1,087 results match your criteria Practical Neurology [Journal]


Explaining dissociative seizures: a neuropsychological perspective.

Pract Neurol 2019 Feb 12. Epub 2019 Feb 12.

Department of Neurology, University Hospital of Wales, Cardiff, UK.

Dissociative seizures are common in routine neurological practice and cause considerable morbidity. However, explaining such episodes to patients is rarely straightforward. Taking a neuropsychological perspective, we present a strategy for communicating this diagnosis to both patients and families. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002100DOI Listing
February 2019

Obstetric anaesthesia: what a neurologist needs to know.

Pract Neurol 2019 Feb 12. Epub 2019 Feb 12.

Department of Neurology, Brigham and Women's Hospital, Roslindale, MA 02115, USA

Neurologists are often consulted to see women postpartum who are having difficulties involving the lower extremities; weakness, numbness and pain. Many of these women have received labour analgesia. Often, there is limited understanding by the neurologist of how these procedures are performed, why a neuraxial technique is chosen and their potential complications. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002081DOI Listing
February 2019

Multiple cerebral infarcts: a rare complication of neurosarcoidosis.

Pract Neurol 2019 Jan 30. Epub 2019 Jan 30.

Wessex Neurological Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

A 52-year-old man experienced a relapse of neurosarcoidosis, characterised by obstructive hydrocephalus and multiple posterior circulation infarcts. He was taking methotrexate, but his prednisolone was being weaned because of adverse effects. Stroke is rare in neurosarcoidosis and typically relates to granulomatous inflammation with a predilection for the perforator arteries. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002133DOI Listing
January 2019
2 Reads

Dystonic crises in dopa-responsive dystonia induced by energy drinks.

Pract Neurol 2019 Jan 30. Epub 2019 Jan 30.

Alfred Hospital, Melbourne, Victoria, Australia.

We present an interesting case of recurrent dystonic crises in dopa-responsive dystonia (DRD) likely induced by excessive consumption of aspartame-containing products, in particular sugar-free energy drinks. This has a strong practical value as acute presentations to the emergency department can be avoided in these susceptible individuals. Usual medical and dietary advice in the treatment of DRD would include the avoidance of high-dose phenylalanine-containing products, and to this we would advocate the avoidance of high-dose aspartame-containing products. Read More

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http://dx.doi.org/10.1136/practneurol-2018-001900DOI Listing
January 2019

Investigating adults with early-onset epilepsy and intellectual or physical disability.

Pract Neurol 2019 Jan 24. Epub 2019 Jan 24.

Metabolic Disease (Adult Inherited), Charles Dent Metabolic Unit, National Hospital for Neurology and Neurosurgery, London, UK.

This article focuses on investigating adults with early-onset epilepsy and intellectual or physical disability within adult neurology services. We aim to guide general neurologists in the diagnostic reassessment of people with epilepsy and complex neurological problems of unknown cause. Following an overview, we address imaging, electroencephalography, genetic studies and metabolic testing, and give examples where diagnosis directly influences treatment. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-001965
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http://dx.doi.org/10.1136/practneurol-2018-001965DOI Listing
January 2019
4 Reads

ABN News Feb 2019.

Pract Neurol 2019 02;19(1):86

Department of Neurology, University Hospitals Trust, Birmingham, UK.

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http://dx.doi.org/10.1136/practneurol-2018-002173DOI Listing
February 2019
1 Read

UK consensus on pregnancy in multiple sclerosis: 'Association of British Neurologists' guidelines.

Pract Neurol 2019 Jan 5. Epub 2019 Jan 5.

Department of Neurology, King's College Hospital NHS Foundation Trust, London, UK.

Multiple sclerosis (MS) is more common in women than men and is most commonly diagnosed in early adulthood; thus, many patients will not have completed their families at the time of diagnosis. There is increasing awareness of the importance of early treatment in preventing long-term disability in MS. Delaying treatment until women with MS have completed their families can lead to the development of irreversible disability in at least some cases. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002060DOI Listing
January 2019
1 Read

Capecitabine leukoencephalopathy.

Pract Neurol 2019 Jan 5. Epub 2019 Jan 5.

