970 results match your criteria Postinflammatory Hyperpigmentation


Aesthetic considerations in female skin of color: what you need to know.

Semin Cutan Med Surg 2018 Dec;37(4):210-216

Department of Dermatology, Weill Cornell Medical College, New York, New York, USA.

The world is flat when it comes to aesthetic treatments, meaning women and men from all walks of life, regardless of culture and ethnicity or even socioeconomic status, are seeking ways to improve their appearance, prevent aging, and rejuvenate their skin. Year after year, statistics show a steady increase in people of color undergoing aesthetic treatments, with neurotoxins, fillers, laser resurfacing, and body contouring being the most sought-after procedures. When treating this cohort of patients, however, dermatologists need to be sensitized to how a patient's ethnicity affects facial structure, the tissue reaction to treatments, and patient's specific expectations for recommended therapies. Read More

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December 2018
3 Reads

Inflammation of the Temporal Bone.

Neuroimaging Clin N Am 2019 Feb 29;29(1):1-17. Epub 2018 Oct 29.

Department of Radiology, University Hospitals of Leicester, Leicester University, Infirmary Square, Leicester LE1 5WW, UK.

Temporal bone and ear structure inflammation is commonly due to infection. It can be associated with a variety of complications and postinflammatory sequelae. Where the ear is easily inspected, clinical evaluation suffices. Read More

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February 2019
5 Reads

Hyperpigmented Upper Eyelid: A Clue to the Diagnosis of Facial Lichen Planus Pigmentosus in a Patient with Frontal Fibrosing Alopecia.

Skin Appendage Disord 2018 Oct 4;4(4):335-338. Epub 2018 Apr 4.

Universidade Federal Fluminense, Niterói, Brazil.

Facial lichen planus pigmentosus (LPPig), a rare variant of classic lichen planus, was first described in patients with frontal fibrosing alopecia (FFA) by Dlova [Br J Dermatol 2013; 168: 439-442] in 2013. The diagnosis of facial LPPig is sometimes not easy, since clinical signs and histopathological features may frequently be confused with melasma or postinflammatory hyperpigmentation. We describe a case of a postmenopausal black woman diagnosed with FFA who presented with an identical brown-grayish pigmentation of the face and upper eyelids and typical dermoscopy analysis on both regions. Read More

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October 2018
6 Reads

The Spectrum and Sequelae of Acne in Black South Africans Seen in Tertiary Institutions.

Skin Appendage Disord 2018 Oct 30;4(4):301-303. Epub 2018 May 30.

School of Public Health and Nursing, University of KwaZulu-Natal, Durban, South Africa.

Introduction: Acne is a chronic disorder of the pilosebaceous unit affecting all ethnic groups. It remains in the top 5 skin conditions seen worldwide. The paucity of data characterizing acne in South African Blacks led us to the documentation of types and sequelae of acne. Read More

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October 2018
4 Reads

Assessment of quality of life in patients of urethral stricture on clean intermittent catheterization following direct vision internal urethrotomy.

Urol Ann 2018 Oct-Dec;10(4):395-399

Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Context: Clean intermittent catheterization (CIC) after direct vision internal urethrotomy (DVIU).

Aims: The aim is to assess the quality of life (QOL) in patients with urethral strictures on CIC following DVIU.

Settings And Design: Prospective study. Read More

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November 2018
3 Reads

A randomized study to evaluate the efficacy and effectiveness of two sunscreen formulations on Indian skin types IV and V with pigmentation irregularities.

Indian J Dermatol Venereol Leprol 2018 Oct 29. Epub 2018 Oct 29.

L'Oréal Research and Innovation Campus, Clichy, France.

Background: Regular exposure to ultraviolet rays is high in India, where most Indians present Fitzpatrick skin phototypes IV and V.

Aims: To evaluate the efficacy and compare the effectiveness of two sunscreen products on Indian skin types IV and V with pigmentation irregularities.

Methods: A randomized, uncontrolled and investigator-blinded, single-center study enrolled adult men and women (18-45 years) with Fitzpatrick skin phototypes IV (28° < individual typological angle <10°) and V (10° < individual typological angle < -30°) with pigmentary abnormalities seen on the face in adults (actinic lentigines and postinflammatory hyperpigmentation), who did not use sunscreens. Read More

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October 2018
3 Reads
1.320 Impact Factor

Managing Periocular Filler-Related Syndrome Prior to Lower Blepharoplasty.

