417,489 results match your criteria Pregnancy Diagnosis


[How I do…the diagnosis of a cervical pregnancy].

Gynecol Obstet Fertil Senol 2020 Jul 10. Epub 2020 Jul 10.

Service de Gynécologie-Obstétrique, Hôpital Femme-Mère-Enfant, HFME, Hospices civils de Lyon, 59 boulevard Pinel, 69000 Lyon, France.

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http://dx.doi.org/10.1016/j.gofs.2020.07.002DOI Listing

Phyllodes Tumor of the Breast during Pregnancy and Lactation; A Systematic Review.

Arch Iran Med 2020 Jul 1;23(7):488-497. Epub 2020 Jul 1.

First Department of Surgery, Faculty of Medicine, University of Yamanashi, Shimokato, Chuo, Yamanashi, Japan.

Background: Phyllodes tumor (PT) is a rare tumor of the breast, which may occur during pregnancy or lactation. Several studies have reviewed and discussed PT occurring in pregnancy, gathering up to 14 patients. We performed a thorough systematic review of the literature in an attempt to find all reported cases, and identify their common characteristics. Read More

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http://dx.doi.org/10.34172/aim.2020.46DOI Listing

Diabetes insipidus complicating apoplexy during pregnancy: the potential use of copeptin.

Intern Med J 2020 Jul;50(7):877-879

Adult Endocrinology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Pituitary apoplexy during pregnancy is rare but important to recognise, particularly in the hyperoestrogenaemic state when known lactotroph hyperplasia occurs. Untreated, the complication rates from pituitary adenomas depend upon the size of the adenoma before pregnancy. A history of thirst plus polydipsia during pregnancy raises suspicion for diabetes insipidus and a 24-h urine collection quantifying polyuria with an inappropriately low urine osmolality confirms the diagnosis. Read More

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http://dx.doi.org/10.1111/imj.14918DOI Listing

Manifest diabetes after gestational diabetes: a double-cohort, long-term follow-up in a Danish population.

Arch Gynecol Obstet 2020 Jul 12. Epub 2020 Jul 12.

Department of Gynecology and Obstetrics, Herning Hospital, Gl. Landevej 61, 7400, Herning, Denmark.

Purpose: The aim was to follow-up two cohorts of women with GDM to investigate the incidence and time of diagnosis of manifest diabetes mellitus (DM) postpartum and identify the risk factors for diabetes in our population.

Methods: A follow-up study on two independent cohorts having oral glucose tolerance test (OGTT) in 1991/1992 and 2011-2016: Cohort 1 consisted of 406 women including 54 with GDM and 352 with a non-GDM OGTT-test and cohort 2 had 433 women diagnosed with GDM. The first cohort had nearly 25 years of follow-up and gave information on magnitude, conversion rate and type of diabetes manifestation. Read More

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http://dx.doi.org/10.1007/s00404-020-05669-1DOI Listing

Screening for celiac disease among children with overweight and obesity: toward exploring celiac iceberg.

J Pediatr Endocrinol Metab 2020 Jul 13. Epub 2020 Jul 13.

Laboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.

Background The coexistence of celiac disease (CD) and obesity/overweight is not unusual. Objective We investigate the prevalence and clinical presentation of CD, detected by screening, among children with excessive weight gain. Methods We enrolled 200 children referred for overweight/obesity to our outpatient clinic. Read More

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http://dx.doi.org/10.1515/jpem-2020-0076DOI Listing

Current use and performance of the different fetal growth charts in the Italian population.

Eur J Obstet Gynecol Reprod Biol 2020 Jun 29;252:323-329. Epub 2020 Jun 29.

Department of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Via Gramsci 14, 43125 Parma, Italy. Electronic address:

Objectives: The choice of growth charts impacts on screening, diagnosis and clinical management of fetal growth abnormalities. The objectives of the study were to evaluate: 1) the clinical practice at a national level among tertiary referral centers in the use of fetal biometric growth charts; and 2) the impact on fetal growth screening of existing national and international growth charts.

Study Design: A questionnaire was sent to 14 Italian tertiary referral centers to explore biometric reference growth charts used in clinical practice. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2020.06.059DOI Listing

[At-risk drinking screening by general practitioners: A survey of patients in primary care].

Rev Epidemiol Sante Publique 2020 Jul 8. Epub 2020 Jul 8.

