Int J Gynecol Pathol 2019 Jul;38(4):326-334
Department of Obstetrics and Gynecology, Kudret International Hospital (M.K.) Department of Obstetrics and Gynecology, Ankara Education and Research Hospital (Z. Kurdoglu), Ankara Department of Obstetrics and Gynecology, Medicana Konya (Z. Kucukaydin) Department of Pathology, Konya Training and Research Hospital (Y.U.), Konya Department of Pathology, Yuzuncu Yil University School of Medicine, Van (G.B., S.O.), Turkey.
Laminin receptor 1 may have a role in the progression from endometrial hyperplasia with or without atypia to endometrial cancer. Therefore, we aimed to investigate the pattern, percentage, and intensity of laminin receptor 1 expression in normal, hyperplastic, and neoplastic endometrium. Paraffin blocks of 131 specimens with the diagnoses of normal endometrium (n=25), endometrial hyperplasia with atypia (n=21) or without atypia (n=55), and endometrial cancer (n=30) were immunostained with laminin receptor 1 antibody, and its expression percentage, pattern, and intensity in the epithelial cytoplasm, basement membrane, and endometrial stroma of these tissues were assessed. Read More