3,987 results match your criteria Pregnancy Urinary Tract Infections


The efficacy of pivmecillinam in oral step-down treatment in hospitalised patients with E. coli bacteremic urinary tract infection; a single-arm, uncontrolled treatment study.

BMC Infect Dis 2022 May 19;22(1):478. Epub 2022 May 19.

Department of Infectious Diseases, Vestfold Hospital Trust, Postbox 2168, 3103, Tønsberg, Norway.

Background: The role of oral beta-lactam antibiotics in treating febrile urinary tract infections (UTI) is not yet definite. Today, fluoroquinolones together with trimethoprim-sulfamethoxazole (TMP-MTX) are considered standard of care and often the only available evidence-based oral treatment for febrile UTI. This study clarifies the efficacy and safety of pivmecillinam (PIV) used as step-down therapy for bacteremic urinary tract infection (UTI). Read More

View Article and Full-Text PDF

Demonstrating the utility of Escherichia coli asymptomatic bacteriuria isolates' virulence profile towards diagnosis and management-A preliminary analysis.

PLoS One 2022 6;17(5):e0267296. Epub 2022 May 6.

Medical Education Research and Development Unit (MERDU), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Asymptomatic bacteriuria (ASB) caused by Escherichia coli (E. coli) is a significant condition associated with pregnancy and is considered as prognostic for the development of symptomatic urinary tract infection (UTI). However, treating all ASB increases the use of antibiotics and leads to the development of multidrug resistance (MDR). Read More

View Article and Full-Text PDF

[Modern algorithm of diagnosis and treatment of acute gestational pyelonephritis in a large industrial city].

Urologiia 2022 May(2):34-42

Perm State Medical University named after E.A. Wagner Academy of Health of the Russian Federation, Perm, Russia.

The Purpose Of The Study: to develop a modern algorithm for the diagnosis and treatment of acute gestational pyelonephritis in a large industrial city and to study the possibilities of phytotherapy as an integral part of this algorithm.

Materials And Methods: The study consisted of two stages and included 629 patients treated over 12 years (2010-2021) in Perm city with a population of 1.1 million people. Read More

View Article and Full-Text PDF

Case Report: Fatal Outcome for a Preterm Newborn With Meningitis Caused by Extended-Spectrum β-Lactamase-Producing Sequence Type 1193.

Front Pediatr 2022 6;10:866762. Epub 2022 Apr 6.

Department of Neonatology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.

Introduction: In this case report, we describe an extended-spectrum beta-lactamase (ESBL) - strain of sequence type (ST) 1193, a novel, virulent, multidrug-resistant (MDR) clone with a rapid global spread. ST 1193 has been more commonly associated with invasive disease than other ESBL- STs. To our knowledge, this is the first known case in Sweden where a newborn died of an ESBL- ST 1193 meningitis. Read More

View Article and Full-Text PDF

Maternal Age and Stage of Pregnancy as Determinants of UTI in Pregnancy: A Case of Tamale, Ghana.

Infect Dis Obstet Gynecol 2022 12;2022:3616028. Epub 2022 Apr 12.

Department of Surgery, Tamale Teaching Hospital, P.O. Box TL 16, Tamale, Ghana.

Introduction: Urinary tract infection (UTI) is the world's second most common cause of death, trailing only respiratory tract infections. Because of anatomical and physiological changes along the urinary tract, pregnant women accounted for approximately 20% of all cases of urinary tract infection.

Aim: This study sought to assess maternal age and stage of pregnancy as determinants of UTI among pregnant women in Tamale. Read More

View Article and Full-Text PDF

A Study of Role of Ngal in Diagnosis and Staging the Severity of Diabetic Nephropathy in Type 2 Diabetes Mellitus Patients in Sms Medical College, Jaipur.

J Assoc Physicians India 2022 Apr;70(4):11-12

Sms Medical College, Jaipur.

Present work was conducted to study of role of NGAL in diagnosis and staging the severity of diabetic nephropathy in type 2 diabetes mellitus patients to assess serum NGAL, urine albumin levels in diabetic patients with and without apparent nephropathy.

