389 results match your criteria Postterm Pregnancy


Prevalence of postterm births and associated maternal risk factors in China: data from over 6 million births at health facilities between 2012 and 2016.

Sci Rep 2019 Jan 22;9(1):273. Epub 2019 Jan 22.

National Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.

Postterm births are associated with an increased risk of adverse perinatal outcomes, but few studies have investigated the epidemiological characteristics of postterm births. We aimed to estimate the prevalence of postterm births and examine the potential association between maternal sociodemographic and obstetric characteristics and postterm births. Data were collected from China's National Maternal Near Miss Surveillance System, 2012-2016. Read More

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http://dx.doi.org/10.1038/s41598-018-36290-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342977PMC
January 2019

Women's experiences of postterm induction of labor: A systematic review of qualitative studies.

Birth 2018 Dec 18. Epub 2018 Dec 18.

DEFACTUM -Public Health and Health Services Research, Central Denmark Region, Aarhus, Denmark.

Background: Over the last decade, induction of labor (IOL) in postterm pregnancies has increased. Studies have shown the medical advantages of postterm IOL, but less is known about the perspectives of the pregnant women. This review aimed to summarize the current qualitative evidence on women's experience of postterm IOL. Read More

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http://dx.doi.org/10.1111/birt.12412DOI Listing
December 2018

Perinatal death beyond 41 weeks pregnancy: an evaluation of causes and substandard care factors as identified in perinatal audit in the Netherlands.

BMC Pregnancy Childbirth 2018 Sep 20;18(1):380. Epub 2018 Sep 20.

Department of Obstetrics and Gynaecology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6523, GA, Nijmegen, the Netherlands.

Background: Late- and postterm pregnancy are associated with adverse perinatal outcomes, like perinatal death. We evaluated causes of death and substandard care factors (SSFs) in term and postterm perinatal death.

Methods: We used data from the Perinatal Audit Registry of the Netherlands (PARS). Read More

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http://dx.doi.org/10.1186/s12884-018-1973-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149052PMC
September 2018
12 Reads

Timing induction of labour at 41 or 42 weeks? A closer look at time frames of comparison: A review.

Midwifery 2018 Nov 11;66:111-118. Epub 2018 Aug 11.

Department of Obstetrics and Gynaecology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.

Background: Postterm pregnancy is associated with increased perinatal risk. The WHO defines postterm pregnancy as a pregnancy at or beyond 42 weeks + 0 days, though currently labour is induced at 41 weeks in many settings. Guidelines on timing of labour induction are frequently based on the Cochrane systematic review 'Induction of labour for improving birth outcomes for women at or beyond term' in which is concluded that a policy of induction of labour is associated with fewer adverse perinatal outcome and fewer Caesarean sections. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02666138183022
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http://dx.doi.org/10.1016/j.midw.2018.07.011DOI Listing
November 2018
22 Reads

A Liftless Intervention to Prevent Preterm Birth and Low Birthweight Among Pregnant Ghanaian Women: Protocol of a Stepped-Wedge Cluster Randomized Controlled Trial.

JMIR Res Protoc 2018 Aug 23;7(8):e10095. Epub 2018 Aug 23.

Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland.

Background: Preterm birth (PTB) is a leading cause of infant morbidity and mortality worldwide. Every year, 20 million babies are born with low birthweight (LBW), about 96% of which occur in low-income countries. Despite the associated dangers, in about 40%-50% of PTB and LBW cases, the causes remain unexplained. Read More

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http://www.researchprotocols.org/2018/8/e10095/
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http://dx.doi.org/10.2196/10095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127499PMC
August 2018
12 Reads

Developmental outcome in a group of twins: Relation to perinatal factors and general movements.

Eur J Paediatr Neurol 2018 Jul 20;22(4):682-689. Epub 2018 Apr 20.

Department of Neonatology, Division of Paediatrics, University Medical Centre Ljubljana, Bohoriceva 20, 1000, Ljubljana, Slovenia. Electronic address:

Background: The quality of general movements (GMs) has proven to have predictive value for the developmental outcome, but this has not yet been studied in twins.

Aims: Our aim was to analyse the quality of GMs and neurological and developmental outcome in relation to the gestational age (GA), mode of conception and other perinatal risk factors in a group of twins.

Study Design: The documentation of twins referred for follow-up in the period from 1998 to 2016 was studied retrospectively. Read More

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http://dx.doi.org/10.1016/j.ejpn.2018.04.006DOI Listing
July 2018
5 Reads

Evaluating The Impact of Risk Factors on Birth Weight and Gestational Age: A Multilevel Joint Modeling Approach.

Int J Fertil Steril 2018 Jul 18;12(2):106-113. Epub 2018 Mar 18.

Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: Abnormalities in birth weight and gestational age cause several adverse maternal and infant outcomes. Our study aims to determine the potential factors that affect birth weight and gestational age, and their association.

