8,477 results match your criteria Pregnancy Postpartum Hemorrhage


Placental location and pregnancy outcomes in nulliparous women: A population-based cohort study.

Acta Obstet Gynecol Scand 2019 Feb 15. Epub 2019 Feb 15.

Department of Medicine, Solna, Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden.

Introduction: The impact of placenta previa on pregnancy, delivery and infant outcomes has been extensively studied. Less is however known about the possible association of placental location other than previa with pregnancy outcomes. The aim of this study was to investigate if placental location other than previa is associated with adverse pregnancy, delivery and infant outcomes. Read More

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http://dx.doi.org/10.1111/aogs.13578DOI Listing
February 2019

"Not taken seriously"-A qualitative interview study of postpartum Rwandan women who have experienced pregnancy-related complications.

PLoS One 2019 13;14(2):e0212001. Epub 2019 Feb 13.

Department of Clinical Sciences, Obstetrics and Gynaecology, Umeå University, Umeå, Sweden.

Background: There is limited knowledge on the women's experiences of pregnancy-related complications in Rwanda. This study aimed to investigate women's experiences and perceptions of specific complications during pregnancy and delivery and the consequences of these complications on postpartum health and family situation.

Methods: Data were collected through individual in-depth interviews (N = 15). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212001PLOS
February 2019

Active versus expectant management for women in the third stage of labour.

Cochrane Database Syst Rev 2019 Feb 13;2:CD007412. Epub 2019 Feb 13.

School of Nursing and Midwifery, Trinity College Dublin, 24 D'Olier Street, Dublin, Ireland.

Background: Active management of the third stage of labour involves giving a prophylactic uterotonic, early cord clamping and controlled cord traction to deliver the placenta. With expectant management, signs of placental separation are awaited and the placenta is delivered spontaneously. Active management was introduced to try to reduce haemorrhage, a major contributor to maternal mortality in low-income countries. Read More

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http://dx.doi.org/10.1002/14651858.CD007412.pub5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372362PMC
February 2019
2 Reads

Monitoring quality of obstetric care from hospital discharge databases: A Delphi survey to propose a new set of indicators based on maternal health outcomes.

PLoS One 2019 12;14(2):e0211955. Epub 2019 Feb 12.

Inserm UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epopé) Center for Epidemiology and Statistics Sorbonne Paris Cité, DHU Risks in pregnancy, Paris Descartes University, Paris, France.

Objectives: Most indicators proposed for assessing quality of care in obstetrics are process indicators and do not directly measure health effects, and cannot always be identified from routinely available databases. Our objective was to propose a set of indicators to assess the quality of hospital obstetric care from maternal morbidity outcomes identifiable in permanent hospital discharge databases.

Methods: Various maternal morbidity outcomes potentially reflecting quality of obstetric care were first selected from a systematic literature review. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211955PLOS
February 2019
2 Reads

The risk of abnormal placentation and hemorrhage in subsequent pregnancy following primary elective caesarean delivery.

J Matern Fetal Neonatal Med 2019 Feb 10:1-11. Epub 2019 Feb 10.

a International Peace Maternity & Child Health Hospital , School of Medicine , Shanghai Jiao Tong University , Shanghai , China.

Objective: We aimed to evaluate the relationship between mode of first delivery with subsequent placenta previa, placenta accreta/increta and significant postpartum hemorrhage (PPH).

Method: This retrospective cohort study included women with two consecutive singleton deliveries between 2007-2017 at our institution if the women were nulliparous and delivered at term at the time of first delivery. The first pregnancy delivery mode was classified as (1) vaginal delivery, (2) antepartum caesarean delivery (CD) without labor, or (3) intrapartum CD after onset of labor. Read More

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http://dx.doi.org/10.1080/14767058.2019.1581167DOI Listing
February 2019
1 Read

The increasing role of a retained placenta in postpartum blood loss: a cohort study.

Arch Gynecol Obstet 2019 Feb 7. Epub 2019 Feb 7.

Department of Obstetrics, Juliane Marie Centre, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.

Purpose: To describe the association between quantity of blood loss, duration of the third stage of labour, retained placenta and other risk factors, and to describe the role of a retained placenta depending on the cutoff used to define postpartum haemorrhage.

Methods: Cohort study of all vaginal deliveries at two Danish maternity units between 1 January 2009 and 31 December 2013 (n = 43,357), univariate and multivariate linear regression statistical analyses.

Results: A retained placenta was shown to be a strong predictor of quantity of blood loss and duration of the third stage of labour a weak predictor of quantity of blood loss. Read More

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http://dx.doi.org/10.1007/s00404-019-05066-3DOI Listing
February 2019

Maternal and Newborn Outcomes with Elective Induction of Labor at Term.

Am J Obstet Gynecol 2019 Jan 29. Epub 2019 Jan 29.

Department of Obstetrics & Gynecology, Oregon Health & Science University.