Material: Comparative study conducted in the General Medicine department of SMS Hospital.

Inclusion Criteria: Patients of type 2 Diabetes mellitus. Read More

View Article and Full-Text PDF

Factors associated with preterm birth among mothers who gave birth at public Hospitals in Sidama regional state, Southeast Ethiopia: Unmatched case-control study.

PLoS One 2022 20;17(4):e0265594. Epub 2022 Apr 20.

College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

Background: Preterm birth remains the commonest cause of neonatal mortality, and morbidity representing one of the principal targets of neonatal health care. Ethiopia is one of the countries which shoulder the highest burden of preterm birth. Therefore, this study was aimed to assess factors associated with preterm birth at public hospitals in Sidama regional state. Read More

View Article and Full-Text PDF

Adherence to the Mediterranean Diet in Pregnancy and Its Benefits on Maternal-Fetal Health: A Systematic Review of the Literature.

Front Nutr 2022 31;9:813942. Epub 2022 Mar 31.

Department of Nursing, University of Alicante, Alicante, Spain.

Introduction: Pregnancy is a transcendent period for the mother and the fetus, characterized by an increase on energy requirements. Mediterranean diet (MD) is considered a healthy eating pattern that can provide the nutritional requirements of pregnancy and protect from the development of obstetric pathologies.

Objective: To know the relationship between adherence to the MD and its maternal-fetal benefits. Read More

View Article and Full-Text PDF

Tobacco Exposure During Pregnancy and Infections in Infants up to 1 Year of Age: The Japan Environment and Children's Study.

J Epidemiol 2022 Apr 9. Epub 2022 Apr 9.

Fukushima Regional Center for the Japan Environmental and Children's Study.

Background: Tobacco exposure during pregnancy is associated with several adverse outcomes in infants. We investigated the association between tobacco exposure during pregnancy (both active and second-hand) and various infections in infants up to 1 year.

Methods: This prospective cohort study used a fixed dataset (jecs-an-20180131) from the Japan Environment and Children's Study of registered births in Japan during 2011-2014 that included 104,065 fetal records from enrolled pregnant women. Read More

View Article and Full-Text PDF

Virulence gene mutations as a differentiator of clinical phenotypes: insights from community-acquired uropathogenic .

Microbiology (Reading) 2022 04;168(4)

Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.

Uropathogenic (UPEC) remains an important cause of urinary tract infection during pregnancy. Multiple molecular virulence determinants and antibiotic resistant genes facilitate its pathogenesis and virulence phenotype. Hence it is hypothesized that there will be considerable variation in genes among the isolates from symptomatic as well as asymptomatic bacteriuria (ABU) during pregnancy. Read More

View Article and Full-Text PDF

Estimation of invasive Group B Streptococcus disease risk in young infants from case-control serological studies.

BMC Med Res Methodol 2022 03 27;22(1):85. Epub 2022 Mar 27.

Statistics and Decision Sciences, Janssen Pharmaceuticals R & D, High Wycombe, United Kingdom.

Background: Group B Streptococcus (GBS) infections are a major cause of invasive disease (IGbsD) in young infants and cause miscarriage and stillbirths. Immunization of pregnant women against GBS in addition to intrapartum antibiotic prophylaxis could prevent disease. Establishing accurate serological markers of protection against IGbsD could enable use of efficient clinical trial designs for vaccine development and licensure, without needing to undertake efficacy trials in prohibitively large number of mother-infant dyads. Read More

View Article and Full-Text PDF

Reduction of intrapartum antibiotic prophylaxis by combining risk factor assessment with a rapid bedside intrapartum polymerase chain reaction testing for group B streptococci.

Eur J Obstet Gynecol Reprod Biol 2022 May 18;272:173-176. Epub 2022 Mar 18.

Department of Gynecology and Obstetrics, Kolding Sygehus, University Hospital of Southern Denmark, Sygehusvej 24, 6000 Kolding, Denmark.