Département Universitaire d'Enseignement et de Recherche en Médecine Générale, Faculté de santé, université Paris-Est-Créteil (UPEC), 94010 Créteil, France; Équipe CEpiA (Clinical Epidemiology and Ageing), INSERM, IMRB, université Paris-Est-Créteil (UPEC), 94000 Créteil, France.

Background: The screening of patients who are at-risk drinkers, which means exceeding the thresholds defined by health authorities or associated with a specific situation (taking psychotropic drugs, having an organic pathology, driving a vehicle, drinking during pregnancy), represents a major issue in primary care. Few studies have offered perspective from the patients' standpoint. The main purpose of this study was to describe general practitioners at-risk drinking screening from their patients point of view. Read More

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http://dx.doi.org/10.1016/j.respe.2020.06.003DOI Listing

Detection of paternal origin of fetal trisomy 18 in a pregnancy conceived by assisted reproductive technology and in vitro fertilization.

Taiwan J Obstet Gynecol 2020 Jul;59(4):607-609

Department of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan; Department of Bioengineering, Tatung University, Taipei, Taiwan.

Objective: We present detection of paternal origin of fetal trisomy 18 in a pregnancy conceived by assisted reproductive technology (ART) and in vitro fertilization (IVF).

Case Report: A 39-year-old woman underwent ART and IVF because of primary infertility. The woman was infertile because of myoma and endometriosis. Read More

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http://dx.doi.org/10.1016/j.tjog.2020.05.024DOI Listing

Prenatal diagnosis of mosaicism for trisomy 12 in a single colony at amniocentesis in a pregnancy with a favorable outcome.

Taiwan J Obstet Gynecol 2020 Jul;59(4):604-606

Department of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan; Department of Bioengineering, Tatung University, Taipei, Taiwan.

Objective: We present prenatal diagnosis of mosaicism for trisomy 12 in a single colony at amniocentesis with a favorable outcome.

Case Report: A 36-year-old woman underwent amniocentesis at 18 weeks of gestation because of advanced maternal age. Amniocentesis revealed a karyotype of 47,XY,+12[1]/46,XY[14]. Read More

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http://dx.doi.org/10.1016/j.tjog.2020.05.023DOI Listing

Prenatal diagnosis and molecular cytogenetic characterization of a chromosome 1q42.3-q44 deletion in a fetus associated with ventriculomegaly on prenatal ultrasound.

Taiwan J Obstet Gynecol 2020 Jul;59(4):598-603

Department of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan; Department of Bioengineering, Tatung University, Taipei, Taiwan.

Objective: We present prenatal diagnosis and molecular cytogenetic characterization of a chromosome 1q42.3-q44 deletion in a fetus associated with ventriculomegaly on prenatal ultrasound, and we discuss the genotype-phenotype correlation.

Case Report: A 36-year-old woman underwent amniocentesis at 17 weeks of gestation because of advanced maternal age. Read More

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http://dx.doi.org/10.1016/j.tjog.2020.05.022DOI Listing

Indigenization of the median of markers for Down syndrome screening based on statistical analysis of medical big data.

Taiwan J Obstet Gynecol 2020 Jul;59(4):556-564

Center of Reproductive Medicine & Center of Prenatal Diagnosis, First Hospital, Jilin University, Changchun 130021, China. Electronic address:

Objective: To indigenize the median of Down syndrome (DS) screening markers for first and second trimester, and compare the impact of the indigenized and built-in median data on the efficiency of DS screening.

Materials And Methods: Data derived from first and Second-trimester screening (FTS and STS) for DS, composed of selected pregnancies deemed to be normal, were examined in a retrospective study. Indigenization regression analysis was calculated by using five models to fit statistical the raw data. Read More

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http://dx.doi.org/10.1016/j.tjog.2020.05.015DOI Listing

Number of embryos transferred and diagnosis of preeclampsia.

Reprod Biol Endocrinol 2020 Jul 11;18(1):68. Epub 2020 Jul 11.

Centers for Disease Control and Prevention, Atlanta, GA, USA.

Background: Multiple births and first pregnancy are associated with higher preeclampsia risk. It is unknown if the transfer of multiple embryos or first embryo transfer with assisted reproductive technology (ART) is also associated with greater preeclampsia risk.

