3,657 results match your criteria Posterior Cerebral Artery Stroke


Activation of the NLRP3/IL-1β/MMP-9 pathway and intracranial aneurysm rupture associated with the depletion of ERα and Sirt1 in oophorectomized rats.

J Neurosurg 2022 May 20:1-8. Epub 2022 May 20.

Objective: Subarachnoid hemorrhage (SAH) due to intracranial aneurysm (IA) rupture is often a devastating event. Since the incidence of SAH increases especially in menopause, it is crucial to clarify the detailed pathogenesis of these events. The activation of vascular nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasomes has been studied in ischemic stroke and cardiovascular disease. Read More

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Cerebral vasoreactivity in a Fabry's Disease patient.

Curr Med Imaging 2022 May 18. Epub 2022 May 18.

Pediatric Unit, Annunziata Hospital of Cosenza, Cosenza, Italy.

Background: Fabry disease (FD) is a rare X-linked multisystem lysosomal storage disease caused by partial or total deficiency of a-galactosidase A (GLA). A progressive involvement of the kidneys, heart, and brain arteries was reported. Using the transcranial color-coded duplex Doppler (TCCD), we report the case of Fabry's disease (FD) patients with a reduction in the cerebrovascular reactivity of the basilar artery (BA). Read More

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SMART syndrome: a case report.

Acta Neurol Belg 2022 May 19. Epub 2022 May 19.

Department of Medical Oncology, Hacettepe University Cancer Institute, Ankara, Turkey.

Introduction: Stroke-like migraine attacks after radiation therapy (SMART) syndrome, is a late complication of brain radiotherapy (1). Symptoms are commonly subacute in onset and involve migraine type of headache, seizures, focal neurologic deficits (2). Magnetic resonance imaging (MRI) findings are usually unilateral and posterior predominant cortical-subcortical hyperintensity, swelling and prominent gyriform (cortical and leptomeningeal) gadolinium enhancement in the areas of the brain that underwent irradiation with or without diffusion restriction (1). Read More

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Endovascular Therapy versus No Endovascular Therapy in Patients receiving Best Medical Management for Acute Isolated Occlusion of the Posterior Cerebral Artery: Systematic Review and Meta-Analysis.

Eur J Neurol 2022 May 19. Epub 2022 May 19.

Department of Neurology Heidelberg University Hospital, Heidelberg, Germany.

Background And Purpose: Endovascular therapy (EVT) is increasingly reported for treatment of isolated posterior cerebral artery (PCA) occlusions although its clinical benefit remains uncertain. This study-level meta-analysis investigated functional outcome and safety of EVT and best medical management (BMM) compared to BMM for treatment of PCA occlusion stroke.

Methods: We conducted a literature search in PubMed, Web of Science and Embase for articles reporting patients with isolated PCA occlusion stroke treated with EVT+BMM or BMM including intravenous thrombolysis. Read More

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Hypereosinophilic syndrome presenting as acute ischemic stroke, myocardial infarction, and arterial involvement: A case report.

World J Clin Cases 2022 Apr;10(11):3547-3552

Department of Central Laboratory, Liaocheng People's Hospital, Liaocheng 252000, Shandong Province, China.

Background: Simultaneous cerebral and myocardial infarction with arterial involvement has not been reported in hypereosinophilic syndrome (HES). Here, we report a patient with HES that was also associated with acute ischemic stroke, myocardial infarction, and arterial involvement of the left common carotid artery, vertebral arteries, posterior cerebral artery, and coronary artery.

Case Summary: A 64-year-old male patient was admitted with headache and right lower extremity weakness. Read More

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Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis.

Cochrane Database Syst Rev 2022 05 17;5:CD013692. Epub 2022 May 17.

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

Background: Vertebral artery stenosis (narrowing of the vertebral artery) is an important cause of posterior circulation ischaemic stroke. Medical treatment (MT) e.g. Read More

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Internal carotid artery constriction with or without superficial temporal artery-middle cerebral artery bypass for patients with giant internal carotid aneurysms.

World Neurosurg 2022 May 13. Epub 2022 May 13.

Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University; Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, China; Department of Neurosurgery, Tianjin Central Hospital for Neurosurgery and Neurology, Tianjin, China; Laboratory of Microneurosurgery, Tianjin Neurosurgical Institute, Tianjin, China; Tianjin Key Laboratory of Cerebral Vascular and Neural Degenerative Diseases, Tianjin, China. Electronic address:

Objective: The optimal management of giant internal carotid aneurysms (GICAs) is disputed due to their low incidence. This study presents the experience of the internal carotid artery (ICA) constriction therapeutic management of GICAs.

Methods: This is a retrospective cohort study involving analysis of data from medical histories and follow-up of 14 GICAs patients. Read More

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Migraine-associated common genetic variants confer greater risk of posterior vs. anterior circulation ischemic stroke☆.

J Stroke Cerebrovasc Dis 2022 May 13;31(8):106546. Epub 2022 May 13.

Department of Neurology, Miller School of Medicine, University of Miami, The Evelyn F. McKnight Brain Institute, FL, USA.

Objective: To examine potential genetic relationships between migraine and the two distinct phenotypes posterior circulation ischemic stroke (PCiS) and anterior circulation ischemic stroke (ACiS), we generated migraine polygenic risk scores (PRSs) and compared these between PCiS and ACiS, and separately vs. non-stroke control subjects.

Methods: Acute ischemic stroke cases were classified as PCiS or ACiS based on lesion location on diffusion-weighted MRI. Read More

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Transient Ischemic Attack Due to Unruptured Basilar Artery Aneurysm.

Cureus 2022 Apr 13;14(4):e24102. Epub 2022 Apr 13.

Neurology, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, IND.

Intracranial aneurysms are typically asymptomatic. They are usually incidentally detected or detected only after rupture. Ischemic stroke or transient ischemic attack (TIA) due to unruptured intracranial aneurysms (UIAs) is rare. Read More

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The Association between Migraine and Fetal-Type Posterior Cerebral Artery in Patients with Ischemic Stroke.

Cerebrovasc Dis 2022 May 13:1-7. Epub 2022 May 13.

Department of Neurology, Jinling Hospital, The First School of Clinical Medicine, Southern Medical University, Nanjing, China.

Objective: The aim of the study was to determine if migraine is associated with fetal-type posterior cerebral artery (PCA) in patients with ischemic stroke.

Method: In this cross-sectional study, patients with acute ischemic stroke were enrolled from two hospitals. The history of migraine headache was evaluated during a face-to-face interview. Read More

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A case of atlantoaxial dislocation associated with ipsilateral vertebral and carotid artery dissections: highlighting the injury biomechanics and management strategy.

Childs Nerv Syst 2022 May 14. Epub 2022 May 14.

Department of Neurosurgery, Ankara City Hospital, Ankara, Turkey.

Introduction: Traumatic cervical artery dissections carry significant morbidity and mortality among blunt trauma victims. The current paper illustrates a case with a young male who presented with atlantoaxial dislocation associated with ipsilateral carotid and vertebral artery dissections complicated by middle cerebral artery (MCA) infarction.

Case Report: We report a young male who presented to the emergency department with ipsilateral carotid and vertebral artery dissections complicated by middle cerebral artery (MCA) stroke associated with atlantoaxial dislocation after jumping into the water from a height. Read More

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The Potential Mechanism Behind Native and Therapeutic Collaterals in Moyamoya.

Front Neurol 2022 26;13:861184. Epub 2022 Apr 26.

Department of Neurosurgery, Chinese People's Liberation Army of China (PLA) General Hospital, Beijing, China.

Background And Purpose: To explore the genetic basis and molecular mechanism of native arteriogenesis and therapeutic synangiosis in moyamoya disease (MMD).

Methods: An angiography-based study using patients from a prospective trial of encephaloduroarteriosynangiosis (EDAS) surgery was performed. The spontaneous collaterals grades were evaluated according to the system described by a new grading system. Read More

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Association of Variants With Periventricular Anastomosis in Moyamoya Disease.