Objective: To investigate the impact of administering Intrapartum Antibiotic Prophylaxis (IAP) to laboring women with one or more risk factors for Early Onset Group B Streptococcal neonatal infection (EOGBS) based on the result of a rapid bedside test for Group B Streptococci (GBS).

Study Design: Quality assessment study.

Methods: Three-hundred-sixty-six laboring women admitted to our maternity ward, with one or more risk factors for EOGBS, were prospectively included. Read More

View Article and Full-Text PDF

PECULIARITIES OF DISTRIBUTION OF ANTIBIOTIC RESISTANT STRAINS OF E. COLI - E. FAECALIS ASSOCIATION IN THE UROGENITAL TRACT OF PREGNANT WOMEN.

Wiad Lek 2022 ;75(2):462-468

OLES HONCHAR DNIPRO NATIONAL UNIVERSITY, DNIPRO, UKRAINE.

Objective: The aim: To investigate the prevalence of antibiotic-resistant strains from the association of E. coli - E. faecalis in the urogenital tract of pregnant women. Read More

View Article and Full-Text PDF

Adolescent pregnancy outcomes at Queen Elizabeth Central Hospital, Malawi: a cross-sectional study.

Malawi Med J 2021 12;33(4):261-268

Kamuzu University of Health Sciences, Malawi.

Malawi has a growing population with a high Maternal Mortality Ratio (MMR) of 439 per 100,000 live births to which adolescents contribute 25%. Current data suggests adolescent pregnancies in low resource settings are at an increased risk of both maternal and neonatal morbidity.

Objectives: This study assessed the pregnancy outcomes amongst adolescents while using women from the early adulthood (20 - 24-year-old) and advanced maternal age (35 years old and above) groups as reference. Read More

View Article and Full-Text PDF
December 2021

Maternal and neonatal outcomes among pregnant women with inflammatory myopathies.

J Perinat Med 2022 Mar 14. Epub 2022 Mar 14.

Department of Obstetrics & Gynecology, Jewish General Hospital, McGill University, Montreal, QC, Canada.

Objectives: Pregnancy outcomes in women with inflammatory myopathies (IM) are not well studied. The purpose of this study is to evaluate the effects of IM on maternal and neonatal outcomes.

Methods: We conducted a retrospective cohort study using data from the Healthcare Cost and Utilization Project - Nationwide Inpatient Sample (HCUP-NIS) from 1999 to 2015. Read More

View Article and Full-Text PDF

Antimicrobial Resistance Pattern in E. coli Isolated from Placental Tissues of Pregnant Women in Low-Socioeconomic Setting of Pakistan.

Curr Microbiol 2022 Feb 5;79(3):83. Epub 2022 Feb 5.

Public Health and Microbiology Lab, Department of Biosciences, COMSATS University Islamabad, Park road, Tarlai Kalan, Islamabad, Pakistan.

Infections during pregnancy can culminate in adverse pregnancy outcomes, including preterm birth (PTB). Pakistan is among the top ten nations with high PTB-associated neonatal mortality rates, where access to prenatal as well as neonatal care is only afforded by the privileged few. Societal stigma further discourages women seeking healthcare for minor infections. Read More

View Article and Full-Text PDF
February 2022

Prevalence and antimicrobial susceptibility pattern of urinary tract infection among pregnant women attending Hargeisa Group Hospital, Hargeisa, Somaliland.

Sci Rep 2022 01 26;12(1):1419. Epub 2022 Jan 26.

Hawassa University College of Medicine and Health Science, Hawassa, Ethiopia.

The aim of this study was to determine the prevalence, antimicrobial susceptibility pattern and associated factors of urinary tract infection (UTI) among pregnant women attending Hargeisa Group Hospital (HGH), Hargeisa, Somaliland. A cross-sectional study was conducted at HGH, Hargeisa, Somaliland and participants were selected by systematic random sampling technique. Clean catch midstream urine samples were collected from 422 participants and cultured and antimicrobial susceptibility pattern was determined for the isolates. Read More

View Article and Full-Text PDF
January 2022

Solitary tubercular renal cyst in a postpartum lady masquerading as an infected giant renal cyst with urosepsis.

