396,711 results match your criteria Pregnancy Diagnosis


Pregnancy outcomes after maternal Zika virus infection in a non-endemic region: prospective cohort study.

Clin Microbiol Infect 2019 Feb 13. Epub 2019 Feb 13.

Maternal Fetal Medicine Unit. Department of Obstetrics. Hospital Universitari Vall d'Hebron. Ps. Vall d'Hebron 119-129, 08035 Barcelona. Universitat Autònoma de Barcelona.

Objectives: to describe pregnancy outcomes after Zika virus (ZIKV) infection in a non-endemic region.

Methods: according to the Spanish protocol issued after the ZIKV outbreak in Brazil in 2015, all pregnant women who had travelled to high-burden countries were screened for ZIKV. Serological and molecular tests were used to identify ZIKV-infected pregnant women. Read More

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http://dx.doi.org/10.1016/j.cmi.2019.02.008DOI Listing
February 2019

Imprint of parity and age at first pregnancy on the genomic landscape of subsequent breast cancer.

Breast Cancer Res 2019 Feb 15;21(1):25. Epub 2019 Feb 15.

Breast Cancer Translational Research Laboratory J.-C. Heuson, Institut Jules Bordet, Université Libre de Bruxelles (ULB), Brussels, Belgium.

Background: Although parity and age at first pregnancy are among the most known extrinsic factors that modulate breast cancer risk, their impact on the biology of subsequent breast cancer has never been explored in depth. Recent data suggest that pregnancy-induced tumor protection is different according to breast cancer subtypes, with parity and young age at first pregnancy being associated with a marked reduction in the risk of developing luminal subtype but not triple negative breast cancer. In this study, we investigated the imprint of parity and age at first pregnancy on the pattern of somatic mutations, somatic copy number alterations, transcriptomic profiles, and tumor immune microenvironment by assessing tumor-infiltrating lymphocytes (TILs) levels of subsequent breast cancer. Read More

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http://dx.doi.org/10.1186/s13058-019-1111-6DOI Listing
February 2019

Characterization and treatment of congenital thrombotic thrombocytopenic purpura.

Blood 2019 Feb 15. Epub 2019 Feb 15.

Department of Haematology, University College London Hospital, London, United Kingdom.

Congenital Thrombotic Thrombocytopenic Purpura (cTTP) is an ultra rare thrombomicroangiopathy caused by an inherited deficiency of ADAMTS13. There is limited data on the genotype-phenotype correlation and no consensus on treatment. We reviewed the largest cohort of cTTP cases, diagnosed in the UK, over the past 15 years. Read More

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http://dx.doi.org/10.1182/blood-2018-11-884700DOI Listing
February 2019

[Impact of the quality of ultrasound scan performed in gynecological emergencies in the diagnosis of ectopic pregnancy].

Gynecol Obstet Fertil Senol 2019 Feb 12. Epub 2019 Feb 12.

Service de Gynécologie Obstétrique, C.H.I. de Poissy Saint-Germain, Poissy, France; Unité de recherche EA 7285 - Risques cliniques et sécurité en santé des femmes et en santé périnatale (RISCQ), Université de Versailles-Saint-Quentin (UVSQ), Saint-Quentin-en-Yvelines, France.

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http://dx.doi.org/10.1016/j.gofs.2019.02.003DOI Listing
February 2019

A lower maternal cortisol to cortisone ratio precedes clinical diagnosis of preterm and term preeclampsia by many weeks.

J Clin Endocrinol Metab 2019 Feb 15. Epub 2019 Feb 15.

Department of Obstetrics and Gynaecology, NIHR Biomedical Research Centre, University of Cambridge, Cambridge, UK.

Context: Previous studies have shown reduced placental levels of 11-beta-hydroxysteroid dehydrogenase-type 2 (11βHSD2) in preeclampsia. However, it is not known if the maternal cortisol to cortisone ratio is predictive of placental complications of pregnancy.

Objective: To determine the relationship between the maternal serum cortisol to cortisone ratio at different stages of pregnancy and the risk of preeclampsia or fetal growth restriction (FGR). Read More

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http://dx.doi.org/10.1210/jc.2018-02312DOI Listing
February 2019

Emotional Experiences of Mothers Living With HIV and the Quest for Emotional Recovery: A Qualitative Study in Lima, Peru.

J Assoc Nurses AIDS Care 2019 Feb 13. Epub 2019 Feb 13.

