1,767 results match your criteria Portal Vein Obstruction


The inhibitory role of recombinant P-selectin glycoprotein ligand immunoglobulin G on portal vein thrombosis based on a novel rat model.

Exp Ther Med 2019 May 13;17(5):3589-3597. Epub 2019 Mar 13.

Department of Gastrointestinal Surgery, Huzhou Central Hospital, Zhejiang University Huzhou Hospital, Huzhou, Zhejiang 313000, P.R. China.

The current study aimed to reveal a novel method for constructing a portal vein thrombosis (PVT) model in rats and to evaluate the inhibitory role of recombinant P-selectin glycoprotein ligand immunoglobulin G (rPSGL-Ig) on the formation of PVT. The PVT model was constructed in rats through intermittent portal vein obstruction (IPVO) combined with endangium destruction. A total of 4 mg/kg rPSGL-Ig was intraperitoneally pre-injected into rats 1 h prior to model construction. Read More

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http://dx.doi.org/10.3892/etm.2019.7394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447773PMC

Etiology, presenting features and outcome of children with non-cirrhotic portal vein thrombosis: A multicentre national study.

Dig Liver Dis 2019 Mar 6. Epub 2019 Mar 6.

Paediatric Liver, GI and Transplantation, Hospital Papa Giovanni XXIII Bergamo, Bergamo, Italy. Electronic address:

Objectives: Non-cirrhotic portal vein thrombosis (PVT) is a main cause of portal hypertension in children. We describe the characteristics at presentation and outcome of a cohort of patients with PVT to determine clinical features and predictors of outcome.

Methods: We recorded: (1) Associated factors: prematurity, congenital malformations, neonatal illnesses, umbilical vein catheterization (UVC), deep infections, surgery; (2) congenital and acquired prothrombotic disorders; (3) features at last follow up including survival rate and need for surgery. Read More

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http://dx.doi.org/10.1016/j.dld.2019.02.014DOI Listing
March 2019
1 Read

Spectral Doppler Ultrasound Can Help Diagnose Children With Hepatic Sinusoidal Obstructive Syndrome After Hematopoietic Stem Cell Transplantation.

Ultrasound Q 2019 Mar 27. Epub 2019 Mar 27.

Department of Hematology and Oncology, Rainbow Babies and Children's Hospital, Cleveland, OH.

Background: Hepatic sinusoidal obstruction syndrome (SOS) is a potentially fatal complication after hematopoietic stem cell transplantation (HSCT). Current clinical guidelines state that spectral Doppler changes occur late in the disease, and imaging is only useful for confirming SOS diagnosis.

Objective: Our primary objective was to examine abdominal ultrasound variables as predictors of development of SOS in pediatric HSCT patients. Read More

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http://dx.doi.org/10.1097/RUQ.0000000000000441DOI Listing
March 2019
1 Read

Milestones in the discovery of Budd-Chiari syndrome.

Liver Int 2019 Mar 6. Epub 2019 Mar 6.

Multivisceral Transplant Unit, Department of Surgery, Oncology and Gastroenterology, Padua University Hospital, Padua, Italy.

In 1845, George Budd published a brief report regarding three patients who developed an obstruction of the hepatic veins. The condition has never been reported before, and was related to sepsis and alcoholism. Fifty-three years later, Hans Chiari postulated that syphilis was causing the obstruction of the hepatic veins, and enriched the debate with clinical and pathological correlations. Read More

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http://dx.doi.org/10.1111/liv.14088DOI Listing
March 2019
6 Reads

Current knowledge in pathophysiology and management of Budd-Chiari syndrome and non-cirrhotic non-tumoral splanchnic vein thrombosis.

J Hepatol 2019 Feb 26. Epub 2019 Feb 26.

Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic de Barcelona, IDIBAPS, CIBERehd, European Reference Network for Rare Vascular Liver Diseases. Universitat de Barcelona, Spain. Electronic address:

Budd-Chiari Syndrome (BCS) and non-cirrhotic non-tumoral portal vein thrombosis (NCPVT) are two rare disorders, with several similarities that are categorized under the term splanchnic vein thrombosis. Both disorders are frequently associated with an underlying pro-thrombotic disorder. They can cause severe portal hypertension and usually affect oung patients, negatively influencing life expectancy when the diagnosis and treatment is not done at an early stage. Read More

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http://dx.doi.org/10.1016/j.jhep.2019.02.015DOI Listing
February 2019
2 Reads

Air in Where? Extensive Pneumatosis with Portal Venous, Mesenteric, and Splenic Gas.

Am Surg 2019 Feb;85(2):e69-e70

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February 2019
5 Reads

CT Image of Extrahepatic Portal Vein Obstruction.

Intern Med 2019 Feb 25. Epub 2019 Feb 25.