Materials And Methods: We conducted this cross-sectional study of 4415 pregnant women in Tehran, Iran, from July 6-21, 2015. Read More

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http://dx.doi.org/10.22074/ijfs.2018.5330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936606PMC
July 2018
3 Reads

Preterm Birth and Gestational Length in Four Race-Nativity Groups, Including Somali Americans.

Obstet Gynecol 2018 02;131(2):281-289

Center for Perinatal Research, the Research Institute at Nationwide Children's Hospital, the Departments of Obstetrics and Gynecology and Pediatrics and the College of Public Health, The Ohio State University, and Research Information Solutions and Innovation (RISI), the Research Institute at Nationwide Children's Hospital, Columbus, and Cincinnati Children's Hospital Medical Center, Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati, Ohio.

Objective: To compare preterm birth rates and gestational length in four race-nativity groups including Somali Americans.

Methods: Using a retrospective cohort study design of Ohio birth certificates, we analyzed all singleton births between 2000 and 2015 from four groups of women categorized as U.S. Read More

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http://dx.doi.org/10.1097/AOG.0000000000002427DOI Listing
February 2018
8 Reads

Immediate perinatal outcomes of postterm deliveries.

J Matern Fetal Neonatal Med 2018 Jan 4:1-6. Epub 2018 Jan 4.

c Department of Obstetrics and Gynecology , Soroka University Medical Center, Ben-Gurion University of the Negev , Beer-Sheva , Israel.

Objective: To investigate whether postterm pregnancy (≥42 0/7 weeks' gestation) increases the risk for adverse perinatal outcome.

Study Design: In this population based cohort study, all singleton deliveries occurring between 1991 and 2014 in a tertiary medical center were included. Pregnancy and perinatal outcomes were compared between postterm and term deliveries (37 0/7 to 41 6/7 weeks' gestation). Read More

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http://dx.doi.org/10.1080/14767058.2017.1420773DOI Listing
January 2018
6 Reads

Gestational age and childhood leukemia: A meta-analysis of epidemiologic studies.

Hematology 2018 Jun 3;23(5):253-262. Epub 2017 Nov 3.

a Department of Occupational and Environmental Health, School of Health Sciences , Wuhan University , Wuhan , People's Republic of China.

Objective: An increasing amount of evidence shows that childhood leukemia is initiated in utero. Birth characteristics initiated in utero, such as gestational age, may play a role in leukemogenesis. The purpose of our meta-analysis is to explore the association between gestational age and childhood leukemia. Read More

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http://dx.doi.org/10.1080/10245332.2017.1396056DOI Listing
June 2018
3 Reads

Induction of labour: clinical predictive factors for success and failure.

J Obstet Gynaecol 2018 Apr 23;38(3):352-358. Epub 2017 Oct 23.

a Department of Molecular and Developmental Medicine , University of Siena , Siena , Italy.

Induction of labour (IOL) is a widely-used practice in obstetrics. Our aim was to evaluate predictors of vaginal delivery in postdate pregnancies induced with prostaglandins. We conducted a retrospective cross-sectional study with analytic component. Read More

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http://dx.doi.org/10.1080/01443615.2017.1361388DOI Listing
April 2018
4 Reads

Perinatal complications in patients with unisutural craniosynostosis: An international multicentre retrospective cohort study.

J Craniomaxillofac Surg 2017 Nov 19;45(11):1809-1814. Epub 2017 Aug 19.

University of Gothenburg, The Sahlgrenska Academy, Institute of Clinical Sciences, Department of Plastic Surgery, Sahlgrenska University Hospital, Gröna Straket 8, 413 45, Goteborg, Sweden.

Purpose: Craniosynostosis may lead to hampered fetal head molding and birth complications. To study the interaction between single suture craniosynostosis and delivery complications, an international, multicentre, retrospective cohort study was performed.

Materials And Methods: All infants born between 2006 and 2012 in the Netherlands and Sweden with sagittal or metopic suture synostosis were included. Read More

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http://dx.doi.org/10.1016/j.jcms.2017.08.012DOI Listing
November 2017
43 Reads

Surge of immune cell formation at birth differs by mode of delivery and infant characteristics-A population-based cohort study.

PLoS One 2017 14;12(9):e0184748. Epub 2017 Sep 14.

Division of Pediatrics, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.

Background: Birth by cesarean section is associated with increased risks of immune disorders. We tested whether establishment of immune function at birth relates to mode of delivery, taking other maternal and infant characteristics into account.

Methods And Findings: Using a prospectively collected database, we retrieved information on maternal and infant characteristics of 6,014 singleton infants delivered from February to April 2014 in Stockholm, Sweden, with gestational age ≥35 weeks, Apgar scores ≥7, and without congenital malformations or any neonatal morbidity. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184748PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599043PMC
October 2017
3 Reads

Prevalence of Autism Spectrum Disorders with and without Intellectual Disability by Gestational Age at Birth in the Stockholm Youth Cohort: a Register Linkage Study.

