10,025 results match your criteria Postpartum Depression


Feelings about pregnancy and mother-infant bonding as predictors of persistent psychological distress in the perinatal period: The Japan Environment and Children's Study.

J Psychiatr Res 2021 May 30;140:132-140. Epub 2021 May 30.

Hyogo Regional Center for the Japan Environment and Children's Study, Hyogo College of Medicine, Nishinomiya, Japan; Department of Public Health, Hyogo College of Medicine, Nishinomiya, Japan. Electronic address:

Feelings about pregnancy and mother-infant bonding are associated with maternal mental health before and after childbirth. The current study examined factors associated with persistent distress at 12 months after childbirth among mothers with psychological distress in the first trimester, using data from the Japan Environment and Children's Study (JECS). Feelings about pregnancy were assessed using a questionnaire in the first trimester, and maternal mental health was assessed using the Kessler 6 (K6) in the first trimester and at 12 months after childbirth. Read More

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Maternal depression and its correlates: A longitudinal study.

J Pak Med Assoc 2021 Jun;71(6):1618-1622

Department of Community and Family Medicine, Shifa College of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan.

Objective: To estimate the burden of antenatal and postpartum depression, and to explore possible predictors of perinatal depression.

Methods: The longitudinal study was conducted at the Department of Obstetrics and Gynaecology, Shifa International Hospital and its Community Healthcare centre in Islamabad, Pakistan, from October 2018 to May 2019, and comprised women in their third trimester of pregnancy. Socioeconomic and obstetrical history was recorded on a proforma, and the Edinburgh Postnatal Depression Scale was used for screening of depression. Read More

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Bibliometrics and Visual Analysis of the Research Status and Trends of Postpartum Depression From 2000 to 2020.

Front Psychol 2021 24;12:665181. Epub 2021 May 24.

Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.

The purpose of this study was to evaluate the international scientific output on postpartum depression (PPD) research during 2000-2020 through a bibliometric analysis and to explore research hotspots, frontiers, and trends in the field of postpartum depression. We searched the Web of Science Core Collection for publications on postpartum depression published between 2000 and 2020. CiteSpace, gCluto, and other software applications were used to analyze the data by year, journal, and country. Read More

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The Effect of Analgesia and Anesthesia on Postpartum Depression.

Adv Anesth 2020 Dec;38:157-165

Department of Anesthesia, Beilinson Hospital, Petach Tikvah, Israel; Affiliated with Saklar Medical School, Tel Aviv University. Electronic address:

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December 2020

Trajectories of pain during pregnancy predict symptoms of postpartum depression.

Pain Rep 2021 Jul-Aug;6(2):e933. Epub 2021 Jun 3.

Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX, USA.

Introduction: Postpartum depression imparts a significant and long-lasting burden on maternal and child health. Successful prevention or early detection of postpartum depression will rely on the identification of early risk factors. Pain during pregnancy (before childbirth) is a key potential predictor of postpartum depression risk. Read More

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Effect of a lay counselor-delivered integrated maternal mental health and early childhood development group-based intervention in Northern Ghana: a cluster-randomized controlled trial.

Glob Ment Health (Camb) 2021 26;8:e18. Epub 2021 May 26.

Catholic Relief Services Head Quarters, Baltimore, MD, USA.

Background: Caregiver mental health is linked to early childhood development, yet more robust evidence of community-based interventions to prevent maternal depression and optimize socio-emotional development of young children is needed. Objectives of this cluster-randomized controlled trial (cRCT), based in Northern Ghana, are to assess the impact of the lay counselor-delivered, group-based Integrated Mothers and Babies Course and Early Childhood Development (iMBC/ECD) program on (1) the mental health of mothers of children under age 2; and (2) the socio-emotional development of their children.

Methods: This cRCT randomized 32 women's groups - 16 received iMBC/ECD content (intervention) and 16 received general health education content (control). Read More

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Influence of parental competence on postpartum depression mediated via negative thoughts: moderating role of type of delivery.

Women Health 2021 Jun 8:1-8. Epub 2021 Jun 8.

Department of Psychology, University of Sargodha, Sargodha, Pakistan.

