300 results match your criteria Postpolio Syndrome


Poliomyelitis.

Handb Clin Neurol 2018 ;159:337-344

Neuroscience Research Australia, Randwick, Sydney, NSW, Australia. Electronic address:

Poliomyelitis, often termed "polio," is an acute infectious disease caused by an enterovirus which damages the anterior horn cells of the spinal cord and brainstem. Progress to lower motor neurone cell death leads to disruption of motor units and subsequent muscle weakness or complete paralysis. Although the virus is mostly eradicated from the Western world, postpolio decline is prevalent among people aged 60 years and over. Read More

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January 2018
2 Reads

Sex/gender disparities in health outcomes of individuals with long-term disabling conditions.

Rehabil Psychol 2018 Oct 8. Epub 2018 Oct 8.

Department of Rehabilitation Medicine.

Background: Women with disabling conditions experience health disparities relative to nondisabled women, but few studies have compared women and men with disabling conditions.

Objectives: To investigate gender differences in physical functioning and emotional health among individuals with long-term disabling conditions, that is, neuromuscular disease, multiple sclerosis, postpolio syndrome, or spinal cord injury.

Method: From a mailed survey of 1,862 adults with long-term disabling conditions, we used the 12-item Patient-Reported Outcomes Measurement Information System (PROMIS) physical functioning to assess physical limitations in activities and Patient Health Questionnaire-9 (PHQ-9) for emotional health and severity of secondary conditions (rated 0-10). Read More

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October 2018
5 Reads

Bone Mineral Density Among Individuals With Residual Lower Limb Weakness After Polio.

PM R 2018 Sep 7. Epub 2018 Sep 7.

Spaulding Outpatient Center Framingham, MA.

Background: Literature indicates that individuals with long-term residual lower extremity (LE) weakness after polio have decreased bone mineral density (BMD) deficiencies related to muscle weakness. Where weakness is asymmetrical, bone densitometry (BDt) measured only on the stronger LE may misclassify BMD.

Objective: To determine (1) whether femoral neck BMD differed from side to side in individuals with asymmetrical LE muscle weakness, and (2) the proportion of individuals at risk for underdiagnosis of low bone density or osteoporosis given unilateral assessment of the femoral neck. Read More

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September 2018
10 Reads

Newcastle Disease Virus-Based Vectored Vaccine against Poliomyelitis.

J Virol 2018 09 16;92(17). Epub 2018 Aug 16.

Department of Veterinary Medicine and Virginia-Maryland College of Veterinary Medicine, University of Maryland, College Park, Maryland, USA

The poliovirus eradication initiative has spawned global immunization infrastructure and dramatically decreased the prevalence of the disease, yet the original virus eradication goal has not been met. The suboptimal properties of the existing vaccines are among the major reasons why the program has repeatedly missed eradication deadlines. Oral live poliovirus vaccine (OPV), while affordable and effective, occasionally causes the disease in the primary recipients, and the attenuated viruses rapidly regain virulence and can cause poliomyelitis outbreaks. Read More

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September 2018
20 Reads

Postpolio syndrome and the late effects of poliomyelitis. Part 1. pathogenesis, biomechanical considerations, diagnosis, and investigations.

Muscle Nerve 2018 May 12. Epub 2018 May 12.

Sunnybrook Health Sciences Centre, Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, Canada.

Postpolio syndrome (PPS) is characterized by new muscle weakness and/or muscle fatigability that occurs many years after the initial poliomyelitis illness. Many theories exist regarding the pathogenesis of PPS, which remains incompletely understood. In contrast, the late effects of poliomyelitis are often a consequence of biomechanical alterations that occur as a result of polio-related surgeries, musculoskeletal deformities, or weakness. Read More

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May 2018
1 Read

Ultrasound-Guided Carpal Tunnel Release Using Dynamic Expansion of the Transverse Safe Zone in a Patient With Postpolio Syndrome: A Case Report.

PM R 2018 Oct 6;10(10):1115-1118. Epub 2018 Mar 6.

Department of Neurosurgery, University of Michigan, Ann Arbor, MI(§).

The prevalence of carpal tunnel syndrome (CTS) in patients with postpolio syndrome occurs at a rate of 22%. Irrespective of those with CTS, 74% of postpolio patients weight bear through their arms for ambulation or transfers. As open carpal tunnel release is performed along the weight-bearing region of the wrist, their functional independence may be altered while recovering. Read More

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October 2018
4 Reads

Restless legs syndrome is highly prevalent in patients with postpolio syndrome.