Departments of Pediatrics, Faculty of Medicine, Saga University, Japan.

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http://dx.doi.org/10.2169/internalmedicine.2297-18DOI Listing
February 2019

Endovascular treatment of a splenic vein aneurysm through a transhepatic approach.

Diagn Interv Radiol 2019 Mar;25(2):166-168

Departments of Interventional Radiology, Clínica Universidad de Navarra, Pamplona, Spain.

Aneurysms of the portal vein and its branches have been rarely described. Their natural history is unknown although large ones (>3 cm in diameter) have been reported to cause rupture, thrombosis, duodenal or biliary obstruction, inferior vena cava compression and/or portal hypertension. We report the case of an incidentally diagnosed 4. Read More

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http://dx.doi.org/10.5152/dir.2019.18057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411270PMC
March 2019
5 Reads

Hepatotoxicities Induced by Neoadjuvant Chemotherapy in Colorectal Cancer Liver Metastases: Distinguishing the True From the False.

Clin Med Insights Oncol 2019 22;13:1179554918825450. Epub 2019 Jan 22.

Digestive Tumours Unit, Institut Bergonié, Bordeaux, France.

Background: Pre-operative chemotherapy for colorectal liver metastasis (CRLM) is thought to be the cause of hepatotoxicity of non-tumoural parenchyma. Studies on hepatotoxicity are contradictory. We investigated the impact of a single-line pre-operative chemotherapy on non-tumoural liver analysed by an expert hepatico-pancreatico-biliary pathologist, and the consequences on surgical outcomes. Read More

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http://dx.doi.org/10.1177/1179554918825450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348554PMC
January 2019
2 Reads

Portal vein pseudoaneurysm secondary to pancreatic lymphoma and biliary stent insertion: a rare cause of haemobilia.

CVIR Endovasc 2018 28;1(1). Epub 2018 Jun 28.

2University College London Hospital, Euston Road, London, NW1 2BU UK.

Background: Haemobilia, defined as bleeding from the biliary tree, is a rare entity. The most common cause of haemobilia is iatrogenic trauma, which accounts for 70% of cases. Pseudoaneurysms of the portal vein are an extremely rare cause of haemobilia with only four reported cases to date. Read More

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http://dx.doi.org/10.1186/s42155-018-0011-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319504PMC
June 2018
2 Reads

Pneumatosis intestinalis and hepatic portal venous gas associated with gas-forming bacterial translocation due to postoperative paralytic ileus: A case report.

Medicine (Baltimore) 2019 Jan;98(2):e14079

Department of Diagnostic Pathology.

Rationale: Pneumatosis intestinalis (PI) and hepatic portal venous gas (HPVG) are rare but potentially lethal conditions in which gas pathologically accumulates in the portal vein and intestinal wall, respectively. Proposed mechanisms include flatus escaping through an injured intestinal mucosa into the submucosa and thence into the portal venous system, or bacterial translocation (BT) of gas-forming enteric microorganisms from the gut into and through the intestinal wall to other organs. However, there has been no clear histopathological evidence to support these hypotheses. Read More

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http://dx.doi.org/10.1097/MD.0000000000014079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336625PMC
January 2019
12 Reads

Role of Virtual Touch Tissue Imaging Quantification in the Assessment of Hepatic Sinusoidal Obstruction Syndrome in a Rat Model.

J Ultrasound Med 2018 Dec 17. Epub 2018 Dec 17.

Departments of Ultrasound, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing, China.

Objectives: To investigate the value of liver stiffness in rats with various degrees of hepatic sinusoidal obstruction syndrome (HSOS) induced by monocrotaline by comparing liver histopathologic findings.

Methods: Seventy rats were randomly divided into a control group (n = 10), a low-dose monocrotaline group (n = 30), and a high-dose monocrotaline group (n = 30). After successful modeling, the liver shear wave velocity (SWV) by Virtual Touch tissue imaging quantification (Siemens Medical Solutions, Mountain View, CA) and the alanine aminotransferase (ALT), aspartate aminotransferase (AST), and total bilirubin levels of the groups were obtained on days 3 and 5, and the intergroup differences were compared. Read More

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http://doi.wiley.com/10.1002/jum.14893
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http://dx.doi.org/10.1002/jum.14893DOI Listing
December 2018
13 Reads

Rat models of high risk colorectal anastomoses 1.

Acta Cir Bras 2018 Oct;33(10):914-923

PhD, Full Professor, Head, Centre of Experimental Surgical, Coordinator of Postgraduate Program in Surgical Science, Department of Surgery, School of Medicine, UFRJ, Rio de Janeiro-RJ, Brazil. Intellectual, conception and design of the study; analysis and interpretation of data; manuscript preparation; critical revision.