Department of Neurology, Sheffield Teaching Hospital NHS Trust, Royal Hallamshire Hospital, Sheffield, UK.

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http://dx.doi.org/10.1136/practneurol-2018-002121DOI Listing
January 2019
1 Read

Diagnosis of amyloid neuropathy.

Pract Neurol 2018 Dec 30. Epub 2018 Dec 30.

MRC Centre for Neuromuscular Diseases, Department of Neuromuscular Diseases, UCL Institute of Neurology, London, UK

Systemic amyloidosis can be hereditary or acquired. The autosomal dominant hereditary transthyretin amyloidosis and the acquired light-chain amyloidosis, the result of a plasma cell dyscrasia, are multisystem disorders with cardiovascular, autonomic and peripheral nerve involvement. There are numerous investigational modalities available to diagnose systemic amyloidosis and to assess the extent of organ involvement, but it is frequently misdiagnosed due to its heterogeneous clinical presentations and misleading investigation findings. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-002098
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http://dx.doi.org/10.1136/practneurol-2018-002098DOI Listing
December 2018
9 Reads

Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease: practical considerations.

Pract Neurol 2018 Dec 8. Epub 2018 Dec 8.

Department of Clinical Neurology, John Radcliffe University Hospital, Oxford, UK

The field of central nervous system (CNS) inflammatory diseases has recently broadened to include a new condition associated with pathogenic serum antibodies against myelin oligodendrocyte glycoprotein (MOG). This is distinct from multiple sclerosis (MS) and aquaporin-4 (AQP4) antibody neuromyelitis optica spectrum disorders (NMOSD). MOG antibody-associated disease phenotypes are varied and range from classical neuromyelitis optica to acute demyelinating encephalomyelitis and cortical encephalitis. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2017-001787
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http://dx.doi.org/10.1136/practneurol-2017-001787DOI Listing
December 2018
9 Reads

Diabetic amyotrophy: a painful radiculoplexus neuropathy.

Pract Neurol 2018 Dec 8. Epub 2018 Dec 8.

Department of Neurology, Royal Gwent Hospital, Newport, UK.

Diabetic lumbosacral radiculoplexus neuropathy is a monophasic syndrome of diffuse pain and weakness that typically affects the lower limbs asymmetrically and is often associated with significant weight loss. Recovery can be prolonged and unpredictable. It is a clinical diagnosis and investigations are performed mainly to exclude other causes. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002105DOI Listing
December 2018
3 Reads

Intracranial dural arteriovenous fistula mistaken as cervical transverse myelitis.

Pract Neurol 2018 Dec 5. Epub 2018 Dec 5.

Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK

We describe a man with an intracranial dural arteriovenous fistula that presented as a subacute longitudinally extensive cervical myelopathy. The uncommon location of the fistula and the absence of specific radiological signs resulted in initial misdiagnosis as longitudinally extensive transverse myelitis. Neurologists should have a high index of suspicion for dural arteriovenous fistula in older men, especially those with subacute or chronic symptoms, acellular cerebrospinal fluid and, particularly, if there is neurological deterioration soon after corticosteroid treatment. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002091DOI Listing
December 2018
2 Reads

Rituximab in neurological disease: principles, evidence and practice.

Pract Neurol 2019 Feb 29;19(1):5-20. Epub 2018 Nov 29.

Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK

Rituximab is a widely used B-cell-depleting monoclonal antibody. It is unlicensed for use in neurological disorders and there are no treatment guidelines. However, as a rapidly acting, targeted therapy with growing evidence of efficacy and tolerability in several neuroinflammatory disorders, it is an attractive alternative to conventional immunomodulatory medications. Read More

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http://dx.doi.org/10.1136/practneurol-2018-001899DOI Listing
February 2019
10 Reads

A pain to the patient and to the doctor.

Pract Neurol 2019 02 21;19(1):75-76. Epub 2018 Nov 21.

Department of Neurology, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.

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http://dx.doi.org/10.1136/practneurol-2018-002072DOI Listing
February 2019
1 Read

Taking the 'Disease' out of 'Parkinson's': has the disease had its day?

