449,173 results match your criteria Pregnancy Diagnosis

Spinal haemangioma with cauda equina syndrome in pregnancy.

BMJ Case Rep 2022 Jun 27;15(6). Epub 2022 Jun 27.

Department of Neurosciences, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.

The true incidence of haemangiomas, which are the most common benign tumours in the spine, is not known as they are most often asymptomatic and are detected at autopsy. It can become symptomatic due to the haemodynamic and hormonal changes in pregnancy which cause sudden expansion of the lesion. In this paper, we present a case of a woman in her 30s, primigravida at 31 weeks' gestation with acute urinary retention and neurological features suggestive of cauda equina syndrome. Read More

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Next-Generation Sequencing analysis discloses genes implicated in equine endometrosis that may lead to tumorigenesis.

Theriogenology 2022 Jun 20;189:158-166. Epub 2022 Jun 20.

Department of Animal Anatomy and Preclinical Sciences, University Centre of Veterinary Medicine JU-UA, University of Agriculture in Krakow, Mickiewicza 24/28, 30-059, Krakow, Poland. Electronic address:

Endometrosis is a periglandular fibrosis associated with dysfunction of affected glandular epithelial cells that is the most common cause of reduced fertility in mares, although it is not fully understood. The etiology of the disease is still partially unknown. This study focuses on understanding the genetic mechanisms potentially underlying endometrosis in mares using the Next Generation Sequencing (NGS) technique. Read More

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Neuropilin-1 is uniquely expressed on small syncytiotrophoblast extracellular vesicles but not on medium/large vesicles from preeclampsia and normal placentae.

Biochem Biophys Res Commun 2022 Jun 21;619:151-158. Epub 2022 Jun 21.

Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, United Kingdom. Electronic address:

Preeclampsia (PE) is a multisystem progressive hypertensive disorder unique to human pregnancy. The placenta is fundamental to its pathogenesis and releases placental factors as well as extracellular vesicles (small and medium/large syncytiotrophoblast extracellular vesicles (STB-EVs)) as a response to syncytiotrophoblast stress such as tissue factor and plasminogen activator inhibitors 1. Neuropilin 1 (NRP-1) is an anti-angiogenic factor involved in development, angiogenesis, arteriogenesis, and vascular permeability. Read More

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Influence of body condition score and its change after parturition on pregnancy rates to fixed-timed artificial insemination in Bos indicus beef cows.

Anim Reprod Sci 2022 Jun 18;243:107028. Epub 2022 Jun 18.

School of Veterinary Medicine and Animal Science, Sao Paulo State University (UNESP), Botucatu 18168-000, Brazil. Electronic address:

This experiment evaluated pregnancy rates to fixed-time artificial insemination (FTAI) in Bos indicus beef cows according to their body condition score (BCS) at calving and subsequent change until 30 days after FTAI. Non-pregnant, suckling Nelore cows (n = 593 primiparous, 461 secundiparous, and 893 multiparous) were evaluated for BCS at calving and FTAI, and at 30 days after FTAI when cow pregnancy status was verified. Cow BCS at calving was subtracted from BCS recorded at pregnancy diagnosis, and cows classified as those that lost BCS (L), maintained BCS (M), or gained BCS (G) during this period. Read More

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Maternal serum perlecan and ischemia modified albumin levels as biomarkers of preeclampsia severity.

Egypt J Immunol 2022 Jul;29(3):64-79

Department of Physiology, Faculty of Medicine for Girls, Al- Azhar University, Cairo, Egypt.

Preeclampsia (PE) is a pregnancy disorder characterized by hypertension and end-organ damage. Reliable biochemical markers for diagnosis and prediction of PE severity can improve maternal health, and several of these markers have been suggested till now. The goal of our study was to evaluate maternal serum levels of Perlecan and Ischemia modified albumin (IMA) in PE patients, and to investigate their relationship with the severity. Read More

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Prenatal Diagnosis of Cleft and Craniofacial Conditions: An International Analysis of Practice Patterns.

J Craniofac Surg 2022 Jun 27. Epub 2022 Jun 27.

Division of Plastic and Reconstructive Surgery, Children's Hospital of Philadelphia, Philadelphia, PA.

