892 results match your criteria Postpolio Syndrome


Post-Polio Syndrome Causing Late Onset Respiratory Failure.

Isr Med Assoc J 2020 Jun;22(6):395-396

Department of Internal Medicine C, Shamir Medical Center, Zerifin, Israel.

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Corticomotor Excitability in Two Kinds of Motor Neuron Diseases: A Study on the Patients With Amyotrophic Lateral Sclerosis and Poliomyelitis Survivors.

J Clin Neurophysiol 2020 May 26. Epub 2020 May 26.

Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Purpose: To examine upper motor neuron functions comparatively in patients with amyotrophic lateral sclerosis (ALS) and poliomyelitis survivors using transcranial magnetic stimulation (TMS) methods.

Methods: Single- and paired-pulse TMS with conventional methods and the triple-stimulation technique were performed by recording from the abductor digiti minimi and abductor pollicis brevis muscles in 31 patients with ALS, 18 patients with poliomyelitis survivors, and 21 controls. Nine patients were diagnosed as having postpoliomyelitis syndrome after a 6-month follow-up. Read More

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http://dx.doi.org/10.1097/WNP.0000000000000707DOI Listing

Psychometric properties of the Walking Impact Scale (Walk-12) in persons with late effects of polio.

PM R 2020 May 15. Epub 2020 May 15.

Department of Health Sciences, Lund University, Lund, Sweden.

Background: Many persons with late effects of polio (LEoP) perceive walking limitations in everyday life. A common rating scale to assess walking limitations is the Walking Impact Scale (Walk-12). However, there is limited knowledge about its psychometric properties. Read More

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http://dx.doi.org/10.1002/pmrj.12403DOI Listing

Longitudinal associations between physical activity, anxiety, and depression in adults with long-term physical disabilities.

Health Psychol 2020 Jun 23;39(6):529-538. Epub 2020 Mar 23.

Department of Rehabilitation Medicine.

Objective: To evaluate the longitudinal associations between self-reported physical activity and anxiety and depression symptom severity in adults with long-term physical disabilities.

Method: A secondary analysis of data from a United States-based longitudinal survey study of community-dwelling adults with 1 of 4 potential long-term physical disabilities (multiple sclerosis, muscular dystrophy, spinal cord injury, postpoliomyelitis syndrome). The first time point (T1) for the current study was completed by 1,594 participants. Read More

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http://dx.doi.org/10.1037/hea0000848DOI Listing

A twelve-week, four-arm, randomized, double-blind, placebo-controlled, phase 2 prospective clinical trial to evaluate the efficacy and safety of an anthroposophic multimodal treatment on chronic pain in outpatients with postpolio syndrome.

Brain Behav 2020 Apr 11;10(4):e01590. Epub 2020 Mar 11.

Department of Neurology, Universidade Federal de Sao Paulo, São Paulo, Brazil.

Introduction: Chronic pain and fatigue are the main symptoms of postpoliomyelitis syndrome (PPS). This study aimed to evaluate the efficacy and safety of an anthroposophic multimodal treatment for chronic pain in PPS outpatients.

Methods: A twelve-week, four-arm, randomized, double-blind, placebo-controlled, phase 2 prospective clinical trial was designed to compare four groups (n = 48): groups A and B received daily active experimental transdermal gel (ETG) or placebo gel (PTG), respectively; groups C and D received weekly external therapies, art therapies, and neurofunctional reorganization, plus either daily ETG or PTG, respectively. Read More

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http://dx.doi.org/10.1002/brb3.1590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177555PMC

A very long-term longitudinal follow-up of persons with late effects of polio.

Eur J Phys Rehabil Med 2020 Apr 10;56(2):155-159. Epub 2020 Feb 10.

Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.

Background: As many as 60-80% of persons with a history of polio myelitis develop new symptoms, such as new or increased muscle weakness, muscle and joint pain, and fatigue several decades later, called postpolio syndrome (PPS). This may affect their ability to perform activities of daily living (ADL). It is still unclear if the patient's symptom is getting worse and in that case how much/fast the decline is. Read More

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http://dx.doi.org/10.23736/S1973-9087.20.05918-3DOI Listing

Kaposi sarcoma in a patient with postpolio syndrome.

Cutis 2019 Nov;104(5):E20-E22

Departments of Radiation Oncology and Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA.

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November 2019

Goal Pursuit, Goal Adjustment, and Pain in Middle-Aged Adults Aging With Physical Disability.

J Aging Health 2019 12;31(10_suppl):214S-240S

University of Washington School of Medicine, Seattle, USA.

