168,596 results match your criteria Pregnancy Delivery

Obstetrics outcome in pulmonary tuberculosis.

Indian J Tuberc 2022 Jul 7;69(3):305-310. Epub 2021 Jan 7.

Department of Obstetrics and Gynecology, AIIMS, New Delhi, India.

Background: To evaluate the maternal and perinatal outcome in pulmonary tuberculosis cases as compared to low risk pregnancies in a tertiary referral hospital.

Methods: A total of 15 cases of pulmonary tuberculosis over a period of two years who delivered in our unit was studied in the retrospective study. The maternal and perinatal outcome in them was compared with 191 low risk pregnancies who delivered at the same time in the hospital after taking into account inclusion and exclusion criteria. Read More

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Preconception Health in the Workplace: An Opportunity to Support Equitable Access to Education.

Semin Reprod Med 2022 Jun 27. Epub 2022 Jun 27.

Health and Social Care Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.

Preconception health is a key determinant of pregnancy and offspring outcomes, but challenges reaching people during preconception are frequently cited by health professionals. This article highlights the workplace as an important setting for promoting equitable access to preconception health-related information and education to support optimal well-being before pregnancy. Workplaces can support equitable access to education and knowledge for preconception health: (1) due to the high engagement of reproductive-age women in the workforce and (2) by reaching vulnerable or high-risk population groups who may otherwise face barriers to accessing preconception health information. Read More

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Risk factors for clinically significant intra-ventricular hemorrhage in pregnancies complicated by preterm premature rupture of membranes.

J Pregnancy Neonatal Med 2021 ;5(4)

Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, USA.

Objectives: Preterm birth is a major cause of adverse perinatal outcomes, including intraventricular hemorrhage (IVH). IVH has been shown to contribute to lasting neurological disability, however the role of maternal characteristics and potentially modifiable risk factors that contribute to these outcomes have not been well defined. We sought to determine predictors of IVH in pregnancies complicated by early preterm premature rupture of membranes (PPROM). Read More

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January 2021

[Clinical, obstetric and perinatal characteristics of Mexican pregnant women with COVID-19].

Rev Med Inst Mex Seguro Soc 2022 Mar 1;60(2):116-128. Epub 2022 Mar 1.

Instituto Mexicano del Seguro Social, Hospital de Gineco Obstetricia No. 4 "Luis Castelazo Ayala", División de Obstetricia. Ciudad de México, México.

Background: COVID-19 disease is the leading cause of maternal death in Mexico. The data published to date indicate that pregnancy favors severe forms of the disease.

Objective: To describe the clinical, obstetric and perinatal characteristics of pregnant women with COVID-19 disease treated at the UMAE "Luis Castelazo Ayala" of the Instituto Mexicano del Seguro Social. Read More

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An unexplained fetal intracranial hemorrhage with extensive and multifocal hemorrhagic lesions: A case report.

Medicine (Baltimore) 2022 Jun 24;101(25):e29335. Epub 2022 Jun 24.

Department of Obstetrics and Gynaecology, West China Second University Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children of the Ministry of Education, Sichuan University, No.20, Section 3, Renmin Nan Lu, Chengdu, Sichuan Province, China.

Rationale: Fetal intracranial hemorrhage (ICH) is an extremely rare complication of pregnancy, with subsequent neurological sequelae or fetal death. The diagnosis of fetal ICH is primarily based on ultrasound or magnetic resonance imaging.

Patient Concerns: An asymptomatic woman at 31 weeks of gestation was referred for a detailed anomaly scan because routine fetal ultrasonography showed suspected fetal ICH. Read More

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The natural occurring RRR-α-Tocopherol and Synthetic α-Tocopherol stereoisomers in maternal plasma, cord plasma and breast milk among six regions of China.

Br J Nutr 2022 Jun 27:1-25. Epub 2022 Jun 27.

School of Public Health, Shanghai JiaoTong University, Shanghai 200025, People's Republic of China.

Objective: The study aimed to investigate RRR-α-Tocopherol and synthetic α-Tocopherol stereoisomers in maternal plasma, cord plasma and breast milk from different regions of China, providing a reference for further guidance on maternal diet and the potential need to supplement mothers with vitamin E.