Background: A growing body of evidence supports improved or not worsened birth outcomes with non-medically indicated induction of labor at 39 weeks compared to expectant management. This evidence includes two recent randomized control trials. However, concern has been raised as to whether these studies are applicable to a broader US pregnant population. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.223DOI Listing
January 2019
1 Read

Influence of the WOMAN trial on national wide standard operating procedures for treatment of postpartum hemorrhage.

J Gynecol Obstet Hum Reprod 2019 Jan 24. Epub 2019 Jan 24.

University Hospital Frankfurt, Department of Anesthesiology, Intensive Care Medicine, and Pain Therapy, Theodor-Stern Kai 7, 60590 Frankfurt am Main, Germany; Asklepios Hospital Wandsbek, Department of Anesthesiology, Intensive Care Medicine, and Pain Therapy, Alphonsstraße 14, 22043 Hamburg, Germany.

Background: Postpartum hemorrhage is the leading cause of maternal death. Recently, the WOMAN trial showed that early administration of tranexamic acid leads to a reduced mortality due to bleeding. The aim was to study whether the results of the WOMAN trial have influenced the institutional standard operating procedures in treating postpartum hemorrhage. Read More

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http://dx.doi.org/10.1016/j.jogoh.2019.01.010DOI Listing
January 2019
8 Reads

Uterine Artery Pseudoaneurysm: A Life-Threatening Cause of Vaginal Bleeding in the Emergency Department.

J Emerg Med 2019 Jan 23. Epub 2019 Jan 23.

Department of Emergency Medicine, Medical University of South Carolina, Charleston, South Carolina.

Background: Vaginal bleeding is a common presenting complaint in the emergency department (ED); life-threatening hemorrhage is rare. Uterine artery pseudoaneurysm (UAP) is an uncommon but potentially life-threatening cause of vaginal bleeding that is most likely to present primarily to EDs, given its delayed postpartum or postoperative presentation.

Case Report: A 25-year-old female gravida two, para one, who was 19 days post dilation and evacuation for an elective termination of a pregnancy at 20 weeks, presented to the ED with profuse vaginal bleeding. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.12.016DOI Listing
January 2019
3 Reads

Intramuscular injection, intravenous infusion, and intravenous bolus of oxytocin in the third stage of labor for prevention of postpartum hemorrhage: a three-arm randomized control trial.

BMC Pregnancy Childbirth 2019 Jan 18;19(1):38. Epub 2019 Jan 18.

Gynuity Health Projects, 220 East 42nd St, Suite 710, New York, NY, 10010, USA.

Background: Oxytocin for postpartum hemorrhage (PPH) prophylaxis is commonly administered by either intramuscular (IM) injection or intravenous (IV) infusion with both routes recommended equally and little discussion of potential differences between the two. This trial assesses the effectiveness and safety of 10 IU oxytocin administered as IM injection versus IV infusion and IV bolus during the third stage of labor for PPH prophylaxis.

Methods: In two tertiary level Egyptian maternity hospitals, women delivering vaginally without exposure to pre-delivery uterotonics were randomized to one of three prophylactic oxytocin administration groups after delivery of the baby. Read More

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http://dx.doi.org/10.1186/s12884-019-2181-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339323PMC
January 2019
3 Reads

Pregnancy-related acquired hemophilia A initially manifesting as pleural hemorrhage: A case report.

Medicine (Baltimore) 2019 Jan;98(3):e14119

Department of Hematology, First Affiliated Hospital of Zhejiang, Chinese Medical University, Hangzhou, China.

Rationale: Acquired hemophilia A is a rare hemorrhagic disease in which the body produces specific antibodies that attack factor VIII, resulting in bleeding that is mainly mucocutaneous and associated with soft tissue and the gastrointestinal system. Approximately 50% of this disease derives from basic diseases, such as autoimmune diseases, cancer, and pregnancy.

Patient Concerns: We report a 35-year-old postpartum female with acquired hemophilia A who initially presented with pleural hemorrhage. Read More

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http://dx.doi.org/10.1097/MD.0000000000014119DOI Listing
January 2019
4 Reads

Changing trends in the Turkish maternal deaths, with a focus on direct and indirect causes.

Eur J Obstet Gynecol Reprod Biol 2019 Jan 6;234:21-25. Epub 2019 Jan 6.

Turkish Public Health Agency, Preliminary Investigation Committee for Maternal Deaths, Government of Health, Ankara, Turkey.

Objective: Our aim is to evaluate trends in the direct and indirect causes' distribution using data from National Maternal Mortality Surveillance (2012-2015).

Study Design: A population-based retrospective review was performed on all pregnancy-associated maternal deaths in Turkey from 2012 to 2015. Causes of death were grouped into direct and indirect maternal deaths and compared in the context of distribution. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2018.12.031DOI Listing
January 2019
2 Reads
1.627 Impact Factor

Maternal, reproductive and obstetric factors associated with preterm births in Mulago Hospital, Kampala, Uganda: a case control study.

