898 results match your criteria Postpolio Syndrome


Effectiveness of Intravenous Immunoglobulin for Management of Pain in Patients with Postpolio Syndrome.

Pain Res Manag 2021 20;2021:6637705. Epub 2021 Mar 20.

Department of Physical Medicine and Rehabilitation, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.

Objective: Many patients with postpolio syndrome (PPS) experience pain. In this study, we aimed to review previous studies to investigate the effectiveness of intravenous immunoglobulin (IVIG) for managing pain in patients with PPS. We performed a narrative review. Read More

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Imaging as an alternate diagnostic modality in a presumptive case of abdominopelvic TB in a COVID-19 patient.

BMJ Case Rep 2021 Mar 2;14(3). Epub 2021 Mar 2.

Obstetrics and Gynaecology, Jawaharlal Institute of Postgraduate Medical Education, Puducherry, India.

A 30-year-old, multiparous widow, with postpolio residual paralysis, presented with complaints of dull aching abdominal pain for 15 days. Ultrasound showed a mixed echogenic right adnexal mass with free fluid in the pelvis and abdomen. CT abdomen and pelvis revealed partially defined peripherally enhancing collection in lower abdomen and right adnexa suggestive of tubo-ovarian abscess. Read More

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Prevalence and Effect of Obesity on Mobility According to Different Criteria in Polio Survivors.

Am J Phys Med Rehabil 2021 03;100(3):250-258

From the Department of Rehabilitation Medicine, Seongnam Citizens Medical Center, Seongnam-si (K-HS); Department of Rehabilitation Medicine, Dongmasan General Hospital, Masan-Si (JHL); Department of Physical Medicine and Rehabilitation, Soonchunhyang University Bucheon Hospital, Bucheon-si (S-YL); and Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-si, Korea (JYL, J-YL).

Objective: Obesity is a major and functionally important problem in polio survivors. The aim of this study was to investigate the prevalence of obesity using body mass index and percentage body fat in polio survivors and to analyze the relationship between obesity and mobility.

Design: Eighty-four polio survivors were included. Read More

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Postpoliomyelitis Syndrome and Reversal With Sugammadex: A Case Report.

AANA J 2020 Oct;88(5):380-382

is an adjunct associate professor of anesthesiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, and University of Cincinnati Medical Center.

Postpolio syndrome (PPS) is a disabling process characterized by progressive muscle weakness and atrophy that typically emerges decades after an initial poliomyelitis infection. Although the exact incidence of PPS is unknown, it is estimated that 25% to 40% of all poliomyelitis survivors are affected. Patients with PPS may have increased sensitivity to numerous anesthetic agents including neuromuscular blocking drugs. Read More

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October 2020

Updated size index valid for both neurogenic and myogenic changes.

Muscle Nerve 2020 12 29;62(6):735-741. Epub 2020 Sep 29.

Department of Clinical Neurophysiology, Institute of Neuroscience, Uppsala University, Uppsala, Sweden.

Background: Size index (SI) is a motor unit potential (MUP) parameter in concentric needle electromyography calculated from amplitude and area/amplitude, which can sensitively discriminate between control and neurogenic MUPs. In this study, we investigated the application of SI to myogenic MUPs based on expanded data.

Methods: MUPs were collected from the biceps brachii (BB) and tibialis anterior (TA) muscles. Read More

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December 2020

Usefulness of Neuromuscular Co-morbidity, Left Bundle Branch Block, and Atrial Fibrillation to Predict the Long-Term Prognosis of Left Ventricular Hypertrabeculation/Noncompaction.

Am J Cardiol 2020 08 13;128:168-173. Epub 2020 May 13.

Krankenanstalt Rudolfstiftung, Wien, Austria.

The prognosis of patients with left ventricular hypertrabeculation/noncompaction (LVHT) is assessed controversially. LVHT is associated with other cardiac abnormalities and with neuromuscular disorders (NMD). Aim of the study was to assess cardiac and neurological findings as predictors of mortality rate in adult LVHT-patients. Read More

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Post-Polio Syndrome Causing Late Onset Respiratory Failure.

