211,324 results match your criteria Practical Diabetology Diabetologia Praktyczna[Journal]


A photoelectrochemical sensing strategy based on single-layer MoS modified electrode for methionine detection.

J Pharm Biomed Anal 2018 Nov 28;165:94-100. Epub 2018 Nov 28.

Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, State Key Laboratory Base of Eco-Chemical Engineering, Key Laboratory of Rubber-Plastics of Ministry of Education/Shandong Provincial Key Laboratory of Rubber Plastics, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China. Electronic address:

MoS, a typical transition metal disulfide, is widely used in the photoelectrochemical (PEC) sensor construction. In general, MoS based PEC sensor are "signal-on" strategies. Surprisingly, we discovered that the PEC response of MoS was quenched by methionine greatly. Read More

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November 2018
2 Reads

Quality improvement: A practical nursing program's admission test.

Nurse Educ Today 2018 Nov 29;73:65-70. Epub 2018 Nov 29.

Department of Child Health, School of Medicine, University of Missouri, 430 Sinclair School of Nursing, University of Missouri, Columbia, MO 65211, United States of America. Electronic address:

Introduction: Academic institutions are under pressure to maintain a nearly flawless retention rate, while graduating successful students. The use of standardized admission tests to provide data driven decisions regarding applicant selection is common. The varying reliability and validity of current standardized tests inspired a large Canadian academic institution to use a faculty developed admission test for admission to its practical nursing (PN) program. Read More

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November 2018
2 Reads

Prediction of neutrophil-to-lymphocyte ratio in the diagnosis and progression of autoimmune encephalitis.

Neurosci Lett 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurology, Shandong Provincial Hospital affiliated to Shandong University, Jing Wu Road, Huaiyin District, Jinan, 250021, Shandong, China. Electronic address:

Objective: Autoimmune encephalitis (AIE) is a group of inflammatory disorders of the brain. The severity of AIE vary among individuals and it is always a challenge to predict. In this study, we measured the neutrophil-to-lymphocyte ratio (NLR), a novel potential biomarker of inflammatory status in other inflammatory diseases, in AIE patients and evaluated NLR as a biomarker for monitoring AIE progression. Read More

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December 2018
2 Reads

Shedding Light on the Basis Set Dependence of the Minnesota Functionals: Differences Between Plane Waves, Slater Functions and Gaussians.

J Chem Theory Comput 2018 Dec 6. Epub 2018 Dec 6.

The Minnesota family of exchange-correlation (xc) functionals are among the most popular, accurate and abundantly used functionals available to date. However, their use in plane-wave based first principles MD has been limited by their sparse availability. Here, we present an implementation of the M05, M06 and M11 families of xc functionals within a plane wave/pseudopotential framework allowing for a comprehensive analysis of their basis set dependence. Read More

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December 2018

A simple DNAzyme-based fluorescent assay for Klebsiella pneumoniae.

Chembiochem 2018 Dec 6. Epub 2018 Dec 6.

University of California Irvine, Pharmaceutical Sciences, Sue and Bill Gross Stem Cell Research Center, Edwards Lifesciences Center for Advanced Cardiovascular Technology, Biomedical Engineering, 92697, Irvine, UNITED STATES.

Pathogenic bacteria pose a serious public health threat. Rapid and cost effective detection of such bacteria remains a major challenge. Here, we present a DNAzyme-based fluorescent paper sensor for Klebsiella pneumoniae. Read More

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December 2018
2 Reads

Global Development of Anticancer Therapies for Rare Cancers, Pediatric Cancers, and Molecular Subtypes of Common Cancers.

J Glob Oncol 2018 Dec(4):1-11

H. Kim Lyerly, Duke University, Durham, NC; Jun Ren, Capital University Medical Center; Zhimin Yang, China Food and Drug Administration, Beijing, People's Republic of China; Gi Hyun Kim, Korea Ministry of Food and Drug Safety, Seoul, South Korea; Sumimasa Nagai, University of Tokyo; Sumimasa Nagai, Tomohiro Yamaguchi, and Ken Hatogai, Pharmaceuticals and Medical Devices Agency; Hiroshi Katayama, National Cancer Center Hospital, Tokyo, Japan; Silvy Da Rocha Dias, European Medicines Agency, London, United Kingdom; Daniel McManus and Kathy Soltys, Health Canada, Ottawa, Ontario, Canada; Olufumilayo Olopade, University of Chicago, Chicago, IL; Nancy Goodman, Kids V Cancer, Washington, DC; Greg Reaman, US Food and Drug Administration; Thomas Gross, US National Cancer Institute, Bethesda, MD, and Renzo Canetta, Independent Consultant.

