9,267 results match your criteria Pregnancy Postpartum Hemorrhage


Clinical management of woman with bleeding disorders: A survey among European haemophilia treatment centres.

Haemophilia 2020 May 27. Epub 2020 May 27.

Department of Obstetrics and Gynaecology, Royal Free Foundation Hospital and Institute for Women's Health, University College London, London, UK.

Introduction: The impact of bleeding for women with bleeding disorders (WBD) is of increasing focus and importance. Despite this, optimal management strategies are unclear and knowledge gaps persist.

Aim: To examine practices and define research priorities on diagnosis and management of WBD in Europe. Read More

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http://dx.doi.org/10.1111/hae.14043DOI Listing

Comparison of two management options for labor induction following unsuccessful prostaglandin E2 ripening.

J Matern Fetal Neonatal Med 2020 May 24:1-5. Epub 2020 May 24.

Department of Obstetrics and Gynecology, Lenox Hill Hospital - Northwell Health, NY, NY, USA.

: We sought to compare the likelihood of a vaginal delivery (VD) using oxytocin, with and without a cervical ripening balloon, in nulliparous women who did not respond to initial ripening with prostaglandin E2 (PGE2).: We a performed a retrospective cohort study of nulliparous women with a singleton pregnancy at term who underwent cervical ripening with vaginal PGE2 between October 2015 and March 2019. Patients who did not respond to PGE2 ripening (bishop score (BS) of 6 or less with cervical dilation less than 3 cm) were stratified into two groups based on management: sequential ripening with a cervical ripening balloon in addition to oxytocin versus oxytocin alone. Read More

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http://dx.doi.org/10.1080/14767058.2020.1769594DOI Listing

A cluster-randomized, non-inferiority trial comparing use of misoprostol for universal prophylaxis vs. secondary prevention of postpartum hemorrhage among community level births in Egypt.

BMC Pregnancy Childbirth 2020 May 24;20(1):317. Epub 2020 May 24.

Gynuity Health Projects, 220 E 42nd St, Suite 710, New York, NY, USA.

Background: Previous community-based research shows that secondary prevention of postpartum hemorrhage (PPH) with misoprostol only given to women with above-average measured blood loss produces similar clinical outcomes compared to routine administration of misoprostol for prevention of PPH. Given the difficulty of routinely measuring blood loss for all deliveries, more operational models of secondary prevention are needed.

Methods: This cluster-randomized, non-inferiority trial included women giving birth with nurse-midwives at home or in Primary Health Units (PHUs) in rural Egypt. Read More

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http://dx.doi.org/10.1186/s12884-020-03008-5DOI Listing

Predictors of response after a second attempt of pharmacological labor induction: a retrospective study.

Arch Gynecol Obstet 2020 May 22. Epub 2020 May 22.

Obstetrics and Gynaecology Unit, Mauriziano Umberto I Hospital, Largo Turati 62, 10128, Turin, Italy.

Purpose: The aim of our study was to assess the outcomes of a prolonged induction carried out with a second sequential cycle of pharmacological stimulation after unsatisfactory response to a first attempt, and to highlight variables correlated with higher response rates.

Methods: A retrospective study was carried out on 157 women who underwent a two-step labor induction by vaginal prostaglandins followed by a second cycle of prostaglandins or intravenous oxytocin. Outcomes assessed were mode of delivery and maternal and neonatal morbidity. Read More

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http://dx.doi.org/10.1007/s00404-020-05578-3DOI Listing

Extracorporeal membrane oxygenation in pregnancy and the postpartum period: a systematic review of case reports.

Int J Obstet Anesth 2020 Apr 20. Epub 2020 Apr 20.

Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Cardiothoracic ICU, Department of Cardiac Thoracic and Vascular Surgery, National University Heart Centre, National University Hospital, Singapore. Electronic address:

The use of extracorporeal membrane oxygenation (ECMO) as salvage therapy for patients with severe cardiopulmonary failure has increased significantly in the past decade. However, the use of ECMO in pregnant and peripartum patients has received scant attention. We performed a systematic review of case reports in the literature, documenting indications and outcomes of ECMO in pregnancy and postpartum patients. Read More

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http://dx.doi.org/10.1016/j.ijoa.2020.04.004DOI Listing

Changes in Maternal Body Mass Index, Weight Gain and Outcome of Singleton Pregnancies from 2000 to 2015: A Population-based Retrospective Cohort Study in Hesse/Germany.

Geburtshilfe Frauenheilkd 2020 May 16;80(5):508-517. Epub 2020 Apr 16.

Clara Angela Foundation, Witten und Berlin, Germany.