Methods: We performed a retrospective cohort study of IVF clinics and hospitals in Massachusetts. Read More

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http://dx.doi.org/10.1186/s12958-020-00627-7DOI Listing

High multiple mutations of Plasmodium falciparum-resistant genotypes to sulphadoxine-pyrimethamine in Lagos, Nigeria.

Infect Dis Poverty 2020 Jul 11;9(1):91. Epub 2020 Jul 11.

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Chinese Center for Tropical Diseases Research, WHO Collaborating Center for Tropical Diseases, National Centre for International Research on Tropical Diseases, Ministry of Science and Technology, Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai, 200025, People's Republic of China.

Background: Plasmodium falciparum-resistance to sulphadoxine-pyrimethamine (SP) has been largely reported among pregnant women. However, the profile of resistance markers to SP dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) in the general population are varied and not frequently monitored. Currently, SP is used as partner drug for artemisinin combination therapy (SP-artesunate) in some sub-Saharan African countries or as a prophylactic drug in intermittent preventive treatment of malaria during pregnancy and infants and in seasonal malaria chemoprevention (SMC). Read More

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http://dx.doi.org/10.1186/s40249-020-00712-4DOI Listing

Metformin and insulin treatment of gestational diabetes: effects on inflammatory markers and IGF-binding protein-1 - secondary analysis of a randomized controlled trial.

BMC Pregnancy Childbirth 2020 Jul 11;20(1):401. Epub 2020 Jul 11.

Department of Medicine, University of Turku, 20014, Turku, Finland.

Background: Gestational diabetes mellitus (GDM) is characterized by disturbed glucose metabolism and activation of low-grade inflammation. We studied whether metformin treatment has favorable or unfavorable effects on inflammatory markers and insulin-like growth factor-binding protein 1 (IGFBP-1) in GDM patients compared with insulin, and whether these markers associate with major maternal or fetal clinical outcomes.

Methods: This is a secondary analysis of a previous randomized controlled trial comparing metformin (n = 110) and insulin (n = 107) treatment of GDM. Read More

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http://dx.doi.org/10.1186/s12884-020-03077-6DOI Listing

Role of prenatal magnetic resonance imaging in fetuses with isolated agenesis of corpus callosum in the era of fetal neurosonography: a systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2020 Jul 11. Epub 2020 Jul 11.

Center for Fetal Care and High-risk Pregnancy, Department of Obstetrics and Gynecology, University Hospital of Chieti, Chieti, Italy.

Introduction: Corpus callosum agenesis (ACC) is frequently diagnosed during fetal life; its prognosis depends also on additional anomalies. The additional value of fetal magnetic resonance imaging (MRI) in fetuses with 'isolated' complete (cACC) and partial (pACC) agenesis of the corpus callosum on ultrasound is still debated.

Material And Methods: We performed a systematic literature review and meta-analysis including fetuses with a prenatal diagnosis of cACC and pACC without associated structural anomalies on ultrasound, undergoing fetal MRI. Read More

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http://dx.doi.org/10.1111/aogs.13958DOI Listing

Field trial on the post-insemination intrauterine treatment of dairy cows with mild endometritis with cephapirin.

Theriogenology 2020 Jun 29;156:20-26. Epub 2020 Jun 29.

Clinical Unit for Herd Health Management in Ruminants, University Clinic for Ruminants, Department of Farm Animals and Veterinary Public Health, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210, Vienna, Austria.

Cows in estrus but with signs of clinical endometritis (CE) are often not inseminated or undergo an intrauterine treatment after artificial insemination (AI). Decades ago, the so-called Aström method was described as intrauterine infusion of iodine-potassium solution 2-4 days after AI. Nowadays, it is common to use antibiotics instead of iodine solution and the treatment is performed only a few hours after AI. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2020.06.024DOI Listing

Postpartum screening for Type 2 Diabetes Mellitus in women with Gestational Diabetes: is it really performed?

Diabetes Res Clin Pract 2020 Jul 7:108309. Epub 2020 Jul 7.

Diabetes Center - University of Pisa.

Aims: This study evaluates the adherence to postpartum type 2 diabetes mellitus (T2DM) screening in women with previous gestational diabetes (GDM) and identifies elements associated with poor attendance.