Paediatr Perinat Epidemiol 2017 11 12;31(6):586-594. Epub 2017 Sep 12.

Centre for Women's Mental Health, Manchester Academic Health Sciences Centre, Institute of Brain Behaviour and Mental Health, University of Manchester, Manchester, UK.

Background: Preterm birth has been linked to increased risk of autism spectrum disorders (ASD), but how this risk changes with gestational age at birth has not been well characterised, especially with regard to co-occurring intellectual disability (ID).

Methods: Register-based cohort study of singleton births in 1984-2007 in Stockholm County, Sweden (N total: 480 728; n ASD: 10 025). We assessed overall and sex-specific, gestational week-specific prevalence estimates and risk ratios of ASD with and without ID. Read More

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http://dx.doi.org/10.1111/ppe.12413DOI Listing
November 2017
32 Reads

Validation of maternal reported pregnancy and birth characteristics against the Medical Birth Registry of Norway.

PLoS One 2017 4;12(8):e0181794. Epub 2017 Aug 4.

Dept. of Clinical Science, University of Bergen, Bergen, Norway.

Studies using mothers' self-reported information on birth and pregnancy characteristics are common, but the validity of such data is uncertain. We evaluated questionnaire data from the RHINE III study on reproductive health provided by 715 mothers from Bergen, Norway, about their 1629 births between 1967 and 2010, using the Medical Birth Registry of Norway (MBRN) as gold standard. Validity of dichotomous variables (gender, preterm birth [<37 weeks' gestation], postterm birth [>42 weeks' gestation], induction of labour, forceps delivery, vacuum delivery, caesarean section, were assessed by sensitivity, specificity, positive and negative predictive values (PPV and NPV) and Cohen's kappa. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181794PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544234PMC
October 2017
5 Reads

A mouse model of antepartum stillbirth.

Am J Obstet Gynecol 2017 10 12;217(4):443.e1-443.e11. Epub 2017 Jun 12.

Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Background: Many stillbirths of normally formed fetuses in the third trimester could be prevented via delivery if reliable means to anticipate this outcome existed. However, because the etiology of these stillbirths is often unexplained and although the underlying mechanism is presumed to be hypoxia from placental insufficiency, the placentas often appear normal on histopathological examination. Gestational age is a risk factor for antepartum stillbirth, with a rapid rise in stillbirth rates after 40 weeks' gestation. Read More

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http://dx.doi.org/10.1016/j.ajog.2017.06.009DOI Listing
October 2017
40 Reads

Perspectives on risk: Assessment of risk profiles and outcomes among women planning community birth in the United States.

Birth 2017 09 22;44(3):209-221. Epub 2017 Mar 22.

School of Medicine, University of New Mexico, Albuquerque, NM, USA.

Background: There is little agreement on who is a good candidate for community (home or birth center) birth in the United States.

Methods: Data on n=47 394 midwife-attended, planned community births come from the Midwives Alliance of North America Statistics Project. Logistic regression quantified the independent contribution of 10 risk factors to maternal and neonatal outcomes. Read More

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http://dx.doi.org/10.1111/birt.12288DOI Listing
September 2017
14 Reads

Comparison of Amniotic Fluid Cytokine Levels in Postterm and Term Pregnancy: a Prospective Study.

Clin Lab 2017 Feb;63(2):235-240

Background: To evaluate amniotic fluid pro- and anti-inflammatory cytokine levels in women with postterm and term pregnancies in labor and not in labor.

Methods: The study involved three groups: postterm (Group 1, n = 29), term in labor (Group 2, n = 28), and control (Group 3, n = 30). All groups were compared with respect to age, gravidity, parity, obstetric history, gestation week, cervical dilatation and effacement, maternal serum C-reactive protein and white cell count, amniotic interleukin 4, 6, and 10 levels, birthweight, and cord blood pH. Read More

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http://dx.doi.org/10.7754/Clin.Lab.2016.160711DOI Listing
February 2017
7 Reads

Randomized clinical trial between hourly titrated and 2 hourly static oral misoprostol solution for induction of labor.

Am J Obstet Gynecol 2017 Apr 14;216(4):405.e1-405.e6. Epub 2016 Dec 14.

Department of Obstetrics and Gynecology, King Abdulaziz University, Jeddah, Saudi Arabia.

Background: Misoprostol is an effective agent for the induction of labor. Existing guidelines recommend oral misoprostol solution 25 μg every 2 hours. However, more research is required to optimize the use of oral misoprostol solution for the induction of labor. Read More

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http://dx.doi.org/10.1016/j.ajog.2016.11.1054DOI Listing
April 2017
12 Reads

Lower accuracy in prediction of delivery date in Stockholm County following introduction of new guidelines.