Maternal obesity and excessive gestational weight gain (GWG) affect the outcomes of women and their offspring. Our aim was to evaluate population-based data from Germany. Data from 583 633/791 514 mother-child pairs obtained from the perinatal database in Hesse for the period from 2000 to 2015 were used after excluding incomplete or non-plausible datasets. Read More

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http://dx.doi.org/10.1055/a-1110-0859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234825PMC

Low Incidence of Maternal Near-Miss in Zhejiang, a Developed Chinese Province: A Cross-Sectional Study Using the WHO Approach.

Clin Epidemiol 2020 29;12:405-414. Epub 2020 Apr 29.

Department of Obstetrics and Gynaecology, Women's Hospital, Zhejiang University School of Medicine, People's Republic of China.

Background And Aim: Maternal near-miss (MNM) surveillance has been developed to identify severe complications in pregnancy since 2011 in China. However, very little is known about MNM in China. This study aims to explore the prevalence of MNM, the risk factors, and perinatal outcomes using the WHO near-miss approach in a developed Chinese province. Read More

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http://dx.doi.org/10.2147/CLEP.S243414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196796PMC

The effects of hands on and hands off/poised techniques on maternal outcomes: A systematic review and meta-analysis.

Midwifery 2020 May 1;87:102712. Epub 2020 May 1.

The Xibei Hospital for Women and Children, Xian 710061, China.

Background: Negative maternal outcomes such as perineal trauma and related perineal pain may cause both long-and short- term morbidities. Hands on and hands off/poised technique are two kinds of techniques to protect perineum during the second-stage of labor. Hands on technique has been the routine midwifery practice for a long time; nevertheless, the effects of hands on technique on protecting perineum has been doubted. Read More

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http://dx.doi.org/10.1016/j.midw.2020.102712DOI Listing

Histologic chorioamnionitis concomitant placental abruption and its effects on pregnancy outcome.

Placenta 2020 May 27;94:39-43. Epub 2020 Mar 27.

Department of Obstetrics & Gynecology, The Edith Wolfson Medical Center, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Holon, Israel.

Introduction: Two possible causative pathways have been suggested to participate in the development of placental abruption (PA), an acute inflammatory pathway and placental vascular derived, a chronic pathway. We aimed to study the impact of the inflammatory pathway on maternal and neonatal outcome.

Methods: The computerized medical files and placental reports of all pregnancies diagnosed with PA, between 11/2008-1/2019, at 24-42 weeks, were reviewed. Read More

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http://dx.doi.org/10.1016/j.placenta.2020.03.012DOI Listing

Carbetocin versus oxytocin for prevention of postpartum hemorrhage in hypertensive women undergoing elective cesarean section.

Hypertens Pregnancy 2020 May 18:1-7. Epub 2020 May 18.

Obstetrics and Gynecology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

: Assess the efficacy and safety of carbetocin, versus oxytocin in the prevention of postpartum hemorrhage in hypertensive women.: A randomized clinical trial.: Obstetrics and Gynecology Department of Suez Canal University Hospital. Read More

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http://dx.doi.org/10.1080/10641955.2020.1768268DOI Listing

Obstetric hemorrhage and risk of cardiovascular disease after three decades: A population-based cohort study.

BJOG 2020 May 16. Epub 2020 May 16.

Institut national de santé publique du Québec, Montreal, Quebec, Canada.

Objective: To investigate the association between obstetric hemorrhage and cardiovascular disease up to three decades after pregnancy.

Design: Population-based cohort study SETTING AND POPULATION: All women who delivered between 1989 and 2016 in Quebec, Canada.

Methods: Using hospital admissions data, 1,224,975 women were followed from their first delivery until March 2018. Read More

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http://dx.doi.org/10.1111/1471-0528.16321DOI Listing

An analysis of the maternal and infant outcomes in the delayed interval delivery of twins.

Taiwan J Obstet Gynecol 2020 May;59(3):361-365

Department of Obstetrics, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, PR China.

Objective: To investigate the treatment methods used for the delayed interval delivery of twins and to evaluate the maternal and infant outcomes.

Materials And Methods: The clinical data of 5 patients that underwent delayed interval delivery of twins at Fujian Maternal and Child Health Hospital from 2014 to 2018 were analyzed. The gestational ages at delivery, obstetrical management, the interval between deliveries, and the maternal and child outcomes were analyzed. Read More

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http://dx.doi.org/10.1016/j.tjog.2020.03.004DOI Listing

Early Pregnancy Screening for Women at High-Risk of GDM Results in Reduced Neonatal Morbidity and Similar Maternal Outcomes to Routine Screening.

J Pregnancy 2020 29;2020:9083264. Epub 2020 Jan 29.

