5,655 results match your criteria Pott Disease Tuberculous Spondylitis


A novel fixation technique using anterior C1 screw in a pediatric solitary cervical spinal juvenile xanthogranuloma.

Eur Spine J 2019 Feb 15. Epub 2019 Feb 15.

Department of Histopathology, PGIMER, Chandigarh, India.

Purpose: Juvenile xanthogranuloma (JXG) presenting as solitary vertebral body lesion is infrequently seen and usually limited to one or two levels. We report a case of an isolated JXG with extensive cervical spinal (bony and extradural) involvement in a 6-year-old child. There was a diagnostic dilemma as the radiologic and intraoperative picture resembled tuberculosis. Read More

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http://dx.doi.org/10.1007/s00586-019-05915-4DOI Listing
February 2019

Surveillance of tuberculosis (TB) cases attributable to relapse or reinfection in London, 2002-2015.

PLoS One 2019 15;14(2):e0211972. Epub 2019 Feb 15.

Field Service, National Infection Service, Public Health England, London, United Kingdom.

Recurrence of TB in an individual can occur due to relapse of the same strain or reinfection by a different strain. The contribution of reinfection and relapse to TB incidence, and the factors associated with each are unknown. We aimed to quantify and describe cases attributable to relapse or reinfection, and identify associated risk factors in order to reduce recurrence. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211972PLOS
February 2019

Value of CT-guided Core Needle Biopsy in Diagnosing Spinal Lesions: A Comparison Study.

Orthop Surg 2019 Feb 14. Epub 2019 Feb 14.

Department of Orthopaedics, Shanghai Zhongshan Hospital, Fudan University, Shanghai, China.

Objective: A retrospective study was designed to evaluate the effectiveness of CT-guided core needle biopsy in diagnosing spinal lesions through comparison with C-arm guidance.

Methods: From April 2013 to July 2017, a total of 188 patients, who suffered from spinal lesions or had malignant tumor history with a new spinal fracture, were included in this study. There were 96 men and 92 women, with an average of 57. Read More

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http://dx.doi.org/10.1111/os.12418DOI Listing
February 2019

Clinical Spectrum of Central Nervous System Tuberculosis and the Efficacy of Revised National Tuberculosis Control Program in its Management.

J Neurosci Rural Pract 2019 Jan-Mar;10(1):71-77

Senior Clinical Scientist, Department of Clinical Research, Dr. Agarwal's Healthcare Limited, Tirunelveli, Tamil Nadu, India.

Introduction: Tuberculosis (TB) is a major global problem and poses a threat which is of considerable magnitude, with an estimated one-third of the population infected with TB bacillus.

Aim: The aim of this study is to study the treatment outcomes in patients with various forms of neurological TB treated with the standardized Revised National TB Control Program (RNTCP), directly observed treatment short-course (DOTS).

Materials And Methods: Patients diagnosed to have TBM, tuberculoma with or without spinal arachnoiditis (central nervous system tuberculosis-TB [CNS-TB]) were categorized as per the RNTCP guidelines and received DOTS Category I or Category II thrice-weekly intermittent treatment as deemed appropriate. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_163_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337963PMC
February 2019

[Clinical utility of HIV viral load assessment in cerebral spinal fluid, a case report].

Rev Chilena Infectol 2018 ;35(5):601-605

Servicio de Medicina Interna, Unidad de Infectología, Chile.

Detection of virus in cerebrospinal fluid (CSF) in HIV-infected patients with HIV viral load (VL) undetectable in plasma has been termed viral escape. These leaks may be asymptomatic from a neurological point of view, similar to plasma blips, or associated with neurological disease, with discordant VL between plasma and CSF, and may be evidence of a compartmentalization of the virus and the possibility of identifying quasispecies with mutations that confer resistance to ART. We present the case of a man with AIDS and disseminated tuberculosis who presented neurological symptomatology evidenced by headache and convulsive syndrome, who presented a discordance between plasma and CSF HIV VL; the genotypic test of the virus, obtained by lumbar puncture, identified new mutations that determined a change in ART with subsequent satisfactory evolution. Read More

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http://dx.doi.org/10.4067/s0716-10182018000500601DOI Listing
January 2018
1 Read

Challenges in diagnosis of spinal epidural abscess: A case report.

Medicine (Baltimore) 2019 Feb;98(5):e14196

Department of Orthopedics.

Rationale: Spinal epidural abscess (SEA) is a rare condition that shows a high prevalence in immunocompromised patients. The clinical presentation of SEA includes the "classic triad" of pain, fever, and neurological dysfunction. However, these nonspecific features can lead to a high rate of misdiagnosis. Read More

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http://dx.doi.org/10.1097/MD.0000000000014196DOI Listing
February 2019
1 Read

Posterior versus Anterior Approach Surgery for Thoracolumbar Spinal Tuberculosis.

J Coll Physicians Surg Pak 2019 Feb;29(2):187-188

Department of Orthopedics, The Third People's Hospital of Shenzhen City, 518112, China.