Sleep Med 2018 Jan 22;41:112. Epub 2017 Oct 22.

Neurology, Department of Systems Medicine, Tor Vergata University and Hospital, Rome, Italy.

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January 2018
4 Reads

Systematic review of the evidence on orthotic devices for the management of knee instability related to neuromuscular and central nervous system disorders.

BMJ Open 2017 Sep 5;7(9):e015927. Epub 2017 Sep 5.

Kingston University, Kingston-Upon-Thames, London, UK.

Objectives: To assess the effectiveness of orthotic devices for the management of instability of the knee in adults with a neuromuscular disorder or central nervous system disorder.

Design: A systematic review of primary studies.

Setting: Community. Read More

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September 2017
21 Reads

Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews.

Cochrane Database Syst Rev 2017 04 24;4:CD011279. Epub 2017 Apr 24.

Division of Population Health Sciences, University of Dundee, Dundee, UK.

Background: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%. Read More

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April 2017
11 Reads

A patient with postpolio syndrome developed cauda equina syndrome after neuraxial anesthesia: A case report.

J Clin Anesth 2017 Feb 27;37:49-51. Epub 2016 Dec 27.

Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, ROC. Electronic address:

Combined spinal anesthesia and postoperative epidural analgesia is widely used in orthopedic surgery. Uncommon but serious neurologic complications of neuraxial anesthesia (NA) include direct trauma during needle or catheter insertion, central nervous system infections, and neurotoxicity of local anesthetics. Cauda equina syndrome (CES) is a rare complication after NA but can result in severe neurologic deterioration that may require surgical intervention. Read More

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February 2017
4 Reads

Health related quality of life in Turkish polio survivors: impact of post-polio on the health related quality of life in terms of functional status, severity of pain, fatigue, and social, and emotional functioning.

Rev Bras Reumatol Engl Ed 2017 Jan - Feb;57(1):1-7. Epub 2015 Mar 10.

Ankara Numune Training and Research Hospital, Department of Physical Medicine and Rehabilitation, Ankara, Turkey.

Objective: To determine the impact of postpolio-syndrome on quality of life in polio survivors.

Methods: Forty polio survivors were included in the study. Twenty-one patients fulfilling the Halstead's postpolio-syndrome criteria participated in postpolio-syndrome group. Read More

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March 2015
13 Reads

Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews.

Cochrane Database Syst Rev 2017 01 14;1:CD011279. Epub 2017 Jan 14.

Division of Population Health Sciences, University of Dundee, Dundee, UK.

Background: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%. Read More

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January 2017
45 Reads

Growing Older With a Physical Disability: A Special Application of the Successful Aging Paradigm.

J Gerontol B Psychol Sci Soc Sci 2017 Mar;72(2):290-299

Department of Rehabilitation Medicine, University of Washington, Seattle.

Objectives: In the United States, the average age of people living with early-acquired physical disabilities is increasing. This cohort is said to be aging with disability and represents a unique population among older adults. Given recent policy efforts designed to merge aging and disability services, it is critical that models of "successful aging" include and are relevant to this population. Read More

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March 2017
7 Reads

No Reduction of Severe Fatigue in Patients With Postpolio Syndrome by Exercise Therapy or Cognitive Behavioral Therapy: Results of an RCT.

Neurorehabil Neural Repair 2016 06 7;30(5):402-10. Epub 2015 Aug 7.

University of Amsterdam, Amsterdam, The Netherlands.

Background: People with postpolio syndrome (PPS) commonly experience severe fatigue that persists over time and negatively affects functioning and health-related quality of life (HRQoL).

Objectives: To study the efficacy of exercise therapy (ET) and cognitive behavioral therapy (CBT) on reducing fatigue and improving activities and HRQoL in patients with PPS.

Methods: We conducted a multicenter, single-blinded, randomized controlled trial. Read More

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June 2016
32 Reads

Response to the Letter to the Editor on "Review of Secondary Health Conditions in Postpolio Syndrome".

Am J Phys Med Rehabil 2015 Oct;94(10):e92-3

University of Washington Seattle, Washington.

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October 2015
1 Read

Treatment for postpolio syndrome.

Cochrane Database Syst Rev 2015 May 18(5):CD007818. Epub 2015 May 18.