Pregnancy Research Centre, Department of Maternal-Fetal Medicine, Royal Women's Hospital, Melbourne, VIC, Australia.

The Australasian Diabetes in Pregnancy Society recommends screening high-risk women for gestational diabetes mellitus (GDM) before 24 weeks gestation, under the assumption that an earlier diagnosis and opportunity to achieve normoglycemia will minimize adverse outcomes. However, little evidence exists for this recommendation. The study objective was to compare the pregnancy outcomes of high-risk women diagnosed with GDM before 24 weeks gestation and routinely diagnosed women after 24 weeks gestation. Read More

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http://dx.doi.org/10.1155/2020/9083264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204101PMC
January 2020

Risk factors for postpartum sepsis: a nested case-control study.

BMC Pregnancy Childbirth 2020 May 14;20(1):297. Epub 2020 May 14.

Global Women's Health, King's College, London, UK.

Background: The Majority (99%) of maternal deaths occur in low and middle-income countries. The three most important causes of maternal deaths in these regions are postpartum hemorrhage, pre-eclampsia and puerperal sepsis. There are several diagnostic criteria used to identify sepsis and one of the commonly used criteria is systematic inflammatory response syndrome (SIRS). Read More

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http://dx.doi.org/10.1186/s12884-020-02991-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227107PMC

Term cesarean breech delivery in the first pregnancy is associated with an increased risk for maternal and neonatal morbidity in the subsequent delivery: a national cohort study.

Arch Gynecol Obstet 2020 May 14. Epub 2020 May 14.

Department of Obstetrics and Gynecology, University Hospital Marburg, Marburg, Germany.

Purpose: To determine whether there is an association between term cesarean breech delivery in the first pregnancy and maternal and neonatal morbidities in the subsequent pregnancy and delivery.

Methods: We conducted a retrospective, nationwide Finnish population-based cohort study, including all deliveries from January 2000 to December 2017. We included all women with the first two consecutive singleton deliveries of which the first one was a breech delivery regardless of mode of delivery (n = 11,953), and constructed a data set in which the first two deliveries for these women were connected. Read More

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http://dx.doi.org/10.1007/s00404-020-05575-6DOI Listing

Pregnancy outcomes of patients with acute fatty liver of pregnancy: a case control study.

BMC Pregnancy Childbirth 2020 May 11;20(1):282. Epub 2020 May 11.

Department of Obstetrics and Gynecology, Beijing Youan Hospital, Capital Medical University, YouAn outer street No.8, Fengtai District, Beijing, 100006, China.

Background: Limited data exists regarding the pregnancy and infant outcomes of Acute Fatty Liver of Pregnancy (AFLP).

Methods: Retrospectively collected mothers with AFLP and mothers without AFLP in our center from 1/2008 to 6/2018. The primary assessment was to analyze and compare the frequency of negative maternal and fetal outcomes. Read More

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http://dx.doi.org/10.1186/s12884-020-02980-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216501PMC

Maternal and neonatal outcome of births planned in alongside midwifery units: a cohort study from a tertiary center in Germany.

BMC Pregnancy Childbirth 2020 May 6;20(1):267. Epub 2020 May 6.

Department of Obstetrics and Prenatal Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.

Background: For healthy women entering birth after uneventful pregnancy, midwife-led models of care have the potential to reduce interventions and increase the vaginal birth rate. In Germany, 98.4% of women are giving birth in consultant-led obstetric units. Read More

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http://dx.doi.org/10.1186/s12884-020-02962-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201515PMC

Incidence of postpartum haemorrhage defined by quantitative blood loss measurement: a national cohort.

BMC Pregnancy Childbirth 2020 May 6;20(1):271. Epub 2020 May 6.

Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.

Background: Visual estimation of blood loss following delivery often under-reports actual bleed volume. To improve accuracy, quantitative blood loss measurement was introduced for all births in the 12 hospitals providing maternity care in Wales. This intervention was incorporated into a quality improvement programme (Obstetric Bleeding Strategy for Wales, OBS Cymru). Read More

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http://dx.doi.org/10.1186/s12884-020-02971-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201938PMC

Surviving mothers and lost babies - burden of stillbirths and neonatal deaths among women with maternal near miss in eastern Ethiopia: a prospective cohort study.

J Glob Health 2020 Jun;10(1):01041310

Department of Obstetrics and Gynecology, Leiden University Medical Centre, Leiden, the Netherlands.

Background: Although maternal near miss (MNM) is often considered a 'great save' because the woman survived life-threatening complications, these complications may have resulted in loss of a child or severe neonatal morbidity. The objective of this study was to assess proportion of perinatal mortality (stillbirths and early neonatal deaths) in a cohort of women with MNM in eastern Ethiopia. In addition, we compared perinatal outcomes among women who fulfilled the World Health Organization (WHO) and the sub-Saharan African (SSA) MNM criteria. Read More

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http://dx.doi.org/10.7189/jogh.10.010413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182357PMC

Adverse effect of delayed pushing on postpartum blood loss in nulliparous women with epidural analgesia.