Acta Obstet Gynecol Scand 2017 Feb 7;96(2):223-232. Epub 2017 Jan 7.

Department of Clinical Cancer Epidemiology, Karolinska Institute, Stockholm, Sweden.

Introduction: In Stockholm County, new guidelines for predicting the day of delivery were introduced in 2010. Recent clinical use has indicated that the predictive quality might be suboptimal. This study compares the accuracy of three equations applied during the first (crown-rump length or bi-parietal diameter) and second trimesters (bi-parietal diameter or bi-parietal diameter combined with femur length). Read More

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http://dx.doi.org/10.1111/aogs.13061DOI Listing
February 2017
6 Reads

Oregon's Hard-Stop Policy Limiting Elective Early-Term Deliveries: Association With Obstetric Procedure Use and Health Outcomes.

Obstet Gynecol 2016 12;128(6):1389-1396

Departments of Obstetrics and Gynecology and Public Health & Preventive Medicine, Oregon Health & Science University, Providence Health & Services, Legacy Health, Kaiser Permanente, Northwest Region, and the March of Dimes, Portland, Oregon; and the Center for Health Systems Research, National Institute of Public Health, Cuernavaca, Mexico.

Objective: To evaluate the association of Oregon's hard-stop policy limiting early elective deliveries (before 39 weeks of gestation) and the rate of elective early-term inductions and cesarean deliveries and associated maternal-neonatal outcomes.

Methods: This was a population-based retrospective cohort study of Oregon births between 2008 and 2013 using vital statistics data and multivariable logistic regression models. Our exposure was the Oregon hard-stop policy, defined as the time periods prepolicy (2008-2010) and postpolicy (2012-2013). Read More

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http://dx.doi.org/10.1097/AOG.0000000000001737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121072PMC
December 2016
21 Reads

Body Mass Index and the Spontaneous Onset of Parturition.

Obstet Gynecol 2016 11;128(5):1033-1038

Departments of Obstetrics and Gynecology, University of Colorado, School of Medicine, Aurora, and Denver Health Medical Center and the Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Denver, Denver, Colorado.

Objective: To investigate the relationship between body mass index (BMI) and the onset of parturition throughout gestation.

Methods: This was a secondary analysis of the Maternal-Fetal Medicine Units Network Preterm Prediction Study. Time-to-spontaneous-birth-event (ie, "survival") methods were used to study the association of BMI with the timing of spontaneous onset of labor throughout gestation with indicated births censored at delivery. Read More

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http://pdfs.journals.lww.com/greenjournal/2016/11000/Body_Ma
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http://dx.doi.org/10.1097/AOG.0000000000001678DOI Listing
November 2016
5 Reads

Impact of HIGH BMI on Pregnancy: Maternal and Foetal Outcome.

J Obstet Gynaecol India 2016 Oct 13;66(Suppl 1):192-7. Epub 2016 Jan 13.

Department of Obstetrics and Gynaecology, Government Medical College, Aurangabad, India.

Aim And Objectives: To review the effects of obesity (BMI > 30) on antepartum risk/intrapartum risk. To study neonatal outcome of pregnant women with raised BMI.

Material Method: BMI of 500 pregnant women booked before 12 weeks calculated and categorised as normal, overweight, obese and morbidly obese at GMCH, Aurangabad. Read More

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http://dx.doi.org/10.1007/s13224-015-0825-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016433PMC
October 2016
8 Reads

Clinical characteristics and pregnancy outcomes of Syrian refugees: a case-control study in a tertiary care hospital in Istanbul, Turkey.

Arch Gynecol Obstet 2017 Jan 2;295(1):45-50. Epub 2016 Sep 2.

Department of Obstetrics and Gynecology, Sisli Hamidiye Etfal Training and Research Hospital, Halaskargazi caddesi, Etfal sokak, 34360, Sisli, Istanbul, Turkey.

Purpose: We aimed to compare the clinical characteristics and pregnancy outcomes in women who are Syrian refugees and Turkish women who are non-refugees at a maternity center in Istanbul, Turkey.

Methods: A total of 600 singleton pregnancies who delivered at Sisli Hamidiye Etfal Training and Research Hospital were included in the study. Demographic data, obstetrical history, clinical findings, obstetrical and neonatal outcomes were compared between 300 Syrian refugees and 300 control patients. Read More

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http://dx.doi.org/10.1007/s00404-016-4188-5DOI Listing
January 2017
15 Reads

Induction of Labour in Late and Postterm Pregnancies and its Impact on Maternal and Neonatal Outcome.

Geburtshilfe Frauenheilkd 2016 Jul;76(7):793-798

University Hospital of Cologne, Department of Obstetrics and Gynecology, Cologne, Germany.

Introduction: This study aimed to determine the effects of induction of labour in late-term pregnancies on the mode of delivery, maternal and neonatal outcome.