Aesthetic Plast Surg 2018 Oct 8. Epub 2018 Oct 8.

Keck School of Medicine, University of Southern California, 9401 Wilshire Blvd, Suite 1105, Beverly Hills, CA, 90212, USA.

Background: Hyaluronic acid (HA) fillers are extensively used in periocular volume augmentation. Although they have an excellent safety profile, filler-related issues such as visibility/palpability, contour abnormalities, malar edema, and blue-gray dyschromia can occur. Recognition and management of filler-related issues are critical prior to subsequent procedures. Read More

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October 2018
9 Reads

Topical brimonidine-assisted laser treatment for the prevention of therapy-related erythema and hyperpigmentation.

J Cosmet Laser Ther 2018 Sep 20:1-3. Epub 2018 Sep 20.

c Department of Dermatology , Chung-Ang University College of Medicine , Seoul , Korea.

Postinflammatory hyperpigmentation (PIH) and erythema are the most common adverse effects associated with laser treatment, particularly in dark-skinned individuals. Several methods have been used to prevent or minimize these adverse effects; however, to date, no definitive precautions/strategies are known to prevent post-laser PIH and erythema. We investigated whether the topical application of the α-adrenergic receptor agonist brimonidine could reduce laser treatment-related complications such as erythema and PIH. Read More

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September 2018
1 Read

Noninvasive Atrophic Acne Scar Treatment in Asians With a 755-nm Picosecond Laser Using A Diffractive Optic Lens-A Retrospective Photographic Review.

Dermatol Surg 2018 Sep 18. Epub 2018 Sep 18.

P-Skin Professional Clinic, Kaohsiung, Taiwan, China.

Background: The diffractive lens of the picosecond laser is relatively new, and there are few reports on its efficacy in treating atrophic acne scars, especially in Asian populations.

Objective: Evaluating the efficacy of diffractive lens 755-nm picosecond laser for atrophic acne scar treatment in Asians.

Patients And Methods: Forty-two patients who were treated for facial atrophic acne scars at a private dermatological clinic were enrolled in this retrospective analysis. Read More

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September 2018
1 Read

[Surgical management of strabismus in dysthyroid orbitopathy: A retrospective single-center study of 32 cases].

J Fr Ophtalmol 2018 Oct 11;41(8):687-695. Epub 2018 Sep 11.

Service d'ophtalmologie, CHRU Bretonneau, 2, boulevard Tonnelé, 37044 Tours cedex 9, France.

Introduction: Thyroid-related immune orbitopathy often results in a restrictive strabismus. We report our experience of surgical management in these cases.

Patients And Methods: We present a retrospective case series conducted on 32 patients, operated between 2008 and 2017. Read More

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October 2018
9 Reads

Treating Acne in Patients With Skin of Color.

Semin Cutan Med Surg 2018 Jun;37(3S):S71-S73

Adjunct Professor Schulich School of Medicine and Dentistry Western University Windsor, Ontario, Canada.

Patients with skin of color are more likely to develop acne and postinflammatory hyperpigmentation (PIH). Many therapies for acne have demonstrated efficacy in darker skin types and in the treatment of PIH. Semin Cutan Med Surg 37(supp3):S71-S73 © 2018 published by Frontline Medical Communications. Read More

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Bullous sweet syndrome healing with prominent secondary anetoderma.

Pediatr Dermatol 2018 Nov 28;35(6):e416-e417. Epub 2018 Aug 28.

Department of Dermatology, SUNY Downstate Medical Center, Brooklyn, New York.

A 15-month-old boy presented with 1-4 cm, pink edematous plaques with overlying round erosions and hemorrhagic bullae in the setting of a gastrointestinal illness and was ultimately diagnosed with bullous-type Sweet syndrome. Despite appropriate treatment with oral steroids, the patient's cutaneous lesions healed with secondary anetoderma. This case should prompt practitioners to be aware of bullous-type Sweet syndrome and the possibility of lesions healing with postinflammatory scarring. Read More

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November 2018
6 Reads

The role of systemic treatments for skin lightening.

