554 results match your criteria Postterm Pregnancy
Rom J Anaesth Intensive Care 2018 Oct;25(2):111-116
Tampa General Hospital, University of South Florida Morsani College of Medicine, USA.
Background And Aims: Atrial fibrillation (AF) is the most common arrhythmia seen clinically. Due to the lack of literature and guidelines on maternal AF as a postoperative complication following cesarean delivery (CD), we undertook a study to characterize parturients who developed AF following CD and to evaluate arrhythmia management and outcomes in this patient population.
Methods: After receiving ethics committee approval, a retrospective chart review was performed to determine the incidence, possible risk factors, treatment, and outcome of women who developed AF following CD performed between 2003 and 2012 at New York Methodist Hospital in Brooklyn, New York. Read More
Int J Gynecol Cancer 2018 Nov;28(9):1766-1771
Pôle Information Médicale Evaluation Recherche, Equipe d'Accueil 4129, Hospices Civils de Lyon, Lyon.
Objective: This study aimed to assess the outcome of first-line hysterectomy in patients diagnosed as having gestational trophoblastic neoplasia (GTN) whose postoperative imaging showed lung images considered as metastases.
Methods: From 1999 to 2016, patients no longer wishing to conceive, treated by their initial physician by hysterectomy, and whose postoperative imaging workup showed lung images considered as metastasis were identified in the French Trophoblastic Disease Reference Center database. We sought to identify significant predictive factors of requiring salvage chemotherapy. Read More
BMC Pregnancy Childbirth 2018 Sep 20;18(1):380. Epub 2018 Sep 20.
Department of Obstetrics and Gynaecology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6523, GA, Nijmegen, the Netherlands.
Background: Late- and postterm pregnancy are associated with adverse perinatal outcomes, like perinatal death. We evaluated causes of death and substandard care factors (SSFs) in term and postterm perinatal death.
Methods: We used data from the Perinatal Audit Registry of the Netherlands (PARS). Read More
Midwifery 2018 Nov 11;66:111-118. Epub 2018 Aug 11.
Department of Obstetrics and Gynaecology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
Background: Postterm pregnancy is associated with increased perinatal risk. The WHO defines postterm pregnancy as a pregnancy at or beyond 42 weeks + 0 days, though currently labour is induced at 41 weeks in many settings. Guidelines on timing of labour induction are frequently based on the Cochrane systematic review 'Induction of labour for improving birth outcomes for women at or beyond term' in which is concluded that a policy of induction of labour is associated with fewer adverse perinatal outcome and fewer Caesarean sections. Read More
JMIR Res Protoc 2018 Aug 23;7(8):e10095. Epub 2018 Aug 23.
Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland.
Background: Preterm birth (PTB) is a leading cause of infant morbidity and mortality worldwide. Every year, 20 million babies are born with low birthweight (LBW), about 96% of which occur in low-income countries. Despite the associated dangers, in about 40%-50% of PTB and LBW cases, the causes remain unexplained. Read More
JAMA Pediatr 2018 Oct;172(10):949-957
Department of Obstetrics and Gynecology, Winthrop Hospital, New York University, Mineola.
Importance: Preterm and postterm deliveries have declined since 2005 in the United States, but the association between these changes and neonatal mortality remains unknown.
Objective: To estimate changes in the gestational age distribution among spontaneous and clinician-initiated deliveries between 2006 and 2013 and associated changes in neonatal mortality.
Design, Setting, And Participants: A retrospective cohort analysis was conducted of 22 million singleton live births without major malformations in the United States from 2006 to 2013. Read More
Neonatal Netw 2018 May;37(3):141-148
The approach to the management of meconium-stained newborns in the delivery room has been changing for over 40 years. The goal is to prevent meconium aspiration syndrome (MAS) and complications related to MAS. For decades, airway obstruction was believed to be a major component of MAS and, consequently, suction maneuvers to remove meconium from the airways were recommended to decrease the frequency and severity of MAS. Read More
Eur J Paediatr Neurol 2018 Jul 20;22(4):682-689. Epub 2018 Apr 20.
Department of Neonatology, Division of Paediatrics, University Medical Centre Ljubljana, Bohoriceva 20, 1000, Ljubljana, Slovenia. Electronic address:
Background: The quality of general movements (GMs) has proven to have predictive value for the developmental outcome, but this has not yet been studied in twins.