Isr Med Assoc J 2020 Jun;22(6):395-396

Department of Internal Medicine C, Shamir Medical Center, Zerifin, Israel.

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Corticomotor Excitability in Two Kinds of Motor Neuron Diseases: A Study on the Patients With Amyotrophic Lateral Sclerosis and Poliomyelitis Survivors.

J Clin Neurophysiol 2020 May 26. Epub 2020 May 26.

Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Purpose: To examine upper motor neuron functions comparatively in patients with amyotrophic lateral sclerosis (ALS) and poliomyelitis survivors using transcranial magnetic stimulation (TMS) methods.

Methods: Single- and paired-pulse TMS with conventional methods and the triple-stimulation technique were performed by recording from the abductor digiti minimi and abductor pollicis brevis muscles in 31 patients with ALS, 18 patients with poliomyelitis survivors, and 21 controls. Nine patients were diagnosed as having postpoliomyelitis syndrome after a 6-month follow-up. Read More

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Longitudinal associations between physical activity, anxiety, and depression in adults with long-term physical disabilities.

Health Psychol 2020 Jun 23;39(6):529-538. Epub 2020 Mar 23.

Department of Rehabilitation Medicine.

Objective: To evaluate the longitudinal associations between self-reported physical activity and anxiety and depression symptom severity in adults with long-term physical disabilities.

Method: A secondary analysis of data from a United States-based longitudinal survey study of community-dwelling adults with 1 of 4 potential long-term physical disabilities (multiple sclerosis, muscular dystrophy, spinal cord injury, postpoliomyelitis syndrome). The first time point (T1) for the current study was completed by 1,594 participants. Read More

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A twelve-week, four-arm, randomized, double-blind, placebo-controlled, phase 2 prospective clinical trial to evaluate the efficacy and safety of an anthroposophic multimodal treatment on chronic pain in outpatients with postpolio syndrome.

Brain Behav 2020 04 11;10(4):e01590. Epub 2020 Mar 11.

Department of Neurology, Universidade Federal de Sao Paulo, São Paulo, Brazil.

Introduction: Chronic pain and fatigue are the main symptoms of postpoliomyelitis syndrome (PPS). This study aimed to evaluate the efficacy and safety of an anthroposophic multimodal treatment for chronic pain in PPS outpatients.

Methods: A twelve-week, four-arm, randomized, double-blind, placebo-controlled, phase 2 prospective clinical trial was designed to compare four groups (n = 48): groups A and B received daily active experimental transdermal gel (ETG) or placebo gel (PTG), respectively; groups C and D received weekly external therapies, art therapies, and neurofunctional reorganization, plus either daily ETG or PTG, respectively. Read More

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Cross-lagged longitudinal analysis of pain intensity and sleep disturbance.

Disabil Health J 2020 07 12;13(3):100908. Epub 2020 Feb 12.

University of Washington, Rehabilitation Medicine, Box 354237, 4907 25th Ave NE, Seattle, WA, 98105, USA. Electronic address:

Background: There is substantial evidence that pain intensity and sleep are related, with findings generally suggesting more support for the influence of sleep on pain intensity than vice versa. However, the strength and direction of the relationship has been found to vary among different populations, with few studies in individuals with chronic physical disabilities.

Objective: Examine the directionality of the sleep and pain relationship in individuals with chronic physical disabilities. Read More

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A very long-term longitudinal follow-up of persons with late effects of polio.

Eur J Phys Rehabil Med 2020 Apr 10;56(2):155-159. Epub 2020 Feb 10.

Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.

Background: As many as 60-80% of persons with a history of polio myelitis develop new symptoms, such as new or increased muscle weakness, muscle and joint pain, and fatigue several decades later, called postpolio syndrome (PPS). This may affect their ability to perform activities of daily living (ADL). It is still unclear if the patient's symptom is getting worse and in that case how much/fast the decline is. Read More

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Kaposi sarcoma in a patient with postpolio syndrome.

Cutis 2019 Nov;104(5):E20-E22

Departments of Radiation Oncology and Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA.

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November 2019

Goal Pursuit, Goal Adjustment, and Pain in Middle-Aged Adults Aging With Physical Disability.

