556 results match your criteria Poroma

Head and Neck Porocarcinoma: SEER Analysis of Epidemiology and Survival.

J Clin Med 2022 Apr 14;11(8). Epub 2022 Apr 14.

Department of Plastic, Reconstructive and Aesthetic Surgery, Geneva University Hospitals, University of Geneva, 1205 Geneva, Switzerland.

Porocarcinoma is a rare malignant adnexal tumor. Little is known about the location of the disease in the head and neck. Our aim is to offer the largest analysis of demographic, pathological, and treatment patterns of head and neck porocarcinoma in comparison with other locations of the neoplasm from an epidemiologically representative cohort. Read More

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Porocarcinoma of the left arm: A report of a rare skin cancer case and literature review.

Clin Case Rep 2022 Apr 15;10(4):e05721. Epub 2022 Apr 15.

Medical Oncology Unit Belcolle Hospital ASL Viterbo Viterbo Italy.

Porocarcinoma is a rare type of skin cancer that develops from the intraepidermal ductal part of eccrine sweat glands. It can arise de novo or from poroma ground with high potential for locoregional metastatic spread, morbidity, and mortality. It mostly occurs in elderly patients. Read More

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UV-induced local immunosuppression in the tumour microenvironment of eccrine porocarcinoma and poroma.

Sci Rep 2022 04 1;12(1):5529. Epub 2022 Apr 1.

Department of Pathology, University of Helsinki, P.O. Box 63, 00014, Helsinki, Finland.

Eccrine porocarcinoma (EPC) is a rare malignant adnexal tumour of the skin. Part of EPCs develop from their benign counterpart, poroma (EP), with chronic light exposure and immunosuppression hypothesized to play a role in the malignant transformation. However, the impact of chronic light exposure on the microenvironment of EPCs and EPs has not been investigated yet. Read More

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Breast metastases of eccrine porocarcinoma.

BMJ Case Rep 2022 Mar 7;15(3). Epub 2022 Mar 7.

Breast Unit, Champalimaud Clinical Center / Champalimaud Foundation, Lisbon, Portugal.

Eccrine porocarcinoma is a rare skin adnexal malignant neoplasm that may arise from a pre-existing benign eccrine poroma or without a predisposing factor. It is a highly invasive neoplasm and has a strong metastatic potential. The most frequently affected organs are the lymph nodes and rarely solid organs such as the liver, lungs and breast. Read More

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Dermal Duct Tumor: A Diagnostic Dilemma.

Dermatopathology (Basel) 2022 Jan 28;9(1):36-47. Epub 2022 Jan 28.

Center for Clinical Studies, Webster, TX 77598, USA.

Poromas or poroid tumors are a group of rare, benign cutaneous neoplasms derived from the terminal eccrine or apocrine sweat gland duct. There are four poroma variants with overlapping features: dermal duct tumor (DDT), eccrine poroma, hidroacanthoma simplex, and poroid hidradenoma, of which DDT is the least common. Clinically, the variants have a nonspecific appearance and present as solitary dome-shaped papules, plaques, or nodules. Read More

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January 2022

Fusion-positive skin/adnexal carcinomas.

Abbas Agaimy

Genes Chromosomes Cancer 2022 05 7;61(5):274-284. Epub 2022 Mar 7.

Pathologisches Institut, Universitätsklinikum Erlangen, Erlangen, Germany.

Gene fusions have been increasingly identified as central events driving oncogenesis in a variety of benign and malignant neoplasms of different histogenesis originating in diverse organs. While some fusion-driven neoplasms may occur at any body site, certain genotypes and their associated phenotypic entities cluster to specific body site/organ, albeit with variable frequencies among anatomic locations. In the last two decades, several skin adnexal entities driven by specific fusions have been described; some of them represent new entities (eg, secretory carcinoma harboring NTRK fusions), while others are old established entities with newly discovered underlying gene fusions (eg, poroid neoplasms harboring NUTM1, YAP1, and WWTR1 fusions). Read More

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Recent Advances on Immunohistochemistry and Molecular Biology for the Diagnosis of Adnexal Sweat Gland Tumors.

