Search Our Scientific Publications & Authors

Ann R Coll Surg Engl 2021 Apr 4;103(4):e114-e115. Epub 2021 Mar 4.

Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, UK.

Neuropathic bladder may be a co-associated morbidity in newborn babies following resection of a sacrococcygeal teratoma. We report a case of a male newborn showing features of incomplete urinary voiding requiring intermittent catheterisation after operation for bladder emptying. Videourodynamic assessment excluded neuropathic bladder and posterior urethral valves were demonstrated on micturating cystography. Read More

J Endourol Case Rep 2020 29;6(4):362-365. Epub 2020 Dec 29.

Department of Radiodiagnosis, DODA Imaging, Pusa Road, New Delhi, India.

Multiple urethral anomalies are rare with its own challenges in diagnosis and management. The double urethral obstructions are often missed as proximal obstruction can mask the early diagnosis of distal obstruction. We present a rare case of concomitant posterior urethral valve (PUV) and anterior urethral valve (AUV) with a large anterior urethral diverticula (AUD) and hypospadias. Read More

J Pediatr Urol 2021 Feb 4;17(1):101.e1-101.e9. Epub 2020 Nov 4.

Department of Radiodiagnosis, DODA Imaging, PUSA Road, New Delhi, India.

Background: Anterior urethral valve (AUV) and anterior urethral diverticulum (AUD) are two rare causes of anterior urethral obstruction with variable presentation and anatomy. Their existence as the same or different entity is still debatable, and management has not yet been standardized.

Objective: This study is a retrospective review of cases diagnosed with anterior urethral obstruction and correlation of radiological and endoscopic anatomy of AUV and AUD. Read More

Pediatr Neurosurg 2020 7;55(4):210-214. Epub 2020 Sep 7.

Department of Histopathology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Introduction: Cavernous malformation (CM) of the pediatric spine is uncommon, and its presentation especially in infancy is extremely rare. We report an unusual case of thoracolumbar intramedullary CM with hemorrhage in a 5-month-old male child.

Case Presentation: The child presented with the predominant symptom of urinary retention, and the underlying neurological cause was initially overlooked. Read More

Saudi Med J 2020 Sep;41(9):1011-1014

Male Genital Reconstruction/Sexual Medicine & Minimal invasive Urology, College of Medicine, Taibah University, Madinah, Kingdom of Saudi Arabia. E-mail.

Posterior urethral valves (PUVs) are frequently recognized during the perinatal period. Delayed diagnosis is reported usually within the first decade of life with diverse clinical presentations. In the current case report, we describe a 45 years old man patient who presented with aspermia and primary infertility for 8 years in whom his diagnostic workup revealed radiological imaging suggestive of PUVs. Read More

J Pediatr Urol 2020 10 4;16(5):585.e1-585.e7. Epub 2020 Apr 4.

Department of Surgery, Texas Children's Hospital, USA; Scott Department of Urology, Baylor College of Medicine, USA.

Background: Anterior urethral valves (AUV) and associated anterior urethral diverticula (AUD) are a rare cause of congenital lower urinary tract obstruction. They occur 25-30 times less frequently than posterior urethral valves (PUV) and historically tend to have a less aggressive presentation and outcome. However, due to the low incidence, little is known about management and long-term prognosis. Read More

Niger Med J 2019 Nov-Dec;60(6):306-311. Epub 2020 Feb 24.

Department of Surgery, Division of Paediatric Surgery, University of Ilorin/University of Ilorin Teaching Hospital, Ilorin, Nigeria.

Background: Posterior urethral valve (PUV) is a significant cause of morbidity and mortality among male children resulting in renal failure in 25%-30% before adolescence irrespective of initial treatment. This study aimed at evaluating the early outcomes of children managed for PUV.

Materials And Methods: This was a prospective study of all children who were treated for PUV between 2012 and 2016 at a single referral institution. Read More

Cir Pediatr 2020 Jan 20;33(1):36-42. Epub 2020 Jan 20.

Radiologic Department's. Complejo Hospitalario Universitario de Albacete. Albacete (Spain).

Objectives: Report our experience with the use of contrast-enhanced serial voiding urosonography (SVU) for posterior urethral valve (PUV) patient diagnosis and management.