Carmen Contreras, BA, is Director of Intervention Projects, Socios En Salud, Partners In Health, Lima, Peru. Nancy Rumaldo, BA, is a Project Coordinator, Socios En Salud, Partners In Health, Lima, Peru. Michael Masao Lindeborg, BA, is an MD candidate, Harvard Medical School, Boston, Massachusetts, USA. Milagros Mendoza, BA, is a Project Manager, Socios En Salud, Partners In Health, Lima, Peru. David Roy Chen, BA, is an MD candidate, University of Washington School of Medicine, Seattle, Washington, USA. Olga Saldaña, RN, is a Field Coordinator, Socios En Salud, Partners In Health, Lima, Peru. Milagros Wong, RN, is a Project Manager, Socios En Salud, Partners In Health, Lima, Peru. Maribel Muñoz, RN, is a Project Manager, Socios En Salud Partners In Health, Lima, Peru. Elizabeth Schrier, BA, is a Research Assistant, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. Leonid Lecca, MD, MPH, is a Lecturer on Global Health and Social Medicine, Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA, and Executive Director of Socios En Salud, Partners In Health, Lima, Peru. Arachu Castro, PhD, MPH, is the Samuel Z. Stone Endowed Chair of Public Health in Latin America, Department of Global Community Health and Behavioral Sciences, and Director of the Collaborative Group for Health Equity in Latin America (CHELA), Tulane School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA. Sonya Sunhi Shin, MD, MPH, is an Associate Physician of Infectious Disease, Division of Global Health Equity at Brigham and Women's Hospital, Boston, Massachusetts, USA. Adrianne Katrina Nelson, MPH, Msc, is a Research Manager, Division of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Little evidence exists about the emotional experiences of mothers with HIV, and a better understanding is essential to support their emotional health and treatment adherence. We describe the emotional experiences of eight mothers who initiated antiretroviral therapy during pregnancy or within a few years of childbirth in Lima, Peru. An interpretive phenomenological approach was used, and the following themes emerged: (a) emotions involved in diagnosis and disclosure, (b) the meaning of motherhood with HIV, (c) the mothers' roles in seeking and maintaining relationships with partners and families, and (d) mechanisms for resilience and emotional recovery. Read More

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http://dx.doi.org/10.1097/JNC.0000000000000051DOI Listing
February 2019
1.228 Impact Factor

[Establishment and one-year evaluation of an internal medicine consultation in a maternity].

Sante Publique 2018 September October;30(5):671-677

Objective: In the obstetric medicine movement and in response to requests for appointments in internal medicine by obstetricians and midwives, we created an internal medicine consultation within the maternity ward of our General Hospital, and provide feedback after 1 year.

Methods: This retrospective descriptive study took place at the Robert Ballanger Intercommunal Hospital Center in Aulnay-sous-Bois in Seine-Saint-Denis (France) between 3rd March 2016 and 9th March 2017, the first year of the internal medicine consultation, one afternoon every 15 days, in the maternity level 2b.

Results: Out of 121 appointments, 93 consultations were conducted for 63 patients. Read More

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http://dx.doi.org/10.3917/spub.186.0671DOI Listing
February 2019

A next generation sequencing custom gene panel designed to distinguish isolated polydactyly from syndromic polydactyly during prenatal diagnosis.

Congenit Anom (Kyoto) 2019 Feb 15. Epub 2019 Feb 15.

MAGI Euregio, Via Maso della Pieve, Bolzano, Italy.

Here we report a case of posthumous genetic testing on an aborted fetus. Voluntary termination of pregnancy was chosen after prenatal ultrasound examination showed polydactyly and renal cysts. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/cga.12328DOI Listing
February 2019

The psychopathology of NMDAR-antibody encephalitis in adults: a systematic review and phenotypic analysis of individual patient data.

Lancet Psychiatry 2019 Feb 11. Epub 2019 Feb 11.

Oxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom; Department of Neurology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address:

Background: Early immunotherapy administration improves outcomes in patients with N-methyl-D-aspartate receptor (NMDAR)-antibody encephalitis. As most patients with NMDAR-antibody encephalitis present to psychiatrists, the psychopathology of NMDAR-antibody encephalitis needs to be clearly defined to encourage accurate clinical identification and prompt treatment.

Methods: For this systematic review, we searched PubMed for all studies published in English between Jan 1, 2005, and Oct 7, 2017, to identify individually reported adult patients (≥18 years) who satisfied consensus criteria for definite NMDAR-antibody encephalitis. Read More

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http://dx.doi.org/10.1016/S2215-0366(19)30001-XDOI Listing
February 2019

The Diagnosis and Treatment of Carbon Monoxide Poisoning.

Dtsch Arztebl Int 2018 Dec;115(51-52):863-870

Department of Anaesthesiology and Intensive Care University Hospital Bonn (UKB), Bonn Clinic for Anesthesiology and Intensive Care Medicine, Hannover Medical School.

Background: The symptoms of carbon monoxide (CO) poisoning are nonspecific, ranging from dizziness and headache to unconsciousness and death. A German national guideline on the diagnosis and treatment of this condition is lacking at present.

Methods: This review is based on a selective literature search in the PubMed and Cochrane databases, as well as on existing guidelines from abroad and expert recommendations on diagnosis and treatment. Read More

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http://dx.doi.org/10.3238/arztebl.2018.0863DOI Listing
December 2018

Health system barriers to implementation of TB preventive strategies in South African primary care facilities.

PLoS One 2019 14;14(2):e0212035. Epub 2019 Feb 14.

Department of Epidemiology and Social Medicine (ESOC), University of Antwerp, Antwerp, Belgium.

