84,208 results match your criteria Portal Vein Thrombosis


Inpatients Sign On: An Opportunity to Engage Hospitalized Patients and Caregivers Using Inpatient Portals.

Med Care 2018 Dec 4. Epub 2018 Dec 4.

Department of Pediatrics, University of Wisconsin School of Medicine and Public Health.

Background: Inpatient portals are online patient portals linked to electronic health records that provide hospitalized patients and caregivers secure access to real-time clinical information and tools to enhance their communication with providers and hospital experience.

Objective: The main objective of this commentary was to provide a perspective that inpatient portals are innovative tools poised to engage patients and caregivers during hospitalization and, thus, enhance patient-centered care.

Results: Inpatient portals are desired by patients and caregivers and may contribute to improved recognition of their inpatient care team, knowledge of their treatment plan and overall inpatient experience. Read More

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December 2018

Feasibility of closed-MLC tracking using high sensitivity and multi-layer electronic portal imagers.

Phys Med Biol 2018 Dec 6;63(23):235030. Epub 2018 Dec 6.

Department of Radiation Oncology, Division of Medical Physics and Biophysics, Brigham and Women's Hospital, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, MA 02115, United States of America. Author to whom any correspondence should be addressed.

In radiation therapy, improvements in treatment conformality are often limited by movement of target tissue. To better treat the target, tumor tracking strategies involving beam's-eye-view (BEV) have been explored. However, localization surrogates like implanted fiducial markers may sometimes leave the field-of-view (FOV), as defined by the linear accelerator (LINAC) multi-leaf collimator (MLC). Read More

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December 2018
1 Read

Incidental Hepatic Tissue Obtained via Routine Cholecystectomy.

Int J Surg Pathol 2018 Dec 6:1066896918817374. Epub 2018 Dec 6.

2 University of California, Irvine, CA, USA.

Background: The hepatic tissue that may occupy specimens from routine cholecystectomies has yet to be studied. Our objectives were to determine the prevalence of hepatic tissue obtained at routine cholecystectomy, to determine whether such hepatic tissue can histologically withstand technical artifacts commonly associated with cholecystectomy, and to determine whether examining such hepatic tissue has diagnostic utility.

Materials And Methods: We retrospectively reviewed 50 specimens from routine cholecystectomies that were performed by surgeons who lacked knowledge of our study. Read More

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December 2018
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Outcomes following neonatal portal vein thrombosis: A descriptive, single-center study and review of anticoagulant therapy.

Pediatr Blood Cancer 2018 Dec 5:e27572. Epub 2018 Dec 5.

Division of Neonatology, Department of Pediatrics, McMaster Children's Hospital, McMaster University, Hamilton, Ontario, Canada.

Background: Neonatal portal vein thrombosis (PVT) is uncommon with potentially serious complications that may manifest in infancy and childhood.

Objective: The primary aim of our study was to describe the short-term and long-term outcomes of neonatal PVT.

Methods: A retrospective chart review was conducted from 2008 to 2016 of neonates diagnosed with PVT. Read More

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December 2018

Portal Hypertension.

Can J Gastroenterol Hepatol 2018 4;2018:1289156. Epub 2018 Nov 4.

Medicina Interna 1, ARNAS-Civico, Di Cristina-Benfratelli, Palermo, Italy.

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November 2018

Sugar Metabolism Regulates Flavor Preferences and Portal Glucose Sensing.

Front Integr Neurosci 2018 21;12:57. Epub 2018 Nov 21.

The John B. Pierce Laboratory, Yale University, New Haven, CT, United States.

In most species, including humans, food preference is primarily controlled by nutrient value. In particular, glucose-containing sugars exert exquisitely strong effects on food choice via gut-generated signals. However, the identity of the visceral signals underlying glucose's rewarding effects remains uncertain. Read More

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November 2018
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Long-Term Cholic Acid Treatment in a Patient with Zellweger Spectrum Disorder.

Case Rep Gastroenterol 2018 Sep-Dec;12(3):661-670. Epub 2018 Nov 21.