Aging with physical disability disrupts one's ability to achieve valued goals due to changes in symptoms and function. It is unclear how to cope optimally in this context. This study examined whether two possible strategies-tenacious goal pursuit (TGP) and flexible goal adjustment (FGA)-were associated with reduced pain interference and depressive symptoms and greater well-being, and protected against pain intensity, and FGA was more protective with increasing age and worse physical function. Read More

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http://dx.doi.org/10.1177/0898264319827142DOI Listing
December 2019

Polio and post-polio syndrome in non-Western immigrants: A new challenge for the healthcare system in Norway.

J Rehabil Med 2019 Dec;51(11):861-868

Department of Research, Sunnaas Rehabilitation Hospital, Bjørnemyrveien 11, NO-1450 Nesoddtangen, Norway.

Objective: To explore the health situation and identify specific health challenges in non-Western immigrants with polio in Norway, by comparing their status with Western immigrants with polio and native Norwegians with polio.

Design: A questionnaire covering demographics, polio history, life satisfaction, medical, psychological and social conditions was answered by 1,408 persons with polio, among them 34 immigrants from non-Western countries and 32 immigrants from Western countries.

Results: The non-Western immigrant polio group had a mean age of 46 years, were highly educated, reported high frequency of mental health problems and only one-third was working. Read More

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http://dx.doi.org/10.2340/16501977-2624DOI Listing
December 2019
1 Read

Resilience and Function in Adults With Chronic Physical Disabilities: A Cross-Lagged Panel Design.

Ann Behav Med 2020 Apr;54(5):297-307

Department of Rehabilitation Medicine, University of Washington, WA, USA.

Background: Resilience is a psychological construct referring to one's positive adaptation in response to adversity. Evidence suggests that resilience may contribute to various function domains in adults with chronic physical disabilities.

Purpose: To test hypothesized temporal associations between resilience and four function domains (anxiety, depression, social role satisfaction, and physical function) in individuals with chronic physical disabilities. Read More

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http://dx.doi.org/10.1093/abm/kaz048DOI Listing

Postpolio Syndrome: A Review of Lived Experiences of Patients.

Int J Appl Basic Med Res 2019 Jul-Sep;9(3):129-134

Department of Anatomical Sciences, University of Medicine and Health Sciences, Basseterre, St. Kitts and Nevis.

Postpolio syndrome (PPS) refers to a group of conditions that are present in patients, years after recovery from initial acute paralytic poliomyelitis. About 15%-80% of 20 million polio survivors worldwide will experience exacerbation of symptoms which typically appear 15-30 years after the resolution of initial poliomyelitis. Symptoms include new muscle weakness, fatigue, myalgia, joint pain, dysphagia, and difficulty breathing. Read More

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http://dx.doi.org/10.4103/ijabmr.IJABMR_333_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652271PMC
August 2019
15 Reads

Post-polio Syndrome: More Than Just a Lower Motor Neuron Disease.

Front Neurol 2019 16;10:773. Epub 2019 Jul 16.

Computational Neuroimaging Group, Academic Unit of Neurology, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

Post-polio syndrome (PPS) is a neurological condition that affects polio survivors decades after their initial infection. Despite its high prevalence, the etiology of PPS remains elusive, mechanisms of progression are poorly understood, and the condition is notoriously under-researched. While motor dysfunction is a hallmark feature of the condition, generalized fatigue, sleep disturbance, decreased endurance, neuropsychological deficits, sensory symptoms, and chronic pain are also often reported and have considerable quality of life implications in PPS. Read More

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https://www.frontiersin.org/article/10.3389/fneur.2019.00773
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http://dx.doi.org/10.3389/fneur.2019.00773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646725PMC
July 2019
4 Reads

Experiences of Speaking With Noninvasive Positive Pressure Ventilation: A Qualitative Investigation.

Am J Speech Lang Pathol 2019 07 15;28(2S):784-792. Epub 2019 Jul 15.

Department of Rehabilitation Medicine, University of Washington, Seattle.

Purpose The aim of this study was to describe experiences of speaking with 2 forms of noninvasive positive pressure ventilation (NPPV)-mouthpiece NPPV (M-NPPV) and nasal bilevel positive airway pressure (BPAP)-in people with neuromuscular disorders who depend on NPPV for survival. Method Twelve participants (ages 22-68 years; 10 men, 2 women) with neuromuscular disorders (9 Duchenne muscular dystrophy, 1 Becker muscular dystrophy, 1 postpolio syndrome, and 1 spinal cord injury) took part in semistructured interviews about their speech. All subjects used M-NPPV during the day, and all but 1 used BPAP at night for their ventilation needs. Read More

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http://dx.doi.org/10.1044/2019_AJSLP-MSC18-18-0101DOI Listing
July 2019
5 Reads

Secondary health conditions and social role satisfaction in adults with long-term physical disability.