Purpose: To evaluate the most frequent surgical techniques of high-risk colorectal anastomoses in rats.

Methods: Wistar rats were enrolled in three different models comprising inflammatory (TNBS enema), vascular (portal vein occlusion) or obstructive (a non-ischemic constricting ring) mechanisms associated with colonic anastomosis that had accomplished after these former lesions. Histological analyses (Hematoxylin and eosin and Picrosirius red) were performed. Read More

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http://dx.doi.org/10.1590/s0102-865020180100000006DOI Listing
October 2018
17 Reads

Chylothorax after hepatectomy: a case report.

J Med Case Rep 2018 Nov 26;12(1):347. Epub 2018 Nov 26.

Department of Surgery, Yachiyo Hospital, 2-2-7, Sumiyoshi-cho, Anjo-shi, Aichi, 446-8510, Japan.

Background: Chylothorax is the accumulation of chyle within the pleural space. Chylothorax can occur as a complication after multiple different types of surgery, most frequently after thoracic surgery, albeit with an incidence rate of less than 1%. Chylothorax after abdominal surgery is extremely rare, and there are only a few case reports. Read More

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http://dx.doi.org/10.1186/s13256-018-1882-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260677PMC
November 2018
2 Reads

Multimodality imaging of the Meso-Rex bypass.

Abdom Radiol (NY) 2019 Apr;44(4):1379-1394

Diagnostic and Therapeutic Services Department, IRCCS-ISMETT (Mediterranean Institute for Transplantation and Advanced Specialized Therapies), Via Ernesto Tricomi 5, 90127, Palermo, Italy.

Extrahepatic portal vein obstruction (EHPVO) is the most common cause of upper gastrointestinal bleeding in children. It is defined as thrombosis of the extrahepatic portal vein with or without extension to the intrahepatic portal veins. The Meso-Rex shunt is the gold standard treatment in children with favorable anatomy since it restores physiological portal liver reperfusion. Read More

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http://dx.doi.org/10.1007/s00261-018-1836-1DOI Listing
April 2019
32 Reads

Recanalization of Chronic Extrahepatic Portal Vein Obstruction in Pediatric Patients Using a Minilaparotomy Approach.

J Pediatr Gastroenterol Nutr 2019 Mar;68(3):384-388

Department of Surgery, University of Minnesota, Masonic Children's Hospital, Minneapolis, MN.

Purpose: Extrahepatic portal vein obstruction (EHPVO) is the most frequent cause of portal hypertension in children. Some patients are not amenable to meso-Rex bypass and alternative surgeries do not restore physiologic flow. We aim to demonstrate the feasibility and safety of minilaparotomy for recanalization of chronic EHPVO. Read More

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http://dx.doi.org/10.1097/MPG.0000000000002206DOI Listing
March 2019
4 Reads

Initial experience with minimally invasive extended pancreatectomies for locally advanced pancreatic malignancies: Report of six cases.

J Minim Access Surg 2018 Nov 9. Epub 2018 Nov 9.

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital; Duke-Nus Medical School, Singapore.

Background: Recently, there have been several reports on minimally-invasive surgery for extended pancreatectomy (MIEP) in the literature. However, to date, only a limited number of studies reporting on the outcomes of MIEP have been published. In the present study, we report our initial experience with MIEP defined according to the latest the International Study Group for Pancreatic Surgery (ISPGS) guidelines. Read More

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http://dx.doi.org/10.4103/jmas.JMAS_69_18DOI Listing
November 2018
18 Reads

Excellent long-term outcomes of endovascular treatment in budd-chiari syndrome with hepatic veins involvement: A STROBE-compliant article.

Medicine (Baltimore) 2018 Oct;97(43):e12944

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University.

This study aimed to evaluate the long-term efficacy and safety of percutaneous transhepatic balloon angioplasty (PTBA) and transjugular intrahepatic portosystemic stent-shunt (TIPSS) in the treatment of Budd-Chiari syndrome (BCS) with hepatic veins involvement. Between June 2008 and August 2016, a total of 60 BCS patients with hepatic vein involvement in our department were enrolled in this study. Thirty-three cases underwent hepatic vein balloon angioplasty in PTBA Group and 27 cases underwent TIPSS. Read More

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http://dx.doi.org/10.1097/MD.0000000000012944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221688PMC
October 2018
19 Reads

Portal Cavernoma Cholangiopathy: Histologic Features and Differential Diagnosis.

Am J Clin Pathol 2019 Feb;151(3):255-262

Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY.

Objectives: Portal cavernoma cholangiopathy (formerly portal biliopathy) is a type of biliary injury that occurs in association with a portal vein thrombus or cavernoma. Although the radiographic features of portal cavernoma cholangiopathy have been enumerated in the literature, its histologic features have not been described in detail.

