56,660 results match your criteria Postgraduate Medicine [Journal]


Glucocorticoid receptor (NR3C1) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians.

Exp Gerontol 2018 Dec 12. Epub 2018 Dec 12.

Mossakowski Medical Research Centre, PAS, Pawinskiego 5, 02-106 Warsaw, Poland; Medical Centre of Postgraduate Education, Marymoncka 99/103, 01-813 Warsaw, Poland. Electronic address:

Introduction: Polymorphism of the glucocorticoid receptor gene (NR3C1) may modify protein abundance or function and therefore disturb human homeostasis.

Methods: Variant frequencies of the three NR3C1 polymorphisms, rs2963154, rs10515522 and rs2918418, selected in silico as associated with longevity, was analyzed in 552 DNA samples from 95 to 106-year-old individuals and in 284 samples of cord blood DNA from newborns.

Results: Frequencies of the TT genotypes of rs2963154 and rs10515522, and of the rs291841 CC genotype, were higher in the long-lived study subjects (p = 0. Read More

View Article
December 2018

Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide.

Gastroenterology 2018 Dec 12. Epub 2018 Dec 12.

Unit of Internal Medicine and Hepatology (UIMH), Department of Medicine - DIMED, University of Padova, Padova, Italy. Electronic address:

Background And Aims: Bacterial infections are common and life-threatening in patients with cirrhosis. Little is known about the epidemiology of bacterial infections in different regions. We performed a multicenter prospective intercontinental study to assess the prevalence and outcomes of bacterial and fungal infections in patients with cirrhosis. Read More

View Article
December 2018

Flow-Mediated Drug Transport from Drug-Eluting Stents is Negligible: Numerical and In-vitro Investigations.

Ann Biomed Eng 2018 Dec 14. Epub 2018 Dec 14.

UNSW Sydney, Sydney, NSW, Australia.

Prior numerical studies have shown that the blood flow patterns surrounding drug-eluting stents can enhance drug uptake in stented arteries. However, these studies employed steady-state simulations, wherein flow and drug transport parameters remained constant with respect to time. In the present study, numerical simulations and in-vitro experiments were performed to determine whether luminal blood flow patterns can truly enhance drug uptake in stented arteries. Read More

View Article
December 2018

Upregulation of MLK4 promotes migratory and invasive potential of breast cancer cells.

Oncogene 2018 Dec 14. Epub 2018 Dec 14.

Laboratory of Experimental Medicine, Centre of New Technologies, University of Warsaw, Warsaw, Poland.

Metastasis to distant organs is a major cause for solid cancer mortality, and the acquisition of migratory and invasive phenotype is a key factor in initiation of malignancy. In this study we investigated the contribution of Mixed-Lineage Kinase 4 (MLK4) to aggressive phenotype of breast cancer cells. Our TCGA cancer genomic data analysis revealed that amplification or mRNA upregulation of MLK4 occurred in 23% of invasive breast carcinoma cases. Read More

View Article
December 2018

Enhancer Trapping and Annotation in Zebrafish Mediated with Sleeping Beauty, piggyBac and Tol2 Transposons.

Genes (Basel) 2018 Dec 13;9(12). Epub 2018 Dec 13.

Institute of Mobilome and Genome, College of Animal Science & Technology, Yangzhou University, Yangzhou 225009, China.

Although transposon-mediated enhancer trapping (ET) is successfully applied in diverse models, the efficiency of various transposon systems varies significantly, and little information is available regarding efficiency of enhancer trapping by various transposons in zebrafish. Most potential enhancers (Ens) still lack evidence of actual En activity. Here, we compared the differences in ET efficiency between (), () and transposons. Read More

View Article
December 2018
1 Read

Cardiac and pulmonary toxicity of mesoporous silica nanoparticles is associated with excessive ROS production and redox imbalance in Wistar rats.

Biomed Pharmacother 2019 Jan 3;109:2527-2538. Epub 2018 Dec 3.

Materials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Egypt.

Mesoporous silica nanoparticles (MSNs) represent one of the most promising drug delivery systems. MSNs have attracted considerable attention in recent years both in industry and biomedicine due to their unique properties. Thus, evaluation of the toxic effects of MSNs is necessary before the biomedical and clinical applications. Read More

View Article
January 2019

α, β-Amyrin, a pentacyclic triterpenoid from Protium heptaphyllum suppresses adipocyte differentiation accompanied by down regulation of PPARγ and C/EBPα in 3T3-L1 cells.