Pan Afr Med J 2018 10;30:272. Epub 2018 Aug 10.

Department of Nursing, College of Health Sciences, Makerere University, Kampala, Uganda.

Introduction: Preterm birth, a leading cause of neonatal mortality accounts for 35 percent of all neonatal deaths worldwide. Uganda's high preterm birth rate of 13.6 per 1000 live births ranks 28 in the world. Read More

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http://www.panafrican-med-journal.com/content/article/30/272
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http://dx.doi.org/10.11604/pamj.2018.30.272.13531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317463PMC
January 2019
5 Reads

Impact of nonpneumatic antishock garment in the management of patients with hypoperfusion due to massive postpartum hemorrhage.

J Matern Fetal Neonatal Med 2019 Jan 22:1-5. Epub 2019 Jan 22.

b Departament of Health Science, Faculty of Medicine , ICESI University , Cali , Colombia.

Objective: The objective of this article was to compare hemodynamic and perfusion parameters as well as the clinical outcomes in critically ill patients with postpartum hemorrhage (PPH) who received treatment with a nonpneumatic antishock garment (NASG) as part of an intervention package, with a group of patients in similar conditions who did not receive an NASG.

Methods: This observational study analyzed a historic cohort of 154 patients with PPH, secondary hypovolemic shock and signs of hypoperfusion who were admitted to this institution from 2012 to 2015. Group 1 (n= 77) was managed with NASG and Group 2 (n = 77) received interventions other than NASG. Read More

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https://www.tandfonline.com/doi/full/10.1080/14767058.2019.1
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http://dx.doi.org/10.1080/14767058.2019.1568982DOI Listing
January 2019
5 Reads

Increased incidence of obstetric and perinatal complications in pregnancies achieved using donor oocytes and single embryo transfer in young and healthy women. A prospective hospital-based matched cohort study.

Gynecol Endocrinol 2019 Jan 9:1-6. Epub 2019 Jan 9.

e Department of Clinical Science, Intervention and Technology , Karolinska Institutet , Stockholm , Sweden.

In this single-center matched-cohort study, women who underwent IVF/ICSI with donor oocytes between 2007 and 2014 (n = 259) were compared to women undergoing autologous cycles during the same time period (n = 515). The matching (1:2) took into consideration the women's age, type of treatment (IVF/ICSI), and year of embryo transfer. All women were healthy and below 40 years of age at the time of IVF/ICSI, and the treatments were performed using a strict policy of single embryo transfer. Read More

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http://dx.doi.org/10.1080/09513590.2018.1528577DOI Listing
January 2019
1 Read

Comprehensive treatment in severe dengue during preterm and term labor: could tocolysis be useful?

J Matern Fetal Neonatal Med 2019 Jan 9:1-6. Epub 2019 Jan 9.

b Clinical Research Center, Fundación Valle Del Lili , Cali , Colombia.

Objective: There is lack of data on the management of severe dengue infection during labor. The objective of this study was to describe our experience in the management of preterm and term labor of pregnant patients with severe dengue infection and thrombocytopenia.

Materials And Methods: We describe patients with dengue infection confirmed by dengue serology or NS1 antigen in Cali, Colombia. Read More

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https://www.tandfonline.com/doi/full/10.1080/14767058.2018.1
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http://dx.doi.org/10.1080/14767058.2018.1554044DOI Listing
January 2019
9 Reads

Incidence and risk factors for postpartum hemorrhage among transvaginal deliveries at a tertiary perinatal medical facility in Japan.

PLoS One 2019 9;14(1):e0208873. Epub 2019 Jan 9.

Department of Obstetrics and Gynecology, ASO Iizuka Hospital, Iizuka, Fukuoka, Japan.

Postpartum hemorrhage (PPH) remains a leading cause of maternal death worldwide, and it is important to understand the relative contributions of different risk factors. We assessed the incidence of these among cases of transvaginal delivery. Between June 2013 and July 2016, a prospective cohort study was conducted at a tertiary perinatal medical facility in Japan. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208873PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326562PMC
January 2019
3 Reads

Heat-Stable Carbetocin to Prevent Postpartum Hemorrhage.

N Engl J Med 2018 12;379(24):2380-2381

University of Liverpool, Liverpool, United Kingdom

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http://dx.doi.org/10.1056/NEJMc1812692DOI Listing
December 2018

Pregnancy and thrombosis: Adrenal vein thrombosis. A retrospective descriptive study of 14 cases.

Eur J Obstet Gynecol Reprod Biol 2019 Feb 30;233:38-42. Epub 2018 Nov 30.

Obstetrics and Gynecology Department, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Lyon, France.