J Aging Health 2019 12;31(10_suppl):214S-240S

University of Washington School of Medicine, Seattle, USA.

Aging with physical disability disrupts one's ability to achieve valued goals due to changes in symptoms and function. It is unclear how to cope optimally in this context. This study examined whether two possible strategies-tenacious goal pursuit (TGP) and flexible goal adjustment (FGA)-were associated with reduced pain interference and depressive symptoms and greater well-being, and protected against pain intensity, and FGA was more protective with increasing age and worse physical function. Read More

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December 2019

Polio and post-polio syndrome in non-Western immigrants: A new challenge for the healthcare system in Norway.

J Rehabil Med 2019 Dec;51(11):861-868

Department of Research, Sunnaas Rehabilitation Hospital, Bjørnemyrveien 11, NO-1450 Nesoddtangen, Norway.

Objective: To explore the health situation and identify specific health challenges in non-Western immigrants with polio in Norway, by comparing their status with Western immigrants with polio and native Norwegians with polio.

Design: A questionnaire covering demographics, polio history, life satisfaction, medical, psychological and social conditions was answered by 1,408 persons with polio, among them 34 immigrants from non-Western countries and 32 immigrants from Western countries.

Results: The non-Western immigrant polio group had a mean age of 46 years, were highly educated, reported high frequency of mental health problems and only one-third was working. Read More

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December 2019

Resilience and Function in Adults With Chronic Physical Disabilities: A Cross-Lagged Panel Design.

Ann Behav Med 2020 04;54(5):297-307

Department of Rehabilitation Medicine, University of Washington, WA, USA.

Background: Resilience is a psychological construct referring to one's positive adaptation in response to adversity. Evidence suggests that resilience may contribute to various function domains in adults with chronic physical disabilities.

Purpose: To test hypothesized temporal associations between resilience and four function domains (anxiety, depression, social role satisfaction, and physical function) in individuals with chronic physical disabilities. Read More

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Postpolio Syndrome: A Review of Lived Experiences of Patients.

Int J Appl Basic Med Res 2019 Jul-Sep;9(3):129-134

Department of Anatomical Sciences, University of Medicine and Health Sciences, Basseterre, St. Kitts and Nevis.

Postpolio syndrome (PPS) refers to a group of conditions that are present in patients, years after recovery from initial acute paralytic poliomyelitis. About 15%-80% of 20 million polio survivors worldwide will experience exacerbation of symptoms which typically appear 15-30 years after the resolution of initial poliomyelitis. Symptoms include new muscle weakness, fatigue, myalgia, joint pain, dysphagia, and difficulty breathing. Read More

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Post-polio Syndrome: More Than Just a Lower Motor Neuron Disease.

Front Neurol 2019 16;10:773. Epub 2019 Jul 16.

Computational Neuroimaging Group, Academic Unit of Neurology, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

Post-polio syndrome (PPS) is a neurological condition that affects polio survivors decades after their initial infection. Despite its high prevalence, the etiology of PPS remains elusive, mechanisms of progression are poorly understood, and the condition is notoriously under-researched. While motor dysfunction is a hallmark feature of the condition, generalized fatigue, sleep disturbance, decreased endurance, neuropsychological deficits, sensory symptoms, and chronic pain are also often reported and have considerable quality of life implications in PPS. Read More

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Experiences of Speaking With Noninvasive Positive Pressure Ventilation: A Qualitative Investigation.

Am J Speech Lang Pathol 2019 07 15;28(2S):784-792. Epub 2019 Jul 15.

Department of Rehabilitation Medicine, University of Washington, Seattle.

Purpose The aim of this study was to describe experiences of speaking with 2 forms of noninvasive positive pressure ventilation (NPPV)-mouthpiece NPPV (M-NPPV) and nasal bilevel positive airway pressure (BPAP)-in people with neuromuscular disorders who depend on NPPV for survival. Method Twelve participants (ages 22-68 years; 10 men, 2 women) with neuromuscular disorders (9 Duchenne muscular dystrophy, 1 Becker muscular dystrophy, 1 postpolio syndrome, and 1 spinal cord injury) took part in semistructured interviews about their speech. All subjects used M-NPPV during the day, and all but 1 used BPAP at night for their ventilation needs. Read More

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Secondary health conditions and social role satisfaction in adults with long-term physical disability.