Division of Pediatric Gastroenterology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

Zellweger spectrum disorders (ZSDs) are a subgroup of peroxisomal biogenesis disorders with a generalized defect in peroxisome function. Liver disease in ZSDs has been associated with the lack of peroxisomal β-oxidation of C-bile acid intermediates to form primary C-bile acids, which prevents normal physiologic feedback and leads to accumulation of hepatotoxic bile acid intermediates. Primary bile acid therapy, oral cholic acid (CA), as adjunctive treatment for ZSDs, restores physiologic feedback inhibition on bile acid synthesis and inhibits formation of hepatotoxic bile acid intermediates. Read More

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November 2018

Érysipèle.

Rev Prat 2016 Nov;67(9):991-996

Service de médecine interne et polyvalente, centre hospitalier de Polynésie française, Pirae, Polynésie française.

Erysipelas. Erysipelas is a non-necrotizing acute dermohypodermitis of streptococcal origin (group A beta-hemolytic streptococcus) that usually affects adults and tends to reoccur. Risk factors recognized by the 2000 Consensus Conference are lymphedema, the existence of a gateway and obesity. Read More

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November 2016

Application of real time contrast-enhanced ultrasound in differential diagnosis of liver malignancies.

Authors:
Hongling Li Jin Li

Can J Physiol Pharmacol 2018 Dec 3. Epub 2018 Dec 3.

Puai Hospital affiliated to Tongji Medical College of Huazhong Science and Technology University, Wuhan, China ;

Objective: To evaluate the value of real time contrast-enhanced ultrasound in differential diagnosis of malignant liver tumors.

Methods: 60 patients pathologically diagnosed with liver cancer from May 2016 to May 2017 were selected as the objects. All patients received ultrasonic diagnosis followed by the observation on dynamic contrast enhancement of the image and the analysis on perfusion characteristics and difference in contrast-enhanced ultrasound results in patients with different types of liver cancer. Read More

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December 2018

CARE Dose 4D combined with sinogram-affirmed iterative reconstruction improved the image quality and reduced the radiation dose in low dose CT of the small intestine.

J Appl Clin Med Phys 2018 Dec 3. Epub 2018 Dec 3.

Department of Radiology, The Second Affiliated Hospital of Nantong University, Jiangsu, China.

Objective: Multislice computed tomography (MSCT) has been used for diagnosis of small intestinal diseases. However, the radiation dose is a big problem. This study was to investigate whether CARE Dose 4D combined with sinogram-affirmed iterative reconstruction (SAFIRE) can provide better image quality at a lower dose for imaging small intestinal diseases compared to MSCT. Read More

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December 2018
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Water stress in Musa spp.: A systematic review.

PLoS One 2018 3;13(12):e0208052. Epub 2018 Dec 3.

Department of Biological Sciences, State University of Santa Cruz (UESC), Ilhéus, Bahia, Brazil.

Background: The cultivation of bananas and other plants is limited by environmental stresses caused by climate change. In order to recognize physiological, biochemical and molecular components indicated to confer tolerance to water stress in Musa spp. we present the first systematic review on the topic. Read More

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December 2018

Sequence variations of PKHD1 underlie congenital hepatic fibrosis in a Chinese family.

Eur J Gastroenterol Hepatol 2018 Nov 30. Epub 2018 Nov 30.

The Research Center for Medical Genomics, Key Laboratory of Cell Biology, Ministry of Public Health, Key Laboratory of Medical Cell Biology, Ministry of Education, College of Basic Medical Science, China Medical University.

Objective: Congenital hepatic fibrosis (CHF) is a developmental disorder of the portobiliary system characterized by hepatic fibrosis, portal hypertension, and renal cystic disease. The aim of our study was to identify the disease-causing gene of a Chinese family with CHF.

Patients And Methods: Whole-exome sequencing was performed in the family with CHF and variants were confirmed by Sanger sequencing. Read More

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November 2018

Phenology and Productivity in a Montane Bird Assemblage: Trends and Responses to Elevation and Climate Variation.

Glob Chang Biol 2018 Dec 1. Epub 2018 Dec 1.

The Institute for Bird Populations, Point Reyes Station, CA, P.O. Box 1346, 94956-1346.

