51 results match your criteria Postoperative Spindle Cell Nodule


Alveolar adenoma with poor imaging: a case report.

J Int Med Res 2020 Mar 10;48(3):300060519885269. Epub 2019 Nov 10.

Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.

Alveolar adenoma is an isolated, well-defined peripheral lung tumor that originates from type II alveolar cells. The tumor consists of a network of simple, low-cubic, epithelium-coated lacunae with varying amounts of fine and inconspicuous-to-thick spindle cells that sometimes contain mucus sample matrix. Few cases of alveolar adenoma have been reported. Read More

View Article and Full-Text PDF

A rare case of bipartite combined tumour of the oesophagus.

World J Surg Oncol 2019 May 6;17(1):79. Epub 2019 May 6.

Department of General Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, Singapore.

Background: Bipartite combined oesophageal tumours are an exceedingly rare entity and much less is known about the natural history of these tumours following curative surgery. The authors present a case of a bipartite combined oesophageal tumour comprising of sarcomatoid carcinoma and small cell carcinoma with early postoperative recurrence.

Case Presentation: A 63-year-old Chinese male with a smoking history presents with hemoptysis on a background of dysphagia and odynophagia for 1 month. Read More

View Article and Full-Text PDF

Primary pulmonary meningioma: A case report.

Medicine (Baltimore) 2017 May;96(19):e6474

Department of Cardiothoracic Surgery Department of Pathology, Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou, China.

Rationale: Primary extracranial meningiomas are rare outside the head and neck region.

Patient Concerns: A 44-year-old female patient had chest pain for more than 1 year.

Diagnoses: Preoperative chest computed tomography (CT) scan revealed a nodule in the right lower lobe, 1. Read More

View Article and Full-Text PDF

Incidentally Found Postoperative Spindle Cell Nodule of the Breast 6 Months After Ultrasound-Guided Vacuum-Assisted Excision.

Ultrasound Q 2017 Mar;33(1):55-57

*Department of Medicine, Graduate School, Kyung Hee University, and †Department of Radiology, Kyung Hee University Hospital, College of Medicine, Kyung Hee University, Seoul, South Korea.

Postoperative spindle cell nodule (PSCN) is a very rare pathologic complication that can occur in association with a recent core needle biopsy, surgery, or trauma. Cases of PSCN have been reported in the lower genitourinary tract, endometrium, and thyroid but are rare in the breast. Herein, we report an ultrasound-guided biopsy-proven PSCN after ultrasound-guided vacuum-assisted excision in the breast. Read More

View Article and Full-Text PDF

Inflammatory pseudotumor of the urinary bladder: A case series among more than 2,000 urinary bladder tumor cases.

Urol Ann 2016 Jan-Mar;8(1):95-8

Department of Urology, Urology and Nephrology Center, Mansoura University, Egypt.

"Inflammatory pseudotumor" (IPT) has infrequently been reported in the medical journals. A retrospective analysis was conducted among more than 2,000 bladder tumor cases from January 1999 to December 2012 looking for patients with IPT in the final diagnosis. Six patients were found with median tumor size of 3. Read More

View Article and Full-Text PDF
February 2016

Cutaneous metastasis from anaplastic thyroid carcinoma exhibiting exclusively a spindle cell morphology. A case report and review of literature.

J Cutan Pathol 2016 Mar 12;43(3):252-7. Epub 2015 Oct 12.

Department of Pathology, Section of Dermatopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Anaplastic thyroid carcinoma is a highly aggressive cancer accounting for 1-2% of thyroid malignancies. Cutaneous metastases from anaplastic thyroid carcinoma are exceedingly rare. We report a 65-year-old woman with anaplastic thyroid carcinoma (BRAF V600E mutation) who had lymph node metastases (pT4 N1b) treated by total thyroidectomy, postoperative radiotherapy, adjuvant chemotherapy (paclitaxel and pazopanib) and targeted therapy (vemurafenib). Read More

View Article and Full-Text PDF

Inflammatory myofibroblastic tumour of the urinary bladder: the role of immunoglobulin G4 and the comparison of two immunohistochemical antibodies and fluorescence in-situ hybridization for the detection of anaplastic lymphoma kinase alterations.