Objectives: Adrenal vein thrombosis during pregnancy is a rare thromboembolic event but is not exceptional. The objective of this study was to described the symptoms, diagnosis, treatment and follow-up of patients with this condition.

Study Design: This was a retrospective descriptive study of 14 cases (13 patients, one recurrence) that occurred in the three university maternity hospitals in Lyon (France) from 2008 to 2016. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2018.10.055DOI Listing
February 2019
3 Reads

Using misoprostol to treat postpartum hemorrhage in home deliveries attended by traditional birth attendants.

Int J Gynaecol Obstet 2019 Mar 24;144(3):290-296. Epub 2019 Jan 24.

Gynuity Health Projects, New York, NY, USA.

Objective: To explore the clinical and programmatic feasibility of using 800 μg of sublingual misoprostol to prevent and treat postpartum hemorrhage (PPH) during home delivery.

Methods: The present double-blind randomized controlled trial included women who underwent home deliveries in Chitral district, Khyber Pakhtunkhwa province, Pakistan, after presenting at healthcare facilities during the third trimester of pregnancy between May 28, 2012, and November 27, 2014. Participants were randomized in a 1:1 ratio to receive either 800 μg of misoprostol or placebo sublingually if PPH was diagnosed, having previously received a prophylactic oral dose of 600 μg misoprostol. Read More

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http://doi.wiley.com/10.1002/ijgo.12756
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http://dx.doi.org/10.1002/ijgo.12756DOI Listing
March 2019
2 Reads

Heat-Stable Carbetocin to Prevent Postpartum Hemorrhage.

N Engl J Med 2018 12;379(24):2381

World Health Organization, Geneva, Switzerland

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http://dx.doi.org/10.1056/NEJMc1812692DOI Listing
December 2018

Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis.

Cochrane Database Syst Rev 2018 12 19;12:CD011689. Epub 2018 Dec 19.

Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, University of Birmingham, C/o Academic Unit, 3rd Floor, Birmingham Women's Hospital Foundation Trust, Mindelsohn Way, Birmingham, UK, B15 2TG.

Background: Postpartum haemorrhage (PPH) is the leading cause of maternal mortality worldwide. Prophylactic uterotonic agents can prevent PPH, and are routinely recommended. The current World Health Organization (WHO) recommendation for preventing PPH is 10 IU (international units) of intramuscular or intravenous oxytocin. Read More

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http://doi.wiley.com/10.1002/14651858.CD011689.pub3
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http://dx.doi.org/10.1002/14651858.CD011689.pub3DOI Listing
December 2018
12 Reads

Maternal anaemia and maternal, fetal, and neonatal outcomes in a prospective cohort study in India and Pakistan.

BJOG 2018 Dec 16. Epub 2018 Dec 16.

Thomas Jefferson University, Philadelphia, PA, USA.

Objective: To describe the association of maternal anaemia with maternal, fetal, and neonatal outcomes.

Design: Prospective cohort study.

Setting: Rural India and Pakistan. Read More

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http://dx.doi.org/10.1111/1471-0528.15585DOI Listing
December 2018
4 Reads
3.448 Impact Factor

Postpartum flare up of systemic lupus erythematosus: Pulmonary diffused alveolar hemorrhage.

Taiwan J Obstet Gynecol 2018 Dec;57(6):906-907

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.tjog.2018.10.027DOI Listing
December 2018

Clinical utility and limitations of FibCare® for the rapid measurement of fibrinogen concentrations: The first clinical experience.

Taiwan J Obstet Gynecol 2018 Dec;57(6):899-900

Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

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http://dx.doi.org/10.1016/j.tjog.2018.10.024DOI Listing
December 2018

Uterine fibroids in pregnancy: prevalence, clinical presentation, associated factors and outcomes at the Limbe and Buea Regional Hospitals, Cameroon: a cross-sectional study.

BMC Res Notes 2018 Dec 13;11(1):889. Epub 2018 Dec 13.

Faculty of Health Sciences, University of Buea, P.O.Box 63, Buea, Cameroon.

Objectives: Uterine fibroids are common among the black race and associated with adverse outcomes in pregnancy. The aim of this study was to determine the prevalence, clinical presentation and maternal and foetal outcomes of birth among pregnant women with leiomyoma in two secondary care hospitals in Limbe and Buea, Cameroon.

Results: The prevalence of fibroid in pregnancy was 16. Read More

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http://dx.doi.org/10.1186/s13104-018-4007-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293543PMC
December 2018
3 Reads

Continuous support during labour in childbirth: a Cross-Sectional study in a university teaching hospital in Shanghai, China.

BMC Pregnancy Childbirth 2018 Dec 6;18(1):480. Epub 2018 Dec 6.

The Hospital of Obstetrics & Gynaecology, Fudan University, Shanghai, China.

