10,747 results match your criteria Pregnancy Postpartum Hemorrhage


Risk factors and adverse pregnancy outcomes in older pregnant women with hypertensive disorders of pregnancy.

J Obstet Gynaecol Res 2022 May 21. Epub 2022 May 21.

International Inpatient Department, Zhongshan Hospital Affiliated to Dalian University, Dalian City, Liaoning Province, China.

Background: To assess the independent risk factors and pregnancy outcomes of hypertensive disorders of pregnancy (HDPs) in Chinese advanced age pregnancy women.

Design: Secondary analysis of international published data.

Materials And Methods: PubMed, Web of Science, Scopus, Embase, Cochrane library, and Chinese databases from inception to February 23, 2022 were searched to identify eligible studies. Read More

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Incidence of postpartum hemorrhage and risk factors for recurrence in the subsequent pregnancy.

Arch Gynecol Obstet 2022 May 20. Epub 2022 May 20.

Department of Gynecology and Obstetrics, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark.

Purpose: To assess incidence and risk factors for postpartum hemorrhage (PPH) and identify women at high risk of recurrence in the subsequent pregnancy.

Methods: This register-based study includes data on women from the Capital Region of Denmark with two consecutive deliveries recorded in the Copenhagen Obstetric Database from 2007 to 2020. PPH, defined as a blood loss of 1000 mL or more within 24 h after delivery, was the primary outcome measure. Read More

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Retained products of conception (RPOC) following delivery without placenta previa: Which patients with RPOC show postpartum hemorrhage?

Placenta 2022 May 10;124:12-17. Epub 2022 May 10.

Department of Obstetrics and Gynecology, Mie University School of Medicine, Mie, Japan.

Introduction: To clarify the perinatal outcome of retained products of conception (RPOC) after 22 weeks or more.

Methods: The retrospective cohort study reviewed medical records of patients with RPOC without placenta previa at 186 Japanese perinatal centers.

Results: Of the 323 patients with RPOC, pregnancies after assisted reproductive technology (ART) accounted for 43%. Read More

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Availability, Utilization, and Quality of Basic Emergency Obstetric and Newborn Care Services in Farta District, Rural Health Centers, Ethiopia.

J Health Care Poor Underserved 2022 ;33(2):1094-1106

Background: Emergency obstetric and neonatal care (EmONC) is a cost-effective priority intervention to reduce maternal and neonatal morbidity and mortality in poorresource settings. In most sub-Saharan African countries, all signal functions perform below the appropriate United Nations standard.

Objective: This study aims to assess the availability, utilization, and quality of basic emergency obstetric and newborn care services in Farta District, Ethiopia primary health care centers. Read More

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Postpartum hemorrhage in women with von Willebrand disease: Consider other etiologies.

J Obstet Gynaecol Can 2022 May 12. Epub 2022 May 12.

Division of Hematology, Sinai Health System, Department of Medicine University of Toronto, Toronto, Ontario, Canada.

Objective: Higher rates of postpartum hemorrhage (PPH) have been reported for women with von Willebrand disease (VWD). Comprehensive multidisciplinary care reduces these rates; thus PPH may not be secondary to VWD.

Methods: We conducted a retrospective review for the period of 2009-2018, including all VWD pregnancies at two tertiary care academic hospitals to determine rates, etiology, and timing of PPH. Read More

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Epidemiology, Risk Factors, and Perinatal Outcomes of Placental Abruption-Detailed Annual Data and Clinical Perspectives from Polish Tertiary Center.

Int J Environ Res Public Health 2022 Apr 23;19(9). Epub 2022 Apr 23.

Center of Postgraduate Medical Education, Second Department of Obstetrics and Gynecology, 01-813 Warsaw, Poland.

Placental abruption (PA) is a separation of the placenta from the uterine wall occurring with the fetus still present in the uterine cavity. It contributes to numerous neonatal and maternal complications, increasing morbidity and mortality. We conducted a retrospective study at a tertiary perinatal care center, which included 2210 cases of labor that took place in 2015 with a PA occurrence of 0. Read More

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Unilateral uterine artery embolization and Bakri tamponade balloon insertion in the treatment of acute puerperal uterine inversion: a case report.