Histopathology 2015 Jul 29;67(1):20-38. Epub 2015 Jan 29.

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

Aims: We examined gene rearrangement and the expression of anaplastic lymphoma kinase (ALK) in urinary bladder inflammatory myofibroblastic tumour (IMT) using fluorescence in-situ hybridization (FISH) and two immunohistochemical antibodies to ALK. We also investigated whether IMT represents an immunoglobulin (Ig)G4-related disease.

Methods And Results: The performance of the Dako FLEX ALK monoclonal antibody (CD246) and the Cell Signaling Technology ALK (D5F3) XP monoclonal antibody were compared. Read More

View Article and Full-Text PDF

Primary pulmonary synovial sarcoma requiring differentiation from pulmonary metastasis of tibial adamantinoma: a case report.

BMC Res Notes 2014 Oct 18;7:736. Epub 2014 Oct 18.

Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.

Background: Primary pulmonary synovial sarcoma (PPSS) is rare. We describe a case of PPSS complicated by tibial adamantinoma that required differentiation from lung metastasis.

Case Presentation: A 39-year-old Japanese woman presented with hemoptysis, dyspnea, and a well-defined tumor measuring 3. Read More

View Article and Full-Text PDF
October 2014

Inflammatory myofibroblastic tumor of the bladder.

Arch Pathol Lab Med 2014 Oct;138(10):1272-7

From the Department of Pathology, University of Michigan Medical School, Ann Arbor.

We illustrate a case of an inflammatory myofibroblastic tumor (IMT) involving the bladder in a woman with dysuria and review the literature and differential diagnosis. Inflammatory myofibroblastic tumor, also referred to as pseudosarcomatous myofibroblastic proliferation, is a rare lesion that can arise in the genitourinary system and is characterized by a fascicular arrangement of myofibroblasts with admixed inflammatory cells and slitlike vessels. Urinary bladder IMT can be a diagnostic pitfall because its histologic features (brisk mitoses, invasion into muscularis propria, and prominent nucleoli) can mimic malignancy. Read More

View Article and Full-Text PDF
October 2014

Postoperative spindle cell nodule of the bladder: A case report and review of the literature.

Oncol Lett 2014 May 28;7(5):1507-1510. Epub 2014 Feb 28.

Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China.

Postoperative spindle cell nodule (PSCN) of the bladder is a rare condition. It is a type of benign lesion frequently misdiagnosed as sarcomatoid carcinoma on the basis of similar cell morphology. The present report describes a tumor affecting a 71-year-old male who had undergone three transurethral resections. Read More

View Article and Full-Text PDF

Giant cell angiofibroma of the scalp: A benign rare neoplasm with bone destruction.

Surg Neurol Int 2013 30;4:131. Epub 2013 Sep 30.

Department of Neurosurgery, Universitas Padjadjaran-Dr. Hasan Sadikin General Hospital, Bandung, Indonesia ; Oncology Working Group, Health Research Unit, Universitas Padjadjaran-Dr. Hasan Sadikin General Hospital, Bandung, Indonesia.

Background: The incidence of extraorbital giant cell angiofibroma (GCA) is rare, with only one case located in the scalp reported in the literature. The morphological hallmark is histopathological examination showing richly vascularized pattern-less spindle cell proliferation containing pseudovascular spaces and floret-like multinucleate giant cells.

Case Description: We report a case of a 30-year-old female with a primary complaint of a painless solitary nodule arising on the left parietal region of the scalp. Read More

View Article and Full-Text PDF
November 2013

Mixed endometrial stromal and smooth muscle tumor: report of a case with focal anaplasia and early postoperative lung metastasis.

Pathol Int 2013 Apr;63(4):214-9

Department of Pathology, Osaka Red Cross Hospital, Osaka 543-8555, Japan.

