Search Our Scientific Publications & Authors

World Neurosurg 2018 Dec 8. Epub 2018 Dec 8.

Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address:

Large, broad-based basilar artery (BA) apex aneurysms involving multiple arterial origins are complex lesions commonly not amenable to direct clipping or endovascular management. BA proximal (Hunterian) occlusion with extracranial-to-intracranial bypass is a supported strategy if one or both posterior communicating arteries are small. Hunterian ligation risks sudden aneurysm thrombosis and thromboembolism in the perforator rich BA apex. Read More

Prog Retin Eye Res 2018 Dec 8. Epub 2018 Dec 8.

Department of Ophthalmology, Medical Faculty Mannheim, Ruprecht-Karls-University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. Electronic address:

A posterior staphyloma is an outpouching of a circumscribed region of the posterior fundus and has been considered a hallmark of pathologic myopia. Occurring in highly myopic eyes, it is histologically characterized by a relatively abrupt scleral thinning starting at the staphyloma edge, a pronounced de-arrangement of scleral collagen fibrils and a marked choroidal thinning, which is the most marked at the staphyloma edge and which occurs in addition to the axial elongation-associated choroidal thinning. Besides in highly myopic eyes, a posterior staphyloma can be found in non-highly myopic eyes in association with retinitis pigmentosa or localized defects of Bruch's membrane in the cases of which it is not associated with a marked choroidal thinning. Read More

Biom J 2018 Dec 10. Epub 2018 Dec 10.

Department of Mathematical Sciences and Biocenter Oulu, University of Oulu, Oulu, Finland.

Stochastic search variable selection (SSVS) is a Bayesian variable selection method that employs covariate-specific discrete indicator variables to select which covariates (e.g., molecular markers) are included in or excluded from the model. Read More

J Orthop Res 2018 Dec 11. Epub 2018 Dec 11.

RR&D Center for Limb Loss and MoBility, VA Puget Sound, Seattle, WA.

Foot type has been associated with pain, injury, and altered gait mechanics. Morphological variations in foot bones due to foot type variation may impact surgical and therapeutic treatments. The purpose of this study was to utilize principal component analysis (PCA) to determine how morphology of the hind- and midfoot bones differs among foot types and sex. Read More

Am J Med Genet A 2018 Nov;176(11):2234-2235

J Orthop Res 2018 Dec 11. Epub 2018 Dec 11.

Clinic of Orthopaedics and Sportsorthopaedics, Klinikum rd. Isar, Technische Universität München, Munich, Germany.

(1) Can iliosacral osseous corridor diameters in sacral dysmorphism be enlarged by in-out-in screw placement at the posterior iliosacral recessus? (2) Are lumbosacral transitional vertebra (LSTV) the anatomical cause for sacral dysmorphism? (3) Are there sex-specific differences in sacral dysmorphism? 594 multislice CT scans were screened for sacral dysmorphism and 55 data-sets selected. Each pelvis was segmented manually and cylindrical iliosacral corridors (S1 and S2 vertebra) were semi-automatically determined. Corridor trajectories, -diameters and -lengths were measured. Read More

Cochrane Database Syst Rev 2018 Dec 8;12:CD009195. Epub 2018 Dec 8.

Department of Medical Imaging, Gold Coast University Hospital, 1 Hospital Blvd, Southport, Queensland, Australia, 4215.

Background: Chronic limb-threatening ischaemia (CLTI) is a manifestation of peripheral arterial disease (PAD) that includes chronic ischaemic rest pain or ischaemic skin lesions, ulcers, or gangrene for longer than two weeks. The severity of the disease depends on the extent of arterial stenosis and the availability of collateral circulation. Treatment for CLTI aims to relieve ischaemic pain, heal ischaemic ulcers, prevent limb loss, improve quality of life, and prolong survival. Read More

Anat Rec (Hoboken) 2018 Dec 8. Epub 2018 Dec 8.

CR2P UMR 7207 (MNHN, CNRS, UPMC, Sorbonne Université), Département Origines et Evolution, Muséum National d'Histoire naturelle, CP 48, 57 rue Cuvier, F-75231 Paris cedex 05, France.