Aims: Our aim was to analyse the quality of GMs and neurological and developmental outcome in relation to the gestational age (GA), mode of conception and other perinatal risk factors in a group of twins.
Study Design: The documentation of twins referred for follow-up in the period from 1998 to 2016 was studied retrospectively. Read More
Int J Fertil Steril 2018 Jul 18;12(2):106-113. Epub 2018 Mar 18.
Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
Background: Abnormalities in birth weight and gestational age cause several adverse maternal and infant outcomes. Our study aims to determine the potential factors that affect birth weight and gestational age, and their association.
Materials And Methods: We conducted this cross-sectional study of 4415 pregnant women in Tehran, Iran, from July 6-21, 2015. Read More
Exp Brain Res 2018 04 15;236(4):1139-1148. Epub 2018 Feb 15.
Department of Physical and Health Education, Graduate School of Education, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan.
We examined the characteristics of spontaneous movements at 9-20 weeks postterm age in very low birth-weight infants who later developed autism spectrum disorder (ASD). We analyzed video recordings of spontaneous movements of 39 children who had no clinical issues [typically developing (TD) group], 21 children who showed developmental delay, and 14 children who were diagnosed with ASD (ASD group) at 6 years of age. Head position in each video frame was classified by visual inspection. Read More
Radiol Med 2018 Jun 1;123(6):434-440. Epub 2018 Feb 1.
Faculty of Medicine, Department of Radiology, Erciyes University, Kayseri, Turkey.
Objective: To assess symmetrical increased echogenicity of bilateral caudothalamic grooves (SIEBCG) detected on newborn cranial ultrasonography (CUS) using magnetic resonance susceptibility-weighted imaging (SWI).
Materials And Methods: A total of 14 newborns (8 girls; 12 premature with mean gestational age of 30 weeks and 5 days, 2 mature) who were detected to have SIEBCG on routine serial CUS and underwent cranial magnetic resonance imaging (MRI) were recruited for the study. The cranial MRI examinations including SWI acquired on the same day of SIEBCG detection and serial CUS to assess the progress of SIEBCG lesions in the following 6 month period were retrospectively evaluated and compared for the presence of germinal matrix hemorrhage. Read More
Obstet Gynecol 2018 02;131(2):281-289
Center for Perinatal Research, the Research Institute at Nationwide Children's Hospital, the Departments of Obstetrics and Gynecology and Pediatrics and the College of Public Health, The Ohio State University, and Research Information Solutions and Innovation (RISI), the Research Institute at Nationwide Children's Hospital, Columbus, and Cincinnati Children's Hospital Medical Center, Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati, Ohio.
Objective: To compare preterm birth rates and gestational length in four race-nativity groups including Somali Americans.
Methods: Using a retrospective cohort study design of Ohio birth certificates, we analyzed all singleton births between 2000 and 2015 from four groups of women categorized as U.S. Read More
J Matern Fetal Neonatal Med 2018 Jan 4:1-6. Epub 2018 Jan 4.
c Department of Obstetrics and Gynecology , Soroka University Medical Center, Ben-Gurion University of the Negev , Beer-Sheva , Israel.
Objective: To investigate whether postterm pregnancy (≥42 0/7 weeks' gestation) increases the risk for adverse perinatal outcome.
Study Design: In this population based cohort study, all singleton deliveries occurring between 1991 and 2014 in a tertiary medical center were included. Pregnancy and perinatal outcomes were compared between postterm and term deliveries (37 0/7 to 41 6/7 weeks' gestation). Read More
Hematology 2018 Jun 3;23(5):253-262. Epub 2017 Nov 3.
a Department of Occupational and Environmental Health, School of Health Sciences , Wuhan University , Wuhan , People's Republic of China.
Objective: An increasing amount of evidence shows that childhood leukemia is initiated in utero. Birth characteristics initiated in utero, such as gestational age, may play a role in leukemogenesis. The purpose of our meta-analysis is to explore the association between gestational age and childhood leukemia. Read More
J Obstet Gynaecol 2018 Apr 23;38(3):352-358. Epub 2017 Oct 23.
a Department of Molecular and Developmental Medicine , University of Siena , Siena , Italy.