Indian J Pathol Microbiol 2022 Jan-Mar;65(1):170-172

Department of Urology, Sri Narayani Hospital and Research Centre, Vellore, Tamil Nadu, India.

Renal tuberculosis presenting as renal cyst is rare. Diagnosing renal tuberculosis in pregnancy is usually delayed due to its atypical presentation. We present a 28-year-old postpartum lady who delivered a healthy baby one month back, with history of intermittent fever and chills. Read More

View Article and Full-Text PDF
February 2022

How to avoid drug resistance during treatment and prevention of urinary tract infections.

Prz Menopauzalny 2021 Dec 9;20(4):217-221. Epub 2021 Dec 9.

1 Department of Obstetrics and Gynaecology, Medical University of Warsaw, Warsaw, Poland.

Urinary tract infections (UTIs), defined as the presence of bacteria above the bladder sphincter, are among the most common infectious diseases. They remain a significant cause of antibiotic prescription worldwide. The incidence is much higher among women, especially of reproductive age, than among men. Read More

View Article and Full-Text PDF
December 2021

Second Trimester Fetal Loss Due to Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM).

Diagnostics (Basel) 2022 Jan 10;12(1). Epub 2022 Jan 10.

Clinical Microbiology Laboratory, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.

is a facultative anaerobic, motile, non-spore-forming Gram-negative bacillus, which belongs to the family of Enterobacteriaceae. Severe infections due to spp. have been reported in the urinary tract, respiratory airways, intra-abdominal organs, skin and soft tissue, eye, bone, bloodstream, and central nervous system. Read More

View Article and Full-Text PDF
January 2022

Association between contraceptive use and risk of lower urinary tract infection (LUTI): A case-control study.

Int J Clin Pharmacol Ther 2022 Apr;60(4):167-175

Aim: The aim of this study was to analyze the association between widely used contraceptive methods and the manifestation of lower urinary tract infections (LUTI) in patients treated in gynecological practices in Germany.

Materials And Methods: This study was based on IQVIA Disease Analyzer database and includes a total of 133,638 females aged between 16 and 50 years who received an initial diagnosis of LUTI including cystitis (ICD-10: N39.0, N30. Read More

View Article and Full-Text PDF

Single-dose antibiotic therapy for urinary infections during pregnancy: A systematic review and meta-analysis of randomized clinical trials.

Int J Gynaecol Obstet 2022 Jan 7. Epub 2022 Jan 7.

Faculty of Medicine, Universidade Federal do Rio Grande do Sul (UFGRS), Porto Alegre, Brazil.

Background: During pregnancy, urinary infections are an important cause of maternofetal morbidity and mortality and may lead to several complications.

Objective: To verify whether the use of antibiotic therapy in a single dose when compared with multiple doses in lower tract urinary infections during pregnancy is effective to obtain microbiologic cure.

Search Strategy: Online databases were searched. Read More

View Article and Full-Text PDF
January 2022

Trends in the epidemiology of urinary tract infections in pregnancy at a tertiary hospital in Johannesburg: Are contemporary treatment recommendations appropriate?

S Afr J Infect Dis 2021 9;36(1):328. Epub 2021 Dec 9.

Department of Clinical Microbiology and Infectious Diseases, University of the Witwatersrand, Johannesburg, South Africa.

Background: Urinary tract infections (UTIs) are common during pregnancy and are associated with maternal and foetal complications. Empiric antibiotic choices in pregnancy require consideration of efficacy and safety, resulting in limited oral options. With rapidly evolving antibiotic resistance, surveillance to guide empiric treatment recommendations is essential. Read More

View Article and Full-Text PDF
December 2021

Asymptomatic Bacteriuria, antimicrobial susceptibility pattern and associated risk factors among pregnant women attending antenatal care in Assosa General Hospital, Western Ethiopia.