The present study intended to explore and compare the mediating role of negative thoughts between the sense of parental competence and postpartum depression in postpartum mothers who gave birth to their baby either through vaginal or cesarean delivery. A purposive sample of 170 women suffering from postpartum depression was recruited from different hospitals in Gujrat, Pakistan. Urdu versions of the Parenting Sense of Competency Scale, Automatic Thoughts Questionnaire, and Edinburgh Postnatal Depression Scale were used to measure the focal constructs of the study. Read More

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Postpartum depression and family function in Chinese women within 1 year after childbirth: A cross-sectional study.

Res Nurs Health 2021 Jun 8. Epub 2021 Jun 8.

Department of Community Nursing, Xiangya School of Nursing, Central South University, Changsha, China.

Family-related factors are reported to influence the development of postpartum depression (PPD), but limited studies have considered the role of family function in this condition. This study aimed to describe the proportion of people with probable or suspected PPD and to determine the relationships among PPD, family function, and obstetric factors. A cross-sectional study was conducted with 630 women who attended six integrated teaching and scientific research communities in Changsha, China. Read More

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Early postnatal discharge from hospital for healthy mothers and term infants.

Cochrane Database Syst Rev 2021 Jun 8;6:CD002958. Epub 2021 Jun 8.

Murdoch Children's Research Institute, Parkville, Australia.

Background: Length of postnatal hospital stay has declined dramatically in the past 50 years. There is ongoing controversy about whether staying less time in hospital is harmful or beneficial. This is an update of a Cochrane Review first published in 2002, and previously updated in 2009. Read More

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Evaluation of salivary melatonin concentrations as a circadian phase maker of morning awakening and their association with depressive mood in postpartum mothers.

Chronobiol Int 2021 Jun 8:1-12. Epub 2021 Jun 8.

Department of Maternity Nursing, Akita University Graduate School of Medicine and Faculty of Medicine, School of Health Science, Akita-shi, Japan.

The disruption of circadian rhythm is closely related to mood disorders in night-shift workers, and a similar situation may occur in postpartum mothers. However, the situations of postpartum mothers remain largely unknown because of a lack of an appropriate circadian phase marker in the clinical setting. This study aimed to evaluate whether salivary melatonin concentration at awakening can identify misalignment between awakening time and the biological clock system, which might be associated with depressive mood in some mothers. Read More

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Postpartum mental illness during the COVID-19 pandemic: a population-based, repeated cross-sectional study.

CMAJ 2021 06;193(23):E835-E843

Women's College Research Institute (Vigod, Brown, Barker, Wright), Women's College Hospital; Department of Psychiatry (Vigod, Brown, Barker, Wright, Grigoriadis), Temerty Faculty of Medicine, University of Toronto; ICES Central (Vigod, Brown, Huang, Fung, Barker, Gozdyra, Moineddin); Institute for Health Policy, Management and Evaluation (Vigod, Brown, Barker, Hussain-Shamsy, Moineddin), Dalla Lana School of Public Health, University of Toronto; Department of Health and Society (Brown), University of Toronto Scarborough; Lawrence S. Bloomberg Faculty of Nursing (Dennis), University of Toronto; Sunnybrook Health Sciences Centre (Grigoriadis), Toronto, Ont.; Department of Obstetrics and Gynecology (Corsi, Walker), University of Ottawa, Ottawa, Ont.; Department of Family & Community Medicine (Moineddin), Faculty of Medicine, University of Toronto, Toronto, Ont.

Background: It is unclear whether the clinical burden of postpartum mental illness has increased during the COVID-19 pandemic. We sought to compare physician visit rates for postpartum mental illness in Ontario, Canada, during the pandemic with rates expected based on prepandemic patterns.

Methods: In this population-based, repeated cross-sectional study using linked health administrative databases in Ontario, Canada, we used negative binomial regression to model expected visit rates per 1000 postpartum people for March-November 2020 based on prepandemic data (January 2016-February 2020). Read More

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Maternal low-intensity psychosocial telemental interventions in response to COVID-19 in Qatar: study protocol for a randomized controlled trial.

Trials 2021 Jun 7;22(1):382. Epub 2021 Jun 7.

