's Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.

Purpose: This study aimed to analyze changes in QRS duration and cardiothoracic ratio (CTR) following pulmonary valve replacement (PVR) in patients with tetralogy of Fallot (TOF).

Methods: Children and adolescents who had previously undergone total repair for TOF (n=67; median age, 16 years) who required elective PVR for pulmonary regurgitation and/or right ventricular out tract obstruction were included in this study. The QRS duration and CTR were measured pre- and postoperatively and postoperative changes were evaluated. Read More

Heart Rhythm 2018 Oct 16. Epub 2018 Oct 16.

Department of Cardiology, Wuhan Asian Heart Hospital, Wuhan, China.

Background: Idiopathic premature ventricular complexes (PVCs) that originate from the left fascicular system have rarely been reported.

Objective: The present study aimed to investigate the electrophysiological characteristics and the ablation strategy for this category of PVCs.

Methods: Of 648 patients with idiopathic PVCs, 27 were enrolled in this study. Read More

JACC Clin Electrophysiol 2018 Oct 27;4(10):1300-1307. Epub 2018 Jun 27.

Arrhythmia Center, Department of Cardiology, University of California, Los Angeles, Los Angeles, California.

Objectives: The purpose of this study was to determine the ventricular arrhythmia (VA) substrates in patients with unoperated and post-surgical Ebstein's Anomaly (EA).

Background: EA is associated with variable atrialization of the right ventricle and a propensity for VA and sudden death. There are scant data on catheter ablation for VA in this population. Read More

J Arrhythm 2018 Oct 22;34(5):572-575. Epub 2018 Jun 22.

Division of Cardiovascular Medicine Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan.

A 69-year-old man, who had undergone surgery for mitral and tricuspid regurgitation with the Maze procedure for paroxysmal atrial fibrillation, was admitted with an episode of syncope due to sick sinus syndrome. Three days after implantation of a dual-chamber pacemaker (Accent MRI™, St. Jude Medical Inc. Read More

Heart Lung Circ 2019 Jan 4;28(1):178-190. Epub 2018 Oct 4.

Department of Cardiology, The Prince Charles Hospital, Brisbane, Qld, Australia; Faculty of Medicine, University of Queensland, Brisbane, Qld, Australia. Electronic address:

Frequent ventricular ectopy is a common clinical presentation in patients suffering idiopathic ventricular outflow tract arrhythmias. These are focal arrhythmias that generally occur in patients without structural heart disease and share a predilection for characteristic anatomic sites of origin. Mechanistically, they are generally due to cyclic adenosine monophosphate (cAMP)-mediated triggered activity. Read More

Pacing Clin Electrophysiol 2018 12 31;41(12):1619-1626. Epub 2018 Oct 31.

Department of Cardiac Rhythm Management, Medtronic, Mounds View, Minnesota.

Background: Despite available evidence that implantable cardioverter defibrillators (ICDs) reduce all-cause mortality among patients at risk for sudden cardiac death, utilization of ICDs is low especially in developing countries.

Objective: To summarize reasons for ICD or cardiac resynchronization therapy defibrillator implant refusal by patients at risk for sudden cardiac arrest (Improve SCA) in developing countries.

Methods: Primary prevention (PP) and secondary prevention (SP) patients from countries where ICD use is low were enrolled. Read More

Heart Lung Circ 2019 Jan 29;28(1):110-122. Epub 2018 Sep 29.

Department of Cardiology, Royal Melbourne Hospital, Faculty of Medicine, Dentistry and Health Science, University of Melbourne, Melbourne, Vic, Australia.

Ventricular fibrillation (VF) is a common and life-threatening arrhythmia resulting in sudden cardiac death (SCD). Due to the inherent challenges of mapping VF in humans, the underlying mechanisms that initiate and sustain this common arrhythmia are still poorly understood. In high-risk patients and survivors of SCD, implantable cardioverter defibrillators (ICD) play a central role in treating VF episodes, however, ICDs do not prevent VF recurrences and patients remain at risk of electrical storm and multiple shocks that are often refractory to escalation of medical therapy. Read More

J Cardiol Cases 2018 Oct 23;18(4):128-131. Epub 2018 Jun 23.

Department of Cardiology, JCHO Hoshigaoka Medical Center, Hirakata, Japan.

A 76-year-old man presented with frequent premature ventricular contractions (PVCs). The electrophysiological findings revealed the origin of the PVCs was in the posterior-superior process of the left ventricle (PSP-LV), which is anatomically adjacent to the infero-medial aspect of the right atrium (RA). After a failed ablation from the LV, ablation in the RA eliminated the PVCs. Read More