J Cosmet Dermatol 2018 Dec 21;17(6):1144-1157. Epub 2018 Aug 21.

The Ronald O. Perelman Department of Dermatology, New York University Langone Health, New York City, New York.

Background: Pigmentation of the skin occurs as a result of increased melanin production or deposition due to various reasons including age, hormonal imbalances, endocrine disease, inflammation, and/or exposure to damaging radiation, resulting in dermatologic conditions such as lentigines, melasma, or postinflammatory hyperpigmentation. Although numerous topical therapies exist for skin lightening, they are limited by efficacy and pigmentation recurrence after treatment cessation. New research into systemic therapies for hyperpigmentation has been promising. Read More

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December 2018
18 Reads

Glucagonoma-Associated Necrolytic Migratory Erythema: The Broad Spectrum of the Clinical and Histopathological Findings and Clues to the Diagnosis.

Am J Dermatopathol 2018 Sep 17. Epub 2018 Sep 17.

Department of Dermatology, Venerology and Allergology, University Medical Center, Ruprecht-Karls-University Heidelberg, Heidelberg, Germany.

Necrolytic migratory erythema (NEM) is associated with glucagonoma, an endocrine malignancy of the pancreas. It is a rare and a likely underrecognized paraneoplastic dermatitis. A 38-year-old woman presented to our clinic with a 3-year history of reocurring pruritic skin rashes with increasing intensity. Read More

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September 2018
9 Reads

Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients.

Case Rep Dermatol Med 2018 9;2018:9406797. Epub 2018 Jul 9.

Department of Dermatology, Jordan University Hospital, Amman, Jordan.

Prurigo pigmentosa is a unique cutaneous inflammatory disorder characterized by a sudden onset of pruritic and erythematous macules, urticarial papules, and plaques that may coalesce to form a reticulated pattern. Lesions typically heal within weeks leaving a reticulated and mottled postinflammatory hyperpigmentation. The majority of reported cases originate from Japan with much fewer cases described worldwide without predominant ethnicity. Read More

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July 2018
10 Reads

Patterns of Over-the-counter Lightening Agent Use among Patients with Hyperpigmentation Disorders: A United States-based Cohort Study.

J Clin Aesthet Dermatol 2018 Jul 1;11(7):26-30. Epub 2018 Jul 1.

Drs. Saade, Maymone, and Vashi are with the Department of Dermatology at Boston University School of Medicine in Boston, Massachusetts.

Over-the-counter (OTC) lightening agents are commonly used to treat hyperpigmentation disorders. We sought to determine the characteristics, trends, and preferences of patients with hyperpigmentation disorders seeking OTC agents in the United States. The study was a cross-sectional study of consecutive patients with a disorder of hyperpigmentation seen in a United States-based outpatient dermatology clinic. Read More

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July 2018
1 Read

Characteristics and management of Asian skin.

Int J Dermatol 2018 Jul 24. Epub 2018 Jul 24.

Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil.

Color differences in skin are due to the amount and distribution of epidermal melanin. The number of melanocytes is almost the same in all skin types, but higher phototypes exhibit more melanocytes, which produce more melanin and melanosomes that are individually distributed throughout the keratinocyte layers. This characteristic ensures a natural, significant photoprotection in darker skins. Read More

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July 2018
9 Reads

Chemical peels in the treatment of acne: patient selection and perspectives.

Clin Cosmet Investig Dermatol 2018 16;11:365-372. Epub 2018 Jul 16.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA,

Acne vulgaris is the most common skin disorder in adolescents and young adults. It carries a significant psychological and economic burden to patients and society. A wide range of therapeutic options are available, including topicals and systemic therapies. Read More

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Brimonidine tartrate gel plus topical steroid for the prevention of laser therapy-related postinflammatory hyperpigmentation.

Dermatol Ther 2018 09 20;31(5):e12657. Epub 2018 Jul 20.

Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.

