3,627 results match your criteria Pregnancy Urinary Tract Infections


Operative vaginal delivery and post-partum infection.

Best Pract Res Clin Obstet Gynaecol 2019 Apr 29;56:93-106. Epub 2018 Sep 29.

National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, UK. Electronic address:

During the past decade, there has been an increase in the awareness of infections associated with pregnancy and delivery. The most significant cause of post-partum infection is caesarean section; 20-25% of operations are followed by wound infections, endometritis or urinary tract infections. Approximately 13% of women in the UK undergo operative vaginal delivery (OVD) with forceps or vacuum, which is also associated with an increased risk of infection, estimated at 0. Read More

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http://dx.doi.org/10.1016/j.bpobgyn.2018.09.005DOI Listing
April 2019
1 Read

[In-hospital management of acute complicated urinary tract infections].

Nephrol Ther 2019 Apr;15 Suppl 1:S27-S32

Unité de bactériologie, groupe hospitalier Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France; Université Paris-Est-Créteil-Val-de-Marne, avenue du Général-de-Gaulle, 94010 Créteil cedex, France.

Upper tract urinary tract infections that require hospitalization have been the focus of national recommendations in 2018 by the French society of infectious diseases (Spilf). We here propose to discuss several complex-challenging situations: severe infection with sepsis, pyelonephritis in the pregnant woman, management of infections involving multiresistant bacteria and infection in polycystic kidney disease. Read More

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http://dx.doi.org/10.1016/j.nephro.2019.02.002DOI Listing
April 2019
1 Read

Hospital-Based Study of Maternal, Perinatal and Neonatal Outcomes in Adolescent Pregnancy Compared to Adult Women Pregnancy.

Open Access Maced J Med Sci 2019 Mar 14;7(5):760-766. Epub 2019 Mar 14.

Faculty of Medical Sciences, University of Tetovo, Tetovo, Republic of Macedonia.

Background: Adolescent pregnancy, defined as a pregnancy in girls aged 10 to 19 years. Adolescent mothers are at high risk for maternal and neonatal complications.

Aim: To compare maternal, perinatal and neonatal outcomes in adolescents and adult women aged 20-24 years. Read More

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http://dx.doi.org/10.3889/oamjms.2019.210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447330PMC
March 2019
3 Reads

Therapeutic Problems and Pregnancy in a Patient With Infantile Nephropathic Cystinosis: A Case Report.

Transplant Proc 2019 Mar 3;51(2):545-547. Epub 2019 Jan 3.

Department of Transplantation Medicine, Nephrology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.

Background: Cystinosis is a rare genetic disorder characterized by the abnormal accumulation of cystine in the lysosomes of various tissues and organs leading to their dysfunction. The most common type is the infantile nephropathic cystinosis which without treatment leads to renal failure and before the introduction of cysteamine was the cause of death before puberty.

Case Presentation: A 27-year-old female patient with infantile cystinosis developed end-stage renal disease at the age of 10. Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.12.026DOI Listing
March 2019
2 Reads

Long-term Risk of Neuropsychiatric Disease After Exposure to Infection In Utero.

JAMA Psychiatry 2019 Mar 6. Epub 2019 Mar 6.

Centre for Perinatal Medicine & Health, Department of Obstetrics & Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Importance: The developmental origins of mental illness are incompletely understood. Although the development of autism and schizophrenia are linked to infections during fetal life, it is unknown whether more common psychiatric conditions such as depression might begin in utero.

Objective: To estimate the risk of psychopathologic conditions imparted from fetal exposure to any maternal infection while hospitalized during pregnancy. Read More

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http://dx.doi.org/10.1001/jamapsychiatry.2019.0029DOI Listing
March 2019
5 Reads

Management of myasthenia gravis during pregnancy.

Indian J Pharmacol 2018 Nov-Dec;50(6):302-308

Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

The management of myasthenia gravis (MG) during pregnancy requires special skills as both diseases as well as its treatment can have deleterious effects on mother and fetus. MG often affects women in second and third decades of life during the childbearing age. Exacerbations of MG are likely to occur during the first trimester and postpartum period. Read More

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http://www.ijp-online.com/text.asp?2018/50/6/302/250590
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http://dx.doi.org/10.4103/ijp.IJP_452_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364336PMC
February 2019
7 Reads

Human β-defensin 1 in follicular fluid and semen: impact on fertility.

J Assist Reprod Genet 2019 Feb 2. Epub 2019 Feb 2.