Background: Fear or anxiety could result in adverse consequences on the course of labour. To date, family members are still not permitted in the delivery rooms in the majority of hospitals in China, and continuous support from hospital professional staff is also limited. This study aimed to evaluate the benefits of continuous support by family members and hospital professional staff during labour in China. Read More

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http://dx.doi.org/10.1186/s12884-018-2119-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282363PMC
December 2018
2 Reads
2.190 Impact Factor

Magnitude, trends and causes of maternal mortality among reproductive aged women in Kersa health and demographic surveillance system, eastern Ethiopia.

BMC Womens Health 2018 Dec 5;18(1):198. Epub 2018 Dec 5.

Mothers and Babies Research Centre, Faculty of Health and Medicine, University of Newcastle, Newcastle, Australia.

Background: Despite efforts at curbing maternal morbidity and mortality, developing countries are still burdened with high rates of maternal morbidity and mortality. Ethiopia is not an exception and has one of the world's highest rates of maternal deaths. Reducing the huge burden of maternal mortality remains the single most serious challenge in Ethiopia. Read More

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https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s
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http://dx.doi.org/10.1186/s12905-018-0690-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282369PMC
December 2018
10 Reads

Medical management of postpartum hemorrhage: An update.

Semin Perinatol 2018 Nov 14. Epub 2018 Nov 14.

Department of Anesthesiology, The University of Texas Medical Branch at Galveston, 301 University Blvd., Galveston, TX 77555-0587, United States.

Obstetrical hemorrhage is the most common cause of maternal mortality worldwide. Together with adequate surgical control and judicious transfusion of blood products, the use of pharmacological agents (e.g. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01460005183012
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http://dx.doi.org/10.1053/j.semperi.2018.11.005DOI Listing
November 2018
6 Reads

Distribution of postpartum blood loss: modeling, estimation and application to clinical trials.

Reprod Health 2018 Dec 4;15(1):199. Epub 2018 Dec 4.

Department of Reproductive Health and Research, World Health Organization, UNDP/UNFPA/ UNICEF/WHO/World Bank Special programme of research, development and research training in human reproduction (HRP), Geneva, Switzerland.

Background: The loss of large amounts of blood postpartum can lead to severe maternal morbidity and mortality. Understanding the nature of postpartum blood loss distribution is critical for the development of efficient analysis techniques when comparing treatments to prevent this event. When blood loss is measured, resulting in a continuous volume measure, often this variable is categorized in classes, and reduced to an indicator of volume greater than a cutoff point. Read More

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http://dx.doi.org/10.1186/s12978-018-0641-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280488PMC
December 2018
2 Reads

Massive hemorrhage protocol activation in obstetrics: a 5-year quality performance review.

Int J Obstet Anesth 2018 Nov 3. Epub 2018 Nov 3.

Department of Transfusion Medicine.

Background: A structured approach to hemorrhagic emergencies in obstetrics has gained popularity with the implementation of massive hemorrhage protocols. The trauma literature suggests that routine quality reviews should be in place to improve patient outcomes. The aim of this study was to develop quality indicators and assess compliance by the clinical team. Read More

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http://dx.doi.org/10.1016/j.ijoa.2018.10.004DOI Listing
November 2018
1 Read

Intracervical Foley catheter balloon versus dinoprostone insert for induction cervical ripening: A systematic review and meta-analysis of randomized controlled trials.

Medicine (Baltimore) 2018 Nov;97(48):e13251

Clinical Medicine College, Soochow University, Suzhou Jiangsu, China.

Background: Successful labor induction depends on the cervical status at the time of induction. Currently, both a Foley catheter and a dinoprostone insert are used for effective cervical ripening. This study compared the efficacy and safety of the intracervical Foley catheter and dinoprostone insert for cervical ripening to achieve successful labor induction. Read More

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http://dx.doi.org/10.1097/MD.0000000000013251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283136PMC
November 2018
3 Reads

Postpartum anticoagulation in women with mechanical heart valves.

Int J Womens Health 2018 25;10:663-670. Epub 2018 Oct 25.

Department of Obstetrics, Gynecology and Reproductive Sciences, Section of Maternal-Fetal Medicine, Yale University School of Medicine, New Haven, CT, USA,

Background: Women with mechanical heart valves (MHV) requiring anticoagulation (AC) are at high risk for hemorrhagic complications. Despite guidelines to manage antenatal and peripartum AC, there are few evidence-based recommendations to guide the initiation of postpartum AC. We reviewed our institutional experience of pregnant women with MHV to lay the groundwork for recommendations of immediate postpartum AC therapy. Read More

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https://www.dovepress.com/postpartum-anticoagulation-in-wome
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http://dx.doi.org/10.2147/IJWH.S177547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207249PMC
October 2018
8 Reads

Comparison between Carbetocin and Oxytocin in Active Management of 3rd Stage of Labour in Preventing Post Partum Hemorrhage.

Mymensingh Med J 2018 Oct;27(4):793-797

Dr Parul Akhter, Assistant Professor, Department of Gynae & Obs, Sir Salimullah Medical College, Mitford, Dhaka, Bangladesh.