Climate variation has been linked to historical and predicted future distributions and dynamics of wildlife populations. However, demographic mechanisms underlying these changes remain poorly understood. Here we assessed variation and trends in climate (annual snowfall and spring temperature anomalies) and avian demographic variables from mist-netting data (breeding phenology and productivity) at six sites along an elevation gradient spanning the montane zone of Yosemite National Park between 1993 and 2017. Read More

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December 2018

Tei index is associated with survival in cirrhosis patients treated with transjugular intrahepatic portosystemic shunt.

Echocardiography 2018 Dec 1. Epub 2018 Dec 1.

Department of Ultrasound, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Background: Transjugular intrahepatic portosystemic shunt (TIPS) is the method of choice for the treatment of portal hypertension. The Tei index is the most sensitive indicator of myocardial function.

Design: This study enrolled 31 patients with cirrhosis who underwent TIPS and were followed up over a median period of 34 months (range 2-60 months). Read More

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December 2018

Liver stiffness in non-cirrhotic portal hypertension - The Devil is in the diagnosis.

Hepatology 2018 Dec 1. Epub 2018 Dec 1.

Dept. of Clinical Medicine, "Sapienza" University of Rome, Rome, Italy.

We have read with great interest the article by Vuppalanchi et al. , who studied the diagnostic role of liver stiffness measurements (LSM) in patients with non-cirrhotic portal hypertension (NCPH) due to hepatic (nodular regenerative hyperplasia-NRH) or prehepatic origin (portal vein thrombosis-PVT). The role of LSM to identify a cirrhosis as the cause of the portal hypertension is well established and the evidence of PVT in any imaging technique is sufficient to attribute the cause of portal hypertension to PVT and does not require further histological or elastographical confirmation. Read More

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December 2018
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Changes in arterial oxygenation after portal decompression in Budd-Chiari syndrome patients with hepatopulmonary syndrome.

Eur Radiol 2018 Nov 30. Epub 2018 Nov 30.

Department of Interventional Therapy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 17 Panjiayuan Nanli, Chaoyang District, Beijing, 100021, China.

Objectives: To evaluate the changes in arterial oxygenation after portal decompression in Budd-Chiari syndrome (BCS) patients with hepatopulmonary syndrome (HPS).

Methods: From June 2014 to June 2015, all patients with BCS who underwent balloon angioplasty or transjugular intrahepatic portosystemic shunt (TIPS) creation at our institution were eligible for inclusion in this study. Arterial blood gas analysis was performed with the patient in an upright position and breathing room air at 2-3 days and 1 and 3 months after the procedure. Read More

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November 2018
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Identification of Key Potential Targets and Pathway for Arsenic Trioxide by Systemic Bioinformatics Analysis in Pancreatic Cancer.

Pathol Oncol Res 2018 Nov 30. Epub 2018 Nov 30.

Department of Laboratory Diagnostics, Changhai Hospital, Second Military Medical University, Shanghai, 200433, China.

Arsenic trioxide is an approved chemotheraputic agent for the treatment of acute promyelocytic leukemia (APL). Recently, numerous studies suggested that arsenic trioxide acts as anti-cancer roles in various human malignancies. However, the molecular mechanisms are not fully elucidated. Read More

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November 2018

The feasibility and efficacy of two micro-portal video-assisted thoracic surgery in pulmonary lobectomy for lung cancer.

J Thorac Dis 2018 Oct;10(10):5898-5903

Department of Thoracic Surgery, Tangdu Hospital, The Air Force Medical University, Xi'an 710038, China.

Background: Conventional three-port video-assisted thoracic surgery (VATS) is well established internationally. Meanwhile, uniportal VATS technique has been become more and more popular in the past two decades. However, both methods have their merits and drawbacks. Read More

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October 2018

Clinical and Radiological Outcomes of Foraminal Decompression Using Unilateral Biportal Endoscopic Spine Surgery for Lumbar Foraminal Stenosis.

Clin Orthop Surg 2018 Dec 21;10(4):439-447. Epub 2018 Nov 21.

Department of Orthopedic Surgery, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.

Background: Since open Wiltse approach allows limited visualization for foraminal stenosis leading to an incomplete decompression, we report the short-term clinical and radiological results of unilateral biportal endoscopic foraminal decompression using 0° or 30° endoscopy with better visualization.

Methods: We examined 31 patients that underwent surgery for neurological symptoms due to lumbar foraminal stenosis which was refractory to 6 weeks of conservative treatment. All 31 patients underwent unilateral biportal endoscopic far-lateral decompression (UBEFLD). Read More

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December 2018
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Advances in therapeutic options for portal hypertension.

