5,909 results match your criteria Pott Disease Tuberculous Spondylitis


Change of Pyogenic and Tuberculous Spondylitis between 2007 and 2016 Year : A Nationwide Study.

J Korean Neurosurg Soc 2020 Jul 6. Epub 2020 Jul 6.

Department of Neurosurgery, Bundang CHA Medical Center, CHA University College of Medicine, Seongnam, Korea.

Objective: We attempted to compare the incidence of pyogenic spondylitis (PS) and tuberculous spondylitis (TS) between 2007 and 2016. Furthermore, we investigated the patients who underwent surgery in 2016 compared to that in 2007.

Methods: We used a nationwide database managed by the Korean National Health Insurance Service (NHIS) in 2007 and 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3340/jkns.2020.0013DOI Listing

Atypical spinal tuberculosis mimicking malignancy: the utility of multimodality imaging evaluation.

Postgrad Med J 2020 Jun 28. Epub 2020 Jun 28.

Department of Radiology, Changi General Hospital, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/postgradmedj-2020-138350DOI Listing

Collagen particle with collagen-binding bone morphogenetic protein-2 promotes vertebral laminar regeneration in infant rabbits.

Biomed Mater 2020 Jun 24. Epub 2020 Jun 24.

Chinese Academy of Sciences - Institute of Genetics and Developmental Biology, No 1 West Beichen Road, Chaoyang District, Beijing, 100101, Beijing, Beijing, CHINA.

The vertebral laminar defects caused by severe spina bifida occulta, spinal fracture, or bone tuberculosis require surgical treatment. The reconstruction of vertebral laminar defects remains challenging, especially in children. In this study, we created an animal model of vertebral laminar defects in newly weaned rabbits to evaluate the therapeutic effect of bovine bone collagen particle (BBCP) that combined with bone morphogenetic protein-2 with collagen binding domain (CBD-BMP-2). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1088/1748-605X/ab9fceDOI Listing
June 2020
3.697 Impact Factor

Extraspinal articular tuberculosis: An 11-year retrospective study of demographic features and clinical outcomes in East London.

J Infect 2020 Jun 21. Epub 2020 Jun 21.

Department of Respiratory Medicine, Royal London Hospital, Barts Health NHS Trust, London, United Kingdom; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

Objectives: To describe demographic features, clinical outcomes and diagnostic delay amongst patients with extra-spinal articular tuberculosis (TB) in a low-incidence setting.

Methods: Cases of TB treated at our institution between 2004 and 2014 were identified via the London TB register (LTBR). Demographic features of extra-spinal articular TB cases were compared to controls with TB at all other sites. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jinf.2020.06.041DOI Listing

Tuberculosis of the axial skeleton mimicking malignancy.

J R Coll Physicians Edinb 2020 Jun;50(2):168-170

Department of Rheumatology, Fortis Hospital, Sector 62, Noida, Uttar Pradesh 201301, India, Email:

Multifocal bony lesions involving vertebral bodies and cancellous bones commonly occur in metastases and haematological malignancies. However, tuberculosis being a 'great mimic', can have a similar presentation. We present a young Indian female who had bony lesions involving multiple cancellous bones, without constitutional features. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4997/JRCPE.2020.221DOI Listing

Clinical Significance of M1/M2 Macrophages and Related Cytokines in Patients with Spinal Tuberculosis.

Dis Markers 2020 20;2020:2509454. Epub 2020 May 20.

State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asian, Clinical Medical Research Institute of First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China 830011.

Background: Macrophages are important immune cells involved in () infection. To further investigate the degree of disease development in patients with spinal tuberculosis (TB), we conducted research on macrophage polarization.

Methods: Thirty-six patients with spinal TB and twenty-five healthy controls were enrolled in this study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2020/2509454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267866PMC

Minimally invasive technique for the abscess drainage in lumbosacral tuberculosis using arthroscopy sheath: A case report.

Int J Surg Case Rep 2020 May 19;72:271-276. Epub 2020 May 19.