The aim of this study was to compare clinical effect of posterior approach and anterior approach surgery for patients with thoracolumbar spinal tuberculosis. It was a descriptive, analytical study carried out at the Third People's Hospital of Shenzhen City, China, from March 2012 to March 2015. A total of 84 patients with thoracolumbar spinal tuberculosis were randomly divided into group A and group B, each group having 42 patients. Read More

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http://dx.doi.org/10.29271/jcpsp.2019.02.187DOI Listing
February 2019
1 Read

Spinal Tuberculosis: A Literature Review.

JBJS Rev 2019 Jan;7(1):e9

Department of Respiratory Medicine and Infectious Diseases (V.L.C.W.) and Spinal Department (A.S.M.), Royal London Hospital, London, England.

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http://dx.doi.org/10.2106/JBJS.RVW.18.00035DOI Listing
January 2019
1 Read

Can a posterior approach effectively heal thoracic and lumbar tuberculosis? Microbiology outcomes of the operative area.

J Orthop Surg Res 2019 Jan 22;14(1):24. Epub 2019 Jan 22.

Department of Orthopedics, Southwest Hospital, The Army (Third Military) Medical University, GaoTanYan 29, Chongqing, 400038, China.

Background: There was a controversy about surgery approach of thoracic and lumbar tuberculosis (TB) treatment. The aim of this study was to compare the microbiology outcomes of the drainage liquid and the clinical outcomes of a posterior and anterior approach in the treatment of thoracic and lumbar TB.

Materials And Methods: A total of 105 patients were enrolled in this prospective study from February 2011 to September 2015. Read More

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http://dx.doi.org/10.1186/s13018-019-1063-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341735PMC
January 2019

'Need of the Hour': Early Diagnosis and Management of Multidrug Resistant Tuberculosis of the Spine: An Analysis of 30 Patients from a "High Multidrug Resistant Tuberculosis Burden" Country.

Asian Spine J 2019 Jan 24. Epub 2019 Jan 24.

Spinal Disorder Surgery Unit, Department of Orthopaedics, Christian Medical College and Hospital, Vellore, India.

Study Design: Retrospective study.

Purpose: To report the prevalence of patients with multidrug-resistant (MDR) tubercular spondylodiscitis and their outcomes. Additionally, to assess the role of the Xpert MTB/RIF assay in early detection of MDR tuberculosis. Read More

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http://dx.doi.org/10.31616/asj.2018.0073DOI Listing
January 2019
1 Read

Does Preserving or Restoring Lumbar Lordosis Have an Impact on Functional Outcomes in Tuberculosis of the Lumbosacral Region?

Spine Deform 2019 Mar;7(2):356-363

Department of Orthopaedics and Spine Surgery, Ganga Hospital, 313, Mettupalayam Road, Coimbatore 641043, India.

Study Design: Single-center retrospective cohort analysis.

Objectives: To analyze the impact of loss of global lumbar lordosis (GLL) on functional outcomes in tuberculosis of the lumbar and lumbosacral spine and to define strategies to restore or preserve the physiological lumbar lordosis.

Summary Of Background Data: In tuberculosis of lumbosacral spine, loss of lumbar lordosis (LL) leads to altered lumbosacral biomechanics. Read More

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http://dx.doi.org/10.1016/j.jspd.2018.08.005DOI Listing
March 2019
1 Read

A paleopathological approach to early human adaptation for wet-rice agriculture: The first case of Neolithic spinal tuberculosis at the Yangtze River Delta of China.

Int J Paleopathol 2019 Jan 16;24:236-244. Epub 2019 Jan 16.

Department of Archaeology, Shanghai Museum, China.

The earliest evidence of human tuberculosis can be traced to at least the early dynastic periods, when full-scaled wet-rice agriculture began or entered its early developmental stages, in circum-China countries (Japan, Korea, and Thailand). Early studies indicated that the initial spread of tuberculosis coincided with the development of wet-rice agriculture. It has been proposed that the adaptation to agriculture changed human social/living environments, coincidentally favoring survival and spread of pathogenic Mycobacterial strains that cause tuberculosis. Read More

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http://dx.doi.org/10.1016/j.ijpp.2019.01.002DOI Listing
January 2019
2 Reads

Clinical-Morphological Aspects in Spinal Tuberculosis.

Curr Health Sci J 2018 Jul-Sep;44(3):250-260. Epub 2018 Jul 15.

Doctoral School, University of Medicine and Pharmacy of Craiova, Romania.

Osteoarticular tuberculosis (OATB) Aim: The authors made a clinical morphological assessment of tissue samples from patients admitted in Surgical Departments of the Emergency County Hospital of Craiova, Romania, between 1990 and 2015, proved as presenting tuberculous lesions of the spine in the Department of Pathology of the same Hospital.