Methods: Two hundred and twenty-one sample sets from maternal plasma, cord plasma and three stages of milk (colostrum: 1-5 days after delivery; transitional milk:10-15 days; mature milk: 40-45 days) were collected longitudinally in six regions of Shanghai, Guangzhou, Tianjin, Chengdu, Lanzhou and Changchun. α-Tocopherol and the stereoisomers were determined by high performance liquid chromatography with a fluorescence detector. Read More

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Maternal cigarette smoking and alcohol consumption and congenital diaphragmatic hernia.

Birth Defects Res 2022 Jun 27. Epub 2022 Jun 27.

Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa.

Background: Congenital diaphragmatic hernia (CDH) occurs when abnormal diaphragm development allows herniation of abdominal organs into the thoracic cavity. Its etiopathogenesis is not well understood, but cigarette smoking and alcohol exposure may impact diaphragm development. Using data from a large, population-based case-control study, we examined associations between maternal cigarette smoking and alcohol consumption and CDH in offspring. Read More

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The relationship between prenatal attachment and postnatal adaptation, maternal anxiety and breast milk sodium level.

Compr Psychoneuroendocrinol 2021 Nov 9;8:100085. Epub 2021 Sep 9.

Lösante Hastanesi, Department of Pediatrics, Division of Developmental Pediatrics, Ankara, Turkey.

Objective: To investigate the relationship between maternal-fetal attachment and breast milk sodium (BMS) levels.

Methods: This prospective case-control study was conducted at Baskent University. Third-trimester low-risk pregnancies were included in the study. Read More

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November 2021

Best Practices for Managing Postpartum Hypertension.

Curr Obstet Gynecol Rep 2022 Jun 20:1-10. Epub 2022 Jun 20.

Department of Obstetrics and Gynecology, University of Pennsylvania Health System, 3400 Spruce Street, Philadelphia, PA 19104 USA.

Purpose Of Review: Patients remain at risk for persistent and de novo postpartum hypertension related to pregnancy. This review aims to summarize the current definitions, clinical practices, and novel systems innovations and therapies for postpartum hypertension.

Recent Findings: Recent changes to the definitions of hypertension outside of pregnancy have not yet impacted definitions or management of hypertensive disorders of pregnancy (HDP), though research examining the implications of these new definitions on risks of developing HDP and the resultant sequelae is ongoing. Read More

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Sudden Onset of Severe Pulmonary Hypertension in a Preterm Infant: A Case Report on the Role of Maternal Use of Serotonin Re-Uptake Inhibitors During Pregnancy and Concurrent Risk Factors.

Front Pediatr 2022 10;10:855419. Epub 2022 Jun 10.

Division of Neonatal and Pediatric Intensive Care, Emergency Department, IRCCS Giannina Gaslini Institute, Genoa, Italy.

Persistent pulmonary hypertension of the newborn (PPHN) is a severe condition caused by failed circulatory adaptation at birth. Pulmonary hypertension is most common in full-term infants and rare in preterms, although it is increasingly diagnosed also in extremely preterm infants. Previous studies demonstrated the association between maternal use of selective serotonin re-uptake inhibitors during gestation and pulmonary hypertension. Read More

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Evaluation of Antepartum Factors for Predicting the Risk of Emergency Cesarean Delivery in Pregnancies Complicated With Placenta Previa.

Ochsner J 2022 ;22(2):146-153

Department of Obstetrics and Gynecology, Health Sciences University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.

The optimal delivery timing for patients with placenta previa remains controversial in the literature. To reduce spontaneous vaginal bleeding rates, which occur increasingly with advancing gestational weeks, elective cesarean delivery is advocated between 36 and 37 weeks of gestation, but this clinical approach does not take into consideration numerous patient variables. Few papers identify the risk factors for emergency cesarean delivery in patients with placenta previa. Read More

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January 2022

Peripartum and Postpartum Analgesia and Pain in Women Prescribed Buprenorphine for Opioid Use Disorder Who Deliver by Cesarean Section.

Subst Abuse 2022 21;16:11782218221107936. Epub 2022 Jun 21.

Department of Pharmacy Practice, Westbrook College of Health Professions, University of New England, Portland, ME, USA.

Aim: Little is known about whether pain can be effectively managed in pregnant women with opioid use disorder (OUD) during delivery hospitalization, particularly those undergoing surgery and taking buprenorphine as medication for OUD (MOUD). To address this question, we compared pain scores and opioid analgesic utilization during delivery hospitalization in women taking their pre-hospital dose of buprenorphine who delivered by cesarean section to matched controls. To inform future research efforts, we also began to explore opioid analgesic utilization and pain scores by type of anesthesia as this variable is often not included in related literature. Read More

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Expanding the MYOD1 phenotype: A case report of a patient diagnosed whilst pregnant.