A rare case of a mixed endometrial stromal and smooth muscle tumor arising in the uterus of a 74-year-old woman is reported. The patient underwent hysterectomy for an enlarging uterine mass, and a large intramural tumor, showing marked central hyaline necrosis with calcification, was found. The tumor consisted of an admixture of a low-grade endometrial stromal sarcoma (ESS) and a fascicular proliferation of spindle cells suggesting smooth muscle differentiation, and a characteristic 'star-burst' appearance was found. Read More

View Article and Full-Text PDF

Fine needle aspiration cytology of postoperative spindle cell nodule in neck after thyroidectomy: a case report.

Korean J Pathol 2013 Feb 25;47(1):89-91. Epub 2013 Feb 25.

Department of Pathology, Gachon University School of Medicine, Gachon University Gil Medical Center, Incheon, Korea.

View Article and Full-Text PDF
February 2013

High-grade myxofibrosarcoma presenting at the spermatic cord after radiotherapy for prostate cancer.

BMJ Case Rep 2012 Nov 28;2012. Epub 2012 Nov 28.

Department of Urology, Terada Clinic, Hamamatsu, Shizuoka, Japan.

A 72-year-old man with a history of prostate cancer presented 7 years postradiotherapy with a painless, egg-sized, rapidly growing nodule on the left groin at the radiation site. He underwent left high orchiectomy under a diagnosis of groin lymph node metastasis of prostate cancer. The tumour had penetrated deep into the internal inguinal ring and was resected as proximally as possible to the internal ring with a positive surgical margin. Read More

View Article and Full-Text PDF
November 2012

Nodule on the scrotum.

Skinmed 2011 Sep-Oct;9(5):323-5

Department of Dermatology, Venereology & Leprology, Gian Sagar Medical College & Hospital, Ram Nagar, Banur, Patiala, India.

A 39-year-old Sikh businessman of Asian origin was referred to us with complaints of a painless scrotal lesion that had enlarged over a 2-year period and was causing him discomfort. There was no history of trauma, inflammation, or infection, and no significant urologic history. Physical examination revealed a 2x2 cm skin-colored nodule of rubbery consistency on the left side of the scrotum (Figure 1), which was separate from the testicles or epididymis. Read More

View Article and Full-Text PDF
December 2011

Postoperative spindle cell nodule after thyroidectomy: a case mimicking recurrence with anaplastic transformation of thyroid cancer.

Head Neck 2013 Jan 22;35(1):E13-7. Epub 2011 Nov 22.

Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: Here, we report a case of a postoperative spindle cell nodule that mimicked recurrence with anaplastic transformation after thyroidectomy.

Methods: The course of the disease is described. The mass was studied morphologically and immunohistochemically. Read More

View Article and Full-Text PDF
January 2013

[Resected pleomorphic carcinoma after long-time follow-up].

Kyobu Geka 2010 Jul;63(7):542-5

Department of Cardiothoracic Surgery, The University of Tokyo, Graduate School of Medicine, Tokyo, Japan.

We report a case of surgical resection of a pulmonary pleomorphic carcinoma after 6 years follow-up. A 75-year-old male patient was referred to our department for an irregular shadow (32 x 17 mm) in the left upper lung lobe. Chest computed tomography (CT) conducted 6 years before showed an 8 x 5 mm nodule in the same location; after 3 years prior the nodule had a thin wall cavity, and 2 years ago a new nodule was observed within the cavity. Read More

View Article and Full-Text PDF

[Pseudosarcomatous myofibroblastic proliferation of the bladder].

Prog Urol 2010 Apr 21;20(4):307-10. Epub 2009 Jun 21.

Service d'anatomie et de cytologie pathologiques, hôpital Fattouma-Bourguiba, rue du 1(er) juin 1955, 5000 Monastir, Tunisie.

Myofibroblastic proliferations of the bladder in adults are unusual lesions with a benign course. These proliferations, whether spontaneous or secondary to instrumentation, have identical morphology and behaviour. Histologically, similar lesions have been reported in the literature using different names, such as inflammatory pseudotumour, pseudosarcomatous fibromyxoid tumour, nodular fasciitis, postoperative spindle cell nodule. Read More

View Article and Full-Text PDF

Iris melanoma arising from sector congenital ocular melanocytosis in a child.