Int J Gynaecol Obstet 2020 May 4. Epub 2020 May 4.

Division of Obstetrics, University Hospital of Zurich, Zurich, Switzerland.

Objective: To test for an association between blood loss and time until pushing (TUP) after full cervical dilation in nulliparous women with epidural analgesia.

Methods: A prospective cohort study was performed at the University Hospital of Zurich between October 2015 and November 2016. Included were 228 nulliparous women with singleton pregnancy, planned vaginal delivery after 36 completed weeks of gestation, epidural analgesia, and guided active pushing. Read More

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http://dx.doi.org/10.1002/ijgo.13175DOI Listing

In vitro fertilization as an independent risk factor for placenta accreta spectrum: In vitro fertilization, an independent risk factor for placenta accreta.

Am J Obstet Gynecol 2020 Apr 30. Epub 2020 Apr 30.

Depatment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas. Electronic address:

Background: Placenta accreta spectrum (PAS) is well known in its association with catastrophic maternal outcomes. However, the pathophysiology rendering PAS is not well-defined. There has been emerging data that in vitro fertilization (IVF) may be a risk factor for placenta accreta. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.04.026DOI Listing

Analysis of vaginal delivery outcomes among pregnant women in Wuhan, China during the COVID-19 pandemic.

Int J Gynaecol Obstet 2020 Apr 29. Epub 2020 Apr 29.

Department of Gynecology and Obstetrics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.

Objective: To study vaginal delivery outcomes and neonatal prognosis and summarize the management of vaginal delivery during the COVID-19 pandemic.

Methods: A retrospective analysis of medical records and comparison of vaginal delivery outcomes between 10 pregnant women with clinical diagnosis of COVID-19 and 53 pregnant women without COVID-19 admitted to Zhongnan Hospital of Wuhan University between January 20 and March 2, 2020. Results of laboratory tests, imaging tests, and SARS-CoV-2 nucleic acid tests were also analyzed in neonates delivered by pregnant women with clinical diagnosis of COVID-19. Read More

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http://dx.doi.org/10.1002/ijgo.13188DOI Listing

Anatomic variations of the Uterine Artery. Review of the literature and their clinical significance.

Turk J Obstet Gynecol 2020 Mar 6;17(1):58-62. Epub 2020 Apr 6.

National and Kapodestrian University of Athens Medical School, Department of Anatomy and Surgical Anatomy, Athens, Greece.

Uterine arteries are the main vessels supplying blood to the uterus. Mainly, they originate from the anterior trunk of the internal iliac artery. Uterine arteries play an important role in pregnancy as well as transcatheter arterial embolization for postpartum hemorrhage and uterine fibroid management. Read More

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http://dx.doi.org/10.4274/tjod.galenos.2020.33427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171538PMC

Lower gestational age is associated with severe maternal morbidity of preterm cesarean delivery.

J Gynecol Obstet Hum Reprod 2020 Apr 23:101764. Epub 2020 Apr 23.

Department of Obstetrics and Gynecology, Nord Hospital, APHM, chemin des Bourrely, 13015, Marseille, France; EA3279, CEReSS, Health Service Research and Quality of Life Center, Aix-Marseille University, 13284, Marseille, France. Electronic address:

Objective: To evaluate whether gestational age was associated with the severe maternal morbidity (SMM) of preterm cesarean delivery between 22 and 34 weeks of gestation (weeks).

Material And Methods: We performed an observational retrospective cohort study in two tertiary university hospitals in 2018. We included all mothers of preterm infants born by caesarean delivery between 22 and 34 weeks, excluding mothers with multiple births greater than two, with pregnancy terminations or stillbirths, and who died unrelated to obstetrical causes. Read More

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http://dx.doi.org/10.1016/j.jogoh.2020.101764DOI Listing

Bimanual examination for clot evacuation: a retrospective cohort study of women with postpartum haemorrhage after vaginal delivery.

BMC Pregnancy Childbirth 2020 Apr 25;20(1):245. Epub 2020 Apr 25.

School of Women's and Children's Health, University of New South Wales, Randwick, NSW, Australia.

Background: Bimanual clot evacuation (BCE) is a simple clinical manoeuvre that may reduce need for surgical intervention in the management of severe postpartum haemorrhage (PPH). We sought to determine whether performing BCE in cases of severe PPH after vaginal birth reduces the need for surgical intervention.