Sharks of Late Paleozoic oceans evolved unique dentitions for catching and eating soft bodied prey. A diverse but poorly preserved clade, edestoids are noted for developing biting teeth at the midline of their jaws. Helicoprion has a continuously growing root to accommodate more than 100 crowns that spiraled on top of one another to form a symphyseal whorl supported and laterally braced within the lower jaw. Read More

J Anat 2018 Dec 9. Epub 2018 Dec 9.

Fraunhofer Institute for Machine Tools and Forming Technology IWU, Dresden, Germany.

The sacroiliac joint (SIJ) is a well-known source of low back and pelvic pain, of increasing interest for both conservative and surgical treatment. Alterations in the kinematics of the pelvis have been hypothesized as a major cause of SIJ-related pain. However, definitions of both the range and the extent of physiological movement are controversial, and there are no clear baseline data for pathological alterations. Read More

Mov Disord 2018 Dec 10. Epub 2018 Dec 10.

Movement Disorders Unit, Neurology Department, Sant Pau Hospital, Barcelona, Spain.

Background: Minor hallucinations and well-structured hallucinations are considered in the severity continuum of the psychotic spectrum associated with Parkinson's disease. Although their chronological relationship is largely unknown, the spatial patterns of brain atrophy in these 2 forms of hallucinations partially overlap, suggesting they share similar pathophysiological processes. Functional connectivity studies show that disruption of functional networks involved in perception and attention could be relevant in the emergence of well-structured hallucinations. Read More

Folia Morphol (Warsz) 2018 Dec 11. Epub 2018 Dec 11.

The pneumatization of the articular tubercle (PAT) of the temporal squama is a rare condition that modifies the barrier between the temporomandibular joint (TMJ) space and the middle cranial fossa. During a routine examination of the cone beam computed tomography (CBCT) files of patients who were scanned for dental medical purposes, we identified a case with multiple rare anatomic variations. First, the petrous apex was bilaterally pneumatized. Read More

Musculoskelet Surg 2018 Dec 10. Epub 2018 Dec 10.

S.C. Ortopedia e Traumatologia, IRCCS Policlinico San Matteo, Università degli Studi di Pavia, Viale Camillo Golgi 19, 27100, Pavia, PV, Italy.

Background: Low back pain and sciatica represent a common disabling condition with a significant impact on the social, working and economic lives of patients. Transforaminal lumbar interbody fusion (TLIF) is a surgical procedure used in degenerative spine conditions. Several types of cages were used in the TLIF procedure. Read More

Ir J Med Sci 2018 Dec 8. Epub 2018 Dec 8.

Health Information and Quality Authority, George's Court, George's Lane, Dublin, D07 E98Y, Ireland.

Purpose: Although good evidence exists regarding the clinical effectiveness of mechanical thrombectomy for people with acute ischaemic stroke, cost-effectiveness should also be considered. The aim of this study was to systematically review the evidence of cost-effectiveness of emergency endovascular therapy using mechanical thrombectomy in the management of acute ischaemic stroke.

Methods: The search was carried out in PubMed, EMBASE, Cochrane Library, and a grey literature search. Read More

Curr Med Sci 2018 Dec 7;38(6):1090-1095. Epub 2018 Dec 7.

Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

This study is aimed to explore the clinical application of the guiding template designed by three-dimensional printing data for the insertion of sacroiliac screws. A retrospective study of 7 cases (from July 2016 to December 2016), in which the guiding template printed by the threedimensional printing technique was used for the insertion of sacroiliac screws of patients with posterior ring injuries of pelvis, was performed. Totally, 4 males and 3 females were included in template group, aged from 38 to 65 years old (mean 50. Read More

Childs Nerv Syst 2018 Dec 10. Epub 2018 Dec 10.

Department of Neurosurgery, Baylor College of Medicine, Division of Pediatric Neurosurgery, Texas Children's Hospital, Houston, TX, USA.

Introduction: Chiari malformation type 1 (CM-1) is a common congenital or acquired malformation of the posterior fossa. We aimed to characterize preoperative risk factors, perioperative complications, and postoperative outcomes related to CM-1 surgery in pediatric populations across a nationwide network of pediatric hospitals in the United States (US).