Induction of labour (IOL) is a widely-used practice in obstetrics. Our aim was to evaluate predictors of vaginal delivery in postdate pregnancies induced with prostaglandins. We conducted a retrospective cross-sectional study with analytic component. Read More
J Craniomaxillofac Surg 2017 Nov 19;45(11):1809-1814. Epub 2017 Aug 19.
University of Gothenburg, The Sahlgrenska Academy, Institute of Clinical Sciences, Department of Plastic Surgery, Sahlgrenska University Hospital, Gröna Straket 8, 413 45, Goteborg, Sweden.
Purpose: Craniosynostosis may lead to hampered fetal head molding and birth complications. To study the interaction between single suture craniosynostosis and delivery complications, an international, multicentre, retrospective cohort study was performed.
Materials And Methods: All infants born between 2006 and 2012 in the Netherlands and Sweden with sagittal or metopic suture synostosis were included. Read More
PLoS One 2017 14;12(9):e0184748. Epub 2017 Sep 14.
Division of Pediatrics, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Background: Birth by cesarean section is associated with increased risks of immune disorders. We tested whether establishment of immune function at birth relates to mode of delivery, taking other maternal and infant characteristics into account.
Methods And Findings: Using a prospectively collected database, we retrieved information on maternal and infant characteristics of 6,014 singleton infants delivered from February to April 2014 in Stockholm, Sweden, with gestational age ≥35 weeks, Apgar scores ≥7, and without congenital malformations or any neonatal morbidity. Read More
Paediatr Perinat Epidemiol 2017 11 12;31(6):586-594. Epub 2017 Sep 12.
Centre for Women's Mental Health, Manchester Academic Health Sciences Centre, Institute of Brain Behaviour and Mental Health, University of Manchester, Manchester, UK.
Background: Preterm birth has been linked to increased risk of autism spectrum disorders (ASD), but how this risk changes with gestational age at birth has not been well characterised, especially with regard to co-occurring intellectual disability (ID).
Methods: Register-based cohort study of singleton births in 1984-2007 in Stockholm County, Sweden (N total: 480 728; n ASD: 10 025). We assessed overall and sex-specific, gestational week-specific prevalence estimates and risk ratios of ASD with and without ID. Read More
PLoS One 2017 4;12(8):e0181794. Epub 2017 Aug 4.
Dept. of Clinical Science, University of Bergen, Bergen, Norway.
Studies using mothers' self-reported information on birth and pregnancy characteristics are common, but the validity of such data is uncertain. We evaluated questionnaire data from the RHINE III study on reproductive health provided by 715 mothers from Bergen, Norway, about their 1629 births between 1967 and 2010, using the Medical Birth Registry of Norway (MBRN) as gold standard. Validity of dichotomous variables (gender, preterm birth [<37 weeks' gestation], postterm birth [>42 weeks' gestation], induction of labour, forceps delivery, vacuum delivery, caesarean section, were assessed by sensitivity, specificity, positive and negative predictive values (PPV and NPV) and Cohen's kappa. Read More
Am J Obstet Gynecol 2017 10 12;217(4):443.e1-443.e11. Epub 2017 Jun 12.
Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Background: Many stillbirths of normally formed fetuses in the third trimester could be prevented via delivery if reliable means to anticipate this outcome existed. However, because the etiology of these stillbirths is often unexplained and although the underlying mechanism is presumed to be hypoxia from placental insufficiency, the placentas often appear normal on histopathological examination. Gestational age is a risk factor for antepartum stillbirth, with a rapid rise in stillbirth rates after 40 weeks' gestation. Read More
Birth 2017 09 22;44(3):209-221. Epub 2017 Mar 22.
School of Medicine, University of New Mexico, Albuquerque, NM, USA.
Background: There is little agreement on who is a good candidate for community (home or birth center) birth in the United States.
Methods: Data on n=47 394 midwife-attended, planned community births come from the Midwives Alliance of North America Statistics Project. Logistic regression quantified the independent contribution of 10 risk factors to maternal and neonatal outcomes. Read More
Clin Lab 2017 Feb;63(2):235-240
Background: To evaluate amniotic fluid pro- and anti-inflammatory cytokine levels in women with postterm and term pregnancies in labor and not in labor.