Background: Isoniazid preventive therapy (IPT) is a key component of TB/HIV control, but few countries achieve high IPT coverage.

Methods: Using a behavioural COM-B design approach, the intervention consisted of a training on IPT guidelines and tuberculin skin testing (TST), identification of the optimal IPT implementation strategy by the health care workers (HCWs) of 3 primary care clinics, and a 2-month mentoring period. Using routine register data, TST and IPT uptake was determined 3 months before and 5 months after the intervention. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212035PLOS
February 2019

Twin anemia-polycythemia sequence and routine monitoring practices amongst maternal-fetal medicine specialists in the United States: an initial investigation.

J Perinat Med 2019 Feb 14. Epub 2019 Feb 14.

Kent State University, College of Public Health, Kent, OH, USA.

Background The purpose of this initial investigation was to begin to understand the routine twin anemia-polycythemia sequence (TAPS) monitoring practices of maternal-fetal medicine specialists (MFM specialists) in the United States in the absence of a formal guideline. Methods This study used an anonymous, online survey of 90 MFM specialists who were practicing in the United States. A $5 gift card to an online store was used to incentivize participants. Read More

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http://dx.doi.org/10.1515/jpm-2018-0240DOI Listing
February 2019

Heterotopic pregnancy - how easily you can go wrong in diagnosing? A case study.

J Ultrason 2018 ;18(75):355-358

1st Department of Obstetrics and Gynecology, Centre of Postgraduate Medical Education , Warsaw , Poland.

Heterotopic pregnancy is a rare, but potentially life-threatening pathology. The diagnosis of heterotopic pregnancy is still one of the biggest challenges in modern gynecology. The incidence of those pregnancies in natural conception is about 1:30000. Read More

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http://jultrason.pl/index.php/issues/volume-18-no-75/heterot
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http://dx.doi.org/10.15557/JoU.2018.0052DOI Listing
January 2018
2 Reads

The incidence of unexpected poor ovarian response in Chinese young women.

Medicine (Baltimore) 2019 Feb;98(7):e14379

School of Medical and Life Science/Reproductive & Women-Children Hospital, Chengdu University of Traditional Chinese Medicine.

Unexpected poor ovarian response (UPOR) is a problem for both clinicians and infertile couples, because our understanding of this situation is limited. This article investigated incidence of UPOR in women <35 years with normal ovarian reserve function with further analysis.This is a retrospective study, which included 567 women who accepted their first IVF-ET/ICSI. Read More

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http://dx.doi.org/10.1097/MD.0000000000014379DOI Listing
February 2019

An evaluation of sexually transmitted infection and odds of preterm or early term birth using propensity score matching.

Sex Transm Dis 2019 Feb 11. Epub 2019 Feb 11.

California Preterm Birth Initiative, University of California San Francisco, San Francisco, California, USA.

Background: Few studies have examined the relationship between sexually transmitted infections (STIs) and preterm birth (<37 weeks gestation) by subtype (<32 weeks, 32 - 36 weeks, spontaneous, provider-initiated). Here, we evaluate the odds of preterm (by subtype) and early term (37 and 38 weeks gestation) birth in women with an STI compared to a propensity score matched reference population.

Methods: The sample was selected from California births in 2007-2012. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000985DOI Listing
February 2019

Sero-diagnosis of brucellosis in sheep and humans in Assiut and El-Minya governorates, Egypt.

Int J Vet Sci Med 2018 9;6(Suppl):S63-S67. Epub 2018 Feb 9.

Department of Theriogenology, Faculty of Veterinary Medicine, Minia University, El Minya, Egypt.

Egypt is an endemic area with brucellosis, so wherever herd problem associated abortion is present, brucellosis should be suspected, and its sero-diagnosis is needed. The present study aimed to estimate the seroprevalence of brucellosis in sheep and their contact humans in Assiut and El-Minya Governorates where a history of abortion in sheep was the chief complaint of the farmers; besides; the appearance of signs of undulant fever among some contact humans. Also, to identify the risk factors for brucellosis seropositivity at human and animal level. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23144599173010
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http://dx.doi.org/10.1016/j.ijvsm.2018.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161859PMC
February 2018
1 Read

EQUIPTT: The Evaluation of the QUiPP app for Triage and Transfer protocol for a cluster randomised trial to evaluate the impact of the QUiPP app on inappropriate management for threatened preterm labour.

BMC Pregnancy Childbirth 2019 Feb 13;19(1):68. Epub 2019 Feb 13.

Division of Women's Health, Faculty of Life Sciences & Medicine, King's College London, 10th Floor, North Wing, St Thomas's Hospital Campus, London, SE1 7EH, UK.

Background: Accurate diagnosis of preterm labour is needed to ensure correct management of those most at risk of preterm birth and to prevent the maternal and fetal risks incurred by unnecessary interventions given to the large majority of women, who do not deliver within a week of presentation. Intervention "just-in-case" results in many avoidable admissions, women being transferred out of their local hospital unnecessarily and most women receiving unwarranted drugs, such as steroids and tocolytics. It also precludes appropriate transfers for others as neonatal cots are blocked pre-emptively, resulting in more dangerous ex-utero transfers. Read More

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http://dx.doi.org/10.1186/s12884-019-2210-1DOI Listing
February 2019

Complex decisions: correlates of injectable contraceptive discontinuation following HIV-1 seroconversion in an HIV prevention trial.