Materials And Methods: The studied material consisted of bone, joint and sometimes muscle tissue fragments resulted from biopsies or surgical excisions from 7 cases coming out of 54 patients investigated in the above-mentioned period of time, where the established histological diagnosis was tuberculosis (TB). For diagnostic confirmation, Ziehl-Neelsen staining has been used as a rule but, in some cases, immunohistochemistry was also used. Read More

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http://dx.doi.org/10.12865/CHSJ.44.03.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311224PMC
July 2018
1 Read

Spontaneous spondylodiscitis: review, incidence, management, and clinical outcome in 44 patients.

Neurosurg Focus 2019 Jan;46(1):E10

2Neurosurgery Department, Cairo University, Cairo, Egypt.

OBJECTIVESpontaneous spondylodiscitis remains uncommon but is a serious complication of the vertebral column. Risk factors include diabetes, hemodialysis, intravenous drug abuse, and chronic steroid use, and pain is the most common presenting symptom. This study aims to review the literature and report on the incidence, management, and clinical outcome of spontaneous spondylodiscitis in 44 patients. Read More

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http://dx.doi.org/10.3171/2018.10.FOCUS18463DOI Listing
January 2019
4 Reads
2.105 Impact Factor

Rapid emergence of cryptococcal fungemia, Mycobacterium chelonae vertebral osteomyelitis and gastro intestinal stromal tumor in a young HIV late presenter: a case report.

BMC Infect Dis 2018 Dec 27;18(1):693. Epub 2018 Dec 27.

Division of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.

Background: Highly active antiretroviral therapy has significantly changed the natural history of HIV infection, leading to a dramatic reduction of HIV-related morbidity and mortality. Late Presenters, Very Late Presenters and AIDS presenters still represent, also in Europe, including Italy, a huge challenge in terms of diagnostic and therapeutic management.

Case Presentation: A 35-year-old male with a history of fever and back pain. Read More

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http://dx.doi.org/10.1186/s12879-018-3573-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307234PMC
December 2018
4 Reads

One-stage posterior approach for treating multilevel noncontiguous thoracic and lumbar spinal tuberculosis.

Postgrad Med 2019 Jan 26;131(1):73-77. Epub 2018 Dec 26.

b Department of Orthopaedic , Third Affiliated Hospital of Southern Medical University , Guangzhou , PR China.

Objectives: Multilevel noncontiguous thoracic and lumbar spinal tuberculosis (MNST) is a relatively rare entity. The objective of this retrospective study was to investigate whether a technique involving a one-stage posterior debridement and decompression, combined with an intervertebral fusion and posterior instrumentation, is effective for treating MNST.

Methods: Thirteen patients, with an average age of 40. Read More

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http://dx.doi.org/10.1080/00325481.2019.1552824DOI Listing
January 2019
2 Reads
1.537 Impact Factor

Pleuropulmonary tuberculosis with spinal lesions due to metastatic malignancy differentiated definitively on imaging.

BMJ Case Rep 2018 Dec 22;11(1). Epub 2018 Dec 22.

Department of Respiratory and Sleep Medicine, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.

A healthy 31-year-old man presenting with back pain was found to have multiple spinal enhancing lesions on MRI. An incidental asymptomatic large pleural effusion was identified on investigations for the back pain and pleural and pulmonary tuberculosis (TB) was subsequently diagnosed. The radiographical features on MRI spine were not typical of spinal TB and a Ga68 DOTATATE Positron Emission Tomography (PET)/CT confirmed metastatic paraganglioma with multiple bone metastases. Read More

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http://dx.doi.org/10.1136/bcr-2018-226160DOI Listing
December 2018
2 Reads

Spinal Tuberculosis: Current Concepts.

Global Spine J 2018 Dec 13;8(4 Suppl):96S-108S. Epub 2018 Dec 13.

Ganga Hospital, Coimbatore, India.

Study Design: Review article.

Objectives: A review of literature on the epidemiology, diagnosis, and management of spinal tuberculosis (TB).

Methods: A systematic computerized literature search was performed using Cochrane Database of Systematic Reviews, EMBASE, and PubMed. Read More

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http://dx.doi.org/10.1177/2192568218769053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295815PMC
December 2018
4 Reads

Froin's syndrome associated with spinal tuberculosis.

BMJ Case Rep 2018 Dec 19;11(1). Epub 2018 Dec 19.

Oxford University Clinical Research Unit, Patan Hospital, Kathmandu, Nepal.

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http://dx.doi.org/10.1136/bcr-2018-228367DOI Listing
December 2018
2 Reads

Extrapulmonary tuberculosis: a debilitating and often neglected public health problem.

BMJ Case Rep 2018 Dec 19;11(1). Epub 2018 Dec 19.

Oxford University Clinical Research Unit, Patan Hospital, Kathmandu, Nepal.

We report a case of a 33-year-old woman from Nepal who presented to a hospital with paraplegia. She was found to have pulmonary tuberculosis (TB) with lumbar spine involvement, and bilateral psoas abscesses. She had no initial symptoms attributable to pulmonary involvement. Read More

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http://dx.doi.org/10.1136/bcr-2018-226098DOI Listing
December 2018
2 Reads

Posterolateral decompression, bone graft fusion, posterior instrumentation, and local continuous chemotherapy in the surgical treatment of thoracic spinal tuberculosis.