Therap Adv Gastroenterol 2018 25;11:1756284818811294. Epub 2018 Nov 25.

Liver Vascular Biology Research Group, Barcelona Hepatic Hemodynamic Laboratory, IDIBAPS Biomedical Research Institute, CIBEREHD, Rosselló 149, 4th floor, 08036 Barcelona, Spain.

Portal hypertension represents one of the major clinical consequences of chronic liver disease, having a deep impact on patients' prognosis and survival. Its pathophysiology defines a pathological increase in the intrahepatic vascular resistance as the primary factor in its development, being subsequently aggravated by a paradoxical increase in portal blood inflow. Although extensive preclinical and clinical research in the field has been developed in recent decades, no effective treatment targeting its primary mechanism has been defined. Read More

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November 2018

Portal hypertension: The desperate search for the placenta.

Curr Res Transl Med 2018 Nov 29. Epub 2018 Nov 29.

Department of Surgery. School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.

We propose that the circulatory impairments produced, in both portal hypertension and liver cirrhosis, to a certain degree resemble those characterizing prenatal life in the fetus. In fact, the left-right circulatory syndrome is common in cirrhotic patients and in the fetus. Thus, in patients with portal hypertension and chronic liver failure, the re-expression of a blood circulation comparable to fetal circulation is associated with the development of similar amniotic functions, i. Read More

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November 2018

Acute restraint stress induces cholecystokinin release via enteric apelin.

Neuropeptides 2018 Nov 26. Epub 2018 Nov 26.

Department of Histology and Embryology, Akdeniz University, Faculty of Medicine, Antalya, Turkey.

Stress increases the apelin content in gut, while exogenous peripheral apelin has been shown to induce cholecystokinin (CCK) release. The present study was designed to elucidate (i) the effect of acute stress on enteric production of apelin and CCK, (ii) the role of APJ receptors in apelin-induced CCK release depending on the nutritional status. CCK levels were assayed in portal vein blood samples obtained from stressed (ARS) and non-stressed (NS) rats previously injected with APJ receptor antagonist F13A or vehicle. Read More

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November 2018

Percutaneous portal vein recanalization using self-expandable nitinol stents in patients with non-cirrhotic non-tumoral portal vein occlusion.

Diagn Interv Imaging 2018 Nov 28. Epub 2018 Nov 28.

Department of Radiodiagnostic and interventional radiology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.

Purpose: The purpose of this study was to evaluate the feasibility, safety, and efficacy of portal vein recanalization (PVR) and propose a new classification for better selecting candidates with portal vein occlusion (PVO) in whom PVR could be feasible.

Materials And Methods: The charts of 15 non-cirrhotic patients in whom stent placement using a trans-hepatic approach was attempted for the treatment of PVO with cavernous transformation were reviewed. There were 12 men and 5 women with a mean age of 47±12 years (range: 22-60 years). Read More

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November 2018

A Method for Approximating Future Entry of Generic Drugs.

Value Health 2018 Dec 11;21(12):1382-1389. Epub 2018 Jun 11.

Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Objectives: To develop and test a method for approximating generic entry of top-selling drugs.

Methods: The procedure involved 1) identifying products' key patents as those with a patent term restoration extension (whenever relevant) or otherwise as the first expiring patent listed in the US Food and Drug Administration's patent register, 2) determining whether the key patent had been extended through an associated pediatric extension, 3) identifying other regulatory exclusivities associated with the drug, and 4) categorizing key patents as active ingredient (or extended) patents versus secondary patents. The accuracy and precision of the procedure's predictions were then tested against a database containing the timing of generic entry for 170 top-selling drugs that lost market exclusivity between 2000 and 2012, on the basis of Medicaid data. Read More

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December 2018

Early screening for gestational diabetes mellitus is not associated with improved pregnancy outcomes: an observational study including 9795 women.

Diabetes Metab 2018 Nov 28. Epub 2018 Nov 28.

Paris 13 university, Sorbonne Paris Cité, AP-HP, Jean-Verdier hospital, department of obstetrics and gynecology, Bondy, France.