Stroke 2022 May 11:101161STROKEAHA121038066. Epub 2022 May 11.

Savaid Medical School, University of Chinese Academy of Sciences, Beijing (Y.X., J.Z.).

Background: The pathogenic mechanisms of periventricular anastomosis (PA) in moyamoya disease remain unknown. Here, we aimed to describe the angiographic profiles of PA and their relationships with really interesting new gene (RING) finger protein 213 (RNF213) genotypes.

Methods: We conducted a retrospective cohort study of moyamoya disease patients consecutively recruited between June 2019 and January 2021 in Beijing Tiantan Hospital, Capital Medical University, China. Read More

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Intracranial aneurysm rupture within three days after receiving mRNA anti-COVID-19 vaccination: Three case reports.

Surg Neurol Int 2022 31;13:117. Epub 2022 Mar 31.

Department of Neurosurgery, Iwate Medical University, Yahaba, Iwate, Japan.

Background: Although neurological adverse events have been reported after receiving coronavirus disease 2019 (COVID-19) vaccines, associations between COVID-19 vaccination and aneurysmal subarachnoid hemorrhage (SAH) have rarely been discussed. We report here the incidence and details of three patients who presented with intracranial aneurysm rupture shortly after receiving messenger ribonucleic acid (mRNA) COVID-19 vaccines.

Case Description: We retrospectively reviewed the medical records of individuals who received a first and/ or second dose of mRNA COVID-19 vaccine between March 6, 2021, and June 14, 2021, in a rural district in Japan, and identified the occurrences of aneurysmal SAH within 3 days after mRNA vaccination. Read More

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Endoscopic third ventriculostomy for noncommunicating hydrocephalus by vertebrobasilar dolichoectasia: A case report.

Surg Neurol Int 2022 22;13:166. Epub 2022 Apr 22.

Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

Background: Vertebrobasilar dolichoectasia (VBD) is a vasculopathy characterized by the elongation, widening, and tortuosity of a cerebral artery. Rarely, hydrocephalus results when the extended basilar artery impairs communication of the cerebral ventricle and cerebrospinal fluid dynamics. We experienced such a case when a patient underwent endoscopic third ventriculostomy (ETV) for noncommunicating hydrocephalus with VBD. Read More

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Simplified classification of cavernous internal carotid artery tortuosity: a predictor of procedural complexity and clinical outcomes in mechanical thrombectomy.

Neurol Res 2022 Apr 27:1-9. Epub 2022 Apr 27.

Department of Neurological Intervention, Dalian Municipal Central Hospital, Dalian, Liaoning, China.

Objectives: Thromboaspiration catheters are increasingly used for the endovascular treatment of large vessel stroke (LVS), while tortuous vascular anatomy still remains one major challenge in mechanical thrombectomy. Prompt assessing and understanding cavernous internal carotid artery (cICA) tortuosity may help to predict procedural complexities of mechanical thrombectomy and thus improve the clinical outcomes.

Methods: A retrospective review was performed on a cohort of LVS patients with thromboaspiration catheter. Read More

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An Unusual Presentation of a Posterior Cerebral Artery (PCA) Stroke: A Clinical Vignette.

Am J Phys Med Rehabil 2022 May 12. Epub 2022 May 12.

Department of Physical Medicine and Rehabilitation, Carolinas Medical Center, Charlotte, North Carolina.

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Intracranial atherosclerosis in pseudoxanthoma elasticum: A case-control study.

Atherosclerosis 2022 Apr 15;350:19-24. Epub 2022 Apr 15.

Department of Radiology, University Medical Center Utrecht and Utrecht University, Utrecht, the Netherlands. Electronic address:

Background And Aims: Pseudoxanthoma elasticum (PXE) is a genetic disorder characterized by systemic calcification of elastin fibers. Additionally, PXE is associated with an increased risk of stroke. It has been hypothesized that this may be caused by accelerated (intracranial) atherogenesis, as a consequence of specific genetic mutations underlying PXE. Read More

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Posterior cerebral artery dissection after excessive caffeine consumption in a teenager.

Radiol Case Rep 2022 Jun 12;17(6):2081-2084. Epub 2022 Apr 12.

