150,040 results match your criteria Pregnancy Delivery


Predictors of low birth weight and preterm birth in rural Uganda: Findings from a birth cohort study.

PLoS One 2020 13;15(7):e0235626. Epub 2020 Jul 13.

Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.

Background: Approximately 20.5 million infants were born weighing <2500 g (defined as low birthweight or LBW) in 2015, primarily in low- and middle-income countries (LMICs). Infants born LBW, including those born preterm (<37 weeks gestation), are at increased risk for numerous consequences, including neonatal mortality and morbidity as well as suboptimal health and nutritional status later in life. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235626PLOS

Extremely preterm neonates have more in meconium than very preterm neonates - the microbial colonization hypothesis.

Gut Microbes 2020 Jul 13:1-9. Epub 2020 Jul 13.

Nutrition and Metabolism, Faculdade de Ciências Médicas|NOVA Medical Schoo|, Universidade NOVA de Lisboa , Lisboa, Portugal.

Growing evidence suggests that maternal microbiota can influence the neonates' gut colonization. However, the mechanisms of vertical bacterial transmission remain poorly defined. We believed that the first colonizers of the newborn come from the mother's gut and vagina during pregnancy and that this is independent of the mode of delivery. Read More

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http://dx.doi.org/10.1080/19490976.2020.1785804DOI Listing

Maternal and neonatal outcomes following the introduction of oral hypoglycaemic agents for gestational diabetes mellitus were comparable to insulin monotherapy in two historical cohorts.

S Afr Med J 2020 Jan 29;110(2):154-158. Epub 2020 Jan 29.

South African Medical Research Council/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: Gestational diabetes mellitus (GDM), a disorder of glucose intolerance first encountered during pregnancy, has far-reaching implications for both mother and child. Insulin therapy remains the 'gold standard' of care, with oral hypoglycaemic agents (OHAs) increasingly being viewed as potential alternatives.

Objectives: To compare maternal and neonatal outcomes in two cohorts of women with GDM exposed to either insulin monotherapy or OHAs. Read More

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http://dx.doi.org/10.7196/SAMJ.2020.v110i2.14024DOI Listing
January 2020

Intimate partner violence among postpartum women at a teaching hospital in Nigeria's Federal Capital City: pattern and materno-fetal outcomes.

Ther Adv Reprod Health 2020 Jan-Dec;14:2633494120928346. Epub 2020 Jun 29.

Department of Obstetrics and Gynaecology, University of Abuja/University of Abuja Teaching Hospital, Abuja, Nigeria.

Background: Intimate partner violence is an important public health and human rights issue. Previous studies have considered intimate partner violence in pregnancy mainly among pregnant women attending antenatal clinics thereby missing out a few who may encounter this problem in late pregnancy or just before delivery. This study had the objective of ascertaining the prevalence, pattern of intimate partner violence, and associated materno-fetal outcomes. Read More

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http://dx.doi.org/10.1177/2633494120928346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328348PMC

The Effect of Antepartum Depression on the Outcomes of Pregnancy and Development of Postpartum Depression: A prospective cohort study of Omani women.

Sultan Qaboos Univ Med J 2020 May 28;20(2):e179-e186. Epub 2020 Jun 28.

Department of Family Medicine & Public Health, Sultan Qaboos University Hospital, Muscat, Oman.

Objectives: This study aimed to identify the relationship between antenatal depression and pregnancy outcomes, including the risk of developing postpartum depression in Oman.

Methods: This follow-up prospective longitudinal cohort study included pregnant women attending primary healthcare institutions in Muscat, Oman from January to November 2014. The Edinburgh Postnatal Depression Scale (EPDS) was used to screen for antenatal and postnatal depression. Read More

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http://dx.doi.org/10.18295/squmj.2020.20.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328833PMC

Study of sRAGE, HMGB1, AGE, and S100A8/A9 Concentrations in Plasma and in Serum-Extracted Extracellular Vesicles of Pregnant Women With Preterm Premature Rupture of Membranes.

Front Physiol 2020 23;11:609. Epub 2020 Jun 23.

Centre de Recherche du Centre Hospitalier Universitaire (CHU) de Québec-Université Laval, Québec City, QC, Canada.

Preterm premature rupture of membranes (PPROM), defined as rupture of fetal membranes prior to 37 weeks of gestation, complicates approximately 2-4% of pregnancies and is responsible for 40% of all spontaneous preterm births. PPROM arises from complex pathophysiological pathways with a key actor: inflammation. Sterile inflammation is a feature of senescence-associated fetal membrane maturity. Read More

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http://dx.doi.org/10.3389/fphys.2020.00609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324632PMC

Postal recruitment for genetic studies of preterm birth: A feasibility study.