Advances in genetic sequencing and other diagnostic technologies have enabled the use of precision medicine in clinical cancer care, as well as the development of novel therapies that are targeted to specific molecular drivers of cancer. Developing these new agents and making them accessible to patients requires global clinical studies and regulatory review and approval by different national regulatory agencies. Whereas these global trials present challenges for drug developers who conduct them and regulatory agencies who oversee them, they also raise practical issues about patients with low-frequency cancers who need these therapies. Read More

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December 2018
1 Read

Building the evidence base for dengue vector control: searching for certainty in an uncertain world.

Pathog Glob Health 2018 Dec 6:1-9. Epub 2018 Dec 6.

a Heidelberg Institute of Global Health , University of Heidelberg , Germany.

This review discusses biological and chemical methods for dengue vector control, using recently emerging summary evidence, meta-analyses and systematic reviews to conclude on practical public health recommendations for Aedes control, which is increasingly relevant in an era of widespread Chikungunya, yellow feer and Zika outbreaks. The analysis follows an a priori framework of systematic reviews by the authors on vector control methods, distinguishing vector control methods into biological, chemical and environmental methods. Findings of each published systematic review by the authors, following each individual vector control method, are summarised and compared in the discussion against the findings of existing meta-analyses covering all vector control methods. Read More

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December 2018
1 Read

Workload and Performance: Associations, Insensitivities, and Dissociations.

Hum Factors 2018 Dec 6:18720818809590. Epub 2018 Dec 6.

University of Central Florida, Orlando.

Objective:: The aim of this study was to distill and define those influences under which change in objective performance level and the linked cognitive workload reflections of subjective experience and physiological variation either associate, dissociate, or are insensitive, one to another.

Background:: Human factors/ergonomics frequently employs users' self-reports of their own conscious experience, as well as their physiological reactivity, to augment the understanding of changing performance capacity. Under some circumstances, these latter workload responses are the only available assessment information to hand. Read More

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December 2018
3 Reads

Concurrent Developmental Course of Sleep Problems and Emotional/behavioral Problems in Childhood and Adolescence as Reflected by the Dysregulation Profile.

Sleep 2018 Dec 6. Epub 2018 Dec 6.

Centre and Discipline of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, The University of Western Australia, Perth, WA, Australia.

Objectives: Longitudinal data on the course and relationship of concurrent psychopathology in youth are scarce but are of need for better practical patient care and prevention. This study explores the course of (and relationships over time) between sleep problems and concurrent dimensional difficulties relating to anxiety/depression, attention deficiency and aggressive behaviors in childhood and adolescence. The latter three may jointly form a broad syndrome, the dysregulation profile. Read More

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December 2018

Capsule Network for Protein Post-Translational Modification Site Prediction.

Bioinformatics 2018 Dec 6. Epub 2018 Dec 6.

Department of Electrical Engineering and Computer Science, and Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, USA.

Motivation: Computational methods for protein post-translational modification (PTM) site prediction provide a useful approach for studying protein functions. The prediction accuracy of the existing methods has significant room for improvement. A recent deep-learning architecture, Capsule Network (CapsNet), which can characterize the internal hierarchical representation of input data, presents a great opportunity to solve this problem, especially using small training data. Read More

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December 2018

A Practical Roadmap for Writing of Medical Scientific Publications.

J Clin Rheumatol 2018 Dec 5. Epub 2018 Dec 5.

In this article, we are providing a general description of the process of moving a research project from completion to publication; we are describing the process of assigning authors, the drafting of the manuscript, the review process, and how to respond to comments received from reviewers and editors. This roadmap is meant to stimulate the scientific productivity of junior researchers across the continent. Read More

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December 2018

Cytometric Micro-Bead Magnetic Suspension Array for High-Throughput Ultra-Sensitive Detection of Aflatoxin B1.

Anal Chem 2018 Dec 6. Epub 2018 Dec 6.

High-throughput and low-cost detection of mycotoxins in complex matrices is becoming increasingly urgent but still challenged for ultra-sensitive analyses. Here we reported a green and practical cytometric micro-bead magnetic suspension array (CBMSA) strategy for rapid and economical detection of aflatoxin B1 (AFB1) in multiple batches of lotus seeds samples. The protocol included the fabrication of the suspension array chips by immobilizing the biotin-modified bovine serum albumin-AFB1 (antigen) onto the surface of streptavidin-coated magnetic micro-beads in a multi-wells array, the indirect immuno-competition of antigen and target of AFB1 in lotus seed samples with the specific antibodies, the rapid magnetic separation regardless complex pretreatment steps, and the ultra-sensitive fluorescence detection of fluorescein isothiocyanate labeled goat anti-mouse immunoglobulin G (FITC-IgG) probes. Read More

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December 2018
2 Reads

Reduced graphene oxide wrap buffering volume expansion of MnSnO anodes for enhanced stability in lithium-ion batteries.

