929 results match your criteria Postpolio Syndrome

Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report.

J Dent Anesth Pain Med 2022 Jun 27;22(3):233-237. Epub 2022 May 27.

Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.

Postpolio syndrome (PPS) is widely known to manifest as muscle weakness in patients affected by poliomyelitis in early childhood. This is caused by the long-term overwork of motor nerves regenerated from surviving nerve cells. We report a characteristic delay in recovery from muscle relaxation after administering rocuronium to a patient with PPS under general anesthesia with desflurane. Read More

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Describing post-polio syndrome.

Neurologia (Engl Ed) 2022 Jun 5;37(5):346-354. Epub 2021 May 5.

Servicio de Rehabilitación, Institut Guttmann, Barcelona, Spain.

Introduction: Patients presenting sequelae of poliomyelitis may present new symptoms, known as post-polio syndrome (PPS).

Objective: To identify the clinical and functional profile and epidemiological characteristics of patients presenting PPS.

Patients And Methods: We performed a retrospective study of 400 patients with poliomyelitis attended at the Institut Guttmann outpatient clinic, of whom 310 were diagnosed with PPS. Read More

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Measurement properties of the Falls Efficacy Scale-International (FES-I) in persons with late effects of polio: a cross-sectional study.

PM R 2022 Jun 6. Epub 2022 Jun 6.

Department of Health Sciences, Lund University, Lund, Sweden.

Background: Fear of falling (FoF) is very common in persons with late effects of polio (LEoP). An internationally recognized rating scale to assess FoF is the Falls Efficacy Scale-International (FES-I). Yet, there is limited knowledge about its measurement properties in persons with LEoP. Read More

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Factors associated with walking adaptability and its association with falling in polio survivors.

Arch Phys Med Rehabil 2022 May 26. Epub 2022 May 26.

Amsterdam UMC, University of Amsterdam, Department of Rehabilitation Medicine, Amsterdam Movement Sciences, Meibergdreef 9, Amsterdam, the Netherlands. Electronic address:

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Outcomes Following Total Hip Arthroplasty in Patients With Postpolio Syndrome: A Matched Cohort Analysis.

J Arthroplasty 2022 Apr 18. Epub 2022 Apr 18.

Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT.

Background: Patients with postpolio syndrome (PPS) may be afflicted by hip arthritis in either the paralytic or contralateral limb. Total hip arthroplasty (THA) may be considered in these patients. However, short-term and long-term outcomes following THA in PPS patients remain poorly characterized. Read More

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Postpolio Syndrome from Non-Paralytic Poliovirus Infection.

Intern Med 2022 Mar 5. Epub 2022 Mar 5.

Department of Neurology, National Hospital Organization Higashi-Ohmi General Medical Center, Japan.

A 73-year-old man presented with muscle weakness and atrophy of his right arm. Atrophy of his left brachia and left calf had occurred 13 years before without any improvement or deterioration. His sister and cousin had a history of paralytic poliomyelitis. Read More

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Spinal cord gray matter atrophy is associated with functional decline in post-polio syndrome.

Eur J Neurol 2022 05 3;29(5):1435-1445. Epub 2022 Mar 3.

Neurology Clinic and Policlinic, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.

Objective: To determine if patients with post-polio syndrome (PPS) show spinal cord gray matter (SCGM) atrophy and to assess associations between SCGM atrophy, muscle strength and patient-reported functional decline.

Methods: Twenty patients diagnosed with PPS (March of Dimes criteria) and 20 age- and sex-matched healthy controls (HC) underwent 3T axial 2D-rAMIRA magnetic resonance imaging at the intervertebral disc levels C2/C3-C6/C7, T9/T10 and the lumbar enlargement level (T ) (0.5 × 0. Read More

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Sixty-nine years after surviving the polio epidemic.

CMAJ 2021 12;193(50):E1915-E1917

Patient (McMahon), Ottawa, Ont.; Ottawa Hospital Rehabilitation Centre (Dojeiji), Ottawa, Ont.; Bruyère Continuing Care (Leiva); Department of Family Medicine (Dojeiji, Leiva), University of Ottawa, Ottawa, Ont.; Friend (Fisher), Ottawa, Ont.

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December 2021

Treatment with L-Citrulline in patients with post-polio syndrome: A single center, randomized, double blind, placebo-controlled trial.

Neuromuscul Disord 2021 11 24;31(11):1136-1143. Epub 2021 Aug 24.

Division of Pediatric Neurology, University Children's Hospital Basel (UKBB), University of Basel, Switzerland.

