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Medicina (Kaunas) 2022 Apr 29;58(5). Epub 2022 Apr 29.

Department of Obstetrics and Gynecology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

: Minimally invasive procedures, such as double-J ureteric stenting, could be a promising therapeutic alternative to conservative management of obstructive urinary tract pathology. We aimed to evaluate the safety and effectiveness of double-J ureteric stenting in pregnant women with ureterohydronephrosis or urolithiasis, along with their infectious complications, and to assess the pregnancy outcomes of this cohort of patients in comparison with a control group. : This observational retrospective study included 52 pregnant patients who underwent double-J ureteric stenting for urologic disorders in the Urology Department of 'C. Read More

Actas Urol Esp (Engl Ed) 2022 Jun 9;46(5):259-267. Epub 2022 May 9.

Department of Urology, Louisiana State University Health Sciences Center, Shreveport, USA. Electronic address:

Objective: Given the challenges involved in diagnosis and treatment of pregnant women with urolithiasis, we aim to review the imaging modalities and current endourological management of these patients.

Materials And Methods: We performed a review of the available literature on urolithiasis in pregnancy. This included evaluation, diagnostic imaging, and therapeutic options. Read More

Int J Hematol 2022 May 9. Epub 2022 May 9.

Department of Laboratory Medicine, Tokyo Medical University, Tokyo, Japan.

Type 3 von Willebrand disease (VWD), a rare and severe subtype, can produce inhibitors in roughly 5% to 10% of cases. We present a case of type 3 VWD with inhibitors in late pregnancy, which was successfully managed with a combination of neutralization and factor (F)VIII replacement during cesarean delivery. The patient, a 30-year-old woman, had no history of inhibitors despite over 100 exposures to VWF/FVIII. Read More

BMJ Open 2022 05 2;12(5):e056510. Epub 2022 May 2.

Department of Clinical Laboratory, Ruian People's Hospital, Ruian, China.

Introduction: Urolithiasis affects many people throughout their lives. Among the maternal population, although the morbidity of acute urolithiasis in pregnant women is unremarkable, it is the leading cause of hospitalisation during pregnancy. There is no effective clinical diagnostic tool to help doctors diagnose diseases. Read More

J Ayub Med Coll Abbottabad 2022 Jan-Mar;34(1):67-72

Section of Urology, Department of Surgery, The Aga Khan University Hospital, Karachi, Pakistan.

Background: Ureteroscopy (URS) is a safe and highly effective treatment option for treatment of ureteral calculi. With the advancement of technology, there is also expansion of its indications including use in early or emergency setting. This study aims to compare safety and efficacy of emergency ureteroscopy (EmURS) versus elective ureteroscopy (ElURS) for ureteral stones. Read More

Can Urol Assoc J 2022 Apr 11. Epub 2022 Apr 11.

Department of Urology, Louisiana State University Health Shreveport, Shreveport, LA, United States.

Introduction: Retained ureteral stents may constitute a technical challenge. The purpose of this study was to analyze the patient population with retained ureteral stents with regards to stent sizes to better understand if these factors could play a pivotal role in their encrustation.

Methods: After institutional review board approval, we retrospectively analyzed the data of patients who underwent multimodal surgical procedures for the removal of retained ureteral stents from 2010-2018. Read More

J Endourol 2022 Mar 29. Epub 2022 Mar 29.

Royal College of Surgeons in Ireland, 8863, Dublin, Ireland.

Introduction Approximately 3% of pregnancies are complicated by symptomatic hydronephrosis and up to 0.8% with urolithiasis. Pain, coupled with the possibility of superimposed infection, increases the risks of premature labour and delivery, fetal loss and caesarian sections. Read More

BMC Urol 2022 Mar 7;22(1):30. Epub 2022 Mar 7.

Department of Obstetrics and Gynecology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.

Background: Renal colic is a surgical emergency in pregnancy that is caused by a range of non-obstetric factors and known to occur more frequently during the second and third trimesters. Several studies have reported that up to 70-80% of stones pass spontaneously during pregnancy. There are some patients will not pass their stones and will ultimately require surgical intervention. Read More

Front Public Health 2022 14;10:843383. Epub 2022 Feb 14.

Department of Obstetrics and Gynecology, The First People's Hospital of Kunshan Affiliated With Jiangsu University, Suzhou, China.

Objective: The association between history of gestational diabetes mellitus (GDM) and risk of kidney stones has not been reported. GDM increases the risk of long-term complications including diabetes, hypertension and metabolic syndrome, which are risk factors of kidney stones. This study aimed to explore the association between previous GDM and odds of kidney stones. Read More

Cent European J Urol 2021 6;74(4):571-578. Epub 2021 Dec 6.

Department of Urology, University Hospital Southampton, Southampton, United Kingdom.

Encrustation of ureteral stents can represent a complex challenge. Patients can require multiple intervention types as well as several operative sessions. Our aim was to establish a practical guide for managing such cases as well as an accompanying treatment algorithm. Read More

Int J Clin Pharmacol Ther 2022 Apr;60(4):167-175

Aim: The aim of this study was to analyze the association between widely used contraceptive methods and the manifestation of lower urinary tract infections (LUTI) in patients treated in gynecological practices in Germany.