Methods: A retrospective chart review of women who delivered vaginally with a severe PPH between January 1, 2011 and December 31, 2014 in a single tertiary women's hospital in Sydney, Australia was conducted. Read More

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http://dx.doi.org/10.1186/s12884-020-02916-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183670PMC

The Maternal Impact, Health Burden, and Postpartum Sequela in Triplet Pregnancies: A Retrospective Cohort.

Am J Perinatol 2020 Apr 24. Epub 2020 Apr 24.

Department of Obstetrics and Gynecology, TriHealth, Cincinnati, Ohio.

Objective:  The aim of the study is to describe the maternal health burden and perinatal outcomes in triplet pregnancies, and identify the maternal and pregnancy indicators associated with increased perinatal morbidity and mortality.

Study Design:  This is a retrospective cohort study of triplet pregnancies from 2007 to 2014. Maternal data were manually collected and assessed until 6 weeks postpartum, and neonatal data were assessed until hospital discharge or death. Read More

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http://dx.doi.org/10.1055/s-0040-1709489DOI Listing

Incidental myomectomy at time of vaginal delivery contributing to postpartum hemorrhage: A case report and review of the literature.

J Gynecol Obstet Hum Reprod 2020 Apr 20:101776. Epub 2020 Apr 20.

Department of Obstetrics and Gynecology, Division of Urogynecology, Walter Reed National Military Medical Center, Bethesda, MD, United States. Electronic address:

Background: Uterine leiomyoma are implicated in certain adverse pregnancy related outcomes such as postpartum hemorrhage. Large submucosal leiomyoma defined as greater than 5 cm, may have higher complication rates; however, high quality data is limited.

Case: A 44-year-old gravida 4 with history of two full-term vaginal deliveries presented at 40 and 2/7 weeks of gestation with premature rupture of membranes and delivered vaginally a viable female infant complicated by a postpartum hemorrhage due to uterine atony. Read More

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http://dx.doi.org/10.1016/j.jogoh.2020.101776DOI Listing

Increased Risk of Pre-eclampsia After Frozen-Thawed Embryo Transfer in Programming Cycles.

Front Med (Lausanne) 2020 8;7:104. Epub 2020 Apr 8.

Center for Reproductive Medicine, Shandong University, Jinan, China.

This study aims to investigate whether obstetric complications and perinatal outcomes after frozen embryo transfer (FET) in the programming cycles differ from that in the natural cycles. We conducted a retrospective cohort study collecting a total of 14,373 singletons born after frozen embryo transfer at the Center for Reproductive Medicine Affiliated to Shandong University from September 2013 to September 2018. The women were divided into two groups according to the regimens for endometrium preparation: either natural cycles ( = 10,211) or programming cycles ( = 4,162). Read More

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http://dx.doi.org/10.3389/fmed.2020.00104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156607PMC

Maternal obesity and intrapartum obstetric complications among pregnant women: Retrospective cohort analysis from medical birth registry in Northern Tanzania.

Obes Sci Pract 2020 Apr 13;6(2):171-180. Epub 2020 Jan 13.

Department of Community Health Institute of Public Health, Kilimanjaro Christian Medical College Moshi Tanzania.

Background: In the last decade, Tanzania has observed a dramatic increase in overweight and obesity among women of childbearing age, a demographic shift that has been associated with intrapartum obstetric complications in high-income countries. Similar increases in maternal morbidity including postpartum haemorrhage, hypertensive disorders of pregnancy, and rates of caesarean delivery have not yet documented in Tanzania. This analysis describes intrapartum obstetric complications associated with maternal obesity among pregnant women delivering at teaching hospital in Northern Tanzania. Read More

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http://dx.doi.org/10.1002/osp4.395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156821PMC

Maternal Mortality in Georgia: Incidence, Causes and Level of Underreporting: A National Reproductive Age Mortality Study 2014.

Int J Womens Health 2020 9;12:277-286. Epub 2020 Apr 9.

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

Introduction: Accurate data on maternal mortality are essential for assessing progress towards Sustainable Development Goals (SDG).The aim of the study was to determine the incidence and causes of maternal deaths in Georgia, then explore the potential for improvement of quality of maternal health care. The study's secondary aims were to identify the level of underreporting of maternal deaths in Georgian vital statistics over 1 year (2012) and to compare these results with previous data from 2006. Read More

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http://dx.doi.org/10.2147/IJWH.S227349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154943PMC

Predictors of perinatal death in the presence of missing data: A birth registry-based study in northern Tanzania.

PLoS One 2020 16;15(4):e0231636. Epub 2020 Apr 16.

School of Mathematics, Statistics & Computer Science, University of KwaZulu-Natal, Pietermaritzburg, South Africa.