J Med Case Rep 2022 May 14;16(1):190. Epub 2022 May 14.

Department of Obstetrics and Gynaecology, University Hospital Mizonokuchi, Teikyo University School of Medicine, 5-1-1 Futago, Takatsu-ku, Kawasaki, Kanagawa, 213-8507, Japan.

Background: Acute puerperal uterine inversion is rare but may cause massive postpartum blood loss due to uterine atony. Therefore, these patients must be diagnosed, and uterine replacement must be performed as soon as possible. However, in some cases, active bleeding due to uterine atony becomes uncontrollable, even though the uterine inversion itself is treated. Read More

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Placental Abruption and Partial Placental Prolapse During Induction of Labor in a 31-Year-Old Female With Intrahepatic Cholestasis of Pregnancy: A Case Report.

Cureus 2022 Apr 9;14(4):e23995. Epub 2022 Apr 9.

Obstetrics/Gynecology, West Suburban Medical Center, Chicago, USA.

Placental abruption during induction of labor in females with intrahepatic cholestasis of pregnancy is not exceptionally common and there are no documented reports of placental prolapse following abruption in the literature. The aim of this study is to discuss the possibility of placental abruption and partial prolapse of a low-lying placenta during a prolonged induction of labor in a female with recurrent intrahepatic cholestasis of pregnancy following a cholecystectomy. We describe a 31-year-old G4P3003 female with recurrent intrahepatic cholestasis of pregnancy, with no family history of the condition and surgical history of cholecystectomy, whose induction of labor at 37+3/7 gestational weeks for intrahepatic cholestasis of pregnancy was complicated by placental abruption and partial prolapse of the low-lying placenta. Read More

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Comparing pregnancy, childbirth, and neonatal outcomes in women with idiopathic polyhydramnios: a prospective cohort study.

BMC Pregnancy Childbirth 2022 May 11;22(1):399. Epub 2022 May 11.

Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.

Background: In this prospective cohort study, the perinatal outcome in idiopathic polyhydramnios compared with normal pregnancies was examined.

Methods: This was a prospective cohort study of 180 singleton pregnancies who received care at the referral gynecology clinic of Yasuj, Iran between 2018-2020. The inclusion criteria comprised singleton pregnancies, gestational age > 34 weeks; fetuses without structural and chromosomal abnormalities in pregnancy screening test, no maternal diabetes, negative TORCH negative screening test, no Rh factor isoimmunization. Read More

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Implementing a Statewide Speakers Bureau to Address Maternal Morbidity and Mortality.

Nurs Womens Health 2022 May 8. Epub 2022 May 8.

Objective: To implement a speakers bureau to educate providers, health caregivers, and staff practicing within Tennessee hospitals on evidence-based practice recommendations related to opioid use disorder in pregnancy, postpartum hemorrhage, maternal hypertension, and implicit bias.

Design: Quality improvement project.

Setting/local Problem: Multiple health care facilities throughout Tennessee, where rates of pregnancy-related mortality are greater than the national average and where Black women are three times as likely as White women to die of pregnancy complications. Read More

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Systematic review and meta-analysis of the effectiveness and perinatal outcomes of COVID-19 vaccination in pregnancy.

Nat Commun 2022 May 10;13(1):2414. Epub 2022 May 10.

Fetal Medicine Unit, St George's Hospital, St George's University of London, London, UK.

Safety and effectiveness of COVID-19 vaccines during pregnancy is a particular concern affecting vaccination uptake by this vulnerable group. Here we evaluated evidence from 23 studies including 117,552 COVID-19 vaccinated pregnant people, almost exclusively with mRNA vaccines. We show that the effectiveness of mRNA vaccination against RT-PCR confirmed SARS-CoV-2 infection 7 days after second dose was 89·5% (95% CI 69·0-96·4%, 18,828 vaccinated pregnant people, I = 73·9%). Read More

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Pregnancy outcomes at advanced maternal age in a tertiary Hospital, Jeddah, Saudi Arabia.

Saudi Med J 2022 May;43(5):491-499

From the Department of Obstetrics and Gynecology, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia.

Objectives: To evaluate obstetrical and fetal outcomes among advanced maternal age (AMA) women.