Materials And Methods: This study was based on IQVIA Disease Analyzer database and includes a total of 133,638 females aged between 16 and 50 years who received an initial diagnosis of LUTI including cystitis (ICD-10: N39.0, N30. Read More

World J Urol 2022 Mar 7;40(3):857-864. Epub 2021 Dec 7.

Department of Urology, University Hospital Southampton, Southampton, UK.

Introduction: Working in surgery while pregnant is challenging. Navigating this period safely is of paramount importance. Anecdotal observation suggests that there exists great variation among European nations in regard to maternity leave and radiation safety. Read More

BMC Urol 2021 Nov 29;21(1):164. Epub 2021 Nov 29.

University of Minnesota, 420 Delaware St. S. E., MMC 394, Minneapolis, MN, 55455, USA.

Background: Nephrocalcinosis is often asymptomatic but can manifest with renal colic or hematuria. There is no reported association between nephrocalcinosis and renal vascular malformations, which may also be a source of hematuria. We herein present a case of a patient with hematuria related to nephrocalcinosis and renal papillary varicosities. Read More

Prog Urol 2021 Nov;31(15):956-966

Centre Hospitalier universitaire de Grenoble, 38043 Grenoble cedex 9, France; TIMC-IMAG, CNRS 5525, La Tronche Cedex 9, France.

Introduction: The aims of this narrative review was to report on the contemporary data of renal colic (RC) in terms of epidemiology and pressure on emergency structures and also to describe the latest therapeutic developments about uncomplicated RC, depending on the pediatric, adult and pregnancy population.

Material And Methods: A request to the health surveillance network for emergencies and deaths (SurSaUD®, Santé Publique France) revealed original data on the contemporary epidemiology of renal colic. A narrative synthesis of the articles (French, English) available on the Pubmed database was produced in June 2021. Read More

Comput Math Methods Med 2021 29;2021:9548312. Epub 2021 Oct 29.

Department of Ultrasound, The First People's Hospital of Fuyang (Fuyang First Affiliated Hospital of Zhejiang Chinese Medical University Ben Giang College), Hangzhou, China 311400.

Objective: To explore the image enhancement model based on deep learning on the effect of ureteroscopy with double J tube placement and drainage on ureteral stones during pregnancy. We compare the clinical effect of ureteroscopy with double J tube placement on pregnancy complicated with ureteral stones and use medical imaging to diagnose the patient's condition and design a treatment plan.

Methods: The image enhancement model is constructed using deep learning and implemented for quality improvement in terms of image clarity. Read More

J Lasers Med Sci 2021 19;12:e50. Epub 2021 Sep 19.

Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Currently, lasers are used to treat many diseases and their complications. However, the use of lasers in pregnant patients is still controversial. In this review, the application of lasers in the fields of urology, surgery, obstetrics, dermatology, and musculoskeletal disorders is evaluated. Read More

Hinyokika Kiyo 2021 Jul;67(7):323-326

The Department of Urology, Yamagata Prefectural Central Hospital.

A 238-day-old female infant (122 days of age corrected for prematurity, weight 4,847 g) presented with macrohematuria. She was born at 23 weeks and3 days of pregnancy. Her birth weight was 492 g. Read More

Chin Med J (Engl) 2021 07 29;134(16):1994-1996. Epub 2021 Jul 29.

Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.

J Vasc Interv Radiol 2021 Aug;32(8):1231-1233

Department of Imaging Sciences, University of Rochester Medical Center, Rochester, New York.

This study evaluated outcomes for percutaneous nephrostomy tube placement in pregnant patients, including potential complications that required early, unplanned tube exchange. A retrospective review was conducted for 51 pregnant patients and a nonpregnant cohort matched 1:1 who received percutaneous nephrostomy tube placement between 2012 and 2020. Factors potentially contributing to unplanned tube exchanges were analyzed, including gestational age, prevalence and severity of hydronephrosis, presence of renal calculi, and serum calcium level. Read More

J Endourol 2022 01 29;36(1):138-142. Epub 2021 Oct 29.

Department of Urology, Stanford University School of Medicine, Stanford, California, USA.

To determine the risk of postpartum urinary stone disease in women with a history of stone disease during pregnancy. Using the Optum de-identified Clinformatics Datamart we identified pregnant women with urinary stone disease in the United States between January 2003 to December 2017 by standardized International Classification of Diseases Ninth and Tenth Editions (ICD-9 and ICD-10), and Current Procedural Terminology code criteria. We limited the cohort to include women without evidence of urinary stone disease before pregnancy. Read More

J Nephrol 2021 10 26;34(5):1569-1580. Epub 2021 Jun 26.

Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Qingchun Road 79, Hangzhou, 31000, People's Republic of China.

Background: The effect of urolithiasis on pregnancy-related outcomes remains unknown. The aim of this study was to determine the risk of adverse maternal and neonatal outcomes.

Methods: We searched PubMed, Embase, and the Cochrane Library through December 2020 for studies reporting on adverse maternal and neonatal outcomes in patients with urolithiasis. Read More

BMJ Case Rep 2021 May 31;14(5). Epub 2021 May 31.