Authors:
Paul F Worth

Pract Neurol 2019 02 21;19(1):2-4. Epub 2018 Nov 21.

Addenbrooke's Hospital, Cambridge CB2 0QQ, UK

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http://dx.doi.org/10.1136/practneurol-2018-002066DOI Listing
February 2019
1 Read

A treatable hypertrophic neuropathy.

Pract Neurol 2019 02 17;19(1):80-82. Epub 2018 Nov 17.

Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA

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http://dx.doi.org/10.1136/practneurol-2018-002083DOI Listing
February 2019
1 Read

Malingering and factitious disorder.

Pract Neurol 2018 Nov 13. Epub 2018 Nov 13.

Nuffield Orthopaedic Hospital, Oxford Centre for Enablement, Oxford, UK.

Although exaggeration or amplification of symptoms is common in all illness, deliberate deception is rare. In settings associated with litigation/disability evaluation, the rate of malingering may be as high as 30%, but its frequency in clinical practice is not known. We describe the main characteristics of deliberate deception (factitious disorders and malingering) and ways that neurologists might detect symptom exaggeration. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-001950
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http://dx.doi.org/10.1136/practneurol-2018-001950DOI Listing
November 2018
20 Reads

Interpreting CT perfusion in stroke.

Pract Neurol 2018 Nov 13. Epub 2018 Nov 13.

Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

CT perfusion images can be rapidly obtained on all modern CT scanners and easily incorporated into an acute stroke imaging protocol. Here we discuss the technique of CT perfusion imaging, how to interpret the data and how it can contribute to the diagnosis of acute stroke and selection of patients for treatment. Many patients with acute stroke are excluded from reperfusion therapy if the onset time is not known or if they present outside of traditional treatment time windows. Read More

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http://dx.doi.org/10.1136/practneurol-2018-001917DOI Listing
November 2018
1 Read

Clinicopathological case: rapid cognitive decline and myoclonus associated with fever, arthropathy and scleritis.

Pract Neurol 2018 Nov 13. Epub 2018 Nov 13.

Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK.

A 65-year-old man presented with transient neurological symptoms, followed by rapid cognitive decline, myoclonus and fevers. He had evidence of scleritis and an arthropathy. This paper reports the clinicopathological conference discussed at the Association of British Neurologists Annual Meeting 2017. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002013DOI Listing
November 2018
8 Reads

Cataplexy.

Authors:
Paul Reading

Pract Neurol 2019 Feb 24;19(1):21-27. Epub 2018 Oct 24.

Department of Neurology, The James Cook University Hospital, Middlesbrough TS4 3BW, UK

Remarkably and almost invariably, the clinical phenomenon of cataplexy results from the loss of around 40 000 hypocretin-containing neurones in the lateral hypothalamus in the context of narcolepsy type 1. Cataplexy reflects the dysregulation of rapid-eye-movement (REM) sleep, such that REM-sleep atonia intrudes inappropriately into wakefulness as brief episodes of either focal or total paralysis of voluntary muscle. The semiology of cataplexy differs between adults and children. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002001DOI Listing
February 2019
2 Reads

Cannabis and epilepsy.

Pract Neurol 2018 Dec 18;18(6):465-471. Epub 2018 Oct 18.

School of Medicine, Discipline of Physiology, University of Dublin Trinity College, Dublin, Ireland.

Click here to listen to the Podcast The one-third of people who do not gain seizure control through current treatment options need a revolution in epilepsy therapeutics. The general population appears to be showing a fundamental and rapid shift in its opinion regarding cannabis and cannabis-related drugs. It is quite possible that cannabidiol, licensed in the USA for treating rare genetic epilepsies, may open the door for the widespread legalisation of recreational cannabis. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-002058
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http://dx.doi.org/10.1136/practneurol-2018-002058DOI Listing
December 2018
6 Reads

Cardiac cephalalgia: severe, non-exertional headache presenting as unstable angina.

Pract Neurol 2018 Oct 18. Epub 2018 Oct 18.

Department of Neurology, Gloucestershire Royal Hospital, Gloucester, UK.