Methods: We retrospectively analyzed deliveries between 2000 and 2014 at the University Hospital of Cologne. Women with a pregnancy aged between 41 + 0 to 42 + 6 weeks were included. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-107672
Publisher Site
http://dx.doi.org/10.1055/s-0042-107672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001572PMC
July 2016
3 Reads

[Posterm pregnancy].

Authors:
A Měchurová

Ceska Gynekol 2016 04;81(2):98-103

Unlabelled: This review presents the up-to-date information from published resources on the issue of Posterm pregnancy (Medline, Cochrane Database, ACOG, RCOG, SOGC) and complements the presented guidelines. The most of resources are using the term "postterm pregnancy" for pregnancy reaching or exceeding 42+0 weeks and days of gestation, while late pregnancy is defined as a period in between 41+0 and 41+6.The exact determination of gestational age is necessary for exact diagnosis and appropriate management of late and postterm pregnancy, because these pregnancies have increased risk of perinatal morbidity and mortality. Read More

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April 2016
11 Reads

Clinical characteristics and prognosis of 272 postterm choriocarcinoma patients at Peking Union Medical College Hospital: a retrospective cohort study.

BMC Cancer 2016 06 2;16:347. Epub 2016 Jun 2.

Departments of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, 100730, Beijing, People's Republic of China.

Background: The objective of our study was to investigate the clinical characteristics and prognosis of postterm choriocarcinoma patients at Peking Union Medical College Hospital within the past 30 years.

Methods: The clinical characteristics and pertinent follow-up data of 272 patients with postterm choriocarcinoma diagnosed from December 1985 through December 2014 in our hospital were reviewed. The clinical characteristics of two cohorts cut off at 2006 were compared using χ (2) tests. Read More

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http://dx.doi.org/10.1186/s12885-016-2383-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890243PMC
June 2016
17 Reads

Reduced Breastfeeding Rates in Firstborn Late Preterm and Early Term Infants.

Breastfeed Med 2016 Apr 23;11:119-25. Epub 2016 Mar 23.

2 Department of Obstetrics and Gynecology, Penn State College of Medicine , Hershey, Pennsylvania.

Objectives: The primary objective was to determine the rate of breastfeeding by gestational age reported by new mothers 1 month postpartum, with particular focus on early term newborns (37-38(6)/7 weeks).

Materials And Methods: Three thousand six primiparous women aged 18-36 years were interviewed during their third trimester and again 1 month postpartum. Logistic regression analysis was used to model the association between gestational age and breastfeeding 1 month postpartum among those who reported that they planned to breastfeed, controlling for potentially confounding variables. Read More

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http://dx.doi.org/10.1089/bfm.2015.0122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827273PMC
April 2016
14 Reads

When should pregnancies that extended beyond term be induced?

J Matern Fetal Neonatal Med 2017 Jan 14;30(2):219-223. Epub 2016 Apr 14.

a Department of Obstetrics and Gynecology and.

Objective: To compare maternal and neonatal outcomes associated with a policy for induction of labor at ≥ 41 versus at ≥42 weeks'.

Study Design: Retrospective cohort study of a 2 years' period before and after policy change from induction of labor at ≥ 42 gestational weeks' versus ≥41 gestational weeks.

Results: During the 41-policy period (N = 968), the induction rate was higher, 60% versus 40% (p < 0. Read More

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http://dx.doi.org/10.3109/14767058.2016.1169520DOI Listing
January 2017
9 Reads

Study protocol of SWEPIS a Swedish multicentre register based randomised controlled trial to compare induction of labour at 41 completed gestational weeks versus expectant management and induction at 42 completed gestational weeks.

BMC Pregnancy Childbirth 2016 Mar 7;16:49. Epub 2016 Mar 7.

Gothenburg University, Perinatal centre, Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, Sahlgrenska University Hospital, East, S-416 85, Gothenburg, Sweden.

Background: Observational data shows that postterm pregnancy (≥42 gestational weeks, GW) and late term pregnancy (≥41 GW), as compared to term pregnancy, is associated with an increased risk for adverse outcome for the mother and infant. Standard care in many countries is induction of labour at 42 GW. There is insufficient scientific support that induction of labour at 41 GW, as compared with expectant management and induction at 42 GW will reduce perinatal mortality and morbidity without an increase in operative deliveries, negative delivery experiences or higher costs. Read More

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http://dx.doi.org/10.1186/s12884-016-0836-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782290PMC
March 2016
15 Reads

A comparison between amniotic fluid index and the single deepest vertical pocket technique in predicting adverse outcome in prolonged pregnancy.

J Prenat Med 2015 Jan-Jun;9(1-2):12-5

Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy.

Objective: to compare perinatal outcome in induced postterm pregnancies with normal amniotic volume and in patients with prolonged pregnancy undergone induction for oligohydramnios, evaluated by two different ultrasonographic methods.