AIDS Care 2019 Feb 13:1-8. Epub 2019 Feb 13.

b David Geffen School of Medicine , University of California , Los Angeles.

Contraceptive adherence during acute and recent HIV-1 infection is important to maternal and child health given the elevated risk of vertical HIV-1 transmission and additional complications of pregnancy. Injectable contraception (IC) is the most common non-barrier modern contraception method used in sub-Saharan Africa (SSA). Adherence to IC after HIV-1 seroconversion is not well understood. Read More

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https://www.tandfonline.com/doi/full/10.1080/09540121.2019.1
Publisher Site
http://dx.doi.org/10.1080/09540121.2019.1580345DOI Listing
February 2019
2 Reads

DDT and Breast Cancer: Prospective Study of Induction Time and Susceptibility Windows.

J Natl Cancer Inst 2019 Feb 13. Epub 2019 Feb 13.

Background: In a previous Child Health and Development Studies report, p, p'-DDT was associated with a fivefold increased risk of premenopausal (before age 50 years) breast cancer for women first exposed before puberty. Here we extend our observation to breast cancer diagnosed during early postmenopause (ages 50-54 years) to determine whether age at diagnosis modifies the interaction of DDT with age at exposure.

Methods: We conducted a second prospective, nested case-control study in the Child Health and Development Studies (153 incident breast cancer cases diagnosed at ages 50-54 years and 432 controls matched to cases on birth year). Read More

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http://dx.doi.org/10.1093/jnci/djy198DOI Listing
February 2019

Is there a future for cell-free fetal dna tests in screening for preeclampsia?

Ginekol Pol 2019 ;90(1):55-60

First Department of Obstetrics and Gynaecology, Medical University of Warsaw, Poland.

CffDNA screening is a powerful diagnostic tool in the prenatal diagnosis algorithm for chromosomal abnormalities. With detailed ultrasound examination as the mainstay of first-trimester risk assessment, cffDNA has been shown to be superior to first-trimester combined screening (FTCS) in false-positive rates for trisomy 21 detection. In light of the growing interest in cffDNA testing and the possibility of it replacing first-trimester biochemistry, we decided to investigate the usefulness of cffDNA tests in early-pregnancy risk assessment for preeclampsia (PE). Read More

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http://dx.doi.org/10.5603/GP.2019.0009DOI Listing
January 2019
1 Read

Preimplantation genetic testing using Karyomapping for a paternally inherited reciprocal translocation: a case study.

J Assist Reprod Genet 2019 Feb 12. Epub 2019 Feb 12.

Monash IVF, Suite 1, 252 Clayton Rd, Clayton, Victoria, 3168, Australia.

Purpose: Preimplantation genetic testing (PGT) using Karyomapping is used to screen embryos for single gene disorders prior to implantation. While Karyomapping is not designed to screen for abnormalities in chromosome copy number, this testing is based upon a genome-wide analysis of single nucleotide polymorphisms (SNP) and, as such, some chromosome abnormalities are detected. The aim of this study was to validate whether Karyomapping could provide reliable and accurate PGT for a paternal 46,XY,t(10;19)(p15;p13. Read More

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http://dx.doi.org/10.1007/s10815-019-01413-0DOI Listing
February 2019

HSV Hepatitis in Pregnancy: A Review of the Literature.

Obstet Gynecol Surv 2019 Feb;74(2):93-98

Staff Physician, University of Arkansas for Medical Sciences, Little Rock, AR.

Importance: Herpes simplex virus (HSV) hepatitis is a rare condition with a high mortality rate. Immunocompromised individuals, including pregnant women, are the most susceptible. When primary infection occurs during pregnancy, risk for disseminated HSV is greatly increased. Read More

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http://dx.doi.org/10.1097/OGX.0000000000000642DOI Listing
February 2019

A 32-Year-Old Woman with Relapsing Pneumonia.

Eur J Case Rep Intern Med 2018 28;5(8):000854. Epub 2018 Aug 28.

Pneumology Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal.

Introduction: Isolated right pulmonary artery agenesis in an adult patient is an extremely rare condition that requires a high level of suspicion to make the diagnosis.

Case Description: A 32-year-old woman presented to the emergency room with a 4-month history of recurrent respiratory infections. Chest radiography and computerized tomography (CT) revealed alveolar opacities on the medium and inferior right lobes. Read More

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http://dx.doi.org/10.12890/2018_000854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346833PMC

Inflammatory Syndrome as the Initial Manifestation of Retroperitoneal Tuberculosis in a Pregnant Woman.

Eur J Case Rep Intern Med 2018 26;5(7):000865. Epub 2018 Jul 26.