This single-centered, randomized, double-blind, placebo-controlled study reports the results of L-Citrulline treatment for 24 weeks in patients with post-polio syndrome (PPS). Twenty-nine patients were randomized and assigned into receiving a treatment of 15 g L-Citrulline or placebo. The primary endpoint was the change of the 6 min walking distance test. Read More

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November 2021

Sense of coherence and coping behaviours in persons with late effects of polio.

Ann Phys Rehabil Med 2022 May 30;65(3):101577. Epub 2021 Nov 30.

Department of Health Sciences, Lund University, Lund, Sweden; Department of Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden.

Background: Sense of coherence (SOC), comprising "comprehensibility", "manageability" and "meaningfulness", is important for successful adaptation in persons with late effects of polio (LEoP) and can be used as an estimate of the ability to cope with stressors. Coping behaviours are the actions a person performs to reduce stress and can be divided into problem-focused coping, emotion-focused coping and less useful coping. Our knowledge is very limited of what coping behaviours persons with LEoP use to manage their life situation as well as the association between SOC and coping behaviours. Read More

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Spread of vimentin-immunoreactive cells within the plaque-like lesion in the spinal anterior horn of a patient with post-poliomyelitis syndrome.

Neuropathology 2021 Oct 19;41(5):406-411. Epub 2021 Sep 19.

Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan.

A Japanese man in the present study experienced acute weakness in his right leg as a two year old. The strength in his leg gradually recovered and developed, and he could play golf and climb mountains up to around the age of 50. From approximately 55 years of age, he became unable to stand up from a stooped position. Read More

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October 2021

[Post-polio Syndrome in the Perioperative Phase].

Anasthesiol Intensivmed Notfallmed Schmerzther 2021 Sep 10;56(9):628-634. Epub 2021 Sep 10.

Due to the numerous poliomyelitis epidemics that have continued over the last decades and the post-polio syndrome (PPS) that occurs 10 - 30 years after poliomyelitis infection, the prevalence of PPS is also expected to increase in Europe. At the same time, due to the musculoskeletal disorders associated with the underlying disease, PPS patients often require surgery for which special anaesthetic requirements must be taken into account. In this analysis we summarise the current evidence and recommendations. Read More

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September 2021

Knowledge of healthcare professionals about poliomyelitis and postpoliomyelitis: a cross-sectional study.

Sao Paulo Med J 2021 Aug-Sep;139(5):464-475

MD, PhD. Physician and Scientific Assistant, Institute of Primary Care, University of Zurich, Zurich, Switzerland; and Researcher, Medbase St. Gallen Am Vadianplatz, St. Gallen, Switzerland.

Background: Postpoliomyelitis syndrome is a clinical condition that can affect poliomyelitis survivors.

Objective: Our aim was to evaluate knowledge of poliomyelitis and postpoliomyelitis syndrome among Brazilian healthcare professionals.

Design And Setting: Cross-sectional study conducted at a Brazilian public higher education institution located in the state of Goiás. Read More

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October 2021

Fall-Related Activity Avoidance among Persons with Late Effects of Polio and Its Influence on Daily Life: A Mixed-Methods Study.

Int J Environ Res Public Health 2021 07 5;18(13). Epub 2021 Jul 5.

Department of Health Sciences, Lund University, 221 00 Lund, Sweden.

Falls are common among persons with late effects of polio (LEoP), which may lead to fear of falling and activity avoidance in everyday life. Here, we assessed the occurrence of fall-related activity avoidance among persons with LEoP and explored how these experiences influenced daily life. Fourteen ambulatory persons (seven women; mean age 70 years) with LEoP participated. Read More

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Pandemics Shaping our World.

Phys Med Rehabil Clin N Am 2021 08 3;32(3):xiii-xiv. Epub 2021 Jun 3.

Department of Physical Medicine & Rehabilitation, Spaulding Rehabilitation Hospital/Harvard Medical School, 300 First Avenue, Charlestown, MA 02129, USA. Electronic address:

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Phys Med Rehabil Clin N Am 2021 08;32(3):xi-xii

DiDepartment of Orthopaedics, Campbell Clinic Orthopaedics, University of Tennessee, Memphis, TN, USA; 1400 South Germantown Road, Germantown, TN 38138, USA. Electronic address:

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Medical Comorbidities and Complications Associated with Poliomyelitis and Its Sequelae.

Phys Med Rehabil Clin N Am 2021 08 20;32(3):591-600. Epub 2021 May 20.