Methods: amniotic fluid volume was measured, using Single Deepest Vertical Pocket (SDVP) and Amniotic Fluid Index (AFI), in 961 singleton uncomplicated prolonged pregnancies. In 109 of these patients, hospitalization was planned for induction of labor, during or after 42 weeks of gestation, for oligohydramnios, postterm pregnancy and other indications in 47, 51 and 11 cases, respectively. Read More

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http://dx.doi.org/10.11138/jpm/2015.9.1.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747565PMC
February 2016
7 Reads

Preeclampsia, biomarkers, syncytiotrophoblast stress, and placental capacity.

Am J Obstet Gynecol 2015 Oct;213(4 Suppl):S9.e1, S9-11

Faculty of Medicine, University of Oslo, and Department of Obstetrics and Department of Gynecology, Oslo University Hospital, Oslo, Norway.

The maternal syndrome of preeclampsia is mediated by dysfunctional syncytiotrophoblast (STB). When this is stressed by uteroplacental malperfusion, its signaling to the mother changes, as part of a highly coordinated stress response. The STB signals are both proinflammatory and dysangiogenic such that the preeclamptic mother has a stronger vascular inflammatory response than normal, with an antiangiogenic bias. Read More

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http://dx.doi.org/10.1016/j.ajog.2015.08.003DOI Listing
October 2015
3 Reads

Preterm Birth: A Prominent Risk Factor for Low Apgar Scores.

Biomed Res Int 2015 27;2015:978079. Epub 2015 Aug 27.

Department of Obstetrics and Gynecology, and Department of Clinical and Experimental Medicine, Linköping University, 581 83 Linköping, Sweden.

Objective: To determine predictive risk factors for Apgar scores < 7 at 5 minutes at two hospitals providing tertiary care and secondary care, respectively.

Methods: A retrospective registry cohort study of 21126 births (2006-2010) using data from digital medical records. Risk factors were analyzed by logistic regression analyses. Read More

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http://dx.doi.org/10.1155/2015/978079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564604PMC
July 2016
3 Reads

Physical fitness, serum relaxin and duration of gestation.

BMC Pregnancy Childbirth 2015 Aug 14;15:168. Epub 2015 Aug 14.

Department of Public Health and Caring Sciences, Uppsala University, Uppsala, SE-75122, Sweden.

Background: Women are recommended to perform regular exercise during pregnancy but the impact of physical fitness on duration of gestation and miscarriage is inconsistent. In addition, a dose-response relation between the amount of weekly exercise and increased risk of miscarriage in early pregnancy has been observed. Previous studies have mostly used an epidemiologic method. Read More

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http://dx.doi.org/10.1186/s12884-015-0607-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536895PMC
August 2015
9 Reads

Recurrence rate and outcome of postterm pregnancy, a national cohort study.

Eur J Obstet Gynecol Reprod Biol 2015 Oct 9;193:70-4. Epub 2015 Jun 9.

Academic Medical Center, University of Amsterdam, Department of Obstetrics and Gynaecology, Amsterdam, The Netherlands.

Objective: To assess the recurrence rate of postterm delivery (gestational age at or beyond 42+0 weeks or 294 days) and to describe maternal and perinatal outcomes after previous postterm delivery.

Study Design: From the longitudinal linked Netherlands Perinatal Registry database, we selected all singleton primiparous women who delivered between 37+0 and 42+6 weeks with a subsequent singleton pregnancy from 1999 to 2007. We excluded congenital abnormalities. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2015.05.021DOI Listing
October 2015
10 Reads

Immigrants from conflict-zone countries: an observational comparison study of obstetric outcomes in a low-risk maternity ward in Norway.

BMC Pregnancy Childbirth 2015 Aug 5;15:163. Epub 2015 Aug 5.

University of Oslo, Faculty of Medicine, Institution of Clinical Medicine, P.O. Box 1171, Blindern, 0318, Oslo, Norway.

Background: Immigrants have higher risks for some adverse obstetric outcomes. Furthermore, refugees are reported to be the most vulnerable group. This study compared obstetric outcomes between immigrant women originating from conflict-zone countries and ethnic Norwegians who gave birth in a low-risk setting. Read More

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http://dx.doi.org/10.1186/s12884-015-0603-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523905PMC
August 2015
13 Reads

Risk of spontaneous abortion and other pregnancy outcomes in 15-25 year old women exposed to human papillomavirus-16/18 AS04-adjuvanted vaccine in the United Kingdom.

Vaccine 2015 Nov 21;33(48):6884-91. Epub 2015 Jul 21.

University of California San Diego School of Medicine, USA.

Background: We assessed the risk of spontaneous abortion (SA) after inadvertent exposure to HPV-16/18-vaccine during pregnancy using an observational cohort design.