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

Purpose: β-defensins are antimicrobial peptides expressed at mucosal level of male and female genito-urinary tract, where they exert protective functions against infections, possibly preserving human health and fertility. In our study, we investigated the possible involvement of β-defensins in female and male infertility in Italian infertile couples (i) evaluating the presence of human β-defensin 1 (hBD-1) in follicular fluid (FF) and its correlation with in vitro fertilization (IVF) outcomes; (ii) investigating the relationship between hBD-1 levels in semen and IVF outcomes (comprising correlation with sperm parameters); and (iii) exploring the effect of hBD-1 peptide on spermatozoa motility in vitro.

Methods: A perspective observational analytic pilot study was conducted. Read More

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http://dx.doi.org/10.1007/s10815-019-01409-wDOI Listing
February 2019
3 Reads

Maternal levels of perfluoroalkyl substances (PFASs) during pregnancy and childhood allergy and asthma related outcomes and infections in the Norwegian Mother and Child (MoBa) cohort.

Environ Int 2019 Mar 23;124:462-472. Epub 2019 Jan 23.

Norwegian Institute of Public Health, Division of Infection Control and Environmental Health, Oslo, Norway. Electronic address:

Introduction: Prenatal exposure to perfluoroalkyl substances (PFASs) has been inconsistently associated with asthma and allergic diseases and increased number of infections in early childhood. We examined the association of PFASs measured in pregnancy with childhood asthma, allergies and common infectious diseases in a prospective pregnancy cohort followed to age 7 years.

Material And Methods: Six PFASs (out of 19 measured) with at least 80% of measurements above the limit of quantification (LOQ) in maternal plasma during pregnancy in two subcohorts of the Norwegian Mother and Child Cohort Study (MoBa) were analyzed in relation to health outcomes: perfluorooctane sulfonic acid (PFOS), acid (PFOA), perfluorohexane sulfonic acid (PFHxS), perfluorononanoic acid (PFNA), perfluoroundecanoic acid (PFUnDA), and perfluoroheptane sulfonic acid (PFHpS). Read More

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http://dx.doi.org/10.1016/j.envint.2018.12.041DOI Listing
March 2019
8 Reads

Plazomicin (Zemdri) - a new aminoglycoside antibiotic.

Authors:

Med Lett Drugs Ther 2018 Nov;60(1559):180-182

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November 2018
2 Reads

Maternal nutritional status and related pregnancy outcomes following bariatric surgery: A systematic review.

Surg Obes Relat Dis 2018 Nov 23. Epub 2018 Nov 23.

Department of Nutrition, Hadassah-Hebrew University Medical Center, Ein-Kerem Campus, Jerusalem, Israel.

Up to 80% of patients who undergo bariatric surgery are women of childbearing age. Coupled with improved fertility in women with obesity after bariatric surgery, pregnancy postbariatric surgery has become increasingly more common. Although numerous studies have evaluated associations of bariatric surgery with pregnancy outcomes, the effect of maternal nutritional status on maternal and perinatal outcomes is not well established. Read More

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http://dx.doi.org/10.1016/j.soard.2018.11.018DOI Listing
November 2018
5 Reads
4.066 Impact Factor

Marked reduction in fertility among African women with urogenital infections: A prospective cohort study.

PLoS One 2019 10;14(1):e0210421. Epub 2019 Jan 10.

Centre for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

Background: There is paucity of data on risk factors for reduced fertility in low-income countries.

Objective: To investigate factors associated with fertility among women in rural north eastern Tanzania.

Subjects And Methods: A cohort of 1248 non-pregnant women was followed with urine pregnancy testing every third month or more regularly if they reported a missed menstrual period. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210421PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328149PMC
January 2019
7 Reads

A High Adherence to Six Food Targets of the Mediterranean Diet in the Late First Trimester is Associated with a Reduction in the Risk of Materno-Foetal Outcomes: The St. Carlos Gestational Diabetes Mellitus Prevention Study.

Nutrients 2018 Dec 31;11(1). Epub 2018 Dec 31.

Endocrinology and Nutrition Department, Hospital Clínico San Carlos and Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.

A prenatal diet affects materno-foetal outcomes. This is a post hoc analysis of the St. Carlos gestational diabetes mellitus (GDM) Prevention Study. Read More

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http://dx.doi.org/10.3390/nu11010066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356317PMC
December 2018
7 Reads

Points & Pearls: First trimester pregnancy emergencies: recognition and management

Emerg Med Pract 2019 Jan 1;21(Suppl 1):1-2. Epub 2019 Jan 1.

Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY

Timely management of patients presenting to the ED while in their first trimester of pregnancy can improve outcomes for both the patient and the fetus. Common obstetric problems encountered include vaginal bleeding and miscarriage, ectopic pregnancy and pregnancy of undetermined location, and nausea and vomiting of pregnancy, including hyperemesis gravidarum. Optimal diagnostic approaches and management strategies are covered, including which antiemetics are safe to give in pregnancy. Read More

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January 2019
7 Reads

A machine learning approach to investigate potential risk factors for gastroschisis in California.

Birth Defects Res 2019 Mar 26;111(4):212-221. Epub 2018 Dec 26.

Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California.

Background: To generate new leads about risk factors for gastroschisis, a birth defect that has been increasing in prevalence over time, we performed an untargeted data mining statistical approach.

Methods: Using data exclusively from the California Center of the National Birth Defects Prevention Study, we compared 286 cases of gastroschisis and 1,263 non-malformed, live-born controls. All infants had delivery dates between October 1997 and December 2011 and were stratified by maternal age at birth (<20 and ≥ 20 years). Read More

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http://doi.wiley.com/10.1002/bdr2.1441
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http://dx.doi.org/10.1002/bdr2.1441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397054PMC
March 2019
10 Reads

Risk factors for congenital microcephaly in the pre-Zika era.

Birth Defects Res 2019 Jan 24;111(2):96-118. Epub 2018 Dec 24.

Slone Epidemiology Center at Boston University, Boston, Massachusetts.

Background: The Zika epidemic has brought increased attention to congenital microcephaly as a birth outcome. However, little is known about risks for microcephaly unrelated to Zika.

Methods: Using data from the Slone Epidemiology Center Birth Defects Study from 1993 to 2015, we identified 57 cases of microcephaly alone ("isolated") and 109 cases of microcephaly that included other major birth defects ("non-isolated"), and considered a large number of potential risk factors including demographic characteristics, illnesses, and medications used during pregnancy. Read More

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http://dx.doi.org/10.1002/bdr2.1443DOI Listing
January 2019
3 Reads

First trimester pregnancy emergencies: recognition and management.

Authors:
Ryan Pedigo

Emerg Med Pract 2019 Jan 1;21(1):1-20. Epub 2019 Jan 1.

Director of Undergraduate Medical Education, Harbor-UCLA Medical Center, Torrance, CA; Assistant Professor of Emergency Medicine, David Geffen School of Medicine, Los Angeles, CA.

Timely management of patients presenting to the ED while in their first trimester of pregnancy can improve outcomes for both the patient and the fetus. Common obstetric problems encountered include vaginal bleeding and miscarriage, ectopic pregnancy and pregnancy of undetermined location, and nausea and vomiting of pregnancy, including hyperemesis gravidarum. Optimal diagnostic approaches and management strategies are covered, including which antiemetics are safe to give in pregnancy. Read More

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January 2019
3 Reads

Escherichia coli bacteriuria in pregnant women in Ghana: antibiotic resistance patterns and virulence factors.

BMC Res Notes 2018 Dec 17;11(1):901. Epub 2018 Dec 17.

Department of Medical Laboratory Science, School of Biomedical and Allied Health Sciences, College of Health Sciences, University of Ghana, Legon, Accra, Ghana.

Objectives: The relevance of Escherichia coli associated bacteriuria infection in pregnant women is poorly understood, despite these strains sharing a similar virulence profile with other pathogenic E. coli causing severe obstetric and neonatal infections. We characterized and determined the antimicrobial susceptibility, resistance genes and virulence profiles of 82 E. Read More

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http://dx.doi.org/10.1186/s13104-018-3989-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296117PMC
December 2018
11 Reads

Successful preterm pregnancy in a rare variation of Herlyn-Werner-Wunderlich syndrome: a case report.

BMC Pregnancy Childbirth 2018 Dec 17;18(1):498. Epub 2018 Dec 17.

Department of Woman's and Child's Health, Obstetrics and Gynecological Unit, San Camillo-Forlanini Hospital, Circonvallazione Gianicolense 87, 00152, Rome, Italy.

Background: Herlyn-Werner-Wunderlich syndrome (HWWS) is an uncommon congenital anomaly of the female urogenital tract, characterised by uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. We reported the difficult pregnancy course complicated by an extremely rare and unique case of this syndrome associated with ectrodactyly, a clinical combination never described in literature.