J Neuromuscul Dis 2022 Jun 20. Epub 2022 Jun 20.

Department of Neurogenetics, Royal Perth Hospital, Perth, WA, Australia.

A 38-year-old pregnant woman presented at 30 weeks gestation in respiratory distress with pre-eclampsia. This was on the background of slowly progressive dyspnoea over six years, with generalised weakness and previous surgery for ptosis and prognathia. After successful caesarean delivery at 31 weeks, the patient was found to have a homozygous likely pathogenic variant in the MYOD1 gene. Read More

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Now Is the Time to Safeguard Access to Emergency Contraception Before Abortion Restrictions Sweep the United States.

Contraception 2022 Jun 23. Epub 2022 Jun 23.

University of Utah, Salt Lake City, UT, United States.

Abortion and contraception are essential components of reproductive healthcare. As 26 states are likely to severely restrict access to abortion following the Supreme Court decision in Dobbs v. Jackson Women's Health Organization, access to emergency contraception will be more important than ever. Read More

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Ocrelizumab during pregnancy and lactation: Rationale and design of the MINORE and SOPRANINO studies in women with MS and their infants.

Mult Scler Relat Disord 2022 Jun 11;64:103963. Epub 2022 Jun 11.

Service de Neurologie et Sclérose en Plaques, Fondation Eugène Devic EDMUS contre la Sclérose en Plaques, Hôpital Neurologique Pierre Wertheimer, Lyon, France.

Background: Most disease-modifying therapies (DMTs) approved for the treatment of multiple sclerosis (MS) are not recommended during pregnancy, and discouraged while breastfeeding. However, discontinuation of some DMTs before pregnancy can leave women vulnerable to MS relapses. Although available data on ocrelizumab suggest no increased risk in terms of pregnancy or neonatal outcomes, it is unknown whether ocrelizumab transfers across the placenta or is absorbed through breastmilk; and if so, whether infant B cell development, immune responses or growth and development are affected. Read More

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Time-related Biases in Perinatal Pharmacoepidemiology: A Systematic Review of Observational Studies.

Pharmacoepidemiol Drug Saf 2022 Jun 26. Epub 2022 Jun 26.

Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada.

Background: Time-related biases, such as immortal time and time-window bias, frequently occur in pharmacoepidemiologic research. However, the prevalence of these biases in perinatal pharmacoepidemiology is not well understood.

Objective: To describe the frequency of time-related biases in observational studies of medications commonly used during pregnancy (antibiotic, antifungal, and antiemetic drugs) via systematic review. Read More

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The Prevalence and Outcome of Teenage Pregnancies in a Secondary Health Facility in Delta State, Nigeria: A Four-Year Retrospective Review.

West Afr J Med 2022 Jun;39:609-613

Department of Community Medicine, Faculty of Clinical Medicine, Delta State University, Abraka, Nigeria.

Introduction: This study determined the prevalence, obstetric characteristics and pregnancy outcomes in teenagers who delivered at a secondary health facility in a Southern State in Nigeria.

Materials And Methods: A retrospective study was employed to review pregnancies that were managed in Central Hospital Warri, Delta State, Nigeria between 2014-2017. Patients' notes were retrieved and analyzed with respect to the socio-demographic characteristics, pregnancy, labor and delivery complications and fetal outcome. Read More

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Delayed versus early umbilical cord clamping for near-term infants born to preeclamptic mothers; a randomized controlled trial.

BMC Pregnancy Childbirth 2022 Jun 25;22(1):515. Epub 2022 Jun 25.

Obstetrics and Gynaecology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Objective: This study aims to assess delayed versus early umbilical cord clamping in preeclamptic mothers undergoing scheduled caesarean delivery regarding the maternal intra-operative blood loss and neonatal outcomes.

Methods: A clinical trial was conducted on 62 near-term preeclamptic mothers (36-38 weeks) who were planned for caesarean delivery. They were randomly assigned into two groups. Read More

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Frequency of unscheduled visits to the Obstetrical Triage Assessment unit by pregnant adolescents in an urban Canadian Center compared to a matched cohort of pregnant women.