Division of Pulmonary Diseases, Department of Internal Medicine Specialties, University Hospitals of Geneva, Switzerland.

A 20-year-old asylum seeker presented with vomiting and left thigh pain, with a biological inflammatory syndrome. Pregnancy was diagnosed. Investigations revealed a pseudo-cystic, 20-cm-long retroperitoneal abscess, biopsy of which confirmed the diagnosis of tuberculosis. Read More

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http://dx.doi.org/10.12890/2018_000865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346775PMC

Prenatal care of women who give birth to children with fetal alcohol spectrum disorder in a universal health care system: a case-control study using linked administrative data.

CMAJ Open 2019 Jan-Mar;7(1):E63-E72. Epub 2019 Feb 11.

Department of Community Health Sciences (Singal, Brownell, Chateau, Roos), Department of Paediatrics and Child Health (Hanlon-Dearman, Longstaffe) and Manitoba Centre for Health Policy (Brownell, Chateau), University of Manitoba, Winnipeg, Man.; Department of Pediatrics (Wall-Wieler), Stanford University, Stanford, Calif.

Background: Few studies have investigated prenatal care use among women who use alcohol during pregnancy. The objective of this study was to investigate rates of prenatal care usage of women who have given birth to children with fetal alcohol spectrum disorder (FASD).

Methods: We conducted a case-control study of women with children born in Manitoba between Apr. Read More

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http://dx.doi.org/10.9778/cmajo.20180027DOI Listing
February 2019

Determinants of Neurodevelopment in Early Childhood - Results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC ) Mother-Child Cohort.

Acta Paediatr 2019 Feb 12. Epub 2019 Feb 12.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

Aim: The objective of this study was to identify possible pre- and postnatal factors influencing neurodevelopment of the young child.

Methods: We used data from the Copenhagen Prospective Studies on Asthma in Childhood 2010 (COPSAC ) mother-child cohort, but excluded those with a neurological diagnosis, born <37 weeks of gestation and birth weights <2500g, resulting in 650 children analyzed. Neurodevelopment was assessed as age of achievement of early milestones, language scores at 1 and 2 years and cognitive score at 2 ½ years of age. Read More

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http://dx.doi.org/10.1111/apa.14753DOI Listing
February 2019
1 Read

Classification of Rectus Diastasis-A Proposal by the German Hernia Society (DHG) and the International Endohernia Society (IEHS).

Front Surg 2019 28;6. Epub 2019 Jan 28.

Hernienzentrum Köln, PAN-Klinik, Köln, Germany.

Recently, the promising results of new procedures for the treatment of rectus diastasis with concomitant hernias using extraperitoneal mesh placement and anatomical restoration of the linea alba were published. To date, there is no recognized classification of rectus diastasis (RD) with concomitant hernias. This is urgently needed for comparative assessment of new surgical techniques. Read More

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http://dx.doi.org/10.3389/fsurg.2019.00001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360174PMC
January 2019
1 Read

Expression, Regulation, and Function of the Calmodulin Accessory Protein PCP4/PEP-19 in Myometrium.

Reprod Sci 2019 Feb 11:1933719119828072. Epub 2019 Feb 11.

1 Department of Obstetrics and Gynecology, Division of Research, University of Kansas School of Medicine, Kansas City, KS, USA.

Objective:: Calmodulin (CaM) plays a key role in the orchestration of Ca signaling events, and its regulation is considered an important component of cellular homeostasis. The control of uterine smooth muscle function is largely dependent on the regulation of Ca and CaM signaling. The objective of this study was to investigate the expression, function, and regulation of CaM regulatory proteins in myometrium during pregnancy. Read More

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http://dx.doi.org/10.1177/1933719119828072DOI Listing
February 2019
3 Reads

Pregnancy and donor-specific HLA-antibody-mediated rejection after liver transplantation: "Liaisons dangereuses"?

Transpl Immunol 2019 Feb 8. Epub 2019 Feb 8.

Etablissement Français du Sang, Lyon, France.

Background: Risk factors for the development of anti-HLA antibodies include blood transfusion, organ transplantation, and pregnancy. Humoral rejection, mediated by donor-specific anti-HLA antibodies (DSA), has been studied in all kind of solid organ transplantations, and several studies have suggested that post-liver transplantation (LT) DSA may play a role in acute and chronic rejection.

Objective: The aim of the present study was to assess the impact of pregnancy on the occurrence of DSA and the impact of DSA in a large population of young female LT recipients. Read More

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http://dx.doi.org/10.1016/j.trim.2019.02.002DOI Listing
February 2019
1 Read

Venous Thromboembolism Among Women Initiating Depot Medroxyprogesterone Acetate Immediately Postpartum.

Obstet Gynecol 2019 Feb 4. Epub 2019 Feb 4.

Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, and Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, Tennessee.

Objective: To estimate the absolute and relative risk of venous thromboembolism (VTE) among women who initiate depot medroxyprogesterone acetate (DMPA) immediately postpartum compared with those who do not initiate hormonal contraception.