Case Presentation: A 28- year-old nulliparous woman previously diagnosed for HWWS associated with ectrodactyly of the right foot and with a history of abdominal left hemi-hysterectomy, ipsilateral salpingectomy, vaginal reconstruction when she was an adolescent. Read More

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http://dx.doi.org/10.1186/s12884-018-2133-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296152PMC
December 2018
7 Reads

Common Bacterial and Viral Infections: Review of Management in the Pregnant Patient.

Ann Pharmacother 2018 Dec 17:1060028018817935. Epub 2018 Dec 17.

1 University of South Carolina College of Pharmacy, Columbia, SC, USA.

Objective: To review the treatment of common bacterial and viral infections occurring in the pregnant patient.

Data Sources: A literature search of MEDLINE was performed (inception to October 2018). The Centers for Disease Control and Prevention website was utilized for additional information. Read More

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http://dx.doi.org/10.1177/1060028018817935DOI Listing
December 2018
14 Reads

Effect of population-based antenatal screening and treatment of genitourinary tract infections on birth outcomes in Sylhet, Bangladesh (MIST): a cluster-randomised clinical trial.

Lancet Glob Health 2019 Jan;7(1):e148-e159

International Center for Maternal and Newborn Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address:

Background: One-third of preterm births are attributed to pregnancy infections. We implemented a community-based intervention to screen and treat maternal genitourinary tract infections, with the aim of reducing the incidence of preterm birth.

Methods: We did an unblinded cluster-randomised controlled trial in two subdistricts of Sylhet, Bangladesh. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S2214109X183044
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http://dx.doi.org/10.1016/S2214-109X(18)30441-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293967PMC
January 2019
7 Reads

A Mediterranean Diet with an Enhanced Consumption of Extra Virgin Olive Oil and Pistachios Improves Pregnancy Outcomes in Women Without Gestational Diabetes Mellitus: A Sub-Analysis of the St. Carlos Gestational Diabetes Mellitus Prevention Study.

Ann Nutr Metab 2019 14;74(1):69-79. Epub 2018 Dec 14.

Department of Endocrinology and Nutrition, Hospital Clínico Universitario San Carlos and Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain,

Aims: The aim of the study was to evaluate the effect of a Mediterranean diet (MedDiet), enhanced with extra virgin olive oil (EVOO) and nuts, on a composite of adverse maternofoetal outcomes of women with normoglycemia during pregnancy.

Methods: This was a sub-analysis of the St Carlos gestational diabetes mellitus Prevention Study. Only normoglycemic women were analysed (697). Read More

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https://www.karger.com/Article/FullText/495793
Publisher Site
http://dx.doi.org/10.1159/000495793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425818PMC
December 2018
24 Reads

Ultrasound screening for pyelectasis in pregnant women. Clinical necessity or "art for art's sake"?

Authors:
Piotr Szkodziak

J Ultrason 2018 ;18(73):152-157

3rd Department of Gynecology, Medical University of Lublin, Lublin, Poland.

Renal pelvicalyceal dilatation is caused by urine retention in the upper urinary tract. It is referred to as pyelectasis in medical literature. This term does not indicate the cause that leads to the dilatation of and urine retention in the renal pelvicalyceal system. Read More

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http://dx.doi.org/10.15557/JoU.2018.0022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440516PMC
January 2018
20 Reads

A randomized clinical trial comparing Nitrofurazone-coated and uncoated urinary catheters in kidney transplant recipients: Results from a pilot study.

Transpl Infect Dis 2019 Apr 5;21(2):e13031. Epub 2018 Dec 5.

Infectious Diseases Division, Internal Medicine Department, Universidade Federal de São Paulo, São Paulo, Brazil.

Background: Urinary tract infections are frequent complications early after kidney transplantation, and the use of antimicrobial coated catheters in settings other than transplantation has shown promising results for infection prevention. The purpose of this study was to compare the efficacy of Nitrofurazone-coated silicone urinary catheters with non-impregnated silicone urinary catheters in reducing bacteriuria and urinary tract infections in kidney transplant recipients.

Methods: This single-center study, randomized controlled trial at the Hospital do Rim, a tertiary referral center in kidney transplantation, located in São Paulo, Brazil. Read More

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http://dx.doi.org/10.1111/tid.13031DOI Listing
April 2019
6 Reads

Bacterial profile, antibiotic susceptibility pattern and associated factors among pregnant women with Urinary Tract Infection in Goba and Sinana Woredas, Bale Zone, Southeast Ethiopia.

BMC Res Notes 2018 Nov 8;11(1):799. Epub 2018 Nov 8.

Department of Biochemistry, School of Medicine, Goba Referral Hospital, Madda Walabu University, P.O. Box 302, Bale Robe, Ethiopia.