Background: More than five million perinatal deaths occur each year globally. Despite efforts put forward during the millennium development goals era, perinatal deaths continue to increase relative to under-five deaths, especially in low- and middle-income countries. This study aimed to determine predictors of perinatal death in the presence of missing data using birth registry data from Kilimanjaro Christian Medical Center (KCMC), between 2000-2015. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231636PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161952PMC
April 2020
3.234 Impact Factor

Immunological Role of the Maternal Uterine Microbiota in Postpartum Hemorrhage.

Front Immunol 2020 31;11:504. Epub 2020 Mar 31.

Department of Gynecology and Obstetrics, Universidad ICESI, Cali, Colombia.

Recent metagenomics and microbiology studies have identified microorganisms that are typical of the fetoplacental unit. Considering this emerging evidence, the placenta, uterus, and the amniotic cavity are not sterile and not immune privileged. However, there is evidence for a beneficial interaction between active maternal immune system and the presence of commensal pathogens, which lead to an immune-tolerant state, thereby preventing fetal rejection. Read More

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http://dx.doi.org/10.3389/fimmu.2020.00504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137651PMC

Twin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort study.

BMC Pregnancy Childbirth 2020 Apr 15;20(1):222. Epub 2020 Apr 15.

Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, 566, Nonhyeon-ro, Gangnam-gu, Seoul, 135-081, Republic of Korea.

Background: Twin pregnancies with uterine fibroid(s) (UFs) may not be at increased risk for obstetric complications compared to those without UFs. However, there was no reported comparison study with obstetric outcomes and complications of twin pregnancy after myomectomy. We aimed to compare the pregnancy outcomes in twin pregnancies with or without uterine fibroid(s), and also compared in patients with previous myomectomy history in Korean women. Read More

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http://dx.doi.org/10.1186/s12884-020-02908-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161148PMC

Risk Factors for Neonatal/Maternal Morbidity and Mortality in African American Women with Placental Abruption.

Medicina (Kaunas) 2020 Apr 13;56(4). Epub 2020 Apr 13.

Department of Obstetrics and Gynecology, New York Health and Hospitals/Lincoln, Bronx, NY 10451, USA.

: Risk factors for neonatal/maternal morbidity and mortality in placental abruption have been incompletely studied in the current literature. Most of the research overlooked the African American population as mostly Caucasian populations are selected. We aimed to find which risk factor influence the neonatal and maternal outcome in cases of placental abruption occurring in African American pregnant women in an inner-city urban setting. Read More

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http://dx.doi.org/10.3390/medicina56040174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230772PMC

Effect of previous placenta previa on outcome of next pregnancy: a 10-year retrospective cohort study.

BMC Pregnancy Childbirth 2020 Apr 15;20(1):212. Epub 2020 Apr 15.

Department of Obstetrics and Gynecology, Guangzhou Medical Centre for Critical Pregnant Women, Key Laboratory for Major Obstetric Diseases of Guangdong Province, Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, 510150, China.

Background: To determine the effects of previous placenta previa on the maternal and neonatal outcomes of the next pregnancy.

Methods: This 10-year retrospective cohort study was conducted in the Department of Obstetrics and Gynecology, Third Affiliated Hospital of Guangzhou Medical University, between January 2009 and 2018. We retrospectively analyzed the effects of a previous singleton pregnancy in women with and without placenta previa on the outcomes of the subsequent pregnancy. Read More

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http://dx.doi.org/10.1186/s12884-020-02890-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161269PMC

Use of balloon tamponade in management of vaginal laceration and its possible complication of urinary stress incontinence: a case report.

BMC Pregnancy Childbirth 2020 Apr 15;20(1):214. Epub 2020 Apr 15.

Department of Obstetrics and Gynaecology, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong SAR.

Background: Postpartum haemorrhage from vaginal lacerations can occasionally be refractory to suturing and vaginal packing. Bakri uterine balloon has been widely adopted to stop uterine bleeding, but its use to stop bleeding in vaginal lacerations and its possible complications have seldom been reported.

Case Presentation: We report a patient who had vacuum delivery for fetal distress and subsequently had postpartum hemorrhage due to previous caesarean uterine scar rupture and multiple vaginal lacerations. Read More

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http://dx.doi.org/10.1186/s12884-020-02885-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161190PMC

The effectiveness of delivery ball use versus conventional nursing care during delivery of primiparae.

Pak J Med Sci 2020 Mar-Apr;36(3):550-554

Xuemei Li Department of Cardiovascular, Binzhou Shili Hospital, Binzhou, 256617, China.

Objective: To analyze the clinical effect of delivery ball and free position delivery nursing in primipara delivery.

