521 results match your criteria Poroma

Eccrine Poroma Arising within Nevus Sebaceous.

Ann Dermatol 2020 Dec 11;32(6):516-518. Epub 2020 Nov 11.

Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, Korea.

Secondary neoplasms in nevus sebaceous can develop during adolescence and adulthood. Trichoblastoma and syringocystadenoma papilliferum are the most common benign neoplasms, but poroma is rarely reported. A 28-year-old female presented with an asymptomatic mass on the scalp. Read More

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December 2020

A Case of Eccrine Poromatosis in a Patient with a History of Chemotherapy Due to Stomach Cancer.

Ann Dermatol 2020 Oct 29;32(5):422-425. Epub 2020 Sep 29.

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

An eccrine poroma (EP) is a benign adnexal tumor that typically presents as a single lesion. Eccrine poromatosis defined as multiple EPs is an uncommon presentation. A 54-year-old male had undergone operation for stomach cancer 10 years prior and insisted that he had also taken adjuvant chemotherapy. Read More

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October 2020

Eccrine Porocarcinoma: A Multicenter Retrospective Study with Review of the Literatures Reported in Korea.

Ann Dermatol 2020 Jun 24;32(3):223-229. Epub 2020 Apr 24.

Department of Dermatology, College of Medicine, Korea University, Seoul, Korea.

Background: Eccrine porocarcinoma (EPC) is a rare malignant cutaneous adnexal tumor. Other than several scattered case reports, no comprehensive review on EPC has been conducted in Korea.

Objective: To clinicopathologically review all EPC cases from our institutions as well as those reported in Korea. Read More

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Genetic analyses of a secondary poroma and trichoblastoma in a HRAS-mutated sebaceous nevus.

J Dermatol 2021 Apr 27. Epub 2021 Apr 27.

Department of Dermatology, Sapporo Medical University School of Medicine, Sapporo, Japan.

A sebaceous nevus is a congenital skin hamartoma caused by postzygotic HRAS or KRAS mosaic mutations. With age, affected individuals may develop secondary tumors within a sebaceous nevus. RAS mutations are harbored from the onset of sebaceous nevus, and further mutations can be expected to be required in order to explain the initiation of secondary tumors. Read More

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Magnetic Resonance Imaging Characteristics of Poroma and Porocarcinoma.

J Comput Assist Tomogr 2021 Mar 12. Epub 2021 Mar 12.

From the Departments of Radiology Pathology Dermatology, Gifu University, Gifu, Japan.

Purpose: The purpose of this study was to evaluate magnetic resonance (MR) imaging findings of poroma and porocarcinoma.

Methods: Six patients (3 male, 3 female; age range, 40-84 years; mean age, 61 years) with histologically confirmed skin appendage tumors with apocrine and eccrine differentiation (2 poromas and 4 porocarcinomas) were enrolled. All patients underwent preoperative MR imaging and the MR images were retrospectively reviewed. Read More

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Diagnostic features of a non-pigmented eccrine poroma with a collarette: Histopathological and dermoscopic correlation.

Tomoaki Takada

Clin Case Rep 2021 Mar 9;9(3):1601-1604. Epub 2021 Feb 9.

Sumikawa Takada Dermatology Clinic Sapporo Hokkaido Japan.

This is a case that emphasized the need for detailed observation of the entire lesion in dermoscopic examination. Novel dermoscopic findings within a collarette. Read More

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NUT Is a Specific Immunohistochemical Marker for the Diagnosis of YAP1-NUTM1-rearranged Cutaneous Poroid Neoplasms.

Am J Surg Pathol 2021 Feb 24. Epub 2021 Feb 24.