Cardiac cephalalgia is a migraine-like headache that occurs during episodes of myocardial ischaemia. Clinical characteristics of the headache vary widely but are often severe in intensity, worsen with reduced myocardial perfusion and resolve with reperfusion. It can present along with typical symptoms of angina pectoris, although not always. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-002045
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http://dx.doi.org/10.1136/practneurol-2018-002045DOI Listing
October 2018
7 Reads

Long QT syndrome masquerading as epilepsy.

Pract Neurol 2019 Feb 15;19(1):56-61. Epub 2018 Oct 15.

Department of Neurology, Frimley Health NHS Foundation Trust, Frimley, UK.

The diagnosis of epilepsy is incorrect in up to 20% of cases so should be revisited if attacks are not responding to treatment. We present a case of long QT syndrome that remained undiagnosed in the epilepsy clinic for 15 years until a near-fatal arrhythmia revealed the diagnosis and allowed effective treatment of her attacks. We hope this near miss raises awareness of long QT syndrome as a potentially fatal, rare but treatable condition that neurologists must consider in people with a label of refractory epilepsy. Read More

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http://dx.doi.org/10.1136/practneurol-2018-001959DOI Listing
February 2019
2 Reads

Disseminated cerebral hydatid disease (multiple intracranial echinococcosis).

Pract Neurol 2018 Oct 10. Epub 2018 Oct 10.

Imaging Department, University College Hospital, London, UK.

Intracranial echinococcosis is relatively uncommon and usually occurs in the context of echinococcal lesions elsewhere in the body, mostly liver and lung. Multiple intracranial lesions can result from rupture of an initial single intracranial cyst (in cystic echinococcosis) or from dissemination of systemic disease of the lung, liver or heart (cystic and alveolar echinococcosis). The two main subtypes, cystic and alveolar echinococcosis, present differently and have distinct imaging features in the brain. Read More

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http://dx.doi.org/10.1136/practneurol-2018-001954DOI Listing
October 2018
3 Reads

How to do it: investigate exertional rhabdomyolysis (or not).

Pract Neurol 2019 Feb 10;19(1):43-48. Epub 2018 Oct 10.

Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK.

Rhabdomyolysis is the combination of symptoms (myalgia, weakness and muscle swelling) and a substantial rise in serum creatine kinase (CK) >50 000 IU/L; there are many causes, but here we specifically address exertional rhabdomyolysis. The consequences of this condition can be severe, including acute kidney injury and requirement for higher level care with organ support. Most patients have 'physiological' exertional rhabdomyolysis with no underlying disease; they do not need investigation and should be advised to return to normal activities in a graded fashion. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002008DOI Listing
February 2019
1 Read

Anti-NMDAR encephalitis complicating pregnancy.

Pract Neurol 2018 Oct 10. Epub 2018 Oct 10.

Department of Neurology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis was first reported in 2005 in four patients with ovarian teratomas; there have been many further cases reported since the antigen for the NMDAR antibody was confirmed in 2007. Patients characteristically have a well-defined set of features, characterised by psychiatric disturbance, seizures and cognitive disturbance, followed by movement disorders, disorders of consciousness and dysautonomia. To date, 14 cases of NMDAR encephalitis have been described in the context of pregnancy. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-002042
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http://dx.doi.org/10.1136/practneurol-2018-002042DOI Listing
October 2018
4 Reads

Lyme disease: diagnosis and management.

Pract Neurol 2018 Dec 3;18(6):455-464. Epub 2018 Oct 3.

Neurology Department, Wessex Neurosciences Centre, Southampton General Hospital, Tremona Road, Southampton, UK.

Lyme disease (borreliosis) is a tick-borne bacterial infection caused by the spirochaete , transmitted by hard-backed ticks. Actual numbers of cases are increasing and it appears that the distribution across the UK is widening; however, it occurs most frequently in area of woodland, with temperate climate. It typically presents in mid to late summer. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-001998
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http://dx.doi.org/10.1136/practneurol-2018-001998DOI Listing
December 2018
4 Reads

Can compressive thoracic cord lesions cause a pure lower motor neurone syndrome?

Pract Neurol 2019 Feb 3;19(1):72-74. Epub 2018 Oct 3.

MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK

Compressive lesions of the spinal cord usually cause a syndrome of upper motor neurone weakness, spasticity and sensory loss below the level of the lesion. It has long been recognised that compressive cervical cord lesions may present as isolated lower motor neurone weakness of the upper limbs, a syndrome termed cervical spondylotic amyotrophy. We describe two patients presenting with isolated lower motor neurone weakness of the lower limbs in association with a compressive cord lesion at T11/12, a condition we have termed thoracic spondylotic amyotrophy. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002016DOI Listing
February 2019
1 Read

Neurocysticercosis: mimics and chameleons.

Pract Neurol 2018 Oct 3. Epub 2018 Oct 3.

Neurocysticercosis Clinic, National Institute of Neurology and Neurosurgery, Mexico City, Mexico

Neurocysticercosis is the most common parasitic neurological disease worldwide, yet in Europe, it remains relatively uncommon, with many practitioners rarely seeing a case. However, immigration and international travel mean that it is becoming increasingly recognised and diagnosed in developed countries. Being a treatable condition, it is essential to be familiar with the diagnosis and to appreciate its mimics and breadth of its possible clinical presentations. Read More

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http://dx.doi.org/10.1136/practneurol-2017-001788DOI Listing
October 2018
13 Reads

Better quality of care equals better carbon footprint?

Authors:
Sui Hsien Wong

Pract Neurol 2018 Dec 3;18(6):522. Epub 2018 Oct 3.

Guy's and St Thomas' NHS Foundation Trust; Moorfields Eye Hospital, Great Maze Pond, London SE1 9RT, UK

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http://dx.doi.org/10.1136/practneurol-2018-002049DOI Listing
December 2018
1 Read

RT-QuIC: a new test for sporadic CJD.

Authors:
Alison J E Green

Pract Neurol 2019 Feb 3;19(1):49-55. Epub 2018 Oct 3.

Centre for Clinical Brain Sciences, The National CJD Research & Surveillance Unit, University of Edinburgh, Edinburgh, UK

The diagnosis of sporadic Creutzfeldt-Jakob disease (CJD) can be difficult, but the real-time quaking-induced conversion (RT-QuIC) assays have made a considerable impact on its clinical diagnosis. This technique exploits the ability of the misfolded pathological form of prion protein (PrP) found in cerebrospinal fluid (CSF) to induce conversion of normal PrP to the misfolded form, which subsequently aggregates. The formation of these aggregates of misfolded PrP is monitored in real time using fluorescent dyes. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-001935
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http://dx.doi.org/10.1136/practneurol-2018-001935DOI Listing
February 2019
14 Reads

New MS diagnostic criteria in practice.

Pract Neurol 2019 02 22;19(1):64-67. Epub 2018 Sep 22.

Queen Square Multiple Sclerosis Centre, UCL Institute of Neurology, Faculty of Brain Sciences, UCL, London, UK

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http://dx.doi.org/10.1136/practneurol-2018-001945DOI Listing
February 2019
2 Reads

Disseminated nocardiosis with cerebral and subcutaneous lesions on low-dose prednisone.

Authors:
Kedar R Mahajan

Pract Neurol 2019 Feb 21;19(1):62-63. Epub 2018 Sep 21.

Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Cleveland, OH 44195, USA

This case report is of a septuagenarian man on chronic low-dose prednisone who presented with disseminated nocardiosis () that was initially mistaken for metastatic brain cancer. Neurologists should be aware of the potential for opportunistic infections with steroid use and to consider a definite tissue diagnosis with culture and histopathology prior to treatment. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002038DOI Listing
February 2019
3 Reads

Charles Bonnet syndrome - disturbing 'playthings of the brain'.

Pract Neurol 2018 12 17;18(6):434-435. Epub 2018 Sep 17.

University of Oxford, Oxford OX3 9DU, UK

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http://dx.doi.org/10.1136/practneurol-2018-002046DOI Listing
December 2018
1 Read

The superior oblique muscle and its disorders.

Authors:
Mark Lawden

Pract Neurol 2018 10;18(5):348-349

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http://dx.doi.org/10.1136/practneurol-2018-001994DOI Listing
October 2018
1 Read

Charles Bonnet syndrome.