Resident of Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Electronic address:

Introduction: Spinal tuberculosis usually affects the thoracolumbar spine, with only 2-3% involving the lumbosacral region. Lumbosacral tuberculosis can lead to the formation of a presacral abscess. For drainage of the spinal abscess, the presacral region is one of the problematic regions to perform. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijscr.2020.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305372PMC

Epidemiology of skeletal tuberculosis in Beijing, China: a 10-year retrospective analysis of data.

Eur J Clin Microbiol Infect Dis 2020 Jun 19. Epub 2020 Jun 19.

National Clinical Laboratory on Tuberculosis, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis & Thoracic Tumor Research Institute, No 9, Beiguan Street, Tongzhou District, Beijing, 101149, People's Republic of China.

Skeletal tuberculosis (STB) is one of the most common forms of extrapulmonary tuberculosis; however, limited epidemiological data are available on this public health concern worldwide, especially in developing countries. The aims of this study were to analyze the epidemiological characteristics of STB cases and to identify risk factors associated with drug resistance among STB cases in China. We included STB inpatients at Beijing Chest Hospital from January 2009 through December 2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10096-020-03924-6DOI Listing

Occurrence of multidrug-resistant tuberculous meningitis associated with injury during spinal surgery: A case report.

J Infect Public Health 2020 Jun 15. Epub 2020 Jun 15.

National Clinical Laboratory on Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis & Thoracic Tumor Research Institute, Beijing 101149, China. Electronic address:

Here we describe a case of multidrug-resistant tuberculous meningitis associated with injury inflicted during spinal surgery. A 54-year-old man was diagnosed with multidrug-resistant spinal tuberculosis (TB). Anterior debridement and fusion with posterior fusion and instrumentation were conducted to remove damaged bone and TB-associated granulomatous tissue. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jiph.2020.05.022DOI Listing

Minimally invasive spinal fusion and decompression for thoracolumbar spondylodiscitis.

J Craniovertebr Junction Spine 2020 Jan-Mar;11(1):17-21. Epub 2020 Apr 4.

Department of Neurosurgery, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.

Objective: The objective was to study the results of the treatment of thoracolumbar spondylodiscitis (SD) through minimally invasive fusion and decompression technique.

Materials And Methods: All the patients were evaluated clinically and radiologically (X-ray, magnetic resonance imaging, and computed tomography scan) along with necessary laboratory investigations. They underwent the minimally invasive spinal (MIS) decompression and fusion procedure using tubular retractor system and percutaneous transpedicular fixation done under fluoroscopy guidance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/jcvjs.JCVJS_24_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274357PMC

Minimally invasive far lateral debridement combined with posterior instrumentation for thoracic and lumbar tuberculosis without severe kyphosis.

J Orthop Surg Res 2020 Jun 16;15(1):221. Epub 2020 Jun 16.

Department of Spine Surgery, Yantai Affiliated Hospital of Binzhou Medical University, No. 717, Jinbu Street, Yantai, 264000, Shandong, China.

Background: Anti-tuberculous therapy (ATT) alone cannot easily cure spine tuberculosis (STB) though it is the most essential treatment. Many studies have confirmed the efficacy of the surgical treatment of STB through anterior, anterolateral, posterior debridement, and intervertebral fusion or combined with internal fixation. However, the conventional surgical approach requires extensive exposure of the affected areas with high rates of morbidity and mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13018-020-01703-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298961PMC

The efficacy of allograft bone using titanium mesh in the posterior-only surgical treatment of thoracic and thoracolumbar spinal tuberculosis.

BMC Surg 2020 Jun 12;20(1):133. Epub 2020 Jun 12.

Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Background: The bony fusion of allograft bone using titanium mesh in the posterior-only surgical treatment of thoracic and thoracolumbar spinal tuberculosis has not been explained in detail. We aimed to analyze the efficacy of bony fusion of allograft bone using titanium mesh in the posterior-only surgical treatment of thoracic and thoracolumbar spinal tuberculosis.

Methods: We treated 32 thoracic or thoracolumbar tuberculosis patients by one-stage posterior debridement, allograft bone graft using titanium mesh, posterior instrumentation, and fusion from May 2011 to September 2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12893-020-00793-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291568PMC

The analysis of safety and effectiveness of using allografts in the treatment of spinal tuberculosis-A multicentre retrospective study.