*CARADERM, French Network of Rare Cutaneous Cancer †Department of Pathology, Timone University Hospital ‡Aix Marseille University, INSERM, MMG, Marseille §Department of Pathology, Trousseau University Hospital, Tours ∥Department of Pathology, Cochin Hospital, AP-HP Paris University Center ¶University of Paris #Molecular Oncology Unit ∥∥Department of Pathology, Hospital Saint-Louis, AP-HP **INSERM, U976 HIPI, Paris ††Department of Dermatology, Lyon-Sud Hospital ‡‡Department of Biopathology, Léon Bérard Centre, Cypath, Lyon §§Department of Pathology, Bordeaux University Hospitals, Pessac ¶¶Department of Pathology, University Hospital of Poitiers ##LITEC EA 4331, B36, Poitiers, France.

YAP1-NUTM1 fusion transcripts have been recently reported in poroma and porocarcinoma. NUTM1 translocation can be screened by nuclear protein in testis (NUT) immunohistochemistry in various malignancies, but its diagnostic performance has not been thoroughly validated on a large cohort of cutaneous epithelial neoplasms. We have evaluated NUT immunohistochemical expression in a large cohort encompassing 835 cases of various cutaneous epidermal or adnexal epithelial neoplasms. Read More

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February 2021

Pigmented poroma showing unique pineapple-like dermoscopic appearance with target network-like structure.

Int J Dermatol 2021 Mar 17. Epub 2021 Mar 17.

The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, China.

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Poroid adnexal skin tumors with YAP1 fusions exhibit similar histopathologic features: A series of six YAP1-rearranged adnexal skin tumors.

J Cutan Pathol 2021 Mar 11. Epub 2021 Mar 11.

Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Background: Adnexal skin tumors are diagnostically challenging with few known molecular signatures. Recently, however, YAP1-MAML2 and YAP1-NUTM1 fusions were identified in poroid adnexal skin tumors.

Methods: Herein, we subjected eight poroid adnexal skin tumors (three poromas and five porocarcinomas) to fusion gene analysis by whole transcriptome sequencing and next-generation DNA sequencing analysis. Read More

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Rare case of eccrine poroma in recessive dystrophic epidermolysis bullosa.

Int J Dermatol 2021 Mar 2. Epub 2021 Mar 2.

Department of Infectious Diseases, Dermatology, Diagnostic Imaging and Radiotherapy, São Paulo State University (UNESP), Botucatu Medical School, Botucatu, SP, Brazil.

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[Periocular poroma-a rare differential diagnosis to basal cell carcinoma].

Ophthalmologe 2021 Feb 26. Epub 2021 Feb 26.

Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Halle (Saale), Ernst-Grube-Str. 40, 06120, Halle (Saale), Deutschland.

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February 2021

Reactive eccrine syringofibroadenoma triggered by thermal damage: case report.

An Bras Dermatol 2021 Mar-Apr;96(2):255-256. Epub 2021 Jan 25.

Department of Basic Pathology, Biological Sciences Sector, Universidade Federal do Paraná, Curitiba, PR, Brazil.

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A rare combination of holocrine poroma with follicular germinative differentiation.

J Dermatol 2021 Apr 9;48(4):e192-e193. Epub 2021 Feb 9.

Department of Dermatology, Nara Medical University School of Medicine, Kashihara, Nara, Japan.

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Utility of YAP1 and NUT immunohistochemistry in the diagnosis of porocarcinoma.

J Cutan Pathol 2021 Mar 14;48(3):403-410. Epub 2020 Dec 14.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Background: Porocarcinoma is the malignant counterpart of poroma, a benign tumor derived from the eccrine or apocrine units. In contrast to poroma, porocarcinoma is rare and its diagnosis may be challenging. Recent work has identified YAP1-associated gene fusions in most poromas, and a subset of porocarcinomas. Read More

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Eccrine poroma of the eyelid.

Indian J Ophthalmol 2020 Nov;68(11):2522

Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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November 2020

Eccrine porocarcinoma: case report and review of the literature.

G Ital Dermatol Venereol 2020 Aug;155(4):500-504

Division of Plastic Surgery, Department of Surgical Sciences, University of Parma, Parma, Italy.