J Obstet Gynaecol Can 2022 Jun 22. Epub 2022 Jun 22.

Division of Pediatric and Adolescent Gynecology, Department of Surgery, Children's Hospital of Eastern Ontario; University of Ottawa, Department of Obstetrics and Gynecology, Ottawa, Canada; Clinical Research Unit, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, Ottawa, Canada.

Objectives: People from marginalized and vulnerable populations present more frequently for unscheduled, emergency obstetrical services at labour and delivery triage units. Based on our clinical experience, pregnant adolescents visit the obstetrical triage assessment units (OTAU) more often than adults do. This study was designed to assess this phenomenon by quantifying and describing the frequency of unscheduled visits to the OTAU by pregnant adolescents (age <20 y) compared with a matched cohort of adult pregnant patients (age ≥20 y). Read More

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An Emerging Pattern? A Further Case of Anticipated Capacity Loss in Pregnancy: North Middlesex University Hospital NHS Trust V SR [2021] EWCOP 58.

Aimee V Hulme

Med Law Rev 2022 Jun 25. Epub 2022 Jun 25.

School of Law and Social Justice, University of Liverpool, Liverpool L69 7ZR, UK.

In 2021, the Court of Protection made a third anticipatory declaration that it was lawful for a capacitous pregnant woman to be subject to possible forcible treatment contingent on her losing capacity before or during birth. North Middlesex University Hospital v SR raises three interesting questions for discussion which this commentary will explore. First, it is submitted that there is a growing, yet alarming, trend in the use of anticipatory or contingent declarations to manage such challenging cases of future loss of, or fluctuating, capacity in pregnant women. Read More

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Risk factors of anaemia among postpartum women in Bolgatanga Municipality, Ghana.

BMC Nutr 2022 Jun 24;8(1):58. Epub 2022 Jun 24.

Department of Nutritional Sciences, School of Allied Health Sciences, University for Development Studies, P. O. Box TL 1883, Tamale, Ghana.

Introduction: Anaemia is a major public health problem affecting women of reproductive age globally. This study was conducted to assess the prevalence and determinants of anaemia among postpartum women in Bolgatanga Municipality, Ghana.

Methods: The study employed an analytical cross-sectional study design to recruit 405 women who delivered in the last 6 weeks from 9 health facilities in the Municipality. Read More

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Prevalence and predictors of elective and emergency caesarean delivery among reproductive-aged women in Bangladesh: evidence from demographic and health survey, 2017-18.

BMC Pregnancy Childbirth 2022 Jun 24;22(1):512. Epub 2022 Jun 24.

Department of Population and Development, International Institute for Population Sciences, Deonar East, Mumbai, 400088, Maharashtra, India.

Background: Over the years, an increasing trend of unnecessary caesarean section (c-section) deliveries has raised concerns in Bangladesh. So far, many studies have reported the risk factors of c-section delivery in Bangladesh. However, most of these studies did not estimate the predictors of the two c-section procedures (i. Read More

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Impaired fasting glucose in pregnancy: improved perinatal outcomes with active glycemic management.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Perinatology, Kaiser Permanente Oakland Medical Center, Oakland, United States.

Objective: To assess the association between active glycemic management and large for gestational age (LGA) neonates and cesarean delivery (CD) among pregnant women with impaired fasting glucose (IFG).

Study Design: Retrospective cohort study using electronic health record data of women with IFG who delivered at Kaiser Permanente Northern California from 2012-2017. IFG was defined as isolated fasting glucose ≥95 mg/dL. Read More

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Being a mother under the COVID-19 pandemic lockdown: Evaluation of perinatal anxiety, prenatal attachment, and maternal-infant attachment.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Obstetrics and Gynecology, TC Saglik Bakanligi Izmir Il Saglik Mudurlugu Izmir Saglik Bilimleri Universitesi Tepecik Egitim ve Arastirma Hastanesi, Izmir, Turkey.

Objectives: The COVID-19 pandemic has caused both physical and emotional stress throughout the population due to its worldwide impact. The unknowns about the disease, the social isolation, and pregnant women's concerns regarding exposure to the COVID-19, inaccessibility to necessary care, and the possibility of harm to their fetus, may cause increased psychological distress during the perinatal period. We aimed to evaluate the association between perinatal anxiety, prenatal attachment, and maternal-infant attachment status among women with those who delivered their child in a tertiary care center with rigid hospital restrictions. Read More

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Maternal obesity-associated disruption of polarized lactate transporter MCT4 expression in human placenta.