Methods: Retrospective cohort study carried out at a teaching hospital, Jeddah, Saudi Arabia, during 18 years period (from January 2003 until December 2020). A total of 79095 women gave birth, and randomized block was used to include 4318 singleton pregnancy women (>28 gestational weeks), of them 2162 age ≥40 years. Read More

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Maternal and neonatal outcomes in women with a history of chemotherapy exposure: a population-based study of 8 million obstetric admissions.

Arch Gynecol Obstet 2022 May 7. Epub 2022 May 7.

Department of Obstetrics and Gynecology, Jewish General Hospital, McGill University, Pavilion H, Room 325, 5790 Cote-des-Neiges Road, Montreal, H3S 1Y9, Canada.

Purpose: With improvement in cancer care and fertility preservation, increasing numbers of cancer survivors are requiring obstetrical care. The objective of our study was to evaluate the effect of history of chemotherapy exposure on maternal and neonatal outcomes.

Methods: A retrospective population-based cohort study was conducted using the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample (HCUP-NIS) to obtain data on maternal and newborn outcomes in a cohort of births occurring between the years 2006 and 2015. Read More

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Systematic review and meta-analysis of the efficacy and pregnancy outcomes of levothyroxine sodium tablet administration in pregnant women complicated with hypothyroidism.

Ann Palliat Med 2022 Apr;11(4):1441-1452

Ultrasound Department, Shijiazhuang Fourth Hospital, Shijiazhuang, China.

Background: In recent years, the detection rate of pregnancy complicated with hypothyroidism [subclinical hypothyroidism (SCH) during pregnancy] has increased significantly. Levothyroxine sodium tablet is the main drug for the treatment of SCH during pregnancy, but its effect on the treatment of SCH during pregnancy and the effect of pregnancy outcome are still controversial.

Methods: PubMed, Web of Science, Medline, and Embase databases were screened to retrieve clinical studies on levothyroxine sodium tablets in the treatment of pregnancy complicated with hypothyroidism from the date of establishment to June 2021. Read More

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Big picture initiatives in bleeding disorders.

Haemophilia 2022 May;28 Suppl 4:53-60

CHU Lille, Hematology Transfusion, LILLE, France.

Introduction: The inherited bleeding disorders (IBD) community has witnessed significant therapeutic advances recently, yet important gaps persist, particularly for those with rare disorders and historically underserved populations.

Aims: -To create a national research blueprint agenda, led by the National Hemophilia Foundation (NHF), enhancing patient-centric principles, accelerate research progress and address important gaps in care. -To review critical gaps that remain to be addressed in women with IBDs, who face specific bleeding challenges. Read More

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Quality and outcomes of maternal and perinatal care for 76,563 pregnancies reported in a nationwide network of Nigerian referral-level hospitals.

EClinicalMedicine 2022 May 28;47:101411. Epub 2022 Apr 28.

UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Sexual and Reproductive Health and Research, World Health Organization, Geneva, Switzerland.

Background: The WHO in collaboration with the Nigeria Federal Ministry of Health, established a nationwide electronic data platform across referral-level hospitals. We report the burden of maternal, foetal and neonatal complications and quality and outcomes of care during the first year.

Methods: Data were analysed from 76,563 women who were admitted for delivery or on account of complications within 42 days of delivery or termination of pregnancy from September 2019 to August 2020 across the 54 hospitals included in the Maternal and Perinatal Database for Quality, Equity and Dignity programme. Read More

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Endovascular coiling versus neurosurgical clipping for treatment of ruptured and unruptured intracranial aneurysms during pregnancy and postpartum period.

J Neurointerv Surg 2022 May 4. Epub 2022 May 4.

Departments of Neurology, Neurosurgery, and Radiology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

Background: Selection of appropriate surgical strategy for the treatment of intracranial aneurysms (IA) during pregnancy requires careful consideration of the potential risks to the mother and fetus. However, limited data guide treatment decisions in these patients. We compared the safety profiles of endovascular coiling (EC) and neurosurgical clipping (NC) performed for the treatment of ruptured and unruptured IA during pregnancy and the postpartum period. Read More

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Deferred consent in emergency obstetric research: findings from qualitative interviews with women and recruiters in the pilot trial for severe postpartum haemorrhage.

BMJ Open 2022 May 4;12(5):e054787. Epub 2022 May 4.