Methods: The Children's Hospital Association's Pediatric Health Information System (PHIS) database was used to examine patients < 21 years old in the US-based nationwide database who underwent inpatient surgery for CM-1 from 2007 to 2015. Read More

Ann Biomed Eng 2018 Dec 7. Epub 2018 Dec 7.

Department of Mechanical Engineering, The University of Akron, Akron, OH, 44325-3903, USA.

This study was focused on a semi-automated morphometric analysis of the cerebellum in the mid-sagittal plane as an alternative to tonsillar descent alone in the evaluation of Chiari malformation type 1 (CMI) patients. Morphometric analyses of posterior fossa structures were performed on mid-sagittal MRI images of 375 individuals (females, > 18 years, 235 CMI and 140 healthy controls). Twenty-six parameters including linear, angular and area measurements together with non-dimensional ratios were calculated. Read More

Arch Orthop Trauma Surg 2018 Dec 8. Epub 2018 Dec 8.

Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, University of Munich (LMU), Munich, Germany.

Purpose: Pelvic ring fractures are challenging injuries and require effective treatment due to the frequently compromised patient condition. The aim of this study was to evaluate the outcome of unstable pelvic ring injuries treated with a minimally invasive pedicle screw-rod system.

Methods: Retrospective analysis was performed for patients with an unstable pelvic ring injury that were treated with a minimally invasive anterior internal pelvic fixator (INFIX) with or without a posterior pedicle screw-rod fixator (6/2012-4/2015). Read More

Arch Orthop Trauma Surg 2018 Dec 8. Epub 2018 Dec 8.

Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cuiyingmen, Chengguan District, Lanzhou, 730030, Gansu, People's Republic of China.

Introduction: Excessive angle of the tibial tunnel may cause breakage of the posterior cortex in transtibial anatomic posterior cruciate ligament (PCL) reconstruction. However, a few studies have determined the permissible maximum angle of the tibial tunnel. The purpose of this study was to determine the permissible maximum angle of the tibial tunnel relative to the tibial plateau in transtibial anatomic PCL reconstruction and characterize the anatomic parameters of the tibial PCL attachment position. Read More

Knee Surg Sports Traumatol Arthrosc 2018 Dec 10. Epub 2018 Dec 10.

Department of Orthopaedic Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.

Purpose: Flexion-type Salter-Harris (SH) II fractures of the proximal tibia, also described as Watson-Jones (WJ) IV fractures, are rare injuries reported among adolescent athletes who are close to skeletal maturity and remain elusive. Due to this classification disagreement, the various treatments range from nonoperative to operative types, and no previous studies have explained the mechanisms of injury or the source of the fracture forces. This retrospective matched case-control study aimed to identify radiological factors that are associated with the fracture forces and to elucidate the mechanisms of these injuries. Read More

Invest Ophthalmol Vis Sci 2018 Dec;59(15):5824-5835

Department of Biology, University of Victoria, Victoria, British Columbia, Canada.

Purpose: Despite numerous studies associating Visual System Homeobox 1 (VSX1), with posterior polymorphous corneal dystrophy and keratoconus, its role in these diseases is unclear. Here we examine the pathogenicity of VSX1 missense mutations in vitro and in a mouse genetic model.

Methods: Vsx1 transcriptional repressor activity, protein stability, and subcellular localization activity, was examined using luciferase reporter-based assays, western blotting and immunolabeling, respectively, in transfected human embryonic kidney 293T cells. Read More

Genome Biol Evol 2018 Dec 11. Epub 2018 Dec 11.

Department of Life Sciences, The Natural History Museum of London, Cromwell Road, London, United Kingdom.

Stolonization in syllid annelids is a unique mode of reproduction among animals. During the breeding season, a structure resembling the adult but containing only gametes, called stolon, is formed generally at the posterior end of the animal. When stolons mature, they detach from the adult and gametes are released into the water column. Read More

JAMA 2018 Dec;320(22):2344-2353

Department of Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands.

Importance: In rare diseases it is difficult to achieve high-quality evidence of treatment efficacy because of small cohorts and clinical heterogeneity. With emerging treatments for rare diseases, innovative trial designs are needed.

Objective: To investigate the effectiveness of mexiletine in nondystrophic myotonia using an aggregated N-of-1 trials design and compare results between this innovative design and a previously conducted RCT. Read More

Oper Neurosurg (Hagerstown) 2018 Dec 10. Epub 2018 Dec 10.

Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Background And Importance: Nerve root compression by an ectatic vertebral artery is a known but easily overlooked cause of cervical radiculopathy. Management options include nonoperative conservative therapies or surgical approaches designed to relieve the compression via anterior or posterior cervical approaches.

Clinical Presentation: A 72-yr-old female presented with a 6-mo history of sharp, shooting pain in her right arm and shoulder and deltoid weakness. Read More

Poult Sci 2018 Dec 7. Epub 2018 Dec 7.

Department of Animal Science, Faculty of Agronomy Eliseu Maciel, Federal University of Pelotas, PO Box 354, 96010-900 Pelotas, RS, Brazil.

This study aimed to compare different nonlinear functions to describe the growth curve of European quails and to estimate growth curve parameters, (co)variance components, and genetic and systematic effects that affected the curve using a hierarchical Bayesian model that allows joint estimation. Three different models were fitted in the first stage (Gompertz, Logístic, and von Bertalanffy). The analyzed data set had 45,965 records of 6,838 meat quails selected for higher body weight at 42 d of age for 15 successive generations, weighed at birth, 7, 14, 21, 28, 35, and 42 d of age. Read More

Rom J Morphol Embryol 2018 ;59(3):803-809

Department of Orthodontics, Faculty of Dental Medicine, "Victor Babeş" University of Medicine and Pharmacy, Timişoara, Romania;

Maxillary expansion is one of the earliest methods of obtaining space used in the field of orthodontics. Maturing craniofacial sutures along with the increase in bone density and rigidity are main causes of high resistance of the maxilla to transversal expansion forces applied to the midpalatal suture through orthodontic appliances. Fifty-three patients, with a mean age of 16. Read More

Med Ultrason 2018 Dec;20(4):446-452

Istanbul University, Cerrahpasa Faculty of Medicine, Department of Radiology, KMPasa, Istanbul, Turkey..

Aim: To evaluate endothelial dysfunction and subclinical atherosclerosis in Behcet's disease (BD) by measuring the common carotid artery (CCA) wall stiffness and carotid intima-media thickness (CIMT).

Materials And Methods: We prospectively evaluated CIMT and the CCA wall stiffness of 34 BD patients and 28 age/sex-matched controls. CIMT measurements were performed from the posterior wall of the carotid artery approximately 10 mm proximal to the initiation of the carotid bulb using B-mode ultrasound. Read More

Biomed Res Int 2018 11;2018:8157061. Epub 2018 Nov 11.

Department of Orthopaedic Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.

Intervertebral foramen is the doorway of nerve root and it plays an important role of radiculopathy and surgical treatment of intervertebral foramen diseases. The purpose of the study is to obtain three-dimensional (3D) morphological characteristics of lumbar intervertebral foramen and their relationship with age. Pedicle-superior articular process (P-SAP), disc height between adjacent vertebra (DH), pedicle-inferior vertebrae (P-IV), inferior posterior vertebrae-superior articular process (IPV-SAP), and bony boundary area (BBA) were measured in entrance, middle slice, and exit of lumbar intervertebral foramen for 25 males of different age groups. Read More

Biomed Res Int 2018 11;2018:4149107. Epub 2018 Nov 11.

Department of Dentistry, IRCCS San Raffaele Hospital and Dental School, Vita Salute University, Via Olgettina N. 48, Zip Code 20123 Milan, Italy.

Objectives: The aim of the study was to evaluate and compare digital and traditional prosthetic workflow for posterior maxillary restorations supported by an upright and a distally tilted implant at 3-year follow-up.

Materials And Methods: Twenty-four patients were treated in the posterior maxilla with 24 immediately loaded axial and 24 distally tilted implants supporting 3-unit or 4-unit screw-retained prostheses. Three months after initial loading patients were randomly stratified into two groups: definitive traditional impressions were carried out in the control group, while digital impressions were performed in the test group. Read More

Biomed Res Int 2018 11;2018:2930783. Epub 2018 Nov 11.

Department of Paediatric Surgery, Skåne University Hospital, Department of Clinical Sciences, Paediatrics, Lund University, Lund, Sweden.