Material And Methods: Descriptive retrospective study in 0- to 14-year-old patients with suspected PUV at SVU performed as a first contrast-enhanced urinary tract test with subsequent cystoscopic study. Variables were analyzed using SPSSv22. Read More

Pediatr Radiol 2020 04 9;50(4):575-582. Epub 2019 Nov 9.

Service de Radiologie, Hôpital d'Enfants Armand-Trousseau APHP, Sorbonne Université, Paris, France.

A wide range of genitourinary pathologies can be diagnosed in utero, from a simple vesicoureteral reflux to a more complex disorder of sexual differentiation. The prognosis and neonatal management of these conditions differ significantly. Evaluation of the fetal perineal anatomy is paramount to making the right diagnosis. Read More

Ethiop J Health Sci 2019 Sep;29(5):591-596

Department of Radiology, School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia.

Background: Most congenital anomalies of the urinary tract present with hydronephrosis. Some are physiological while others pathological. Ultrasound, micturating cyst urethrography, dynamic renal scintigraphy, intravenous urography, dynamic and static magnetic resonance urography are used for examination. Read More

BMJ Case Rep 2019 Jul 23;12(7). Epub 2019 Jul 23.

Paediatric Urology, Evelina London Children's Healthcare, London, UK.

We present a rare case of association of anterior rectal duplication and posterior urethral valve (PUV). A term neonate with no antenatal concerns was admitted with urosepsis and acute renal injury at 18 days of age. History revealed a poor urinary stream and dribbling. Read More

J Pediatr Urol 2019 Aug 4;15(4):379.e1-379.e8. Epub 2019 Apr 4.

Urology and Nephrology Research Center, Department of Urology, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Neuropathic bladder, voiding dysfunction, and posterior urethral valves may cause a great challenge in children. Preserving the kidney function is the main aim in all of these patients which can be achieved by cutaneous vesicostomy.

Objective: The objective of this study is to evaluate the long-term outcomes of patients who have undergone cutaneous vesicostomy in an 11-year period at the study center. Read More

Ultrasound Obstet Gynecol 2020 Jul;56(1):86-95

EA 7328-PACT, Paris Descartes University, Sorbonne Paris Cité, Imagine Institue, Paris, France.

Objectives: Incompatibility between currently available fetoscopes and the anatomical constraints of the distended fetal bladder, with the resulting curvature around the bladder neck, account for most technical difficulties during fetal cystoscopy in lower urinary tract obstruction (LUTO). The aim of this anatomical study was to assess by magnetic resonance imaging (MRI) the variation in three bladder angles (bladder-neck angle (BNA), vesicourethral angle (VUA) and angle between bladder dome and posterior urethra (DUA)), according to gestational age (GA), bladder volume and the presence of LUTO.

Methods: From our fetal medicine database, we retrieved for review 46 MRI examinations of male fetuses between 2015 and 2019, including 17 with LUTO, examined at a mean GA of 28. Read More

Pediatr Int 2018 Dec;60(12):1090-1091

Department of Urology, Keio University School of Medicine, Tokyo, Japan.

BMJ Case Rep 2018 Sep 23;2018. Epub 2018 Sep 23.

Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Posterior urethral valve and foreign body are among the important causes of male urethral obstruction. Although one is congenital and the other is acquired, both entities are rare in children with only a few reported cases. Because of myriad of symptoms associated with both conditions, a conclusive diagnosis requires both physical examination and radiological imaging. Read More

Prog Urol 2018 Oct 3;28(12):596-602. Epub 2018 Jul 3.

Chirurgie viscérale infantile, hôpital Brabois Enfants, CHU de Nancy, rue du Morvan, 54511 Vandœuvre-lès-Nancy cedex, France.

Introduction: Congenital Lower Urinary Tract Obstructions (LUTO) is a heterogeneous group of diseases in which urine elimination is obstructed at the level of bladder neck or urethra. The aim of the study is to evaluate the long-term renal outcome of patients suffering of congenital LUTO.

Patients And Method: We retrospectively reviewed patients with congenital LUTO. Read More

BMC Urol 2018 May 21;18(1):46. Epub 2018 May 21.