Methods: The study population included women aged 15-25 years registered with the Clinical Practice Research Datalink General Practice OnLine Database in the United Kingdom (UK), who received at least one HPV-16/18-vaccine dose between 1st September 2008 and 30th June 2011. Exposed women had the first day of gestation between 30 days before and 45 days (90 days for the extended exposure period) after any HPV-16/18-vaccine dose. Read More

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http://dx.doi.org/10.1016/j.vaccine.2015.07.024DOI Listing
November 2015
24 Reads

Toll-Like Receptor 4 Is an Essential Upstream Regulator of On-Time Parturition and Perinatal Viability in Mice.

Endocrinology 2015 Oct 7;156(10):3828-41. Epub 2015 Jul 7.

Robinson Research Institute and School of Medicine (H.H.W., C.D., P.Y.C., M.R.H., L.M.M., S.A.R.), University of Adelaide, Adelaide SA 5005, Australia; Chemical Biology Research Branch (K.C.R.), National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland 20892; and Departments of Obstetrics and Gynecology, Pediatrics and Physiology (D.M.O.), University of Alberta, Edmonton, Canada AB TG62S2.

An inflammatory response is instrumental in the physiological process of parturition but the upstream signals initiating inflammation are undefined. Because endogenous ligands for Toll-like receptor 4 (TLR4) are released in late gestation, we hypothesized that on-time labor requires TLR4 signaling, to trigger a cytokine and leukocyte response and accelerate the parturition cascade. In pregnant TLR4-deficient (Tlr4-/-) mice, average gestation length was extended by 13 hours and increased perinatal mortality was seen compared with wild-type controls. Read More

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http://dx.doi.org/10.1210/EN.2015-1089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588813PMC
October 2015
6 Reads

Diagnosis, antenatal surveillance and management of prolonged pregnancy: current perspectives.

Minerva Ginecol 2015 Aug;67(4):365-73

Department of Medical Surgical Specialties, Gynecology and Obstetrics Section, University of Catania, Catania, Italy -

Prolonged pregnancy is defined as a pregnancy that extends beyond 42 weeks of gestation (294 days) from the first day of the last normal menstrual period. An accurate estimation of the 'natural' incidence of prolonged pregnancy would require meticulous early pregnancy dating. The use of ultrasound to establish gestational age reduces the number of pregnancies that are classified as prolonged. Read More

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August 2015
4 Reads

Midpregnancy Cervical Length in Nulliparous Women and its Association with Postterm Delivery and Intrapartum Cesarean Delivery.

Am J Perinatol 2016 Jan 26;33(1):40-6. Epub 2015 Jun 26.

Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands.

Objective: To evaluate the association between midpregnancy cervical length and postterm delivery and cesarean delivery during labor.

Study Design: In a multicenter cohort study, cervical length was measured in low-risk singleton pregnancies between 16 and 22 weeks of gestation. From this cohort, we identified nulliparous women who delivered beyond 34 weeks and calculated cervical length quartiles. Read More

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http://dx.doi.org/10.1055/s-0035-1556067DOI Listing
January 2016
1 Read

Pregnancy risks associated with obesity.

Obstet Gynecol Clin North Am 2015 Jun;42(2):335-53

Department of Obstetrics and Gynecology, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA. Electronic address:

Obesity has increased dramatically in the United States over the last several decades, with approximately 40% of pregnant women now considered overweight or obese. Obesity has been shown to be associated with numerous poor pregnancy outcomes, including increased rates of preeclampsia, gestational diabetes, fetal macrosomia, stillbirth, postterm pregnancy, and increased rates of cesarean delivery. Many of these complications have been found to increase even further with increasing body mass index in a dose-response fashion. Read More

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http://dx.doi.org/10.1016/j.ogc.2015.01.008DOI Listing
June 2015
13 Reads

Maternal health and pregnancy outcomes comparing migrant women born in humanitarian and nonhumanitarian source countries: a retrospective, observational study.

Birth 2015 Jun 11;42(2):116-24. Epub 2015 Apr 11.

Monash Centre for Health Research and Implementation, Monash University Clayton, Victoria, Australia.

Background: The relationship between migration and pregnancy outcomes is complex, with little insight into whether women of refugee background have greater risks of adverse pregnancy outcomes than other migrant women. This study aimed to describe maternal health, pregnancy care, and pregnancy outcomes among migrant women from humanitarian and nonhumanitarian source countries.

Methods: Retrospective, observational study of singleton births, at a single maternity service in Australia 2002-2011, to migrant women born in humanitarian source countries (HSCs, n = 2,713) and non-HSCs (n = 10,606). Read More

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http://dx.doi.org/10.1111/birt.12159DOI Listing
June 2015
8 Reads

Induction of Labor and Cesarean: What is the True Relationship?

Clin Obstet Gynecol 2015 Jun;58(2):269-81

*Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Maternal-Fetal Medicine, Brigham and Women's Hospital, Boston, Massachusetts †Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, Oregon.