Health Psychol 2019 May;38(5):445-454

Department of Rehabilitation Medicine, University of Washington.

Objective: Individuals living with physical disability due to early acquired or traumatic conditions often experience a range of psychological and physical health problems that are associated with their condition but are not directly caused by it. Known as "secondary health conditions," these problems can interact with existing functional limitations and other medical comorbidities to limit social participation. The current study assessed the concurrent and longitudinal associations between secondary health conditions, chronic medical comorbidities, and functional limitations, with a PROMIS® measure of social role participation. Read More

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Motor Unit Number Index (MUNIX) as a biomarker of motor unit loss in post-polio syndrome versus needle EMG.

J Electromyogr Kinesiol 2019 Jun 9;46:35-40. Epub 2019 Mar 9.

Department of Neurology, Medical University of Warsaw, 02-097 Warsaw, Banacha 1A str., Poland.

MUNIX method (Motor Unit Number Index) had been not used to assess number of motor neurons in post-polio syndrome in contrary to needle electromyography.

Objectives: To confirm if MUNIX reflects motor unit loss and clinical stage and to assess difference in MUNIX and EMG results between muscles in different stage.

Methods: 132 Muscles (MUNIX) and 96 (EMG) in 12 patients were studied and divided into groups: with normal strength(N), stable weakness and atrophy(S), new weakness and atrophy(W). Read More

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Neurological Symptoms in Danes with a History of Poliomyelitis: Lifelong Follow-Up of Late Symptoms, their Association with Initial Symptoms of Polio, and Presence of Postpolio Syndrome.

Eur Neurol 2018 5;80(5-6):295-303. Epub 2019 Mar 5.

Danish Center for Sleep Medicine, Department of Clinical Neurophysiology, Rigshospitalet, University of Copenhagen, Glostrup, Denmark.

Background: Previous studies suggest that patients with a history of poliomyelitis (PM) later in life experience a variety of symptoms. These studies were carried out in patients who later in life were admitted to hospital or became members of polio societies and may therefore not be representative of all polio patients. Little data have been published concerning patients actually discharged from hospital with a diagnosis of acute paralytic PM. Read More

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Efficacy of Oral Care Provided by Interprofessional Collaboration for a Patient with Esophageal Cancer Associated with Post-polio Syndrome during Neoadjuvant Chemotherapy.

Acta Med Okayama 2019 Feb;73(1):71-76

Dental Hygienist Team, Division of Medical Technology, Okayama University Hospital, Okayama 700-8558, Japan.

Preoperative oral care is helpful to prevent postoperative complications in patients who are undergoing esophagectomy. Here, we report the case of an 81-year-old Japanese man with an upper limb disability caused by post-polio syndrome who was receiving neoadjuvant chemotherapy for esophageal cancer. He had poor oral health status and developed oral complications as a side effect of chemotherapy. Read More

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February 2019

Amyotrophic Lateral Sclerosis and its Mimics/Variants: A Comprehensive Review.

J Clin Imaging Sci 2018 6;8:53. Epub 2018 Dec 6.

Department of Radiology, Advocate Illinois Masonic Medical Center, Chicago, Illinois, USA.

Motor neuron diseases (MNDs) are a debilitating subset of diseases, which result in progressive neuronal destruction and eventual loss of voluntary muscular function. These entities are often challenging to distinguish and accurately diagnose given overlapping clinical pictures and overall rarity. This group of diseases has a high morbidity and mortality rate overall and delineating each type of disease can help guide appropriate clinical management and improve quality of life for patients. Read More

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December 2018

Radiographic and Clinical Outcomes of Surgical Correction of Poliomyelitis-Related Spinal Deformities: A Comparison Among Three Types of Pelvic Instrumentations.

World Neurosurg 2019 Feb 12;122:e1111-e1119. Epub 2018 Nov 12.

Department of Spine Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China. Electronic address:

Background: We compared the clinical and radiographic outcomes of corrective surgery in patients with poliomyelitis-related spinal deformity (PSD) using 3 types of pelvic fixation and investigated the incidence and risk factors for complications.