Departmennt of Surgery and Subspecialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.

Background: The incidence of posterior urethral valve (PUV) is estimated at 1:5000-1:8000 males. It is the most common paediatric urologic urgency and the most common cause of male obstructive uropathy and chronic renal failure in children. The study aimed to describe the experience of Yaoundé gynaeco-obstetrics and paediatric hospital in the management of PUV. Read More

Curr Urol Rep 2018 May 17;19(7):55. Epub 2018 May 17.

Division of Urology, Children's Hospital of Philadelphia, 3rd Floor Wood Center, 3401 Civic Center Boulevard, Philadelphia, PA, 19104, USA.

Purpose Of Review: The purpose of this review is to bring the reader up to date on the current risk factors for the development of renal deterioration in the boys with posterior urethral valves (PUV) and approaches to modify this risk.

Recent Findings: Renal bladder ultrasound (RBUS) is routinely performed in boys with PUV and recent advancements allow imaging processing that can more accurately quantify renal parenchyma and correlate this with risk for renal loss. Refinement of urine studies may improve our ability to stratify patients into renal loss categories. Read More

J Obstet Gynaecol Res 2018 Jul 19;44(7):1318-1321. Epub 2018 Apr 19.

Department of Obstetrics and Gynecology, Mie University Faculty Medicine, Mie, Japan.

Posterior urethral valve (PUV) rarely causes bladder rupture. We experienced hydronephrosis due to ureteral obstruction after the natural repair of a ruptured bladder in a fetus with PUV. Fetal ascites and oligohydramnios were diagnosed at 26 weeks' gestational age. Read More

Abdom Radiol (NY) 2018 09;43(9):2517-2518

Diagnostic Imaging Department, Hospital Israelita Albert Einstein, Av. Albert Einstein, 627, São Paulo, 05652-901, Brazil.

Fukushima J Med Sci 2017 Aug 26;63(2):116-120. Epub 2017 Jul 26.

Division of Neonatology, Tokyo Metropolitan Hachioji Children's Hospital.

The patient was a male infant with an antenatal diagnosis of huge intraabdominal mass. Prenatal ultrasound at 35 weeks gestation revealed a markedly enlarged cystic mass in the lower abdomen. After birth at 38 weeks, the infant was allowed to void spontaneously and passed meconium. Read More

Investig Clin Urol 2017 06 7;58(Suppl 1):S46-S53. Epub 2017 Jun 7.

Department of Pediatric Urology, Jichi Medical University Children's Medical Center Tochigi, Shimotsuke, Japan.

Vesicoureteral reflux (VUR) is one of the most common diseases in pediatric urology and classified into primary and secondary VUR. Although posterior urethral valve (PUV) is well known as a cause of the secondary VUR, it is controversial that minor urethral deformity recognized in voiding cystourethrography represents mild end of PUV spectrum and contributes to the secondary VUR. We have been studying for these ten years congenital urethral obstructive lesions with special attention to its urethrographic and endoscopic morphology as well as therapeutic response with transurethral incision. Read More

J Pediatr Urol 2017 Oct 14;13(5):486.e1-486.e10. Epub 2017 Apr 14.

Department of Obstetrics and Gynecology, Fetal Diagnosis and Therapy Unit, Catholic University of Sacred Heart, Policlinico A. Gemelli Hospital, Rome, Italy.

Introduction: Megacystis is a condition of abnormal enlarged fetal bladder for gestational age, which is usually associated with urological malformations that may constitute a life-threatening condition for the baby.

Objective: The purpose of this study was to assess the prognostic and etiological criteria of fetal megacystis and to describe the neonatal outcome in a large series collected in a single tertiary center.

Study Design: A retrospective observational study was conducted between 2008 and 2012. Read More

J Am Coll Radiol 2017 May;14(5S):S362-S371

Specialty Chair, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Urinary tract infection (UTI) is common in young children and may cause pyelonephritis and renal scarring. Long-term complications from renal scarring are low. The role of imaging is to evaluate for underlying urologic abnormalities and guide treatment. Read More

Z Geburtshilfe Neonatol 2017 Apr 9;221(2):88-91. Epub 2017 Mar 9.

Division of Neonatology and Pediatric Intensive Care Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg.