Biomed Pharmacother 2019 Jan 26;109:1860-1866. Epub 2018 Nov 26.

Department of Physiology and Pharmacology, Natural Products Laboratory, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil. Electronic address:

Previous studies have reported the anti-obesity effects of α, β-Amyrin in high fat-fed mice. This study aimed to evaluate whether α, β-Amyrin has an anti-adipogenic effect in 3T3-L1 murine adipocytes and to explore the possible underlying mechanisms. 3T3-L1 pre-adipocytes were differentiated in a medium containing insulin, dexamethasone, and 1-methyl-3-isobutylxanthine. Read More

View Article
January 2019

Retinol palmitate and ascorbic acid: Role in oncological prevention and therapy.

Biomed Pharmacother 2019 Jan 13;109:1394-1405. Epub 2018 Nov 13.

Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City-700000, Vietnam; Department of Biological Sciences, Federal University of Piauí, Picos, Piauí, 64.067-670, Brazil. Electronic address:

Cancer development has been directly related to oxidative stress. During chemotherapy, some cancer patients use dietary antioxidants to avoid nutritional deficiencies due to cancer treatment. Among the antioxidants consumed, there are vitamins, including retinyl palmitate (PR) and ascorbic acid (AA), which have the capacity to reduce free radicals formation, protect cellular structures and maintain the cellular homeostasis. Read More

View Article
January 2019

Japanese Medical Education Reforms during the Allied Forces Occupancy; Roles Played by the Public Health and Welfare Section of the Supreme Commander for the Allied Powers.

Nihon Ishigaku Zasshi 2016 Sep;62(3):273-284

The health and welfare of the Japanese people were of a lower standard compared to other developed countries at the end of the World War II in 1945. Crawford F. Sams, Chief, the Public Health and Welfare Section of the Supreme Commander for the Allied Powers thought that medical care in a wartom country could be improved not by building new hospitals and providing more medical equipment, but through professional education and training. Read More

View Article
September 2016

Accuracy of Prenatal Diagnosis of Congenital Cardiac MalformationsAcurácia do diagnóstico pré-natal de cardiopatias congênitas.

Rev Bras Ginecol Obstet 2018 Dec 14. Epub 2018 Dec 14.

Department of Postgraduate Program and Obstetrics and Gynecology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil.

Objective:  To evaluate the accuracy of the diagnosis of fetal heart diseases obtained through ultrasound examinations performed during the prenatal period compared with the postnatal evaluation.

Methods:  A retrospective cohort study with 96 pregnant women who were attended at the Echocardiography Service and whose deliveries occurred at the Complexo Hospitalar Santa Casa de Porto Alegre, in the state of Rio Grande do Sul, Brazil. Risk factor assessment plus sensitivity and specificity analysis were used, comparing the accuracy of the screening for congenital heart disease by means of obstetrical ultrasound and morphological evaluation and fetal echocardiography, considering  < 0. Read More

View Article
December 2018

Overestimation of an outbreak of Enterobacter cloacae in a neonatal intensive care unit in Germany, 2015.

Pediatr Infect Dis J 2018 Dec 13. Epub 2018 Dec 13.

Department for Infectious Disease Epidemiology, Robert Koch-Institute, Germany.

Background: In August 2015 seventeen neonates with Enterobacter (E.) cloacae colonisation were identified in a neonatal intensive care unit (NICU) in Germany. Two developed severe brain abscesses. Read More

View Article
December 2018
1 Read

Functional, nutritional and social factors associated with mobility limitations in the elderly: a systematic review.

Salud Publica Mex 2018 Sep-Oct;60(5):579-585

Postgraduate Program in Collective Health, Odontology Department, Federal University of Rio Grande do Norte. Natal, Brazil.

Objective: To systematically review the prevalence and incidence of mobility limitations in the elderly people and their associated factors.

Materials And Methods: Articles in the electronic literature were searched via PubMed, Scopus,,Lilacs, SciELO, PAHO, MedCarib, Repidisca, Wholis, IBCES, PEDro, Medline and Bireme (2012-2016). The instrument STROBE was used to analyze the quality of the work and the PRISMA recommendation was used to structure the review. Read More

View Article
September 2017

Pre-medical majors in the humanities and social sciences: impact on communication skills and specialty choice.