Aims: In addition to screening for hyperglycaemia during pregnancy after 24 weeks of gestation (WG), the current guidelines also suggest screening in early pregnancy and referring women with early gestational diabetes mellitus (eGDM) or overt diabetes (OD) for immediate care. Our aim was to evaluate this strategy.

Methods: This study evaluated, at our hospital (2012-2016), whether the incidence of a predefined composite outcome (preeclampsia, large-for-gestational-age infant, shoulder dystocia) and secondary outcomes was different when women were screened only after 22WG ('late screening only') or before 22WG and treated for eGDM or OD if present, with repeat screening after 22WG if absent ('early ± late screening'). Read More

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November 2018

Medical management of haemorrhagic hereditary telangiectasia in adult patients.

Med Clin (Barc) 2018 Nov 27. Epub 2018 Nov 27.

Unidad de Telangiectasia Hemorrágica Hereditaria, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de LLobregat, Barcelona, España; Facultad de Medicina y Ciencias de la Salud, Universitat de Barcelona, Barcelona, España; Unidad de Hepatología y Trasplante hepático, Servicio de Aparato Digestivo, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de LLobregat, Barcelona, España.

Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant inherited Rare Disease that causes a systemic anomalous vascular overgrowth. The approach and follow-up of these patients should be from multidisciplinary units. Its diagnosis is carried out according to Curaçao clinical Criteria. Read More

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November 2018

Modifications to Expose Porta Hepatis for Laparoscopic Portoenterostomy Easier in Biliary Atresia.

J Surg Res 2019 Jan 10;233:368-375. Epub 2018 Sep 10.

Department of General surgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu, China.

Background: Laparoscopic Kasai portoenterostomy (LKPE) is generally regarded to have a poorer outcome for surgical treatment of uncorrectable biliary atresia. We herein described our initial experience of some modifications to make LKPE easier in the treatment of type III biliary atresia (BA).

Methods: During the period July 2012-October 2016, a total of 25 infants with type III BA were treated with a modified LKPE technique. Read More

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January 2019
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Intestinal absorption of black chokeberry cyanidin 3-glycosides is promoted by capsaicin and capsiate in a rat ligated small intestinal loop model.

Food Chem 2019 Mar 22;277:323-326. Epub 2018 Oct 22.

Sapporo Anti-Aging Laboratory Co., Ltd., Sapporo 061-3204, Japan; Hokkaido Food and Health Research Institute, Sapporo 004-0863, Japan.

Recent studies have shown that aronia (black chokeberry) and haskap fruits (contain anthocyanins) have beneficial health effects in animals and humans. However, some reports have shown that anthocyanin is poorly absorbed in the small intestine. In this study, we compared the intestinal absorption of aronia and haskap anthocyanins by using rats with a ligated small intestinal loop and cannulated portal vein. Read More

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Biliary atresia: 20-40-year follow-up with native liver in an Italian centre.

J Pediatr Surg 2018 Nov 6. Epub 2018 Nov 6.

Department of Paediatric Surgery, "Spedali Civili" Children's Hospital, 25123, Brescia, Italy; Department of Clinical and Experimental Sciences, University of Brescia, 25123, Brescia, Italy.

Introduction: Biliary atresia (BA) represents the leading indication for liver transplantation in childhood. Only few studies reported the outcome of patients who survived more than 20 years on their native liver, and up to date there are no Italian data available. We reported our 40-year single centre experience with long-term follow-up of BA patients. Read More

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November 2018
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Can post-hoc video review of robotic pancreaticoduodenectomy predict portal/superior mesenteric vein margin status in pancreatic adenocarcinoma?

HPB (Oxford) 2018 Nov 27. Epub 2018 Nov 27.

Department of Surgery, University of Pittsburgh Medical Center, 5150 Center Ave, Pittsburgh, PA 15232, USA; Department of Surgery, West Virginia University, PO Box 9238 HSCS, Morgantown, WV 26506, USA. Electronic address:

Background: Achieving margin negative resection is a significant determinant of outcome in pancreatic adenocarcinoma (PDA). However, because of the fibrotic nature of PDA, it can be difficult to discriminate fibrosis from active disease intra-operatively. We sought to determine if post-hoc video review of robotic pancreatico-duodenectomy (RPD) could predict the portal/superior mesenteric vein (PV/SMV) margin status on final pathology. Read More

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November 2018
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Left Renal Vein Ligation for Spontaneous Splenorenal Shunts During Deceased-Donor Orthotopic Liver Transplant Is Safe and Can Mitigate Complications from Portal Steal: A Case Series.