Health Psychol 2019 May;38(5):445-454

Department of Rehabilitation Medicine, University of Washington.

Objective: Individuals living with physical disability due to early acquired or traumatic conditions often experience a range of psychological and physical health problems that are associated with their condition but are not directly caused by it. Known as "secondary health conditions," these problems can interact with existing functional limitations and other medical comorbidities to limit social participation. The current study assessed the concurrent and longitudinal associations between secondary health conditions, chronic medical comorbidities, and functional limitations, with a PROMIS® measure of social role participation. Read More

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http://dx.doi.org/10.1037/hea0000671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501832PMC
May 2019
9 Reads

Motor Unit Number Index (MUNIX) as a biomarker of motor unit loss in post-polio syndrome versus needle EMG.

J Electromyogr Kinesiol 2019 Jun 9;46:35-40. Epub 2019 Mar 9.

Department of Neurology, Medical University of Warsaw, 02-097 Warsaw, Banacha 1A str., Poland.

MUNIX method (Motor Unit Number Index) had been not used to assess number of motor neurons in post-polio syndrome in contrary to needle electromyography.

Objectives: To confirm if MUNIX reflects motor unit loss and clinical stage and to assess difference in MUNIX and EMG results between muscles in different stage.

Methods: 132 Muscles (MUNIX) and 96 (EMG) in 12 patients were studied and divided into groups: with normal strength(N), stable weakness and atrophy(S), new weakness and atrophy(W). Read More

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http://dx.doi.org/10.1016/j.jelekin.2019.03.006DOI Listing
June 2019
11 Reads

Neurological Symptoms in Danes with a History of Poliomyelitis: Lifelong Follow-Up of Late Symptoms, their Association with Initial Symptoms of Polio, and Presence of Postpolio Syndrome.

Eur Neurol 2018 5;80(5-6):295-303. Epub 2019 Mar 5.

Danish Center for Sleep Medicine, Department of Clinical Neurophysiology, Rigshospitalet, University of Copenhagen, Glostrup, Denmark.

Background: Previous studies suggest that patients with a history of poliomyelitis (PM) later in life experience a variety of symptoms. These studies were carried out in patients who later in life were admitted to hospital or became members of polio societies and may therefore not be representative of all polio patients. Little data have been published concerning patients actually discharged from hospital with a diagnosis of acute paralytic PM. Read More

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http://dx.doi.org/10.1159/000497483DOI Listing
June 2019
13 Reads

Efficacy of Oral Care Provided by Interprofessional Collaboration for a Patient with Esophageal Cancer Associated with Post-polio Syndrome during Neoadjuvant Chemotherapy.

Acta Med Okayama 2019 Feb;73(1):71-76

Dental Hygienist Team, Division of Medical Technology, Okayama University Hospital, Okayama 700-8558, Japan.

Preoperative oral care is helpful to prevent postoperative complications in patients who are undergoing esophagectomy. Here, we report the case of an 81-year-old Japanese man with an upper limb disability caused by post-polio syndrome who was receiving neoadjuvant chemotherapy for esophageal cancer. He had poor oral health status and developed oral complications as a side effect of chemotherapy. Read More

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http://ousar.lib.okayama-u.ac.jp/56461
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http://dx.doi.org/10.18926/AMO/56461DOI Listing
February 2019
8 Reads

Amyotrophic Lateral Sclerosis and its Mimics/Variants: A Comprehensive Review.

J Clin Imaging Sci 2018 6;8:53. Epub 2018 Dec 6.

Department of Radiology, Advocate Illinois Masonic Medical Center, Chicago, Illinois, USA.

Motor neuron diseases (MNDs) are a debilitating subset of diseases, which result in progressive neuronal destruction and eventual loss of voluntary muscular function. These entities are often challenging to distinguish and accurately diagnose given overlapping clinical pictures and overall rarity. This group of diseases has a high morbidity and mortality rate overall and delineating each type of disease can help guide appropriate clinical management and improve quality of life for patients. Read More

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http://dx.doi.org/10.4103/jcis.JCIS_40_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302559PMC
December 2018
36 Reads

Radiographic and Clinical Outcomes of Surgical Correction of Poliomyelitis-Related Spinal Deformities: A Comparison Among Three Types of Pelvic Instrumentations.