The third stage of labour is considered to be the most critical part of child birth due to the risk of post partum haemorrhage (PPH). To compare the effectiveness of carbetocin and oxytocin in the management of 3rd stage of labour in preventing post partum hemorrhage, this experimental clinical trial was conducted in the Department of Obstetrics and Gynecology, Sir Salimulla Medical College Hospital, Dhaka, Bangladesh from January 2015 to June 2016. Three hundred women undergoing normal vaginal delivery were consecutively enrolled. Read More

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October 2018
4 Reads

A Randomized Controlled Trial of Immediate versus Delayed Umbilical Cord Clamping in Multiple-Birth Infants Born Preterm.

Neonatology 2018 Nov 27;115(2):156-163. Epub 2018 Nov 27.

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Background: Delayed cord clamping (DCC) improves placental transfusion and increases blood volume in preterm infants when compared with immediate cord clamping (ICC). However, evidence to support DCC in multiple-birth preterm infants is still lacking.

Objective: To compare the outcomes of ICC versus DCC in preterm infants of multiple births. Read More

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https://www.karger.com/Article/FullText/494132
Publisher Site
http://dx.doi.org/10.1159/000494132DOI Listing
November 2018
10 Reads

Menstrual and reproductive outcomes after use of balloon tamponade for severe postpartum hemorrhage.

BMC Pregnancy Childbirth 2018 Nov 21;18(1):451. Epub 2018 Nov 21.

Department of Obstetrics and Gynaecology, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong.

Background: The use of intrauterine balloon tamponade to manage postpartum hemorrhage is increasing. However, there is lack of studies on the menstrual and reproductive outcomes after such treatment. The purpose of this study is to explore the menstrual and reproductive outcomes for patients who had been managed by intrauterine balloon tamponade for severe postpartum hemorrhage in her index pregnancy. Read More

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http://dx.doi.org/10.1186/s12884-018-2085-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249747PMC
November 2018
1 Read

Increased incidence of obstetric complications in women carrying mitochondrial DNA mutations: a retrospective cohort study in a single tertiary centre.

BJOG 2018 Nov 20. Epub 2018 Nov 20.

Department of Obstetrics, Assistance Publique - Hôpitaux de Paris (AP-HP), Paris, France.

Objective: To investigate the obstetric outcome of women carriers of the oxidative phosphorylation (OXPHOS) disorder mutation.

Design: A retrospective cohort study in a single tertiary centre.

Setting: A review of the obstetric history of women referred for prenatal screening of a mitochondrial disorder was performed. Read More

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http://dx.doi.org/10.1111/1471-0528.15515DOI Listing
November 2018
7 Reads

Aplastic anaemia in pregnancy - a single centre, North American series.

Br J Haematol 2019 Feb 20;184(3):436-439. Epub 2018 Nov 20.

Departments of Medicine, Pathology and Laboratory Medicine, University of Toronto, Toronto, Ontario, Canada.

Aplastic anaemia (AA) is infrequently observed in pregnancy. We describe 19 pregnancies in 9 women at a tertiary care centre over a period of 30 years. Spontaneous resolution of AA did not occur postpartum in the five pregnancies where AA was first diagnosed in pregnancy. Read More

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http://dx.doi.org/10.1111/bjh.15654DOI Listing
February 2019
8 Reads

Use of the shock index to predict maternal outcomes in women referred for postpartum hemorrhage.

Int J Gynaecol Obstet 2019 Feb 10;144(2):221-224. Epub 2018 Dec 10.

Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, South Korea.

Objective: To evaluate the clinical significance of various vital signs in women referred for postpartum hemorrhage (PPH).

Methods: This retrospective study included patients with primary PPH who were referred to Korea University Medical Center, Ansan, between January 1, 2004, and December 31, 2016. We analyzed data for systolic and diastolic blood pressure, heart rate, and shock index (heart rate divided by systolic blood pressure) at time of arrival. Read More

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http://doi.wiley.com/10.1002/ijgo.12714
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http://dx.doi.org/10.1002/ijgo.12714DOI Listing
February 2019
8 Reads

Assessing the effect of risk factors on rates of obstetric transfusion over time using two methodological approaches.

BMC Med Res Methodol 2018 Nov 16;18(1):139. Epub 2018 Nov 16.

Clinical and Population Perinatal Health Research, Kolling Institute, Northern Sydney Local Health District, St Leonards, NSW, Australia.