Primary Health Care Corporation, Doha, Qatar.

Introduction: As COVID-19 is spreading, new psychological health problems are suspected to be emerging among pregnant women. Higher maternal mental health distress, including perinatal anxiety, depression, and COVID-19-specific phobia, is supposed to be increasing during the pandemic, which impacts pregnant women's health and their infants and calls for intervention. Due to the social distancing protocols posed by the pandemic, telemental health interventions have fast become the most common form of psychosocial support for maternal mental health. Read More

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Effectiveness of the CenteringPregnancy program on maternal and birth outcomes: A systematic review and meta-analysis.

Int J Nurs Stud 2021 May 20;120:103981. Epub 2021 May 20.

Emory University Nell Hodgson Woodruff School of Nursing, 1520 Clifton Road, Atlanta, GA 30322, USA. Electronic address:

Background: The World Health Organization has emphasized the critical role of prenatal care in achieving the Millennium Development Goals to reduce child and maternal mortality. The CenteringPregnancy program is a widely recognized model of prenatal care. Several countries have attempted to implement the program in prenatal care practice; however, its effectiveness on maternal and birth outcomes has not been systematically evaluated and analyzed. Read More

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Liver transcriptome response to periparturient hormonal and metabolic changes depends on the postpartum occurrence of subacute ruminal acidosis in Holstein cows.

Physiol Genomics 2021 06 7. Epub 2021 Jun 7.

Graduate School of Veterinary Sciences, Iwate University, Japan.

We investigated changes in rumen fermentation, peripheral blood metabolites and hormones, and hepatic transcriptomic dynamics in Holstein cows with and those without subacute ruminal acidosis (SARA) during the periparturient period. Sixteen multiparous Holstein cows were categorized in the SARA (n-=-8) or non-SARA (n-=-8) groups depending on whether they developed SARA during the 2 weeks after parturition. Reticulo-ruminal pH was measured continuously throughout the study. Read More

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The Indirect Effect of Parental Intolerance of Uncertainty on Perinatal Mental Health via Mindfulness During COVID-19.

Mindfulness (N Y) 2021 Jun 2:1-10. Epub 2021 Jun 2.

Department of Psychology, University of Illinois at Urbana-Champaign, Psychology Building, 603 E Daniel St, Champaign, IL 61820 USA.

Objectives: The COVID-19 pandemic is associated with mental health difficulties, especially during pregnancy and early postpartum. Intolerance of uncertainty (IU) and reduced capacity for mindfulness-a protective factor for child-bearers-may be particularly relevant factors driving mental health problems given the unpredictable nature of the pandemic. The current study aims to shed light on modifiable paths to perinatal psychological distress by testing whether there is an indirect effect of IU on psychological symptoms through a perceived reduction in mindfulness during the pandemic. Read More

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Associations Between Sleep and Mental Health Among Latina Adolescent Mothers: The Role of Social Support.

Front Psychol 2021 21;12:647544. Epub 2021 May 21.

Department of Psychological Sciences, University of California, Merced, Merced, CA, United States.

Adolescent mothers experience poorer sleep than adult mothers, and Latina adolescent mothers are at greater risk of postpartum depression compared with other racial/ethnic groups. However, social support may be protective against the negative effects of poor sleep in this population. The current study examined (1) associations between the quality and quantity of Latina adolescent mothers' sleep and mental health (depressive symptoms and anxiety), and (2) whether social support buffered the effects of poor sleep on mental health. Read More

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Brexanolone to Treat Postpartum Depression in Adult Women.

Psychopharmacol Bull 2021 Mar;51(2):115-130

Cornett, PhD, Rando, BS, Labbé, Kaye, MD, PhD, Department of Anesthesiology, LSU Health Shreveport, Shreveport, LA. Perkins, BS, LSU School of Medicine, LSUHSC New Orleans, New Orleans, LA. Kaye, Pharm.D., FASCP, FCPhA, Department of Pharmacy Practice, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA. Viswanath, MD, Department of Anesthesiology, LSU Health Shreveport, Shreveport, LA, Valley Anesthesiology and Pain Consultants - Envision Physician Services, Phoenix, AZ, University of Arizona College of Medicine - Phoenix, Department of Anesthesiology, Phoenix, AZ, University School of Medicine, Department of Anesthesiology, Omaha, NE. Urits, MD, Department of Anesthesiology, LSU Health Shreveport, Shreveport, LA, Beth Israel Deaconess Medical Center, Department of Anesthesia, Critical Care, and Pain Medicine, Boston, MA.