Methods: The study involved three groups: postterm (Group 1, n = 29), term in labor (Group 2, n = 28), and control (Group 3, n = 30). All groups were compared with respect to age, gravidity, parity, obstetric history, gestation week, cervical dilatation and effacement, maternal serum C-reactive protein and white cell count, amniotic interleukin 4, 6, and 10 levels, birthweight, and cord blood pH. Read More
Am J Obstet Gynecol 2017 Apr 14;216(4):405.e1-405.e6. Epub 2016 Dec 14.
Department of Obstetrics and Gynecology, King Abdulaziz University, Jeddah, Saudi Arabia.
Background: Misoprostol is an effective agent for the induction of labor. Existing guidelines recommend oral misoprostol solution 25 μg every 2 hours. However, more research is required to optimize the use of oral misoprostol solution for the induction of labor. Read More
Acta Obstet Gynecol Scand 2017 Feb 7;96(2):223-232. Epub 2017 Jan 7.
Department of Clinical Cancer Epidemiology, Karolinska Institute, Stockholm, Sweden.
Introduction: In Stockholm County, new guidelines for predicting the day of delivery were introduced in 2010. Recent clinical use has indicated that the predictive quality might be suboptimal. This study compares the accuracy of three equations applied during the first (crown-rump length or bi-parietal diameter) and second trimesters (bi-parietal diameter or bi-parietal diameter combined with femur length). Read More
Obstet Gynecol 2016 12;128(6):1389-1396
Departments of Obstetrics and Gynecology and Public Health & Preventive Medicine, Oregon Health & Science University, Providence Health & Services, Legacy Health, Kaiser Permanente, Northwest Region, and the March of Dimes, Portland, Oregon; and the Center for Health Systems Research, National Institute of Public Health, Cuernavaca, Mexico.
Objective: To evaluate the association of Oregon's hard-stop policy limiting early elective deliveries (before 39 weeks of gestation) and the rate of elective early-term inductions and cesarean deliveries and associated maternal-neonatal outcomes.
Methods: This was a population-based retrospective cohort study of Oregon births between 2008 and 2013 using vital statistics data and multivariable logistic regression models. Our exposure was the Oregon hard-stop policy, defined as the time periods prepolicy (2008-2010) and postpolicy (2012-2013). Read More
AJNR Am J Neuroradiol 2017 01 27;38(1):162-169. Epub 2016 Oct 27.
Department of Pediatrics (A.D.), NorthShore University Health System, Evanston, Illinois.
Background And Purpose: Very preterm infants (birth weight, <1500 g) are at increased risk of cognitive and motor impairment, including cerebral palsy. These adverse neurodevelopmental outcomes are associated with white matter abnormalities on MR imaging at term-equivalent age. Cerebral palsy has been predicted by analysis of spontaneous movements in the infant termed "General Movement Assessment. Read More
Obstet Gynecol 2016 11;128(5):1033-1038
Departments of Obstetrics and Gynecology, University of Colorado, School of Medicine, Aurora, and Denver Health Medical Center and the Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Denver, Denver, Colorado.
Objective: To investigate the relationship between body mass index (BMI) and the onset of parturition throughout gestation.
Methods: This was a secondary analysis of the Maternal-Fetal Medicine Units Network Preterm Prediction Study. Time-to-spontaneous-birth-event (ie, "survival") methods were used to study the association of BMI with the timing of spontaneous onset of labor throughout gestation with indicated births censored at delivery. Read More
J Obstet Gynaecol India 2016 Oct 13;66(Suppl 1):192-7. Epub 2016 Jan 13.
Department of Obstetrics and Gynaecology, Government Medical College, Aurangabad, India.
Aim And Objectives: To review the effects of obesity (BMI > 30) on antepartum risk/intrapartum risk. To study neonatal outcome of pregnant women with raised BMI.
Material Method: BMI of 500 pregnant women booked before 12 weeks calculated and categorised as normal, overweight, obese and morbidly obese at GMCH, Aurangabad. Read More
Arch Gynecol Obstet 2017 Jan 2;295(1):45-50. Epub 2016 Sep 2.
Department of Obstetrics and Gynecology, Sisli Hamidiye Etfal Training and Research Hospital, Halaskargazi caddesi, Etfal sokak, 34360, Sisli, Istanbul, Turkey.