Turk Neurosurg 2019 Nov 8. Epub 2019 Nov 8.

Third Military Medical University, Southwest Hospital, Department of Orthopaedics, Chongqing, China.

Aim: To evaluate the clinical efficacy and fusion characteristics of allografts in spinal tuberculosis (TB).

Material And Methods: The research reviewed 1196 patients with spinal tuberculosis who received treatment at six hospitals from January 2000 to January 2016. A total of 623 patients who had spinal tuberculosis were included in the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5137/1019-5149.JTN.27503-19.3DOI Listing
November 2019

Pathologic characteristics of spinal tuberculosis: analysis of 181 cases.

Int J Clin Exp Pathol 2020 1;13(5):1253-1261. Epub 2020 May 1.

Department of Orthopedics, General Hospital of Ningxia Medical University Yinchuan 750004, Ningxia, China.

Objective: This study aimed to provide a basis for the diagnosis of spinal TB by analyzing its pathologic characteristics.

Methods: The data of 181 patients with spinal TB who underwent surgery from January 2013 to January 2019 at the General Hospital of Ningxia Medical University were retrospectively analyzed. The participants comprised 80 men and 101 women with an average age of 45. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270693PMC

Minimally invasive surgery for paravertebral or psoas abscess with spinal tuberculosis - a long-term retrospective study of 106 cases.

BMC Musculoskelet Disord 2020 Jun 6;21(1):353. Epub 2020 Jun 6.

Department of Orthopaedics, the PLA General Hospital, Beijing, 100000, China.

Background: Minimally invasive surgery (MIS) is a common treatment option for paravertebral or psoas abscesses (PAs) in patients with spinal tuberculosis (ST). However, its efficacy remains controversial. The aim of the study was to evaluate the efficacy of MIS for PA with ST combined with anti-tuberculous chemotherapy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12891-020-03344-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276089PMC

Back pain "red flags": which are most predictive of serious pathology in the Emergency Department?

Eur Spine J 2020 Jun 3. Epub 2020 Jun 3.

La Trobe Sport and Exercise Medicine Research Centre, La Trobe University, Bundoora, Melbourne, Australia.

Purpose: To determine the frequency of red flag signs and symptoms in patients presenting with back pain to the Emergency Department (ED) and association with serious pathologies and investigations performed.

Methods: This retrospective observational study evaluated consecutive patients presenting with back pain to a Melbourne ED over a 14-month period. Data regarding red flags, patient characteristics, ED-initiated investigations, and diagnoses were extracted from medical records. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00586-020-06452-1DOI Listing

Transforaminal debridement with a posterior-only approach involving placement of an interbody bone graft combined with diseased vertebral fixation for the treatment of thoracic and lumbar tuberculosis: Minimum 5-year follow-up.

Medicine (Baltimore) 2020 May;99(22):e20359

Department of Orthopedics, The Third Affiliated Hospital of Chongqing Medical University (Gener Hospital), Chongqing.

The aim of this study was to evaluate the clinical and imaging results of transforaminal debridement with a posterior-only approach involving placement of an interbody bone graft combined with diseased vertebral fixation for the treatment of thoracic and lumbar tuberculosis (TB) with a minimum 5-year follow-up.Sixty-five patients who presented with active thoracic and lumbar TB between October 2006 and August 2013 were retrospectively analyzed: 20 were thoracic TB (group A), 17 were thoracolumbar TB (group B), and 28 were lumbar TB (group C). The patient data, operating time, blood loss, Visual Analog Scale score, Oswestry Disability Index score, correction of kyphosis, recovery of neurological function, and complications were recorded and analyzed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000020359DOI Listing
May 2020
5.723 Impact Factor

Vertebral tuberculosis as a paradoxical reaction to the treatment of pulmonary and meningeal tuberculosis in an immunocompetent patient: A case report.

Medicine (Baltimore) 2020 May;99(21):e20012

School of Medicine at Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.