World Neurosurg 2019 Feb 12;122:e1111-e1119. Epub 2018 Nov 12.

Department of Spine Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China. Electronic address:

Background: We compared the clinical and radiographic outcomes of corrective surgery in patients with poliomyelitis-related spinal deformity (PSD) using 3 types of pelvic fixation and investigated the incidence and risk factors for complications.

Methods: We reviewed the data from 42 patients with PSD who had undergone spinopelvic reconstruction at a single institution from 2000 to 2016. Of the 42 patients, 15 had been treated with the Galveston technique, 13 with iliac screw fixation, and 14 with S2-alar-iliac (S2AI) screw fixation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183254
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http://dx.doi.org/10.1016/j.wneu.2018.10.238DOI Listing
February 2019
9 Reads
2.417 Impact Factor

Psychometric Properties of Three Fatigue Rating Scales in Individuals With Late Effects of Polio.

Ann Rehabil Med 2018 Oct 31;42(5):702-712. Epub 2018 Oct 31.

Department of Health Sciences, Lund University, Lund, Sweden.

Objective: To evaluate the psychometric properties of the Fatigue Severity Scale (FSS), the Fatigue Impact Scale (FIS), and the Multidimensional Fatigue Inventory (MFI-20) in persons with late effects of polio (LEoP). More specifically, we explored the data completeness, scaling assumptions, targeting, reliability, and convergent validity.

Methods: A postal survey including FSS, FIS, and MFI-20 was administered to 77 persons with LEoP. Read More

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http://e-arm.org/journal/view.php?doi=10.5535/arm.2018.42.5.
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http://dx.doi.org/10.5535/arm.2018.42.5.702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246856PMC
October 2018
21 Reads

Sex/gender disparities in health outcomes of individuals with long-term disabling conditions.

Rehabil Psychol 2019 May 8;64(2):221-228. Epub 2018 Oct 8.

Department of Rehabilitation Medicine.

Background: Women with disabling conditions experience health disparities relative to nondisabled women, but few studies have compared women and men with disabling conditions.

Objectives: To investigate gender differences in physical functioning and emotional health among individuals with long-term disabling conditions, that is, neuromuscular disease, multiple sclerosis, postpolio syndrome, or spinal cord injury.

Method: From a mailed survey of 1,862 adults with long-term disabling conditions, we used the 12-item Patient-Reported Outcomes Measurement Information System (PROMIS) physical functioning to assess physical limitations in activities and Patient Health Questionnaire-9 (PHQ-9) for emotional health and severity of secondary conditions (rated 0-10). Read More

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http://doi.apa.org/getdoi.cfm?doi=10.1037/rep0000248
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http://dx.doi.org/10.1037/rep0000248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453755PMC
May 2019
22 Reads

Anxiety, depression, and function in individuals with chronic physical conditions: A longitudinal analysis.

Rehabil Psychol 2018 Nov 8;63(4):532-541. Epub 2018 Oct 8.

Department of Rehabilitation Medicine.

Objective: This longitudinal study examined the unique relationship between anxiety, symptoms (pain intensity, sleep disturbance, fatigue severity), and function domains (self-reported cognitive function, physical function, satisfaction with social roles) in individuals with chronic physical conditions, independent of depressive symptoms.

Method: Three surveys were mailed on an approximately yearly basis to community-dwelling adults with one of four chronic physical conditions (spinal cord injury, multiple sclerosis, muscular dystrophy, postpoliomyelitis syndrome). The first survey was completed by 1594 individuals (T1). Read More

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http://doi.apa.org/getdoi.cfm?doi=10.1037/rep0000231
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http://dx.doi.org/10.1037/rep0000231DOI Listing
November 2018
13 Reads

Bone Mineral Density Among Individuals With Residual Lower Limb Weakness After Polio.

PM R 2019 05 25;11(5):470-475. Epub 2019 Mar 25.

Spaulding Outpatient Center Framingham, MA.

Background: Literature indicates that individuals with long-term residual lower extremity (LE) weakness after polio have decreased bone mineral density (BMD) related to muscle weakness. Where weakness is asymmetrical, bone densitometry measured only on the stronger LE may misclassify BMD.

Objective: To determine (1) whether femoral neck BMD differed from side to side in individuals with asymmetrical LE muscle weakness, and (2) the proportion of individuals at risk for underdiagnosis of low bone density or osteoporosis given unilateral assessment of the femoral neck. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19341482183086
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http://dx.doi.org/10.1016/j.pmrj.2018.08.387DOI Listing
May 2019
16 Reads

[Polio and post-polio syndrome, viewed by patients and health professionals in primary care].