Purpose: We aimed to compare the clinical characteristics and pregnancy outcomes in women who are Syrian refugees and Turkish women who are non-refugees at a maternity center in Istanbul, Turkey.
Methods: A total of 600 singleton pregnancies who delivered at Sisli Hamidiye Etfal Training and Research Hospital were included in the study. Demographic data, obstetrical history, clinical findings, obstetrical and neonatal outcomes were compared between 300 Syrian refugees and 300 control patients. Read More
Geburtshilfe Frauenheilkd 2016 Jul;76(7):793-798
University Hospital of Cologne, Department of Obstetrics and Gynecology, Cologne, Germany.
Introduction: This study aimed to determine the effects of induction of labour in late-term pregnancies on the mode of delivery, maternal and neonatal outcome.
Methods: We retrospectively analyzed deliveries between 2000 and 2014 at the University Hospital of Cologne. Women with a pregnancy aged between 41 + 0 to 42 + 6 weeks were included. Read More
Ceska Gynekol 2016 04;81(2):98-103
Unlabelled: This review presents the up-to-date information from published resources on the issue of Posterm pregnancy (Medline, Cochrane Database, ACOG, RCOG, SOGC) and complements the presented guidelines. The most of resources are using the term "postterm pregnancy" for pregnancy reaching or exceeding 42+0 weeks and days of gestation, while late pregnancy is defined as a period in between 41+0 and 41+6.The exact determination of gestational age is necessary for exact diagnosis and appropriate management of late and postterm pregnancy, because these pregnancies have increased risk of perinatal morbidity and mortality. Read More
Early Hum Dev 2016 09 5;100:27-32. Epub 2016 Jul 5.
Department of Rehabilitation, Children's Hospital of Fudan University, Key Laboratory of Neonatal Diseases, Ministry of Health, Shanghai, PR China. Electronic address:
Background: Studies on motor performance and its early markers are rare in China, especially in very low birth weight (VLBW) infants.
Objective: Apart from the assessment of the inter-scorer agreement, we aimed to analyze to what extent the motor repertoire at 10 to 18weeks postterm was related to neonatal complications, and gross and fine motor performance at 12months after term.
Study Design: Exploratory prospective study. Read More
BMC Cancer 2016 06 2;16:347. Epub 2016 Jun 2.
Departments of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, 100730, Beijing, People's Republic of China.
Background: The objective of our study was to investigate the clinical characteristics and prognosis of postterm choriocarcinoma patients at Peking Union Medical College Hospital within the past 30 years.
Methods: The clinical characteristics and pertinent follow-up data of 272 patients with postterm choriocarcinoma diagnosed from December 1985 through December 2014 in our hospital were reviewed. The clinical characteristics of two cohorts cut off at 2006 were compared using χ (2) tests. Read More
Pediatrics 2016 06;137(6)
Department of Obstetrics and Gynecology, and.
Background And Objectives: Neonatal outcomes vary by gestational age. We evaluated the association of early-term, full-term, and postterm birth with asphyxia, neurologic morbidity, and perinatal mortality.
Methods: Our register-based study used retrospective data on 214 465 early-term (37(+0)-38(+6) gestational weeks), 859 827 full-term (39(+0)-41(+6)), and 55 189 postterm (≥42(+0)) live-born singletons during 1989-2008 in Finland. Read More
Breastfeed Med 2016 Apr 23;11:119-25. Epub 2016 Mar 23.
2 Department of Obstetrics and Gynecology, Penn State College of Medicine , Hershey, Pennsylvania.
Objectives: The primary objective was to determine the rate of breastfeeding by gestational age reported by new mothers 1 month postpartum, with particular focus on early term newborns (37-38(6)/7 weeks).
Materials And Methods: Three thousand six primiparous women aged 18-36 years were interviewed during their third trimester and again 1 month postpartum. Logistic regression analysis was used to model the association between gestational age and breastfeeding 1 month postpartum among those who reported that they planned to breastfeed, controlling for potentially confounding variables. Read More
J Matern Fetal Neonatal Med 2017 Jan 14;30(2):219-223. Epub 2016 Apr 14.
a Department of Obstetrics and Gynecology and.
Objective: To compare maternal and neonatal outcomes associated with a policy for induction of labor at ≥ 41 versus at ≥42 weeks'.