Wellcome Open Res 2020 30;5:26. Epub 2020 Jun 30.

Simpson Centre for Reproductive Health, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.

Preterm birth (PTB) represents the leading cause of neonatal death. Large-scale genetic studies are necessary to determine genetic influences on PTB risk, but prospective cohort studies are expensive and time-consuming. We investigated the feasibility of retrospective recruitment of post-partum women for efficient collection of genetic samples, with self-collected saliva for DNA extraction from themselves and their babies, alongside self-recollection of pregnancy and birth details to phenotype PTB. Read More

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http://dx.doi.org/10.12688/wellcomeopenres.15207.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160603.2PMC

Factors associated with a positive childbirth experience in Brazilian women: A cross-sectional study.

Women Birth 2020 Jul 8. Epub 2020 Jul 8.

Postgraduate Programme in Epidemiology, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2400/2º andar. CEP, 90035-003, Porto Alegre, RS, Brazil. Electronic address:

Background: Having a positive childbirth experience is an increasingly valued outcome. Few studies evaluated the women's satisfaction with childbirth through face-to-face interviews out of the health service environment. The objective of this study was to identify factors associated with a higher level of satisfaction with the childbirth experience among Brazilian women. Read More

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http://dx.doi.org/10.1016/j.wombi.2020.06.003DOI Listing

Neuropathy and pregnancy: An overview.

Rev Neurol (Paris) 2020 Jul 8. Epub 2020 Jul 8.

Service de Neurologie, Hopital Nord, CHU de Saint-Etienne, 42055 Saint-Etienne cedex 02, France. Electronic address:

Peripheral nerve injuries are rare in pregnant women. Nevertheless, physiological changes linked to pregnancy may induce nerve lesion. In this review we propose to focus on peripheral nerve disorders the most frequently encountered in pregnant patients. Read More

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http://dx.doi.org/10.1016/j.neurol.2020.04.024DOI Listing

The incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesions.

Taiwan J Obstet Gynecol 2020 Jul;59(4):575-579

Department of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China. Electronic address:

Objective: To analyze the correlation between placenta related disease of pregnant women with antecedent hysteroscopic adhesiolysis due to intrauterine adhesions (IUA).

Materials And Methods: This is a single center, non-randomized, open-label, retrospective cohort Study. 74 patients who had adhesiolysis and hormone therapy for IUA and progressed into the third trimester were group A and 296 without IUA were group B. Read More

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http://dx.doi.org/10.1016/j.tjog.2020.05.018DOI Listing

Outcomes of ultrasound-indicated cerclage in twin pregnancies with a short cervical length.

Taiwan J Obstet Gynecol 2020 Jul;59(4):508-513

Department of Obstetrics and Gynecology, MacKay Memorial Hospital, Taipei, Taiwan; Department of Medicine, MacKay Medical College, New Taipei City, Taiwan. Electronic address:

Objective: To investigate the outcomes of ultrasound-indicated cerclage in dichorionic-diamniotic (DCDA) twin pregnancies with a short cervical length.

Materials And Methods: This was a retrospective cohort study of DCDA twin pregnancies with a short cervical length (≤25 mm) from January 2000 to July 2017 to compare maternal and neonatal outcomes. Additional sub-analysis was performed by dividing the patients into two subgroups by a cervical length ≤15 mm and between 16 and 25 mm. Read More

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http://dx.doi.org/10.1016/j.tjog.2020.05.007DOI Listing

Professional support during the postpartum period: primiparous mothers' views on professional services and their expectations, and barriers to utilizing professional help.

BMC Pregnancy Childbirth 2020 Jul 11;20(1):402. Epub 2020 Jul 11.

School of Nursing, Health Science Centre, Xi'an Jiaotong University, Xi'an, People's Republic of China.

Background: Primiparous mothers who lack of experience and knowledge of child caring, are usually overwhelmed by multifarious stressors and challenges. Although professional support is needed for primiparas, there is a gap between the necessary high-quality services and the currently provided poor services. This study aimed to explore Chinese primiparous mothers' views on professional services, identify barriers to utilizing professional support, and further understand mothers' expectations of and preferences for the delivery of professional services. Read More

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http://dx.doi.org/10.1186/s12884-020-03087-4DOI Listing

Smartphone-based financial incentives to promote smoking cessation during pregnancy: A pilot study.