Reprod Toxicol 2022 Jun 22;112:1-6. Epub 2022 Jun 22.

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address:

Maternal obesity is associated with an increased risk of adverse pregnancy outcomes including stillbirth, and their etiology is thought to be related to placental and fetal hypoxia. In this study, we sought to investigate the levels of lactate in maternal and umbilical cord blood, a well characterized biomarker for hypoxia, and expression of plasma membrane lactate transporter MCT1 and MCT4 in the placental syncytiotrophoblast (STB), which are responsible for lactate uptake and extrusion, respectively, from pregnant women with a diagnosis of obesity following a Cesarean delivery at term. With use of approaches including immunofluorescence staining, Western blot, RT-qPCR and ELISA, our results revealed that in controls the expression of MCT1 was equally observed between basal (fetal-facing, BM) and microvillous (maternal-facing, MVM) membrane of the STB, whereas MCT4 was predominantly expressed in the MVM but barely detected in the BM. Read More

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Impact of hypertensive disorders of pregnancy on respiratory outcomes in extremely and very preterm infants: A population-based study in Japan.

Pregnancy Hypertens 2022 Jun 17;29:54-60. Epub 2022 Jun 17.

Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan; Division of Perinatology, Center for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya, Japan.

Objectives: We aimed to evaluate the impact of hypertensive disorders of pregnancy (HDP) on short- and medium-term respiratory outcomes in extremely and very preterm infants using the Neonatal Research Network of Japan database.

Study Design: This was a population-based retrospective study of preterm infants weighing ≤ 1500 g born between 22 and 31 weeks of gestation between 2003 and 2017. After 1:1 stratification matching by four factors (maternal age, gestational age, parity, and year of delivery), a total of 5137 infants in each group (HDP and non-HDP groups) were selected. Read More

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Evaluation of placental oxygenation in fetal growth restriction using blood oxygen level-dependent magnetic resonance imaging.

Placenta 2022 Jun 18;126:40-45. Epub 2022 Jun 18.

Department of Obstetrics and Gynecology, Mie University Faculty Medicine, Mie, Japan.

Introduction: Abnormalities in placental function can lead to fetal growth restriction (FGR), but there is no consensus on their evaluation. Using blood oxygen level-dependent magnetic resonance imaging (BOLD MRI), we compared placental oxygenation between FGR cases and previously reported normal pregnancies.

Methods: Eight singleton pregnant women (>32 weeks of gestation) diagnosed with fetal growth failure during pregnancy were recruited. Read More

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The influence of blood donation before pregnancy on neonatal birth weight.

PLoS One 2022 24;17(6):e0269367. Epub 2022 Jun 24.

Department of Blood Transfusion, Ningbo Medical Center Lihuili Hospital, Ningbo University, Ningbo, China.

Objective: To evaluate the effect of blood donation before pregnancy on neonatal birth weight.

Methods: A total of 14996 women with singleton pregnancies at full-term in Ningbo Medical Center Lihuili Hospital and Ningbo Women's and Children's Hospital from November 2019 to November 2020 were enrolled in this study. Detailed records of whole blood donation before pregnancy were obtained through Alipay software. Read More

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Placental location and obstetrical-neonatal outcomes - A retrospective study.

Int J Gynaecol Obstet 2022 Jun 24. Epub 2022 Jun 24.

Helen Schneider Hospital for Women, Rabin Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.

Objective: To explore the potential association of lateral placentation with pregnancy outcome.

Methods: The database of a tertiary medical center was searched for women who gave birth to a singleton infant in 2012-2020 for whom placental location was documented during antepartum sonographic examination. Clinical data were compared between patients with a central (anterior/posterior/fundal) or lateral placenta using standard statistics. Read More

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Presepsin levels in neonatal cord blood are not influenced by maternal SARS-CoV-2 infection.

Clin Chem Lab Med 2022 Jun 24. Epub 2022 Jun 24.

Neonatology Unit, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.

Objectives: Coronavirus disease (COVID-19) can present with various symptoms and can involve multiple organs. Women infected during pregnancy have a higher incidence of obstetrical complications and infants born to "positive" mothers may get the infection with different manifestations. Presepsin seems to be a promising sepsis biomarker in adults and neonates. Read More

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