Medicine (Baltimore) 2018 Dec;97(51):e13822

Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi, China.

To investigate the clinical efficacy of surgical treatment for thoracic spinal tuberculosis with kyphosis deformity via posterolateral debridement, fusion, posterior instrumentation and local continuous chemotherapy. A total of 25 patients with thoracic tuberculosis received surgery by posterolateral decompression, fusion, posterior instrumentation, and postural drainage with local continuous chemotherapy between June 2009 and October 2011. The clinical outcomes was evaluated using statistical analysis about deformity correction, bone fusion, neurologic status, and the visual analog score (VAS) and erythrocyte sedimentation rate (ESR). Read More

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http://dx.doi.org/10.1097/MD.0000000000013822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320134PMC
December 2018
1 Read

Inhibition of TREM1 reduces inflammation and oxidative stress after spinal cord injury (SCI) associated with HO-1 expressions.

Biomed Pharmacother 2019 Jan 26;109:2014-2021. Epub 2018 Nov 26.

Orthopedics Department, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Pudong, Shanghai, 201399, China. Electronic address:

Spinal cord injury (SCI) is a devastating event, leading to the progression of chronic neuropathic pain syndrome. Triggering receptor expressed on myeloid cells 1 (TREM1) is an innate immune receptor expressed on neutrophils and monocytes/macrophages. TREM1 enhances inflammatory response in various models of diseases, but its significance in SCI remains unclear. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07533322183468
Publisher Site
http://dx.doi.org/10.1016/j.biopha.2018.08.159DOI Listing
January 2019
7 Reads

Prediction Algorithm of the Cat Spinal Segments Lengths and Positions in Relation to the Vertebrae.

Anat Rec (Hoboken) 2018 Dec 12. Epub 2018 Dec 12.

Pavlov Institute of Physiology, Russian Academy of Sciences, Saint-Petersburg, Russia.

Detailed knowledge of the topographic organization and precise access to the spinal cord segments is crucial for the neurosurgical manipulations as well as in vivo neurophysiological investigations of the spinal networks involved in sensorimotor and visceral functions. Because of high individual variability, accurate identification of particular portion of the lumbosacral enlargement is normally possible only during postmortem dissection. Yet, it is often necessary to determine the precise location of spinal segments prior to in vivo investigation, targeting spinal cord manipulations, neurointerface implantations, and neuronal activity recordings. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ar.24054
Publisher Site
http://dx.doi.org/10.1002/ar.24054DOI Listing
December 2018
6 Reads

Anterior versus posterior instrumentation for treatment of thoracolumbar tuberculosis : A meta-analysis.

Orthopade 2018 Dec 6. Epub 2018 Dec 6.

Department of Orthopedics, Second Hospital of Lanzhou University, 730000, Lanzhou, Gansu Province, China.

Background: To compare clinical and functional outcomes of anterior versus posterior debridement and spinal fixation for surgical treatment of thoracolumbar tuberculosis.

Methods: A computer-based online search of the Cochrane Library, PubMed, EMBase, Wanfang, VIP, and the CNKI database was performed. The methodological quality of included studies was evaluated, and data analyses were performed using RevMan 5. Read More

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http://dx.doi.org/10.1007/s00132-018-03662-wDOI Listing
December 2018
1 Read

Surgical approach and management outcomes for junction tuberculous spondylitis: a retrospective study of 77 patients.

J Orthop Surg Res 2018 Dec 6;13(1):312. Epub 2018 Dec 6.

Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Background: Junction tuberculous spondylitis involves the stress transition zone of the spine and has a high risk of progression to kyphosis or paraplegia. Problems still exist with treatment for spinal junction tuberculosis. This study investigated the surgical approach and clinical outcomes of junction spinal tuberculosis. Read More

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http://dx.doi.org/10.1186/s13018-018-1021-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282286PMC
December 2018
1 Read
1.577 Impact Factor

Paradoxical reaction in HIV-negative tuberculous meningitis patients with spinal involvement.

Int J Infect Dis 2019 Feb 4;79:104-108. Epub 2018 Dec 4.

Department of Neurology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address:

Objective: The aim of this study was to investigate the occurrence of paradoxical reaction (PR) in HIV-negative tuberculous meningitis (TBM) patients with spinal involvement, as well as its possible risk factors.

Methods: Fifty TBM patients with spinal involvement were studied retrospectively and divided into a PR group and a non-PR group according to the presence of PR. Their demographic, clinical, radiological, and laboratory data, and status at follow-up were collected and compared. Read More

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http://dx.doi.org/10.1016/j.ijid.2018.11.366DOI Listing
February 2019
11 Reads
2.330 Impact Factor

Submuscular gluteal abcess: An unusual presentation of rare sacral tuberculosis.