Dalton Trans 2018 Dec 6. Epub 2018 Dec 6.

Department of Environmental Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P.R. China.

MSnO4 (M = Mn, Zn, Co, Mg, etc.) has been widely investigated as an anode material for lithium-ion batteries in recent years, but its practical applications are limited by serious capacity loss caused by severe volume expansion during Li+ insertion/extraction. So far, hollow structures, carbon coating, and encapsulation by reduced graphene oxide have been introduced to improve the electrochemical properties of MSnO4. Read More

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December 2018

[Tips and tricks: how to do a good coronary angioplasty? Instructions for use].

G Ital Cardiol (Rome) 2018 Nov;19(11):22-32

Unità di Cardiologia interventistica, Ospedale San Raffaele, Milano.

Percutaneous coronary angioplasty celebrated its 40th anniversary and gained an established role thanks to its remarkable results. The progressive development of techniques and materials together with a better understanding about the pharmacological treatment of patients with coronary artery disease contributed to this success. Nowadays percutaneous treatments have become a valid alternative to coronary artery bypass graft surgery in many patients. Read More

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November 2018

Concurrent validity and reliability of proprietary and open-source jump mat systems for the assessment of vertical jumps in sport sciences.

Acta Bioeng Biomech 2018 ;20(4):51-57

Department of Sport Sciences, University of Alicante, Ctra. San Vicente, Alicante, Spain.

Purpose: Vertical jump tests are used to assess lower-limb power of athletes in sport sciences. Flight time measurement with jump-mat systems is the most common procedure for this purpose. The aim of this study was to analyze the concurrent validity and reliability of two proprietary systems (Globus and Axon) and an open-source system (Chronojump). Read More

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January 2018

Evaluation of the safety of users of active implantable medical devices (AIMD) in the working environment in terms of exposure to electromagnetic fields - practical approach to the requirements of European Directive 2013/35/EU.

Int J Occup Med Environ Health 2018 Nov 5. Epub 2018 Nov 5.

Central Institute for Labour Protection - National Research Institute, Warszawa, Poland (Laboratory of Electromagnetic Hazards).

Objectives: Electromagnetic fields (EMF) may cause malfunctions in electronic devices, in particular in active implantable medical devices (AIMD), along with discomfort or health hazards to users. The use of AIMD by workers is increasing (especially cardiac pacemakers, implantable cardioverter defibrillators and wearable insulin infusion pumps). Electromagnetic fields may be much stronger in the working environment than applied in basic immunity tests of AIMD (based on EN 60601- 1-2:2015 and EN 50527-1:2016). Read More

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November 2018
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Appropriate selection indices for functional traits in dairy cattle breeding schemes.

J Dairy Res 2018 Dec 6:1-6. Epub 2018 Dec 6.

Department of Animal Science,Faculty of Agricultural Sciences,University of Guilan,P.O.Box:41635-1314, Rasht,Iran.

The objective of this study was to establish different single or multiple trait selection indices to calculate genetic and economic gains by combining some production, reproduction and udder health traits in a population similar to the overall practical situation in Iran, with and without imposing restrictions on genetic change for some traits. The SelAction software was used to perform the analyses based on selection index theory through a deterministic model. Results indicated that among established indices, the index that showed the highest genetic gain for milk yield did not maximize the total genetic and economic gains. Read More

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December 2018
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Application of the Co-Agonist Concerted Transition Model to Analysis of GABAA Receptor Properties.

Curr Neuropharmacol 2018 Dec 5. Epub 2018 Dec 5.

Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO. United States.

The co-agonist concerted transition model is a simple and practical solution to analyzing various aspects of GABAA receptor function. Several model-based predictions have been verified experimentally in previous reports. We review here the practical implications of the model and demonstrate how it enables simplification of the experimental procedure and data analysis to characterize the effects of mutations or properties of novel ligands. Read More

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December 2018

Graphene interdigital electrodes for improving sensitivity in Ga2O3:Zn deep-ultraviolet photoconductive detector.

ACS Appl Mater Interfaces 2018 Dec 6. Epub 2018 Dec 6.