Abstract: Prenatal diagnosis of congenital anomalies is associated with increased parental stress. Surgical prenatal counseling for parents expecting a child with an orofacial cleft has been shown to reduce parental anxiety through education and expectation setting. Despite the prevalence and significance of these conditions throughout the world, little is known of international counseling practices as they pertain to clefts and other craniofacial conditions, specifically regarding topics of counseling and discussions of ethical issues including interruption of pregnancy (IOP). Read More

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An unexplained fetal intracranial hemorrhage with extensive and multifocal hemorrhagic lesions: A case report.

Medicine (Baltimore) 2022 Jun 24;101(25):e29335. Epub 2022 Jun 24.

Department of Obstetrics and Gynaecology, West China Second University Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children of the Ministry of Education, Sichuan University, No.20, Section 3, Renmin Nan Lu, Chengdu, Sichuan Province, China.

Rationale: Fetal intracranial hemorrhage (ICH) is an extremely rare complication of pregnancy, with subsequent neurological sequelae or fetal death. The diagnosis of fetal ICH is primarily based on ultrasound or magnetic resonance imaging.

Patient Concerns: An asymptomatic woman at 31 weeks of gestation was referred for a detailed anomaly scan because routine fetal ultrasonography showed suspected fetal ICH. Read More

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Angiogenic biomarkers for the follow-up of singleton pregnancies with suspected preeclampsia.

Minerva Obstet Gynecol 2022 Jun 22. Epub 2022 Jun 22.

Department of Ginecology and Obstetrics. Hospital Universitario Lucus Augusti, Lugo, Spain.

Background: Preeclampsia is a hypertensive disorder of pregnancy and one of the leading causes of maternal and fetal morbidity and mortality worldwide. While the underlying cause of remains unknown, abnormal placentation in early stages of pregnancy is thought to be a main triggering event for the more severe and early-onset forms. A consequence of placental insufficiency is an imbalance of angiogenic factors in the maternal circulation. Read More

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Salivary cortisol reactivity in 6-month-old infants of mothers with severe psychiatric disorders: findings from the face-to-Face Still-Face paradigm.

Compr Psychoneuroendocrinol 2021 Aug 3;7:100078. Epub 2021 Aug 3.

Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC, University Medical Center Rotterdam, the Netherlands.

Background: Maternal psychopathology is associated with altered HPA axis functioning in offspring. Most studies have focused on mildly affected populations, but less is known about the effect of severe maternal psychopathology. In our explorative study we investigated in a heterogenic sample of mothers with severe and long-lasting psychiatric disorders, if a diagnosis of depression and severity of general maternal psychiatric symptomatology were associated with infant salivary cortisol reactivity to the Face-to-Face Still-Face (FFSF) paradigm at 6 months of age. Read More

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Ten Rules for the Management of Moderate and Severe Traumatic Brain Injury During Pregnancy: An Expert Viewpoint.

Front Neurol 2022 9;13:911460. Epub 2022 Jun 9.

Anesthesia and Intensive Care, Policlinico San Martino Hospital, IRCCS for Oncology and Neuroscience, Genova, Italy.

Moderate and severe traumatic brain injury (TBI) are major causes of disability and death. In addition, when TBI occurs during pregnancy, it can lead to miscarriage, premature birth, and maternal/fetal death, engendering clinical and ethical issues. Several recommendations have been proposed for the management of TBI patients; however, none of these have been specifically applied to pregnant women, which often have been excluded from major trials. Read More

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Evaluation of Antepartum Factors for Predicting the Risk of Emergency Cesarean Delivery in Pregnancies Complicated With Placenta Previa.

Ochsner J 2022 ;22(2):146-153

Department of Obstetrics and Gynecology, Health Sciences University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.

The optimal delivery timing for patients with placenta previa remains controversial in the literature. To reduce spontaneous vaginal bleeding rates, which occur increasingly with advancing gestational weeks, elective cesarean delivery is advocated between 36 and 37 weeks of gestation, but this clinical approach does not take into consideration numerous patient variables. Few papers identify the risk factors for emergency cesarean delivery in patients with placenta previa. Read More

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January 2022

Epidemiology and Clinical Features of Listeriosis in Gipuzkoa, Spain, 2010-2020.

Front Microbiol 2022 9;13:894334. Epub 2022 Jun 9.