ZULRESSO (Brexanolone) is a novel FDA-approved treatment for moderate-to-severe postpartum depression. Postpartum depression may be diagnosed in women experiencing depressive symptoms which can manifest as cognitive, behavioral, or emotional disturbances as early as the third trimester to 4 weeks following delivery. The efficacy of brexanolone suggests that neurosteroids such as allopregnanolone are important to treat PPD. Read More

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Effects of March of Dimes Supportive Pregnancy Care on Social Support and Postpartum Depression.

Health Educ Behav 2021 Jun 6:10901981211019919. Epub 2021 Jun 6.

Vanderbilt University, Nashville, TN, USA.

Purpose: Group prenatal care, which integrates medical care with patient education and empowerment in a group setting, has the potential to build social support among pregnant women and reduce the risk of postpartum depression (PPD). Past research on group care's effects on social support or PPD has produced inconsistent findings. Studies have tended to (1) examine direct effects on social support or PPD and (2) treat group care participation as a dichotomous variable. Read More

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Exploring the convergence of knowledge, attitudes, and practice towards mental illness among nurses in South India: A cross-sectional analysis.

Asian J Psychiatr 2021 May 14;62:102696. Epub 2021 May 14.

KLE University Kaher Institute for Nursing Sciences, JN Medical College Campus, Nehru Nagar, Belagavi 590010, Karnataka, India.

Mental illness is a leading cause of global morbidity. Over 10% of the Indian population experience a mental health disorder yet deficits in knowledge and negative attitudes towards metal illness limit early identification and treatment. We explored the relationship among knowledge, attitudes and practice among generalist nurses working at a large tertiary care hospital in South India. Read More

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Destined for Greatness: A Family-Based Stress Management Intervention for African-American Mothers and their Children.

Soc Sci Med 2021 May 21;280:114058. Epub 2021 May 21.

Long Beach Department of Health & Human Services, Black Infant Health Program, 3820 Cherry Ave, Long Beach, CA, 90807, USA.

Rationale: African-American mothers in the U.S. experience high rates of stress, placing them at risk for depression, anxiety, and preterm births, and their children at risk for poor social-emotional development later in childhood. Read More

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Intrapartum synthetic oxytocin, behavioral and emotional problems in children, and the role of postnatal depressive symptoms, postnatal anxiety and mother-to-infant bonding: A Dutch prospective cohort study.

Midwifery 2021 May 20;100:103045. Epub 2021 May 20.

University of Groningen, University Medical Centre Groningen, Department of General Practice and Elderly Care Medicine, the Netherlands.

Objective: To examine the association between intrapartum synthetic oxytocin and child behavioral and emotional problems and to assess if maternal depressive or anxious symptoms or mother-to-infant bonding play a mediating role in this association.

Design: Prospective cohort study.

Setting: Population-based Pregnancy Anxiety and Depression Study. Read More

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Effectiveness of Moderate-Intensity Aerobic Water Exercise during Pregnancy on Quality of Life and Postpartum Depression: A Multi-Center, Randomized Controlled Trial.

J Clin Med 2021 May 30;10(11). Epub 2021 May 30.

Primary Care Research Unit of Mallorca, Balearic Islands Health Services, 07002 Palma, Spain.

Background: The global prevalence of postpartum depression is about 20%. This disease has serious consequences for women, their infants, and their families. The aim of this randomized clinical trial was to analyze the effectiveness and safety of a moderate-intensity aerobic water exercise program on postpartum depression, sleep problems, and quality of life in women at one month after delivery. Read More

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Caring for Mothers: A Narrative Review on Interpersonal Violence and Peripartum Mental Health.

Int J Environ Res Public Health 2021 May 16;18(10). Epub 2021 May 16.