Prev Med 2020 Jul 8:106201. Epub 2020 Jul 8.

Vermont Center on Behavior and Health, University of Vermont, Burlington, VT, USA; Departments of Psychiatry, University of Vermont, Burlington, VT, USA; Psychological Science, University of Vermont, Burlington, VT, USA.

Cigarette smoking during pregnancy increases risk for pregnancy complications, growth restriction, and other adverse health outcomes. The most effective intervention for reducing smoking during pregnancy is financial incentives contingent on biochemically-verified smoking abstinence. The present study examined the efficacy of a smartphone-based intervention whereby smoking monitoring and incentive delivery occurred remotely using a mobile app. Read More

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http://dx.doi.org/10.1016/j.ypmed.2020.106201DOI Listing

Thyroid dysfunction following pregnancy and implications for breastfeeding.

Best Pract Res Clin Endocrinol Metab 2020 Jun 20:101438. Epub 2020 Jun 20.

Division of Maternal Medicine, Center for Maternal-Fetal-Neonatal and Reproductive Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagayaku, Tokyo, 1578535, Japan. Electronic address:

Subclinical autoimmune thyroiditis exacerbates after delivery through immune rebound mechanisms and results in 5 types of thyroid dysfunction. The prevalence of postpartum thyroid dysfunction is around 5% in mothers in the general population. Typically, an exacerbation induces destructive thyrotoxicosis followed by transient hypothyroidism, known as postpartum thyroiditis. Read More

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http://dx.doi.org/10.1016/j.beem.2020.101438DOI Listing

Postpartum screening for Type 2 Diabetes Mellitus in women with Gestational Diabetes: is it really performed?

Diabetes Res Clin Pract 2020 Jul 7:108309. Epub 2020 Jul 7.

Diabetes Center - University of Pisa.

Aims: This study evaluates the adherence to postpartum type 2 diabetes mellitus (T2DM) screening in women with previous gestational diabetes (GDM) and identifies elements associated with poor attendance.

Methods: We retrospectively collected data from 650 consecutive women with GDM between 2016-2018, who should had 75g-OGTT, 4-12 weeks after delivery. Impaired glucose regulation (IGR) was defined according with ADA criteria. Read More

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http://dx.doi.org/10.1016/j.diabres.2020.108309DOI Listing

Multi-centre Spanish study found no incidences of viral transmission in infants born to mothers with COVID-19.

Acta Paediatr 2020 Jul 10. Epub 2020 Jul 10.

Department of Neonatology, Clínico San Carlos University Hospital, Madrid, Spain.

Aim: Our aim was to describe the clinical features of mothers infected with COVID-19 and examine any potential vertical mother to newborn transmission. We also assessed how effective the discharge recommendations were in preventing transmission during the first month of life.

Methods: This multicentre descriptive study involved 16 Spanish hospitals. Read More

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http://dx.doi.org/10.1111/apa.15474DOI Listing

Neonatal jaundice, attention deficit hyperactivity disorder and familial effects. A Swedish register study with sibling analysis.

Acta Paediatr 2020 Jul 10. Epub 2020 Jul 10.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Aim: Neonatal jaundice is associated with higher risk of attention deficit hyperactivity disorder (ADHD), but it is unclear if the association is influenced by genetic and other familial factors. In this large population-based study, we investigated the association between neonatal jaundice and ADHD while adjusting for familial factors.

Methods: We linked several Swedish registers to identify all singleton births without congenital malformations between 1992 and 2000 (n=814,420, including 384,290 full siblings) and followed them up until 2009. Read More

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http://dx.doi.org/10.1111/apa.15475DOI Listing

Late follicular phase progesterone elevation during ovarian stimulation is not associated with decreased implantation of chromosomally screened embryos in thaw cycles.

Hum Reprod 2020 Jul 10. Epub 2020 Jul 10.

Reproductive Medicine Associates of New York, New York, NY, USA.

Study Question: What is the impact of a late follicular phase progesterone elevation (LFPE) during controlled ovarian hyperstimulation (COH) on embryonic competence and reproductive potential in thaw cycles of preimplantation genetic testing for aneuploidy (PGT-A) screened embryos?

Summary Answer: Our study findings suggest that LFPE, utilizing a progesterone cutoff value of 2.0 ng/ml, is neither associated with impaired embryonic development, increased rate of embryonic aneuploidy, nor compromised implantation and pregnancy outcomes following a euploid frozen embryo transfer (FET) cycle.