Aim Of The Study: To assess the frequency of and identify contributing factors to wound dehiscence after posterior sagittal anorectoplasty (PSARP) in children born with anorectal malformations (ARM).

Methods: Ethical approval was obtained (DNR 2017/191). Charts of all children with anorectal malformations (ARM) reconstructed with PSARP, limited PSARP, or PSARVUP at a tertiary centre of paediatric surgery between 2001 and 2016 were reviewed. Read More

Plast Reconstr Surg Glob Open 2018 Oct 1;6(10):e1963. Epub 2018 Oct 1.

Section of Plastic and Reconstructive Surgery, Yale School of Medicine, New Haven, Conn.

Background: In Crouzon's syndrome, cranial base deformities begin sequentially in the anterior cranial fossa initially, and later to the posterior cranial base. Facial characteristics are likely related to cranial base development. The temporal correlation between cranial base development and facial features is in need of clarification in Crouzon's patients, to clarify initial sites of deformity, which may impact surgical decision making. Read More

Int J Sports Phys Ther 2018 Dec;13(6):1024-1031

School of Kinesiology and Recreation, Illinois State University, Normal, IL, USA.

Background: Posterior shoulder tightness (PST), defined as limited glenohumeral (GH) horizontal adduction and internal rotation motion, is a common occurrence in overhead athletes, particularly baseball and softball players, as a result of the extreme forces on the GH joint and the high number of throwing repetitions. Despite clinical evidence suggesting the use of joint mobilizations and muscle energy techniques (MET) for treating PST, there currently are no data examining the overall effectiveness of joint mobilizations and MET to determine optimal treatment for posterior shoulder tightness.

Purpose: To compare the acute effectiveness of MET and joint mobilizations for reducing posterior shoulder tightness, as measured by passive GH horizontal adduction and internal rotation ROM, among high school baseball and softball players. Read More

Case Rep Orthop 2018 11;2018:6207024. Epub 2018 Nov 11.

Klinik für Unfall und Wiederherstellungschirurgie, Universitätsklinikum Carl Gustav Carus, Dresden, Germany.

Avulsion fractures of the calcaneal tuberosity represent a rare injury pattern that is caused by a powerful tension force from the Achilles tendon and is usually seen following minor trauma, especially in elderly patients. The objective of this study is to describe a surgical technique using cerclage wiring through cannulated screws in the treatment of extra- and intra-articular avulsion fractures of the calcaneal tuberosity and to present our results in a small patient's cohort. Through a 5. Read More

Neural Plast 2018 11;2018:6109723. Epub 2018 Nov 11.

Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing 100083, China.

Mechanisms underlying remifentanil- (RF-) induced hyperalgesia, a phenomenon that is generally named as opioid-induced hyperalgesia (OIH), still remain elusive. The ventral posterior lateral nucleus (VPL) of the thalamus, a key relay station for the transmission of nociceptive information to the cerebral cortex, is activated by RF infusion. Electroacupuncture (EA) is an effective method for the treatment of pain. Read More

Front Neurol 2018 26;9:1008. Epub 2018 Nov 26.

Department of Neurodegenerative Disorders Research, Graduate School of Medical Sciences, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan.

Writer's cramp (focal hand dystonia) is a sporadic focal dystonia that affects a specific part of the upper limb causing excessive co-contraction of antagonistic muscles. It usually presents as a task-specific dystonia, including, among others, writing of a character or playing a musical instrument. Although treatments for writer's cramp exist, medical therapy often results in unsatisfactory outcomes in patients with this type of dystonia. Read More

Front Psychiatry 2018 26;9:631. Epub 2018 Nov 26.

Research Division of Mind and Brain, Department of Psychiatry and Psychotherapy CCM, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

Adaptive recovery from a stressor fosters resilience. So far, however, few studies have examined brain functional connectivity in the aftermath of stress, with inconsistent results reported. Focusing on the immediate recovery from psychosocial stress, the current study compared amygdala resting-state functional connectivity (RSFC) before and immediately after psychosocial stress between cortisol responders and non-responders. Read More

Biomed Res Int 2018 6;2018:4535031. Epub 2018 Nov 6.

Department of Anatomy, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.

