479 results match your criteria Postinflammatory Hyperpigmentation


Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial.

Int J Dermatol 2020 Jul 24;59(7):804-812. Epub 2020 May 24.

Dermatology Unit, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.

Objective: Antibiotics and retinoids have been used for acne vulgaris for decades. Though effective, each has its own drawbacks. Chemical peels have been used for treatment of acne vulgaris with inadequate clinical evidence. Read More

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http://dx.doi.org/10.1111/ijd.14948DOI Listing

Photoprotection beyond ultraviolet radiation: A review of tinted sunscreens.

J Am Acad Dermatol 2020 Apr 23. Epub 2020 Apr 23.

Department of Dermatology, Henry Ford Hospital, Detroit, Michigan. Electronic address:

Ultraviolet radiation and visible light both have biologic effects on the skin. Visible light can induce erythema in light-skinned individuals and pigmentation in dark-skinned individuals. Broad-spectrum sunscreens protect against ultraviolet radiation but do not adequately protect against visible light. Read More

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http://dx.doi.org/10.1016/j.jaad.2020.04.079DOI Listing

Periorbital postinflammatory hyperpigmentation after plasma exeresis.

Dermatol Ther 2020 May 29;33(3):e13404. Epub 2020 Apr 29.

Doctors At Soap, Private Cosmetic Clinic, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/dth.13404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317400PMC

Photoaging Reversibility in Asian Patients With Melasma Treated Using Picosecond Lasers With Diffractive Lens Array: A 1-Year Prospective Observational Cohort Study.

Dermatol Surg 2020 Apr 6. Epub 2020 Apr 6.

Department of Cosmeceutics, Graduate Institute of Cosmeceutics, China Medical University, Taichung, Taiwan (R.O.C.).

Background: Picosecond lasers appear to be effective and safe in treating pigmentation and photoaging disorders through laser-induced optical breakdown.

Objective: To analyze the feasibility of photorejuvenation using picosecond lasers with diffractive lens array (DLA) in patients with melasma.

Methods: Ten Asian (N = 10) women with melasma and Fitzpatrick skin Type IV were enrolled and treated using 755-nm picosecond alexandrite lasers with DLA. Read More

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http://dx.doi.org/10.1097/DSS.0000000000002405DOI Listing
April 2020
2.109 Impact Factor

Trichloroacetic acid model to accurately capture the efficacy of treatments for postinflammatory hyperpigmentation.

Arch Dermatol Res 2020 Apr 6. Epub 2020 Apr 6.

Department of Dermatology, Henry Ford Hospital, 3031 West Grand Blvd, Detroit, MI, 48202, USA.

Postinflammatory hyperpigmentation (PIH) occurs following cutaneous injury and is common following resolution of acne especially in patients with skin of color. The objective of this study was to further validate a trichloroacetic acid (TCA)-induced PIH model and compare it to acne-induced PIH using topical bakuchiol, a botanical extract that has been shown to have antimicrobial, anti-inflammatory, antioxidant, and antiacne properties. A prospective, non-randomized clinical trial was conducted on subjects with skin phototypes IV-VI with a history of acne-induced PIH. Read More

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http://dx.doi.org/10.1007/s00403-020-02071-4DOI Listing

Efficacy of a wound-dressing biomaterial on prevention of postinflammatory hyperpigmentation after suction blister epidermal grafting in stable vitiligo patients: a controlled assessor-blinded clinical study with in vitro bioactivity investigation.

Arch Dermatol Res 2020 Feb 27. Epub 2020 Feb 27.

Department of Dermatology, Huashan Hospital, Fudan University, No. 12th Middle Wulumuqi Road, Shanghai, 200040, China.

Postinflammatory hyperpigmentation (PIH) is a common disfiguring complication following inflammatory dermatoses and cosmetic procedures in dark-skinned individuals. Anti-inflammatory and repairing agents targeting primary inflammation and injury are becoming promising choices for preventing PIH. The aim of this active-controlled, assessor-blinded, intra-individual monocentric study was to evaluate the preventive effect of a wound-dressing biomaterial, mussel adhesive protein (MAP) in the suction blister-induced PIH model. Read More

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http://dx.doi.org/10.1007/s00403-020-02049-2DOI Listing
February 2020
2.270 Impact Factor

UK-based dermatologist online survey on the current practice and training in the management of melasma and postinflammatory hyperpigmentation.