Introduction: Paradoxical reaction in tuberculosis (TB) is defined as the reappearance of general symptoms, aggravation of pre-existing diseases, or appearance of new lesions despite adequate anti-TB therapy. It may result from the hyperactivity of the immune response, resulting in an intense inflammation. There are few cases of vertebral TB reported as paradoxical reaction, mainly among immunocompetents patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000020012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249907PMC

Syringomyelia as a delayed complication of lumbar-sacral adhesive arachnoiditis in Pott's disease.

BMJ Case Rep 2020 May 27;13(5). Epub 2020 May 27.

Department of General Medicine, Government Medical College and Hospital, Chandigarh, India.

Syringomyelia is the development of a fluid-filled cyst (syrinx) within the spinal cord and is an extremely rare chronic manifestation of tuberculosis. The syrinx so formed may expand over time, causing compression or destruction of spinal tracts and surrounding nerve roots. Development of syringomyelia in a patient of Pott's disease is particularly infrequent. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2019-234032DOI Listing

Comparison of the Diagnostic Value of MRI and Whole Body F-FDG PET/CT in Diagnosis of Spondylodiscitis.

J Clin Med 2020 May 22;9(5). Epub 2020 May 22.

Nuclear Medicine Unit, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza Giulio Cesare, 11-70124 Bari, Italy.

Spondylodiscitis is a spine infection for which a diagnosis by a magnetic resonance imaging (MRI) is considered the most appropriate imaging technique. The aim of this study was to compare the role of an F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) and an MRI in this field. For 56 patients with suspected spondylodiscitis for whom MRI and F-FDG PET/CT were performed, we retrospectively analyzed the results. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm9051581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290470PMC

Lessons learned from 40 novel PIGA patients and a review of the literature.

Epilepsia 2020 Jun 26;61(6):1142-1155. Epub 2020 May 26.

Institute for Regional Health Services, University of Southern Denmark, Odense, Denmark.

Objective: To define the phenotypic spectrum of phosphatidylinositol glycan class A protein (PIGA)-related congenital disorder of glycosylation (PIGA-CDG) and evaluate genotype-phenotype correlations.

Methods: Our cohort encompasses 40 affected males with a pathogenic PIGA variant. We performed a detailed phenotypic assessment, and in addition, we reviewed the available clinical data of 36 previously published cases and assessed the variant pathogenicity using bioinformatical approaches. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/epi.16545DOI Listing

[One-stage transpedicular debridement, posterior internal fixation and fusion for the treatment of senile thoracolumbar tuberculosis].

Zhongguo Gu Shang 2020 May;33(5):454-8

Department of Spinal Surgery, Yijishan Hospital Affiliated to Wannan Medical College, Wuhu 241001, Anhui, China.

Objective: To evaluate the clinical outcomes of one-stage transpedicular debridement, posterior internal fixation, RBK mixed streptomycin filled bone grafting for the treatment of elderly patients with thoracolumbar tuberculosis.

Methods: The clinical data of 20 elderly patients with thoracolumbar tuberculosis underwent one stage transpedicular debridement, posterior internal fixation, OSTEOSET RBK mixed streptomycin-filled bone grafting from September 2006 to July 2017 were retrospectively analyzed. There were 12 males and 8 females, aged from 62 to 83 years with an average of (72. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12200/j.issn.1003-0034.2020.02.013DOI Listing

Extra-central nervous system tuberculosis in HIV-uninfected patients of tuberculous meningitis: A prospective evaluation.

J Infect Public Health 2020 May 18. Epub 2020 May 18.

Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, 226003, India.

Objective: Disseminated tuberculosis is characterized with involvement of two or more non-contiguous sites. In this work we evaluated patients of tuberculous meningitis for possible extra-central nervous system tuberculosis.

Method: This prospective observational study was performed at a tertiary care institute in Northern India. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jiph.2020.04.011DOI Listing

Iatrogenic biological fracture of the cervical spine during gradual halo traction for kyphotic deformity correction: case report.

BMC Musculoskelet Disord 2020 May 21;21(1):318. Epub 2020 May 21.

Department of Orthopaedics and Traumatology, The University of Hong Kong, Professorial Block, 5th Floor, 102 Pokfulam Road, Pokfulam, Hong Kong SAR, China.