Int J Surg Case Rep 2019 24;54:55-59. Epub 2018 Nov 24.

Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital - Faculty of Medicine Universitas, Jl. Pangeran Diponegoro No. 71, Salemba, Central Jakarta, 10430, Indonesia. Electronic address:

Introduction: Both gluteal abscess and sacral tuberculosis are rare entities in spinal tuberculosis cases. Even in endemic country, this atypical presentation may be the cause of delayed diagnosis and treatment.

Presentation Of Case: A 51-year-old woman was admitted with painless massive lump on both of her thighs that have been enlarging for the past 6 months. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612183055
Publisher Site
http://dx.doi.org/10.1016/j.ijscr.2018.11.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280601PMC
November 2018
6 Reads

Posterior Extensive Circumferential Decompressive Reconstructive Technique in Surgical Treatment of Upper Thoracic Spine Compressive Lesions.

World Neurosurg 2018 Dec 4. Epub 2018 Dec 4.

Department of Orthopedic Surgery and Traumatology, Minia University Hospital, El-Minia; and Minia University Spine Unit, Faculty of Medicine, Minia University, Minia University Hospital, El-Minia, Egypt.

Background: Complexity in ventral surgical exposure and presence of scapula and large parascapular musculature during posterior surgery are the main obstacles in operative treatment of upper thoracic spine compressive lesions (UTSCLs), such as trauma, tuberculosis, and neoplasm. Recently, the advantages of combined ventrodorsal surgery could be successfully gained using a 1-stage posterior salvage technique with enough accessibility to all 3 spinal columns. This was a retrospective evaluation of 35 patients with UTSCLs treated by the posterior extensive circumferential decompressive reconstructive (PECDR) procedure. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.194DOI Listing
December 2018
5 Reads

Clinical effectiveness of the posterior affected-vertebrae fixation method in posterior-anterior surgery to treat thoracic spinal tuberculosis.

World Neurosurg 2018 Nov 29. Epub 2018 Nov 29.

Department of Spinal Surgery, General Hospital of Ningxia Medical University, Yinchuan, China; Shanghai Guolong hospital, Shanghai, China. Electronic address:

Objective: This retrospective comparative analysis was conducted to assess the effectiveness of affected-vertebrae fixation versus short-segment fixation to treat thoracic spinal tuberculosis.

Methods: This study included 110 patients receiving treatment for thoracic spinal tuberculosis at this hospital between January 2006 and June 2013. All cases involved the use of posterior spinal correction, posterior lateral fusion, internal fixation, anterior decompression, radical debridement, and intervertebral supporting bone grafts. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.199DOI Listing
November 2018
1 Read
2.417 Impact Factor

Single-stage anterior debridement, posterior instrumentation and global fusion in thoracic and thoracolumbar tubercular spondylodiscitis.

Musculoskelet Surg 2018 Dec 4. Epub 2018 Dec 4.

Department of Orthopaedics, Division of Spine Surgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, 576-104, Karnataka, India.

Purpose: The present study evaluated the clinical and radiological outcomes in patients with tuberculosis of the thoracic and thoracolumbar spine, treated by an operative technique in which anterior debridement with posterior instrumentation and global fusion was performed through a single-stage posterior approach.

Methods: Ninty-seven patients with spinal tuberculosis, between T1 and L1, in whom anterior debridement, bone grafting, with posterior instrumentation and fusion was performed through a single-stage posterior approach, with a minimum follow-up of 2 years, formed the basis of this study. During each follow-up, neurological recovery was assessed using modified American Spinal Injury Association grading, healing of the disease was assessed by appearance of sclerosis and interbody fusion and the degree of kyphotic deformity was analysed using the modified Konstam's angle. Read More

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http://dx.doi.org/10.1007/s12306-018-0581-5DOI Listing
December 2018
2 Reads

[Application of cortical bone trajectory screw in elderly patients with lumbar tuberculosis].

Zhongguo Gu Shang 2018 Nov;31(11):1012-1016

Department of Orthopaedics, Integrated Chinese and Western Medicine Hospital of Zhejiang Province, Hangzhou 310003, Zhejiang, China.

Objective: To explore the clinical effect of cortical bone trajectory screw technology combined with anterior mini-open debridement and prop graft for lumbar tuberculosis in elderly.

Methods: The clinical data of 22 patients with lumbar tuberculosis treated by cortical bone trajectory screw technology combined with anterior mini-open debridement and prop graft from February 2015 to December 2016 were retrospectively analyzed. There were 13 males and 9 females with an average age of (73. Read More

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http://dx.doi.org/10.3969/j.issn.1003-0034.2018.11.006DOI Listing
November 2018
14 Reads

[Treatment of senile spinal tuberculosis with posterior percutaneous pedicle screw fixation combined with local percutaneous endoscopic debridement].