Methods: We reviewed the data from 42 patients with PSD who had undergone spinopelvic reconstruction at a single institution from 2000 to 2016. Of the 42 patients, 15 had been treated with the Galveston technique, 13 with iliac screw fixation, and 14 with S2-alar-iliac (S2AI) screw fixation. Read More

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February 2019

Psychometric Properties of Three Fatigue Rating Scales in Individuals With Late Effects of Polio.

Ann Rehabil Med 2018 Oct 31;42(5):702-712. Epub 2018 Oct 31.

Department of Health Sciences, Lund University, Lund, Sweden.

Objective: To evaluate the psychometric properties of the Fatigue Severity Scale (FSS), the Fatigue Impact Scale (FIS), and the Multidimensional Fatigue Inventory (MFI-20) in persons with late effects of polio (LEoP). More specifically, we explored the data completeness, scaling assumptions, targeting, reliability, and convergent validity.

Methods: A postal survey including FSS, FIS, and MFI-20 was administered to 77 persons with LEoP. Read More

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October 2018

Sex/gender disparities in health outcomes of individuals with long-term disabling conditions.

Rehabil Psychol 2019 May 8;64(2):221-228. Epub 2018 Oct 8.

Department of Rehabilitation Medicine.

Background: Women with disabling conditions experience health disparities relative to nondisabled women, but few studies have compared women and men with disabling conditions.

Objectives: To investigate gender differences in physical functioning and emotional health among individuals with long-term disabling conditions, that is, neuromuscular disease, multiple sclerosis, postpolio syndrome, or spinal cord injury.

Method: From a mailed survey of 1,862 adults with long-term disabling conditions, we used the 12-item Patient-Reported Outcomes Measurement Information System (PROMIS) physical functioning to assess physical limitations in activities and Patient Health Questionnaire-9 (PHQ-9) for emotional health and severity of secondary conditions (rated 0-10). Read More

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Anxiety, depression, and function in individuals with chronic physical conditions: A longitudinal analysis.

Rehabil Psychol 2018 Nov 8;63(4):532-541. Epub 2018 Oct 8.

Department of Rehabilitation Medicine.

Objective: This longitudinal study examined the unique relationship between anxiety, symptoms (pain intensity, sleep disturbance, fatigue severity), and function domains (self-reported cognitive function, physical function, satisfaction with social roles) in individuals with chronic physical conditions, independent of depressive symptoms.

Method: Three surveys were mailed on an approximately yearly basis to community-dwelling adults with one of four chronic physical conditions (spinal cord injury, multiple sclerosis, muscular dystrophy, postpoliomyelitis syndrome). The first survey was completed by 1594 individuals (T1). Read More

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November 2018

Bone Mineral Density Among Individuals With Residual Lower Limb Weakness After Polio.

PM R 2019 05 25;11(5):470-475. Epub 2019 Mar 25.

Spaulding Outpatient Center Framingham, MA.

Background: Literature indicates that individuals with long-term residual lower extremity (LE) weakness after polio have decreased bone mineral density (BMD) related to muscle weakness. Where weakness is asymmetrical, bone densitometry measured only on the stronger LE may misclassify BMD.

Objective: To determine (1) whether femoral neck BMD differed from side to side in individuals with asymmetrical LE muscle weakness, and (2) the proportion of individuals at risk for underdiagnosis of low bone density or osteoporosis given unilateral assessment of the femoral neck. Read More

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[Polio and post-polio syndrome, viewed by patients and health professionals in primary care].

Rev Esp Salud Publica 2018 Jun 25;92. Epub 2018 Jun 25.

ICentro de Salud El Palo. Málaga. España.

Objective: Polio affects the quality of life of those who have suffered from it and causes health problems including the post-polio syndrome. The main goals of this work were to know the patients perspective of how they have been affected by the disease and establish the knowledge of post-polio syndrome among patients and primary health care professionals.

Methods: Interpretive qualitative research based on the Grounded Theory carried out in two health-care centers in the city of Malaga, one of them with care-rural clinics. Read More

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