What Is Known Already: Premature progesterone elevation during COH has been associated with lower pregnancy rates due to altered endometrial receptivity in fresh IVF cycles. Read More

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http://dx.doi.org/10.1093/humrep/deaa123DOI Listing

The stepwise development of an interactive web-based sex education programme for subfertile couples: the Pleasure & Pregnancy programme.

Hum Reprod 2020 Jul 10. Epub 2020 Jul 10.

Department of Obstetrics and Gynaecology, Center for Reproductive Medicine, Amsterdam University Medical Center (UMC), University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

Study Question: Can we develop a web-based sex education programme (programme running in a web browser) that addresses the needs of subfertile couples who are advised expectant management for at least 6 months?

Summary Answer: The 'Pleasure & Pregnancy' programme addresses couples' needs, is likely to improve couples' sexual functioning, and is subsequently hypothesised to improve the chance of natural pregnancy.

What Is Known Already: According to professional guidelines (e.g. Read More

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http://dx.doi.org/10.1093/humrep/deaa106DOI Listing

Prediction Model for Vaginal Birth After Induction of Labor in Women With Hypertensive Disorders of Pregnancy.

Obstet Gynecol 2020 Jul 9. Epub 2020 Jul 9.

Department of Obstetrics and Gynecology, Women & Infants Hospital, Warren Alpert Medical School of Brown University, and the Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.

Objective: To identify characteristics associated with vaginal delivery compared with cesarean delivery after labor induction among women with hypertensive disorders of pregnancy and to develop and validate a prediction model to assist in clinical care.

Methods: We studied a retrospective cohort of women with singleton pregnancies who had hypertensive disorders of pregnancy and who underwent induction of labor at 34 weeks of gestation or more from January 1, 2002, to March 31, 2013. Exclusion criteria included spontaneous labor, prelabor cesarean delivery, and known fetal anomalies. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003938DOI Listing

Association of Obstetric and Neonatal Outcomes With Deviation From Guidelines for Gestational Carriers.

Obstet Gynecol 2020 Jul 9. Epub 2020 Jul 9.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology & Reproductive Sciences, the Division of Medical Genetics, Department of Pediatrics, the Department of Obstetrics, Gynecology & Reproductive Sciences, and the Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, California; and the University of Utah Center for Reproductive Medicine and the Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, University of Utah Health, Salt Lake City, Utah.

Objective: To evaluate whether deviation from American Society for Reproductive Medicine (ASRM) safety guidelines for women who are gestational carriers is associated with increased risk of severe obstetric and perinatal morbidity and mortality.

Methods: This is a cross-sectional study of births from gestational carrier pregnancies in Utah from 2009 to 2018 with data collected from birth certificates. Deviations from ASRM guidelines include women aged younger than 21 years or older than 45 years, nulliparity, prior stillbirth, tobacco or percutaneous drug use, more than five prior deliveries, more than three prior cesarean deliveries, major comorbidities, and mental health conditions. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003918DOI Listing

Examining the Association of Obesity With Postpartum Tubal Ligation.

Obstet Gynecol 2020 Jul 9. Epub 2020 Jul 9.

Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Parkland Health and Hospital Systems, Dallas, Texas.

Objective: To evaluate the association of increasing body mass index (BMI) on postpartum tubal ligation safety and estimate the rates of procedure complication.

Methods: We conducted a single-institution, retrospective review. Women undergoing postpartum permanent contraception after vaginal delivery from August 2015 to March 2019 were studied. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003935DOI Listing

Acute pyelonephritis during pregnancy: a systematic review of the aetiology, timing, and reported adverse perinatal risks during pregnancy.

J Obstet Gynaecol 2020 Aug 5;40(6):739-748. Epub 2019 Sep 5.

Department of Obstetrics and Gynecology, University of South Alabama, Mobile, Canada.

We performed a comprehensive systematic review of acute pyelonephritis in pregnancy using PubMed, SCOPUS, ClinicalTrials.gov, and Ovid from inception to April 2018. About 7796 references were screened for inclusion, and 52 references from 1908 to 2017 were included. Read More

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http://dx.doi.org/10.1080/01443615.2019.1647524DOI Listing

Parenting problems postpartum can be detected early in pregnancy in patients with rheumatoid arthritis.

RMD Open 2020 07;6(2)

Rheumatology, Erasmus MC, Rotterdam, Netherlands.

Objective: To describe parenting disability postpartum in patients with rheumatoid arthritis (RA) using the Parenting Disability Index and to determine early in pregnancy which patients will face parenting problems postpartum.