Methods: We retrospectively collected data from 650 consecutive women with GDM between 2016-2018, who should had 75g-OGTT, 4-12 weeks after delivery. Impaired glucose regulation (IGR) was defined according with ADA criteria. Read More

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http://dx.doi.org/10.1016/j.diabres.2020.108309DOI Listing

Acute pyelonephritis during pregnancy: a systematic review of the aetiology, timing, and reported adverse perinatal risks during pregnancy.

J Obstet Gynaecol 2020 Aug 5;40(6):739-748. Epub 2019 Sep 5.

Department of Obstetrics and Gynecology, University of South Alabama, Mobile, Canada.

We performed a comprehensive systematic review of acute pyelonephritis in pregnancy using PubMed, SCOPUS, ClinicalTrials.gov, and Ovid from inception to April 2018. About 7796 references were screened for inclusion, and 52 references from 1908 to 2017 were included. Read More

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http://dx.doi.org/10.1080/01443615.2019.1647524DOI Listing

Three cases of lung cancer in pregnancy and literature review.

Ann Palliat Med 2020 Jul 9. Epub 2020 Jul 9.

Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Background: The incidence of tumors during pregnancy is 1ntscomprising 0.07-0.1% of all malignant tumors. Read More

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http://dx.doi.org/10.21037/apm-20-999DOI Listing

Type I interferon receptors and interferon-τ-stimulated genes in peripheral blood mononuclear cells and polymorphonuclear leucocytes during early pregnancy in beef heifers.

Reprod Fertil Dev 2020 Jul 10. Epub 2020 Jul 10.

This study characterised the expression of interferon (IFN)-τ-stimulated genes (ISGs) and Type I IFN receptors in circulating polymorphonuclear cells (PMNs) of beef heifers and compared it with expression in peripheral blood mononuclear cells (PBMCs) up to Day 20 of gestation. Nelore heifers (n=26) were subjected to fixed-time AI (FTAI) on Day 0. PMNs and PBMCs were isolated on Days 0, 10, 14, 16, 18 and 20 after FTAI. Read More

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http://dx.doi.org/10.1071/RD19430DOI Listing

Psychological experiences of women with pregnancy termination due to fetal anomalies: a qualitative study from the perspective of women, their spouses, and healthcare providers in Iran.

Reprod Health 2020 Jul 9;17(1):109. Epub 2020 Jul 9.

Department of Adult Health Nursing, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Pregnancy termination due to fetal anomalies has many psychological consequences for women. Providing appropriate and desirable care to this group of women and their families plays an important role in the process of coping with this crisis. The aim of the present study was to explore the psychological experiences of women with pregnancy termination due to fetal anomalies. Read More

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http://dx.doi.org/10.1186/s12978-020-00959-yDOI Listing

Maternal Outcomes of Ongoing Pregnancies Complicated by Fetal Life-Limiting Conditions.

Am J Perinatol 2020 Jul 9. Epub 2020 Jul 9.

Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, Wisconsin.

Objective:  This study aimed to examine maternal outcomes of ongoing pregnancies complicated by fetal life-limiting conditions.

Study Design:  This was a retrospective matched cohort study of women with a diagnosis of fetal life-limiting condition between 2010 and 2018 in a single academic center. Cases were matched to controls (women who had normal fetal anatomic survey) according to year of delivery, body mass index, and parity in a 1:4 ratio. Read More

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http://dx.doi.org/10.1055/s-0040-1713927DOI Listing

Abortion in women with Down syndrome.

J Intellect Disabil Res 2020 Jul 9. Epub 2020 Jul 9.

Department of Special Education, University of Fribourg, Fribourg, Switzerland.

Background: Nearly two-thirds of pregnancies in women with Down syndrome (DS) end in abortion. The aim of the present study was to determine if these high abortion rates might relate to specific characteristics of women with DS, their life situation and the course of pregnancy.

Methods: In a sample of 351 pregnancies in Switzerland (1998 to 2009), women with DS were compared with women with other forms of intellectual disability (ID) and women without ID, regarding the type of abortion, personal characteristics and pregnancy complications that might increase the probability of abortion. Read More

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http://dx.doi.org/10.1111/jir.12761DOI Listing

Thrombocytopaenia in pregnancy: the importance of differential diagnosis during the COVID-19 pandemic.

J Matern Fetal Neonatal Med 2020 Jul 8:1-3. Epub 2020 Jul 8.