BMC Microbiol 2021 12 16;21(1):348. Epub 2021 Dec 16.

Department of Pharmacy, College of Health Science, Assosa University, Assosa, Ethiopia.

Background: Asymptomatic bacteriuria is a common problem in pregnant women and about 40% of women with untreated asymptomatic bacteriuria during pregnancy develop pyelonephritis, which might lead to low birth weight, premature rupture of membranes, and preterm labour. Therefore, this study aimed to assess the prevalence of asymptomatic bacteriuria, antimicrobial susceptibility pattern of the isolates among pregnant women attending the antenatal care of Assosa general hospital, western Ethiopia.

Methods: A facility-based cross-sectional study was conducted from January to February 2019. Read More

View Article and Full-Text PDF
December 2021

Detection of TEM, AmpC, SHV, CTX-M, and MCR-1 Genes in Gram Negative Isolates of Urinary Tract Infections.

Clin Lab 2021 Dec;67(12)

Background: Urinary tract infection (UTI) is an infection caused by the presence and growth of microorganisms anywhere in the urinary tract. It is usually due to bacteria from the digestive tract which climb the opening of the urethra and begin to multiply to cause infection. However, UTI is more frequent in female than male, because of the short urethra, absence of prostatic secretion, and pregnancy. Read More

View Article and Full-Text PDF
December 2021

Prevalence of Urinary Tract Infection and Its Associated Factors among Pregnant Women in Ethiopia: A Systematic Review and Meta-Analysis.

Biomed Res Int 2021 1;2021:6551526. Epub 2021 Dec 1.

Department of Nursing, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.

Objective: Urinary tract infection (UTI) is the most common bacterial infections during pregnancy. It is associated with different maternal and neonatal adverse outcomes such as low birth weight, preterm birth, still birth, preeclampsia, maternal anemia, sepsis, and amnionitis, even when the infection is asymptomatic. However, in Ethiopia, it is represented with fragmented and inconclusive pocket studies. Read More

View Article and Full-Text PDF
January 2022

AAUS guideline for chlamydial urethritis.

J Infect Chemother 2022 Feb 7;28(2):142-145. Epub 2021 Dec 7.

Department of Infection Control and Laboratory Medicine, Sapporo Medical University School of Medicine, Japan.

Urogenital chlamydial infection is the most common sexually transmitted infection. Many cases of chlamydial infection are reported worldwide every year. Genital chlamydial infection in women can also cause obstetric issues, including infertility and miscarriage. Read More

View Article and Full-Text PDF
February 2022

Use of interrupted time-series analysis to characterise antibiotic prescription fills across pregnancy: a Norwegian nationwide cohort study.

BMJ Open 2021 12 8;11(12):e050569. Epub 2021 Dec 8.

PharmacoEpidemiology and Drug Safety Research Group, Department of Pharmacy, and PharmaTox Strategic Initiative, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway.

Objectives: Antibiotics are the most frequently prescribed medications for pregnant and breastfeeding women. We applied interrupted time-series analysis (ITSA) to describe antibiotic prescription fills patterns in pregnant women and examined recurrent antibiotic fills in subsequent pregnancies.

Designs: A population-based drug utilisation study. Read More

View Article and Full-Text PDF
December 2021

A qualitative interview study on successful pregnancies in women with spina bifida.

J Pediatr Urol 2022 02 12;18(1):3.e1-3.e7. Epub 2021 Nov 12.

Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham, United States.

Background: Improvements in antenatal medicine and surgical management for conditions associated with spina bifida such as hydrocephalus have extended the lifespan for individuals with spina bifida (SB) into adulthood. Decisions and education regarding reproductive care and pregnancies for patients with spina bifida are increasingly important. Pregnancy in these patients can be particularly challenging due to physical limitations, previous abdominal surgery for urinary or bowel management and presence of a ventriculoperitoneal shunt. Read More

View Article and Full-Text PDF
February 2022