Methods: Data were collected from a prospective study on pregnancy and RA (Pregnancy induced Amelioration of Rheumatoid Arthritis study). Postpartum visits were performed at 6, 12 and 26 weeks after delivery. Read More

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http://dx.doi.org/10.1136/rmdopen-2020-001276DOI Listing

[Infection by SARS-CoV-2 in pregnancy and possibility of transmission to neonates: A systematic revision].

Semergen 2020 Jun 23. Epub 2020 Jun 23.

Universidad de Cantabria - IDIVAL, Santander, España; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, España. Electronic address:

Studies published on COVID-19, pregnancy and neonate disease until 30 April 2020 are revised. We found 33 articles including 553 pregnant women and 456 deliveries. The more frequent symptoms in the pregnant women were fever, cough and dyspnoea. Read More

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http://dx.doi.org/10.1016/j.semerg.2020.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309772PMC

Maternal Outcomes of Ongoing Pregnancies Complicated by Fetal Life-Limiting Conditions.

Am J Perinatol 2020 Jul 9. Epub 2020 Jul 9.

Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, Wisconsin.

Objective:  This study aimed to examine maternal outcomes of ongoing pregnancies complicated by fetal life-limiting conditions.

Study Design:  This was a retrospective matched cohort study of women with a diagnosis of fetal life-limiting condition between 2010 and 2018 in a single academic center. Cases were matched to controls (women who had normal fetal anatomic survey) according to year of delivery, body mass index, and parity in a 1:4 ratio. Read More

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http://dx.doi.org/10.1055/s-0040-1713927DOI Listing

Mediating Effects of Maternal Blood Triglycerides on the Relationship between Pre-Pregnancy Body Mass Index and Fetal Macrosomia.

J Pediatr 2020 Jul 6. Epub 2020 Jul 6.

Department of Obstetrics and Gynecology, Hangzhou Women's Hospital (Hangzhou Maternity and Child Health Care Hospital), Hangzhou, China;. Electronic address:

Objective: To examine whether the association of pre-pregnancy BMI with fetal macrosomia is mediated through maternal circulating lipids concentration during pregnancy.

Study Design: In this prospective cohort, 3011 eligible pregnant women were enrolled. Information on demographic characteristics were collected using questionnaires, and anthropometrics and laboratory tests were undertaken at 24 weeks of gestation and before delivery. Read More

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http://dx.doi.org/10.1016/j.jpeds.2020.07.011DOI Listing

Women's knowledge and its associated factors regarding optimum utilisation of antenatal care in rural Ghana: A cross-sectional study.

PLoS One 2020 9;15(7):e0234575. Epub 2020 Jul 9.

School of Public Health, University of Health and Allied Sciences, Ho, Ghana.

Introduction: Improving maternal health is a global public health challenge especially in sub-Saharan Africa. The optimum utilisation of antenatal care (ANC) by pregnant women is known to improve maternal health outcomes. Maternal morbidity and mortality rates in Ghana remain unacceptably high, particularly in rural settings where skilled delivery care often times is disproportionally low. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234575PLOS

Aggressive angiomyxoma in pregnancy: a case report and literature review.

J Int Med Res 2020 Jul;48(7):300060520936414

Department of Imaging, Fujian Maternal and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Aggressive angiomyxoma is an interstitial tumour that is often misdiagnosed and is likely to recur. There have been few reported cases of angiomyxoma in pregnant women. We report a case of a woman who was previously diagnosed with a tumour in her vulva that increased in size during both of her pregnancies and spontaneously decreased postpartum. Read More

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http://dx.doi.org/10.1177/0300060520936414DOI Listing

Increased risk of severe maternal morbidity in women with twin pregnancies resulting from oocyte donation.

Hum Reprod 2020 Jul 9. Epub 2020 Jul 9.

Centre for Epidemiology and Statistics Sorbonne Paris Cité (CRESS), Université de Paris, Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, INSERM, INRA, Paris, France.

Study Question: Is there a difference in the risk of serious maternal complications during pregnancy and the postpartum in twin pregnancies according to mode of conception: natural conception, non-IVF fertility treatment, IVF, ICSI or oocyte donation?

Summary Answer: Women with twin pregnancies after medically assisted reproduction (MAR) had an overall risk of serious maternal complications 30% higher compared with women with natural twin pregnancies, and this association varied according to the MAR procedure; the risk was increased by 50% with IVF using autologous oocytes and by 270% with oocyte donation.