Zhongguo Gu Shang 2018 Nov;31(11):1005-1011

Department of Surgery, Ningbo No.6 Hospital, Ningbo 315040, Zhejiang, China;

Objective: To explore the short-term efficacy of posterior percutaneous screw fixation combined with local percutaneous endoscopic debridement in treating senile spinal tuberculosis.

Methods: The clinical data of 19 senile patients with spinal tuberculosis underwent surgical treatment from January 2015 to September 2016 were retrospectively analyzed. There were 13 males and 6 females, aged from 60 to 73 years old with an average of (66. Read More

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http://dx.doi.org/10.3969/j.issn.1003-0034.2018.11.005DOI Listing
November 2018
2 Reads

[Feasibility study of preoperative percutaneous catheter drainage in the treatment of lumbar tuberculosis with psoas abscess].

Zhongguo Gu Shang 2018 Nov;31(11):998-1004

Department of Orthopaedics, Hospital of Integrated Traditional Chinese and Western Medicine of Zhejiang Province, Hangzhou 310003, Zhejiang, China.

Objective: To investigate the effect of preoperative percutaneous drainage in lumbar tuberculosis with psoas abscess, through compare the clinical efficacy of two different methods.

Methods: Thirty-six patients with lumbar tuberculosis complicated with psoas abscess in corresponding with the inclusion criteria were admitted in Zhejiang Province Traditional Chinese Medicine Hospital from January 2015 to January 2017. The patients were divided into group A and group B according to the different therapeutic methods. Read More

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http://dx.doi.org/10.3969/j.issn.1003-0034.2018.11.004DOI Listing
November 2018
1 Read

Effect of computer navigation-assisted minimally invasive direct lateral interbody fusion in the treatment of patients with lumbar tuberculosis: A retrospective study.

Medicine (Baltimore) 2018 Nov;97(48):e13484

Department of Spine and Jiont Surgery.

The benefits of navigation-assisted technologies are not entirely understood. Therefore, this study aimed to examine the outcomes of patients with lumbar tuberculosis who received computer navigation-assisted minimally invasive direct lateral interbody fusion (DLIF).This was a retrospective study of 33 patients with lumbar tuberculosis who underwent minimally invasive DLIF at the Department of Spine and Orthopedics of Guigang People's Hospital (Guangxi, China) between January 2015 and December 2016. Read More

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http://dx.doi.org/10.1097/MD.0000000000013484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283231PMC
November 2018
1 Read

Serious chronic disease of the cervical spine and trauma in a young female from the middle ages (Czech Republic).

Int J Paleopathol 2018 Nov 26;24:185-196. Epub 2018 Nov 26.

Centre for GeoGenetics, Natural History Museum, Øster Voldgade 5-7, 1350, Copenhagen, Denmark. Electronic address:

The skeletal remains of the young female (20-24 years) from Grave JP/106, discovered in the Southern Suburb of the Břeclav - Pohansko Stronghold (Early Middle Ages, 9th century-beginning of the 10 century, present day Czech Republic) display several noteworthy pathologies. The first is deformation of the mandible, which was most probably caused by a fracture of the ramus in combination with a subcondylar fracture. The spine of this young woman also exhibits a probable traumatic injury of the cervical spine in combination with a slowly growing structure situated inside the spinal canal, which caused deformation centered upon C7. Read More

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http://dx.doi.org/10.1016/j.ijpp.2018.11.004DOI Listing
November 2018
1 Read

Treatment of Single-Level Thoracic Tuberculosis by Percutaneous Endoscopic Débridement and Allograft via the Transforaminal Approach Combined with Percutaneous Pedicle Screw Fixation: A Multicenter Study with a Median Follow-Up of 36 Months.

World Neurosurg 2019 Feb 19;122:e1472-e1481. Epub 2018 Nov 19.

Department of Orthopaedics, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

Objective: To examine effects of percutaneous endoscopic débridement and allograft via the transforaminal approach combined with percutaneous pedicle screw fixation as treatment for single-level thoracic tuberculosis.

Methods: This multicenter retrospective analysis included 75 patients with single-level thoracic tuberculosis who underwent percutaneous endoscopic débridement and allograft via the transforaminal approach combined with percutaneous pedicle screw fixation and were followed for >36 months between January 2012 and December 2014.

Results: Follow-up was 36-48 months (average 41. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.087DOI Listing
February 2019
13 Reads

Extensive Paraspinal Tuberculosis Masquerading Malignant Tumor in an Elderly Male.

Asian J Neurosurg 2018 Oct-Dec;13(4):1202-1204

Department of Neurosurgery, Narayana Medical College Hospital, Nellore, Andhra Pradesh, India.

Paraspinal tuberculosis is an uncommon manifestation of extrapulmonary tuberculosis, and in rare cases, these lesions can mimic malignant lesions. We report a case of an elderly man where imaging showed extensive left paraspinal lesion which was mimicking malignant neoplasm. The patient underwent L3-L4 unilateral partial laminotomy, there was grayish, relatively avascular lesion in the left paraspinal region, involving the left psoas muscle and going into the neural foramina, and a subtotal resection of the lesion could be performed. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_2_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208234PMC
November 2018
12 Reads

Preliminary experience in treating thoracic spinal tuberculosis via a posterior modified transfacet debridement, instrumentation, and interbody fusion.