Med Educ 2018 Dec 13. Epub 2018 Dec 13.

Department of Medical Education, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.

Context: Medical school admissions committees use a variety of criteria to determine which candidates to admit to their programmes. Effective communication is increasingly considered a key requisite to the practice of effective medicine. Medical students with pre-medical backgrounds in the humanities and social sciences may be more likely to acquire skills relevant to patient-centred communication, either prior to or during medical school. Read More

View Article
December 2018

Effect of cosmetic chemical preservatives on resident flora isolated from healthy facial skin.

J Cosmet Dermatol 2018 Dec 12. Epub 2018 Dec 12.

Beijing Key Lab of Plant Resources Research and Development, College of Science, Beijing Technology and Business University, Beijing, China.

Background/aims: Healthy skin harbors numerous microbes known to maintain its health and prevent attacks from external pathogens. The influence of chemical preservatives commonly used in cosmetic products on facial resident flora remains poorly characterized. In this study, we aimed to investigate the antibacterial activity of five such preservatives on in vitro cultivated skin-resident bacteria. Read More

View Article
December 2018
1 Read
1.000 Impact Factor

A study in a Polish ataxia cohort indicates genetic heterogeneity and points to MTCL1 as a novel candidate gene.

Clin Genet 2018 Dec 11. Epub 2018 Dec 11.

Department of Medical Genetics, Medical University of Warsaw, Warsaw, Poland.

Inherited ataxias are a group of highly heterogeneous, complex neurological disorders representing a significant diagnostic challenge in clinical practice. We performed next generation sequencing analysis in 10 index cases with unexplained progressive cerebellar ataxia of suspected autosomal recessive inheritance. A definite molecular diagnosis was obtained in 5/10 families and included the following diseases: autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), POLR3B-related hypomyelinating leukodystrophy, primary coenzyme Q10 deficiency type 4, Niemann-Pick disease type C1 and SYNE1-related ataxia. Read More

View Article
December 2018

Malan syndrome: Extension of genotype and phenotype spectrum.

Am J Med Genet A 2018 Dec 10. Epub 2018 Dec 10.

Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Malan syndrome and Marshall-Smith syndrome (MSS) are allelic disorders caused by mutation in NFIX gene. We report a 3-year- 6 months- old female with clinical features suggestive of Malan syndrome with mutation in exon 2 of NFIX gene. NFIX gene, where most of the mutations in Malan syndrome are located. Read More

View Article
December 2018

Morphology and Phylogeny of Calyptospora paranaidji n. sp. (Eimeriorina: Calyptosporidae), an Apicomplexan Parasite of the Hepatic Tissue of Cichla piquiti Kullander & Ferreira, 2006, From a Reservoir in the Brazilian Amazon Region.

J Eukaryot Microbiol 2018 Dec 10. Epub 2018 Dec 10.

Postgraduate Program in Biology of Infectious and Parasitic Agents /, Federal University of Pará - PPgBAIP / UFPA. Research Laboratory Carlos Azevedo / Federal Rural University of the Amazon - LPCA / UFRA, Pará, Brazil.

The coccidians of the family Calyptosporidae are parasites of the tissue and organs of fish and aquatic invertebrates, in particular in the tropical region. In contrast with other apicomplexans of the suborder Eimeriorina, the diversity and ecology of the species of the genus Calyptospora have been poorly investigated, resulting in a lacuna that restricts the understanding of the distribution and prevalence of this group of eukaryote microparasites in the Amazon region. In the present study, the integrated comparative analysis of morphological characteristics, histological and structural traits, and the sequences of a fragment of the 18S rRNA gene, provides support for the identification of a new species of Calyptospora, found parasitising the hepatic tissue of the piscivorous blue peacock bass, Cichla piquiti, captured in the reservoir of the Estreito hydroelectric dam on the middle Tocantins River in northern Brazil. Read More

View Article
December 2018
1 Read

Tuning of delta-protocadherin adhesion through combinatorial diversity.

Elife 2018 Dec 14;7. Epub 2018 Dec 14.

Department of Biomedical Sciences, Cornell University, Ithaca, United States.