Clin Exp Dermatol 2020 Jun 25;45(4):483-484. Epub 2020 Mar 25.

Department of Dermatology, University Hospitals Birmingham, UK.

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http://dx.doi.org/10.1111/ced.14197DOI Listing

Intense Pulsed-light Therapy Significantly Improves Keratosis Pilaris: A Randomized, Double-blind, Sham Irradiation-controlled Trial.

J Clin Aesthet Dermatol 2019 Oct 1;12(10):E53-E57. Epub 2019 Oct 1.

Drs. Maitriwong, Tangkijngamvong, and Asawanonda are with Division of Dermatology in the Department of Medicine, Faculty of Medicine at the Chulalongkorn University in Bangkok, Thailand.

Keratosis pilaris (KP) is a common benign follicular disorder for which various topical and laser treatments have been used, with limited efficacy. We evaluated the efficacy of intense pulsed light (IPL) therapy for the reduction of skin roughness, erythema, and hyperpigmentation in Thai subjects with KP. Twenty-four Thai patients with untreated KP on the upper outer arms were enrolled in a randomized, double-blind study. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937144PMC
October 2019

Dermoscopy and VISIA imager evaluations of non-insulated microneedle radiofrequency versus fractional CO laser treatments of striae distensae.

J Eur Acad Dermatol Venereol 2020 Feb 6. Epub 2020 Feb 6.

Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Backgrounds: Striae distensae (SD) has a known psychological impact due to the resulting cosmetic disfigurement. Many treatment modalities have been used over the years, but no standard interventions or evaluation methods have been proposed to date.

Objective: We compared the efficacy and safety of non-insulated microneedle radiofrequency (NIMRF) and fractional CO laser treatments of SD by objective measurements with dermoscopy and VISIA. Read More

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http://dx.doi.org/10.1111/jdv.16266DOI Listing
February 2020

The Role of Sunscreen in Melasma and Postinflammatory Hyperpigmentation.

Indian J Dermatol 2020 Jan-Feb;65(1):5-10

Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA.

Photosensitive conditions such as melasma and postinflammatory hyperpigmentation (PIH) are exacerbated by exposure to ultraviolet (UV) rays and visible light making sunscreen use an essential component of treatment. This is especially true in skin of color patients who are less likely to use photoprotection, even if diagnosed with these photoexacerbated conditions. We aimed to evaluate the body of literature to provide evidence for the use of sunscreen in the treatment of melasma and PIH. Read More

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http://dx.doi.org/10.4103/ijd.IJD_295_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986132PMC
February 2020

Development and Initial Validation of a Multidimensional Acne Global Grading System Integrating Primary Lesions and Secondary Changes.

JAMA Dermatol 2020 Jan 29. Epub 2020 Jan 29.

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

Importance: The qualitative grading of acne is important for routine clinical care and clinical trials, and although many useful systems exist, no single acne global grading system has had universal acceptance. In addition, many current instruments focus primarily on evaluating primary lesions (eg, comedones, papules, and nodules) or exclusively on signs of secondary change (eg, postinflammatory hyperpigmentation, scarring).

Objectives: To develop and validate an acne global grading system that provides a comprehensive evaluation of primary lesions and secondary changes due to acne. Read More

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http://dx.doi.org/10.1001/jamadermatol.2019.4668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990806PMC
January 2020

Ecchymosis combined with postinflammatory hyperpigmentation associated with acupuncture therapy: An observational study of 167 subjects.

Medicine (Baltimore) 2020 Jan;99(4):e18721

Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences.

To evaluate the incidence of ecchymosis combined with postinflammatory hyperpigmentation (ECPH) over the course of 10 sessions of acupuncture therapy and to examine associated factors.An observational study was conducted from March 7, 2017 through March 6, 2018. This study included a total of 167 subjects and 326 bodily locations where acupuncture needles had been inserted. Read More

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http://dx.doi.org/10.1097/MD.0000000000018721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004638PMC
January 2020

Lichen planus related to transforming growth factor beta inhibitor in a patient with metastatic chondrosarcoma: a case report.