J Orthop Surg Res 2018 Nov 20;13(1):292. Epub 2018 Nov 20.

Department of Spine Surgery, The First Affiliated Hospital of Fujian Medical University, 20 Chazhong Road, Fuzhou City, 350005, Fujian Province, China.

Background: Posterior transfacet approach has been proved to be a safe and effective access to treat thoracic disc herniation. However, the therapeutic effect and safety of modified transfacet approach for treating thoracic spinal tuberculosis (TST) has not been reported in the clinical literature. In this study, the clinical efficacy and safety of a single-stage posterior modified transfacet debridement, posterior instrumentation, and interbody fusion for treating TST were retrospectively evaluated. Read More

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http://dx.doi.org/10.1186/s13018-018-0994-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245769PMC
November 2018
9 Reads

A comparative study to evaluate the feasibility of preoperative percutaneous catheter drainage for the treatment of lumbar spinal tuberculosis with psoas abscess.

J Orthop Surg Res 2018 Nov 19;13(1):290. Epub 2018 Nov 19.

Department of Orthopedics, Hospital of Integrated Traditional Chinese and Western medicine in Zhejiang Province, 208 Huancheng E.Rd, Hangzhou, 310003, Zhejiang Province, People's Republic of China.

Background: Spinal tuberculosis is a frequent cause of psoas abscess (PA), and PA largely negates the efficacy of antituberculosis therapy. This study aimed to investigate the clinical outcome of preoperative percutaneous catheter drainage (PCD) in patients with lumbar spinal tuberculosis and PA.

Methods: Between January 2015 and January 2017, 72 patients with lumbar spinal tuberculosis with PA were assigned to group A (preoperative PCD) and group B (n = 36 per group). Read More

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https://josr-online.biomedcentral.com/articles/10.1186/s1301
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http://dx.doi.org/10.1186/s13018-018-0993-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245803PMC
November 2018
8 Reads

Bronchial artery embolization in treatment of hemoptysis: Treatment efficacy and complications at a tertiary care chest centre.

Med J Armed Forces India 2018 Oct 28;74(4):352-357. Epub 2017 Oct 28.

Associate Professor, Dept of Community Medicine & Epidemiologist, Armed Forces Medical College, Pune 411040, India.

Background: Hemoptysis is one of the most alarming condition to both the patients suffering from it and the treating physicians. It is caused due to varied etiologies. One of the emergent and at times life-saving treatment option is by minimally invasive interventional radiological technique of Bronchial Atery Embolization (BAE). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03771237173114
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http://dx.doi.org/10.1016/j.mjafi.2017.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224689PMC
October 2018
10 Reads

Role of Frailty Scoring in the Assessment of Perioperative Mortality in Surgical Management of Tuberculous Spondylodiscitis in the Elderly.

Global Spine J 2018 Oct 12;8(7):698-702. Epub 2018 Apr 12.

Wockhardt Hospital, Mumbai, Maharashtra, India.

Study Design: Retrospective study.

Objectives: Treatment of spinal tuberculosis in the elderly involves consideration of compromised physiology, which often poses a clinical challenge to the surgeons to balance surgical safety versus deteriorating function. Frailty scoring has been reported as an effective tool to predict mortality and morbidity in cardiovascular surgery and recently in hip fractures. Read More

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http://journals.sagepub.com/doi/10.1177/2192568218764905
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http://dx.doi.org/10.1177/2192568218764905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232711PMC
October 2018
8 Reads

Tuberculosis and non-pulmonary malignancies : study of ten cases.

Tunis Med 2018 Jun;96(6):343-347

Introduction: Tuberculosis (TBC) is a major public health problem with high mortality especially in developing countries. It is associated with a higher risk of developing pulmonary and non-pulmonary malignancies including solid and hematologic cancers. Association between TBC and nonpulmonary malignancies is rarely described in the literature. Read More

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June 2018
8 Reads

Cerebral tuberculomas in a 6-year-old girl causing central diabetes insipidus.

BMJ Case Rep 2018 Nov 12;2018. Epub 2018 Nov 12.

Consultant Paediatric Infectious Diseases and Immunology, Imperial College Healthcare NHS Trust, St Mary's Hospital, London, UK.

A 6-year-old girl presented acutely with worsening frontal headaches. She had a 3-month history of lethargy, reduced appetite, weight loss, cough and intermittent fevers. A chest X-ray showed a left upper lobe consolidation, and a CT head showed multiple enhancing lesions with significant surrounding oedema in both cerebral hemispheres. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22659
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http://dx.doi.org/10.1136/bcr-2018-226590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254463PMC
November 2018
12 Reads

Surgical outcomes of infectious spondylitis after vertebroplasty, and comparisons between pyogenic and tuberculosis.