Department of Physical Medicine and Rehabilitation, University of Miami Leonard M. Miller School of Medicine, PO Box 016960 (C-206), Miami, FL 33101, USA.

Survivors of poliomyelitis may experience long-term sequelae that put them at increased risk for injury, pain, cardiovascular deconditioning, and functional decline. Osteoporotic fractures and entrapment neuropathies, in particular, may result in greater impairments in one's mobility and ability to perform activities of daily living. Dysphagia may necessitate the use of compensatory swallow strategies to minimize aspiration risk. Read More

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Palliative Care for Polio and Postpolio Syndrome.

Phys Med Rehabil Clin N Am 2021 08 26;32(3):569-579. Epub 2021 May 26.

Wang Ambulatory Care Center, Suite 835, 15 Parkman Street, Boston, MA 02114, USA; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Division of Palliative Care, Massachusetts General Hospital, Boston, MA, USA. Electronic address:

Palliative care is a team-based approach focusing on relief of physical, psychosocial, and existential distress and communication about serious illness. Patients with poliomyelitis and postpolio syndrome are at risk for contractures and can benefit from involvement of physical and occupational therapy. Hypersialorrhea can be treated with anticholinergic medications, botox, or radiation. Read More

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Psychiatric Approaches and Outcomes.

Phys Med Rehabil Clin N Am 2021 08 26;32(3):557-568. Epub 2021 May 26.

Independent Practice, Belmont, MA, USA; Independent Practice, Framingham, MA, USA. Electronic address:

Since the 1940s, the importance of addressing polio survivors' psychological issues along with their physical needs has been known. The clinical literature and polio survivors' narratives indicate positive responses to both psychotherapy and psychologically informed medical care for issues connected with acute polio and rehabilitation experiences as well as post-polio syndrome. Yet, barriers in the form of stigma and lack of awareness and resources prevent most from accessing such care. Read More

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Joint and Back Pain: Medications and Role of Injection Therapy for Destructive Joint.

Phys Med Rehabil Clin N Am 2021 08 20;32(3):537-546. Epub 2021 May 20.

Icahn School of Medicine at Mount Sinai, 5 East 98th Street, Sixth Floor, Box 1240B, New York, New York 10029, USA.

Postpolio syndrome (PPS) is a sequela with symptoms that often occur in patients who previously survived poliomyelitis. Pain is a characteristic feature of PPS. Although poliomyelitis is no longer commonly seen in the western world, there is a significant portion of patients living with PPS. Read More

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Nerve Conduction Study/Electromyography: Common Neuropathies and Considerations for Patients with Polio.

Andrew Dubin

Phys Med Rehabil Clin N Am 2021 08 12;32(3):527-535. Epub 2021 May 12.

Division of PM&R, Department of Orthopedics and Rehabilitation Medicine, University of Florida, 3450 Hull Road Suite 3301, POB 112727, Gainesville, FL 32611, USA. Electronic address:

Acute poliomyelitis is now extremely rare in the United States. Worldwide there are still sporadic outbreaks, which are typically treated with acute inoculation programs. Although polio has effectively been eradicated, the full scope of the disease and its myriad manifestations both in the acute phase and in the postpolio syndrome phase, remain areas of fertile research, debate, and stimulating topics. Read More

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Bracing: Upper and Lower Limb Orthoses.

Phys Med Rehabil Clin N Am 2021 08 20;32(3):509-526. Epub 2021 May 20.

LPG Physiatry, 765 Allens Avenue, Suite 110, Providence, RI 02905, USA. Electronic address:

The goals of bracing in polio and postpolio are to optimize joint position and support weak muscles with the goal of reducing falls, reducing deformities, and optimizing energy conservation. Orthoses are primarily used in the lower extremities to optimize gait. Less frequently, upper extremity orthoses are required. Read More

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Approach to Fatigue and Energy Conservation.

Phys Med Rehabil Clin N Am 2021 08 20;32(3):493-507. Epub 2021 May 20.

Spaulding Outpatient Center Framingham, 570 Worcester Road, Framingham, MA 01702, USA.

Fatigue, a common complaint in individuals with postpolio syndrome (PPS), is defined as an overwhelming sustained feeling of exhaustion and diminished capacity for physical and mental work. A comprehensive medical work-up is needed to rule out all other causes of fatigue. A sleep study should be considered for individuals with PPS who complain of fatigue. Read More

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The Current State: Epidemiology and Working Toward Eradication.