Authors:
Eric Nieman

Pract Neurol 2018 Dec 7;18(6):518-519. Epub 2018 Sep 7.

24 Woodside Avenue, London N6 4SS, UK.

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http://dx.doi.org/10.1136/practneurol-2018-002023DOI Listing
December 2018
2 Reads

How to do it: the clinicopathological conference.

Pract Neurol 2018 Sep 6. Epub 2018 Sep 6.

Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK

The prime purpose of the clinicopathological conference (CPC) is education, delivered ideally in an entertaining and engaging manner. This article tackles both how to organise a CPC (more challenging than it might appear) and how to survive as a CPC discussant (always challenging). The patient at the heart of the CPC will have had a challenging and difficult illness. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-001993
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http://dx.doi.org/10.1136/practneurol-2018-001993DOI Listing
September 2018
16 Reads

Hearing loss.

Pract Neurol 2019 Feb 5;19(1):28-35. Epub 2018 Sep 5.

Otology and Skull Base Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

Hearing loss affects one in six people in the UK and is a significant disease burden. In addition to communication problems, there is also an association with depression and dementia. Clinical assessment with targeted history and examination can identify the characteristics and cause of hearing loss, and complementary audiological testing can confirm its type and severity. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-001926
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http://dx.doi.org/10.1136/practneurol-2018-001926DOI Listing
February 2019
6 Reads

Repetitive compound muscle action potential: a characteristic diagnostic clue.

Pract Neurol 2019 02 5;19(1):77-79. Epub 2018 Sep 5.

Department of Clinical Neurophysiology, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-002044
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http://dx.doi.org/10.1136/practneurol-2018-002044DOI Listing
February 2019
3 Reads

Evaluation and management of adult idiopathic intracranial hypertension.

Pract Neurol 2018 Dec 28;18(6):485-488. Epub 2018 Aug 28.

Metabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.

This paper summarises the first consensus guidelines for idiopathic intracranial hypertension as an infographic. Following a systematic literature review, a multidisciplinary specialist interest group met and established questions relating to population, interventions, controls and outcomes (PICO). A survey was sent to doctors who manage idiopathic intracranial hypertension (IIH) regularly. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-002009
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http://dx.doi.org/10.1136/practneurol-2018-002009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252364PMC
December 2018
13 Reads

Periprocedural antithrombotic management for lumbar puncture: Association of British Neurologists clinical guideline.

Pract Neurol 2018 Dec 28;18(6):436-446. Epub 2018 Aug 28.

Department of Neurology, Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.

Lumbar puncture (LP) is an important and frequently performed invasive procedure for the diagnosis and management of neurological conditions. There is little in the neurological literature on the topic of periprocedural management of antithrombotics in patients undergoing LP. Current practice is therefore largely extrapolated from guidelines produced by anaesthetic bodies on neuraxial anaesthesia, haematology groups advising on periprocedural management of antiplatelet agents and anticoagulants, and by neuroradiology on imaging-guided spinal procedures. Read More

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http://dx.doi.org/10.1136/practneurol-2017-001820DOI Listing
December 2018
4 Reads

Cingulate gyrus epilepsy.

Pract Neurol 2018 Dec 12;18(6):447-454. Epub 2018 Aug 12.

Department of Neurology, King's College London, London, UK.

The cingulate gyrus is located above the corpus callosum and forms part of the limbic system. Cingulate gyrus epilepsy poses a diagnostic challenge, given its diverse and variable seizure semiology. We present two patients with seizures arising in the cingulate gyrus that highlight the electroclinical and imaging features of this rare form of epilepsy. Read More

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http://dx.doi.org/10.1136/practneurol-2017-001812DOI Listing
December 2018
5 Reads

Rheumatoid leptomeningitis presenting with an acute neuropsychiatric disorder.

Pract Neurol 2019 Feb 10;19(1):68-71. Epub 2018 Aug 10.