Blizard Institute, Queen Mary University of London, London, UK.

Objective: The ACROBAT pilot trial of early cryoprecipitate for severe postpartum haemorrhage used deferred consent procedures. Pretrial discussions with a patient and public involvement group found mixed views towards deferred consent. This study aimed to build an understanding of how the deferred consent procedures worked in practice, to inform plans for a full-scale trial. Read More

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Reassessing the duration of each stage of labor and their relation to postpartum hemorrhage in the current Japanese population.

J Obstet Gynaecol Res 2022 May 3. Epub 2022 May 3.

Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Aim: To reassess the normal duration of each stage of labor in a contemporary Japanese cohort, and to determine whether prolongation of each stage of labor increases the rate of postpartum hemorrhage (PPH) in vaginal deliveries.

Methods: Clinical data of women who delivered at term at 12 facilities between 2012 and 2018 were retrospectively collected. A total of 31 758 women were subdivided into three or four subgroups according to the duration of each stage of labor and parity. Read More

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Continued versus discontinued oxytocin after the active phase of labor: An updated systematic review and meta-analysis.

PLoS One 2022 2;17(5):e0267461. Epub 2022 May 2.

Department of Gynecology, Shenyang Women's and Children's Hospital, Shenyang, Liaoning, China.

Objective: To systematically assess the effect of discontinued vs continued oxytocin after active stage of labour is established.

Methods: Pubmed, Embase, and the Cochrane Library were systematically searched to 18 April 2021. The risk ratio or mean difference with corresponding 95% confidence interval were computed to investigate the effect of intervention or control on maternal and fetus outcomes. Read More

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Secondary Postpartum Hemorrhage Due to Retained Placenta Accreta Spectrum: A Case Report.

Int J Womens Health 2022 22;14:593-597. Epub 2022 Apr 22.

Department of Obstetrics and Gynecology at the University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Background: Retained products of conception and placenta accreta spectrum are causes of postpartum hemorrhage. Placenta accreta spectrum is frequently managed with cesarean hysterectomy, but conservative approaches are emerging. We present a case of delayed postpartum hemorrhage secondary to a retained placenta increta. Read More

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A study on maternal and foetal prognosis and predictive factors for adverse outcome in pregnant patients with dengue in an endemic state of India.

J Family Med Prim Care 2022 Mar 10;11(3):912-917. Epub 2022 Mar 10.

Department of Obg., Tata Main Hospital, Jamshedpur, Jharkhand, India.

Aims: Dengue fever is a major health problem with high morbidity and mortality especially during epidemic season; pregnant females being no exception. But, there is paucity of published data on dengue fever during pregnancy. Hence, this study was planned to study the clinical profile, maternal outcome and predictors of poor outcome in pregnant dengue patients. Read More

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Uterine hemangioma in pregnancy: A case report and review of the literature.

J Gynecol Obstet Hum Reprod 2022 Apr 29;51(6):102401. Epub 2022 Apr 29.

Department of Obstetrics and Gynaecology, Division Woman and Child, University Hospitals Leuven, Herestraat 49, Leuven 3000, Belgium; Department of Development and Regeneration, Cluster Woman and Child, Faculty of Medicine, KU Leuven University, Herestraat 49, Leuven 3000, Belgium. Electronic address:

Introduction: Uterine hemangioma is a rare benign vascular tumor which can cause bleeding problems in various age groups. Current knowledge on this rare condition in pregnancy is limited. We report on a recent case of uterine hemangioma in a pregnancy that was already diagnosed during her first trimester. Read More

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Reproductive Issues in Patients with the Fontan Operation.

Can J Cardiol 2022 Apr 28. Epub 2022 Apr 28.

Division of Cardiology, University of Toronto, Pregnancy and Heart Disease Program, Mount Sinai and Toronto General Hospitals, Toronto, Canada.

Patients with the Fontan operation have a unique circulation with a limited ability to increase cardiac output and high central venous pressure. They may have diastolic and/or systolic ventricular dysfunction, arrhythmias, thromboembolic complications, or multi-organ dysfunction. All of these factors contribute to reproductive issues including menstrual irregularities, infertility, recurrent miscarriage, and complications during pregnancy. Read More

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Incidence and causes of severe maternal outcomes in Somaliland using the sub-Saharan Africa maternal near-miss criteria: A prospective cross-sectional study in a national referral hospital.