Phys Med Rehabil Clin N Am 2021 08 29;32(3):467-476. Epub 2021 Apr 29.

Department of Physical Medicine and Rehabilitation, UC Davis Health, 4860 Y Street, Suite 3850, Sacramento, CA 95817, USA.

Acute polio, once epidemic and a significant source of paralysis and disability, has been dramatically reduced through global vaccination programs. Although vaccination efforts have experienced a setback because of COVID-19, resulting in increased number of vaccine-associated and wild virus infections, polio eradication is still a realistic goal that will result in significant cost savings. The secondary health issues related to aging with the residual effects of polio, including postpolio syndrome, will persist for many years posteradication. Read More

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Unilateral chilblains affecting the lower limb with post-polio residual paralysis: An example of immunocompromised cutaneous district.

Indian J Dermatol Venereol Leprol 2021 [SEASON];87(4):558-559

Department of Dermatology and Venereology All India Institute of Medical Sciences, New Delhi, India.

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January 2022

Effectiveness of Intravenous Immunoglobulin for Management of Pain in Patients with Postpolio Syndrome.

Pain Res Manag 2021 20;2021:6637705. Epub 2021 Mar 20.

Department of Physical Medicine and Rehabilitation, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.

Objective: Many patients with postpolio syndrome (PPS) experience pain. In this study, we aimed to review previous studies to investigate the effectiveness of intravenous immunoglobulin (IVIG) for managing pain in patients with PPS. We performed a narrative review. Read More

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Imaging as an alternate diagnostic modality in a presumptive case of abdominopelvic TB in a COVID-19 patient.

BMJ Case Rep 2021 Mar 2;14(3). Epub 2021 Mar 2.

Obstetrics and Gynaecology, Jawaharlal Institute of Postgraduate Medical Education, Puducherry, India.

A 30-year-old, multiparous widow, with postpolio residual paralysis, presented with complaints of dull aching abdominal pain for 15 days. Ultrasound showed a mixed echogenic right adnexal mass with free fluid in the pelvis and abdomen. CT abdomen and pelvis revealed partially defined peripherally enhancing collection in lower abdomen and right adnexa suggestive of tubo-ovarian abscess. Read More

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Extra-motor manifestations in post-polio syndrome (PPS): fatigue, cognitive symptoms and radiological features.

Neurol Sci 2021 Nov 26;42(11):4569-4581. Epub 2021 Feb 26.

Computational Neuroimaging Group, Trinity Biomedical Sciences Institute, Trinity College Dublin, Room 5.43, Pearse Street, Dublin 2, Ireland.

Background: There is a paucity of cerebral neuroimaging studies in post-polio syndrome (PPS), despite the severity of neurological and neuropsychological sequelae associated with the condition. Fatigue, poor concentration, limited exercise tolerance, paraesthesia and progressive weakness are frequently reported, but the radiological underpinnings of these symptoms are poorly characterised.

Objective: The aim of this study is to evaluate cortical and subcortical alterations in a cohort of adult polio survivors to explore the anatomical substrate of extra-motor manifestations. Read More

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November 2021

Prevalence and Effect of Obesity on Mobility According to Different Criteria in Polio Survivors.

Am J Phys Med Rehabil 2021 03;100(3):250-258

From the Department of Rehabilitation Medicine, Seongnam Citizens Medical Center, Seongnam-si (K-HS); Department of Rehabilitation Medicine, Dongmasan General Hospital, Masan-Si (JHL); Department of Physical Medicine and Rehabilitation, Soonchunhyang University Bucheon Hospital, Bucheon-si (S-YL); and Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-si, Korea (JYL, J-YL).

Objective: Obesity is a major and functionally important problem in polio survivors. The aim of this study was to investigate the prevalence of obesity using body mass index and percentage body fat in polio survivors and to analyze the relationship between obesity and mobility.

Design: Eighty-four polio survivors were included. Read More

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Postpoliomyelitis Syndrome and Reversal With Sugammadex: A Case Report.

AANA J 2020 Oct;88(5):380-382

is an adjunct associate professor of anesthesiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, and University of Cincinnati Medical Center.

Postpolio syndrome (PPS) is a disabling process characterized by progressive muscle weakness and atrophy that typically emerges decades after an initial poliomyelitis infection. Although the exact incidence of PPS is unknown, it is estimated that 25% to 40% of all poliomyelitis survivors are affected. Patients with PPS may have increased sensitivity to numerous anesthetic agents including neuromuscular blocking drugs. Read More

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October 2020