Department of Gynaecology and Obstetrics and Operative Surgery, Cantonal Hospital of Fribourg (HFR), Fribourg, Switzerland.

Since the beginning of the COVID-19 pandemic, an optimal management of vulnerable patients, such as pregnant women, has been regarded as a challenge for healthcare professionals. Although thrombocytopaenia is considered a minor criterion for admission within an intensive care unit, a low platelet count has been observed in COVID-19 patients, including a pregnant woman, who developed severe pulmonary complications. Furthermore, thrombocytopaenia has been proposed as a potential biomarker in order to identify cases at high-risk complications. Read More

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http://dx.doi.org/10.1080/14767058.2020.1786527DOI Listing

Transvaginal Natural Orifice Transluminal Endoscopic Surgery for Tubal Stump Pregnancy.

J Minim Invasive Gynecol 2020 Jul 5. Epub 2020 Jul 5.

Department of Obstetrics and Gynecology, Ege University Faculty of Medicine, Izmir, Turkey (Drs Ozceltik, Yeniel, Atay and Itil).

Objective: To demonstrate a case of left tubal stump pregnancy successfully treated using our two-step technique for transvaginal natural orifice transluminal endoscopic surgery (vNOTES).

Design: Demonstration of the technique using surgical video footage.

Setting: A tertiary university hospital. Read More

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http://dx.doi.org/10.1016/j.jmig.2020.06.026DOI Listing

Pregnancy-Related Complications in Patients With Fibromuscular Dysplasia: A Report From the European/International Fibromuscular Dysplasia Registry.

Hypertension 2020 08 8;76(2):545-553. Epub 2020 Jul 8.

Division of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium (M.P., S.D.M., A. Pasquet, A. Persu).

Current literature suggests a higher risk of pregnancy-related complications in patients with renal fibromuscular dysplasia (FMD). The aim of our study was to assess the nature and prevalence of pregnancy-related complications in patients subsequently diagnosed with FMD. A call for participation was sent to centers contributing to the European/International FMD Registry. Read More

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.15349DOI Listing

Cesarean scar ectopic pregnancy: A cause of failed first trimester surgical termination of pregnancy (case report).

Authors:
Haitham A Torky

JBRA Assist Reprod 2020 Jul 8. Epub 2020 Jul 8.

Department of Obstetrics & Gynecology - October 6th University & As-Salam International Hospital, Cairo, Egypt.

Cesarean scar (ectopic) pregnancy is due to blastocyst implantation on a Caesarean scar. The current case presented by vaginal bleeding after a failed surgical termination of pregnancy. The ultrasound scan revealed a cesarean scar ectopic pregnancy managed by surgical removal. Read More

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http://dx.doi.org/10.5935/1518-0557.20200039DOI Listing

Parental experiences of uncertainty following an abnormal fetal anomaly scan: Insights using Han's taxonomy of uncertainty.

J Genet Couns 2020 Jul 7. Epub 2020 Jul 7.

North Thames Genomic Laboratory Hub, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.

For a number of prospective parents, uncertainty during pregnancy starts when an anomaly is found during a routine fetal anomaly scan. This may be followed by numerous tests to determine the etiology and nature of the anomaly. In this study, we aimed to understand how prospective parents perceive and manage uncertainty after being confronted with a structural anomaly during their routine ultrasound. Read More

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http://dx.doi.org/10.1002/jgc4.1311DOI Listing

Rupture of splenic artery aneurysm in pregnancy with double-rupture phenomenon: A case report.

Case Rep Womens Health 2020 Jul 3;27:e00230. Epub 2020 Jun 3.

Obstetrics & Gynecology, Geisinger Medical Center, 100 Academy Avenue, Danville, PA 17822, United States of America.

Background: Rupture of a splenic artery aneurysm (SAA) is a rare and often life-threatening complication of pregnancy. The reported incidence is 0.01% to 10. Read More

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http://dx.doi.org/10.1016/j.crwh.2020.e00230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327824PMC

Recurrent Idiopathic Sweet Syndrome - Case Report and Literature Review.

Curr Health Sci J 2020 Jan-Mar;46(1):90-98. Epub 2020 Mar 31.

Department of Pathology, Emergency County Hospital, Craiova, University of Medicine and Pharmacy of Craiova, Romania.