Department of Preventive Medicine, University of the Basque Country (UPV/EHU), San Sebastián, Spain.

Background: Listeriosis continues to be one of the most important notifiable foodborne diseases. Nonetheless, in Spain, there are few data on the molecular epidemiology of infections in recent years.

Aim: To describe clinical features and the molecular epidemiology of human listeriosis over an 11-year period (2010-2020) in Gipuzkoa, Northern Spain. Read More

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Mesenteric venous thrombosis in a pregnant woman at first trimester gestation: a case report.

J Surg Case Rep 2022 Jun 21;2022(6):rjac294. Epub 2022 Jun 21.

General and Digestive Surgery Service, Hospital Nossa Senhora das Graças, Curitiba, Brazil.

Mesenteric vein thrombosis (MVT) in a pregnant patient is a rare condition that seems to be associated with the pregnancy pró-thrombotic state. This can lead to severe circumstances such as intestinal hemorrhagic ischemia, sepsis, abortion and death. Abdominal assessment is challenging due to the anatomical and physiological changes during pregnancy. Read More

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Imaging Findings in Dogs and Cats With Presumptive Sclerosing Encapsulating Peritonitis.

Front Vet Sci 2022 9;9:891492. Epub 2022 Jun 9.

Département des Animaux de Compagnie, Clinique Vétérinaire Universitaire, Université de Liège, Liège, Belgium.

This retrospective case series describes imaging findings in seven dogs and two cats with a presumptive diagnosis of sclerosing encapsulating peritonitis (SEP) between 2014 and 2021. Peritoneal effusion was present in all animal patients. Sonographically, echogenic fluid with or without echogenic intraperitoneal septations, gathered or corrugated bowel loops, and abdominal lymphadenomegaly were suggesting an inflammatory process and the presence of adhesions. Read More

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Effect of early-life exposure to PM on childhood asthma/wheezing: a birth cohort study.

Pediatr Allergy Immunol 2022 Jun;33(6)

Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China.

Background: Although studies have investigated the association between early-life exposure to fine particulate matter (PM ) and childhood asthma/wheezing, results are inconsistent and the susceptible exposure window remains largely unknown.

Methods: A prospective birth cohort study was conducted to recruit pregnant women during their early pregnancy, and to follow up them and their children up to 3-4 years old. Diagnosis of asthma/wheezing was extracted from children's medical records. Read More

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Impact of vaccinating pregnant women against pertussis on hospitalizations of children under one year of age in a tertiary hospital in Catalonia.

Enferm Infecc Microbiol Clin (Engl Ed) 2022 Jun 22. Epub 2022 Jun 22.

Servicio de Medicina Preventiva y Epidemiología, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Campus Hospitalari, Barcelona, Spain.

Introduction: The recommendation for pertussis vaccination in pregnancy was established in Catalonia in February 2014. The objective of this study was to compare the hospitalisation rate for pertussis in children under one year of age before and after the implementation of the vaccination programme.

Methods: Observational and retrospective study of patients under one year of age admitted to hospital with a diagnosis of pertussis. Read More

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Frequency of unscheduled visits to the Obstetrical Triage Assessment unit by pregnant adolescents in an urban Canadian Center compared to a matched cohort of pregnant women.

J Obstet Gynaecol Can 2022 Jun 22. Epub 2022 Jun 22.

Division of Pediatric and Adolescent Gynecology, Department of Surgery, Children's Hospital of Eastern Ontario; University of Ottawa, Department of Obstetrics and Gynecology, Ottawa, Canada; Clinical Research Unit, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, Ottawa, Canada.

Objectives: People from marginalized and vulnerable populations present more frequently for unscheduled, emergency obstetrical services at labour and delivery triage units. Based on our clinical experience, pregnant adolescents visit the obstetrical triage assessment units (OTAU) more often than adults do. This study was designed to assess this phenomenon by quantifying and describing the frequency of unscheduled visits to the OTAU by pregnant adolescents (age <20 y) compared with a matched cohort of adult pregnant patients (age ≥20 y). Read More

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Craniopagus and rachiopagus conjoined twins in triplet pregnancy: pitfalls of early prenatal diagnosis at 12 weeks.