The aim of this study was to accurately identify the distribution of sensory nerve branches running to bursa with mesoscopic dissection and boundaries following the injection of gelatin into the bursa. Eighteen shoulders of 11 Korean soft cadavers (average age, 65 years; age range, 43 - 88 years) were dissected. The most prominent point of greater tubercle of the humerus (GT) was used as a reference point. Read More

Biomed Res Int 2018 8;2018:1258706. Epub 2018 Nov 8.

Department of Orthopaedic Surgery, Nihon University School of Medicine, 30-1 Oyaguchi Kami-cho, Itabashi-ku, Tokyo 173-8610, Japan.

Purpose: Minimally invasive spine stabilization (MISt) using percutaneous pedicle screws plays a significant role in palliative surgery for metastatic spinal tumors. However, few studies have investigated surgical outcomes based on the epidural spinal cord compression scale (ESCCS). The purpose of this study was to examine outcomes of metastatic spinal tumors as evaluated by ESCCS in patients treated by MISt. Read More

Arthrosc Tech 2018 Nov 29;7(11):e1231-e1234. Epub 2018 Oct 29.

Department of Orthopedics, University of Zurich, Balgrist University Hospital, Zurich, Switzerland.

Finding the way back into the glenohumeral space after a time-consuming rotator cuff reconstruction is not always easy because of swelling of the surrounding soft tissues. We present a safe and quick technical tip on how to reintroduce the arthroscope by means of a transarticular suture. After primary work in the glenohumeral space is performed and before the arthroscope is withdrawn from the joint, a monofilament suture is channeled from the anterior working portal through the glenohumeral joint to exit from the posterior portal. Read More

Arthrosc Tech 2018 Nov 15;7(11):e1135-e1139. Epub 2018 Oct 15.

Orthopedic and Trauma Department, Veteran's Memorial Teaching Hospital in Lodz, Medical University of Lodz, Lodz, Poland.

Knee flexion contracture is a clinically important complication that can be observed after trauma, after knee surgery, or as a result of osteoarthritis. When it is left untreated, knee shearing forces increase not only in the affected joint but also in the contralateral knee, leading to mechanical overload in both limbs. Conservative management is a first-line treatment option for extension deficits, but when it fails, surgical treatment is necessary. Read More

Arthrosc Tech 2018 Nov 8;7(11):e1109-e1114. Epub 2018 Oct 8.

Division of Sports Medicine, Michigan State University, East Lansing, Michigan, U.S.A.

Popliteal cysts, often referred to as Baker's cysts, are a common occurrence in the adult knee. Although controversy exists as to the exact indications for treatment, these structures can cause extreme discomfort and morbidity, including pain from rupture and symptoms from neurovascular compromise. Prior to the development of the arthroscope, open treatment of popliteal cysts was not uncommon. Read More

Arthrosc Tech 2018 Nov 1;7(11):e1079-e1087. Epub 2018 Oct 1.

Department of Orthopaedic and Trauma Surgery, Martin Luther Hospital, Berlin, Germany.

Increased tibial slope can be a cause of recurrent instability after anterior cruciate ligament reconstruction. This article presents a technique for an anterior closing-wedge osteotomy for slope correction. The indications for this procedure are patients with recurrent instability after anterior cruciate ligament reconstruction with a neutral leg axis or slightly varus deformity and a posterior slope of more than 12°. Read More

Cureus 2018 Oct 2;10(10):e3404. Epub 2018 Oct 2.

Orthopaedics, Washington Spine and Scoliosis Institute, Bethesda, USA.

Symptomatic far-lateral lumbar disc herniation is a less common causes of lumbar radiculopathy than paracentral or central disc herniation. Treatment of far-lateral disc herniation with a retroperitoneal, transpsoas approach and disc fragment excision has been described. However, treatment of far-lateral disc herniation using lateral lumbar interbody fusion (LLIF) without neural manipulation has not been described. Read More

Surg Neurol Int 2018 5;9:228. Epub 2018 Nov 5.

Department of Neurosurgery, Iran University of Medical Sciences, Tehran, Iran.

Background: Schwannoma is the most common migrating tumor in the intradural space.