Objective: Urinary tract infection (UTI) is one of the commonest infections affecting millions worldwide, especially pregnant women. It can lead to poor maternal and perinatal outcomes. Untreated UTI can be associated with serious obstetric complications. Read More

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http://dx.doi.org/10.1186/s13104-018-3910-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225670PMC
November 2018
2 Reads

Maternal genitourinary infections and risk of birth defects in the National Birth Defects Prevention Study.

Birth Defects Res 2018 11 6;110(19):1443-1454. Epub 2018 Nov 6.

Congenital Malformations Registry, New York State Department of Health, Albany, New York.

Background: Genitourinary infections (GUIs) are common among sexually active women. Yet, little is known about the risk of birth defects associated with GUIs.

Methods: Using data from the National Birth Defects Prevention Study, a multisite, population-based, case-control study, we assessed self-reported maternal GUIs in the month before through the third month of pregnancy (periconception) from 29,316 birth defect cases and 11,545 unaffected controls. Read More

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http://doi.wiley.com/10.1002/bdr2.1409
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http://dx.doi.org/10.1002/bdr2.1409DOI Listing
November 2018
8 Reads

Obstetrical Outcomes in Adult Patients Born with Complex Anorectal Malformations and Cloacal Anomalies: A Literature Review.

J Pediatr Adolesc Gynecol 2019 Feb 24;32(1):7-14. Epub 2018 Oct 24.

Nationwide Children's Hospital, Columbus, Ohio.

Patients born with complex anorectal malformations often have associated Müllerian anomalies, which might affect fertility and obstetrical outcomes. Other vertebral-anorectal-tracheoesophageal-renal-limb associations, such as renal or cardiac anomalies, could also affect pregnancy intention, fertility rates, and recommendations about mode of delivery or obstetrical outcomes. Associated conditions present at birth, like hydrocolpos, could also potentially affect fertility. Read More

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http://dx.doi.org/10.1016/j.jpag.2018.10.002DOI Listing
February 2019
23 Reads

Prevalence, antimicrobial susceptibility profile and predictors of asymptomatic bacteriuria among pregnant women in Adigrat General Hospital, Northern Ethiopia.

BMC Res Notes 2018 Oct 19;11(1):740. Epub 2018 Oct 19.

Department of Medical Microbiology, Immunology and Parasitology, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.

Objective: Approach to asymptomatic bacteriuria among pregnant women in Ethiopia is mainly based on clinical grounds and urine strip and microscopy tests. On top of this, the treatment is also on an empirical basis which may leads to an increased antimicrobial resistance. The aim of this study was to assess the prevalence, antimicrobial susceptibility profile and associated factors of asymptomatic bacteriuria among pregnant women attending antenatal clinic in Adigrat Hospital, Northern Ethiopia. Read More

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http://dx.doi.org/10.1186/s13104-018-3844-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194591PMC
October 2018
3 Reads

Randomized trial of the efficacy of intravaginal ulinastatin administration for the prevention of preterm birth in women with a singleton pregnancy and both cervical shortening and inflammation of lower genital tract.

J Obstet Gynaecol Res 2019 Jan 11;45(1):86-95. Epub 2018 Sep 11.

Japanese Organization of Prevention of Preterm Delivery (JOPP) Tokyo, Tokyo, Japan.

Aim: To assess the preventive effect on preterm birth of intravaginal ulinastatin (urinary trypsin inhibitor; UTI) administration during the mid-trimester in women with singleton pregnancy and both cervical shortening and lower genital infections.

Methods: Pregnant women with a short cervical length < 25 mm between 16 and 26 weeks of gestation and who had been diagnosed with a lower genital infection were randomly assigned for intravaginal UTI administration or placebo. All of the women were screened for infection or inflammation of the lower genital tract, and women with negative results were excluded. Read More

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http://dx.doi.org/10.1111/jog.13796DOI Listing
January 2019
6 Reads

Vagino-rectal colonization and maternal-neonatal transmission of Enterobacteriaceae producing extended-spectrum β-lactamases or carbapenemases: a cross-sectional study.

J Hosp Infect 2019 Feb 22;101(2):167-174. Epub 2018 Sep 22.

Unidad de Gestión Clínica de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospital Universitario Virgen Macarena de Sevilla/Departamentos de Medicina y Microbiología, Universidad de Sevilla/Instituto de Biomedicina de Sevilla (IBiS), Seville, Spain.