Cornea 2009 Dec;28(10):1191-3

Pathology Department, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA, USA.

Purpose: To report a clinicopathologic correlation of a melanoma arising from iris component of ocular melanocytosis in a child.

Methods: A 13-year-old boy developed a progressive iris nodule arising from sector iris pigmentation that was a component of congenital ocular melanocytosis involving the iris, ciliary body and choroid. The tumor was examined clinically and with ultrasound biomicroscopy (UBM), removed by peripheral iridocyclectomy, and studied histopathologically. Read More

View Article and Full-Text PDF
December 2009

Tumor-like lesions of the urinary bladder.

Authors:
Robert H Young

Mod Pathol 2009 Jun;22 Suppl 2:S37-52

The James Homer Wright Pathology Laboratories, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Warren Building, Fruit Street, Boston, MA 2114, USA.

Tumor-like lesions of the urinary bladder are reviewed emphasizing those that are most diagnostically challenging for the pathologist and may result in serious errors in patient care if misinterpreted. The first category considered, pseudocarcinomatous proliferations, represents an area of bladder pathology only recently appreciated as being particularly treacherous because of the extent to which irregular islands of benign epithelial cells may seemingly penetrate the lamina propria and cause confusion with carcinoma. Somewhat orderly proliferations of this type have been known for years, von Brunn's nests, and are rarely a challenge for the experienced, but proliferations of an irregular nature such as may be seen most often as a result of prior radiation therapy, but sometimes due to chemotherapy or even ischemia, represent a challenging interpretation. Read More

View Article and Full-Text PDF

Extragastrointestinal stromal tumor and liver transplantation: case report and review.

Transplant Proc 2008 Dec;40(10):3781-3

Unit of Liver Transplantation, State University of Campinas, Campinas, Sao Paulo, Brazil.

The occurrence of de novo malignant neoplasias has been shown in postransplant patients under imunosuppression. It is the second leading cause of late death in liver transplant recipients. The greatest incidence is seen in cancers associated with chronic infection by human papilloma virus, skin cancers, oropharyngeal, and gastrointestinal (GI) malignancies. Read More

View Article and Full-Text PDF
December 2008

Postoperative spindle cell nodule of the breast: Pseudosarcomatous myofibroblastic proliferation following endo-surgery.

Pathol Int 2008 Dec;58(12):787-91

Department of Anatomical Pathology, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain.

Despite the frequent use of fine-needle aspiration, core biopsy and surgery, postoperative spindle cell nodule (PSCN) is a rare pathological complication that may be diagnostically treacherous. Presented herein is the case of a 52-year-old woman who developed a 7 mm mammary nodular lesion 66 days after removal of an area of columnar cell hyperplasia involving cellular and architectural atypia, performed with the Mammotome Breast Biopsy System. The lesion was highly cellular and composed of intersecting fascicles of plump spindle cells with blunt-ended elongated nuclei and nucleoli easily visible. Read More

View Article and Full-Text PDF
December 2008

Metastatic monophasic synovial sarcoma of the pleura.

Ann Thorac Cardiovasc Surg 2007 Aug;13(4):258-61

Department of Thoracic Surgery, Osaka City University Hospital, Osaka, Japan.

Pleural metastasis of synovial sarcoma that originally developed in the soft tissue is a very rare entity. We report here the detailed clinical features of such a case. An asymptomatic 25-year-old female, with a history of a resected synovial sarcoma in her left brachial muscle and pulmonary metastasectomy of the right lung, presented a small nodule in the periphery of the left lung on a routine chest-computed tomography. Read More

View Article and Full-Text PDF

Soft tissue tumors of the urinary bladder, Part I: myofibroblastic proliferations, benign neoplasms, and tumors of uncertain malignant potential.