J Cutan Pathol 2020 May 27;47(5):490-493. Epub 2020 Jan 27.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Transforming growth factor-beta1 (TGF-β1) is expressed in normal epidermis. TGF-β1 potently inhibits keratinocyte proliferation and immunomodulatory properties, mainly by suppressing immune responses to self-antigens. Lichen planus (LP) is a form of dermatitis caused by cell-mediated immune dysfunction, but the exact pathogenic pathways are unknown, which poses therapeutic challenges. Read More

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http://dx.doi.org/10.1111/cup.13645DOI Listing
May 2020
1.560 Impact Factor

Prevalence of pigmentary disorders: A cross-sectional study in public hospitals in Durban, South Africa.

Int J Womens Dermatol 2019 Dec 13;5(5):345-348. Epub 2019 Jul 13.

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Background: Pigmentary disorders are common in patients with skin of color and one of the top five most common dermatologic diagnoses in individuals of African descent. Little is known about the spectrum of pigmentary disorders in South Africa's second largest province, KwaZulu Natal.

Objective: This study aimed to determine the profile of pigmentary disorders in patients at five outpatient public hospital skin clinics in Durban, South Africa. Read More

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http://dx.doi.org/10.1016/j.ijwd.2019.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938902PMC
December 2019

Lichen Planus Severity Index: A new, valid scoring system to assess the severity of cutaneous lichen planus.

Indian J Dermatol Venereol Leprol 2020 Mar-Apr;86(2):169-175

Department of Dermatology, Krishna Institute of Medical Sciences, Karad, Maharashtra, India.

Introduction: Lichen planus is a chronic autoimmune inflammatory disorder. At present, there is a lack of any specific scoring system to judge the severity of cutaneous lichen planus. Hence, a study was undertaken to establish and validate a system to define the severity of cutaneous lichen planus, i. Read More

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http://dx.doi.org/10.4103/ijdvl.IJDVL_650_17DOI Listing
January 2020

The color of skin: brown diseases of the skin, nails, and mucosa.

Clin Dermatol 2019 Sep - Oct;37(5):487-506. Epub 2019 Jul 23.

Department of Dermatology, Cerrahpaşa Medical Faculty, Istanbul University-Cerrahpaşa, Istanbul, Turkey.

Brown diseases comprise disorders leading to hyperpigmentation in skin and nails. Melasma is an acquired skin disorder that is characterized by brownish macules that typically occur on the face. Schamberg disease, also known as progressive pigmented purpura, is characterized by brown pigmentation with pepper spots on their edges. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2019.07.007DOI Listing

Prominent Transepidermal Melanin Deposition Is a Distinguishing Histopathological Feature of Melasma: A Clinicopathologic Study.

Dermatology 2019 Nov 20:1-3. Epub 2019 Nov 20.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.

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http://dx.doi.org/10.1159/000504408DOI Listing
November 2019

Factors affecting the outcome of the suction blisters using two different harvesting techniques in vitiligo patients.

J Cosmet Dermatol 2020 Jul 20;19(7):1723-1729. Epub 2019 Nov 20.

Department of Dermatology, STD's and Andrology, Matay Central Hospital, Minia, Egypt.

Background: Suction blister grafting (SBG) technique has been used for long to treat various skin conditions. Different suction methods have been used such as syringes, Chinese cups, and suction device. There are some limitations of its use as time consumption, failure of induction or incomplete blister formation and pain. Read More

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http://dx.doi.org/10.1111/jocd.13222DOI Listing
July 2020
4 Reads

Tretinoin 0.05% Lotion for the Once-Daily Treatment of Moderate-to-Severe Acne Vulgaris: Impact of Gender and Race on Efficacy and Safety

J Drugs Dermatol 2019 Nov;18(11):1128-1138

Background: There has been an increasing interest in gender and racial differences both in the pathogenesis and treatment of acne vulgaris (acne), and postinflammatory hyperpigmentation (PIH) is a major concern in patients of color. Female acne patients report more anxiety and depression with acne improvement positively influencing Quality of Life (QoL) than their male counterparts, and there are differences in acne presentation. The first lotion formulation of tretinoin was developed using novel polymeric emulsion technology to provide an important alternative option to treat these acne patients, especially those who may be sensitive to the irritant effects of other tretinoin formulations. Read More

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November 2019

The emerging importance of tranexamic acid in dermatology.