This study sought to determine the prevalence and risk factors for colonization with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) and carbapenemase-producing Enterobacteriaceae (CPE) in 815 mothers and 800 newborns using a cross-sectional design; 59 women and 13 neonates were colonized by ESBL-E (prevalence (95% confidence interval): 6.7% (5.2-8. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956701183048
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http://dx.doi.org/10.1016/j.jhin.2018.09.010DOI Listing
February 2019
14 Reads

Recurrent Abdominal Pain in Children.

Am Fam Physician 2018 Jun;97(12):785-793

University of Missouri School of Medicine, Columbia, MO, USA.

Recurrent abdominal pain (RAP) in children is defined as at least three episodes of pain that occur over at least three months and affect the child's ability to perform normal activities. RAP is most often considered functional (nonorganic) abdominal pain, but an organic cause is found in 5% to 10% of cases. Further workup is warranted in children who have RAP and fever, vomiting, blood in the stool, more than three alarm symptoms, or a history of urinary tract infections. Read More

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June 2018
6 Reads

The association between urinary tract infection during pregnancy and preeclampsia: A meta-analysis.

Medicine (Baltimore) 2018 Sep;97(36):e12192

Department of Obstetrics and Gynecology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Objective: The association between urinary tract infection (UTI) during pregnancy and preeclampsia (PE) continues to be the subject of debate. This meta-analysis aimed to examine the relationship between UTI during pregnancy and PE.

Study Design: Observational studies up to October 2017, extracted from Medline, PubMed, Cochrane Library, and Embase databases, were included in the analysis. Read More

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http://dx.doi.org/10.1097/MD.0000000000012192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133609PMC
September 2018
5 Reads

Pregnancy Related Health Care Needs in Refugees-A Current Three Center Experience in Europe.

Int J Environ Res Public Health 2018 09 5;15(9). Epub 2018 Sep 5.

Department of Clinical Immunology and Rheumatology, Hannover Medical School, 30625 Hannover, Germany.

Immigration into Europe has reached an all-time high. Provision of coordinated healthcare, especially to refugee women that are at increased risk for adverse pregnancy outcomes, is a challenge for receiving health care systems. We assessed pregnancy rates and associated primary healthcare needs in three refugee cohorts in Northern Germany during the current crisis. Read More

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http://dx.doi.org/10.3390/ijerph15091934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165089PMC
September 2018
5 Reads

Infections During Pregnancy.

Prim Care 2018 Sep 9;45(3):567-586. Epub 2018 Jul 9.

Department of Family and Community Medicine, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, USA.

Several infections have unique consequences or considerations in pregnancy. Some common infections such as urinary tract infections, influenza, sexually transmitted diseases, and vaginitis affect pregnant women differently than the general population, can cause pregnancy complications, and require treatments that are safe in pregnancy. Infections such as hepatitis B and C and human immunodeficiency virus can be transmitted vertically and therefore management focuses on decreasing perinatal transmission. Read More

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http://dx.doi.org/10.1016/j.pop.2018.05.013DOI Listing
September 2018
17 Reads

Characterization of Maternal and Neonatal Pharmacokinetic Behavior of Ceftazidime.

J Clin Pharmacol 2019 Jan 16;59(1):74-82. Epub 2018 Aug 16.

Pediatric Pharmacology and Pharmacometrics Research Center, University Children's Hospital Basel, Basel, Switzerland.

Ceftazidime is a parenteral cephalosporin frequently used in pregnant women for treatment of urinary tract or intrauterine infections. Despite its regular use in pregnant women, ceftazidime disposition in both mother and fetus is not well understood, and a pharmacokinetic (PK) model that allows characterization and simulation of both maternal and preterm neonatal ceftazidime disposition is not available. In this study, 10 pregnant women with suspected or proven intrauterine infections in the late second and early third trimester were treated with 1 g of ceftazidime intravenously every 6 hours. Read More

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http://dx.doi.org/10.1002/jcph.1294DOI Listing
January 2019
4 Reads

CARRIAGE OF MULTI-DRUG RESISTANT UROBACTERIA BY ASYMPTOMATIC PREGNANT WOMEN IN YENAGOA, BAYELSA STATE, NIGERIA.

Afr J Infect Dis 2018 18;12(2):14-20. Epub 2018 Jun 18.

Department of Pharmaceutical Microbiology & Biotechnology, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.

Background: Urinary Tract Infections (UTIs) in pregnancy are associated with significant morbidity for both mother and baby but its early detection and treatments can prevent unfavorable complications in pregnancy. This study therefore determined the prevalence of asymptomatic bacteriuria and antimicrobial resistance profile of the urinary bacteria among pregnant women in Yenagoa, Bayelsa State, Nigeria.