Radiology Department, University General Hospital of Thessaloniki AHEPA, Thessaloniki, Kentriki Makedonia 546 21, Greece.

Arterial ischemic stroke is a rare but significant cause of neurological deficits in childhood. Even though there is a variety of risk factors, identifying the etiology can sometimes be a hard diagnostic challenge. Arteriopathies in general, and more specifically, arterial dissection is one of the uncommon pathologies that can cause incidents of pediatric stroke. Read More

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Early recurrence of ischaemic stroke of cardioembolic cause and delayed anticoagulation: a case report.

Drugs Context 2022 7;11. Epub 2022 Apr 7.

Department of Neurology, FHU NeuroVasc, Lariboisière Hospital, AP-HP, Paris, France.

Introduction: Anticoagulation therapy is used for the management of atrial fibrillation to prevent new clots from developing. However, neurologists face the challenge of when to initiate/reintroduce treatment after a recent episode of stroke without increasing haemorrhagic risk, especially if the stroke is large and/or complicated with haemorrhagic transformation.

Case Presentation: This report describes the case of a 72-year-old man who had an ischaemic stroke of the right posterior cerebral artery. Read More

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The cerebral artery in cynomolgus monkeys (Macaca fascicularis).

Exp Anim 2022 Apr 20. Epub 2022 Apr 20.

Department of Neurosurgery, Shiga University of Medical Science.

Cerebral artery structure has not been extensively studied in primates. The aim of this study was to examine the cerebrovascular anatomy of cynomolgus monkeys (Macaca fascicularis), which are one of the most commonly used primates in medical research on human diseases, such as cerebral infarction and subarachnoid hemorrhage. In this study, we investigated the anatomy and diameter of cerebral arteries from 48 cynomolgus monkey brain specimens. Read More

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Aspiration Versus Stent Retriever Thrombectomy for Distal, Medium Vessel Occlusion Stroke in the Posterior Circulation: A Subanalysis of the TOPMOST Study.

Stroke 2022 Apr 21:101161STROKEAHA121037792. Epub 2022 Apr 21.

Yong Loo Lin School of Medicine, National University of Singapore (L.Y., B.T., A.G.).

Background: The optimal endovascular strategy for reperfusing distal medium-vessel occlusions (DMVO) remains unknown. This study evaluates angiographic and clinical outcomes of thrombectomy strategies in DMVO stroke of the posterior circulation.

Methods: TOPMOST (Treatment for Primary Medium Vessel Occlusion Stroke) is an international, retrospective, multicenter, observational registry of patients treated for DMVO between January 2014 and June 2020. Read More

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Poor clinical outcome despite successful basilar occlusion recanalization in the early time window: incidence and predictors.

J Neurointerv Surg 2022 Apr 15. Epub 2022 Apr 15.

Neurology, University Hospitals Strasbourg, Strasbourg, Alsace, France.

Background: Endovascular treatment (EVT) for basilar artery occlusions (BAO) is associated with a higher rate of futile recanalization compared with anterior circulation procedures. We aimed to identify the incidence and predictors of poor clinical outcome despite successful reperfusion in current clinical practice.

Methods: We used data from the ETIS (Endovascular Treatment in Ischemic Stroke) registry, a prospective multicenter observational registry of stroke treated with EVT in France. Read More

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Radiological and clinical features of twig-like middle cerebral artery in comparison with moyamoya angiopathy: a multicenter retrospective study.

J Neurosurg 2022 Apr 15:1-9. Epub 2022 Apr 15.

1Department of Neurosurgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto.

Objective: Twig-like middle cerebral artery (T-MCA) is a rare congenital anomaly that is difficult to distinguish from moyamoya angiopathy (MMA), given the similarity of the angioarchitectures. The aim of this study was to gain insights into the radiological and clinical features of T-MCA and to distinguish this condition from MMA.

Methods: A multicenter retrospective study was conducted in 29 patients with T-MCA and 57 patients with MMA. Read More

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Palinopsia with LPDs-plus heralding a posterior-cerebral-artery ischemic stroke: the hidden face of occipital lobe seizures.