The delta-protocadherins (δ-Pcdhs) play key roles in neural development, and expression studies suggest they are expressed in combination within neurons. The extent of this combinatorial diversity, and how these combinations influence cell adhesion, is poorly understood. We show that individual mouse olfactory sensory neurons express 0-7 δ-Pcdhs. Read More

View Article
December 2018

Trans-radial primary percutaneous coronary intervention in dextrocardia using double inversion technique.

J Cardiol Cases 2013 Jul 24;8(1):e31-e33. Epub 2013 Apr 24.

Department of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Percutaneous coronary intervention in patients with dextrocardia presents several challenges due to abnormal location of the heart, mirror image pattern of aortic arch and its branches, and abnormal coronary origin and orientation. The challenges involve appropriate choice of vascular access, guiding catheters, engagement technique, acquisition and interpretation of radiological orientation of coronary anatomy, and appropriate radiological angles and views. We report a patient with dextrocardia and situs inversus who presented with acute ST segment elevation myocardial infarction and was successfully treated with trans-radial primary percutaneous coronary intervention using "double inversion technique. Read More

View Article

Dracunculiasis in South Indian bonnet monkey.

Primates 2000 Jan;41(1):89-92

Department of Anatomy, Dr. Arcot Lakshmanasamy Mudaliar Postgraduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, 600 113, Chennai, India.

Dracunculiasis, popularly known as Guinea worm disease, has been eradicated from Tamil Nadu, India, and there have been no indigenous cases reported since 1981. This report describes a female bonnet monkey with dracunculiasis. She presented with fever and a blister in left hind limb. Read More

View Article
January 2000

Pediatric Thrombotic Events: Incidence, Clinical Risk Factors and Outcome.

Indian J Pediatr 2018 Dec 13. Epub 2018 Dec 13.

Department of Neonatology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India.

Objective: To study the incidence, clinical risk factors and outcome of thrombotic events in pediatric age group of 1 mo-12 y.

Methods: This prospective observational study was conducted in a tertiary care institute from September 2015 through October 2017. Forty nine children with thrombosis from 1 mo-12 y were enrolled. Read More

View Article
December 2018
1 Read

The Influence of a Xanthine-Catechin Chemical Matrix on in vitro Macrophage-Activation Triggered by Antipsychotic Ziprasidone.

Inflammation 2018 Dec 14. Epub 2018 Dec 14.

Postgraduate Program of Pharmacology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil.

Ziprasidone (ZIP) is an effective antipsychotic with low side effects than other second-generation antipsychotics. Despite this, there are reports of adverse events and previous studies associating the use of ZIP the inflammatory response. It is possible to infer that bioactive molecules present in some foods could attenuate peripheral inflammatory and oxidative stress potentially triggered ZIP. Read More

View Article
December 2018

Effect of the application of high-frequency mechanical vibration on tooth length concurrent with orthodontic treatment using clear aligners: A retrospective study.

J Orthod Sci 2018 15;7:20. Epub 2018 Nov 15.

Division of Orthodontics, School of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Objectives: To evaluate the possible change in teeth lengths as an indicator of orthodontically induced tooth root resorption (OITRR) after high-frequency mechanical vibration (HFV) treatment concurrent with Invisalign Smart Track® aligners as evaluated by cone beam computed tomography (CBCT).

Materials And Methods: The sample, composed of 30 patients with an average age of 26 ± 11 years and Class I malocclusion with an initial anterior crowding ranging from 3 to 5 mm, was divided equally into two groups; Group I received adjunctive high-frequency mechanical vibration (HFV); Group II, the control, did not receive adjunctive mechanical treatment. The maxillary incisor's teeth lengths were measured using Mimics software before (T1) and after (T2) treatment. Read More

View Article
November 2018

An Uncommon Presentation of Leiomyoma Cecum as a Subcutaneous Abscess of the Right Flank.

Cureus 2018 Oct 9;10(10):e3432. Epub 2018 Oct 9.

Otolaryngology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.

Cecal leiomyomas are rare benign tumors of smooth muscle arising from the colonic muscularis mucosa or muscularis propria. They are usually asymptomatic in nature and, if symptomatic, may present as pain in the abdomen, intestinal obstruction, or bleeding. In some cases, leiomyoma can cause free perforation leading to peritonitis. Read More

View Article
October 2018
1 Read

Weight loss as a prognostic factor for recurrence and survival in oropharyngeal squamous cell carcinoma patients.

Mol Clin Oncol 2018 Dec 5;9(6):666-672. Epub 2018 Oct 5.