Background: Severe kyphotic deformities carry high risk for neurological injuries as osteotomies are often required for correction. Surgeons often utilize a staged approach for dealing with these conditions starting with a period of halo traction to stretch tight soft tissues and partially correct the deformity, followed by surgery. Halo traction is a relatively safe procedure and complications are uncommon. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12891-020-03350-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243305PMC

The first rare and fatal case of invasive aspergillosis of spinal cord due to in an Iranian child with chronic granulomatosis disease: review of literature.

Curr Med Mycol 2020 ;6(1):55-60

Department of Infectious Diseases, Children Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

Background And Purpose: Invasive aspergillosis (IA) of the central nervous system (CNS) is a devastating complication which is rarely reported in immunocompromised children. In this case presentation, we reported a rare and fatal IA with spinal cord involvement in a 10-year-old child with X-linked chronic granulomatosis disease (CGD).

Case Report: The child had a previous history of pulmonary tuberculosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18502/cmm.6.1.2551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217256PMC
January 2020

Examining variation in skeletal tuberculosis in a late pre-contact population from the eastern mountains of Peru.

Int J Paleopathol 2020 May 13;30:22-34. Epub 2020 May 13.

School of Human Evolution and Social Change, Arizona State University, Phoenix metropolitan area, AZ, United States.

Objective And Materials: This research evaluates the presence and chronology of tuberculosis (TB) in the northeastern highlands of Peru (CE 800-1535) through the analysis of osseous lesions from Pre-Contact Kuelap, Chachapoyas.

Methods: We examined macroscopic lesion morphology and distribution from the skeletal series (MNI = 207).

Results: We determined that skeletal evidence was highly consistent with advanced multifocal and spinal tuberculosis in 13 individuals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpp.2020.04.002DOI Listing

Multidrug-resistant tuberculosis of lumbosacral spine producing extensive destruction with lumbosacral kyphosis.

BMJ Case Rep 2020 May 14;13(5). Epub 2020 May 14.

Department of Orthopedics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.

It is uncommon to get lumbosacral junction deformity due to tuberculosis. Lumbosacral junction alignment is of paramount importance in maintaining global sagittal balance. In this case report, we present a case of a 42-year-old woman with multidrug-resistant tuberculosis of lumbosacral spine with complete destruction of L3, L4 and L5 vertebra with partial destruction of L2 and S1 vertebra leading to significant shortening and lumbosacral kyphosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2020-234246DOI Listing

Immune checkpoint inhibitor use and tuberculosis: a systematic review of the literature.

Eur J Cancer 2020 Jun 3;132:168-175. Epub 2020 May 3.

Department of Medicine, MedStar Georgetown University Hospital, Washington, DC, USA; Lombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, Washington, DC, USA. Electronic address:

Background: An amassing body of evidence exists to support an association between the use of immune checkpoint inhibitors (ICIs) and the development of tuberculosis (TB).

Methods: We performed a systematic review of the literature to assess the nature of this relationship using PubMed, EMBASE and meeting proceedings.

Results: We have identified 16 patients who developed active TB during immunotherapy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2020.03.015DOI Listing

Distribution of Linezolid in Tuberculosis Lesions in Patients with Spinal Multidrug-Resistant Tuberculosis.

Antimicrob Agents Chemother 2020 Jun 23;64(7). Epub 2020 Jun 23.

Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China

Linezolid has strong antimicrobial activity against the multidrug-resistant (MDR) strains of Little is known about the distribution of linezolid in tuberculosis (TB) lesions in patients with MDR-TB. The aim of this study was to evaluate the distribution of linezolid in TB lesions in patients with spinal MDR-TB. Nine patients with spinal MDR-TB were enrolled prospectively from August 2019 to February 2020. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.00450-20DOI Listing
June 2020
4.476 Impact Factor

The prevalence, diagnosis and surgical risk factors of spinal tuberculosis in children.

Trop Med Int Health 2020 Jul 11;25(7):834-838. Epub 2020 Jun 11.