Exp Clin Transplant 2018 Nov 28. Epub 2018 Nov 28.

From the Division of Transplantation, The Ohio State University Wexner Center, Columbus, Ohio, USA.

Objectives: Large spontaneous splenorenal shunts can result in portal vein steal syndrome and is a risk factor for portal vein thrombosis after orthotopic liver transplant. Disconnection of these shunts by left renal vein ligation has been suggested as a potential technique for improving portal venous flow and mitigating risk of portal vein thrombus, thus improving graft perfusion. We present a series of 6 patients who underwent left renal vein ligation for spontaneous splenorenal shunts and their outcomes. Read More

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November 2018

Understanding Secure Messaging in the Inpatient Environment: A New Avenue for Communication and Patient Engagement.

Appl Clin Inform 2018 Oct 5;9(4):860-868. Epub 2018 Dec 5.

Department of Family Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States.

Background:  Patient portals, and the secure messaging feature in particular, have been studied in the outpatient setting, but research in the inpatient setting is relatively less mature.

Objective:  To understand the topics discussed in secure messaging in the inpatient environment, we analyzed and categorized messages sent within an inpatient portal.

Materials And Methods:  This observational study examined the content of all secure messages sent from December 2013 to June 2017 within an inpatient portal at a large Midwestern academic medical center (AMC). Read More

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October 2018
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Alterations in the lipid profiles and circulating liver enzymes in individuals infected by Schistosoma mansoni.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):795-801

Laboratório Avançado de Saúde Pública, Instituto Gonçalo Moniz, Salvador, BA, Brasil.

Introduction: Portal hypertension and periportal fibrosis commonly occur in severe Schistosoma mansoni infection. Changes in lipid profile and elevated levels of circulating liver enzymes have also been described in infected individuals. The present study sought to assess the alterations in laboratory parameters associated with liver disorder in individuals infected by S. Read More

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Laparoscopic splenectomy: a new approach.

Clinics (Sao Paulo) 2018 Nov 29;73:e16536. Epub 2018 Nov 29.

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Objectives: To introduce a new laparoscopic splenectomy (LS) approach.

Methods: Sixteen patients underwent LS with general anaesthesia and carbon dioxide pneumoperitoneum. The details of the surgery are as follows: 1. Read More

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November 2018
3 Reads

Prospective Comparison of Bleeding Complications Between Right and Left Approaches in Percutaneous Biliary Drainage.

Surg Laparosc Endosc Percutan Tech 2018 Dec 3. Epub 2018 Dec 3.

Department of Surgery, University of Buenos Aires.

Purpose: The present study aimed to determine whether the percentage of bleeding complications differs between the right and the left approaches in percutaneous biliary drainage (PBD) in adult patients.

Materials And Methods: This was a prospective, descriptive, nonrandomized comparative and longitudinal study. We included adult patients over 18 years of age who underwent a PBD. Read More

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December 2018

Construction of immune-related risk signature for renal papillary cell carcinoma.

Cancer Med 2018 Dec 5. Epub 2018 Dec 5.

Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.

The kidney renal papillary cell carcinoma (KIRP) is a relatively rare type of kidney cancer. There has been no investigation to find a robust signature to predict the survival outcome of KIRP patients in the aspect of tumor immunology. In this study, 285 KIRP samples from The Cancer Genome Atlas (TCGA) were randomly divided into training and testing set. Read More

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December 2018
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Differentiation between inflammatory myofibroblastic tumor and cholangiocarcinoma manifesting as target appearance on gadoxetic acid-enhanced MRI.

Abdom Radiol (NY) 2018 Dec 4. Epub 2018 Dec 4.

Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, Ilwon-Dong, Kangnam-Ku, Seoul, 135-710, Republic of Korea.

Purpose: To determine the differential features of inflammatory myofibroblastic tumor (IMT) and intrahepatic cholangiocarcinoma (ICC) manifesting as target appearance on gadoxetic acid-enhanced MRI.