Oncology Research Group, Santa Terezinha University Hospital, Joaçaba, SC 89600-000, Brazil.

Although the mortality rate of oropharyngeal squamous cell carcinoma (OPSCC) has been decreasing over the last 30 years, there has been a significant increase in the frequency of diagnosis of this type of cancer in several countries. Beyond the classic prognostic factors, such as TNM stage, there is a lack of predictive factors for recurrence and treatment response. A retrospective analysis of patients with OPSCC treated at the Oncology Department of the Santa Terezinha University Hospital between 2007 and 2012 was performed, with the aim of identifying new prognostic factors. Read More

View Article
December 2018

Study of stress-induced temporomandibular disorders among dental students: An institutional study.

Natl J Maxillofac Surg 2018 Jul-Dec;9(2):147-154

Department of Oral Medicine and Radiology, D J College of Dental Sciences and Research, Ghaziabad, Uttar Pradesh, India.

Aim And Objectives: The aim and objectives of this study are to investigate the various types of stress-inducing factors, most prevalent etiological factor and to determine the correlation between stress and temporomandibular disorders (TMDs) in Dental students in Modinagar, Ghaziabad, Uttar Pradesh.

Materials And Methods: A sample of 450 students were selected for the study divided into two groups of undergraduate (UG) and postgraduate (PG) students further subdivided into UG (1, 2, 3, and 4, interns) and PG (1, 2, 3 year). Study includes clinical evaluation of temporomandibular joint (TMJ) system (TMJ sounds, muscles of mastications, mouth opening, and range of mandibular motion) and questionnaire which covers demographic data (i. Read More

View Article
December 2018
1 Read

Diagnosis of pulmonary hypertension.

Eur Respir J 2018 Dec 13. Epub 2018 Dec 13.

Dept of Pulmonary Circulation and Cardidology, Medical Center for Postgraduate Education, ECZ-Otwock, Otwock, Poland.

A revised diagnostic algorithm provides guidelines for the diagnosis of patients with suspected pulmonary hypertension, both prior to and following referral to expert centres, and includes recommendations for expedited referral of high-risk or complicated patients and patients with confounding comorbidities. New recommendations for screening high-risk groups are given, and current diagnostic tools and emerging diagnostic technologies are reviewed. Read More

View Article
December 2018

Prediabetes Risk Evaluation Scoring System [PRESS]: A simplified scoring system for detecting undiagnosed Prediabetes.

Prim Care Diabetes 2018 Dec 10. Epub 2018 Dec 10.

Department of Community Medicine, Pt. B. D. Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India.

Objective: To develop a simplified scoring system for detecting undiagnosed prediabetes among healthy adult population of Haryana, India.

Material & Methods: This cross-sectional study was a household survey which involved 892 healthy adults >18year of age who were subjected to an oral glucose tolerance test. Sensitivity, specificity, positive and negative predictive value and area under the receiver operating characteristic (ROC) curve and the optimal cut off points for identifying undiagnosed prediabetes were calculated. Read More

View Article
December 2018

Resident Education in Laryngeal Stroboscopy and Perceptual Voice Evaluation: An Assessment.

J Voice 2018 Dec 10. Epub 2018 Dec 10.

Department of Otolaryngology-Head & Neck Surgery, University of Kansas School of Medicine, Kansas City, Kansas.

Objectives: To evaluate otolaryngology residents' level of confidence and understanding in interpreting laryngeal stroboscopy.

Methods: Otolaryngology residents from three residency programs with fellowship-trained laryngologists on faculty were invited to participate. An assessment consisting of a survey and five stroboscopic exams was administered. Read More

View Article
December 2018

Embedding sports and exercise medicine into the medical curriculum; a call for inclusion.

BMC Med Educ 2018 Dec 13;18(1):306. Epub 2018 Dec 13.

University of Sheffield Medical School, University of Sheffield, Sheffield, UK.

The UK is currently facing an inactivity crises, with 1 in 5 children currently meeting physical activity guidelines (Health Survey for England, Children's Health, 2016). To combat this growing problem there has been increased interest in promoting exercise and healthy lifestyle advise to patients as a method for improving public health. In line with this, the specialty of Sports and Exercise Medicine (SEM) has been gaining momentum and is now a recognised specialty with a higher specialist training programme. Read More

View Article
December 2018

Fucoidan Exerts Anticancer Effects Against Head and Neck Squamous Cell Carcinoma In Vitro.