Eccrine porocarcinoma is a rare skin cancer that originates from the acrosyringium of eccrine sweat glands. From the clinical point of view the differential diagnosis with other skin cancers such as basal cell carcinoma and squamous cell carcinoma it is often impossible, only the histopathologic features can lead to the definitive diagnosis. Eccrine porocarcinoma can arise from a previous poroma or de novo, it may recur after surgical excision and cause lymph node and visceral metastasis. Read More

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Recurrent lesion on toe of young man.

JAAD Case Rep 2020 Oct 7;6(10):1003-1005. Epub 2020 Aug 7.

Louisiana State University Health Sciences Center, Department of Dermatology, New Orleans, Louisiana.

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October 2020

Visual Dermatology: Large Eccrine Poroma on the Sole.

J Cutan Med Surg 2020 Sep 21:1203475420960435. Epub 2020 Sep 21.

158013 Dermatology Centre, Dubai Health Authority, Dubai, United Arab Emirates.

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September 2020

A rare case of recurrent eccrine poroma underlying gluteal abscess.

Int J Surg Case Rep 2020 2;75:29-31. Epub 2020 Sep 2.

Department of Pharmacy Practice, Unaizah College of Pharmacy, Qassim University, Unaizah, Qassim, Saudi Arabia.

Introduction: Eccrine poroma is a benign adnexal neoplasm originating from epidermal sweat ducts mainly affecting the palmoplantar skin, buttock as a location of origin of poroma has rarely been reported, it is the first reported case of recurrent poroma in this site.

Presentation Of Case: We report an unusual case of eccrine poroma in the gluteal region of a 62 years old female associated with gluteal abscess, surgically excised with histologically clear margins, then recurred after one and half year with a given history of mild trauma.

Discussion: Given the uncommonness of these neoplasms, there stays a general lack of data on pathogenesis, atypical presentation, atypical sites, recurrence and risk of malignant transformation into porocarcinoma. Read More

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September 2020

A Growing Mass under the Nail: Subungual Eccrine Poroma.

Skin Appendage Disord 2020 Jul 25;6(4):254-257. Epub 2020 Jun 25.

Department of Pathology, Ankara Bilkent City Hospital, Ankara, Turkey.

Eccrine poroma is a benign adnexal tumour, which originates from the acrosyringium of eccrine sweat glands. Eccrine poroma is an uncommon neoplasm, the typical clinical presentation of which is a solitary soft sessile reddish papule protruding from a cup-shaped shallow depression. Many challenges remain in the diagnosis of eccrine poroma because it does not always present with classical features and may mimic any other cutaneous benign and malignant lesions. Read More

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Characteristic Clinical and Dermoscopic Features of Nonvolar Poroma.

J Cutan Med Surg 2021 Mar-Apr;25(2):142-149. Epub 2020 Sep 3.

34996 Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea.

Background: A poroma typically presents as a solitary, pink-to-red papule or nodule in acral volar areas. However, in nonvolar areas, this typical clinical feature (TCF) can be difficult to identify.

Objective: We aimed to compare clinical and dermoscopic characteristics between nonvolar poroma (NVP) and volar (ie, typical) poroma (VP). Read More

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September 2020

Morphologic Diversity of Merkel Cell Carcinoma.

Am J Dermatopathol 2020 Sep;42(9):629-640

Professor of Pathology, Department of Pathology, Harvard Medical School, Massachusetts General Hospital, Boston, MA.

Merkel cell carcinoma (MCC) is a rare and highly aggressive neuroendocrine carcinoma of unknown origin. We performed a retrospective histologic review of primary cutaneous MCCs diagnosed from 1997 to 2018 in several clinical institutions and literature review to determine the frequency of various unusual morphologic appearances of MCC. Of the 136 primary MCCs identified, intraepidermal carcinoma or epidermotropism was noted in 11/136 (8%) cases. Read More

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September 2020

A case of YAP1 and NUTM1 rearranged porocarcinoma with corresponding immunohistochemical expression: Review of recent advances in poroma and porocarcinoma pathogenesis with potential diagnostic utility.