Brimonidine gel, originally approved for the treatment of facial rosacea, causes direct vasoconstriction and possesses extensive utilization in dermatologic fields. A Q-switched (QS) neodymium-doped yttrium aluminum garnet (Nd:YAG) laser is generally used to treat solar lentigo (SL), often leaving unwanted postinflammatory hyperpigmentation (PIH), especially in dark-skinned individuals. A 58-year-old man with Fitzpatrick skin type IV presented to remove solar lentigines from his face. Read More

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September 2018
3 Reads

The effects of recombinant human epidermal growth factor containing ointment on wound healing and post inflammatory hyperpigmentation prevention after fractional ablative skin resurfacing: A split-face randomized controlled study.

J Cosmet Dermatol 2018 Oct 29;17(5):756-761. Epub 2018 Jun 29.

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Epidermal growth factor (EGF) is one of the important peptides in wound healing process. The effects of EGF have been increasingly studied in various types of ulcers. However, data on postablative laser resurfacing wound is still limited. Read More

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October 2018
6 Reads

Q-switched double frequency Nd:YAG 532-nm nanosecond laser vs. double frequency Nd:YAG 532-nm picosecond laser for the treatment of solar lentigines in Asians.

Lasers Med Sci 2018 Dec 15;33(9):1941-1947. Epub 2018 Jun 15.

Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI road, Rajthevi, Bangkok, 10400, Thailand.

Solar lentigines are common pigmentary lesions. Q-switched lasers are effective treatment options but postinflammatory hyperpigmentation (PIH) is common in darker skin. The objective of the study is to compare the efficacy and safety in solar lentigines of Asian skin treated by Q-switched potassium titanyl phosphate (KTP) 532-nm nanosecond laser vs. Read More

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December 2018
4 Reads

Fever of unknown origin: a challenging case.

BMJ Case Rep 2018 Jun 4;2018. Epub 2018 Jun 4.

Infectious Diseases, Mater Dei Hospital, Msida, Malta.

We report a case of Cogan's syndrome presenting as fever of unknown origin in a 31-year-old woman who was admitted to the hospital with a 7-week history of fever, night sweats and other constitutional symptoms. The diagnosis remained elusive despite numerous investigations, and the patient subsequently developed rash, episcleritis, dizziness and sensorineural hearing loss. While initially thought to be a postinflammatory response to a previous infection, confirmation of the rash as a vasculitis together with the audiovestibular and ocular involvement led to a clinical diagnosis of Cogan's syndrome. Read More

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June 2018
1 Read

Case Report of a 21-Year-Old Man With Epidermolysis Bullosa Acquisita.

J Cutan Med Surg 2018 May/Jun;22(3):356-358

2 Division of Dermatology and Department of Laboratory Medicine & Pathobiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Epidermolysis bullosa acquisita (EBA) is a rare acquired type of mechanobullous disease affecting the dermal-epidermal junction (DEJ) of trauma prone acral surfaces. It manifests as tense vesicles, bullae, and milia and typically heals as atrophic hypo- or hyperpigmented scars. Classic noninflammatory mechanobullous EBA typically presents at a mean age of 48 years. Read More

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December 2018
1 Read

A Review of the Use of Ultrasound for Skin Tightening, Body Contouring, and Cellulite Reduction in Dermatology.

Dermatol Surg 2018 07;44(7):949-963

Both authors are affiliated with the Department of Dermatology, University of California, Irvine, Irvine, California.

Background: Ultrasound (US) technology uses acoustic waves to heat tissue, resulting in thermal damage and coagulative necrosis leading to the renewal of skin elasticity, body contouring, and destruction of cellulite.

Objective: This review will discuss the use of US for skin tightening, body contouring/sculpting, and cellulite reduction.

Materials And Methods: A literature search identified studies using US for skin tightening, body contouring/sculpting, and cellulite reduction. Read More

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July 2018
9 Reads

Local regulatory mechanism to coordinate colorectal motility in rats.

Physiol Rep 2018 May;6(10):e13710

Laboratory of Veterinary Physiology, Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan.

The presence of a fecal pellet in the colorectum causes ascending contraction and descending relaxation, propelling the pellet aborally. However, random occurrence of the reflexes at multiple sites would disturb sequential excretion of the pellets, resulting in inefficient defecation. Hence, we postulated that a regulatory mechanism to coordinate peristaltic motility initiated at adjacent portions of the colorectum may exist. Read More

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May 2018
1 Read

Cardiomyopathy, oxidative stress and impaired contractility in a rheumatoid arthritis mouse model.