Methods: Total 110 primipara who were admitted to the department of gynecology and obstetrics of our hospital from August 2017 to August 2018 were included in the study. They were randomly divided into an observation group and a control group, 55 each group. Read More

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http://dx.doi.org/10.12669/pjms.36.3.1440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150382PMC

Association of Primary Intracerebral Hemorrhage With Pregnancy and the Postpartum Period.

JAMA Netw Open 2020 Apr 1;3(4):e202769. Epub 2020 Apr 1.

Center for Outcomes Research, Houston Methodist Research Institute, Houston, Texas.

Importance: Intracerebral hemorrhage (ICH) during pregnancy and the postpartum period results in catastrophic maternal outcomes. There is a paucity of population-based estimates of pregnancy-related ICH risk, including risk during the extended postpartum period.

Objective: To evaluate ICH risk during pregnancy and an extended 24-week postpartum period in a population-level cohort and to determine fetal and maternal outcomes as well as demographic and comorbidity factors associated with ICH during pregnancy and post partum. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2020.2769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156993PMC

Teenage Pregnancy: Obstetric and Perinatal Outcome in a Tertiary Centre in Indonesia.

Obstet Gynecol Int 2020 26;2020:2787602. Epub 2020 Mar 26.

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Background: The incidence of teenage pregnancy is increasing in the world. It is a high-risk condition leading to adverse perinatal and obstetric outcomes. This study aims to evaluate the obstetric and perinatal outcomes of teenage pregnancy in Indonesian population. Read More

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http://dx.doi.org/10.1155/2020/2787602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136788PMC

Triangulating data sources for further learning from and about the MDSR in Ethiopia: a cross-sectional review of facility based maternal death data from EmONC assessment and MDSR system.

BMC Pregnancy Childbirth 2020 Apr 9;20(1):206. Epub 2020 Apr 9.

Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.

Background: Triangulating findings from MDSR with other sources can better inform maternal health programs. A national Emergency Obstetric and Newborn Care (EmONC) assessment and the Maternal Death Surveillance and Response (MDSR) system provided data to determine the coverage of MDSR implementation in health facilities, the leading causes and contributing factors to death, and the extent to which life-saving interventions were provided to deceased women.

Methods: This paper is based on triangulation of findings from a descriptive analysis of secondary data extracted from the 2016 EmONC assessment and the MDSR system databases. Read More

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http://dx.doi.org/10.1186/s12884-020-02899-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147013PMC
April 2020
2.190 Impact Factor

Pregnancy with Fontan circulation: A report of case series in Japan.

J Cardiol Cases 2020 Apr 30;21(4):161-163. Epub 2019 Dec 30.

Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Owing to new surgical procedures and medications, more women who have undergone the Fontan procedure reach childbearing ages. We report five cases of pregnancy with Fontan circulation. Case 1 had subchorionic hematoma (SCH), fetal growth restriction (FGR), and preterm labor (PTL). Read More

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http://dx.doi.org/10.1016/j.jccase.2019.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125375PMC

Maternal Obesity and Pregnancy Outcome: in Perspective of New Asian Indian Guidelines.

J Obstet Gynaecol India 2020 Apr 13;70(2):138-144. Epub 2020 Jan 13.

4Consultant, Department of OBGYN, Sri Gokulam Hospital, Salem, Tamilnadu India.

Background: Prevalence of obesity among women of reproductive age is increasing worldwide. As the prevalence increases among the women of reproductive age group, so it does among pregnant females. This study was conducted with the aim to assess obesity-related adverse maternal, neonatal and perinatal outcomes using new Asian Indian guidelines. Read More

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http://dx.doi.org/10.1007/s13224-019-01301-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109213PMC

Uterine balloon tamponade for the treatment of postpartum hemorrhage: a systematic review and meta-analysis-commentary.

Am J Obstet Gynecol 2020 04;222(4):291-292

Department of Obstetrics and Gynaecology, University of Bolivia, La Paz, Bolivia.

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http://dx.doi.org/10.1016/j.ajog.2020.01.018DOI Listing

Evaluation of mode of birth in pregnant women with heart disease.

Eur J Obstet Gynecol Reprod Biol 2020 May 6;248:150-155. Epub 2020 Mar 6.

Department of Obstetrics, Leiden University Medical Centre, the Netherlands.

Objective: Maternal heart disease (HD) complicates 1-4 % of pregnancies and is associated with adverse maternal and fetal outcomes. Although vaginal birth is generally recommended in the guidelines, cesarean section (CS) rates in women with HD are often high. Aim of the present study was to evaluate mode of birth and pregnancy outcomes in women with HD in a tertiary care hospital in the Netherlands. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2020.03.013DOI Listing

Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death.