Int J Gynaecol Obstet 2022 May 1. Epub 2022 May 1.

Institution of Health and Welfare, Dalarna University, Dalarna, Sweden.

Objective: To describe the incidence and causes of severe maternal outcomes and the unmet need for life-saving obstetric interventions among women admitted for delivery in a referral hospital in Somaliland.

Methods: A prospective cross-sectional study was conducted from April 15, 2019, to March 31, 2020, with women admitted during pregnancy or childbirth or within 42 days after delivery. Data was collected using the World Health Organization (WHO) and sub-Saharan Africa (SSA) maternal near-miss (MNM) tools. Read More

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A risk prediction model of perinatal blood transfusion for patients who underwent cesarean section: a case control study.

BMC Pregnancy Childbirth 2022 Apr 30;22(1):373. Epub 2022 Apr 30.

Department of Obstetrics, The Second Hospital, Cheeloo College of Medicine, Shandong University, No. 247 Beiyuan Road, Jinan, 250033, Shandong, China.

Background: Severe obstetric hemorrhage is a leading cause of severe maternal morbidity. A perinatal blood transfusion is the key factor in the treatment of severe obstetric hemorrhage. Our aim is to identify patients with a high risk of perinatal blood transfusions before Cesarean Section, which can promote the effectiveness of the treatment of severe obstetric hemorrhage, as well as improve obstetric preparations. Read More

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Prolonged operative time of cesarean is a risk marker for subsequent cesarean maternal complications.

Arch Gynecol Obstet 2022 Apr 29. Epub 2022 Apr 29.

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Affiliated with the Hebrew University School of Medicine, 12 Bayit Street, 91031, Jerusalem, Israel.

Purpose: Prolonged cesarean operative time (OT) is a well-established proxy for post-operative maternal complications. We aimed to study whether prolonged OT may serve as a proxy for maternal complications in the subsequent cesarean delivery.

Methods: A retrospective cohort study of women who underwent cesarean delivery between 2005 and 2019. Read More

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Maternal and Neonatal Outcomes After Assisted Reproductive Technology: A Retrospective Cohort Study in China.

Front Med (Lausanne) 2022 5;9:837762. Epub 2022 Apr 5.

Nanjing Maternity and Child Health Care Institute, Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, Nanjing, China.

Background: With the progress of assisted reproductive technology (ART) and the increasing number of ART pregnancy, its safety has become the focus of attention. The present study aimed to explore the associations of ART pregnancy with maternal and neonatal outcomes, as compared with naturally pregnancy.

Methods: This retrospective cohort study included all pregnant women who delivered at Women's Hospital of Nanjing Medical University in 2011-2020. Read More

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Placenta accreta spectrum: a non-oncologic challenge for gynecologic oncologists.

Int J Gynecol Cancer 2022 Apr 27. Epub 2022 Apr 27.

Department of Obstetrics and Gynecology, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.

Placenta accreta spectrum disorders are a major risk factor for severe postpartum hemorrhage and maternal death worldwide, with a rapidly growing incidence in recent decades due to increasing rates of cesarean section. Placenta accreta spectrum disorders represent a complex surgical challenge, with the primary concern of massive obstetrical hemorrhagic sequelae and organ damage, occurring in the context of potentially significant anatomical and physiological changes of pregnancy. Most international obstetrical organizations have published guidelines on placenta accreta spectrum, embracing the creation of regionalized 'Centers of Excellence' in the diagnosis and management of placenta accreta spectrum, which includes a dedicated multidisciplinary surgical team. Read More

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Perinatal outcomes of women with gestational breast cancer in Australia and New Zealand: A prospective population-based study.

Birth 2022 Apr 26. Epub 2022 Apr 26.

Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Western Australia, Australia.

Objective: To determine the epidemiology, clinical management, and outcomes of women with gestational breast cancer (GBC).

Methods: A population-based prospective cohort study was conducted in Australia and New Zealand between 2013 and 2014 using the Australasian Maternity Outcomes Surveillance System (AMOSS). Women who gave birth with a primary diagnosis of breast cancer during pregnancy were included. Read More

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