Graphene (Gr) has been widely used as a transparent electrode material for photodetectors due to its high conductivity and high transmittance, in recent years. However, the currently low-efficiency manipulation of Gr has hindered the arraying and practical use of such detectors. We invented a multi-step method of accurately tailoring graphene into interdigital electrodes, for fabricating a sensitive, stable deep-ultraviolet photodetector based on Zn-doped Ga2O3 films. Read More

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December 2018

Operando CatalysisReveals the Superior Cracking Activity and Stability of Hierarchical ZSM-5 for the Cracking of LDPE.

ChemSusChem 2018 Dec 5. Epub 2018 Dec 5.

Jagiellonian University in Karków, Faculty of Chemistry, 3 Ingarden Street, 30-060, Kraków, POLAND.

In this communication, a new theoretical and practical framework through Operando Catalysis to study the zeolite catalytic cracking of the low-density polyethylene as model reaction, under reaction conditions is provided. Results show that a microporous ZSM-5 gives rise to less cracking products. Hierarchical ZSM-5 zeolites are more cracking active, rendering more C2-C5 hydrocarbons, with a delayed deactivation due to the secondary porosity. Read More

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December 2018

Effect of fermentation system on the physicochemical and microbial community dynamics during enset (Ensete ventricosum) fermentation.

J Appl Microbiol 2018 Dec 5. Epub 2018 Dec 5.

KU Leuven, Campus Geel, Lab4Food, Technology Cluster Bioengineering Technology, Department of Microbial and Molecular Systems, Geel, Belgium.

Aims: The present study was conducted to assess the effect of three different fermentation systems on fermentation of enset into kocho.

Methods And Results: Nine enset plants were processed, mixed and fermented in either a pit, a bamboo basket or a Sauerkraut jar. Samples were taken on days 1, 7, 15, 31, 60 and 90. Read More

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December 2018
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Influence of dietary restriction and low-intensity exercise on weight loss and insulin sensitivity in obese equids.

J Vet Intern Med 2018 Dec 5. Epub 2018 Dec 5.

Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Werribee, Victoria, Australia.

Background: The importance of including exercise with dietary modification for the management of obese equids is not clearly understood.

Objectives: To evaluate the effect of a practical low-intensity exercise regimen, in addition to dietary restriction, on indices of insulin sensitivity (SI) and plasma adipokine concentrations in obese equids.

Animals: Twenty-four obese (body condition score [BCS] ≥ 7/9) horses and ponies. Read More

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December 2018
2 Reads

Adsorption of Tetracycline with Reduced Graphene Oxide Decorated with MnFeO Nanoparticles.

Nanoscale Res Lett 2018 Dec 5;13(1):396. Epub 2018 Dec 5.

Jiangsu Provincial Key Laboratory of Materials Cycling and Pollution Control, School of Environment, Nanjing Normal University, Nanjing, 210023, China.

Nanomaterials were widely used as efficient adsorbents for environmental remediation of tetracycline pollution. However, the separation of the adsorbents posed the challenge to their practical applications. In this study, we grew magnetic MnFeO nanoparticles on the reduced graphene oxide (rGO) to form MnFeO/rGO nanocomposite with a one-step method. Read More

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December 2018
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Precision medicine allergy immunoassay methods for assessing immunoglobulin E sensitization to aeroallergen molecules.

World J Methodol 2018 Nov 29;8(3):17-36. Epub 2018 Nov 29.

Department of Allergology, "Carol Davila" University of Medicine and Pharmacy, Bucharest 022441, Romania.

Molecular-based allergy diagnosis for the assessment of a patient immunoglobulin E (IgE) sensitization profile at the molecular level uses allergen molecules (also referred to as allergen components), which may be well-defined, highly purified, natural allergen components or recombinant allergens. Modern immunoassay methods used for the detection of specific IgE against aeroallergen components are either singleplex (such as the fluorescence enzyme immunoassay with capsulated cellulose polymer solid-phase coupled allergens, the enzyme-enhanced chemiluminescence immunoassay and the reversed enzyme allergosorbent test, with liquid-phase allergens), multiparameter (such as the line blot immunoassay for defined partial allergen diagnostics with allergen components coating membrane strips) or multiplex (such as the microarray-based immunoassay on immuno solid-phase allergen chip, and the two new multiplex nanotechnology-based immunoassays: the patient-friendly allergen nano-bead array, and the macroarray nanotechnology-based immunoassay used as a molecular allergy explorer). The precision medicine diagnostic work-up may be organized as an integrated "U-shape" approach, with a "top-down" approach (from symptoms to molecules) and a "bottom-up" approach (from molecules to clinical implications), as needed in selected patients. Read More

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November 2018

Effectiveness of implementation of "mental health nursing students' clinical competency model" on academic performance of nursing students.