Methods: The IBM MarketScan Commercial Claims and Encounters databases were used to identify delivery hospitalizations among women aged 15-44 years during 2005 through 2014. Diagnosis, procedure, and drug codes were used to identify contraception, VTE, and potential confounding chronic or pregnancy-related conditions. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003135DOI Listing
February 2019
1 Read

The management of hydatidiform mole with lung nodule: a retrospective analysis in 53 patients.

J Gynecol Oncol 2018 Nov 23. Epub 2018 Nov 23.

Women's Reproductive Health Laboratory of Zhejiang Province, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Objective: To investigate the significance of lung nodule in hydatidiform mole, we retrospectively compared the clinical outcomes of those patients treated with different strategies.

Methods: The patients were divided into three groups: chemotherapy immediately once lung nodule was detected (group 1, n=17), delayed chemotherapy until human chorionic gonadotrophin (hCG) level met the diagnostic criteria for gestational trophoblastic neoplasia (GTN) (group 2, n=18), and hCG surveillance alone until hCG level was normalized spontaneously (group 3, n=18). The clinical parameters of these patients were collected and analyzed. Read More

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https://ejgo.org/DOIx.php?id=10.3802/jgo.2019.30.e16
Publisher Site
http://dx.doi.org/10.3802/jgo.2019.30.e16DOI Listing
November 2018
2 Reads

Congenital clubfoot in Europe: A population-based study.

Am J Med Genet A 2019 Feb 10. Epub 2019 Feb 10.

Paediatric Department, Hospital Lillebaelt Kolding, Kolding, Denmark.

We aimed to assess prevalence, birth outcome, associated anomalies and prenatal diagnosis of congenital clubfoot in Europe using data from the EUROCAT network, and to validate the recording of congenital clubfoot as a major congenital anomaly by EUROCAT registries. Cases of congenital clubfoot were included from 18 EUROCAT registries covering more than 4.8 million births in 1995-2011. Read More

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http://dx.doi.org/10.1002/ajmg.a.61067DOI Listing
February 2019
1 Read

Herpes Zoster in Pregnancy.

J Midwifery Womens Health 2019 Feb 10. Epub 2019 Feb 10.

Vanderbilt University School of Nursing, Nashville, Tennessee.

Herpes zoster (shingles) is the reactivation of dormant varicella zoster virus in individuals who previously experienced varicella infection or vaccination. Herpes zoster can occur in pregnancy, although it is rare. This case report describes the clinical presentation and diagnosis of herpes zoster and reviews current recommendations for treatment. Read More

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http://dx.doi.org/10.1111/jmwh.12953DOI Listing
February 2019
1 Read

Vascular transfer of lidocaine between monochorionic twins with no apparent signs.

Ultrasound Obstet Gynecol 2019 Feb 10. Epub 2019 Feb 10.

Center for Fetal Therapy - Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine Baltimore, Maryland, United States.

A 30-year old, nullipara presented with a dichorionic triamniotic triplet pregnancy at 18 weeks gestation with diagnosis of stage IV twin-twin transfusion syndrome (TTTS) and severe cervical shortening (cervical length of 4 mm). After extensive counselling she opted for selective reduction of the monochorionic pair and amnioreduction. This article is protected by copyright. Read More

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http://dx.doi.org/10.1002/uog.20237DOI Listing
February 2019
1 Read

"It Can't Be Like Last Time" - Choices Made in Early Pregnancy by Women Who Have Previously Experienced a Traumatic Birth.

Front Psychol 2019 25;10:56. Epub 2019 Jan 25.

Faculty of Health Sciences, University of Hull, Hull, United Kingdom.

A significant number of women experience childbirth as traumatic. These experiences are often characterized by a loss of control coupled with a perceived lack of support and inadequate communication with health care providers. Little is known about the choices women make in subsequent pregnancy(s) and birth(s), or why they make these choices. Read More

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http://dx.doi.org/10.3389/fpsyg.2019.00056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355667PMC
January 2019
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Ruptured renal artery aneurysm in pregnancy and puerperium: literature review of 53 cases.

Arch Gynecol Obstet 2019 Feb 9. Epub 2019 Feb 9.

Department of Internal Medicine, University Hospital Centre Zagreb and School of Medicine University of Zagreb, Kišpatićeva 12, 10000, Zagreb, Croatia.

Purpose: To summarize and define the most appropriate diagnostic methods and therapeutic options for ruptured renal artery aneurysms in pregnancy based on rarely published data.

Methods: Literature searches of English-, German-, Spanish-, and Italian-language articles were performed in PubMed (1946-2018), PubMed Central (1900-2018) and Google Scholar. The search terms included renal artery aneurysm, renal artery rupture, pregnancy, puerperium, nierenarterienaneurysma, schwangerschaft, wochenbett, aneurisma de la arteria renal, el embarazo, puerperio, aneurisma dell'arteria renale and gravidanza. Read More

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http://dx.doi.org/10.1007/s00404-019-05087-yDOI Listing
February 2019

[Lupus nephritis].

Nephrol Ther 2019 Feb 7. Epub 2019 Feb 7.