Ultrasound Obstet Gynecol 2022 Jun 25. Epub 2022 Jun 25.

Department of Obstetrics and Gynecology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, The People's Republic of China (PRC).

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Learning deep neural networks' architectures using differential evolution. Case study: Medical imaging processing.

Smaranda Belciug

Comput Biol Med 2022 Jul 17;146:105623. Epub 2022 May 17.

Department of Computer Science, Faculty of Sciences, University of Craiova, Craiova, 200585, Romania. Electronic address:

The COVID-19 pandemic has changed the way we practice medicine. Cancer patient and obstetric care landscapes have been distorted. Delaying cancer diagnosis or maternal-fetal monitoring increased the number of preventable deaths or pregnancy complications. Read More

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Development of the Sepsis-Associated Adverse Outcomes in Pregnancy Score.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Obstetrics & Gynecology, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, United States.

Objective: To develop and evaluate a scoring system-called Sepsis-Associated Adverse Outcomes in Pregnancy (SAAP) Score-to identify individuals with maternal infection that have composite maternal adverse outcomes (CMAO).

Study Design: Using ICD codes, we identified pregnant and postpartum (up to 6 weeks after birth) individuals admitted at our center with a primary diagnosis of infection. The primary outcome was CMAO, which included any of the following: maternal intensive care unit admission, surgical intervention, vasopressor use, acute respiratory distress syndrome, pulmonary edema, mechanical ventilation, high flow nasal cannula, disseminated intravascular coagulation, dialysis, organ failure, venous thromboembolism, or maternal death. Read More

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Impaired fasting glucose in pregnancy: improved perinatal outcomes with active glycemic management.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Perinatology, Kaiser Permanente Oakland Medical Center, Oakland, United States.

Objective: To assess the association between active glycemic management and large for gestational age (LGA) neonates and cesarean delivery (CD) among pregnant women with impaired fasting glucose (IFG).

Study Design: Retrospective cohort study using electronic health record data of women with IFG who delivered at Kaiser Permanente Northern California from 2012-2017. IFG was defined as isolated fasting glucose ≥95 mg/dL. Read More

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Maternal obesity-associated disruption of polarized lactate transporter MCT4 expression in human placenta.

Reprod Toxicol 2022 Jun 22;112:1-6. Epub 2022 Jun 22.

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address:

Maternal obesity is associated with an increased risk of adverse pregnancy outcomes including stillbirth, and their etiology is thought to be related to placental and fetal hypoxia. In this study, we sought to investigate the levels of lactate in maternal and umbilical cord blood, a well characterized biomarker for hypoxia, and expression of plasma membrane lactate transporter MCT1 and MCT4 in the placental syncytiotrophoblast (STB), which are responsible for lactate uptake and extrusion, respectively, from pregnant women with a diagnosis of obesity following a Cesarean delivery at term. With use of approaches including immunofluorescence staining, Western blot, RT-qPCR and ELISA, our results revealed that in controls the expression of MCT1 was equally observed between basal (fetal-facing, BM) and microvillous (maternal-facing, MVM) membrane of the STB, whereas MCT4 was predominantly expressed in the MVM but barely detected in the BM. Read More

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Maternal Distress in Disclosing a Nonlethal Fetal Anomaly Diagnosis to Family and Friends.

MCN Am J Matern Child Nurs 2022 Jul-Aug 01;47(4):220-226

Purpose: To describe experiences of women disclosing a nonlethal fetal anomaly diagnosis to family and friends from initial prenatal diagnosis through postpartum.

Study Design And Methods: A descriptive, qualitative approach was used to explore women's perceptions of nonlethal fetal anomaly diagnosis in a high-risk obstetric clinic. In-depth interviews were conducted with 10 pregnant women, followed by postpartum interviews with 8 women. Read More

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Sex Hormone-Binding Globulin Level Enhances Prediction of Gestational Diabetes Mellitus in a Sub-Saharan African Population.

West Afr J Med 2022 Jun;39(6):580-587

Department of Chemical Pathology, Benue State University, Makurdi, Nigeria.

Background: The burden of Gestational Diabetes Mellitus (GDM) in the Sub-Saharan African region has been on the rise despite increased diagnosis and treatment. Current risk factor-based prediction approaches in the region lack strong predictive value, hence the need for effective early prediction and preventive interventions.