Molecules 2018 Dec 12;23(12). Epub 2018 Dec 12.

Radiobiology Lab, The Greater Poland Cancer Centre, Garbary 15 Str., 61-866 Poznan, Poland.

Fucoidans have been reported to exert anticancer effects with simultaneous low toxicity against healthy tissue. That correlation was observed in several cancer models, however, it has never been investigated in head and neck cancer before. To magnify the efficacy of conventional therapy, the administration of agents like fucoidan could be beneficial. Read More

View Article
December 2018
1 Read

Synthesis and Preparation of Chitosan/Clay Microspheres: Effect of Process Parameters and Clay Type.

Materials (Basel) 2018 Dec 12;11(12). Epub 2018 Dec 12.

Department of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.

This work aimed to prepare chitosan/clay microspheres, by the precipitation method, for use in drug carrier systems. The influence of the process parameters, particularly two airflows of the drag system (2.5 and 10 L·min) on the microspheres physical dimensions and properties, such as microstructure, degree of swelling and porosity were evaluated. Read More

View Article
December 2018

Acute Toxicity of the Recombinant and Native Phα1β Toxin: New Analgesic from Spider Venom.

Toxins (Basel) 2018 Dec 12;10(12). Epub 2018 Dec 12.

Postgraduate Program in Genetics and Applied Toxicology, Lutheran University of Brazil, Canoas, RS 92425⁻900, Brazil.

Phα1β, a purified peptide from the venom of the spider , and its recombinant form CTK 01512-2 are voltage-dependent calcium channel (Ca) blockers of types N, R, /Q, and L with a preference for type N. These peptides show analgesic action in different pain models in rats. The aim of this study was to evaluate the acute intrathecal toxicity of the native and recombinant Phα1β toxin in Wistar rats. Read More

View Article
December 2018
2 Reads

Facile Fabrication of Amorphous Photonic Structures with Non-Iridescent and Highly-Stable Structural Color on Textile Substrates.

Materials (Basel) 2018 Dec 8;11(12). Epub 2018 Dec 8.

Engineering Research Center for Eco-Dyeing and Finishing of Textiles, Ministry of Education, Zhejiang Sci-Tech University, Hangzhou 310018, China.

Amorphous photonic structures with non-iridescent and highly-stable structural color were fabricated via a simple one-step spray-coating technique. With this strategy, the obtained films on textile substrates presented short-ordered and amorphous photonic structures (APSs) similar to the amorphous nanostructures of avian feathers. The structural color presented the same hue when viewed at different angles and could be well controlled by varying the diameters of the SiO₂ nanospheres. Read More

View Article
December 2018

Intakes of Zinc, Potassium, Calcium, and Magnesium of Individuals with Type 2 Diabetes Mellitus and the Relationship with Glycemic Control.

Nutrients 2018 Dec 8;10(12). Epub 2018 Dec 8.

Nutrition Sciences Postgraduate Program, Department of Nutrition, Federal University of Sergipe, Avenida Marechal Rondon, S/N, Jardim Rosa Elze, São Cristovão, 49100-000 Sergipe, Brazil.

The role of the concomitant intake of zinc, potassium, calcium, and magnesium in the glycemic control of individuals with type 2 diabetes mellitus (T2DM) has not been extensively discussed. We evaluated the relationship between the dietary intake of these micronutrients and glycemic markers in 95 individuals with T2DM (mean age 48.6 ± 8. Read More

View Article
December 2018

Non-Contact, Simple Neonatal Monitoring by Photoplethysmography.

Sensors (Basel) 2018 Dec 10;18(12). Epub 2018 Dec 10.

Neonatology, San Carlos Clinical Hospital, Madrid 28040, Spain.

This paper presents non-contact vital sign monitoring in neonates, based on image processing, where a standard color camera captures the plethysmographic signal and the heart and breathing rates are processed and estimated online. It is important that the measurements are taken in a non-invasive manner, which is imperceptible to the patient. Currently, many methods have been proposed for non-contact measurement. Read More

View Article
December 2018

Vision-Based Apple Classification for Smart Manufacturing.

Sensors (Basel) 2018 Dec 10;18(12). Epub 2018 Dec 10.

Department of Computer System and Technology, Faculty of Computer Science and Information Technology, University of Malaya, 50603 Kuala Lumpur, Malaysia.