Clin Exp Dermatol 2020 Jun 30;45(4):445-449. Epub 2019 Oct 30.

Dermatological Surgery and Laser Unit, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Tranexamic acid (TA) is an antifibrinolytic agent, increasingly recognized as being of utility for a wide variety of skin diseases. We review the evidence supporting the use of TA for a range of dermatological indications, including (among others) melasma, postinflammatory hyperpigmentation, urticaria, angio-oedema and haemostasis, in addition to practical considerations of its use by dermatologists. Read More

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http://dx.doi.org/10.1111/ced.14115DOI Listing

Patient Preferences and Comparative Outcomes Regarding Cryosurgery versus Electrodesiccation in the Removal of Truncal Seborrheic Keratoses.

J Clin Aesthet Dermatol 2019 Sep 1;12(9):E53-E56. Epub 2019 Sep 1.

Drs. Ethington, Surprenant, Rovner, Reserva, Swan, Lee, and Mr. Murphy are with the Divison of Dermatology at Loyola University in Maywood, Illinois. Ms. Andia is with the Stritch School of Medicine at Loyola University in Maywood, Illinois.

Seborrheic keratoses (SKs) are one of the most common benign epithelial tumors seen by dermatologists. Many people elect to have these lesions removed, most commonly by way of cryosurgery or electrodesiccation. We sought to evaluate the comparative efficacy and patient preferences regarding cryosurgery and electrodesiccation for the treatment of truncal SK lesions. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777698PMC
September 2019

Postinflammatory hyperpigmentation following treatment of hyperkeratosis lenticularis perstans with tazarotene cream 0.1.

Cutis 2019 Aug;104(2):E37-E38

Department of Dermatology, University of Texas Medical Branch at Galveston, USA.

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August 2019
3 Reads

Lasers for reduction of unwanted hair in skin of colour: a systematic review and meta-analysis.

J Eur Acad Dermatol Venereol 2020 May 6;34(5):948-955. Epub 2019 Nov 6.

Dermatology Department, Kasr Al Ainy Hospital, Cairo University, Giza, Egypt.

Light-based therapies are one of the most effective and widely used strategies for removal of undesired hair, with a broadly favourable safety profile. However, subjects with pigmented skin are found to be more prone to laser-related adverse events. While prolonged pulse-width and longer treatment duration were proposed to minimize adverse events, the optimal treatment option among available phototherapy modalities - long-pulsed (Nd:YAG), pulsed diode and alexandrite lasers as well as intense pulsed light (IPL) - remains unclear, particularly for skin of colour. Read More

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http://dx.doi.org/10.1111/jdv.15995DOI Listing
May 2020
1 Read

Primary Language in Relation to Knowledge of Diagnosis and Sun-Related Behaviors in Adults with Sun-Exacerbated Dermatoses.

Int J Environ Res Public Health 2019 10 2;16(19). Epub 2019 Oct 2.

Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA.

Objective: To evaluate how patients' primary spoken language influences the understanding of their disorder and their subsequent sun-related behaviors.

Methods: This was a cross-sectional study conducted between February 2015 and July 2016 in two outpatient dermatology clinics among 419 adults with a sun-exacerbated dermatosis. The primary outcome was a successful match between the patient-reported diagnosis on a survey and the dermatologist-determined diagnosis. Read More

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http://dx.doi.org/10.3390/ijerph16193710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801846PMC
October 2019

The efficacy and safety of microneedle monopolar radiofrequency for the treatment of periorbital wrinkles.

J Dermatolog Treat 2019 Sep 10:1-5. Epub 2019 Sep 10.

Department of Dermatology, College of Medicine, Seoul National University, Seoul National University Bundang Hospital , Gyeonggi , Korea.