Rev Esp Salud Publica 2018 Jun 25;92. Epub 2018 Jun 25.

ICentro de Salud El Palo. Málaga. España.

Objective: Polio affects the quality of life of those who have suffered from it and causes health problems including the post-polio syndrome. The main goals of this work were to know the patients perspective of how they have been affected by the disease and establish the knowledge of post-polio syndrome among patients and primary health care professionals.

Methods: Interpretive qualitative research based on the Grounded Theory carried out in two health-care centers in the city of Malaga, one of them with care-rural clinics. Read More

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June 2018
13 Reads

Post-polio syndrome and the late effects of poliomyelitis: Part 2. treatment, management, and prognosis.

Muscle Nerve 2018 12 23;58(6):760-769. Epub 2018 Aug 23.

Sunnybrook Health Sciences Centre, Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada.

Post-polio syndrome (PPS) is characterized by new muscle weakness and/or muscle fatigability that occurs many years after the initial poliomyelitis illness. An individualized approach to rehabilitation management is critical. Interventions may include rehabilitation management strategies, adaptive equipment, orthotic equipment, gait/mobility aids, and a variety of therapeutic exercises. Read More

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http://dx.doi.org/10.1002/mus.26167DOI Listing
December 2018
8 Reads

Postpolio syndrome and the late effects of poliomyelitis. Part 1. pathogenesis, biomechanical considerations, diagnosis, and investigations.

Muscle Nerve 2018 12 22;58(6):751-759. Epub 2018 Aug 22.

Sunnybrook Health Sciences Centre, Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, Canada.

Postpolio syndrome (PPS) is characterized by new muscle weakness and/or muscle fatigability that occurs many years after the initial poliomyelitis illness. Many theories exist regarding the pathogenesis of PPS, which remains incompletely understood. In contrast, the late effects of poliomyelitis are often a consequence of biomechanical alterations that occur as a result of polio-related surgeries, musculoskeletal deformities, or weakness. Read More

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http://dx.doi.org/10.1002/mus.26168DOI Listing
December 2018
9 Reads

Problems in Comparing Jitter Values Obtained with Voluntary Activation and Electrical Stimulation.

J Neuromuscul Dis 2018 ;5(2):225-230

Department of Neurology, Duke University Medical Center, Durham, NC, USA.

Comparing results from jitter studies performed with voluntary and electrical activation is difficult to perform quantitatively, particularly in complex signals as seen in reinnervation. High jitter values in individual spikes in these multispike signals can be missed with both activation methods, which introduces a bias towards more normal values.With voluntary activation, triggering on a spike from an abnormal end-plate in multispike potentials will overestimate individual jitter values and the number of abnormal jitter values. Read More

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http://dx.doi.org/10.3233/JND-170289DOI Listing
November 2018
10 Reads

Whole body vibration on people with sequelae of polio.

Physiother Theory Pract 2019 Jun 29;35(6):554-564. Epub 2018 Mar 29.

b Physical Therapy Department , TIRR - Memorial Hermann Rehabilitation and Research , Houston , TX , USA.

Purpose: The purpose was to explore the feasibility of whole body vibration (WBV) on polio survivors with/without post-polio syndrome (PPS) by studying its effects on walking speed (10-m walk test), endurance (2-min walk test), pain severity/interference (Brief Pain Inventory [BPI]), sleep quality (Pittsburg Sleep Quality Index), fatigue (Fatigue Severity Scale), leg strength (manual muscle testing and hand-held dynamometry), and muscle cramping (written logs).

Methods: Fifteen individuals completed the study, participating in eight sessions in two 4-week blocks. Participants started with ten 1-min vibration bouts/session, increasing to 20 min. Read More

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http://dx.doi.org/10.1080/09593985.2018.1454559DOI Listing
June 2019
6 Reads

Ultrasound-Guided Carpal Tunnel Release Using Dynamic Expansion of the Transverse Safe Zone in a Patient With Postpolio Syndrome: A Case Report.

PM R 2018 10 6;10(10):1115-1118. Epub 2018 Mar 6.

Department of Neurosurgery, University of Michigan, Ann Arbor, MI.

The prevalence of carpal tunnel syndrome (CTS) in patients with postpolio syndrome occurs at a rate of 22%. Irrespective of those with CTS, 74% of postpolio patients weight bear through their arms for ambulation or transfers. As open carpal tunnel release is performed along the weight-bearing region of the wrist, their functional independence may be altered while recovering. Read More

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http://dx.doi.org/10.1016/j.pmrj.2018.02.016DOI Listing
October 2018
12 Reads

[Beneficial Effect of Medical Cannabis in the Treatment of a Pharmacoresistant Nausea Associated with a Somatoform Disorder in a Patient with Post-Polio Syndrome].