Methods: Twenty-seven patients with 36 IMTs (1.2-6. Read More

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December 2018
1 Read

Preoperative Thrombocytopenia May Predict Poor Surgical Outcome after Extended Hepatectomy.

Can J Gastroenterol Hepatol 2018 1;2018:1275720. Epub 2018 Nov 1.

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Background: It is a novel idea that platelet counts may be associated with postoperative outcome following liver surgery. This may help in planning an extended hepatectomy (EH), which is a surgical procedure with high morbidity and mortality.

Aim: The aim of this study was to evaluate the predictive potential of platelet counts on the outcome of EH in patients without portal hypertension, splenomegaly, or cirrhosis. Read More

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November 2018

Video Capsule Endoscopy in the Assessment of Portal Hypertensive Enteropathy.

Int J Hepatol 2018 1;2018:5109689. Epub 2018 Nov 1.

University of Massachusetts School of Medicine, USA.

Background: The features of the portal hypertension enteropathy (PHE) vary from mild mucosal changes to varices with or without bleeding. The prevalence and the development are not fully understood.

Aim: Our aim is to examine the prevalence and the different manifestations of PHE using video capsule endoscopy (VCE). Read More

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November 2018
2 Reads

The Clinical Utility of Virtual Reality in Neurorehabilitation: A Systematic Review.

J Cent Nerv Syst Dis 2018 27;10:1179573518813541. Epub 2018 Nov 27.

Graduate Program in Rehabilitation Sciences, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.

Background: Virtual reality (VR) experiences (through games and virtual environments) are increasingly being used in physical, cognitive, and psychological interventions. However, the impact of VR as an approach to rehabilitation is not fully understood, and its advantages over traditional rehabilitation techniques are yet to be established.

Method: We present a systematic review which was conducted according to (PRISMA). Read More

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November 2018
1 Read

Patients' Expectations for Longevity of Kidney Transplant.

Prog Transplant 2018 Dec 4:1526924818817045. Epub 2018 Dec 4.

5 Montefiore Einstein Center for Transplantation, Montefiore Medical Center-Albert Einstein College of Medicine, Bronx, NY, USA.

Introduction:: Prior to transplantation, the transplant team is responsible for transplant education and posttransplant expectations. The majority of outcomes research focuses on 1- and 3-year graft survival, with a lack of literature focused upon whether patients have a realistic understanding of how many years deceased donor kidneys can be expected to function after transplant.

Objective:: To determine whether potential kidney transplant patients' expectations for how long a deceased donor kidney will function after transplantation differs from transplant surgeons, using quantitative analysis. Read More

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December 2018

Dépister précocement cancer du foie et hypertension portale.

Rev Prat 2017 Sep;67(7):730-735

AP-HP, service d'hépatologie, Hôpitaux universitaires Paris-Seine- Saint-Denis, site Jean-Verdier, Bondy ; UFR SMBH, université Paris-13, Paris-Cité-Sorbonne ; Inserm UMR 1162, Paris, France.

Management and surveillance of compensated Cirrhosis. Patients with compensated cirrhosis are now identified early using non-invasive fibrosis tests. Therapeutic advances in hepatology, in particular antiviral agents, have changed their prognosis by dramatically reducing the occurrence of liver complications, whether hepatic decompensation or hepatocellular carcinoma. Read More

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September 2017

Systemic Dissemination of Injected Foreign Material.

J Forensic Sci 2018 Dec 4. Epub 2018 Dec 4.

Forensic Science SA, GPO Box 2790, Adelaide, 5001.

A 32-year-old woman collapsed following an intravenous injection of material that included crushed pharmaceutical tablets. Resuscitation was attempted but was unsuccessful. She had an extensive past medical history of complications resulting from intravenous drug use. Read More

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December 2018
3 Reads

Comparative models for human nasal infections and immunity.

Dev Comp Immunol 2018 Dec 1. Epub 2018 Dec 1.

University of New Mexico, Department of Biology, Center for Evolutionary and Theoretical Immunology (CETI), Albuquerque, New Mexico, USA.