Treatment of periorbital wrinkles is a challenging task because of its anatomical significance and delicate nature. The aim of this study was to evaluate the efficacy and safety of a microneedle monopolar radiofrequency (RF) device for treating periorbital wrinkles. This retrospective study involved 21 patients who were treated for periorbital wrinkles using a RF device. Read More

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http://dx.doi.org/10.1080/09546634.2019.1662880DOI Listing
September 2019
1 Read

Efficacy and Safety of Ablative Resurfacing With A High-Energy 1,064 Nd-YAG Picosecond-domain Laser for the Treatment of Facial Acne Scars in Asians.

Lasers Surg Med 2020 Jun 4;52(5):389-395. Epub 2019 Sep 4.

Department of Dermatology, Taipei Veterans General Hospital, Taipei, 11221, Taiwan.

Objectives: There have been few studies regarding the use of a picosecond-domain laser for acne scars in Asians. This prospective study evaluated the efficacy and safety of a high-energy 1,064 nm Nd:YAG picosecond-domain laser for ablation and resurfacing of facial acne scars in Asians.

Methods: Subjects were treated with a 1,064 nm picosecond laser (8 mm spot, 0. Read More

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http://dx.doi.org/10.1002/lsm.23151DOI Listing
June 2020
1 Read

Development and accuracy of an artificial intelligence algorithm for acne grading from smartphone photographs.

Exp Dermatol 2019 11 9;28(11):1252-1257. Epub 2019 Sep 9.

Department of Dermatology, Nantes University Hospital, Nantes, France.

We developed an artificial intelligence algorithm (AIA) for smartphones to determine the severity of facial acne using the GEA scale and to identify different types of acne lesion (comedonal, inflammatory) and postinflammatory hyperpigmentation (PIHP) or residual hyperpigmentation. Overall, 5972 images (face, right and left profiles) obtained with smartphones (IOS and/or Android) from 1072 acne patients were collected. Three trained dermatologists assessed the acne severity for each patient. Read More

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http://dx.doi.org/10.1111/exd.14022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972662PMC
November 2019
1 Read

Therapeutic Insights in Melasma and Hyperpigmentation Management

J Drugs Dermatol 2019 Aug;18(8):718-729

Melasma and postinflammatory hyperpigmentation (PIH) are the most common forms of dyschromia in patients with skin of color. Both are associated with a high psychological burden of disease. To exacerbate this burden, the need for treatment is chronic, and the results are often suboptimal in the eyes of the patient. Read More

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August 2019
3 Reads

Efficacy and Safety Evaluation of Picosecond Alexandrite Laser with a Diffractive Lens Array for Treatment of Melasma in Asian Patients by VISIA Imaging System.

Photobiomodul Photomed Laser Surg 2019 Sep 14;37(9):559-566. Epub 2019 Aug 14.

Department of Applied Cosmetology, Master's Program of Cosmetic Science, Hung Kuang University, Taichung, Taiwan (R.O.C.).

To evaluate the efficacy and safety of picosecond (ps) 755-nm alexandrite laser with a diffractive lens array (DLA) generating laser-induced optical breakdown, which may be beneficial for melasma treatment. Melasma is notorious for difficult to treat with any modality setting. Recently, picosecond alexandrite laser with DLA seems promising for dealing with it without intolerable complications. Read More

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http://dx.doi.org/10.1089/photob.2019.4644DOI Listing
September 2019
7 Reads

Microneedling Treatment of Striae Distensae in Light and Dark Skin With Long-Term Follow-Up.

Dermatol Surg 2020 Apr;46(4):459-464

MKL Dermatology, Vancouver, British Columbia, Canada.

Background: Striae distensae have notoriously been difficult to treat due to their extensive involvement of nonfacial skin. Microneedling with its lack of thermal injury during microneedling treatment renders it a viable treatment option in darker skin tones and nonfacial regions due to the reduced risk of postinflammatory hyperpigmentation.

Objective: To describe the clinical results and side effects of microneedling in a series of 25 individuals with striae distensae. Read More

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http://dx.doi.org/10.1097/DSS.0000000000002081DOI Listing
April 2020
5 Reads

The effect of human umbilical cord blood-derived mesenchymal stem cell media containing serum on recovery after laser treatment: A double-blinded, randomized, split-face controlled study.

J Cosmet Dermatol 2020 Mar 22;19(3):651-656. Epub 2019 Jul 22.