Background: While red blood cell transfusion rates have declined in most Australian medical specialties, obstetric transfusion rates have instead been increasing. Obstetric transfusions are mostly linked to postpartum haemorrhage, the rates of which have also increased over time. This study used two methodological approaches to investigate recent trends in obstetric transfusion in New South Wales (NSW) and the extent to which this was influenced by changing maternal and pregnancy characteristics. Read More

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https://bmcmedresmethodol.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s12874-018-0595-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240252PMC
November 2018
5 Reads

[Analysis of treatment with 167 critically ill pregnant women in intensive care unit].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2018 Oct;30(10):964-967

Department of Critical Care Medicine, the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, Guizhou, China. Corresponding author: Wang Difen, Email:

Objective: To analyze the pathogenic factors, clinical features and treatment measures of critically ill pregnant women so as to provide experience for improving the success rate of treatment.

Methods: The clinical data of 167 cases of critically ill pregnant women who admitted to intensive care unit (ICU) of the Affiliated Hospital of Guizhou Medical University from January 2013 to December 2017 were collected, and the disease distribution of patients, the causes of postpartum hemorrhage, the treatment situation and the results. Patients were divided into obstetrical complications group, pregnancy complicated with basic diseases group and other complicated diseases group according to disease types, and the treatment status of each group was analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.2095-4352.2018.010.012DOI Listing
October 2018
2 Reads

[Correlation between shock index and diastolic blood pressure in patients with postpartum hemorrhage and early warning of postpartum hemorrhage risk: an analysis of numerous cases in 4 years].

Authors:
Dexue Zu Yi Zhuge

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2018 Oct;30(10):959-963

Department of Gynaecology and Obstetrics, Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, Zhejiang, China (Zu DX); Faculty of Medicine, Quzhou Technology College, Quzhou 324000, Zhejiang, China (Zhuge Y). Corresponding author: Zhuge Yi, Email:

Objective: To observe the changes of shock index (SI) and diastolic blood pressure (DBP) in postpartum hemorrhage patients, and the explore their relationship with postpartum hemorrhage and the clinical significance of early warning of hemorrhage risk.

Methods: 402 patients with postpartum hemorrhage (within 24 hours after delivery, the amount of bleeding in vaginal delivery ≥ 500 mL, and the amount of bleeding in caesarean delivery ≥ 1 000 mL) admitted to the obstetrics ward of Affiliated Hospital of Hangzhou Normal University from January 2014 to December 2017 were selected as the objective group and 416 without complications during delivery were selected as the control group in the same hospital at the same period. Clinical data in the two groups before and after childbirth was collected, including age, pregnancy week, 24-hour blood loss, and hemoglobin (Hb), whole blood cell parameters, heart rate (HR), systolic blood pressure (SBP), DBP, SI, blood urea nitrogen (BUN), serum creatinine (SCr) within 24 hours before and after delivery, and postpartum 24 hours and prenatal DBP difference (ΔDBP). Read More

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http://dx.doi.org/10.3760/cma.j.issn.2095-4352.2018.010.011DOI Listing
October 2018
6 Reads

Blood transfusion following intended vaginal birth after cesarean versus elective repeat cesarean section in women with a prior primary cesarean: A population-based record linkage study.

Acta Obstet Gynecol Scand 2018 Nov 15. Epub 2018 Nov 15.

Clinical and Population Perinatal Health Research, Kolling Institute, Northern Sydney Local Health District, St Leonards, NSW, Australia.

Introduction: There is a lack of evidence around the risk of transfusion following vaginal birth after cesarean (VBAC) compared with elective repeat cesarean section (ERCS); this is important for decision-making about birth options. The aim of this study was to determine transfusion rates and risk of transfusion following intended VBAC and ERCS.

Material And Methods: Women with a primary cesarean who had a subsequent birth at term (≥37 weeks) in New South Wales between 2000 and 2012, were identified from the New South Wales Perinatal Data Collection. Read More

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http://dx.doi.org/10.1111/aogs.13504DOI Listing
November 2018
6 Reads

Relationship between uterine smooth muscular CPI-17-signal pathway-mediated Ca sensitivity changes and uterine atony-induced postpartum haemorrhage.

J Obstet Gynaecol 2018 Nov 14:1-6. Epub 2018 Nov 14.

a Department of Gynaecology and Obstetrics, Fujian Provincial Maternity and Children's Hospital , Affiliated Hospital of Fujian Medical University , Fuzhou , PR China.

This study aimed to investigate the changes of protein kinase C (PKC)-potentiated phosphatase inhibitor of 17 ku (CPI-17) expression, PKC activity and Rho kinase activity in the maternal uterine smooth muscle (USM), and their roles in the occurrence of uterine atony-induced postpartum haemorrhage (UAI-PPH). Sixty primiparaes who had a caesarean section performed were divided into the case group (with UAI-PPH) and the control group (the uterine contraction was good, without the PPH). The USM-p-CPI-17 (Thr38) protein levels, the activities of PKC and Rho kinase in the case group and the control group were 0. Read More

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http://dx.doi.org/10.1080/01443615.2018.1504206DOI Listing
November 2018

Gestational surrogacy: results of 10 years of experience in the Netherlands.