F1000Res 2018 7;7:1212. Epub 2018 Aug 7.

School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, 1996835119, Iran.

Clinical nursing competence in mental health is one of the most important topics in theoretical and practical nursing training with many factors affecting it. The purpose of this study is to determine the impact of the implementation of the "mental health nursing students' clinical competence model" on nursing students' academic performance. : This study is a semi experimental following one group of student nurses. Read More

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Superbubbles revisited.

Algorithms Mol Biol 2018 1;13:16. Epub 2018 Dec 1.

1Competence Center for Scalable Data Services and Solutions Dresden/Leipzig, Universität Leipzig, Augustusplatz 12, 04107 Leipzig, Germany.

Background: Superbubbles are distinctive subgraphs in direct graphs that play an important role in assembly algorithms for high-throughput sequencing (HTS) data. Their practical importance derives from the fact they are connected to their host graph by a single entrance and a single exit vertex, thus allowing them to be handled independently. Efficient algorithms for the enumeration of superbubbles are therefore of important for the processing of HTS data. Read More

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December 2018

The plasma peptidome.

Clin Proteomics 2018 1;15:39. Epub 2018 Dec 1.

1Ryerson Analytical Biochemistry Laboratory (RABL), Department of Chemistry and Biology, Faculty of Science, Ryerson University, 350 Victoria St, Toronto, ON Canada.

Background: It may be possible to discover new diagnostic or therapeutic peptides or proteins from blood plasma using LC-ESI-MS/MS to identify, with a linear quadrupole ion trap to identify, quantify and compare the statistical distributions of peptides cleaved ex vivo from plasma samples from different clinical populations.

Methods: A systematic method for the organic fractionation of plasma peptides was applied to identify and quantify the endogenous tryptic peptides from human plasma from multiple institutions by C18 HPLC followed nano electrospray ionization and tandem mass spectrometry (LC-ESI-MS/MS) with a linear quadrupole ion trap. The endogenous tryptic peptides, or tryptic phospho peptides (i. Read More

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December 2018

Cultivating employees' communal relationship and organizational citizenship behavior through authentic leadership: studying the influence of procedural justice.

Psychol Res Behav Manag 2018 8;11:545-555. Epub 2018 Nov 8.

Department of Management, Hamdard University, Islamabad, Pakistan.

Background: Leaders play vital role in organization to accomplish organizational goals and establish healthy working environment. This study addresses the effect of authentic leadership on employees' communal relationship and organizational citizenship behavior (OCB). In addition, this research also examines how procedural justice augments the effect of authentic leadership on both aforementioned employees' behavioral outcomes. Read More

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November 2018

Potential clinical application of lncRNAs in non-small cell lung cancer.

Onco Targets Ther 2018 13;11:8045-8052. Epub 2018 Nov 13.

Department of Thoracic Surgery, Affiliated Hospital of Qingdao University, Qingdao, China,

Lung cancer has been identified as one of the most prevalent and deadly tumors worldwide. In recent years, lncRNAs have been demonstrated to play a significant role in the development of lung cancer. Specifically, lncRNAs act as a regulator of cancer-critical genes, and they regulate the biological behavior of tumors at the transcriptional and posttranscriptional levels. Read More

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November 2018

Community dynamics and sensitivity to model structure: towards a probabilistic view of process-based model predictions.

J R Soc Interface 2018 Dec 5;15(149). Epub 2018 Dec 5.

School of Biological Sciences, University of Canterbury, Christchurch 8140, New Zealand.

Statistical inference and mechanistic, process-based modelling represent two philosophically different streams of research whose primary goal is to make predictions. Here, we merge elements from both approaches to keep the theoretical power of process-based models while also considering their predictive uncertainty using Bayesian statistics. In environmental and biological sciences, the predictive uncertainty of process-based models is usually reduced to parametric uncertainty. Read More

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December 2018

Practical Implementation of a Single-Night Split-Titration Protocol With BPAP-ST and AVAPS in Patients With Neuromuscular Disease.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Study Objectives: At the sleep laboratory, noninvasive positive pressure ventilation titration protocols in patients with neuromuscular disease (NMD) are based on standard pressure cycle devices in a spontaneous/timed mode (BPAP-ST). Experience integrating protocols on average volume-assured pressure support (AVAPS) mode is limited, prompting us to develop a practical single-night titration protocol that provides information to assist clinicians and patients as they decide between BPAP-ST and AVAPS modes.