Introduction: Sweet syndrome (SS), also denominated as acute febrile neutrophilic dermatosis, is a rare disease characterized by the sudden onset of painful, erythematous, firm skin lesions (papules, plaques, and nodules) which show, upon histologic examination, the presence of a diffuse infiltrate of mature neutrophils. The cutaneous manifestation typically involves the face, neck, trunk, and upper limbs and is associated with fever, general malaise, arthralgia.

Case Report: A female patient, 60 years old, attended the Dermatology Clinic due to the appearance of violaceous erythematous-oedematous infiltrated plaques, located on the face, neck, upper limbs, trunk and knees. Read More

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http://dx.doi.org/10.12865/CHSJ.46.01.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323719PMC

The "scar" of a pandemic: cumulative incidence of COVID-19 during the first trimester of pregnancy.

J Med Virol 2020 Jul 7. Epub 2020 Jul 7.

Gynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, Italy.

Congenitally- or perinatally-acquired viral infections can be harmful to the fetus but data are limited about prevalence and outcomes of COVID-19 disease during the first trimester of pregnancy. We report epidemiologic data from a study investigating a cohort of women who became pregnant just before or during the COVID-19 pandemic. We recruited 138 consecutive pregnant women attending for first trimester screening (11-13 weeks of gestation) at Sant'Anna Hospital, Turin, Piedmont, Italy, during the plateau and the falling phase of the COVID-19 epidemic curve. Read More

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http://dx.doi.org/10.1002/jmv.26267DOI Listing

Retrospective Description of Pregnant Women Infected with Severe Acute Respiratory Syndrome Coronavirus 2, France.

Emerg Infect Dis 2020 Jul 6;26(9). Epub 2020 Jul 6.

Little data are available on the management of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We conducted a retrospective study of 100 pregnant women with SARS-CoV-2 infection in 4 obstetric units in the Paris metropolitan area of France during March 12-April 13, 2020. Among patients, 52 (52%) were hospitalized, 10 (10%) in intensive care units (ICUs). Read More

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http://dx.doi.org/10.3201/eid2609.202144DOI Listing

Multi-biomarker strategy for prediction of myocardial dysfunction and mortality in sepsis.

J Zhejiang Univ Sci B 2020 Jul;21(7):537-548

Intensive Care Unit, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.

Objective: The present study was to evaluate the feasibility of using the multi-biomarker strategy for the prediction of sepsis-induced myocardial dysfunction (SIMD) and mortality in septic patients.

Methods: Brain natriuretic peptide (BNP), cardiac troponin I (cTnI), and heart-type fatty acid-binding protein (h-FABP) in 147 septic patients were assayed within 6 h after admission. We also determined the plasma levels of myeloperoxidase (MPO) and pregnancy-associated plasma protein-A (PAPP-A). Read More

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http://dx.doi.org/10.1631/jzus.B2000049DOI Listing

Chromosome microarray analysis should be offered to all invasive prenatal diagnostic testing following a normal rapid aneuploidy test result.

Clin Genet 2020 Jul 6. Epub 2020 Jul 6.

Biochemistry and Molecular Genetics Department, Hospital Clinic of Barcelona, Barcelona, Spain.

Chromosomal microarray analysis (CMA) has now replaced karyotyping in the analysis of prenatal cases with a fetal structural anomaly, whereas in those pregnancies undergoing invasive prenatal diagnosis with a normal fetal ultrasound, conventional karyotyping is still performed. The aims of this study were to establish the diagnostic yield of CMA in prenatal diagnosis, and to provide new data that might contribute to reconsider current practices. We reviewed 2,905 prenatal samples with a normal rapid aneuploidy detection test referred for evaluation by CMA testing. Read More

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http://dx.doi.org/10.1111/cge.13810DOI Listing

Strategies for diagnosis of fetal right atrium dilation: based on fetal cardiac anatomy and hemodynamics.

BMC Med Imaging 2020 Jul 6;20(1):76. Epub 2020 Jul 6.

Department of Ultrasound, Shengjing Hospital of China Medical University, NO.36 Sanhao Street, Heping District, Shenyang, 110004, Liaoning Province, China.

Background: Fetal right atrium (RA) dilation is frequently detected in routine screenings while it remains a challenge to clarify the reasons. This study aimed to analyze the cardiac anatomy and hemodynamics of fetal RA dilation and the changes of hemodynamic indexes.