The human olfactory system is a mucosal surface and a major portal of entry for respiratory and neurotropic pathogens into the body. Understanding how the human nasopharynx-associated lymphoid tissue (NALT) halts the progression of pathogens into the lower respiratory tract or the central nervous system is key for developing effective cures. Although traditionally mice have been used as the gold-standard model for the study of human nasal diseases, mouse models present important caveats due to major anatomical and functional differences of the human and murine olfactory system and NALT. Read More

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December 2018
2 Reads

Raltegravir-intensified initial antiretroviral therapy in advanced HIV disease in Africa: A randomised controlled trial.

PLoS Med 2018 Dec 4;15(12):e1002706. Epub 2018 Dec 4.

Medical Research Council Clinical Trials Unit at University College London, University College London, London, United Kingdom.

Background: In sub-Saharan Africa, individuals infected with HIV who are severely immunocompromised have high mortality (about 10%) shortly after starting antiretroviral therapy (ART). This group also has the greatest risk of morbidity and mortality associated with immune reconstitution inflammatory syndrome (IRIS), a paradoxical response to successful ART. Integrase inhibitors lead to significantly more rapid declines in HIV viral load (VL) than all other ART classes. Read More

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December 2018
1 Read

Benefits of Splenectomy and Curative Treatments for Patients with Hepatocellular Carcinoma and Portal Hypertension: a Retrospective Study.

J Gastrointest Surg 2018 Dec 3. Epub 2018 Dec 3.

Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Background: We aimed to explore the benefit of splenectomy combined with curative treatments (liver resection or local ablation) for patients with hepatocellular carcinoma and portal hypertension.

Methods: The records of 239 patients with hepatocellular carcinoma and portal hypertension undergoing either splenectomy combined with liver resection or local ablation were reviewed retrospectively. Perioperative complications and survival outcome were evaluated, and liver function 1 year later was reassessed according to the Child score. Read More

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December 2018

Repeated Autologous Bone Marrow Transfusion through Portal Vein for Treating Decompensated Liver Cirrhosis after Splenectomy.

Gastroenterol Res Pract 2018 29;2018:4136082. Epub 2018 Oct 29.

Department of General Surgery, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.

Objective: This study is aimed at examining the impact of repeated intraportal autologous bone marrow transfusion (ABMT) in patients with decompensated liver cirrhosis after splenectomy.

Methods: A total of 25 patients with decompensated liver cirrhosis undergoing splenectomy were divided into ABMT and control groups. The portal vein was cannulated intraoperatively using Celsite Implantofix through the right gastroomental vein. Read More

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October 2018
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Controlled attenuation parameter: A measure of hepatic steatosis in patients with cystic fibrosis.

J Cyst Fibros 2018 Nov 30. Epub 2018 Nov 30.

Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA, United States. Electronic address:

Background: Hepatic steatosis is a common manifestation of CF-related liver disease(CFLD). Controlled attenuation parameter(CAP) measurement during transient elastography(TE) semiquantifies liver steatosis. We examined the relationship between CAP and CFLD severity, clinical factors and liver stiffness measurements(LSM). Read More

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November 2018
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Gallbladder varices in a pediatric patient after roux-en-Y gastric bypass.

J Pediatr Surg 2018 Dec 25;53(12):2511-2513. Epub 2018 Aug 25.

Department of Pediatric Surgery, University of Arkansas for Medical Sciences, Little Rock, AR.

This is a case with associated radiologic images for a pediatric patient who developed portomesenteric and splenic vein thrombosis (PMSVT) after Roux-en-Y gastric bypass with subsequent development of portal cavernoma and gallbladder varices (GBV). This case highlights both the importance of post-operative prophylactic anti-coagulation after gastric bypass and detailed imaging following a diagnosis of PMSVT. This case is relevant for pediatric surgeons as they are performing this operation more frequently with the increase in pediatric obesity. Read More

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December 2018
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Editorial Commentary: Dealer's Choice for Arthroscopic Versus Open Lateral Epicondylitis Release? It's Not That Simple.

Authors:
Larry D Field

Arthroscopy 2018 Dec;34(12):3185-3186

Jackson, Mississippi.

The most efficacious treatment for patients with persistent lateral epicondylitis who have not adequately improved despite undergoing extended nonoperative measures may be arthroscopic. One advantage is the capability of the surgeon to fully assess the elbow intra-articularly. Second, the incision is often considered less appealing to both patients and surgeons than portal-site incisions. Read More

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December 2018
1 Read