Methods: We implemented a sequential titration protocol of BPAP-ST followed by AVAPS during a single-night polysomnography study in patients with NMD and reported polysomnographic and clinical metrics. Read More

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November 2018
3.053 Impact Factor

Accrediting private providers with National Health Insurance to better serve low-income populations in Kenya and Ghana: a qualitative study.

Authors:
Lauren Suchman

Int J Equity Health 2018 Dec 5;17(1):179. Epub 2018 Dec 5.

Institute for Global Health Sciences, University of California San Francisco, San Francisco, California, USA.

Background: Small private providers in low- and middle-income countries (LMICs) are well positioned to fill gaps in services to low-income populations using Social Health Insurance (SHI) schemes. However, we know little about the practical challenges both private providers and patients face in the context of SHI that may ultimately limit access to quality services for low-income populations. In this paper, we pull together data collected from private providers, patients, and SHI officials in Kenya and Ghana to answer the question: does participation in an SHI scheme affect private providers' ability to serve poorer patient populations with quality health services?

Methods: In-depth interviews were held with 204 providers over three rounds of data collection (2013, 2015, 2017) in Kenya and Ghana. Read More

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December 2018

A statistical measure for the skewness of X chromosome inactivation based on family trios.

BMC Genet 2018 Dec 5;19(1):109. Epub 2018 Dec 5.

State Key Laboratory of Organ Failure Research, Ministry of Education and Guangdong Provincial Key Laboratory of Tropical Disease Research, Department of Biostatistics, School of Public Health, Southern Medical University, Guangzhou, China.

Background: X chromosome inactivation (XCI) is an important gene regulation mechanism in females to equalize the expression levels of X chromosome between two sexes. Generally, one of two X chromosomes in females is randomly chosen to be inactivated. Nonrandom XCI (XCI skewing) is also observed in females, which has been reported to play an important role in many X-linked diseases. Read More

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December 2018
1 Read

Lightweight Workload Fingerprinting Localization Using Affinity Propagation Clustering and Gaussian Process Regression.

Sensors (Basel) 2018 Dec 4;18(12). Epub 2018 Dec 4.

Department of Information and Communication Engineering, Chosun University, Kwangju 501-759, Korea.

Fingerprinting localization approach is widely used in indoor positioning applications owing to its high reliability. However, the learning procedure of radio signals in fingerprinting is time-consuming and labor-intensive. In this paper, an affinity propagation clustering (APC)-based fingerprinting localization system with Gaussian process regression (GPR) is presented for a practical positioning system with the reduced offline workload and low online computation cost. Read More

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December 2018

Ultrasonic Transmission Tomography Sensor Design for Bubble Identification in Gas-Liquid Bubble Column Reactors.

Sensors (Basel) 2018 Dec 4;18(12). Epub 2018 Dec 4.

School of Automation, Northwestern Polytechnical University, Xi'an 710129, China.

Scientists require methods to monitor the distribution of gas bubbles in gas-liquid bubble column reactors. One non-destructive method that can potential satisfy this requirement in industrial situations is ultrasonic transmission tomography (UTT). In this paper, an ultrasonic transmission tomography sensor is designed for measuring bubble distribution in a reactor. Read More

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December 2018

An Eight-Direction Scanning Detection Algorithm for the Mapping Robot Pathfinding in Unknown Indoor Environment.

Sensors (Basel) 2018 Dec 4;18(12). Epub 2018 Dec 4.

School of Remote Sensing & Information Engineering, Wuhan University, Wuhan 430079, China.

Aiming at the problem of how to enable the mobile robot to navigate and traverse efficiently and safely in the unknown indoor environment and map the environment, an eight-direction scanning detection (eDSD) algorithm is proposed as a new pathfinding algorithm. Firstly, we use a laser-based SLAM (Simultaneous Localization and Mapping) algorithm to perform simultaneous localization and mapping to acquire the environment information around the robot. Then, according to the proposed algorithm, the 8 certain areas around the 8 directions which are developed from the robot's center point are analyzed in order to calculate the probabilistic path vector of each area. Read More

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December 2018

Therapeutic strategies for prion disease: a practical perspective.

Curr Opin Pharmacol 2018 Nov 30;44:15-19. Epub 2018 Nov 30.

Department of Neurology, University Hospitals Cleveland Medical Center, 3619 Park East Drive, Suite 206, Beachwood, OH 44122, USA.