A 34-year-old para V woman was referred to our centre at 35+1 weeks of gestation for an assumed fetal malformation with prenatal renal impairment and anhydramnios. Prenatal ultrasound demonstrated unilateral renal agenesis; the bladder was not detectable. The baby was born by caesarian section at 36+2 weeks of gestation because of placental insufficiency. Read More

World J Urol 2017 Oct 28;35(10):1611-1616. Epub 2017 Feb 28.

Department of Pediatric Urology, Jichi Medical University, Children's Medical Center Tochigi, 3311-1, Yakushiji Shimotsuke-shi, Tochigi, 329-0498, Japan.

Purpose: Endoscopic transurethral incision (TUI) of posterior urethral valve (PUV) can improve daytime urinary incontinence (DUI) and nocturnal enuresis (NE). However, the underlying mechanism has not been elucidated. In this study, we retrospectively examined the mobility of the urethra before and after TUI by measuring the urethral angle with voiding cystourethrography (VCUG), to clarify the effects of TUI on the morphology of the urethra during voiding. Read More

Pediatr Nephrol 2017 Aug 22;32(8):1391-1400. Epub 2017 Feb 22.

Interdisciplinary Laboratory of Medical Investigation, Faculty of Medicine, Universidade Federal de Minas Gerais (UFMG), Avenida Alfredo Balena, 190, 2° andar, sala 281, 30.130-100, Belo Horizonte, MG, Brazil.

Background: The aim of this cross-sectional study was to investigate inflammatory biomarkers in urine samples of 24 fetuses with posterior urethral valve (PUV) collected at 22 ± 4 weeks of gestation and to compare the findings with measurements in urine samples of 22 male healthy preterm neonates at 23 ± 4 weeks (control group).

Methods: Inflammatory biomarkers in urine were measured using a cytometric bead array [interleukin (IL)-2, IL-4, IL-6, IL-10, interferon (IFN)-γ, soluable tumor necrosis factor receptor (TNFR) 1, sTNFR2, monocyte chemoattractant protein-1/chemokine ligand 2 (MCP-1/CCL2), eotaxin/CCL11 and interferon gamma-induced protein/10/C-X-C motif chemokine 10 (IP-10/CXCL10)] and ELISA assays [TNF, IL-8/CXCL8 and transforming growth factor-beta (TGF-β)]. The Mann-Whitney test was used to compare medians. Read More

J Pediatr Urol 2017 Jun 12;13(3):265.e1-265.e6. Epub 2017 Jan 12.

Department of Paediatric Surgery, Birmingham Children's Hospital NHS Trust, Steelhouse Lane, Birmingham, B46NH, United Kingdom. Electronic address:

Objective: Radiological bladder abnormalities in boys with posterior urethral valves (PUV) are well recognised; however, the assessment is subjective. The shape, wall, reflux and diverticuli (SWRD) score objectively assesses shape, wall, reflux and diverticuli in a simple way. This study was undertaken to demonstrate that the SWRD score is reliable, reproducible and correlates with bladder outcome and videourodynamic (VUD) assessment in boys with PUV. Read More

Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2016 Nov;37(2-3):107-113

Regular ultrasound examinations carried out in the second trimester of pregnancy help in detecting many anomalies in the fetal urinary tract. Their percentage ranges from 1% to 3% of all controlled pregnancies. There is a wide spectrum of anomalies that affect the urinary tract, but the most significant are: uretero/hydronephrosis (unilateral or bilateral), kidney agenesis, dysplastic kidney, polycystic and multicystic kidneys, anomalies of ascent, anomalies of kidney rotation or fusion, bladder exstrophy, posterior urethra valve etc. Read More

Med Ultrason 2016 Sep;18(3):400-2

Department of Surgery, Ganesh Das Hospital, Shillong, Meghalaya, India.

Urinary retention in young children and infancy is relatively rare. The commonest malignancy cause of bladder outlet obstruction in infancy is prostatic rhabdomyosarcoma; the commonest cause of congenital bladder outlet obstruction in a male infantis posterior urethral valve and the commonest cause of urethral obstruction in male children is urethral calculi. We present here a report on three cases of urethral obstruction in male children. Read More