What Is Known Already: IVF has been reported as a risk factor for serious maternal complications in several concordant studies of singleton pregnancies. For twin pregnancies, this association is less well documented with imprecise categorisation of the mode of conception, and results are contradictory. Read More

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http://dx.doi.org/10.1093/humrep/deaa108DOI Listing

Associations between polycystic ovary syndrome and adverse obstetric and neonatal outcomes: a population study of 9.1 million births.

Hum Reprod 2020 Jul 9. Epub 2020 Jul 9.

Department of Obstetrics and Gynecology, McGill University Health Centre, McGill University, Montreal, QC, Canada.

Study Question: Does polycystic ovary syndrome (PCOS) confer an independent risk for adverse delivery and neonatal outcomes, based on analysis of the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample (HCUP-NIS) database?

Summary Answer: After controlling for all potential confounding effects, women with PCOS are at an increased risk of experiencing preterm pre-labour rupture of membranes (PPROM), pre-term delivery (PTD), placental abruption, caesarean section (C/S) delivery, chorioamnionitis and post-partum maternal infections.

What Is Known Already: PCOS may be associated with an increased risk of adverse perinatal outcomes. However, there remain significant gaps in understanding the correlation between PCOS and important delivery and neonatal complications. Read More

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http://dx.doi.org/10.1093/humrep/deaa144DOI Listing

Safety of Pregnancy in Ventriculoperitoneal Shunt Dependent Women: Meta-analysis and Systematic Review of the Literature.

Neurol India 2020 May-Jun;68(3):548-554

Department of Neurosurgery, Khoula Hospital, Muscat, Sultanate of, Oman.

Objective: To assess the safety of pregnancy in ventriculoperitoneal (VP) shunt-dependent women.

Methods: Three electronic databases MEDLINE (PubMed), EMBASE, and the Cochrane Library were systematically searched to identify studies published in English between 1950 and 2019. We additionally searched Web of Science, Google Scholar, and ClinicalTrials. Read More

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http://dx.doi.org/10.4103/0028-3886.288995DOI Listing

Socioeconomic differences in caesarean section - are they explained by medical need? An analysis of patient record data of a large Kenyan hospital.

Int J Equity Health 2020 Jul 8;19(1):117. Epub 2020 Jul 8.

Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Background: Caesarean section (C-section) rates are often low among the poor and very high among the better-off in low- and middle-income countries. We examined to what extent these differences are explained by medical need in an African context.

Methods: We analyzed electronic records of 12,209 women who gave birth in a teaching hospital in Kenya in 2014. Read More

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http://dx.doi.org/10.1186/s12939-020-01215-2DOI Listing

Transcriptomic Modifications in Developmental Cardiopulmonary Adaptations to Chronic Hypoxia Using a Murine Model of Simulated High Altitude Exposure.

Am J Physiol Lung Cell Mol Physiol 2020 Jul 8. Epub 2020 Jul 8.

Indiana University Bloomington, United States.

Mechanisms driving adaptive developmental responses to chronic high altitude (HA) exposure are incompletely known. We developed a novel rat model mimicking the human condition of cardiopulmonary adaptation to HA starting at conception and spanning the in utero and post-natal timeframe. We assessed lung growth and cardiopulmonary structure and function, and performed transcriptome analyses to identify mechanisms facilitating developmental adaptations to chronic hypoxia. Read More

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http://dx.doi.org/10.1152/ajplung.00487.2019DOI Listing

Hypertensive Disorders of Pregnancy, Cesarean Delivery, and Severe Maternal Morbidity in an Urban Safety Net Population.

Am J Epidemiol 2020 Jul 8. Epub 2020 Jul 8.

Department of Gynecology and Obstetrics, Emory University School of Medicine.

Hypertensive disorders of pregnancy (HDP) are a leading cause of severe maternal morbidity (SMM), yet mediation by cesarean delivery is largely unexplored. We investigated the association between HDP and SMM in a cohort of deliveries at a safety net institution in Atlanta, Georgia during 2016-2018. Using multivariable generalized linear models, we estimated adjusted risk differences (aRDs), adjusted risk ratios (aRRs), and 95% confidence intervals (CIs) for the association between HDP and SMM. Read More

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http://dx.doi.org/10.1093/aje/kwaa135DOI Listing

Longitudinal continuity of care during antenatal and delivery in the Volta Region of Ghana.

Int J Gynaecol Obstet 2020 Jul 8. Epub 2020 Jul 8.

Department of Population, Family and Reproductive Health, School of Public Health, University of Ghana, Accra, Ghana.

Objective: To determine the extent of longitudinal continuity of care (CoC) during pregnancy and delivery in the Volta Region of Ghana.