It is a commonly held belief that labor induction increases the risk of cesarean delivery; women who are induced are at higher risk of cesarean as compared with those in spontaneous labor. This comparison group is inaccurate, however, as women and providers cannot choose spontaneous labor as the alternative to labor induction. With expectant management, spontaneous labor may occur, but as gestation advances, pregnancy complications may occur, or women may progress postterm requiring induction at a later gestation. Read More

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http://dx.doi.org/10.1097/GRF.0000000000000112DOI Listing
June 2015
7 Reads

Higher risk for adverse obstetric outcomes among immigrants of African and Asian descent: a comparison study at a low-risk maternity hospital in Norway.

Birth 2015 Jun 6;42(2):132-40. Epub 2015 Apr 6.

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

Background: Immigrants have higher risks for some adverse obstetric outcomes, and 40 percent of women giving birth at the low-risk maternity ward in Baerum Hospital, Norway, are immigrants. This study compared obstetric outcomes between immigrants and ethnic Norwegians giving birth in a low-risk setting.

Methods: This was a population-based study linking the Medical Birth Registry of Norway to Statistics Norway. Read More

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http://dx.doi.org/10.1111/birt.12165DOI Listing
June 2015
2 Reads

Postterm, postdates, and prolonged pregnancy: need for simplification of terminology.

Authors:
Shilpi Chabra

Obstet Gynecol 2015 Apr;125(4):980-1

Department of Pediatrics, Division of Neonatology, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1097/AOG.0000000000000763DOI Listing
April 2015
5 Reads

Preterm and postterm birth in immigrant- and Swedish-born parents: a population register-based study.

Eur J Epidemiol 2015 May 17;30(5):435-47. Epub 2015 Feb 17.

Centre for Health Equity Studies (CHESS), Stockholm University/Karolinska Institutet, Stockholm, Sweden,

Ethnic minorities/immigrant groups tend to have increased risk for preterm birth. Less is known about this risk in diverse immigrant groups, couples of mixed ethnic-origin and in relation to duration of residence. Data from the Swedish Medical Birth Register on 1,028,303 mothers who gave birth to 1,766,026 singleton live born infants (1982-2002), was linked to the Education and Total Population Registers. Read More

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http://dx.doi.org/10.1007/s10654-014-9986-0DOI Listing
May 2015
3 Reads

Visfatin/Nampt and SIRT1: Roles in Postterm Delivery in Pregnancies Associated With Obesity.

Reprod Sci 2015 Aug 10;22(8):1028-36. Epub 2015 Feb 10.

Department of Obstetrics, Gynecology, and Women's Health, University of Hawaii, John A. Burns School of Medicine, Honolulu, HI, USA.

Visfatin is both a systemic adipocytokine and the cytosolic enzyme, nicotinamide phosphoribosyl transferase (Nampt). This is a longevity protein, which extends the lifespan of human cells by activating sirtuin 1 (SIRT1). In this study, we sought a role for these proteins in obese pregnant women, who experience more postterm deliveries. Read More

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http://dx.doi.org/10.1177/1933719115570908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933096PMC
August 2015
2 Reads

Induction of labor: update and review.

J Midwifery Womens Health 2014 Nov-Dec;59(6):606-15

Rates of labor induction in the United States have more than doubled in the past 2 decades. Trends of indications and risk factors related to induction of labor are also increasing. Professional organizations such as the American College of Obstetricians and Gynecologists and The Joint Commission have taken steps to discourage elective induction of labor prior to 39 weeks' gestation and have created new definitions of early-term, full-term, late-term, and postterm gestation to guide clinicians in the timing of birth for specified indications. Read More

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http://dx.doi.org/10.1111/jmwh.12255DOI Listing
June 2016
18 Reads

Trends in spontaneous and indicated preterm delivery among singleton gestations in the United States, 2005-2012.

Obstet Gynecol 2014 Dec;124(6):1069-74

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, and the Department of Obstetrics and Gynecology, College of Physicians and Surgeons, and the Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.

Objective: For the first time in decades, the rate of U.S. preterm delivery has declined consistently since 2005. Read More

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http://dx.doi.org/10.1097/AOG.0000000000000546DOI Listing
December 2014
2 Reads

Common questions about late-term and postterm pregnancy.

Am Fam Physician 2014 Aug;90(3):160-5

HealthPartners Institute for Education and Research, Bloomington, MN, USA.

Pregnancy is considered late term from 41 weeks, 0 days' to 41 weeks, 6 days' gestation, and postterm at 42 weeks' gestation. Early dating of the pregnancy is important for accurately determining when a pregnancy is late- or postterm, and first-trimester ultrasonography should be performed if clinical dating is uncertain. Optimal management of a low-risk, late-term pregnancy should consider maternal preference and balance the benefits and risks of induction vs. Read More

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August 2014
9 Reads