Department of Rehabilitation, University of Amsterdam Academic Medical Center, PO Box 22660, Amsterdam, North Holland, Netherlands, 1100 DD.

Background: Postpolio syndrome (PPS) may affect survivors of paralytic poliomyelitis and is characterised by a complex of neuromuscular symptoms leading to a decline in physical functioning. The effectiveness of pharmacological treatment and rehabilitation management in PPS is not yet established. This is an update of a review first published in 2011. Read More

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May 2015
4 Reads

Does a subgroup of postpolio patients need different management?

Authors:
Ruth Bridgens

Disabil Health J 2015 Jul 10;8(3):305-8. Epub 2015 Mar 10.

66 High Street, Marshfield, Chippenham, Wiltshire SN 14 8LP, UK. Electronic address:

Throughout the 30 years of postpolio syndrome (PPS) research, there have been many puzzling anomalies in the data and not enough information to make sense of them. It is therefore welcome that Winberg et al have examined physical activity in relation to life satisfaction, sex and age. They hypothesized that activity would decrease with age and found the opposite. Read More

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July 2015
2 Reads

Intravenous immunoglobulin for postpolio syndrome: a systematic review and meta-analysis.

BMC Neurol 2015 Mar 22;15:39. Epub 2015 Mar 22.

Department of Neurology, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan.

Background: Postpolio syndrome (PPS) is characterized by progressive disabilities that develop decades after prior paralytic poliomyelitis. Because chronic inflammation may be the process underlying the development of PPS, immunomodulatory management, such as intravenous immunoglobulin (IVIg) administration, may be beneficial.

Methods: We performed a systematic review and meta-analysis of published randomized controlled trials (RCTs) and prospective studies that evaluated the efficacy of IVIg in managing PPS. Read More

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March 2015
2 Reads

Feasibility of Lung Volume Recruitment in Early Neuromuscular Weakness: A Comparison Between Amyotrophic Lateral Sclerosis, Myotonic Dystrophy, and Postpolio Syndrome.

PM R 2015 Jul 3;7(7):677-84. Epub 2015 Apr 3.

Meakins-Christie Laboratories, McGill University and Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada(∗∗); Respiratory Division, McGill University Health Centre, Montreal, Quebec, Canada.

Background: Lung volume recruitment (LVR) is a cough assistance technique used in persons with neuromuscular disorders (NMDs), most typically in those requiring noninvasive ventilation (NIV). Whether it may be useful in persons with NMDs who have milder respiratory impairment is unknown.

Objective: To assess the feasibility, impact on quality of life (QOL), and preliminary physiological effects of daily LVR in different categories of persons with NMDs who have an early stage of respiratory impairment. Read More

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July 2015
8 Reads

[Socio-medical profile of post-polio syndrome patients in center east of Tunisia].

Tunis Med 2014 Aug-Sep;92(8-9):556-9

Background: The diagnosis of the post polio syndrome is purely clinic. It occurs few decade after poliomyelitis. It associates recent appearance or progressive worsening of muscular weakness, pain, muscular fatigue or atrophy. Read More

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May 2015
5 Reads

Quality of Life among Persons with Physical Disability in Udupi Taluk: A Cross Sectional Study.

J Family Med Prim Care 2015 Jan-Mar;4(1):69-73

Department of Public Health, Manipal University, Manipal, Karnataka, India.

Background: Disability is not just a health problem or attribute of individuals, but it reflects the problems individuals experience in their interaction with society and physical movements. Disabled persons remain neglected part of society and they also experience various barriers due to restriction of participation.

Objectives: The aim was to assess the quality of life (QOL) of physically disabled persons, the impact of physical disability on activities of daily living (ADL) and to study the awareness about laws and facilities available for disabled persons. Read More

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March 2015
31 Reads

[Health related quality of life in Turkish polio survivors: impact of post-polio on the health related quality of life in terms of functional status, severity of pain, fatigue, and social, and emotional functioning].

Rev Bras Reumatol 2015 Feb 7. Epub 2015 Feb 7.

Departamento de Medicina e Reabilitação Física, Ankara Numune Training and Research Hospital, Ancara, Turquia.

Objective: To determine the impact of postpolio-syndrome on quality of life in polio survivors.

Methods: Forty polio survivors were included in the study. Twenty-one patients fulfilling the Halstead's postpolio-syndrome criteria participated in postpolio-syndrome group. Read More

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February 2015
15 Reads

Effects of a Tailored Positive Psychology Intervention on Well-Being and Pain in Individuals With Chronic Pain and a Physical Disability: A Feasibility Trial.