Acta Neurol Belg 2022 Apr 15. Epub 2022 Apr 15.

Section of Clinical Neurophysiology, Department of Neurology, La Paz University Hospital, Paseo de la Castellana, 261, 28046, Madrid, Spain.

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Alien Limb Phenomenon After Diffuse Corpus Callosum Ischemic Stroke.

Neurohospitalist 2022 Apr 21;12(2):295-300. Epub 2022 Feb 21.

Department of Neuromedicine, Bangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research & SSKM Hospital, Kolkata, West Bengal, India.

The alien limb is a phenomenon characterized by a cluster of clinical features wherein the limb behaves autonomously and as separated from a person's identity. We herein report a 36-year-old Indian female with multiple comorbidities who presented with recurrent episodes of limb-shaking transient ischemic attacks for 1 year, followed by left-sided hemiplegia. During recovering, the patient noticed a feeling that as if her left hand did not belong to herself and acted autonomously (alien limb phenomenon) along with visuospatial deficits. Read More

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A 14-year-old Girl with Right-Sided Weakness and Speech Difficulty.

Neurohospitalist 2022 Apr 16;12(2):408-412. Epub 2022 Feb 16.

Department of Pediatrics, Section of Child Neurology, University of Colorado School of Medicine, Aurora, CO, USA.

We herein report a case of Childhood Primary Central Nervous System (CNS) Angiitis. This case consisted of a 14-year-old girl who presented with right-sided weakness, aphasia, and a fever. A Magnetic Resonance Imaging of the brain showed multifocal areas of ischemia. Read More

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Machine Learning-Based Prediction of Subsequent Vascular Events After 6 Months in Chinese Patients with Minor Ischemic Stroke.

Int J Gen Med 2022 7;15:3797-3808. Epub 2022 Apr 7.

Department of Neurology, The Second People's Hospital of Kunshan, Suzhou, 215300, People's Republic of China.

Background: To develop and validate a machine learning model for predicting subsequent vascular events (SVE) 6 months after mild ischemic stroke (MIS) in Chinese patients.

Methods: A retrospective analysis was performed on 495 newly diagnosed MIS patients by collecting their basic information, past medical history, initial NIHSS score, symptoms, obstruction sites of MIS, and MRI results. According to the ratio of 7:3, the dataset was divided into a training set (n=346) and a testing set (n=149) through stratified random sampling. Read More

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Internal Carotid Artery Tortuosity: Impact on Mechanical Thrombectomy.

Stroke 2022 Apr 11:101161STROKEAHA121037904. Epub 2022 Apr 11.

Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan. (J.K., M.S., M.K., K. Toyoda).

Background: Although tortuosity of the internal carotid artery (ICA) can pose a significant challenge when performing mechanical thrombectomy, few studies have examined the impact of ICA tortuosity on mechanical thrombectomy outcomes.

Methods: In a registry-based hospital cohort, consecutive patients with anterior circulation stroke in whom mechanical thrombectomy was attempted were divided into 2 groups: those with tortuosity in the extracranial or cavernous ICA (tortuous group) and those without (nontortuous group). The extracranial ICA tortuosity was defined as the presence of coiling or kinking. Read More

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Artery of Percheron Infarction: A Case Report of Bilateral Thalamic Stroke Presenting with Acute Encephalopathy.

Case Rep Neurol Med 2022 30;2022:8385841. Epub 2022 Mar 30.

University of Missouri-Kansas City School of Medicine, 2411 Holmes St, Kansas City, MO 64108, USA.

The artery of Percheron (AOP) is a relatively rare anatomic variant in which a solitary arterial trunk branches from the proximal segment of the posterior cerebral artery and provides arterial supply to the paramedian region of the thalami bilaterally and often to the rostral part of the midbrain. Occlusion of the artery of Percheron results in bilateral paramedian thalamic infarcts with and without midbrain involvement. Recognition of this condition as an acute stroke may be challenging due to various nonlocalized clinical presentations, given the wide range of neurological functions subserved by the thalamus. Read More

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