Hum Pathol 2007 Jun;38(6):807-23

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

Most bladder tumors arise from the urothelium. However, there are several uncommon but significant bladder lesions that must be differentiated from urothelial carcinomas. These include both benign and malignant spindle cell lesions. Read More

View Article and Full-Text PDF

Solid pancreatic hamartoma.

Pathol Int 2007 May;57(5):276-80

Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

A case of solid pancreatic hamartoma in a 58-year-old Japanese woman is presented. She had no symptoms, and a pancreatic mass was incidentally found on screening ultrasonography 4 months before admission. The patient was not alcoholic and had no history of pancreatitis. Read More

View Article and Full-Text PDF

Trisomy 7 in postoperative spindle cell nodules.

Cancer Genet Cytogenet 2007 Apr;174(2):147-50

Department of Medical Genetics, Rikshospitalet-Radiumhospitalet Medical Centre, Ullernchaussen 70, 0310 Oslo, Norway.

Postoperative spindle cell nodule is a localized, non-neoplastic, reparative lesion composed of closely packed proliferating spindle cells and capillaries simulating a leiomyosarcoma. The lesion typically develops at the site of a recent surgical wound several weeks to months postoperatively. Local recurrence of postoperative spindle cell nodules has not been reported, even after incomplete resection. Read More

View Article and Full-Text PDF

Cutaneous leiomyosarcoma, trichoblastoma, and syringocystadenoma papilliferum arising from nevus sebaceus.

Int J Dermatol 2007 Mar;46(3):306-8

Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, India.

A 54-year-old man presented with a recurrent swelling on the right occipital region of the scalp. Two months earlier, the patient had undergone an initial local excision of the lesion which had enlarged progressively over the previous 2 years on a hairless patch which had been present since birth. On examination, a 5 x 4-cm, pinkish, firm, ulcerated swelling was seen on the right occipital region with a scar running over it. Read More

View Article and Full-Text PDF

Pseudosarcomatous and sarcomatous proliferations of the bladder.

Hum Pathol 2007 May 15;38(5):753-61. Epub 2007 Feb 15.

Department of Urologic Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

Pseudosarcomatous fibromyxoid tumor (PFT), postoperative spindle cell nodule (PSN), sarcoma, and sarcomatoid carcinoma of the bladder are frequently difficult to distinguish histopathologically with significant differences in disease-related outcomes. A retrospective review of our pathology registry over the last 25 years identified 7 PFT, 10 PSN, 18 primary bladder sarcomas, and 17 sarcomatoid carcinomas. Most patients with PFT, PSN, sarcoma, and sarcomatoid carcinoma were diagnosed between the ages of 50 to 60 years with PFT and PSN most commonly detected in women. Read More

View Article and Full-Text PDF

Inflammatory myofibroblastic tumors of the urinary tract: a clinicopathologic study of 46 cases, including a malignant example inflammatory fibrosarcoma and a subset associated with high-grade urothelial carcinoma.

Am J Surg Pathol 2006 Dec;30(12):1502-12

Department of Pathology, Johns Hopkins Hospital, Baltimore, MD 21231, USA.

Inflammatory myofibroblastic tumor (IMT) of the urinary tract, also termed postoperative spindle cell nodule, inflammatory pseudotumor, and pseudosarcomatous fibromyxoid tumor, is rare and in the past was believed to reflect diverse entities. We reviewed a series of 46 IMTs arising in the ureter, bladder, and prostate, derived primarily from a large consultation practice. There were 30 male and 16 females aged 3 to 89 years (mean 53. Read More

View Article and Full-Text PDF
December 2006

[Cavitating pleomorphic carcinoma of the lung; report of a case].

Kyobu Geka 2006 Sep;59(10):959-61

Department of Thoracic Surgery, Haibara General Hospital, Makinohara, Japan.

We report a case of a previously healthy 76-year-old male with cavitating pleomorphic carcinoma of the lung. He was admitted because of an abnormal lung shadow on chest X-ray. Computed tomography (CT) showed a well-demarcated nodular shadow within thin-walled cavity in the right upper lobe. Read More

View Article and Full-Text PDF
September 2006