Aim: The aim of this study was to assess the diagnostic improvement in prediction of GDM by the addition of Sex Hormone-Binding Globulin (SHBG) assay to current approaches which assess early pregnancy maternal clinical risk factors in the study population. Read More

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Presepsin levels in neonatal cord blood are not influenced by maternal SARS-CoV-2 infection.

Clin Chem Lab Med 2022 Jun 24. Epub 2022 Jun 24.

Neonatology Unit, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.

Objectives: Coronavirus disease (COVID-19) can present with various symptoms and can involve multiple organs. Women infected during pregnancy have a higher incidence of obstetrical complications and infants born to "positive" mothers may get the infection with different manifestations. Presepsin seems to be a promising sepsis biomarker in adults and neonates. Read More

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Improving access to maternal health services among rural hard-to-reach fishing communities in Uganda, the role of community health workers.

Womens Health (Lond) 2022 Jan-Dec;18:17455057221103993

Ghent University International Centre for Reproductive Health, Ghent, Belgium.

Objectives: To explore whether community health worker household-based maternal health visits improve antenatal care and skilled birth attendance among hard-to-reach fishing villages on Lake Victoria, Uganda.

Methods: This quasi-experimental 18-month prospective study involved 486 consenting women aged 15-49 years, who were pregnant or had a pregnancy outcome in the past 6 months, from 6 island fishing communities. The community health worker household-based intervention (community health workers' household visits to provide counseling, blood pressure measurement, anemia, and HIV testing) involved 243 women from three fishing communities. Read More

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Advances in the ultrasound diagnosis in equine reproductive medicine: new approaches.

Reprod Domest Anim 2022 Jun 24. Epub 2022 Jun 24.

Laboratory of Equine Reproduction and Equine Spermatology, Veterinary Teaching Hospital, University of Extremadura, Cáceres, Spain.

Ultrasound technology has led to new lines of research in equine reproduction, and it has helped to greatly improve clinical diagnosis and reproductive outcomes in equine practice. This review aims to discuss the potential clinical uses and new approaches of ultrasonography in equine reproduction. Doppler modalities are usually used to evaluate the vascularization of the follicles, corpus luteum (CL), and the uterus in the mare for diagnostic purposes. Read More

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Rapid Quantification of Endogenous Steroids in Human Serum Using Leidenfrost Effect-Assisted Thermal Desorption Atmospheric Pressure Photoionization Orbitrap Mass Spectrometry.

J Am Soc Mass Spectrom 2022 Jun 24. Epub 2022 Jun 24.

National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029, China.

Unconjugated sex steroids in human serum play a crucial role in physiological and pathological studies and are frequently considered as biomarkers in clinical diagnosis. Because of their low polarity, poor volatility, and low concentration, the rapid and highly sensitive analysis of sex steroids in real serum matrix by ambient mass spectrometry is still challenging. Here, Leidenfrost effect-assisted thermal desorption atmospheric pressure photoionization orbitrap mass spectrometry (LETD-APPI-MS) was developed and applied to quantify free sex steroids in human serum without derivatization and chromatography separation within a few minutes. Read More

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Hepatitis C is associated with more adverse pregnancy outcomes than hepatitis B: A 7-year national inpatient sample study.

Hepatol Commun 2022 Jun 24. Epub 2022 Jun 24.

Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Prior international studies have shown mixed results regarding the association of hepatitis B and hepatitis C with adverse pregnancy outcomes. We performed an updated evaluation of the prevalence of associated adverse pregnancy outcomes and evaluated trends over time of diagnosis of chronic hepatitis B (HBV) and chronic hepatitis C (HCV) in pregnant women in a national database. All pregnant women with HBV and HCV were identified from the National Inpatient Sample database 2012 to 2018. Read More

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Machine Learning Model for Classifying the Results of Fetal Cardiotocography Conducted in High-Risk Pregnancies.

Yonsei Med J 2022 Jul;63(7):692-700

Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Korea.

Purpose: Fetal well-being is usually assessed via fetal heart rate (FHR) monitoring during the antepartum period. However, the interpretation of FHR is a complex and subjective process with low reliability. This study developed a machine learning model that can classify fetal cardiotocography results as normal or abnormal. Read More

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