Smart manufacturing enables an efficient manufacturing process by optimizing production and product transaction. The optimization is performed through data analytics that requires reliable and informative data as input. Therefore, in this paper, an accurate data capture approach based on a vision sensor is proposed. Read More

View Article
December 2018

Biological Aggressiveness of Subclinical No-Mass Ductal Carcinoma In Situ (DCIS) Can Be Reflected by the Expression Profiles of Epithelial-Mesenchymal Transition Triggers.

Int J Mol Sci 2018 Dec 7;19(12). Epub 2018 Dec 7.

Breast Unit, Department of Surgical Oncology, Lower Silesia Oncology Center, 53-413 Wroclaw, Poland.

Epithelial-mesenchymal transitions (EMTs) have been recently implicated in the process of cancer progression. The aim of this study was to assess how the preoperative expression patterns of EMT biomarkers correlate with the risk of postoperative invasion in ductal carcinoma in situ (DCIS) found on stereotactic breast biopsies. N-cadherin, Snail1, and secreted protein acidic and rich in cysteine (SPARC) immunoreactivity was observed in 8%, 62%, and 38% of tumors, respectively. Read More

View Article
December 2018

Kidney injury following envenoming by hump-nosed pit viper (Genus: Hypnale) in Sri Lanka: proven and probable cases.

Trans R Soc Trop Med Hyg 2018 Dec 13. Epub 2018 Dec 13.

Department of Medicine, Faculty of Medicine, University of Peradeniya, Sri Lanka.

Background: Hump-nosed pit vipers (Hypnale hypnale) are highly venomous snakes found in Sri Lanka and the Western Ghats region of India. They are the most common cause of venomous snakebites in Sri Lanka, mainly causing local envenoming leading to pain, swelling and necrosis. Systemic envenoming causing acute kidney injury and coagulopathy are more commonly recognized following their bites. Read More

View Article
December 2018
1 Read

Deletion 7q21.2-q22.1 in a case with split hand-split foot malformation, sensorineural hearing loss and intellectual disability: Phenotype subtypes and the correlation with genotypes.

Eur J Med Genet 2018 Dec 10. Epub 2018 Dec 10.

Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, 226014, Uttar Pradesh, India. Electronic address:

The split hand/split foot malformation (SHFM) or ectrodactyly is a rare congenital heterogeneous limb developmental disorder with at least 6 associated loci. It is characterized by absence of central rays of hands and feet and fusion of remaining digits. It can present as an isolated malformation or in combination with additional anomalies (non-syndromic or syndromic ectrodactyly). Read More

View Article
December 2018

Insights from the 11th International Congress on Autoimmunity, Lisbon, Portugal, 2018.

Clin Immunol 2018 Dec 10. Epub 2018 Dec 10.

Zabludowicz Center for Autoimmune Diseases, Tel-Aviv University, Israel.; Sackler Faculty of Medicine, Tel-Aviv University, Israel.

View Article
December 2018

ST Segment-Elevation Myocardial Ischemia After Arterial Switch Operation Due to Pericardial Drain Placement: A Case Report.

A A Pract 2018 Dec 7. Epub 2018 Dec 7.

From the Department of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Myocardial ischemia postarterial switch operation has been reported extensively in the literature and has been almost exclusively ascribed to issues related to coronary artery translocation. Here, we report a case of a 5-week-old child with D-transposition of the great arteries who underwent an arterial switch operation and developed myocardial ischemia after pericardial drain placement, as evidenced by significant ST segment elevation and abnormal regional cardiac wall motion. The ST segment and cardiac wall motion improved once the drain was withdrawn from the pericardium and placed in the retrosternal space. Read More

View Article
December 2018

Recent Advancement against Neglected Diseases.

Curr Top Med Chem 2018 ;18(18):1520-1521

Department of Biochemistry/Bioinformatics Institute of Science GITAM University, Visakhapatnam, A.P, India.

View Article
January 2018

Epidemiology of hepatitis B and C viral infections in Ladakh region.

Indian J Gastroenterol 2018 Dec 12. Epub 2018 Dec 12.

Department of Gastroenterology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, 190 011, India.

Background: Little is known about the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in Ladakh, a mountainous region with low population density. We, therefore, determined these and tried to identify risk factors associated with these infections.