Case Description: We present a patient with migrating schwannoma of the cauda which admitted with buttock and thigh pain since 2 years ago. On two preoperative lumbosacral magnetic resonance imaging (MRI), he had a L2/3 disc herniation concomitant with the intradural extra-axial mass at level of the L1/2 disc on the first MRI and then on the second one, his mass was just posterior to the L3 vertebral body, 22 months later. Read More

Surg Neurol Int 2018 2;9:225. Epub 2018 Nov 2.

Grant Medical Center, Department of Neurosurgery, Ohio Health, Columbus, Ohio, USA.

Background: Ankylosing spondylitis (AS) is a seronegative spondyloarthropathy within the spectrum of rheumatologic diseases. The systemic inflammation that characterizes AS leads to bone resorption and reformation. Pathologic remodeling may include kyphosis, osteoporosis, and multi-segment auto-fusion. Read More

Surg Neurol Int 2018 1;9:223. Epub 2018 Nov 1.

Spanish Hospital, Mendoza, Argentina.

Background: The Gorham-Stout syndrome (GSS), also known as phantom bone disease, is a rare bone condition of unknown etiology. Involvement of the spine is described in <50 cases in the literature. Here, we report a case of thoracic spine fracture dislocation in a young female who was known to have GSS. Read More

Case Rep Neurol Med 2018 8;2018:1236502. Epub 2018 Nov 8.

Department of Anesthesiology/Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

Blood culture-negative endocarditis is often severe and difficult to diagnose. It is necessary to emphasize the importance for the early diagnosis and accurate treatment of blood culture-negative endocarditis. Here, we described the relevant clinical information of a blood culture-negative but clinically diagnosed infective endocarditis complicated by intracranial mycotic aneurysm, brain abscess, and posterior tibial artery pseudoaneurysm. Read More

PLoS One 2018 11;13(12):e0208254. Epub 2018 Dec 11.

Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background: This study investigated the association of central macular thickness (CMT) and macular volume (MV) with severity of Behçet uveitis in the absence of macular edema (ME).

Methods: This retrospective, interventional study included a total 131 treatment-naïve Behçet patients with varying degree of uveitis in the absence of ME. The mean CMT and MV were obtained by spectral domain optical coherence tomography (SD ODT). Read More

Front Neurol 2018 23;9:1011. Epub 2018 Nov 23.

Hospital Clínico, Universidad de Chile, Santiago, Chile.

We report a successful bilateral globus pallidus internus-deep brain stimulation (GPi-DBS) for a Parkinson disease (PD) patient with idiopathic normal pressure hydrocephalus (INPH) and an unusually long anterior commissure-posterior commissure (AC-PC) line. A 54-year-old man presented with a history of 3 months of severe shuffling gait, rigidity, slow movements of the left side limbs, and difficulty managing finances. A brain MRI revealed marked ventriculomegaly (Evans index = 0. Read More

Front Neural Circuits 2018 23;12:105. Epub 2018 Nov 23.

Key Laboratory of Brain Functional Genomics (Ministry of Education), East China Normal University, Shanghai, China.

To perceive self-motion perception, the brain needs to integrate multi-modal sensory signals such as visual, vestibular and proprioceptive cues. Self-motion perception is very complex and involves multi candidate areas. Previous studies related to self-motion perception during passive motion have revealed that some of the areas show selective response to different directions for both visual (optic flow) and vestibular stimuli, such as the dorsal subdivision of the medial superior temporal area (MSTd) and the visual posterior sylvian fissure (VPS), although MSTd is dominated by visual signals and VPS is dominated by vestibular signals. Read More

Neuropsychiatr Dis Treat 2018 16;14:3143-3150. Epub 2018 Nov 16.

Department of Radiology, The Affiliated Xi'an Central Hospital of Xi'an Jiaotong University, Xi'an, 710004 Shaanxi, People's Republic of China,

Objective: To identify whether the amplitude of low-frequency fluctuations (ALFF) analysis has the potential to serve as a biological marker to detect alcohol-induced spontaneous brain activities and distinguish the patients with alcohol dependence from the healthy subjects.

Methods: We utilized the ALFF analysis to report on the alcohol-induced spontaneous brain activities in 29 patients with alcohol dependence (9 female, 20 male) relative to 29 status-matched healthy subjects (11 female, 18 male). Receiver operating characteristic curve was used to test the ability of the ALFF analysis in discriminating the patients with alcohol dependence from the healthy subjects. Read More