Methods: We describe the histologic findings in liver specimens from three patients with radiologically confirmed portal cavernoma cholangiopathy. Read More

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http://dx.doi.org/10.1093/ajcp/aqy132DOI Listing
February 2019
5 Reads

Percutaneous Recanalization of Anastomotic Portal Vein in a Pediatric Patient After Liver Transplant Without Any Recognizable Portal Vein Remnant on Imaging.

Exp Clin Transplant 2018 Oct 19. Epub 2018 Oct 19.

From the Department of Interventional Radiology, Sir Gangaram Hospital, New Delhi, India.

In patients with complete portal vein thrombosis, the main portal vein is obstructed, resulting in development of hepatopetal collateral vessels. In cases of complete portal vein thrombosis, interventional procedures are challenging, with the greatest difficulty in the form of passing the guide wire across the level of obstruction. A recognizable main portal vein remnant has been deemed as a mandatory criterion in previous reports. Read More

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http://dx.doi.org/10.6002/ect.2017.0326DOI Listing
October 2018
3 Reads

Doppler ultrasound predictors of transplant hepatic venous outflow obstruction in pediatric patients.

Pediatr Transplant 2018 12 19;22(8):e13310. Epub 2018 Oct 19.

Pediatric Transplantation, Seattle Children's Hospital and University of Washington, Seattle, Washington.

Objective: To investigate Doppler US and catheter venogram correlates to improve detection of transplant HVOO and avoid unnecessary invasive imaging procedures.

Materials And Methods: A retrospective review was performed in all pediatric OLT patients undergoing catheter venography of the hepatic veins between 2007 and 2017 at a single large tertiary pediatric liver transplant institution.

Results: Forty-four transplant hepatic venograms in 32 OLT patients were included (mean 1. Read More

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http://dx.doi.org/10.1111/petr.13310DOI Listing
December 2018
3 Reads
1.630 Impact Factor

Pulmonary Arterial Pressure Management Based on Oral Medicine for Pediatric Living Donor Liver Transplant With Portopulmonary Hypertension.

Transplant Proc 2018 Nov 15;50(9):2614-2618. Epub 2018 Mar 15.

Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Suita, Japan.

Pediatric living donor liver transplantation (LDLT) in patients with advanced portopulmonary hypertension (PoPH) is associated with poor prognoses. Recently, novel oral medications, including endothelin receptor antagonists (ERAs), phosphodiesterase 5 (PDE5) inhibitors, and oral prostacyclin (PGI2) have been used to treat PoPH. Pediatric patients with PoPH who underwent LDLT from 2006 to 2016 were enrolled. Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.03.068DOI Listing
November 2018
2 Reads

Evaluation of Splenic Stiffness in Patients of Extrahepatic Portal Vein Obstruction Using 2D Shear Wave Elastography: Comparison with Intra-Operative Portal Pressure.

J Clin Exp Hepatol 2018 Sep 30;8(3):250-255. Epub 2017 Dec 30.

Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.

Background/aims: To compare splenic stiffness (SS) with intra-operative portal pressures (PPs) in patients of extrahepatic portal vein obstruction (EHPVO).

Methods: Twenty-one patients (14 males; 7 females) of mean age 20.4 years with clinical and sonographic diagnosis of EHPVO were included in this approved prospective study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09736883173050
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http://dx.doi.org/10.1016/j.jceh.2017.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175726PMC
September 2018
15 Reads

Prognostic Impact of Portal System Invasion in Pancreatic Cancer Based on Image Classification.

Pancreas 2018 Nov/Dec;47(10):1350-1356

Department of Surgery and Science, Graduate School of Medicine and Pharmaceutical Sciences, Toyama University, Toyama, Japan.

Objectives: This study aimed to clarify the correlation between image classification and the pathological degree of portal system invasion (PSI) and to evaluate the prognostic impact of PSI in pancreatic cancer (PC).

Methods: Pancreatic cancer patients with surgical resections (head, n = 244; body and tail, n = 80) were enrolled in this study.

Results: Based on imaging findings, portal vein (PV) invasion was classified as type A (absent), B (unilateral narrowing), C (bilateral narrowing), or D (stenosis or obstruction with collaterals). Read More

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http://Insights.ovid.com/crossref?an=00006676-900000000-9851
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http://dx.doi.org/10.1097/MPA.0000000000001186DOI Listing
March 2019
7 Reads

Novel technique for pediatric living donor liver transplantation in patients with portal vein obstruction: The "pullout technique".

Pediatr Transplant 2018 12 2;22(8):e13297. Epub 2018 Oct 2.

Organ Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.