Service de néphrologie, hôpital Bichat, 46, rue Henri-Huchard, 75877 Paris cedex 18, France; Université Paris Diderot, 5, rue Thomas-Mann, 75013 Paris, France; Inserm U1149, Département hospitalo-universitaire (DHU) Fibrosis-Inflammation-Remodeling (FIRE), 16, rue Henri Huchard, 75890 Paris cedex 18, France. Electronic address:

Systemic lupus erythematosus is the most characteristic of auto-immune disorders that can lead to tissue damage in many organs, including kidney. Lupus nephritis occurs in 10 to 40% of lupus patients. Its clinical hallmark is the appearance of a proteinuria as soon as a 0. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17697255183065
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http://dx.doi.org/10.1016/j.nephro.2018.11.003DOI Listing
February 2019
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Syphilis.

Enferm Infecc Microbiol Clin 2019 Feb 6. Epub 2019 Feb 6.

Servicio de Microbiología, Hospital Universitario de Cabueñes, Gijón, Asturias, España; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Asturias, España; Grupo de Estudio de ITS de la SEIMC (GEITS), Madrid, España.

Syphilis is an infectious disease caused by the spirochaete Treponema pallidum subsp. pallidum which is transmitted by sexual contact or vertical transmission during pregnancy. The incidence of syphilis has increased in the last years, mainly among men who have sex with men. Read More

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http://dx.doi.org/10.1016/j.eimc.2018.12.009DOI Listing
February 2019
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Exacerbation of Cushing's syndrome during pregnancy: stimulation of a cortisol-secreting adrenocortical adenoma by ACTH originating from the foeto-placental unit.

Endocrinol Diabetes Metab Case Rep 2019 Feb 7;2019. Epub 2019 Feb 7.

A 29-year-old G4A3 woman presented at 25 weeks of pregnancy with progressive signs of Cushing's syndrome (CS), gestational diabetes requiring insulin and hypertension. A 3.4 × 3. Read More

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http://dx.doi.org/10.1530/EDM-18-0115DOI Listing
February 2019
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Levonorgestrel intrauterine contraceptive systems (13.5 mg and 52 mg) and risk of ectopic pregnancy.

Acta Obstet Gynecol Scand 2019 Feb 8. Epub 2019 Feb 8.

Department of Clinical Sciences, Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.

Introduction: The objective was to investigate the Pearl index for ectopic pregnancy in women using levonorgestrel intrauterine system (LNG-IUS) at time of conception.

Material And Methods: This was a sub-study of a hospital based historical cohort including women with an ectopic pregnancy diagnosed in four referral hospitals in Stockholm Sweden between December 2013 and April 2017. Study participants and type of contraception at time of conception were identified through the electronic medical chart system. Read More

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http://dx.doi.org/10.1111/aogs.13564DOI Listing
February 2019
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Complete recovery in Wernicke's encephalopathy complicating hyperemesis gravidarum.

BMJ Case Rep 2019 Feb 7;12(2). Epub 2019 Feb 7.

Department of Obstetrics and Gynecology, Jawaharlal Institute of Post-graduate Medical Education and Research, Pondicherry, India.

Wernicke's encephalopathy (WE) is an uncommon neurological complication in pregnancies complicated with hyperemesis due to thiamine deficiency. In women with hyperemesis, inadvertent glucose administration prior to thiamine supplementation triggers the development of neurological manifestations. Delay in the diagnosis can lead to maternal morbidity, and in one-third of cases may lead to persistence of some neurological deficit. Read More

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http://dx.doi.org/10.1136/bcr-2018-227530DOI Listing
February 2019
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Hsa_circRNA_0054633 is highly expressed in gestational diabetes mellitus and closely related to glycosylation index.

Clin Epigenetics 2019 Feb 8;11(1):22. Epub 2019 Feb 8.

Diabetes Research Center, Medical School, Ningbo University, 818 Fenghua Road, Ningbo, 315211, Zhejiang, China.

Background: Circular RNA (circRNA) is involved in the pathological processes of various diseases. CircRNA is more stable than linear RNAs and is expressed in high levels in tissues, making it a better biomarker candidate than linear RNAs. In this study, we aimed to identify potential circRNA biomarkers of gestational diabetes mellitus (GDM). Read More

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http://dx.doi.org/10.1186/s13148-019-0610-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368772PMC
February 2019
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Vaginal Ureaplasma parvum serovars and spontaneous preterm birth.

Am J Obstet Gynecol 2019 Feb 5. Epub 2019 Feb 5.

Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.

Background: Ureaplasma species (spp.) are the bacteria most often isolated from the amniotic cavity of women with preterm labor or preterm premature rupture of membranes, thus, the link between intrauterine Ureaplasma spp. infection and adverse pregnancy outcome is clearly established. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.237DOI Listing
February 2019
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Association between antibiotic treatment during pregnancy & infancy and the development of allergic diseases.

Pediatr Allergy Immunol 2019 Feb 8. Epub 2019 Feb 8.