Department of Dermatology and Cutaneous Biology Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Background: Ablative CO2 fractional laser (AFL) is a common cosmetic procedure to improve skin laxity. However, due to prolonged downtime and the risk of postinflammatory hyperpigmentation, laser-assisted delivery of active ingredients as post-laser treatment has gained interest in past years. Among various active ingredients, human umbilical cord blood-derived mesenchymal stem cells (hUCBMSCs) can be a promising agent promoting skin regeneration. Read More

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http://dx.doi.org/10.1111/jocd.13063DOI Listing
March 2020
4 Reads

A Prospective Randomized Controlled Study of Oral Tranexamic Acid for the Prevention of Postinflammatory Hyperpigmentation After Q-Switched 532-nm Nd:YAG Laser for Solar Lentigines.

Lasers Surg Med 2019 12 14;51(10):850-858. Epub 2019 Jul 14.

Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Background And Objectives: Q-switched (QS) 532-nm Nd:YAG laser is one of the treatment options for solar lentigines (SLs). However, the high incidence of postinflammatory hyperpigmentation (PIH) is concerning, especially in dark-complexioned skin. Tranexamic acid (TA) can decrease melanogenesis and has been used to treat melasma. Read More

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http://dx.doi.org/10.1002/lsm.23135DOI Listing
December 2019
9 Reads

Patient-Reported Outcomes in Acne Patients With Skin of Color Using Adapalene 0.3%-Benzoyl Peroxide 2.5%: A Prospective Real-World Study

J Drugs Dermatol 2019 Jun;18(5):514

Background: Patients with skin of color (SOC) and Fitzpatrick skin types (FST) IV–VI frequently develop acne. Objective: Evaluate subject-reported outcomes after treatment with adapalene 0.3%/ benzoyl peroxide 2. Read More

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June 2019
6 Reads

Low-fluence Q-switched Nd:YAG 1064-nm laser versus Q-switched Nd:YAG 532-nm laser in the treatment of hyperpigmented lips: a prospective, randomized, controlled, evaluator-blinded trial.

Lasers Med Sci 2020 Feb 8;35(1):165-171. Epub 2019 Jun 8.

Skin Center, Srinakharinwirot University, Bangkok, 10110, Thailand.

Lip hyperpigmentation is an esthetic problem. Clinical data from controlled comparative studies is insufficient to support the efficacy of laser treatments for hyperpigmented lips. This study is aimed to compare the efficacy of low-fluence Q-switched Nd:YAG 1064-nm laser (LFQS 1064-nm) versus Q-switched Nd:YAG 532-nm laser (QS 532-nm) for the treatment of hyperpigmented lips. Read More

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http://dx.doi.org/10.1007/s10103-019-02814-4DOI Listing
February 2020
12 Reads

Clinical and pathological characterization of oral mucosal 'lichen planus-like lesions' in patients with pemphigus vulgaris: An observational study.

Indian J Dermatol Venereol Leprol 2020 May-Jun;86(3):278-283

Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: Lichen planus-like lesions on oral mucosa occasionally occur in Indian patients with pemphigus vulgaris. Its significance, both clinical and pathological, is yet to be elucidated.

Aims And Objectives: To study the clinical and pathological characteristics of clinically apparent oral mucosal lichen planus-like lesions in pemphigus patients and to assess their relation with pemphigus disease activity. Read More

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http://dx.doi.org/10.4103/ijdvl.IJDVL_129_18DOI Listing
April 2019
8 Reads
1.325 Impact Factor

Laser Treatment of Skin of Color for Medical and Aesthetic Uses With a New 650-Microsecond Nd:YAG 1064nm Laser

J Drugs Dermatol 2019 Apr;18(4):s135-137

Individuals with skin of color are a rapidly growing portion of the cosmetic procedures market. There are unique challenges to treating skin conditions in skin of color patients. This article and roundtable discussion focus on the use of energy-based modalities, particularly a 650-microsecond 1064nm laser that delivers energy in a collimated beam. Read More

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April 2019
12 Reads

Assessment of Melanogenesis in a Pigmented Human Tissue-Cultured Skin Equivalent.

Indian J Dermatol 2019 Mar-Apr;64(2):85-89

Department of Dermatology, Venereology, and Allergology, Goethe University Hospital, Frankfurt/Main, Germany.