Heart 2018 Dec 26;104(24):2026-2034. Epub 2018 May 26.

Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.

Objectives: Patients with rheumatoid arthritis (RA) display an increased risk of heart failure independent of traditional cardiovascular risk factors. To elucidate myocardial disease in RA, we have investigated molecular and cellular remodelling of the heart in an established mouse model of RA.

Methods: The collagen antibody-induced arthritis (CAIA) RA mouse model is characterised by joint inflammation and increased inflammatory markers in the serum. Read More

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December 2018
1 Read

Treatment of Facial Hypopigmented Scars by the Laser Hole Technique Using a Nonfractional Carbon Dioxide Laser in Asians.

Plast Reconstr Surg 2018 08;142(2):126e-132e

Seoul, Republic of Korea From the Department of Plastic Surgery, College of Medicine, Kyung Hee University.

Background: Facial hypopigmented scars are usually characterized by white color and a glossy surface. To correct the two problems simultaneously, the authors attempted to induce persistent postinflammatory hyperpigmentation for color and to build multiple pitted scars like facial skin pores for texture. This study describes a laser hole method using a traditional nonfractional carbon dioxide laser for treatment of facial hypopigmented scars and evaluates the clinical results. Read More

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August 2018
5 Reads

[Congenital megacalycosis in a girl with unilateral renal agenesis].

Pol Merkur Lekarski 2018 Apr;44(262):205-207

Medical University of Warsaw, Poland: Department of Pediatric Surgery and Urology.

Renal agenesis occurs in pediatric population with the incidence 1:500- 2000 children. It is more often diagnosed in boys and on the left side of the body. Renal agenesis may be isolated or it may be a part of complex malformation syndrome. Read More

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April 2018
3 Reads

Resurfacing of Facial Acne Scars With a New Variable-Pulsed Er:YAG Laser in Fitzpatrick Skin Types IV and V.

J Cutan Aesthet Surg 2018 Jan-Mar;11(1):20-25

Venkat Charmalaya-Centre for Advanced Dermatology and Postgraduate Training, 3437, 1st G Cross, 7 main, Subbanna Garden, Vijay Nagar, Bangalore, India.

Introduction: The Er:YAG laser, considered to be less effective than CO laser in its traditional form, in its new modulated version has variable pulse technology that is claimed to be superior to the earlier versions of the laser.

Aim: The aim of the study was to check efficacy and safety of the new variable square pulse (VSP) Er:YAG laser in the management of acne scar in patients with Fitzpatrick skin types IV and V.

Materials And Methods: This retrospective study consisted of 80 patients (Fitzpatrick skin types IV and V) with atrophic and hypertrophic facial acne scars. Read More

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May 2018
3 Reads

High-fluence 1064-nm Q-Switched Nd:YAG laser: Safe and effective treatment of café-au-lait macules in Asian patients.

J Cosmet Dermatol 2018 Jun 3;17(3):380-384. Epub 2018 May 3.

Choice Dermatology Clinic, Pyeongchon, Korea.

Objectives: Café-au-lait macules (CALMs) are benign cutaneous hyperpigmentary disorders. Usually, laser therapies for cosmetic concerns result in more severe side effects in the people of Asian descent than that of Caucasians. Unfortunately, there is no gold standard for the laser treatment of CALMs in skin of people of Asian descent. Read More

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June 2018
10 Reads

Consecutive negative findings on colonoscopy during surveillance predict a low risk of advanced neoplasia in patients with inflammatory bowel disease with long-standing colitis: results of a 15-year multicentre, multinational cohort study.

Gut 2018 May 2. Epub 2018 May 2.

Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands.

Objectives: Surveillance colonoscopy is thought to prevent colorectal cancer (CRC) in patients with long-standing colonic IBD, but data regarding the frequency of surveillance and the findings thereof are lacking. Our aim was to determine whether consecutive negative surveillance colonoscopies adequately predict low neoplastic risk.

Design: A multicentre, multinational database of patients with long-standing IBD colitis without high-risk features and undergoing regular CRC surveillance was constructed. Read More

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May 2018
8 Reads

Analgesic effects of electroacupuncture at ST25 and CV12 in a rat model of postinflammatory irritable bowel syndrome visceral pain.