Methods: In the retrospective study, 420 fetuses with RA dilation were included, which were classified into the physiological group (n = 202), volume overload group (n = 142), and the pressure overload group (n = 76). Read More

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http://dx.doi.org/10.1186/s12880-020-00477-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339432PMC

Health Care Costs Associated to Type of Feeding in the First Year of Life.

Int J Environ Res Public Health 2020 Jun 30;17(13). Epub 2020 Jun 30.

Pediatrics Section, Hospital Universitario Marqués de Valdecilla, 39008 Santander, Spain.

Background: Breastfeeding is associated with lower risk of infectious diseases, leading to fewer hospital admissions and pediatrician consultations. It is cost saving for the health care system, however, it is not usually estimated from actual cohorts but via simulation studies.

Methods: A cohort of 970 children was followed-up for twelve months. Read More

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http://dx.doi.org/10.3390/ijerph17134719DOI Listing

Primary vaginal Ewing sarcoma with uterine fibroid: A case report.

Medicine (Baltimore) 2020 Jul;99(27):e20859

Department of Ultrasound.

Rationale: Extra osseous Ewing sarcoma (ES), an uncommon malignant neoplasm, accounts for about 15% of Ewing sarcoma, which mainly affects paravertebral region, lower extremity, chest wall, retroperitoneum, pelvis, and hip. Here is a 54-year-old woman of primary vaginal Ewing sarcoma with uterine fibroid, which has been fewly known or reported.

Patient Concerns: The patient was admitted to our hospital because of vaginal pain. Read More

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http://dx.doi.org/10.1097/MD.0000000000020859DOI Listing

Perinatal Peril: Diagnosis of HIV in a Newborn.

Clin Chem 2020 Jul;66(7):878-881

Department of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1093/clinchem/hvaa052DOI Listing

Prenatal screening diagnosis and management in the era of coronavirus: the Sardinian experience.

J Perinat Med 2020 Jul 7. Epub 2020 Jul 7.

Department of Obstetrics and Gynecology, Prenatal and Preimplantation Genetic Diagnosis, Fetal Therapy, Microcitemico Pediatric Hospital "Antonio Cao", Cagliari, Sardinia, Italy.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new coronavirus, was first identified in December 2019 in Wuhan, China and spread rapidly, affecting many other countries. The disease is now referred to as coronavirus disease 2019 (COVID-19).The Italian government declared a state of emergency on 31st January 2020 and on 11th March World Health Organization (WHO) officially declared the COVID-19 outbreak a global pandemic. Read More

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http://dx.doi.org/10.1515/jpm-2020-0208DOI Listing

[The role of secretory immunoglobulin E in the differential diagnosis of rhinitis during pregnancy].

Vestn Otorinolaringol 2020 ;85(3):52-56

Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia.

Objective: To evaluate the role of secretory immunoglobulin E in the differential diagnosis of rhinitis in pregnant women.

Material And Methods: The study involved 97 pregnant women with rhinitis symptoms and 23 healthy pregnant women without rhinitis symptoms. The first group of the study included 37 pregnant women with previously confirmed (anamnestically and immunologically) allergic rhinitis (AR), the 2nd group of the study included 30 pregnant women with suspected beginning of the AR, the 3rd group of the study was 30 women with pregnant women's rhinitis, diagnosed on the base of follow-up study. Read More

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http://dx.doi.org/10.17116/otorino20208503152DOI Listing
January 2020

Thrombotic microangiopathy, DIC-syndrome and COVID-19: link with pregnancy prothrombotic state.

J Matern Fetal Neonatal Med 2020 Jul 6:1-9. Epub 2020 Jul 6.

Obstetrics and Gynecology, The First I.M. Sechenov Moscow State Medical University, (Sechenov University), Moscow, Russia.

For last months, humanity has faced a formidable unknown enemy, which is presented as a new coronavirus infection. Despite the fact that the causative agents of new diseases appear at a certain frequency and that the virus SARS-CoV-2 has certain common properties with its predecessors, at the moment we are dealing with a new unknown pathogenesis of the development of severe complications in patients with risk factors. A final understanding of pathological process mechanisms is the goal of the scientific community. Read More

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http://dx.doi.org/10.1080/14767058.2020.1786811DOI Listing

Comparison of different methods of patient education on preeclampsia: a randomized controlled trial.