Dtsch Med Wochenschr 2018 Mar 5;143(5):344-348. Epub 2018 Mar 5.

Institut für Hausarztmedizin der Medizinischen Fakultät der Universität Bonn.

History And Clinical Findings:  We report a 79-year-old patient with post-polio syndrome (PPS). In the course of this disease, recurrent upper abdominal pain and a therapy-resistant nausea developed without vomiting. In addition, the patient was limited by the combination of muscular weakness, obesity, dietary-treated diabetes and a degenerative spinal cord injury significantly in its mobility and physical capacity. Read More

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http://dx.doi.org/10.1055/s-0043-123897DOI Listing
March 2018
21 Reads

Sense of Coherence in persons with late effects of polio.

NeuroRehabilitation 2018 ;42(1):103-111

Department of Health Sciences, Rehabilitation Medicine Research Group, Lund University, Sweden.

Background: Sense of Coherence (SOC) is important for successful adaptation and mental well-being in people with life-long medical conditions. Late effects of polio (LEoP) often lead to a life-long disability, but no study has assessed SOC in this population.

Objective: To assess SOC in persons with LEoP and to explore the association between SOC, demographics (age, gender, marital status and level of education) and variables related to LEoP (age at polio onset, number of years from polio until onset of LEoP and self-rated disability). Read More

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http://dx.doi.org/10.3233/NRE-172198DOI Listing
July 2018
13 Reads

Repetitive transcranial magnetic stimulation in treatment of post polio syndrome.

Neurol Neurochir Pol 2018 Mar 5;52(2):281-284. Epub 2017 Nov 5.

Department of Neurosurgery, Warsaw University of Medicine, Cegłowska 80, 01-809 Warsaw, Poland.

Background: Post polio syndrome is a rare disease that occurs decades after polio virus infection. Repetitive transcranial magnetic stimulation (rTMS) is a treatment option with proved effectiveness in drug resistant depression. Possibly it can be helpful in therapy of other neurological diseases including post polio syndrome. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00283843173031
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http://dx.doi.org/10.1016/j.pjnns.2017.10.013DOI Listing
March 2018
15 Reads

Restless legs syndrome is highly prevalent in patients with postpolio syndrome.

Sleep Med 2018 01 22;41:112. Epub 2017 Oct 22.

Neurology, Department of Systems Medicine, Tor Vergata University and Hospital, Rome, Italy.

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http://dx.doi.org/10.1016/j.sleep.2017.09.020DOI Listing
January 2018
13 Reads

Polio survivors perceptions of a multi-disciplinary rehabilitation programme.

Disabil Rehabil 2019 01 3;41(2):150-157. Epub 2017 Oct 3.

a School of Health and Social Care , London Southbank University , London , UK.

Purpose: Post-polio syndrome refers to a late complication of the poliovirus infection. Management of post-polio syndrome is complex due to the extensive symptomology. European and United Kingdom guidelines have advised the use of rehabilitation programmes to manage post-polio syndrome. Read More

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http://dx.doi.org/10.1080/09638288.2017.1381184DOI Listing
January 2019
7 Reads

Restless legs syndrome is highly prevalent in patients with post-polio syndrome.

Sleep Med 2017 Sep 22;37:147-150. Epub 2017 Jul 22.

Neuro-Sono, Department of Neurology, Universidade de São Paulo, São Paulo, Brazil.

Objective: Few studies have quantified the prevalence of restless legs syndrome (RLS) in patients with post-polio syndrome (PPS). Our objective was to assess the prevalence and severity of RLS in patients with PPS and to examine the demographic characteristics of this population.

Method: This was a cross-sectional study conducted from April 2010 to May 2012 at the outpatient Neuromuscular Disorders clinic of Universidade Federal de São Paulo, São Paulo, Brazil. Read More

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http://dx.doi.org/10.1016/j.sleep.2017.06.025DOI Listing
September 2017
10 Reads

Systematic review of the evidence on orthotic devices for the management of knee instability related to neuromuscular and central nervous system disorders.

BMJ Open 2017 Sep 5;7(9):e015927. Epub 2017 Sep 5.

Kingston University, Kingston-Upon-Thames, London, UK.

Objectives: To assess the effectiveness of orthotic devices for the management of instability of the knee in adults with a neuromuscular disorder or central nervous system disorder.

Design: A systematic review of primary studies.