Acupunct Med 2018 Aug 2;36(4):240-246. Epub 2018 May 2.

College of Public Hygiene, Shaanxi University of Chinese Medicine, Xi'an-Xianyang New Economic Zone, Shaanxi Province, China.

Background: Treatment with electroacupuncture (EA) at ST25 and CV12 has a significant analgesic effect on postinflammatory irritable bowel syndrome (PI-IBS) visceral pain. Enterochromaffin (EC) cells and serotonin (5-hydroxytryptamine (5-HT)) are important in the development of visceral hyperalgesia.

Objective: To investigate the analgesic effect and underlying mechanisms of EA at ST25 and CV12 on the treatment of trinitrobenzene sulfonic acid (TNBS)-induced PI-IBS visceral hyperalgesia in rats. Read More

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August 2018
2 Reads

Sesamol Inhibited Melanogenesis by Regulating Melanin-Related Signal Transduction in B16F10 Cells.

Int J Mol Sci 2018 Apr 7;19(4). Epub 2018 Apr 7.

Department of Cosmeceutics, China Medical University, Taichung 40402, Taiwan.

Melanin is synthesized through a series of interactions catalyzed by melanogenic enzymes such as tyrosinase, dopachrome tautomerase (tyrosinase-related protein-2; TRP-2), and tyrosinase-related protein-1 (TRP-1). Tyrosinase plays a key role in catalysing the initial and limiting steps of melanogenesis. The melanin that results from melanogenesis has the protective effect of absorbing ultraviolet radiation. Read More

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Assessing the safety of superficial chemical peels in darker skin: A retrospective study.

J Am Acad Dermatol 2018 Sep 5;79(3):508-513.e2. Epub 2018 Mar 5.

Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts. Electronic address:

Background: Chemical peels have shown efficacy in the treatment of acne, photoaging, and pigmentary dyschromias; however, studies evaluating side effects, particularly in patients with skin of color, are limited.

Objective: We sought to determine the frequency of side effects and complications associated with superficial chemical peels in patients with skin types III-VI.

Methods: A 5-year single center retrospective analysis was performed. Read More

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September 2018
12 Reads

Ablative fractional carbon dioxide laser combined with intense pulsed light for the treatment of photoaging skin in Chinese population: A split-face study.

Medicine (Baltimore) 2018 Jan;97(3):e9494

Intense pulsed light (IPL) is effective for the treatment of lentigines, telangiectasia, and generalized erythema, but is less effective in the removal of skin wrinkles. Fractional laser is effective on skin wrinkles and textural irregularities, but can induce postinflammatory hyperpigmentation (PIH), especially in Asians. This study evaluated the safety and efficacy of ablative fractional laser (AFL) in combination with IPL in the treatment of photoaging skin in Asians. Read More

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January 2018
3 Reads

[Bullosis diabeticorum : Two case studies].

Hautarzt 2018 Sep;69(9):751-755

Klinik für Dermatologie, Allergologie und Phlebologie, Klinikum Bremerhaven Reinkenheide, Postbrookstr. 103, 27574, Bremerhaven, Deutschland.

We report two cases of patients with diabetes mellitus who developed bullae measuring 2 cm in diameter on the fingers or toes, which could be classified as bullosis diabeticorum after excluding several differential diagnoses that are discussed. Bullosis diabeticorum is a rare blister formation located on the palmoplantar region, which is mainly observed in the case of diabetic patients. The clinical picture is characterized by tense bullae measuring up to 10 cm in diameter, containing clear to hemorrhagic fluid. Read More

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September 2018
1 Read

Topical pimecrolimus for paediatric cutaneous mastocytosis.

Clin Exp Dermatol 2018 Jul 20;43(5):559-565. Epub 2018 Feb 20.

Pediatric Dermatology Unit, Dana Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Background: Most cases of paediatric cutaneous mastocytosis (CM) occur before the age of 2 years, and regression occurs in only 67% of children. Given the absence of any specific therapy, CM is usually treated symptomatically. A few publications have reported the beneficial effect of calcineurin inhibitors for CM. Read More

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July 2018
1 Read

Intense pulsed light is effective in treating postburn hyperpigmentation and telangiectasia in Chinese patients.