Clin J Pain 2016 Jan;32(1):32-44

*Department of Rehabilitation Medicine, University of Washington, Seattle, WA †Swiss Paraplegic Research, Nottwil, Switzerland.

Objectives: To determine the feasibility, acceptability, and efficacy of a computer-based positive psychology intervention in individuals with a physical disability and chronic pain.

Methods: Individuals with spinal cord injury, multiple sclerosis, neuromuscular disease, or postpolio syndrome and chronic pain were randomly assigned to a positive psychology or a control condition. Participants in the intervention group were instructed to practice 4 personalized positive psychology exercises. Read More

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January 2016
48 Reads

Long-standing poliomyelitis and psychological health.

Disabil Rehabil 2015 27;37(24):2233-7. Epub 2015 Feb 27.

a Department of Physical Medicine and Rehabilitation , Hadassah-Hebrew University Medical Center , Jerusalem , Israel.

Objective: To compare the psychological health of the individuals with long-standing poliomyelitis, with or without post-polio syndrome (PPS), to the general population and to identify the role of work as well as other variables with regard to their psychological health.

Design: A cross-sectional study.

Subjects: One hundred and ninety-five polio patients attending postpolio clinic in Jerusalem. Read More

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July 2016
6 Reads

Falls among adults aging with disability.

Arch Phys Med Rehabil 2015 Mar 19;96(3):464-71. Epub 2014 Oct 19.

Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA.

Objective: To investigate the prevalence of and risk factors for falling among individuals aging with multiple sclerosis (MS), muscular dystrophy (MD), postpolio syndrome (PPS), and spinal cord injury (SCI).

Design: Cross-sectional survey data from 2009 to 2010 were analyzed. We used forward logistic regression models to examine whether risk factors such as age, sex, mobility level, years since diagnosis, vision, balance, weakness, number of comorbid conditions, and physical activity could distinguish participants who reported falling from those who did not. Read More

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March 2015
8 Reads

Review of secondary health conditions in postpolio syndrome: prevalence and effects of aging.

Am J Phys Med Rehabil 2015 Feb;94(2):139-45

From the Department of Rehabilitation Medicine, University of Washington, Seattle.

Objective: This study sought to better understand the prevalence and the severity of secondary health conditions in individuals with postpolio syndrome (PPS) as well as the association between these conditions and aging.

Design: A scoping literature review was conducted searching electronic databases for studies published from 1986 to 2011. The scoping review provided information regarding the prevalence and associations of secondary health conditions in PPS with age or other duration-related variables. Read More

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February 2015
7 Reads

Vaccine-derived poliomyelitis and postpolio syndrome: an Italian Cutter Incident.

JRSM Open 2014 Jan 7;5(1):2042533313511241. Epub 2014 Jan 7.

St Camillo Hospital of Rome, Rome 00152, Italy.

Post-polio syndrome is a condition characterized by increased muscle weakness, atrophy, fatigue and pain developing several years after the acute polio event. We describe a 52-year-old patient who experienced post-polio syndrome; he had contracted acute paralytic poliomyelitis at 12 months of age, shortly after the third dose of Salk polio vaccine. Read More

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January 2014
22 Reads

Normal serum levels of immune complexes in postpolio patients.

Results Immunol 2014 18;4:54-7. Epub 2014 Jun 18.

Division of Rehabilitation Medicine, Department of Clinical Sciences, Karolinska Institutet, Danderyd University Hospital, Stockholm, Sweden.

Objective: The pathophysiology of the postpolio syndrome is not fully understood. Increased cytokine levels in cerebrospinal fluid and peripheral blood indicate a systemic inflammatory process. Decreased cytokine levels and the clinical effect of intravenous immunoglobulin treatment further indicate an inflammatory/immunological pathogenesis. Read More

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July 2014
1 Read

Alterations in muscle proteome of patients diagnosed with amyotrophic lateral sclerosis.

J Proteomics 2014 Aug 17;108:55-64. Epub 2014 May 17.

Department of Chemistry-BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden. Electronic address:

Unlabelled: Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive muscle paralysis. Currently clinical tools for ALS diagnostics do not perform well enough and their improvement is needed. The objective of this study was to identify specific protein alterations related to the development of ALS using tiny muscle biopsies. Read More

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August 2014
6 Reads

Few patients with neurodegenerative disorders require spinal surgery.