Setting: Community. Read More

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http://dx.doi.org/10.1136/bmjopen-2017-015927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588970PMC
September 2017
39 Reads

Perceived consequences of ageing with late effects of polio and strategies for managing daily life: a qualitative study.

BMC Geriatr 2017 08 9;17(1):179. Epub 2017 Aug 9.

Department of Health Sciences, Lund University, Box 157, SE-221 00, Lund, Sweden.

Background: New or increased impairments may develop several decades after an acute poliomyelitis infection. These new symptoms, commonly referred to as late effects of polio (LEoP), are characterised by muscular weakness and fatigue, generalised fatigue, pain at rest or during activities and cold intolerance. Growing older with LEoP may lead to increased activity limitations and participation restrictions, but there is limited knowledge of how these persons perceive the practical and psychological consequences of ageing with LEoP and what strategies they use in daily life. Read More

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http://dx.doi.org/10.1186/s12877-017-0563-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551026PMC
August 2017
10 Reads

Gait patterns in association with underlying impairments in polio survivors with calf muscle weakness.

Gait Posture 2017 10 23;58:146-153. Epub 2017 Jul 23.

Department of Rehabilitation, Academic Medical Center, University of Amsterdam, The Netherlands.

The objective was to identify gait patterns in polio survivors with calf muscle weakness and associate them to underlying lower extremity impairments, which are expected to help in the search for an optimal orthosis. Unilaterally affected patients underwent barefoot 3D-gait analyses. Gait pattern clusters were created based on the ankle and knee angle and ankle moment shown in midstance of the affected limb. Read More

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http://dx.doi.org/10.1016/j.gaitpost.2017.07.107DOI Listing
October 2017
35 Reads

Comparison of activity and fatigue of the respiratory muscles and pulmonary characteristics between post-polio patients and controls: A pilot study.

PLoS One 2017 27;12(7):e0182036. Epub 2017 Jul 27.

Physical Medicine and Rehabilitation department, Hadassah Mount Scopus, Jerusalem, Israel.

Objectives: To compare pulmonary function measures, maximal respiratory pressure and fatigue of respiratory muscles between patients with Post-Polio Syndrome (PPS) and controls.

Design: Cross-sectional study.

Patients: Patients with PPS (N = 12; age 62. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182036PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531432PMC
September 2017
47 Reads

Revealing enterovirus infection in chronic human disorders: An integrated diagnostic approach.

Sci Rep 2017 07 10;7(1):5013. Epub 2017 Jul 10.

Medical Microbiology, Dept. of Biotechnology and Life Sciences, University of Insubria, Varese, 21100, Italy.

Enteroviruses (EVs) causing persisting infection are characterized by minimal replication and genetic changes. Typing of these agents may complement disease assessment and shed light on pathogenesis. Here we report an integrated approach for EV detection in human samples that is based on pre-enrichment of virus in cell culture before search for the viral genome and viral antigens. Read More

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http://dx.doi.org/10.1038/s41598-017-04993-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504018PMC
July 2017
25 Reads

Measuring Physical and Cognitive Fatigue in People With Post-Polio Syndrome: Development of the Neurological Fatigue Index for Post-Polio Syndrome (NFI-PP).

PM R 2018 02 27;10(2):129-136. Epub 2017 Jun 27.

Walton Centre NHS Trust, Lower Lane, Liverpool, L9 7LJ, United Kingdom.

Background: Fatigue in post-polio syndrome (PPS) has been shown to affect quality of life adversely. There is currently no disease-specific measure of fatigue for PPS.

Objective: To develop a scale to measure fatigue in PPS that meets rigorous psychometric standards. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19341482163111
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http://dx.doi.org/10.1016/j.pmrj.2017.06.014DOI Listing
February 2018
24 Reads

Cognitive behavioural therapy for reducing fatigue in post-polio syndrome and in facioscapulohumeral dystrophy: A comparison.

J Rehabil Med 2017 Jul;49(7):585-590

Department of Rehabilitation, Academic Medical Center, University of Amsterdam, PO 22660, 1100 DD Amsterdam, The Netherlands.

Background: Cognitive behavioural therapy does not reduce fatigue in post-polio syndrome, but is effective in facioscapulohumeral dystrophy. This difference in efficacy might be explained by a different role of cognitions in these conditions.

Objective: To compare fatigue-related cognitions between patients with post-polio syndrome and facio-scapulohumeral dystrophy. Read More

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http://dx.doi.org/10.2340/16501977-2247DOI Listing
July 2017
25 Reads

Post-Polio-Like Syndrome.