J Cosmet Laser Ther 2018 Feb 16:1-6. Epub 2018 Feb 16.

a Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University , Xi'an, Shaanxi Province , China.

Intense pulsed light (IPL) has been used to treat postinflammatory hyperpigmentation and telangiectasia in Fitzpatrick type I -II skin. However, its therapeutic effects after superficial second-degree burns in Asian populations with Fitzpatrick type III-IV skin are uncertain. Thirty-five Han Chinese patients with facial or hand hyperpigmentation and telangiectasia due to second-degree fire burns received treatment with IPL. Read More

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February 2018
30 Reads

Pigmentation Disorders: Diagnosis and Management.

Am Fam Physician 2017 Dec;96(12):797-804

Norton Audobon Hospital, Louisville, KY, USA.

Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules. These conditions are generally benign but can be distressing to patients. Read More

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December 2017
23 Reads

Allergic Proctocolitis Is a Risk Factor for Functional Gastrointestinal Disorders in Children.

J Pediatr 2018 Apr 17;195:128-133.e1. Epub 2018 Jan 17.

Department of Medical and Surgical Sciences, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy. Electronic address:

Objective: To test the hypothesis that allergic proctocolitis, a cause of self-limiting rectal bleeding in infants, can predispose to the development of functional gastrointestinal disorders (FGIDs) later in childhood.

Study Design: We studied a cohort of 80 consecutive patients diagnosed with allergic proctocolitis. Their sibling or matched children presenting to the same hospital for minor trauma served as controls. Read More

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April 2018
3 Reads
3.790 Impact Factor

Fixed Drug Eruption to Supplement Containing Ginkgo Biloba and Vinpocetine: A Case Report and Review of Related Cutaneous Side Effects.

Authors:
Philip R Cohen

J Clin Aesthet Dermatol 2017 Oct 1;10(10):44-47. Epub 2017 Oct 1.

Dr. Cohen is from the Department of Dermatology at the University of California San Diego, La Jolla, California.

Fixed drug eruption is a cutaneous reaction to a systemic agent that typically presents as an annular or oval erythematous patch or blister and subsequently resolves with postinflammatory hyperpigmentation at the site. leaf extract and vinpocetine are nutritional supplements used to enhance memory in patients with dementia and age-related memory impairment conditions such as Alzheimer's disease. To describe a fixed drug eruption in a man who repeatedly developed pruritus and macular erythema on his distal penile shaft after ingesting a natural product containing and vinpocetine. Read More

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October 2017
10 Reads

A split-face, single-blinded, randomized controlled comparison of alexandrite 755-nm picosecond laser versus alexandrite 755-nm nanosecond laser in the treatment of acquired bilateral nevus of Ota-like macules.

J Am Acad Dermatol 2018 Sep 27;79(3):479-486. Epub 2017 Dec 27.

Department of Dermatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

Background: Q-switched alexandrite lasers (QSALs) have been used for the treatment of acquired bilateral nevus of Ota-like macules (ABNOMs). Currently, picosecond alexandrite laser (PSAL) pulses have become available for pigmentary disorders. However, no studies have compared PSAL and QSAL in the treatment of ABNOM. Read More

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September 2018
16 Reads

[Lichen nitidus and lichen striatus].

Authors:
I Stolze H Hamm

Hautarzt 2018 Feb;69(2):121-126

Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Würzburg, Josef-Schneider-Str. 2, 97080, Würzburg, Deutschland.

Lichen nitidus is a rare, chronic dermatosis which occurs more often in children than in adults. It presents with tiny, monomorphous, lichenoid, mostly asymptomatic papules in regional or disseminated distribution which show a pathognomonic histological pattern. The pathogenesis is unclear; however, immunologic phenomena and genetic factors are under discussion. Read More

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February 2018
5 Reads

Motorized spiral colonoscopy: a first single-center feasibility trial.

Endoscopy 2018 05 18;50(5):518-523. Epub 2017 Dec 18.

Department of Gastroenterology, Evangelisches Krankenhaus Düsseldorf, Düsseldorf, Germany.