Methods: Longitudinal data were used from the National Health Insurance Claims Dataset for the period January to December 2013 for pregnant women who sought antenatal and delivery care in the region. Pregnant women who delivered at a health facility with at least three visits were included in the study. Read More

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http://dx.doi.org/10.1002/ijgo.13301DOI Listing

Evaluation of the fibulin 5 gene polymorphism as a factor related to the occurrence of pelvic organ prolapse.

Rev Assoc Med Bras (1992) 2020 May 3;66(5):680-686. Epub 2020 Jul 3.

Departamento de Ginecologia e Obstetrícia, Faculdade de medicina do ABC, Santo André, SP, Brasil.

OBJECTIVE Pelvic organ prolapse (POP) is a very frequent situation in our population that may lead to a significant decrease in patients' quality of life. Currently, we are looking for predictive factors for the development of POPs; thus, this study seeks to evaluate whether the Fibulin 5 polymorphism (FBLN5) is associated with the occurrence of POP. METHODS This is a cohort study with postmenopausal women who were divided into groups by POP stage: POP stages 0 and I (control group) and POP stages III and IV (case group). Read More

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http://dx.doi.org/10.1590/1806-9282.66.5.680DOI Listing

Risk Factors for Postpartum Stress Urinary Incontinence: a Systematic Review and Meta-analysis.

Reprod Sci 2020 Jul 7. Epub 2020 Jul 7.

Department of Gynecology and Obstetrics, Women's Hospital of Nanjing Medical University Nanjing Maternity and Child Health Care Hospital Tianfei Alley, Mochou Road, Nanjing, 210004, Jiangsu Province, China.

Stress urinary incontinence (SUI) is a distressing symptom affecting females globally and is one of the most common complications of delivery. The etiology of female SUI is multifactorial, and the trauma caused by delivery is one of the most important risk factors for SUI. We performed a meta-analysis to determine the relationship between these various factors and postpartum SUI. Read More

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http://dx.doi.org/10.1007/s43032-020-00254-yDOI Listing

Risk factors for women's non-utilization of decentralized primary health care facilities for postnatal care in rural western Ethiopia.

Ther Adv Reprod Health 2020 Jan-Dec;14:2633494120928340. Epub 2020 Jun 26.

Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, USA.

Objective: Evidence suggests postnatal care contributes to reductions in maternal mortality. In Ethiopia, the proportion of women who do not utilize postnatal care after birth is high and the frequency of postnatal checks falls short of the four visits recommended by World Health Organization. This study examined risk factors associated with non-utilization of decentralized local health facilities, namely, health posts, health centers, and a primary hospital, for postnatal care services in Gida Ayana in rural western Ethiopia. Read More

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http://dx.doi.org/10.1177/2633494120928340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323273PMC

Frequency of the rs 14035 polymorphism of gen in recurrent pregnancy loss: A case-control study.

Int J Reprod Biomed (Yazd) 2020 May 31;18(5):359-366. Epub 2020 May 31.

Abortion Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Background: Genetic factors could account for recurrent pregnancy loss (RPL). The gene is a member of the "large RAS family" and a small GTPase that is essential for the translocation of Ribonucleic acid (RNA) and proteins through the nuclear pore. Mutation in the constitutive gene could stop DNA synthesis and alter the expression of genes in the uterus, likely playing a role in recurrent miscarriage. Read More

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http://dx.doi.org/10.18502/ijrm.v13i5.7156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306062PMC

Maternal and neonatal outcomes among pregnant women with different polycystic ovary syndrome phenotypes: A cross-sectional study.

Int J Reprod Biomed (Yazd) 2020 May 31;18(5):339-346. Epub 2020 May 31.

Shahid Sadougui Hospital, Shahid Sadougui University of Medical Sciences, and Health Services, Yazd, Iran.

Background: Pregnancy is a process associated with various metabolic and hormonal changes, and polycystic ovary syndrome (PCOS) can affect this process.

Objective: This study aimed to evaluate and compare the maternal and neonatal outcomes among pregnant women with different polycystic ovary syndrome phenotypes.

Materials And Methods: In this cross-sectional study, 200 pregnant women with PCOS according to the 2003 ESHRE/ASRM criteria were categorized into four phenotype groups (A-D). Read More

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http://dx.doi.org/10.18502/ijrm.v13i5.7154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306059PMC

SiPP (Stroke in Pregnancy and Postpartum): A prospective, observational, international, multicentre study on pathophysiological mechanisms, clinical profile, management and outcome of cerebrovascular diseases in pregnant and postpartum women.