Department of Psychiatry, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.

Interpersonal violence in the perinatal period is frequent and should be considered a prominent health issue due to the risk of escalation of violence and the significant impact on mothers' parenting after childbirth. Domestic violence during pregnancy can be associated with fatal and non-fatal adverse health outcomes due to the direct trauma to a pregnant woman's body and to the effect of stress on fetal growth and development. Emotional violence is a risk factor for prenatal and/or postpartum depression. Read More

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Effectiveness of psychological interventions in the treatment of perinatal depression: A systematic review of systematic reviews and meta-analyses.

J Affect Disord 2021 May 13;291:294-306. Epub 2021 May 13.

Department of Psychiatry, Eginition Hospital, University of Athens, Greece.

Background: Perinatal depression is a high prevalent mental health problem with serious consequences. Evidence about effective psychological interventions in treating perinatal depression has been increasing, but it lacks a comprehensive synthesis of findings.

Methods: A systematic review of systematic reviews and meta-analyses concerning the effectiveness of psychological interventions in treating perinatal depression (depression during pregnancy and the first 12 months postpartum) in adult women was conducted. Read More

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Is peripartum magnesium sulfate associated with a reduction in postpartum depressive symptoms?

Am J Obstet Gynecol MFM 2021 May 28:100407. Epub 2021 May 28.

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Background: The prevention of postpartum depression is an important area of investigation given its association with major maternal and neonatal sequelae, yet few evidence-based treatments to reduce the frequency of postpartum depression are utilized. Recent data suggest that N-methyl-D-aspartate receptor antagonists may lead to rapid improvement of depressive symptoms lasting up to 2 weeks. We hypothesized that the N-methyl-D-aspartate receptor antagonist magnesium sulfate would elicit antidepressant effects subsequent to its receipt by women receiving peripartum seizure prophylaxis for a hypertensive disorder of pregnancy. Read More

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Quantifying the incidence of clinically significant respiratory depression in women with and without obesity class III receiving neuraxial morphine for post-cesarean analgesia: a retrospective cohort study.

Int J Obstet Anesth 2021 May 7:103187. Epub 2021 May 7.

Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA.

Background: Obesity is a suspected risk factor for respiratory depression following neuraxial morphine for post-cesarean analgesia, however monitoring guidelines for obese obstetric patients are based on small, limited studies. We tested the hypothesis that clinically significant respiratory depression following neuraxial morphine occurs more commonly in women with body mass index (BMI) ≥40 kg/m compared with BMI <40 kg/m.

Methods: We conducted a single-center, retrospective chart review (2006-2017) of obstetric patients with clinically significant respiratory depression following neuraxial morphine, defined as: (1) opioid antagonist administration; (2) rapid response team activation (initiated in April 2010); or (3) tracheal intubation due to a respiratory event. Read More

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The prevalence and determinants of postpartum depression (PPD) symptomatology among facility delivered mothers of Dhaka city.

Asian J Psychiatr 2021 May 19;62:102673. Epub 2021 May 19.

Department of Public Heath, North South University, Dhaka, Bangladesh. Electronic address:

Background: Postpartum depression (PPD) is among the top mental health issues and affects children's health and cognitive development. This study aimed to identify the prevalence of PPD symptomatology and possible determinants among facility delivered mothers of Dhaka city.

Method: A cross-sectional study was conducted among 291 mothers within the 12 months of postpartum during January to May 2019. Read More

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Postpartum corticosterone and fluoxetine shift the tryptophan-kynurenine pathway in dams.

Psychoneuroendocrinology 2021 May 18;130:105273. Epub 2021 May 18.

Graduate Program in Neuroscience, University of British Columbia, Canada; Department of Psychology, University of British Columbia, Canada; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Canada. Electronic address:

Perinatal depression (PND) affects 15% of mothers. Selective serotonin reuptake inhibitors (SSRIs) are currently the first-line of treatment for PND but are not always efficacious. Previously, we found significant reductions in plasma tryptophan concentrations and higher hippocampal proinflammatory cytokine, IL-1β levels, due to maternal SSRI treatment. Read More

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