Study Design: Retrospective cohort study of a 2 years' period before and after policy change from induction of labor at ≥ 42 gestational weeks' versus ≥41 gestational weeks.
Results: During the 41-policy period (N = 968), the induction rate was higher, 60% versus 40% (p < 0. Read More
BMC Pregnancy Childbirth 2016 Mar 7;16:49. Epub 2016 Mar 7.
Gothenburg University, Perinatal centre, Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, Sahlgrenska University Hospital, East, S-416 85, Gothenburg, Sweden.
Background: Observational data shows that postterm pregnancy (≥42 gestational weeks, GW) and late term pregnancy (≥41 GW), as compared to term pregnancy, is associated with an increased risk for adverse outcome for the mother and infant. Standard care in many countries is induction of labour at 42 GW. There is insufficient scientific support that induction of labour at 41 GW, as compared with expectant management and induction at 42 GW will reduce perinatal mortality and morbidity without an increase in operative deliveries, negative delivery experiences or higher costs. Read More
J Clin Sleep Med 2016 Mar;12(3):429-45
Unlabelled: In March 2014, the American Academy of Sleep Medicine (AASM) Board of Directors requested the Scoring Manual Editorial Board develop rules, terminology, and technical specifications for scoring sleep/wake states in full-term infants from birth to 2 mo of age, cognizant of the 1971 Anders, Emde, and Parmelee Manual for Scoring Sleep in Newborns. On July 1, 2015, the AASM published rules for scoring sleep in infants, ages 0-2 mo. This evidence-based review summarizes the background information provided to the Scoring Manual Editorial Board to write these rules. Read More
J Prenat Med 2015 Jan-Jun;9(1-2):12-5
Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy.
Objective: to compare perinatal outcome in induced postterm pregnancies with normal amniotic volume and in patients with prolonged pregnancy undergone induction for oligohydramnios, evaluated by two different ultrasonographic methods.
Methods: amniotic fluid volume was measured, using Single Deepest Vertical Pocket (SDVP) and Amniotic Fluid Index (AFI), in 961 singleton uncomplicated prolonged pregnancies. In 109 of these patients, hospitalization was planned for induction of labor, during or after 42 weeks of gestation, for oligohydramnios, postterm pregnancy and other indications in 47, 51 and 11 cases, respectively. Read More
J Dev Behav Pediatr 2016 Feb-Mar;37(2):177-8
Department of Health Sciences, University of Leicester, Leicester, United Kingdom.
J Dev Behav Pediatr 2016 Feb-Mar;37(2):177
University of Washington, Seattle, WA.
Am J Obstet Gynecol 2015 Oct;213(4 Suppl):S9.e1, S9-11
Faculty of Medicine, University of Oslo, and Department of Obstetrics and Department of Gynecology, Oslo University Hospital, Oslo, Norway.
The maternal syndrome of preeclampsia is mediated by dysfunctional syncytiotrophoblast (STB). When this is stressed by uteroplacental malperfusion, its signaling to the mother changes, as part of a highly coordinated stress response. The STB signals are both proinflammatory and dysangiogenic such that the preeclamptic mother has a stronger vascular inflammatory response than normal, with an antiangiogenic bias. Read More
Biomed Res Int 2015 27;2015:978079. Epub 2015 Aug 27.
Department of Obstetrics and Gynecology, and Department of Clinical and Experimental Medicine, Linköping University, 581 83 Linköping, Sweden.
Objective: To determine predictive risk factors for Apgar scores < 7 at 5 minutes at two hospitals providing tertiary care and secondary care, respectively.
Methods: A retrospective registry cohort study of 21126 births (2006-2010) using data from digital medical records. Risk factors were analyzed by logistic regression analyses. Read More
Pediatr Infect Dis J 2016 Jan;35(1):61-5
From the *The Child and Adolescent Clinic 4072, Copenhagen University Hospital Rigshospitalet; †Research Unit, Women's and Children's Health, The Juliane Marie Centre for Women, Children and Reproduction, Copenhagen University Hospital Rigshospitalet, Copenhagen; ‡Pediatric Department, University Hospital Naestved, Naestved; §Department of Public Health, University of Copenhagen; and ¶Coraxo Consulting, Copenhagen, Denmark.