BMC Infect Dis 2018 Nov 12;18(1):555. Epub 2018 Nov 12.

Department of Orthopedics Surgery, Bone and Joint Research Center, Chang Gung Memorial Hospital, Chang Gung University, No.5, Fu-Shin Street Kweishian, Taoyuan, 333, Taiwan.

Background: Infection after vertebroplasty (VP) is a rare but serious complication. Previous literatures showed most pathogens for infection after VP were bacteria; tuberculosis (TB) induced infection after VP was extremely rare. We reported our treatment experiences of cases with infectious spondylitis after VP, and compared the differences between developed pyogenic and TB spondylitis. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3486-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233540PMC
November 2018
9 Reads

Symptomatic Tuberculous Ligamentum Flavum Cyst Treated by Full Endoscopic Resection: Review with Technical Notes.

World Neurosurg 2019 Feb 1;122:112-115. Epub 2018 Nov 1.

Department of Neurosurgery Nanoori Hospital, Gangnam, Seoul, Republic of Korea.

Background: Tuberculosis (TB) of the posterior spinal element is an uncommon condition. In a developed country its diagnosis is becoming difficult due to low incidence.

Case Description: A 60-year-old lady presented with low back pain and right leg pain for 6 months. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183243
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http://dx.doi.org/10.1016/j.wneu.2018.10.141DOI Listing
February 2019
5 Reads
2.420 Impact Factor

Spinal Tuberculosis - Directly Observed Treatment and Short Course or Daily Anti Tubercular Therapy -Are We Over Treating?

Open Orthop J 2018 28;12:380-388. Epub 2018 Sep 28.

Department of orthopaedics, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.

Study Design: Prospective randomised control trial.

Purpose: To compare the effectiveness of Directly Observed Treatment and Short Course (DOTS) and Daily Anti Tubercular Therapy (ATT) in spinal tuberculosis with no neurological deficit.

Overview Of Literature: Spinal tuberculosis is rampant in India with a major cause of morbidity and mortality. Read More

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http://dx.doi.org/10.2174/1874325001812010380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174613PMC
September 2018
2 Reads

Incidence and risk factors of neurological complications during posterior vertebral column resection to correct severe post-tubercular kyphosis with late-onset neurological deficits: case series and review of the literature.

J Orthop Surg Res 2018 Oct 26;13(1):269. Epub 2018 Oct 26.

Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Background: Severe post-tubercular kyphosis with late-onset neurological deficits is difficult to treat, with high risk of neurological complications. This study retrospectively evaluates the efficacy and safety of posterior vertebral column resection (PVCR) for treating severe post-tubercular kyphosis with late-onset neurological deficits.

Methods: From January 2012 to December 2015, 13 patients with severe post-tubercular kyphosis underwent PVCR. Read More

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http://dx.doi.org/10.1186/s13018-018-0979-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203975PMC
October 2018
1 Read
1.580 Impact Factor

The efficiency of the posterior-only approach using shaped titanium mesh cage for the surgical treatment of spine tuberculosis in children: A preliminary study.

J Orthop Surg (Hong Kong) 2018 May-Aug;26(3):2309499018806684

Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Purpose:: The study aimed to evaluate the efficiency of the posterior-only approach using shaped titanium mesh cage for surgical treatment of spinal tuberculosis (TB) in children.

Methods:: Between January 2011 and July 2013, 22 children with a single motion spinal segment involved, including 10 with thoracic, 4 with thoracolumbar, and 8 with lumbar, were enrolled in the study. The patients were treated by the posterior-only approach using the shaped titanium mesh cages. Read More

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http://dx.doi.org/10.1177/2309499018806684DOI Listing
October 2018
6 Reads

A Case of Tuberculosis Spondylodiscitis With Paraspinal Abscess in a 2-Year-Old Child.

Glob Pediatr Health 2018 15;5:2333794X18805614. Epub 2018 Oct 15.

KK Women's and Children's Hospital, Singapore, Singapore.

In this article, we report a case of tuberculosis spondylodiscitis in a 2-year-old child. Imaging of her spine showed a paraspinal abscess. The diagnosis of spinal tuberculosis remains difficult, and we discuss its salient features and current management within the pediatric population. Read More

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http://journals.sagepub.com/doi/10.1177/2333794X18805614
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http://dx.doi.org/10.1177/2333794X18805614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195007PMC
October 2018
15 Reads

Concurrent Intramedullary and Intracranial Tuberculomass.

J Assoc Physicians India 2018 Apr;66(4):72-74

Senior Resident Neurosurgery, N.S.C.B. Medical College, Jabalpur, Madhya Pradesh.

Tuberculosis of the central nervous system (CNS) is well known. CNS involvement can occur in the form of tubercular meningitis (TBM), tuberculous vasculitis, tuberculoma and rarely brain abscess. Tubercular granulomas generally solitary and occur in the brain but they may be multiple and involve other areas such as spinal cord, epidural space and subdural space also. Read More

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April 2018
11 Reads