PV hypoplasia may increase the risk of posttransplant complications, especially when it extends to near the SMV and SpV junction. We described our experience of 10 pediatric cases of PV hypoplasia/thrombus in which the pullout technique was required for PV reconstruction. There were five male and five female patients. Read More

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http://doi.wiley.com/10.1111/petr.13297
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http://dx.doi.org/10.1111/petr.13297DOI Listing
December 2018
4 Reads

Portal Vein Stenting for Portal Vein Stenosis After Pancreatoduodenectomy: A Case Report.

Yonago Acta Med 2018 Sep 26;61(3):182-186. Epub 2018 Sep 26.

Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8504, Japan.

Portal vein stenosis, which results in serious clinical conditions such as gastrointestinal variceal bleeding and liver failure, is caused by hepatobiliary pancreatic cancer or major postoperative complications after hepatobiliary pancreatic surgery. In recent years, portal vein stenting under interventional radiology has been applied as a more useful treatment method for portal vein stenosis than invasive surgery. We herein report the successful use of a vascular stent for portal vein stenosis after pancreatoduodenectomy. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158355PMC
September 2018
31 Reads

Cirrhosis and Portal Hypertension in the Pediatric Population.

Clin Liver Dis 2018 11 22;22(4):735-752. Epub 2018 Aug 22.

Division of Pediatric Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, 225 East Chicago Avenue, Box #65, Chicago, IL 60611, USA. Electronic address:

Cirrhosis is a complex process in which the architecture of the liver is replaced by structurally abnormal nodules due to cirrhosis. Cirrhosis frequently leads to the development of portal hypertension. In children, portal hypertension may be caused by a wide range of etiologies, including extrahepatic portal vein obstruction, biliary atresia, alpha 1 antitrypsin deficiency, and autoimmune hepatitis. Read More

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http://dx.doi.org/10.1016/j.cld.2018.06.007DOI Listing
November 2018
19 Reads

Cholangiopathy in children with extrahepatic portal venous obstruction.

J Hepatobiliary Pancreat Sci 2018 Oct 16;25(10):440-447. Epub 2018 Oct 16.

Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226014, India.

Background: Portal cavernoma cholangiopathy (PCC), a surgical-endoscopic dilemma, has not been studied comprehensively, more so in children. Our study aimed to evaluate PCC in children using a combination of magnetic resonance cholangiography-portovenography (MRC-MRPV) and endoscopic ultrasonography (EUS).

Methods: In this prospective cross-sectional study, recruited children with extrahepatic portal venous obstruction (EHPVO) underwent MRC-MRPV and radial array EUS. Read More

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http://dx.doi.org/10.1002/jhbp.582DOI Listing
October 2018
15 Reads

Intestinal obstruction with a twist: a rare case of congenital portal vein aneurysm causing intestinal obstruction.

BMJ Case Rep 2018 Sep 21;2018. Epub 2018 Sep 21.

Department of Pediatric surgery, Christian Medical College and Hospital, Vellore, Tamilnadu, India.

Bilious vomiting is often a presenting feature of upper intestinal obstruction in newborn. We present a case of intestinal obstruction in a newborn baby caused by abnormal vascular band arising from portal vein aneurysm in association with a midgut volvulus. Congenital anomalies of portovenous system are very rare, and it usually presents with portal hypertension in late infancy or childhood. Read More

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http://dx.doi.org/10.1136/bcr-2018-225689DOI Listing
September 2018
6 Reads

The effects of Kasai procedure on living donor liver transplantation for children with biliary atresia.

J Pediatr Surg 2018 Aug 29. Epub 2018 Aug 29.

Tianjin First Center Hospital, Key Laboratory of Organ Transplant of Tianjin, China. Electronic address:

Objective: To evaluate the effects of Kasai procedure (hepatic portoenterostomy) on living donor liver transplantation (LDLT) for children with biliary atresia (BA).

Methods: From January 2006 to January 2014, 150 children with BA were treated with LDLT in China. The children were categorized into pre-Kasai and non-Kasai groups, based on whether they had previously undergone Kasai procedure. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.07.022DOI Listing
August 2018
5 Reads
1.310 Impact Factor

Measurement of splenic stiffness by 2D-shear wave elastography in patients with extrahepatic portal vein obstruction.

Br J Radiol 2018 Dec 18;91(1092):20180401. Epub 2018 Sep 18.

1 Department of Radiodiagnosis, All India Institute of Medical Sciences , New Delhi , India.

Objective:: To assess the accuracy of splenic stiffness (SS) measured by 2D-shear wave elastography (SWE) for predicting variceal bleeding in the patients with extrahepatic portal vein obstruction (EHPVO).