Background: Organotypic tissue-cultured skin equivalents are used for a broad range of applications either as possible substitute for animal tests or for transplantation in patient-centered care.

Aims: In this study, we implemented melanocytes in a tissue-cultured full-thickness skin equivalent, consisting of epidermis and dermis. The versatility of this skin-like model with respect to pigmentation and morphological criteria was tested. Read More

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http://www.e-ijd.org/text.asp?2019/64/2/85/254158
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http://dx.doi.org/10.4103/ijd.IJD_410_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440179PMC
April 2019
21 Reads

Case series of post-purpuric darkness on the periorbital area after aesthetic surgery.

Dermatol Ther 2019 07 25;32(4):e12922. Epub 2019 Apr 25.

Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.

Periorbital hyperpigmentation (POH) is a common condition encountered in dermatology practice. POH is caused by various exogenous and endogenous factors including excessive pigmentation, postinflammatory hyperpigmentation (PIH) secondary to eczema, periorbital edema, excessive vascularity, and aging. Recently, we have experienced several patients who complained of POH with an unusual pattern. Read More

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http://dx.doi.org/10.1111/dth.12922DOI Listing
July 2019
17 Reads

Efficacy of bleomycin application on periungual warts after treatment with ablative carbon dioxide fractional laser: a pilot study.

J Dermatolog Treat 2020 Jun 6;31(4):410-414. Epub 2019 May 6.

Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Republic of Korea.

Treating periungual warts is a therapeutic challenge. Treatments are often ineffective and may cause complications including permanent nail changes, pain, and scaring. Translesional bleomycin delivery via the multipuncture technique is now reported. Read More

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https://www.tandfonline.com/doi/full/10.1080/09546634.2019.1
Publisher Site
http://dx.doi.org/10.1080/09546634.2019.1605136DOI Listing
June 2020
26 Reads

Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial.

J Cosmet Dermatol 2019 Dec 4;18(6):1751-1757. Epub 2019 Apr 4.

Department of Pediatrics, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.

Introduction: Fractional carbon dioxide (FrCO ) laser is effective for atrophic acne scar treatment, but unavoidable downtime. Meanwhile, postoperative topical steroid decreases the downtime, yet still possibly increases other steroid side effects.

Objective: To evaluate the efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese (experimental cream) versus 0. Read More

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http://dx.doi.org/10.1111/jocd.12951DOI Listing
December 2019
17 Reads

Novel tretinoin 0.05% lotion for the once-daily treatment of moderate-to-severe acne vulgaris: assessment of safety and tolerability in subgroups.

J Dermatolog Treat 2020 Mar 2;31(2):160-167. Epub 2019 Apr 2.

Bausch Health Americas, Inc, Petaluma, CA, USA.

Topical tretinoin's role in acne has been established through evidence-based guidelines. Cutaneous irritation and potential to cause or exacerbate postinflammatory hyperpigmentation (PIH) may limit use. Evaluate safety and tolerability of novel polymeric formulation of tretinoin 0. Read More

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http://dx.doi.org/10.1080/09546634.2019.1587884DOI Listing
March 2020
13 Reads

755 nm picosecond laser for facial atrophic scar-Case reports of long-term clinical efficacy following up.

J Cosmet Dermatol 2019 Jun 28;18(3):778-782. Epub 2019 Mar 28.

P-Skin Professional Clinic, Kaohsiung, Taiwan.

Introduction: Acne vulgaris is one of the most common dermatological problems in Asia. While the disease itself is self-limited and temporary, the dystrophic texture changes after the inflammatory process are often a serious aesthetic concern. Many energy-based devices have seen good results in treating atrophic acne scars, and the picosecond laser with specific lens is one of the newer options, and lack reports on its long-term efficacy. Read More

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http://dx.doi.org/10.1111/jocd.12925DOI Listing
June 2019
5 Reads

Acne and Rosacea: Special Considerations in the Treatment of Patients With Latin American Ancestry

J Drugs Dermatol 2019 Mar;18(3):s124-126

Acne is a common disease among patients with Latin American ancestry. Its presentation is very similar to that in all skin types, but nodulocystic acne is more frequent in patients with oily and darker skin than in white Caucasians. Acne sequelae in patients with Latin American ancestry and with darker skin include postinflammatory hyperpigmentation (PIH) and atrophic and hypertrophic scars or keloids, with PIH being the most common complication affecting the quality of life of patients. Read More

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March 2019
11 Reads

Managing postinflammatory hyperpigmentation in pediatric patients with skin of color.