Reprod Biomed Online 2018 Dec 26;37(6):725-731. Epub 2018 Oct 26.

Department of Obstetrics and Gynaecology, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.

Research Question: What are the reproductive and obstetric outcomes of the gestational surrogacy treatment in the Netherlands?

Design: This retrospective cohort study reports all data of gestational surrogacy treatment in the VU University Medical Centre over a period of 10 years. Data was collected from 60 intended parents and 63 gestational carriers, including reproductive and obstetric outcomes.

Results: All intended mothers had a medical indication for gestational surrogacy and used autologous oocytes, and semen of the intended father. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14726483183052
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http://dx.doi.org/10.1016/j.rbmo.2018.09.017DOI Listing
December 2018
6 Reads

Malpresentation in low- and middle-income countries: Associations with perinatal and maternal outcomes in the Global Network.

Acta Obstet Gynecol Scand 2018 Nov 10. Epub 2018 Nov 10.

Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.

Introduction: Uncertainty exists regarding the impact of malpresentation on pregnancy outcomes and the optimal mode of delivery in low- and middle-income countries. We sought to compare outcomes between cephalic and non-cephalic pregnancies.

Material And Methods: Using the NICHD Global Network's prospective, population-based registry of pregnancy outcomes from 2010 to 2016, we studied outcomes in 436 112 singleton pregnancies. Read More

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http://doi.wiley.com/10.1111/aogs.13502
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http://dx.doi.org/10.1111/aogs.13502DOI Listing
November 2018
10 Reads
1.990 Impact Factor

Maternal position in the second stage of labour for women with epidural anaesthesia.

Cochrane Database Syst Rev 2018 11 9;11:CD008070. Epub 2018 Nov 9.

Division of Child Health, Obstetrics and Gynaecology, School of Medicine, University of Nottingham, Nottingham City Hospital NHS Trust, Hucknall Road, Nottingham, Nottinghamshire, UK, NG5 1PB.

Background: Epidural analgesia in labour prolongs the second stage and increases instrumental delivery. It has been suggested that a more upright maternal position during all or part of the second stage may counteract these adverse effects. This is an update of a Cochrane Review published in 2017. Read More

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http://doi.wiley.com/10.1002/14651858.CD008070.pub4
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http://dx.doi.org/10.1002/14651858.CD008070.pub4DOI Listing
November 2018
10 Reads

Postpartum Superior Sagittal Sinus Thrombosis: A Case Report.

Korean J Neurotrauma 2018 Oct 31;14(2):146-149. Epub 2018 Oct 31.

Department of Neurosurgery, Hanyang University Guri Hospital, Guri, Korea.

Cerebral venous sinus thrombosis (CVST) is a rare disease. Early diagnosis and treatment are important, as CVST is potentially fatal. Pregnancy and puerperium are known risk factors for CVST. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.13004/kjnt.2018.
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http://dx.doi.org/10.13004/kjnt.2018.14.2.146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218358PMC
October 2018
18 Reads

Amniotic fluid embolism and spontaneous hepatic rupture during uncomplicated pregnancy: a case report and literature review.

J Matern Fetal Neonatal Med 2018 Nov 4:1-8. Epub 2018 Nov 4.

a Department of Forensic Science, School of Basic Medical Sciences , Central South University , Changsha , China.

Amniotic fluid embolism (AFE) and spontaneous hepatic rupture both are extremely rare complications of pregnancy that can be fatal to mother and/or child. AFE is characterized by a sudden collapse of the cardiovascular system, a change in mental status, and disseminated intravascular coagulation (DIC), occurring immediately during labor, delivery, or postpartum, caused by the inflow of amniotic components into the maternal circulation. Spontaneous hepatic rupture during pregnancy which is most often occurs alongside hypertensive disorders, eclampsia, or HELLP syndrome. Read More

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https://www.tandfonline.com/doi/full/10.1080/14767058.2018.1
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http://dx.doi.org/10.1080/14767058.2018.1526915DOI Listing
November 2018
11 Reads

Clinical guidelines-the challenges and opportunities: What we have learned from the case of misoprostol for postpartum hemorrhage.

Int J Gynaecol Obstet 2019 Jan 21;144(1):122-127. Epub 2018 Nov 21.

International Federation of Gynecology and Obstetrics (FIGO), London, UK.

Objective: To establish whether national guidelines for postpartum hemorrhage (PPH) reflect new scientific evidence on misoprostol, and determine the challenges faced in their implementation.

Methods: A web-based survey was sent by email to 130 national societies of obstetrics and gynecology (FIGO Member Associations) in 2016. The survey, composed of 18 questions, covered national guidelines on PPH with particular reference to misoprostol, the creation of national guidelines, and challenges to implementation. Read More

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http://doi.wiley.com/10.1002/ijgo.12704
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http://dx.doi.org/10.1002/ijgo.12704DOI Listing
January 2019
1 Read