Eur Stroke J 2020 Jun 6;5(2):193-203. Epub 2019 Dec 6.

Department of Clinical Sciences and Biotechnology, University of L'Aquila, L'Aquila, Italy.

Rationale: Cerebrovascular diseases associated with pregnancy and postpartum period are uncommon; however, they can have an important impact on health of both women and foetus or newborn.

Aims: To evaluate the frequency, characteristics and management of cerebrovascular events in pregnant/postpartum women, to clarify pathophysiological mechanisms underlying the occurrence of these events including biomolecular aspects, and to assess the short- and long-term cerebrovascular and global cardiovascular outcome of these patients, their predictors and infant outcome.

Methods And Design: This is an observational, prospective, multicentre, international case-control study. Read More

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http://dx.doi.org/10.1177/2396987319893512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313370PMC

Possible formation of pulmonary microthrombi in the early puerperium of pregnant women critically ill with COVID-19: Two case reports.

Case Rep Womens Health 2020 Jul 27;27:e00237. Epub 2020 Jun 27.

Hospital e Maternidade Santa Joana, Rua Dr. Eduardo Amaro 225, São Paulo, SP CEP 04104 080, Brazil.

Background: Limited data are available on the management of pregnant women with severe or critical forms of COVID-19, such as the optimal timing of provider-initiated delivery, and post-partum care, including antithrombotic prophylaxis. We present the clinical course, pre- and post-partum management, and outcomes of two pregnant women critically ill with COVID-19.

Cases: Both women had confirmed SARS-CoV-2 pneumonia with rapid clinical decompensation that required admission to the intensive care unit, intubation, and delivery by emergency cesarean section at 32 and 29 weeks. Read More

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http://dx.doi.org/10.1016/j.crwh.2020.e00237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320266PMC

Progression to Abnormal Glucose Tolerance and Its Related Risk Factors Among Women with Prior Gestational Diabetes in Rural Communities of China.

Diabetes Metab Syndr Obes 2020 29;13:2259-2268. Epub 2020 Jun 29.

School of Nursing, New York University, New York, NY, USA.

Background: The purpose of this study was to describe the status of abnormal glucose tolerance with a longer duration after delivery among women with prior gestational diabetes mellitus (GDM) in a rural community of China, and to explore the influence of socio-demographic factors, GDM-related factors (family history of diabetes, number of children, receipt of treatment for GDM), psychosocial factors (perceived stress, self-efficacy, and social support), lifestyle behaviors (physical activity, sedentary activity, fruit or vegetables intake), and obesity indicators (body mass index and waist circumferences) on abnormal glucose tolerance.

Patients And Methods: A cross-sectional descriptive survey was conducted among women with prior GDM in two county-level hospitals in Western and Eastern Hunan, China from November 2017 to June 2018. Under the guidance of life course theory, data were collected using self-report measures of socio-demographic and GDM-related factors as well as psychosocial factors (perceived stress, self-efficacy, and social support) and postpartum lifestyle behaviors (physical activity, sedentary activity, and fruit and vegetable intake). Read More

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http://dx.doi.org/10.2147/DMSO.S252542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334007PMC

Pregnancy outcomes in women with liver transplants: systematic review and meta-analysis.

HPB (Oxford) 2020 Jul 4. Epub 2020 Jul 4.

Department of Hepatobiliary, Pancreatic and Transplant Surgery, Freeman Hospital, Newcastle University NHS Foundation Trust Hospitals, Newcastle Upon Tyne, UK; Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, UK.

Background: Despite increasing reports of pregnancy in liver transplant recipients, questions remain about the impact of transplantation in pregnancy.

Methods: This systematic review was performed according to PRISMA guidelines and eligible studies were identified through a search of PubMed, Scopus and Cochrane CENTRAL databases up to 26th December 2019 for studies reporting pregnancy with liver transplant. A meta-analysis was conducted with the use of random-effects modelling and prospectively registered with the PROSPERO database. Read More

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http://dx.doi.org/10.1016/j.hpb.2020.05.001DOI Listing

Association between circulating visfatin and pre-eclampsia: a systematic review and meta-analysis.

J Matern Fetal Neonatal Med 2020 Jul 7:1-13. Epub 2020 Jul 7.

Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Objective: Pre-eclampsia (PE) is a serious pregnancy status characterized by high blood pressure. Although visfatin is usually associated with PE. Observational studies evaluating the relationship between circulating visfatin and pre-eclampsia have reported inconsistent results. Read More

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http://dx.doi.org/10.1080/14767058.2020.1789581DOI Listing