Surg Neurol Int 2014 16;5(Suppl 3):S81-7. Epub 2014 Apr 16.

Director of Winthrop Comprehensive Multiple Sclerosis Care Center, Mineola, Winthrop University Hospital, Mineola, NY, 11501 and Clinical Professor of Neurology, Stony Brook, NY, USA.

Background: Few patients with neurodegenerative disorders (ND) (e.g., Multiple Sclerosis (MS), Amyotrophic Lateral Sclerosis (ALS), and Postpolio Syndrome (PPS)) require spinal surgery. Read More

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May 2014
11 Reads

Complications and outcomes of complex spine reconstructions in poliomyelitis-associated spinal deformities: a single-institution experience.

Spine (Phila Pa 1976) 2014 Jul;39(15):1211-6

From the Departments of *Orthopaedic Surgery and †Neurological Surgery, Washington University in St Louis, School of Medicine, St Louis, MO.

Study Design: Retrospective case series.

Objective: To share our institutional experience with spinal reconstruction for deformity correction in patients with a history of poliomyelitis.

Summary Of Background Data: Polio and postpolio syndrome are not uncommonly related to a paralytic spinal deformity. Read More

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July 2014
11 Reads

Determining the anaerobic threshold in postpolio syndrome: comparison with current guidelines for training intensity prescription.

Arch Phys Med Rehabil 2014 May 31;95(5):935-40. Epub 2014 Jan 31.

Department of Rehabilitation, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

Objectives: To determine whether the anaerobic threshold (AT) can be identified in individuals with postpolio syndrome (PPS) using submaximal incremental exercise testing, and to compare current guidelines for intensity prescription in PPS with the AT.

Design: Cohort study.

Setting: Research laboratory. Read More

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May 2014
4 Reads

Assessment of subjective and motor fatigue in Polio survivors, attending a Postpolio clinic, comparison with healthy controls and an exploration of clinical correlates.

Physiother Theory Pract 2014 May 16;30(4):229-35. Epub 2013 Dec 16.

Department of Physiotherapy, Beaumont Hospital , Beaumont, Dublin , Ireland .

Purpose: Polio survivors experience declining mobility, pain and fatigue. The extent of motor fatigue and its impact on mobility and quality of life, in addition to other commonly reported impairments requires evaluation.

Methods: An observational, case-control, cross-sectional design was used to assess 30 Polio survivors and 30 age- and sex-matched controls. Read More

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May 2014
1 Read

[Polio paralytic. New problems: postpolio syndrome].

Authors:
Jesús Esteban

Rev Esp Salud Publica 2013 Sep-Oct;87(5):517-22

Unidad de Esclerosis lateral amiotrófica, Sección Neuromuscular, Servicio de Neurología, Hospital Universitario 12 de Octubre, Madrid, España.

In 1875 M. Raymond described a progressive muscle wasting and weakness in 3 individuals survivors of childhood acute poliomyelitis. Jean-Martin Charcot suggested that the initial injury should let these guys neurons more sensitive to develop posterior spinal diseases and new weakness was the result of overuse of the affected muscles. Read More

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March 2014
2 Reads

Brain volume and fatigue in patients with postpoliomyelitis syndrome.

PM R 2014 Mar 20;6(3):215-20. Epub 2013 Sep 20.

Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University Health Centre, Montreal, Quebec, Canada(#).

Background: Acute paralytic poliomyelitis is associated with encephalitis. Early brain inflammation may produce permanent neuronal injury with brain atrophy, which may result in symptoms such as fatigue. Brain volume has not been assessed in postpoliomyelitis syndrome (PPS). Read More

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March 2014
5 Reads

Psychometric properties of fatigue severity and fatigue impact scales in postpolio patients.

Int J Rehabil Res 2013 Dec;36(4):339-45

aDepartment of Physical Medicine and Rehabilitation, Şişli Etfal Teaching Hospital, Istanbul bDepartment of Physical Medicine and Rehabilitation, Medical Faculty of Ege University, Bornova-Izmir, Turkey.