J Matern Fetal Neonatal Med 2020 Jul 6:1-5. Epub 2020 Jul 6.

Department of Maternal-Fetal Medicine, Geisinger, Danville, PA, USA.

Background: Preeclampsia is a life-threatening condition unique to pregnancy that contributes to maternal mortality worldwide. Delays in diagnosis and treatment are contributing factors for most maternal deaths from preeclampsia. Patients who are educated and knowledgeable regarding this disease process may present earlier for care. Read More

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http://dx.doi.org/10.1080/14767058.2020.1786524DOI Listing

Successful pregnancy in women with inferior vena cava stenosis - case report and discussion.

Ginekol Pol 2020 ;91(6):331-333

1st Department of Obstetrics and Gynecology, Centre of Postgraduate Medical Education, Warsaw, Poland.

Objectives: Inferior vena cava syndrome (IVCS) is a heterogenous group of symptoms resulting in obstruction of the main vein inflow . Common reasons are thrombotic changes and tumors. Incidence of inferior vena cava (IVC) anomalies is 0. Read More

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http://dx.doi.org/10.5603/GP.a2020.0052DOI Listing
January 2020

Non‑invasive prenatal diagnosis of thalassemia through multiplex PCR, target capture and next‑generation sequencing.

Mol Med Rep 2020 Aug 15;22(2):1547-1557. Epub 2020 Jun 15.

nstitute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.

Prenatal clinical detection of thalassemia involves gap‑PCR and reverse dot blot (RDB) analysis of fetal DNA acquired through invasive methods. The present study aimed to develop a non‑invasive prenatal diagnostic method for thalassemia based on next‑generation sequencing (NGS). A total of eight families with proband children with thalassemia were recruited for the study during a subsequent pregnancy. Read More

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http://dx.doi.org/10.3892/mmr.2020.11234DOI Listing

Early Prediction of Corpus Luteum Functionality Using an Imaging Software.

Front Vet Sci 2020 18;7:299. Epub 2020 Jun 18.

Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.

The present study aimed to assess the applicability of luteal blood flow data acquired through the use of color Doppler ultrasonography and a post-processing analysis tool (ImageJ) for predicting pregnancy in buffaloes (). The experiment was carried out on 59 multiparous Italian Mediterranean buffaloes that underwent synchronization of estrus and fixed-time artificial insemination (TAI). Corpus luteum features (size: CLS and blood flow: BFA) were taken from Day 5 to 10 after TAI and retrospectively measured with ImageJ. Read More

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http://dx.doi.org/10.3389/fvets.2020.00299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314946PMC

Partial trisomy 4q and monosomy 5p inherited from a maternal translocationt(4;5)(q33; p15) in three adverse pregnancies.

Mol Cytogenet 2020 30;13:26. Epub 2020 Jun 30.

Department of Prenatal Diagnosis Medical Center of Xuzhou Central Hospital, Xuzhou Clinical Schools of Xuzhou Medical University and Nanjing Medical University, 199 South Jiefang Road, Xuzhou, 221009 Jiangsu China.

Background: Carriers of balanced reciprocal chromosomal translocations are at known reproductive risk for offspring with unbalanced genotypes and resultantly abnormal phenotypes. Once fertilization of a balanced translocation gamete with a normal gamete, the partial monosomy or partial trisomy embryo will undergo abortion, fetal arrest or fetal malformations. We reported a woman with chromosomal balanced translocation who had two adverse pregnancies. Read More

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http://dx.doi.org/10.1186/s13039-020-00492-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329393PMC
June 2020
2.662 Impact Factor

Breast cancer during pregnancy: matched study of diagnostic approach, tumor characteristics, and prognostic factors.

Tumori 2020 Jul 6:300891620925158. Epub 2020 Jul 6.

Hospital Universitari Son Espases, Palma, Illes Balears, Spain.

Introduction: Breast cancer is one of the most frequently occurring cancers during pregnancy and its incidence is increasing. Many studies have shown poor outcomes, the causes of which remain unclear.

Objectives: To analyze radiologic characteristics, histology, and prognosis factors of breast cancer during pregnancy. Read More

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http://dx.doi.org/10.1177/0300891620925158DOI Listing