Authors:
Candrice R Heath

Cutis 2019 02;103(2):71-73

Department of Dermatology, Lewis Katz School of Medicine, Temple University Hospital, Philadelphia, Pennsylvania, USA.

Postinflammatory hyperpigmentation (PIH) is common in patients with skin of color. Notably, the US population of children with skin of color is growing rapidly. Postinflammatory hyperpigmentation can be quite distressing in pediatric patients, particularly among adolescents and their parents/guardians. Read More

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February 2019
5 Reads

Comparison of a picosecond alexandrite laser versus a Q-switched alexandrite laser for the treatment of nevus of Ota: A randomized, split-lesion, controlled trial.

J Am Acad Dermatol 2019 Mar 16. Epub 2019 Mar 16.

Department of Cosmetic Laser Surgery, Hospital for Skin Disease and Institute of Dermatology, Peking Union Medical College and Chinese Academy of Medical Sciences, Nanjing, China. Electronic address:

Background: Novel picosecond lasers have been available for various pigmentary disorders. However, there are limited data directly comparing picosecond lasers and Q-switched lasers for treatment of nevus of Ota.

Objective: To compare the efficacy and safety of a picosecond alexandrite laser (PSAL) with a Q-switched alexandrite laser (QSAL) for the treatment of nevus of Ota. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.03.016DOI Listing
March 2019
2 Reads
4.449 Impact Factor

Laser treatment of hyperpigmented lesions: position statement of the European Society of Laser in Dermatology.

J Eur Acad Dermatol Venereol 2019 Jun 14;33(6):987-1005. Epub 2019 Mar 14.

National Institute of Laser Enhanced Sciences, Cairo University, Giza, Egypt.

Background: Lasers and intense pulsed light sources (IPLS) are proposed for the treatment of many pigmentary disorders. They are sometimes considered as magic tools able to remove any type of lesions. Although being the best option for several hyperpigmented lesions, they can also worsen some conditions and have potential side-effects. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jdv.15497
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http://dx.doi.org/10.1111/jdv.15497DOI Listing
June 2019
9 Reads

What's New in Pigmentary Disorders.

Dermatol Clin 2019 Apr 16;37(2):175-181. Epub 2019 Feb 16.

Department of Dermatology, Henry Ford Hospital System, 3031 West Grand Boulvard, Suite 800, Detroit, MI 48202, USA. Electronic address:

Pigmentary disorders are common and can be very distressing to patients. There is a need for better, standardized therapies. The authors review the most recent data for topical, systemic, light, and laser treatments for vitiligo, melasma, and postinflammatory hyperpigmentation. Read More

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http://dx.doi.org/10.1016/j.det.2018.12.008DOI Listing
April 2019
14 Reads

Pediatric toxic epidermal necrolysis treated successfully with infliximab.

Pediatr Dermatol 2019 May 4;36(3):342-345. Epub 2019 Mar 4.

Departments of Dermatology, Zealand University Hospital, Roskilde, Denmark.

Successful management of toxic epidermal necrolysis (TEN) with tumor necrosis factor-α inhibitors has been described in adults. We present a case of a 7-year-old boy with infection-associated TEN, diagnosed by typical clinical and histopathological features, most likely caused by Mycoplasma pneumoniae. Treatment with a single dose of infliximab 5 mg/kg intravenously on day 5 after the onset of symptoms was followed by cessation of all blister formation over 3 days and complete resolution within a week. Read More

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http://dx.doi.org/10.1111/pde.13778DOI Listing
May 2019
20 Reads

Insights on an in vivo model for postinflammatory hyperpigmentation.

Br J Dermatol 2019 09 13;181(3):598-599. Epub 2019 May 13.

Department of Dermatology, Henry Ford Hospital, Detroit, MI, U.S.A.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/bjd.17746
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http://dx.doi.org/10.1111/bjd.17746DOI Listing
September 2019
12 Reads