Department of Thoracic Surgery, Shandong Provincial Chest Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Objective: To date, the burden of childhood spinal TB in China has not been estimated, and current treatment is hindered by a lack of evidence. This study aimed to review our experience of childhood spinal TB.

Methods: We reviewed the medical records of paediatric patients (≤15 years) admitted for spinal TB (confirmed or possible) at Shandong Provincial Chest Hospital from January 2006 to December 2019. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/tmi.13411DOI Listing

Edward Harrison (1759-1838): An overlooked advocate of EcoHealth and One Health in the early 19th century.

Authors:
Neil J Morley

J Med Biogr 2020 Apr 28:967772020921668. Epub 2020 Apr 28.

School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey, UK.

Edward Harrison (1759-1838) was an English doctor best known for his ground-breaking treatments of spinal deformities and his failed attempts at medical reforms in the early 19th century. However, with the encouragement of his patient and patron Sir Joseph Banks, he also undertook comparative research on the influence of environmental factors on infectious diseases of medical and veterinary importance using approaches that were forerunners of the modern-day concepts of EcoHealth and One Health. His works in this field, particularly his study of sheep rot, are highlighted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0967772020921668DOI Listing

Unilateral or Bilateral Percutaneous Endoscopic Debridement and Lavage Treatment for Lumbar Spinal Tuberculosis.

World Neurosurg 2020 Apr 25. Epub 2020 Apr 25.

Department of Orthopedics, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.

Objective: To compare the clinical outcome between bilateral percutaneous endoscopic debridement and lavage (PEDL) and unilateral PEDL treatment for lumbar spine tuberculosis (LST).

Methods: A total of 40 patients with LST who underwent either bilateral PEDL (group A) or unilateral PEDL (group B) were reviewed. Perioperative parameters were assessed by operative time, intraoperative fluoroscopy times, and days of postoperative continuous irrigation and vacuum drainage. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2020.04.132DOI Listing

Spinal-Pelvic Dissociation in Pregnancy: Surgical Fixation of Culture-Negative Extrapulmonary Tuberculosis.

Case Rep Orthop 2020 10;2020:9769076. Epub 2020 Apr 10.

St. George's Hospital, University of London, UK.

A 33-year-old gravid female from Pakistan presented to the Emergency Department with persistent, intractable low back pain and neuropathic left L5 leg pain, associated with a left foot drop. There was a notable history of weight loss for 1 year. Investigations revealed a large collection in the right posterior paraspinal muscles tracking from a large bony defect in the right half of her sacrum extending into the pelvis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2020/9769076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171626PMC

Treatment of Spinal Tuberculosis of GATA Type III: Primary Posterior Debridement Combined with Osteotomy Parallel to the Endplates for Reconstruction.

Orthop Surg 2020 Jun 23;12(3):997-1004. Epub 2020 Apr 23.

Department of Orthopaedics, The Second Hospital of Shanxi Medical University, Taiyuan, China.

To evaluate the curative effect of one-stage posterior debridement and osteotomy parallel to the endplates for reconstruction, deformity correction, and tuberculosis control on treating the spinal tuberculosis of graded GATA III. From July of 2012 to December of 2017, there were 36 cases from the Second Hospital of Shanxi Medical University with thoracic and lumbar tuberculosis graded GATA III, in which we used osteotomy parallel to the endplates and reconstruction for treatment,16 for males and 20 for females. The local Cobb angles of kyphosis of all patients are greater than or equal to 20. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/os.12650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307253PMC

[Diagnosis and treatment of primary intraspinal abscess].

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Apr;52(2):275-280

Department of Neurosurgery, Peking University Third Hospital, Beijing, 100191, China.

Objective: To summarize the feature and treatment of the primary intraspinal abscess in order to improve the prognosis.

Methods: In the study, 13 cases of primary intraspinal abscess of the recent 20 years were retrospectively analyzed. The history, etiology, pathogen, surgical methods and prognosis were summarized. Read More

View Article

Download full-text PDF

Source

Multiple Intracranial Tuberculomas with an Intra-medullary Spinal Cord Tuberculoma in a Pediatric Patient.

Cureus 2020 Mar 12;12(3):e7248. Epub 2020 Mar 12.