University Children's Hospital Zurich, Switzerland.

Background: Allergies are a serious public health issue and prevalences are rising worldwide. The role of antibiotics in the development of allergies has repeatedly been discussed, as results remain inconsistent. The aim of this study was to investigate the association between pre- & postnatal antibiotic exposure and subsequent development of allergies (atopic dermatitis, food allergy, asthma, atopic sensitization and allergic rhinitis). Read More

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http://doi.wiley.com/10.1111/pai.13039
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http://dx.doi.org/10.1111/pai.13039DOI Listing
February 2019
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Epidemiology of mental disorders during pregnancy and link to birth outcome: a large-scale retrospective observational database study including 38,000 pregnancies.

Arch Gynecol Obstet 2019 Feb 8. Epub 2019 Feb 8.

Department of Obstetrics and Gynecology, University of Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Germany.

Purpose: To investigate the real-life epidemiology of mental disorders during pregnancy and their impact on birth outcome in an unselected low-risk population in Germany.

Methods: Claims data of the Techniker Krankenkasse (TK) were analyzed as part of a retrospective observational study over a one-year period from 01/2008 to 12/2008 including 38,174 pregnant women. ICD-10 codes were clustered into four diagnostic groups: depression, anxiety disorders, somatoform/dissociative disorders and acute stress reactions. Read More

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http://dx.doi.org/10.1007/s00404-019-05075-2DOI Listing
February 2019
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Effects of platforms, size filter cutoffs, and targeted regions of cytogenomic microarray on detection of copy number variants and uniparental disomy in prenatal diagnosis: Results from 5026 pregnancies.

Prenat Diagn 2019 Feb 8. Epub 2019 Feb 8.

Cytogenetics and Genomics, Quest Diagnostics Nichols Institute, San Juan Capistrano, California.

Objective: We evaluated the effects of platforms, size filter cutoffs, and targeted regions of cytogenomic microarray (CMA) on the detection of copy number variants (CNVs) and uniparental disomy (UPD) in prenatal diagnosis.

Methods: Five thousand twenty-six consecutive prenatal specimens (>98% high-risk pregnancy) were studied by high-resolution CMA, with cutoffs of 50 kb for losses and 200 kb for gains in nontargeted regions and 20 kb for losses and 100 kb for gains in targeted regions. We assessed actual detection rates using the current assay as well as hypothetical detection rates using platforms with the same or lower resolution and smaller or larger cutoffs. Read More

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http://dx.doi.org/10.1002/pd.5375DOI Listing
February 2019
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Chronic Candida osteomyelitis of hard palate and nose: A diagnostic quandary.

Med Mycol Case Rep 2019 Jun 14;24:1-4. Epub 2019 Jan 14.

Department of Microbiology, All India Institute of Medical Sciences, Jodhpur 2, Basni, Jodhpur 342005, India.

induced osteomyelitis is infrequent. There is scarcity of literature on this entity in maxillofacial region and thus there is possibility to mismanage such cases. We are presenting a case of chronic maxillofacial osteomyelitis causing palatal and septal perforation with saddle nose deformity in a young lady with commencement and progression of disease process over two pregnancies. Read More

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http://dx.doi.org/10.1016/j.mmcr.2019.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357845PMC
June 2019
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The impact of diagnostic criteria for gestational diabetes on its prevalence: a systematic review and meta-analysis.

Diabetol Metab Syndr 2019 1;11:11. Epub 2019 Feb 1.

1Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, No 24, Parvane Street, Yaman Street, Velenjak, Tehran, P.O.Box: 19395-4763, Iran.

Background: The absence of universal gold standards for screening of gestational diabetes (GDM) has led to heterogeneity in the identification of GDM, thereby impacting the accurate estimation of the prevalence of GDM. We aimed to evaluate the effect of different diagnostic criteria for GDM on its prevalence among general populations of pregnant women worldwide, and also to investigate the prevalence of GDM based on various geographic regions.

Methods: A comprehensive literature search was performed in PubMed, Scopus and Google-scholar databases for retrieving articles in English investigating the prevalence of GDM. Read More

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http://dx.doi.org/10.1186/s13098-019-0406-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359830PMC
February 2019

Serum concentrations of IGF-I/IGF-II as biomarkers of alcohol damage during foetal development and diagnostic markers of Foetal Alcohol Syndrome.

Sci Rep 2019 Feb 7;9(1):1562. Epub 2019 Feb 7.

Grup de Recerca Infancia i Entorn (GRIE), Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Foetal Alcohol Syndrome (FAS) is the most deleterious health effect derived from alcohol consumption during pregnancy and is placed at the end of the Foetal Alcohol Spectrum Disorders (FASD). Few studies have proposed potential molecular biomarkers of physical and neurological damage associated with prenatal alcohol exposure. We prospectively recruited 55 children from 8 to 12 years old, with a prenatal assessment for ethanol exposure using meconium analysis of fatty acid ethyl esters (FAEE). Read More

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http://dx.doi.org/10.1038/s41598-018-38041-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367511PMC
February 2019
1 Read