Background: Cecal intubation rate represents a key procedural quality parameter in diagnostic colonoscopy. However, even experienced investigators report 10 % of all colonoscopies to be difficult and intubation of the cecum is sometimes impossible. A recently developed novel motorized spiral endoscope might potentially overcome some limitations of standard colonoscopy by actively pleating the bowel onto the endoscope. Read More

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May 2018
2 Reads
5.050 Impact Factor

Compression stockings as an effective treatment for erythema nodosum: Case series.

Int J Womens Dermatol 2017 Dec 29;3(4):231-233. Epub 2017 Sep 29.

Department of Medicine, Division of Dermatology, University of Arizona, Tucson, AZ.

Erythema nodosum (EN) is a septal panniculitis that is characterized clinically by tender, erythematous, subcutaneous nodules that are predominately localized on the pretibial lower legs. EN affects women more than men and can be idiopathic or secondary to another disease process such as infection or an immune response. Treatment options for erythema nodosum are suboptimal and often involve significant side effects or require a change in lifestyle. Read More

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December 2017
1 Read

Microneedling: a new approach for treating textural abnormalities and scars.

Semin Cutan Med Surg 2017 Dec;36(4):155-163

Chicago Cosmetic Surgery and Dermatology, Chicago, Illinois, USA.

Microneedling is a minimally invasive procedure wherein small holes are created across the stratum corneum while keeping the epidermis partially intact. This produces microchannels that increase skin permeability and simultaneously stimulate growth factor release. Since the epidermis is retained, microneedling has less risk of infection, postinflammatory hyperpigmentation, and scarring compared to other resurfacing modalities. Read More

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December 2017
3 Reads

Postinflammatory Hyperpigmentation: Epidemiology, Clinical Presentation, Pathogenesis and Treatment.

Am J Clin Dermatol 2018 Aug;19(4):489-503

Mount Sinai St. Luke's and West, 1090 Amsterdam Avenue, Suite 11B, New York, NY, 10025, USA.

Postinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis that develops following cutaneous inflammation. Common causes of PIH include intrinsic skin conditions (e.g. Read More

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August 2018
14 Reads

Treatment of Melasma and Post-Inflammatory Hyperpigmentation by a Picosecond 755-nm Alexandrite Laser in Asian Patients.

Ann Dermatol 2017 Dec 30;29(6):779-781. Epub 2017 Oct 30.

Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

The picosecond lasers have shown to effectively treat tattoo pigments that are intractable to previous multiple Q-switched (QS) laser treatments. Therefore we hypothesized that a picosecond laser would show better efficacy with minimal adverse events in the treatment of melasma and post-inflammatory hyperpigmentation (PIH) that are difficult to treat with conventional QS lasers. Two patients with melasma and one patient with PIH were treated with a Picosecond 755-nm Alexandrite Laser (Cyanosure, USA). Read More

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December 2017
23 Reads

Increased Skin Irritation by Hydroquinone and Rsetinoic Acid Used in Combination.

Ann Dermatol 2017 Dec 30;29(6):715-721. Epub 2017 Oct 30.

Department of Dermatology, Dongguk University Ilsan Hospital, Goyang, Korea.

Background: Hydroquinone (HQ) is frequently combined with retinoic acid (RA) to enhance lightening efficacy, which may also affect skin irritancy. Although skin irritation leads to postinflammatory hyperpigmentation, little research has been performed to compare skin irritancy between each component and the combination.

Objective: This study was done to examine whether HQ-RA combination increased skin irritation induced by HQ or RA alone. Read More

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December 2017
1 Read

Novel device-based acne treatments: comparison of a 1450-nm diode laser and microneedling radiofrequency on mild-to-moderate acne vulgaris and seborrhoea in Korean patients through a 20-week prospective, randomized, split-face study.

J Eur Acad Dermatol Venereol 2018 Apr 15;32(4):639-644. Epub 2017 Dec 15.

Department of Dermatology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.

Background: While device-based acne treatments are widely applied for patients not tolerating conventional medications, related controlled studies have been still limited. Recently, non-ablative 1450-nm diode laser (DL) and fractional microneedling radiofrequency (FMR) have been effectively used for acne, in addition to well-recognized dermal remodelling effects.

Objective: To compare the clinical course of acne treatment between DL and FMR. Read More

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April 2018
25 Reads