We evaluate the reliability, validity, and responsiveness of the Fatigue Severity Scale (FSS) and the Fatigue Impact Scale (FIS) and to determine whether these scales are potentially applicable for measuring fatigue in postpolio patients (PPS). After the Turkish adaptation of FSS and FIS using a forward-backward procedure, the scales were administered to 48 PPS patients without additional health problems that may induce fatigue. Reliability studies were carried out by determination of intraclass correlation coefficient and internal consistency by the Cronbach-α coefficient. Read More

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December 2013
5 Reads

Prevalence and impact of pain in adults aging with a physical disability: comparison to a US general population sample.

Clin J Pain 2014 Apr;30(4):307-15

*Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA †Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL ‡Center for Health Outcomes Research, United BioSource Corporation, Bethesda MD.

Objectives: To describe rates of pain and pain interference in a large sample of adults aging with long-standing physical disabilities, relative to a normative US population sample.

Methods: Self-report survey data was collected for a sample of 1877 individuals with spinal cord injury, neuromuscular disease, postpolio syndrome, or multiple sclerosis. Rates of pain severity and pain interference in these samples were then compared with those taken from a large normative sample (>20,000) collected through the NIH Patient Reported Outcomes Measurement Information System (PROMIS). Read More

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April 2014
2 Reads

A randomized controlled trial of IV immunoglobulin in patients with postpolio syndrome.

J Neurol Sci 2013 Jul 15;330(1-2):94-9. Epub 2013 May 15.

Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Italy.

Objective: To investigate in a single-center randomized control trial whether a single IVIg course improves short-term outcome in patients with postpolio syndrome (PPS).

Methods: Fifty-one patients with PPS were randomly allocated to receive 2g/kg IVIg body weight or placebo infused over 5 consecutive days. The primary endpoint was health-related quality of life (HRQoL) limited to the physical component score (PCS) in the Short-Form-36 (SF-36). Read More

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July 2013
8 Reads
2 Citations
2.470 Impact Factor

Test-retest reliability of the 6-min walk test in patients with postpolio syndrome.

Int J Rehabil Res 2013 Jun;36(2):140-5

Department of Clinical Sciences, Division of Rehabilitation Medicine, Karolinska Institutet, Danderyds University Hospital, Stockholm, Sweden.

This study describes the test-retest reliability of the 6-min walk test (6MWT) and evaluates the possibility to perform the test three times on the same day in patients with postpolio syndrome (PPS). This was an intrarater test-retest reliability study. A total of 23 PPS patients (nine men, 14 women), mean age 67 years, participated in the study. Read More

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June 2013
1 Read

Self-reported depression and physical activity in adults with mobility impairments.

Arch Phys Med Rehabil 2013 Apr 16;94(4):731-6. Epub 2012 Nov 16.

Group Health Research Institute, Seattle, WA 98101, USA.

Objective: To test hypothesized associations between depression and physical activity among adults with multiple sclerosis (MS), spinal cord injury (SCI), muscular dystrophy (MD), and postpolio syndrome (PPS).

Design: Cross-sectional survey.

Setting: Survey responses collected from individuals in the Washington state area (participants with SCI) and across the United States (participants with MS, MD, and PPS). Read More

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Anesthetic implications of postpolio syndrome: new concerns for an old disease.

AANA J 2012 Oct;80(5):356-61

Saint Louis University Hospital, St Louis, Missouri, USA.

Poliomyelitis was pandemic in the United States and much of the world in the first half of the 20th century. The uses of polio vaccines have essentially eradicated the disease in the United States today. But poliovirus infection survivors who had experienced a paralytic attack can see a return of some symptoms, which is a syndrome called postpolio syndrome (PPS). Read More

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October 2012
2 Reads

Health-related quality of life and supportive care in patients with rare long-term neurological conditions.

Qual Life Res 2013 Aug 23;22(6):1231-8. Epub 2012 Sep 23.

School of Health and Population Sciences, University of Birmingham, Birmingham, UK.

Purpose: Rare long-term neurological conditions (rLTNCs) may have significant impact on patients' health-related quality of life (HRQL); however, evidence is sparse. We assessed HRQL and access to supportive care in patients with rLTNCs.

Methods: Survey of patients with rare rLTNCs (motor neurone disease, Huntington's disease, cerebellar ataxia, progressive supranuclear palsy, multiple system atrophy, Charcot-Marie-Tooth disease and postpolio syndrome) to assess current access to health and social care, and HRQL using the Euroqol EQ-5D. Read More

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Effects of Dăoyĭn Qìgōng in postpolio syndrome patients with cold intolerance.