Human prion diseases are usually rapid neurodegenerative illnesses that are invariably fatal. Despite several clinical trials, no effective treatment has been discovered in humans. Although prior clinical trials have not been successful, they provided information that is vital for the formation of future clinical trials. Read More

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November 2018

Evaluation of imidazole and its derivative against Newcastle disease virus infection in chicken: A drug repurposing approach.

Virus Res 2018 Nov 30. Epub 2018 Nov 30.

Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, 781039, Assam, India. Electronic address:

Despite recent progress in vaccination options, Newcastle disease virus (NDV) stands a severe global epidemic and economic burden. It is difficult to control NDV with vaccination alone due to its evolving genetic variability; therefore, an effective therapeutic must target to resist its replication and further evolution. Drug repurposing is a practical and economical method to develop therapeutics against pathogenic organisms. Read More

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November 2018

Short-Term Incidence of Sequelae of HCV Infection Among Medicaid Beneficiaries in Oregon.

Public Health Rep 2018 Dec 3:33354918813552. Epub 2018 Dec 3.

1 Oregon Public Health Division, Acute and Communicable Disease Prevention, Oregon Health Authority, Portland, OR, USA.

Objectives:: Given the known high morbidity and mortality of hepatitis C virus (HCV) infection in Oregon, we sought to develop a practical method of estimating the severe sequelae of HCV infection among Medicaid beneficiaries in Oregon.

Methods:: We assembled a retrospective cohort that identified all Oregon Medicaid beneficiaries with HCV infection enrolled for at least 1 year during 2009-2013. We linked this cohort to 3 data sets to identify HCV-related deaths, cases of hepatocellular carcinoma (HCC), and first hospitalizations for advanced liver disease (ALD). Read More

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December 2018

Highly Stable and Multifunctional Aza-BODIPY-Based Phototherapeutic Agent for Anticancer Treatment.

ACS Appl Mater Interfaces 2018 Dec 3. Epub 2018 Dec 3.

Phototherapy, as an important class of noninvasive tumor treatment methods, has attracted extensive research interest. Although a large amount of the near-infrared (NIR) phototherapeutic agents have been reported, the low efficiency, complicated structures, tedious synthetic procedures, and poor photostability limit their practical applications. To solve these problems, herein, a donor-acceptor-donor (D-A-D) type organic phototherapeutic agent (B-3) based on NIR aza-boron-dipyrromethene (aza-BODIPY) dye has been constructed, which shows the enhanced photothermal conversion efficiency and high singlet oxygen generation ability by simultaneously utilizing intramolecular photoinduced electron transfer (IPET) mechanism and heavy atom effects. Read More

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December 2018

How to avoid interfering electrochemical reactions in ESI-MS analysis.

J Mass Spectrom 2018 Dec 3. Epub 2018 Dec 3.

Institute of Particle Technology, FAU Erlangen-Nurnberg, Germany.

The presence of electrochemical reactions occurring in an electrospray processes at the point where the current enters the liquid is discussed since the early 1990’s. This current transfer to the liquid requires in general oxidation or reduction of either electrolyte species in the liquid sprayed or of the electrode material in contact with the liquid. As a result new chemical species are generated. Read More

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December 2018
1 Read

Opioid analgesic use and patient-reported pain outcomes after rhinologic surgery.

Int Forum Allergy Rhinol 2018 Dec 3. Epub 2018 Dec 3.

Department of Otolaryngology-Head and Neck Surgery, Department of Anesthesiology, New York-Presbyterian Hospital-Weill Cornell Medicine, New York, NY.

Background: Opioid-based analgesics are routinely prescribed after elective rhinologic surgery. Balancing appropriate pain management while avoiding overprescription necessitates an evidence-based approach.

Methods: Patients undergoing elective rhinologic surgery, including endoscopic sinus surgery (ESS), septoplasty, or ESS with septoplasty, were prospectively enrolled. Read More

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December 2018
1 Read

Heteroatom-doped MoSe2 nanosheets with enhanced hydrogen evolution kinetics for alkaline water splitting.

Chem Asian J 2018 Dec 3. Epub 2018 Dec 3.

Institute for Superconducting and Electronic Materials, ISEM, Wollongong, 2519, Wollongong, AUSTRALIA.

Electrochemical water splitting for hydrogen generation is a vital part for the prospect of future energy system, however, the practical utilization relies on the development of highly active and earth-abundant catalysts to boost the energy conversion efficiency as well as reduce the cost. Molybdenum diselenide (MoSe2) is a promising nonprecious metal-based electrocatalyst for hydrogen evolution reaction (HER) in acidic media, but it exhibits inferior alkaline HER kinetics in great part due to the sluggish water adsorption/dissociation process. Herein, the alkaline HER kinetics of MoSe2 is substantially accelerated by heteroatom doping with transition metal ions. Read More

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December 2018
2 Reads

The Association of Coloproctology of Great Britain and Ireland consensus guidelines in surgery for inflammatory bowel disease.