Internal Medicine, The University of Texas Health Science Center/Christus Good Shepherd Medical Center, Longview, USA.

Central nervous system (CNS) tuberculosis (TB), caused by Mycobacterium tuberculosis (MT), is a severe form of TB, which presents as meningitis, cerebritis, abscesses, spinal tuberculous arachnoiditis, and rarely tuberculomas. CNS TB is prevalent in the underdeveloped or developing world and is common in malnourished, alcoholics, children, young adults, immunocompromised, and cancer patients. Intracranial tuberculomas (ICT) can present with symptoms and signs of focal neurological deficits with or without systemic manifestations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.7248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152571PMC

Effectiveness of dolutegravir-based antiretroviral treatment for HIV-2 infection: retrospective observational study from Western India.

J Antimicrob Chemother 2020 Jul;75(7):1950-1954

Institute of Infectious Diseases, Pune, India.

Background: Data on the use of dolutegravir for treatment of HIV-2 infection are limited.

Objectives: To assess the effectiveness of dolutegravir in people living with HIV-2 (PLHIV-2).

Methods: A retrospective chart review was performed in two clinics in Western India. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jac/dkaa112DOI Listing

An unusual case of extensive contiguous cervicothoracic spinal tuberculosis involving fourteen damaged segments: A case report.

Int J Surg Case Rep 2020 6;69:109-113. Epub 2020 Feb 6.

Department of Orthopaedics & Traumatology, Faculty of Medicine Universitas Indonesia, Jalan Salemba No. 4, Jakarta Pusat, 10430, Indonesia.

Introduction: Cervicothoracic spinal tuberculosis (CTSTB) is a rare and disabling disease involving the mobile, transitional zone between the lordotic cervical and the kyphotic thoracic spine. Approximately half of those cases involves one or two segments of cervicothoracic vertebrae. We reported a 28-year-old female with tuberculous involvement of fourteen contiguous vertebral segments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijscr.2020.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210701PMC
February 2020

rs6127698 polymorphism in the MC3R gene and susceptibility to multifocal tuberculosis in southern Chinese Han population.

Infect Genet Evol 2020 Aug 31;82:104292. Epub 2020 Mar 31.

Department of Spine Surgery, Xiangya Spinal Surgery Center, Xiangya Hospital, Central South University, Changsha 410008, People's Republic of China.

Objective: To investigate the relationship between melanocortin-3 receptor (MC3R) gene polymorphism and tuberculosis (TB) susceptibility in Han population in southern China.

Methods: A total of 341 patients with TB (173 with pulmonary TB and 168 with multifocal TB) and 359 healthy controls were enrolled. Genotyping was performed by PCR and DNA sequencing, and detection of protein was performed by western blot. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.meegid.2020.104292DOI Listing

MRI findings in Pott's spine and correlating clinical progress with radiological findings.

Neuroradiology 2020 Jul 23;62(7):825-832. Epub 2020 Mar 23.

Department of Radiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow, Uttar Pradesh, 226014, India.

Purpose: To document magnetic resonance imaging (MRI) changes in Pott's spine and to correlate these with clinical findings and outcome.

Methods: Patients with Pott's spine having more than one set of MRI were included in the study. Patients were grouped according to timing of their second MRI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00234-020-02402-2DOI Listing
July 2020
2.485 Impact Factor

Short-term outcome of lamina-sparing decompression in thoracolumbar spinal tuberculosis.

J Neurosurg Spine 2020 Mar 20:1-8. Epub 2020 Mar 20.

Objective: The authors sought to assess the outcomes of lamina-sparing decompression using a posterior-only approach in patients with thoracolumbar spinal tuberculosis (TB). In patients with spinal TB with paraplegia, anterior decompression yields excellent results because it allows direct access to the diseased part of the vertebra, but the anterior approach has related morbidities. Posterior and posterolateral decompression mitigate approach-related morbidities; however, these approaches destabilize the already diseased segment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3171/2020.1.SPINE191152DOI Listing

An improved protocol to establish experimental tuberculous meningitis in the rabbit.

MethodsX 2020 21;7:100832. Epub 2020 Feb 21.