Materials And Methods: Mid-stream urine samples were collected from 201 apparently healthy pregnant women attending antenatal clinics in Yenagoa. Read More

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http://dx.doi.org/10.21010/ajid.v12i2.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085741PMC
June 2018
8 Reads

Sepsis in the Obstetric Client.

Authors:
Marie Adorno

Crit Care Nurs Clin North Am 2018 Sep 13;30(3):415-422. Epub 2018 Jul 13.

Department of Nursing, LSU Health New Orleans School of Nursing, 1900 Gravier Street, New Orleans, LA 70112, USA. Electronic address:

Maternal sepsis is the third most common direct cause of maternal mortality following maternal hemorrhage and maternal hypertension. Undetected and poorly managed maternal infections can lead to sepsis, death, or disability for the mother and an increased likelihood of early neonatal infection and other adverse outcomes. When caring for obstetric patients, it is important to identify the stages of antepartum, intrapartum, and postpartum care. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08995885183095
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http://dx.doi.org/10.1016/j.cnc.2018.05.012DOI Listing
September 2018
15 Reads

Mechanical dilatation of the cervix during elective caeserean section before the onset of labour for reducing postoperative morbidity.

Cochrane Database Syst Rev 2018 08 10;8:CD008019. Epub 2018 Aug 10.

Epidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand, 90110.

Background: During elective (planned) caesarean sections, some obstetricians routinely dilate the cervix intraoperatively, using sponge forceps, a finger, or other instruments, because the cervix of women not in labour may not be dilated, and this may cause obstruction of blood or lochia drainage. However, mechanical cervical dilatation during caesarean section may result in contamination by vaginal micro-organisms during dilatation, and increase the risk of infection or cervical trauma.

Objectives: To determine the effects of mechanical dilatation of the cervix during elective caesarean section on postoperative morbidity. Read More

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http://dx.doi.org/10.1002/14651858.CD008019.pub3DOI Listing
August 2018
11 Reads

Neonatal Sepsis of Early Onset, and Hospital-Acquired and Community-Acquired Late Onset: A Prospective Population-Based Cohort Study.

J Pediatr 2018 10 24;201:106-114.e4. Epub 2018 Jul 24.

Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Faculty of Medicine, The University of Queensland, Brisbane, Australia; Paediatric Critical Care Research Group, Mater Research Institute, The University of Queensland, Brisbane, Australia; Paediatric Intensive Care Unit, Lady Cilento Children's Hospital, Children's Health Queensland, Brisbane, Australia.

Objective: To assess the epidemiology of blood culture-proven early- (EOS) and late-onset neonatal sepsis (LOS).

Study Design: All newborn infants admitted to tertiary care neonatal intensive care units in Switzerland and presenting with blood culture-proven sepsis between September 2011 and December 2015 were included in the study. We defined EOS as infection occurring <3 days after birth, and LOS as infection ≥3 days after birth. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00223476183076
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http://dx.doi.org/10.1016/j.jpeds.2018.05.048DOI Listing
October 2018
9 Reads

Prophylactic antibiotics for the prevention of infection following operative vaginal delivery (ANODE): study protocol for a randomised controlled trial.

Trials 2018 Jul 24;19(1):395. Epub 2018 Jul 24.

National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Old Road Campus, Oxford, OX3 7LF, UK.

Background: Sepsis is one of the most important causes of maternal death and severe morbidity worldwide. Studies conducted both in the UK and US have documented an additional risk associated with operative vaginal delivery. However, a Cochrane review, updated in 2017, identified only one small trial of prophylactic antibiotics following operative vaginal delivery, which included a total of 393 women. Read More

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http://dx.doi.org/10.1186/s13063-018-2787-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056933PMC
July 2018
8 Reads

[Comparative effectivenesss of standard antibiotic therapy and Canephron N asymptomatic bacteriuria in pregnant women].

Authors:
K L Lokshin

Urologiia 2018 Jul(3):54-57

Clinical hospital Lapino, Lapino, Moscow region, Russia.

Current international and Russian clinical guidelines recommend treating asymptomatic bacteriuria in pregnancy to prevent acute gestational pyelonephritis. At the same time, the growing resistance of uropathogens and the risks associated with antibiotic therapy in pregnancy dictate the need to limit the use of antibiotics and seek alternative approaches to antibacterial therapy.