Colorectal Dis 2018 Dec;20 Suppl 8:3-117

Western General Hospital, Edinburgh, UK.

Aim: There is a requirement of an expansive and up to date review of surgical management of inflammatory bowel disease (IBD) that can dovetail with the medical guidelines produced by the British Society of Gastroenterology.

Methods: Surgeons who are members of the ACPGBI with a recognised interest in IBD were invited to contribute various sections of the guidelines. They were directed to produce a procedure based document using literature searches that were systematic, comprehensible, transparent and reproducible. Read More

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December 2018

A practical general method for the preparation of long acenes.

Chemistry 2018 Dec 3. Epub 2018 Dec 3.

CNRS, Cemes, 29 Rue J. Marvig, BP 94347, 31055, Toulouse, FRANCE.

The field of long acenes, the narrowest of the zig-zag graphene nanoribbons, has been an area of significant interest in the past decade due to potential applications in organic electronics, spintronics and plasmonics. However their low solubility and high reactivity has so far hindered their preparation on large scales. We report here a concise strategy for the synthesis of higher acenes through Diels-Alder condensation of arynes with a protected tetraene ketone. Read More

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December 2018

Development and validation of a nomogram incorporating axillary lymph node ratio to predict survival in node-positive breast cancer patients after neoadjuvant chemotherapy.

Jpn J Clin Oncol 2018 Dec 1. Epub 2018 Dec 1.

Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.

Objective: Over the past decade, several studies have highlighted that axillary lymph node ratio (ratio of involved over excised axillary lymph nodes) was a superior predictor for survival outcomes compared with ypN staging. Thus, this study aimed to integrate the prognostic value of axillary lymph node ratio to improve individualized prediction of survival in node-positive breast cancer patients after neoadjuvant chemotherapy.

Methods: A clinical data of 339 node-positive breast cancer patients after neoadjuvant chemotherapy from two independent centers were retrospectively reviewed. Read More

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December 2018
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Openness to help-seeking for mental illness among Greek-Cypriots.

Health Promot Int 2018 Dec;33(6):990-998

School of Health Sciences, Neapolis University, Pafos, Cyprus, 2 Danais Avenue, Paphos, Cyprus.

The aim of this study was to test a model of people's willingness to seek help for mental illness whether currently diagnosed or not. A cross-sectional design was used to test this model in a non-clinical convenience sample of Greek-Cypriots. Participants were 196 Greek-Cypriots living in Cyprus (age M = 34. Read More

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December 2018

Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior.

J Vis Exp 2018 Nov 14(141). Epub 2018 Nov 14.

Department of Psychological and Brain Sciences, Indiana University.

Young children's visual environments are dynamic, changing moment-by-moment as children physically and visually explore spaces and objects and interact with people around them. Head-mounted eye tracking offers a unique opportunity to capture children's dynamic egocentric views and how they allocate visual attention within those views. This protocol provides guiding principles and practical recommendations for researchers using head-mounted eye trackers in both laboratory and more naturalistic settings. Read More

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November 2018

Lymphoganuloma venereum in the Western world, 15 years after its re-emergence: new perspectives and research priorities.

Curr Opin Infect Dis 2018 Nov 30. Epub 2018 Nov 30.

Department of Infectious Diseases, STI Outpatient Clinic, Public Health Service of Amsterdam.

Purpose Of Review: Lymphogranuloma venereum (LGV) is a serious sexually transmitted infection caused by Chlamydia trachomatis. If left untreated LGV can cause irreversible late sequelae. LGV is endemic among a high-risk population of men who have sex with men (MSM), and largely reported in Western metropoles. Read More

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November 2018
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Immediate effects of isometric trunk stabilization exercises with suspension device on flexion extension ratio and strength in chronic low back pain patientss.

J Back Musculoskelet Rehabil 2018 Nov 19. Epub 2018 Nov 19.

Background: Recent clinical research has supported the use of suspension devices in rehabilitation procedures both in practice and in theory. Although a longitudinal study has reported on the use of suspension devices among asymptomatic subjects, it is necessary to investigate the immediate effects of suspension exercises in patients with CLBP.

Objective: The present study aims to investigate changes in neuromuscular activation after the prescription of suspension exercises in patients with CLBP. Read More

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November 2018