Public Health Research Institute of New Jersey Medical School, United States.

Tuberculous meningitis (TBM), caused by (Mtb), is the deadliest form of tuberculosis in humans, particularly in children and the geriatric population. However, the host-pathogen interactions underlying TBM is not well understood. Rabbits are a valuable model system to study TB in humans. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mex.2020.100832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078415PMC
February 2020

Profile of osteoarticular tuberculosis in children.

Indian J Tuberc 2020 Jan 22;67(1):43-45. Epub 2019 Aug 22.

Department of Pediatric Orthopedics, B.J. Wadia Hospital for Children, Mumbai, India.

Objective: To determine clinical profile of osteoarticular tuberculosis (TB) in children.

Methods: Cross-sectional analysis from 2007 to 2013. All patients diagnosed with bone TB, spinal TB or TB abscesses were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijtb.2019.08.014DOI Listing
January 2020

Tuberculous meningitis manifesting with neuroregression in a eleven month child.

Indian J Tuberc 2020 Jan 8;67(1):136-138. Epub 2020 Jan 8.

Department of Pediatrics, Mahatma Gandhi Medical College & Research Institute, Sri Balaji Vidyapeeth University, Pillayarkuppam, Puducherry, 607402, India.

Tuberculosis (TB) is a disease of diverse manifestations. In children, neurotuberculosis is the severest form, which when left untreated can have deleterious consequences. There has been reports on pediatric TB meningitis manifesting with fever and seizures, altered sensorium or focal deficits. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijtb.2020.01.001DOI Listing
January 2020

Tuberculous spondylodiscitis in abscess form.

Rev Soc Bras Med Trop 2020;53:e20190581. Epub 2020 Mar 16.

Department of Radiology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0037-8682-0581-2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094044PMC

Surgical strategy for correction of severe, rigid, post-tubercular cervical kyphosis: an experience of two cases.

Spine Deform 2020 Mar 17. Epub 2020 Mar 17.

Department of Orthopaedics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Study Design: Case series.

Objectives: To describe a novel surgical strategy for severe, rigid post-tubercular cervical kyphosis with treatment outcomes in two patients.

Background Data: Spinal tuberculosis is a common cause of kyphotic deformity in the developing world with 3-5% of non-operatively managed patients ending up with kyphosis exceeding 60°. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s43390-020-00104-6DOI Listing

Extend of Skipped Multifocal Noncontiguous Spinal Tuberculosis Beyond Imagination: A Rare Case Report and Literature Review.

Asian J Neurosurg 2020 Jan-Mar;15(1):136-139. Epub 2020 Feb 25.

Department of Orthopaedic and Spine, Grant Medical College, Sir J. J. Group of Hospitals, Mumbai, Maharashtra, India.

Skipped multifocal extensive spinal tuberculosis involving the whole spine is very rare, which presents with atypical presentations and imaging features. So far, only five cases have been reported. Most of these patients have only two noncontiguous lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ajns.AJNS_345_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057892PMC
February 2020

[Intramedullary Pott's abscess: a case study].

Pan Afr Med J 2019 6;34:186. Epub 2019 Dec 6.

Service de Neurochirurgie, Hôpital National de Niamey, Niamey, République du Niger.

Central Nervous System (CNS) Tuberculosis (TB) is rare. It manifests in many forms, but the association between intramedullary abscess and multifocal Pott's disease is exceptional. We report the case of a 23-year old female patient diagnosed with multifocal Pott's disease at L2-L3 and L4-L5 based on computed tomography (CT) scan of the spine. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11604/pamj.2019.34.186.20838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060905PMC
December 2019

Letter to Editor concerning "Diagnostic accuracy of whole spine magnetic resonance imaging in spinal tuberculosis validated through tissue studies" by Kanna RM, et al. (Eur Spine J; 28 [2019]:3003-3010).

Eur Spine J 2020 May 16;29(5):1186-1187. Epub 2020 Mar 16.

Department of Spine Services, Indian Spinal Injuries Centre, Vasant kunj, Sector C, New Delhi, 110070, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00586-020-06371-1DOI Listing