J Cutan Pathol 2021 Jan 8;48(1):95-101. Epub 2020 Sep 8.

Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.

Porocarcinoma is a rare malignant adnexal tumor with predilection for the lower extremities and the head and neck region of older adults. This entity may arise de novo or in association with a benign poroma. Porocarcinoma's non-specific clinical appearance, immunohistochemical profile, and divergent differentiation may occasionally be diagnostically challenging. Read More

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January 2021

Eyelid Eccrine Poroma: A Case Report and Review of Literature.

Cureus 2020 Jun 29;12(6):e8906. Epub 2020 Jun 29.

Ophthalmology, 12 De Octubre Hospital, Complutense University, Madrid, ESP.

Poroma is a rare benign tumor of the epidermal sweat duct unit with predilection for the head and neck. Only six cases with eyelid location have been described in the literature (PubMed). A 34-year-old male presented with a single tumor on the left upper eyelid. Read More

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Multiple Plantar Poromas in a Stem Cell Transplant Patient.

Cureus 2020 Jun 22;12(6):e8773. Epub 2020 Jun 22.

Division of Dermatology and Dermatopathology, The Ohio State University Wexner Medical Center, Columbus, USA.

Poromatosis, or the formation of multiple eccrine poromas, is associated with chronic immunosuppression, lymphoproliferative neoplasms, and stem cell transplantation, though the etiology and clinical significance remain poorly understood. Eccrine poromas are asymptomatic, may appear years after treatment, and overlap morphologically with other diagnoses, particularly human papillomavirus-associated verrucae, to which immunosuppressed patients may be predisposed and commonly occur in similar sites. We report a 47-year-old female on chronic immunosuppression who developed multiple plantar eccrine poromas three years after achieving acute myeloid leukemia (AML) remission following treatment with chemotherapy, total body irradiation, and allogenic stem cell transplantation. Read More

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Dark Lesion with Irregular and Polymorphous Vascularization in Two Patients: A Quiz.

Acta Derm Venereol 2020 Jun 18;100(13):adv00195. Epub 2020 Jun 18.

Department of Dermatology, Pontevedra University Hospital, ES-36995 Pontevedra, Spain. E-mail:

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YAP1-MAML2-Rearranged Poroid Squamous Cell Carcinoma (Squamoid Porocarcinoma) Presenting as a Primary Parotid Gland Tumor.

Head Neck Pathol 2021 Mar 5;15(1):361-367. Epub 2020 Jun 5.

Department of Otorhinolaryngology, Head and Neck Surgery, Bundeswehrkrankenhaus, Berlin, Germany.

Porocarcinoma (synonym: malignant eccrine poroma) is a rare aggressive carcinoma type with terminal sweat gland duct differentiation. The squamous variant of porocarcinoma is even less frequent and might be indistinguishable from conventional squamous cell carcinoma (SCC). We herein describe the first case of a carcinoma presenting as a primary parotid gland malignancy in a 24-year-old male without any other primary tumor. Read More

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A string of nodular lesions along the leg.

J Dtsch Dermatol Ges 2020 Jul 25;18(7):774-776. Epub 2020 May 25.

Department of Dermatology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

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Eccrine porocarcinoma of the head and neck: Meta-analysis of 120 cases.

Head Neck 2020 09 21;42(9):2644-2659. Epub 2020 Apr 21.

Institute of Head and Neck Diseases, Evangelical Hospital Vienna, Vienna, Austria.

Background: The aim of the study is to analyze potential prognostic factors and to evaluate therapy strategies regarding clinical outcome in patients with eccrine porocarcinoma (EPC) of the head and neck.

Methods: One hundred and sixteen EPC cases from ninety studies and four authors' EPC cases were included in the meta-analysis.

Results: At an average follow up of 20. Read More

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September 2020