Background: The aim of this study is to identify the risk factors for hospitalization for respiratory syncytial virus (RSV) infection in Danish children.
Methods: This is a population-based cohort study with follow-up till 24 months of age. A total of 421,943 Danish children were divided into 5 groups based on gestational age (23-32, 33-35, 36, 37-41 and 42-45 weeks). Read More
BMC Pregnancy Childbirth 2015 Aug 14;15:168. Epub 2015 Aug 14.
Department of Public Health and Caring Sciences, Uppsala University, Uppsala, SE-75122, Sweden.
Background: Women are recommended to perform regular exercise during pregnancy but the impact of physical fitness on duration of gestation and miscarriage is inconsistent. In addition, a dose-response relation between the amount of weekly exercise and increased risk of miscarriage in early pregnancy has been observed. Previous studies have mostly used an epidemiologic method. Read More
Eur J Obstet Gynecol Reprod Biol 2015 Oct 9;193:70-4. Epub 2015 Jun 9.
Academic Medical Center, University of Amsterdam, Department of Obstetrics and Gynaecology, Amsterdam, The Netherlands.
Objective: To assess the recurrence rate of postterm delivery (gestational age at or beyond 42+0 weeks or 294 days) and to describe maternal and perinatal outcomes after previous postterm delivery.
Study Design: From the longitudinal linked Netherlands Perinatal Registry database, we selected all singleton primiparous women who delivered between 37+0 and 42+6 weeks with a subsequent singleton pregnancy from 1999 to 2007. We excluded congenital abnormalities. Read More
BMC Pregnancy Childbirth 2015 Aug 5;15:163. Epub 2015 Aug 5.
University of Oslo, Faculty of Medicine, Institution of Clinical Medicine, P.O. Box 1171, Blindern, 0318, Oslo, Norway.
Background: Immigrants have higher risks for some adverse obstetric outcomes. Furthermore, refugees are reported to be the most vulnerable group. This study compared obstetric outcomes between immigrant women originating from conflict-zone countries and ethnic Norwegians who gave birth in a low-risk setting. Read More
Vaccine 2015 Nov 21;33(48):6884-91. Epub 2015 Jul 21.
University of California San Diego School of Medicine, USA.
Background: We assessed the risk of spontaneous abortion (SA) after inadvertent exposure to HPV-16/18-vaccine during pregnancy using an observational cohort design.
Methods: The study population included women aged 15-25 years registered with the Clinical Practice Research Datalink General Practice OnLine Database in the United Kingdom (UK), who received at least one HPV-16/18-vaccine dose between 1st September 2008 and 30th June 2011. Exposed women had the first day of gestation between 30 days before and 45 days (90 days for the extended exposure period) after any HPV-16/18-vaccine dose. Read More
Endocrinology 2015 Oct 7;156(10):3828-41. Epub 2015 Jul 7.
Robinson Research Institute and School of Medicine (H.H.W., C.D., P.Y.C., M.R.H., L.M.M., S.A.R.), University of Adelaide, Adelaide SA 5005, Australia; Chemical Biology Research Branch (K.C.R.), National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland 20892; and Departments of Obstetrics and Gynecology, Pediatrics and Physiology (D.M.O.), University of Alberta, Edmonton, Canada AB TG62S2.
An inflammatory response is instrumental in the physiological process of parturition but the upstream signals initiating inflammation are undefined. Because endogenous ligands for Toll-like receptor 4 (TLR4) are released in late gestation, we hypothesized that on-time labor requires TLR4 signaling, to trigger a cytokine and leukocyte response and accelerate the parturition cascade. In pregnant TLR4-deficient (Tlr4-/-) mice, average gestation length was extended by 13 hours and increased perinatal mortality was seen compared with wild-type controls. Read More
Minerva Ginecol 2015 Aug;67(4):365-73
Department of Medical Surgical Specialties, Gynecology and Obstetrics Section, University of Catania, Catania, Italy -
Prolonged pregnancy is defined as a pregnancy that extends beyond 42 weeks of gestation (294 days) from the first day of the last normal menstrual period. An accurate estimation of the 'natural' incidence of prolonged pregnancy would require meticulous early pregnancy dating. The use of ultrasound to establish gestational age reduces the number of pregnancies that are classified as prolonged. Read More