Clin Appl Thromb Hemost 2020 Jan-Dec;26:1076029620912819

Nursing Department, Baoji Maternal and Child Health Hospital, Baoji, China.

Congenital fibrinogen disorders are a group of most frequent rare coagulation disorder, characterized by deficiency and/or defects in the fibrinogen molecule. Quantitative disorders include hypofibrinogenemia and afibrinogenemia. Due to their specific physiological characteristics, female patients tend to have congenital hypofibrinogenemia/afibrinogenemia, such as spontaneous recurrent abortion, menorrhagia, infertility, antepartum and postpartum hemorrhage, and so on. Read More

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http://dx.doi.org/10.1177/1076029620912819DOI Listing

Unintended pregnancy and maternal health complications: cross-sectional analysis of data from rural Uttar Pradesh, India.

BMC Pregnancy Childbirth 2020 Mar 30;20(1):188. Epub 2020 Mar 30.

Center on Gender Equity and Health, Division of Global Public Health, University of California, San Diego School of Medicine, La Jolla, CA, USA.

Background: This study aims to explore the potential association between unintended pregnancy and maternal health complications. Secondarily, we test whether antenatal care (ANC) and community health worker (CHW) visits moderate the observed association between unintended pregnancy and maternal health complications.

Methods: Cross sectional data were collected using a multistage sampling design to identify women who had a live birth in the last 12 months across 25 highest risk districts of Uttar Pradesh (N = 3659). Read More

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http://dx.doi.org/10.1186/s12884-020-2848-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106893PMC
March 2020
2.190 Impact Factor

Quality, availability and storage conditions of oxytocin and misoprostol in Malawi.

BMC Pregnancy Childbirth 2020 Mar 29;20(1):184. Epub 2020 Mar 29.

Pharmaceutical Institute, Eberhard Karls University Tuebingen, Tuebingen, Germany.

Background: Postpartum haemorrhage (PPH) is the leading cause of maternal mortality in low- and middle-income countries (LMICs). Oxytocin and misoprostol are used for the prevention and treatment of PPH. However, both medicines are chemically unstable and sensitive to environmental conditions. Read More

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http://dx.doi.org/10.1186/s12884-020-2810-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104524PMC

Effects of low-dose aspirin on the prevention of preeclampsia and pregnancy outcomes: A randomized controlled trial from Shanghai, China.

Eur J Obstet Gynecol Reprod Biol 2020 May 19;248:156-163. Epub 2020 Mar 19.

The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China; Shanghai Municipal Key Clinical Specialty, Shanghai, China. Electronic address:

Objectives: To evaluate the preventive effects of low-dose aspirin on the incidence of preeclampsia and pregnancy outcomes of women at high-risk for preeclampsia.

Study Design: This prospective randomized clinical trial was conducted at the Obstetrics Department of The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, China. It analyzed data from 1105 high-risk women who were divided into the control group (placebo group) and the aspirin group (including three subgroups: 25 mg, 50 mg and 75 mg). Read More

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http://dx.doi.org/10.1016/j.ejogrb.2020.03.038DOI Listing

Uterine Compression Sutures in Controlling Postpartum Haemorrhage: A Narrative Review.

Acta Med Port 2019 Oct 7. Epub 2019 Oct 7.

Departamento da Mulher e da Medicina Reprodutiva. Centro Materno Infantil do Norte. Centro Hospitalar Universitário do Porto. Porto. Unidade de Investigação e Formação. Centro Materno Infantil do Norte. Centro Hospitalar Universitário do Porto. Porto. Instituto de Investigação e Inovação em Saúde. Universidade do Porto. Porto. Portugal.

Introduction: Postpartum haemorrhage is still the main cause of maternal morbidity and mortality. Many treatments are available, but they may threaten fertility potential. As a uterine sparing procedure, we aimed to review uterine compression sutures in order to better understand when they should represent an appropriate option. Read More

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http://dx.doi.org/10.20344/amp.11987DOI Listing
October 2019

Patterns of prenatal antidepressant exposure and risk of preeclampsia and postpartum haemorrhage.

Paediatr Perinat Epidemiol 2020 Mar 24. Epub 2020 Mar 24.

Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.

Background: Antidepressant use later in pregnancy has been associated with preeclampsia and postpartum haemorrhage (PPH) in some studies.

Objectives: To evaluate the association between patterns of prenatal antidepressant dose across gestationand risk of precclampsia and PPH.

Methods: We utilised OptumLabs® Data Warehouse (2012-2016) administrative health care claims, identifying 226 932 singleton liveborn deliveries for this retrospective cohort study. Read More

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http://dx.doi.org/10.1111/ppe.12660DOI Listing