Urology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Urolithiasis is the most common non-obstetric complication in pregnancy and has the potential to cause grave consequences resulting in pregnancy loss. We present two such cases. First, a 24-year-old woman, 5 weeks pregnant with a history of urolithiasis presented with right flank pain and fever. Read More

J Gynecol Obstet Hum Reprod 2021 Nov 10;50(9):102161. Epub 2021 May 10.

Department of Obstetrics and Gynecology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada; Center for Clinical Epidemiology and Community Studies, Jewish General Hospital, Montreal, Quebec, Canada. Electronic address:

Objectives: Although urolithiasis is relatively common in the general population, there is limited information on this condition available in the pregnant population. The objectives of this study are to identify the incidence of urolithiasis in pregnancy, as well as to compare maternal and fetal outcomes associated with urolithiasis in pregnancy.

Methods: Using the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample database from the United States, a population-based retrospective cohort study consisting of pregnant women who delivered between 1999 and 2015 was conducted. Read More

J Matern Fetal Neonatal Med 2021 May 9:1-6. Epub 2021 May 9.

Department of Obstetrics and Gynecology, Jewish General Hospital, McGill University, Montreal, Canada.

Purpose: To evaluate the effect of pregnancy on the clinical presentation, inpatient procedure rates, and length of hospital stay, on women with urolithiasis.

Materials And Methods: We carried out a matched cohort study using the United States' Healthcare Cost and Utilization Project-Nationwide Inpatient Sample database from 1999 to 2015. Pregnant women with urolithiasis were compared to age-matched non-pregnant women (1:1) with urolithiasis. Read More

Elife 2021 04 27;10. Epub 2021 Apr 27.

Department of Medicine Solna, Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden.

Background: There are multiple known associations between the ABO and RhD blood groups and disease. No systematic population-based studies elucidating associations between a large number of disease categories and blood group have been conducted.

Methods: Using SCANDAT3-S, a comprehensive nationwide blood donation-transfusion database, we modeled outcomes for 1217 disease categories including 70 million person-years of follow-up, accruing from 5. Read More

Am J Kidney Dis 2021 09 15;78(3):409-417. Epub 2021 Apr 15.

Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN. Electronic address:

Rationale & Objective: There are several well-known anatomical and physiological changes during pregnancy that could contribute to kidney stone formation, but evidence that they increase the risk of kidney stones during pregnancy is lacking. We determined whether there was an increased risk of a first-time symptomatic kidney stone during and after pregnancy.

Study Design: A population-based matched case-control study. Read More

Cureus 2021 Mar 7;13(3):e13752. Epub 2021 Mar 7.

Department of Urology, Harran University, Şanlıurfa, TUR.

Introduction: Urolithiasis during pregnancy is an important health concern that can affect maternal and foetal health. If left untreated, it can cause obstetric complications, such as spontaneous abortion and preterm delivery. In this study, we aimed to evaluate urolithiasis and its treatment in pregnant women. Read More

J Endourol 2021 Oct 26;35(10):1460-1466. Epub 2021 Mar 26.

Department of Urology, Al-Azhar University, Cairo, Egypt.

To evaluate the safety and efficacy of ultrasound (US) and primary ureteroscopy (URS) in the management of symptomatic obstructive ureteric stones during pregnancy. A prospective multicenter study was performed between June 2013 and December 2019, including all consecutive pregnant patients admitted to three urology centers with intractable renal colic with obstructed ureter secondary to obstructive ureteral calculi. Color Doppler ultrasound was used to evaluate renal Resistive Index (RI) and ureter jet. Read More

Arch Ital Urol Androl 2021 Mar 18;93(1):35-41. Epub 2021 Mar 18.

Department of Obstetrics and Gynecology, School of Medicine, Istanbul Medipol University, Istanbul.

Purpose: The aim of this study is to determine the proportion of maternal hydronephrosis and symptomatic cases requiring treatment in pregnant women without ureteral stones and the characteristics of these cases.

Materials And Methods: Between February 2018 and April 2019, all pregnant women followed for pregnancy in obstetrics and outpatient policlinic were evaluated prospectively. Maternal hydronephrosis rate, degree of hydronephrosis and side, symptomatic hydronephrosis rate, maximum renal anteroposterior diameter of renal pelvis and visual analogue scale were detected. Read More

Arch Esp Urol 2021 Jan;74(1):80-93

Servicio de Urología. Hospital General Universitario de Alicante. Alicante. España. Alicante Institute for Health and Biomedical Research (ISABIAL). Alicante. España.

Introduction: Medical Expulsive Treatment (MET) for ureteral stones has been questioned for the last few years.

Objectives: The main goal of our study is to define the indications of MET, the different drugs that are used and their effectiveness and to propose a follow-up strategy. Secondary objectives include the effectiveness of MET in some special subgroups such as pregnant women and children and to assess aspects of MET cost-effectiveness compared with other options for ureteral lithiasis treatment (ureterorenoscopy or extracorporeal shock wave lithotripsy). Read More