Methods:: 52 patients with EHPVO (mean age: 22.29 years; 26 each males and females) were included in the study after obtaining approval from the institute ethics committee. Read More

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http://dx.doi.org/10.1259/bjr.20180401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319854PMC
December 2018
23 Reads

Contrast-enhanced Computed Tomography Imaging of Splenic Artery Aneurysms and Pseudoaneurysms: A Single-center Experience.

J Clin Imaging Sci 2018 24;8:37. Epub 2018 Aug 24.

Department of Gastroenterology, Christian Medical College, Vellore, Tamil Nadu, India.

Aim: The aim of our study was to evaluate the computed tomography (CT) imaging features of splenic artery aneurysm and pseudoaneurysm and to identify the disease conditions related to the same. We also wanted to ascertain any relationship between these associated disease conditions and the imaging features of the aneurysms.

Materials And Methods: This retrospective study included patients diagnosed to have splenic artery aneurysms on contrast-enhanced CT examination between January 2001 and January 2016. Read More

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http://dx.doi.org/10.4103/jcis.JCIS_21_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118105PMC
August 2018
6 Reads

Gastric varices and splenic vein obstruction during steroid treatment for autoimmune pancreatitis: A case report and literature review.

Medicine (Baltimore) 2018 Aug;97(34):e11940

Section of Hospital Medicine, Department of Medicine, University of Chicago, Chicago, IL.

Rationale: Few cases of autoimmune pancreatitis (AIP) complicated by gastric varices, in the absence of splenic vein obstruction, have been described in the medical literature. The findings in this case parallel those of 3 previously described cases from Japan and support a pathologic explanation for the evolution of gastric varices in relation to early splenomegaly and the role of steroid therapy for AIP.

Patient Concerns: A 50-year-old male with a history of transfusion-requiring erosive gastritis and recently diagnosed AIP on steroid therapy for 2 weeks presented with a 2-day history of lightheadedness, abdominal pain, and melena. Read More

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http://dx.doi.org/10.1097/MD.0000000000011940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112881PMC
August 2018
4 Reads

Liver hypertrophy: Underlying mechanisms and promoting procedures before major hepatectomy.

J Visc Surg 2018 Oct 17;155(5):393-401. Epub 2018 Aug 17.

Department of Digestive and Hepatobiliary Surgery, Hôpital Estaing, CHU Clermont-Ferrand, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France; UMR Auvergne UMR 6602 UCA/CNRS/SIGMA, Clermont-Ferrand Faculty of Medicine, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France.

Various procedures can promote hypertrophy of the future liver remnant (FLR) before major hepatectomy to prevent postoperative liver failure. The pathophysiological situation following portal vein embolization (PVE), hepatic artery ligation/embolization or hepatectomy remains unclear. On one hand, the main mechanisms of hepatic regeneration appear to be driven by hepatic hypoxia (involving the hepatic arterial buffer response), an increased portal blood flow inducing shear stress and the involvement of several mediators (inflammatory cytokines, vasoregulators, growth factors, eicosanoids and several hormones). Read More

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http://dx.doi.org/10.1016/j.jviscsurg.2018.03.005DOI Listing
October 2018
2 Reads

Management of Portal Hypertension in the Pediatric Population: A Primer for the Interventional Radiologist.

Semin Intervent Radiol 2018 Aug 6;35(3):160-164. Epub 2018 Aug 6.

Department of Interventional Radiology, Northwestern Memorial Hospital, Chicago, Illinois.

Interventional radiology's role in the management of portal hypertension in the pediatric population differs from the management of adult portal hypertension. In the pediatric population, portal hypertension is frequently secondary to thrombosis and cavernous transformation of the extrahepatic portion of the portal vein. Transjugular intrahepatic portosystemic shunt can be utilized to manage portal hypertension in children with intrinsic liver disease that results in cirrhosis and portal hypertension, and is often used as a bridge to transplant. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1660794
Publisher Site
http://dx.doi.org/10.1055/s-0038-1660794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078695PMC
August 2018
11 Reads

Long-Term Results after Diversion Surgery in Extrahepatic Portal Vein Obstruction.

Eur J Pediatr Surg 2019 Feb 7;29(1):23-27. Epub 2018 Aug 7.

Department of Pediatric Surgery, Hospital Universitario La Paz, Madrid, Spain.

Aim:  Extrahepatic portal vein obstruction (EHPVO) is a frequent cause of noncirrhotic portal hypertension in children. The aim of this study is to analyze long-term results after diversion surgery.

Patients And Methods:  Retrospective review of EHPVO patients who underwent diversion surgery analyzing number of platelets, leukocytes, prothrombin activity, splenomegaly, and gastrointestinal bleeding 10 years after surgery. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1668147
Publisher Site
http://dx.doi.org/10.1055/s-0038-1668147DOI Listing
February 2019
9 Reads

Acute intestinal ischaemia from a portal vein thrombosis in a young female smoker on an oral contraceptive.