Am J Med 2017 11 10;130(11):e491-e492. Epub 2017 Jun 10.

Department of General Medicine, Chiba University Hospital, Japan.

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http://dx.doi.org/10.1016/j.amjmed.2017.05.024DOI Listing
November 2017
38 Reads

Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews.

Cochrane Database Syst Rev 2017 04 24;4:CD011279. Epub 2017 Apr 24.

Division of Population Health Sciences, University of Dundee, Dundee, UK.

Background: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%. Read More

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http://dx.doi.org/10.1002/14651858.CD011279.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461882PMC
April 2017
49 Reads

Accounting for polio survivors in the post-polio world.

Authors:
Sophie Cousins

Lancet 2017 04;389(10078):1503-1504

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http://dx.doi.org/10.1016/S0140-6736(17)30999-6DOI Listing
April 2017
11 Reads

Relationship of depression and medications on incidence of falls among people with late effects of polio.

Physiother Theory Pract 2017 May 11;33(5):370-375. Epub 2017 Apr 11.

d Department of Clinical Psychology , Alliant International University , San Francisco , CA , USA.

The purpose of this study was to determine if falls in polio survivors, with or without post-polio syndrome (PPS), are related to number of medications taken, use of anti-depressant or psychoactive medications, or self-report of depression. A survey was sent to 300 members of a regional polio support group, asking them to document their fall history, medications used, and the presence of depression. Depression was measured by self-report and with the Geriatric Depression Scale, short form (GDS-15). Read More

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http://dx.doi.org/10.1080/09593985.2017.1307889DOI Listing
May 2017
9 Reads

Assessment of energy expenditure in individuals with post-poliomyelitis syndrome.

Arq Neuropsiquiatr 2017 Mar;75(3):147-152

Universidade Federal de São Paulo, Setor de Investigação nas Doenças Neuromusculares, São Paulo SP, Brasil.

Methods: The Baecke questionnaire for the evaluation of habitual physical activity (HPA), assessment of quality of life (WHOQOL-Bref), and the Fatigue Severity Scale were administered to patients with PPS, poliomyelitis sequelae (PS) and to a control group (CG). Participated in the study 116 individuals (PPS=52,PS= 28,CG=36).

Results: Patients with PPS tended to increase their HPA from 10 to 20 years of age, compared with those in the PS group and the CG. Read More

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http://dx.doi.org/10.1590/0004-282X20170013DOI Listing
March 2017
52 Reads

Treatment with L-citrulline in patients with post-polio syndrome: study protocol for a single-center, randomised, placebo-controlled, double-blind trial.

Trials 2017 03 9;18(1):116. Epub 2017 Mar 9.

Division of Neuropediatrics, University of Basel Children's Hospital, Spitalstrasse 33, Postfach 4031, Basel, Switzerland.

Background: Post-polio syndrome (PPS) is a condition that affects polio survivors years after recovery from an initial acute infection by the Poliomyelitis virus. Most often, patients who suffered from polio start to experience gradual new weakening in muscles, a gradual decrease in the size of muscles (muscle atrophy) and fatigue years after the acute illness. L-citrulline is known to change muscular metabolism synthesis by raising nitric oxide (NO) levels and increasing protein synthesis. Read More

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http://dx.doi.org/10.1186/s13063-017-1829-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343398PMC
March 2017
40 Reads

A patient with postpolio syndrome developed cauda equina syndrome after neuraxial anesthesia: A case report.

J Clin Anesth 2017 Feb 27;37:49-51. Epub 2016 Dec 27.

Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, ROC. Electronic address:

Combined spinal anesthesia and postoperative epidural analgesia is widely used in orthopedic surgery. Uncommon but serious neurologic complications of neuraxial anesthesia (NA) include direct trauma during needle or catheter insertion, central nervous system infections, and neurotoxicity of local anesthetics. Cauda equina syndrome (CES) is a rare complication after NA but can result in severe neurologic deterioration that may require surgical intervention. Read More

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http://dx.doi.org/10.1016/j.jclinane.2016.09.032DOI Listing
February 2017
15 Reads

Post-polio syndrome. Cases report and review of literature.

Neurol Neurochir Pol 2017 Mar - Apr;51(2):140-145. Epub 2017 Feb 3.

Department of Neurology, Specialized Regional Hospital, Ciechanów, Poland. Electronic address:

It is estimated that around 15 million people survived polio infection worldwide since early twentieth century. In 1950 effective vaccination was used for first time. Since that time number of affected people decreased. Read More

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http://dx.doi.org/10.1016/j.pjnns.2017.01.009DOI Listing
August 2017
115 Reads