Arq Neuropsiquiatr 2012 Sep;70(9):680-5

Department of Neurology and Neurosurgery, Department of Clinical Neurology, Division of Neuromuscular Disease Research, Clinic of Traditional Chinese Medicine, Universidade Federal de São Paulo, São Paulo SP, Brazil.

Unlabelled: Postpolio syndrome (PPS) is characterized by progressive muscle weakness due to former infection with poliomyelitis and can be associated with other symptoms such as cold intolerance (CI). Dăoyĭn Qìgōng (DQ) is a technique in Traditional Chinese Medicine that impacts the circulation of energy and blood.

Objective: It was to verify the effects of DQ in PPS patients complaining of cold intolerance. Read More

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September 2012
3 Reads

Hypothyroid myopathy mimicking postpolio syndrome.

BMJ Case Rep 2012 Aug 24;2012. Epub 2012 Aug 24.

Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, Uttar Pradesh, India.

Hypothyroidism can have diverse neurological manifestations. Myopathy may rarely be the sole manifestation of autoimmune thyroiditis. We hereby report an atypical manifestation of severe hypothyroidism in a middle-aged woman with childhood onset of paralytic polio involving her right leg presenting with a recent onset of increased weakness in the right leg mimicking postpolio syndrome. Read More

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August 2012
2 Reads

Living with polio and postpolio syndrome in the United Kingdom.

Scand J Caring Sci 2013 Jun 22;27(2):238-45. Epub 2012 Jul 22.

School of Health Science and Social Care, Brunel University, Kingston Lane, Uxbridge, Middlesex, London, UK.

The term Postpolio Syndrome (PPS) is used to describe new and late manifestations of poliomyelitis that occur later in life in polio survivors. Polio had been eradicated in the United Kingdom (UK) and most of Europe, although this is not the case in all countries. Research in this area has tended to focus upon the impact of polio and PPS on health status and functional health rather than its overall effect on people's lives. Read More

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June 2013
2 Reads

Evidence-based guideline: intravenous immunoglobulin in the treatment of neuromuscular disorders: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.

Neurology 2012 Mar;78(13):1009-15

Yale University/VA Connecticut Healthcare System, New Haven, CT, USA.

Objective: To assess the evidence for the efficacy of IV immunoglobulin (IVIg) to treat neuromuscular disorders.

Methods: The MEDLINE, Web of Science, and EMBASE databases were searched (1966-2009). Selected articles were rated according to the American Academy of Neurology's therapeutic classification of evidence scheme; recommendations were based on the evidence level. Read More

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Six patient-reported outcome measurement information system short form measures have negligible age- or diagnosis-related differential item functioning in individuals with disabilities.

Arch Phys Med Rehabil 2012 Jul 2;93(7):1289-91. Epub 2012 Mar 2.

Department of Medical Social Sciences, Northwestern University, Chicago, IL.

Objective: To evaluate the measurement invariance of 6 self-report measures selected for an ongoing longitudinal study of individuals with spinal cord injury, muscular dystrophy, postpolio syndrome, and multiple sclerosis.

Design: Participants completed and returned by mail surveys that included the targeted self-report measures. Ordinal logistic regressions methods were applied to evaluate items for differential item functioning (DIF) by diagnosis and age range. Read More

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July 2012
1 Read

Provocative poliomyelitis causing postpolio residual paralysis among select communities of two remote villages of North Karnataka in India: a community survey.

Indian J Public Health 2011 Oct-Dec;55(4):309-12

Department of Physiotherapy, Kasturba Medical College, Mangalore, India.

Intramuscular injections can provoke muscular paralysis especially, if the child has had exposure to polio virus. The purpose of the study was to determine the association with known risk factors for motor disabilities in two remote villages of North Karnataka (India), where an increased number of disabled people among select communities had been reported. A community based survey was conducted. Read More

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Clinical utility of sensory nerve conduction of medial femoral cutaneous nerve.

Muscle Nerve 2012 Feb;45(2):195-9

Department of Neurology, University of Alabama at Birmingham, Veterans Affairs Medical Center, University Station, Birmingham, Alabama 35294, USA.

Introduction: In this investigation we report on the clinical utility of sensory nerve conduction studies of the medial femoral cutaneous (MFC) nerve.

Methods: Sensory nerve conduction of the MFC nerve was assessed in 22 patients for whom this test was considered clinically necessary.

Results: MFC nerve conduction was abnormal in 4 cases of MFC neuropathy. Read More

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February 2012