BMJ Case Rep 2018 Aug 4;2018. Epub 2018 Aug 4.

Department of Gastroenterology, US Army Brooke Army Medical Center, Fort Sam Houston, Texas, USA.

We report the case of a 23-year-old woman who presented with bloody diarrhoea and multiple syncopal events. While the initial diagnosis clinically appeared to be inflammatory bowel disease, she was found to have a portal vein thrombosis (PVT) on MR cholangiopancreatography and acute intestinal ischaemia on colonic biopsy. The aetiology of this patient's PVT is attributed to her acquired prothrombotic state from an estrogen-containing contraceptive pill in conjunction with regular tobacco use. Read More

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http://dx.doi.org/10.1136/bcr-2018-225135DOI Listing
August 2018
4 Reads

Ultrasonography in Liver Vascular Disease.

Ultraschall Med 2018 Aug 2;39(4):382-405. Epub 2018 Aug 2.

Servicio de Radiodiagnóstico, Hospital Clinic, Barcelona, Spain.

Vascular liver diseases include a heterogeneous group of disorders affecting the micro- and the macro-circulation of the liver. Thrombosis and obstruction of the inflow (portal vein) and/or outflow venous system (Budd-Chiari syndrome), spontaneous porto-systemic shunts, diseases affecting the sinusoids, and hepatic vascular malformations are the most important vascular liver diseases. Thrombosis of the portal venous system and of the hepatic venous system occur most commonly and are potentially life-threatening conditions, while congenital and acquired pro-thrombotic diseases are major causal factors, together with local factors triggering thrombotic events. Read More

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http://dx.doi.org/10.1055/a-0647-1658DOI Listing
August 2018
11 Reads

[Observation of the efficacy of biological patch in hybrid technique for incisional herniorrhaphy: 5-year follow-up results from a single center].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Jul;21(7):766-771

Department of Gastrointestinal Surgery, Hernia and Abdominal Wall Surgery, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080,

Objective: To observe the safety and efficacy of biological patch (Biodesign Surgisis mesh, SIS) in hybrid technique for incisional herniorrhaphy.

Methods: Clinical and follow-up data of 14 incisional hernia patients who underwent incisional herniorrhaphy with hybrid technique, using porcine small intestinal submucosa acellular matrix patch, at the First Affiliated Hospital of Sun Yat-sen University from January 1, 2012 to June 31, 2016 were analyzed retrospectively. This Biodesign Surgisis patch for incisional hernia is produced by the Cook company in the United States. Read More

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July 2018
7 Reads

Long-term outcomes of transmesenteric portal vein recanalization for the treatment of chronic portal vein thrombosis after pediatric liver transplantation.

Am J Transplant 2018 Sep 13;18(9):2220-2228. Epub 2018 Aug 13.

Liver Transplantation Unit, A. C. Camargo Cancer Center Hospital, São Paulo, Brazil.

Portal vein thrombosis (PVT) may occur at any time following liver transplantation. We describe our experience with portal vein recanalization in cases of thrombosis after liver transplantation. Twenty-eight children (5%) out of 566 liver transplant recipients underwent portal vein recanalization using a transmesenteric approach. Read More

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http://dx.doi.org/10.1111/ajt.15022DOI Listing
September 2018
2 Reads

[Current status and prospects of integrated traditional Chinese and Western medicine for treatment of portal hypertension].

Zhonghua Gan Zang Bing Za Zhi 2018 Apr;26(4):249-253

Center of Therapeutic Research for Hepatocellular Carcinoma, The 302nd Hospital, Beijing 100039, China.

Portal hypertension refers to a series of clinical manifestations caused by elevated pressure of the portal vein system, which can cause portal hypertension by causing portal venous obstruction and / or increased blood flow. A typical clinical manifestation in patients with decompensated cirrhosis is portal hypertension. A severe complication of portal hypertension is esophagogastric varices bleeding, refractory ascites, and hepatic encephalopathy. Read More

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http://doi.med.wanfangdata.com.cn/10.3760/cma.j.issn.1007-34
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http://dx.doi.org/10.3760/cma.j.issn.1007-3418.2018.04.003DOI Listing
April 2018
6 Reads

Surgical Decision Making in Preduodenal Portal Vein: Report of Two Cases in Neonates.

European J Pediatr Surg Rep 2018 Jan 5;6(1):e40-e42. Epub 2018 Jul 5.

Department of Pediatric Surgery, Chelsea and Westminster Hospital NHS Foundation Trust, London, United Kingdom of Great Britain and Northern Ireland.