Materials And Methods: A retrospective analysis was performed on 60 pregnant women who received either a standard antibiotic regimen (n=32) or the herbal preparation Canephron N (n=28). Read More

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July 2018
5 Reads

Poverty and Community-Acquired Antimicrobial Resistance with Extended-Spectrum β-Lactamase-Producing Organisms, Hyderabad, India.

Emerg Infect Dis 2018 08;24(8):1490-1496

The decreasing effectiveness of antimicrobial agents is a global public health threat, yet risk factors for community-acquired antimicrobial resistance (CA-AMR) in low-income settings have not been clearly elucidated. Our aim was to identify risk factors for CA-AMR with extended-spectrum β-lactamase (ESBL)-producing organisms among urban-dwelling women in India. We collected microbiological and survey data in an observational study of primigravidae women in a public hospital in Hyderabad, India. Read More

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http://dx.doi.org/10.3201/eid2408.171030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056104PMC
August 2018
3 Reads

Maternal and perinatal complications in pregnant women with urinary tract infection caused by Escherichia coli.

J Obstet Gynaecol Res 2018 Aug 5;44(8):1384-1390. Epub 2018 Jul 5.

Research Department , Women's Hospital, Secretariat of Health, Sinaloa, Mexico.

Aim: The incidence of urinary tract infection (UTI) in pregnant women may vary from 5-10% and depends on parity, race, socioeconomic status and anatomical and functional changes in pregnancy. In Mexico, preterm birth accounts for 75% of perinatal deaths and 50% of the neurological sequelae attributable directly to prematurity. The objective of the present study is to describe maternal and perinatal complications in pregnant women with UTI caused by Escherichia coli and to find out the antimicrobial susceptibility pattern. Read More

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http://dx.doi.org/10.1111/jog.13687DOI Listing
August 2018
6 Reads
0.931 Impact Factor

Incidence of postpartum infection, outcomes and associated risk factors at Mbarara regional referral hospital in Uganda.

BMC Pregnancy Childbirth 2018 Jun 28;18(1):270. Epub 2018 Jun 28.

Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.

Background: There is a paucity of recent prospective data on the incidence of postpartum infections and associated risk factors in sub-Saharan Africa. Retrospective studies estimate that puerperal sepsis causes approximately 10% of maternal deaths in Africa.

Methods: We enrolled 4231 women presenting to a Ugandan regional referral hospital for delivery or postpartum care into a prospective cohort and measured vital signs postpartum. Read More

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http://dx.doi.org/10.1186/s12884-018-1891-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022296PMC
June 2018
22 Reads
2.190 Impact Factor

Meropenem/vaborbactam (Vabomere) for complicated urinary tract infection.

Authors:

Med Lett Drugs Ther 2018 06;60(1549):103-105

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June 2018
3 Reads

Assessing the value of Western Cape Provincial Government health administrative data and electronic pharmacy records in ascertaining medicine use during pregnancy.

S Afr Med J 2018 Apr 25;108(5):439-443. Epub 2018 Apr 25.

Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, South Africa.

Background: In African settings, where there is a high disease burden, there is a need to improve the science of documenting and analysing accurate information regarding medicine exposures in women immediately before and during pregnancy to assess the extent of use and safety in pregnant women and their unborn children.

Objectives: To compare evidence of medicine use during pregnancy, as documented in paper-based clinical records (maternity case records (MCRs)) against electronic health information resources (Provincial Health Data Centre (PHDC)) and assess the level of concordance between the two as part of baseline investigations before piloting a provincial pregnancy exposure registry and birth defect surveillance system. The PHDC consolidates electronic clinical and pharmacy data. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039120PMC
http://dx.doi.org/10.7196/SAMJ.2018.v108i5.12879DOI Listing
April 2018
1 Read

A survey of the views and capabilities of community pharmacists in Western Australia regarding the rescheduling of selected oral antibiotics in a framework of pharmacist prescribing.

PeerJ 2018 7;6:e4726. Epub 2018 May 7.

School of Pharmacy, Curtin University, Perth, Western Australia, Australia.

Background: Antibiotic misuse in the community contributes to antimicrobial resistance. One way to address this may be by better utilizing community pharmacists' skills in antibiotic prescribing. The aims of this study were to examine the level of support for "down-scheduling" selected antibiotics and to evaluate factors determining the appropriateness of community pharmacist prescribing for a limited range of infections, including their decision to refer to a doctor. Read More

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https://peerj.com/articles/4726
Publisher Site
http://dx.doi.org/10.7717/peerj.4726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944433PMC
May 2018
16 Reads