Methods: Randomly selected residents of Ladakh region were tested for hepatitis B surface antigen (HBsAg), antibodies to hepatitis B core antigen (anti-HBc) and antibodies to HCV (anti-HCV). Read More

View Article
December 2018

Intrauterine fetal MR versus postmortem MR imaging after therapeutic termination of pregnancy: evaluation of the concordance in the detection of brain abnormalities at early gestational stage.

Eur Radiol 2018 Dec 12. Epub 2018 Dec 12.

Pediatric Radiology and Neuroradiology Department, Children's Hospital V. Buzzi - ASST Fatebenefratelli-Sacco, Via Castelvetro 32, 20154, Milan, Italy.

Background And Purpose: Fetal postmortem MR Imaging (pmMRI) has been recently used as an adjuvant tool to conventional brain autopsy after termination of pregnancy (TOP). Our purpose was to compare the diagnostic performance of intrauterine MRI (iuMRI) and pmMRI in the detection of brain anomalies in fetuses at early gestational age (GA).

Material And Methods: We retrospectively collected 53 fetuses who had undergone iuMRI and pmMRI for suspected brain anomalies. Read More

View Article
December 2018

An IRT-Multiple Indicators Multiple Causes (MIMIC) Approach as a Method of Examining Item Response Latency.

Front Psychol 2018 13;9:2177. Epub 2018 Nov 13.

Psychology Department, College of Education, King Saud University, Riyadh, Saudi Arabia.

The analysis of response time has received increasing attention during the last decades, since evidence from several studies supported the argument that there is a direct relationship between item response time and test performance. The aim of this study was to investigate whether item response latency affects person's ability parameters, in that it represents an adaptive or maladaptive practice. To examine the above research question data from 8,475 individuals completing the computerized version of the Postgraduate General Aptitude Test (PAGAT) were analyzed. Read More

View Article
November 2018

Profile of pterostilbene-induced redox homeostasis modulation in cardiac myoblasts and heart tissue.

J Biosci 2018 Dec;43(5):931-940

Postgraduate Program in Pharmacology and Therapeutics, Department of Physiology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.

This study was designed to investigate the effect of pterostilbene (PTS) on cardiac oxidative stress in vitro, as this is a simple and promising methodology to study cardiac disease. Cardiac myoblasts (H9c2 cells) and homogenised cardiac tissue were incubated with the PTS and cyclodextrin (PTS + HPβCD) complex for 1 and 24 h, respectively, at concentrations of 50μM for the cells and 25 and 50μM for cardiac tissue. The PTS + HPβCD complex was used to increase the solubility of PTS in water. Read More

View Article
December 2018

A two-stage spatial allocation model for elderly healthcare facilities in large-scale affordable housing communities: a case study in Nanjing City.

Int J Equity Health 2018 Dec 12;17(1):183. Epub 2018 Dec 12.

School of Civil Engineering, Southeast University, Jiangning District, Nanjing, 211189, China.

Background: As the proportion of elderly residents living in large-scale affordable housing communities (LAHCs) increases in China, serious problems have become apparent related to the spatial allocation of elderly healthcare facilities (EHFs), e.g., insufficient provision and inaccessibility. Read More

View Article
December 2018

The Prevalence of Lymphatic Filariasis in Elementary School Children Living in Endemic Areas: A Baseline Survey Prior to Mass Drug Administration in Pekalongan District-Indonesia.

Iran J Public Health 2018 Oct;47(10):1484-1492

Dept. of Parasitology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.

Background: WHO initiated lymphatic filariasis (LF) elimination globally. Pekalongan District, as LF endemic area, started a program of mass drug administration (MDA) to combat LF in 2015. This study aimed to determine prevalence of infection prior to the MDA. Read More

View Article
October 2018

Complications of Decompressive Craniectomy.

Front Neurol 2018 20;9:977. Epub 2018 Nov 20.

Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India.

Decompressive craniectomy (DC) has become the definitive surgical procedure to manage medically intractable rise in intracranial pressure due to stroke and traumatic brain injury. With incoming evidence from recent multi-centric randomized controlled trials to support its use, we could expect a significant rise in the number of patients who undergo this procedure. Although one would argue that the procedure reduces mortality only at the expense of increasing the proportion of the severely disabled, what is not contested is that patients face the risk of a large number of complications after the operation and that can further compromise the quality of life. Read More

View Article
November 2018