Department of Neurology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

Leptomeningitis is a rare central nervous system manifestation of rheumatoid arthritis, generally in patients with established chronic rheumatoid disease. We report a 41-year-old man without previous rheumatoid arthritis or psychiatric disorder who presented with an acute neuropsychiatric disturbance and polyarthralgia. His MR scan of brain showed asymmetric bifrontal leptomeningitis, confirmed on (18F)-fluoro-D-glucose-positron emission tomography. Read More

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2018-001978
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http://dx.doi.org/10.1136/practneurol-2018-001978DOI Listing
February 2019
5 Reads

Tools for your stroke team: adapting crew-resource management for acute stroke care.

Pract Neurol 2019 Feb 10;19(1):36-42. Epub 2018 Aug 10.

Department of Neurology, Goethe-University, Frankfurt am Main, Germany.

Crew-resource management is an approach to work and training that focuses on non-technical skills and strategies to prevent human error in complex procedures. It was initially termed 'cockpit-resource management' and developed for aviation in the 1970s after several severe accidents; it has contributed to a measurable increase in flight safety. In recent years, this approach has been successfully implemented in other high-reliability environments; surgical disciplines have made particular use of crew-resource management strategies and training, with resulting reduced mortality rates. Read More

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http://dx.doi.org/10.1136/practneurol-2018-001966DOI Listing
February 2019
3 Reads

Neurological manifestations of xeroderma pigmentosum due to gene mutation.

Pract Neurol 2018 12 4;18(6):489-491. Epub 2018 Aug 4.

Department of Neurology, Universidade Federal de São Paulo, Sao Paulo, Brazil.

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http://dx.doi.org/10.1136/practneurol-2018-001888DOI Listing
December 2018
7 Reads

Guillain-Barré syndrome mimicking botulism in early disease course.

Pract Neurol 2018 Dec 30;18(6):501-504. Epub 2018 Jul 30.

Department of Neurology, Mater Misericordiae University Hospital, Dublin, Ireland.

A 42-year-old man, returning to Europe after a 2-month stay in China, reported cough and runny nose. Five days later, he developed neck discomfort and rapidly evolving weakness, spreading from his arms to the facial, bulbar and neck muscles, and then the legs. He developed dysphagia and breathlessness, and was intubated in the emergency department. Read More

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http://dx.doi.org/10.1136/practneurol-2018-001891DOI Listing
December 2018
6 Reads

Weak hand and twitching legs.

Pract Neurol 2018 12 30;18(6):513-517. Epub 2018 Jul 30.

Department of Neurology, Barts Health NHS Trust, London, UK.

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http://dx.doi.org/10.1136/practneurol-2018-001948DOI Listing
December 2018
1 Read

Superior oblique myokymia.

Pract Neurol 2018 Oct 30;18(5):415-416. Epub 2018 Jul 30.

Department of Neurology, Referral Center for Autonomic Nervous System Disorders, University Hospital Center Zagreb, Zagreb, Croatia.

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http://dx.doi.org/10.1136/practneurol-2018-001967DOI Listing
October 2018
3 Reads

Acute neurology simulation training.

Pract Neurol 2018 Dec 25;18(6):477-484. Epub 2018 Jul 25.

Department of Neurology, St George's Hospital, London, UK.

Acute neurology is the neurological care that a patient receives in an emergency or urgent care situation. This can be adapted successfully to training in a simulation where learners are immersed in realistic scenarios in a safe, controlled and reproducible environment. In addition to teaching important technical skills that improve knowledge of the diagnosis and management of acute neurology, the simulation laboratory provides a valuable setting to improve human factors and non-technical skills, such as teamwork and leadership. Read More

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http://dx.doi.org/10.1136/practneurol-2017-001851DOI Listing
December 2018
3 Reads

AL amyloidosis presenting with limb girdle myopathy.

Pract Neurol 2018 Dec 24;18(6):497-500. Epub 2018 Jul 24.

Department of Neurology, Ipswich Hospital NHS Trust, Ipswich, UK.

An elderly Caucasian man presented with a 10-month history of proximal myopathy and dysphagia. His serum creatine kinase (CK) was elevated at 877 U/L (normal 40-320) and electromyography confirmed a myopathic process. Blood and urine tests suggested myeloma; bone marrow examination showed 30% plasma cells and stained positive for amyloid. Read More

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http://dx.doi.org/10.1136/practneurol-2018-001995DOI Listing
December 2018
2 Reads