Preduodenal portal vein (PDPV) is a rare anomaly that can cause duodenal obstruction. PDPV is associated with other congenital anomalies, mainly cardiac and gastrointestinal. Treatment usually consists of bypassing the obstruction by duodenoduodenostomy. Read More

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http://dx.doi.org/10.1055/s-0038-1661409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033610PMC
January 2018
3 Reads

The Abernethy malformation with inferior caval vein hypoplasia: a tailored technique for transcatheter closure and an insight into embryological perspective.

Cardiol Young 2018 Sep 6;28(9):1169-1171. Epub 2018 Jul 6.

Department of Pediatric Cardiology,Institute of Cardio Vascular Diseases,Madras Medical Mission,Chennai,India.

Abernethy malformations manifest as hepatopulmonary syndrome, pulmonary vasculopathy, or encephalopathy. A novel intervention in a child with portosystemic shunt and inferior caval vein hypoplasia led to complete normalisation of hypoxia and relief of obstruction in the inferior caval vein. Embryological explanations of venous anomalies may indicate that inferior caval vein anomalies are frequent but under-recognised in patients with Abernethy malformation. Read More

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http://dx.doi.org/10.1017/S1047951118000884DOI Listing
September 2018
23 Reads

Budd-Chiari syndrome has different presentations and disease severity during adolescence.

Hepatol Int 2018 Nov 3;12(6):560-566. Epub 2018 Jul 3.

Department of Gastroenterology, KEM Hospital and Seth GS Medical College, Multistory Building, 11th floor, Parel, Mumbai, Maharashtra, 400012, India.

There are limited data on clinical profile of adolescent patients with Budd-Chiari syndrome (BCS). We studied clinical, radiological, thrombophilia profile and treatment outcomes in adolescent patients with BCS.

Methods: Forty-three consecutive patients of BCS with onset of symptoms during adolescence (10-19 years) were enrolled in the study. Read More

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http://dx.doi.org/10.1007/s12072-018-9880-zDOI Listing
November 2018
19 Reads

Portal hypertension and hypersplenism in extrahepatic portal venous obstruction: Are they related?

Indian J Gastroenterol 2018 May 23;37(3):202-208. Epub 2018 Jun 23.

Department of Gastrointestinal Surgery and Liver Transplantation, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110 029, India.

Background And Aims: Portal hypertension (PHT) due to extrahepatic portal venous obstruction (EHPVO) is common in developing countries. Hypersplenism is a near-constant feature of EHPVO, but its significance, unlike in cirrhotics, is unknown. We aimed to study the relationship between hypersplenism and the severity of PHT in patients with EHPVO. Read More

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http://dx.doi.org/10.1007/s12664-018-0864-7DOI Listing
May 2018
4 Reads

Rectal varices due to chronic inferior mesenteric vein thrombosis caused by external compression in a large hiatus hernia containing the pancreas.

Ann R Coll Surg Engl 2018 Sep 18;100(7):e171-e173. Epub 2018 Jun 18.

Department of General Surgery, Stepping Hill Hospital , Stockport , UK.

A 79-year-old woman presented with a large fresh rectal bleed. Computed tomography revealed that she had a large type IV hiatus hernia, which contained the stomach and pancreas. Compression of the inferior mesenteric vein and splenic vein had led to thrombosis within these vessels and retrograde flow within the inferior mesenteric vein. Read More

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http://dx.doi.org/10.1308/rcsann.2018.0083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214064PMC
September 2018
13 Reads

Postoperative enlargement and prognostic effects of portal venous bypass grafts in children undergoing Rex shunt.

J Vasc Surg Venous Lymphat Disord 2018 Nov 22;6(6):742-747. Epub 2018 May 22.

Department of Pediatric Surgery, Beijing United Family Hospital, Beijing, People's Republic of China; Department of Pediatric Surgery, Monash Children's Hospital, Monash University, Melbourne, Victoria, Australia.

Objective: Patency of the bypass vein after a Rex shunt is an important indicator of prognosis. However, there is no report about the change of caliber of the bypass vein after a Rex shunt. The aim of this study was to identify postoperative changes of the bypass vein and to assess the relationship with prognosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S2213333X183013
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http://dx.doi.org/10.1016/j.jvsv.2018.01.020DOI Listing
November 2018
7 Reads

[Sinusoidal obstruction syndrome induced by monocrotaline in a large animal experiment - a pilot study].

Rozhl Chir Spring 2018;97(5):214-221

Introduction: Sinusoidal obstruction syndrome (SOS) is a disease which is caused by toxic injury to hepatic sinusoids. This syndrome is most frequently caused by myeloablative radiochemotherapy in patients before hematopoietic stem cells transplantation and also by oxaliplatin mainly in patients with colorectal liver metastases. The aim of this study was to establish a large animal model of SOS, which would enable further study of this disease and facilitate translation of experimental outcomes into human medicine. Read More

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May 2018
1 Read