Cancers (Basel) 2022 Jan 18;14(3). Epub 2022 Jan 18.

French Network of Rare Skin Cancers, CARADERM, France.

Cutaneous sweat gland tumors are a subset of adnexal neoplasms that derive or differentiate into the sweat apparatus. Their great diversity, rarity, and complex terminology make their pathological diagnosis challenging. Recent findings have revealed a wide spectrum of oncogenic drivers, several of which are of diagnostic interest for pathologists. Read More

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January 2022

Combined Poroma and Verruca Plantaris.

Am J Dermatopathol 2022 May;44(5):e51-e53

Departments of Dermatology and Pathology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA.

Abstract: A 76-year-old female patient presented with a peculiar new exophytic-appearing, flesh-colored skin lesion on her left hallux. Owing to its atypical appearance, the neoplasm was biopsied. Histologic sections demonstrated numerous thickened, anastomosing cord-like structures composed of bland appearing adnexal keratinocytes attached to the epidermis and extending into the superficial dermis. Read More

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Unusual Presentations of Eccrine Porocarcinomas.

Skin Appendage Disord 2022 Jan 8;8(1):61-64. Epub 2021 Sep 8.

Dermatology & Surgery Clinic, Singapore, Singapore.

Eccrine porocarcinomas (EPCs) are rare tumours, albeit the most common malignant adnexal tumours of the skin. They can present with very heterogeneous clinical and dermoscopic features, rendering diagnosis limited to histopathological examination alone. We share 2 cases of EPCs, one of which arose in a patient with a prior diagnosis of cutaneous squamous cell carcinoma (SCC) and another whose EPC was likely a malignant transformation of an existing poroma. Read More

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January 2022

Metastatic Porocarcinoma Effectively Managed by Pembrolizumab.

Cureus 2021 Nov 29;13(11):e20004. Epub 2021 Nov 29.

Hematology and Oncology, Cape Fear Valley Medical Center, Fayetteville, USA.

Eccrine porocarcinoma (EPC) is a rare malignancy of the sweat glands. Currently, there is no standard algorithm for its presentations, diagnosis, and management. However, immunotherapy is an emerging option that may be crucial to the treatment of EPC. Read More

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November 2021

Expression and Significance of AQP3 in Cutaneous Lesions.

Anal Cell Pathol (Amst) 2021 26;2021:7866471. Epub 2021 Oct 26.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Pathology, Peking University Cancer Hospital & Institute, Beijing, China.

Aquaporin 3 (AQP3) is the membrane channel of water and involved in fluid homeostasis. The aim of this study was to reveal the expression and significance of AQP3 in cutaneous lesions. We analyzed AQP3 mRNA levels using RT-PCR in 311 cutaneous lesions and confirmed AQP3 expression in these lesions by immunohistochemistry. Read More

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Pigmented poroma on the scalp clinically mimicking basal cell carcinoma.

An Bras Dermatol 2021 Nov-Dec;96(6):793-795. Epub 2021 Sep 24.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan.

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January 2022

A systematic review of periungual eccrine neoplasms.

Int J Dermatol 2021 Sep 8. Epub 2021 Sep 8.

Department of Dermatology, MetroHealth System, Cleveland, OH, USA.

Eccrine tumors are a rare cutaneous adnexal neoplasm originating from the sweat glands. The periungual region represents an uncommon localization for these neoplasms. We analyzed all published demographic, clinical, and treatment data on periungual eccrine tumors. Read More

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September 2021

Eccrine poromatosis and polychemotherapy.

Int J Dermatol 2022 Apr 25;61(4):e132-e134. Epub 2021 Aug 25.

Medical Department, National Skin Centre, Singapore.

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Merkel cell polyomavirus is a passenger virus in both poroma and porocarcinoma.

J Cutan Pathol 2022 Jan 11;49(1):49-54. Epub 2021 Aug 11.

Department of Plastic Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Background: Merkel cell polyomavirus (MCPyV) has been studied in several malignant and nonmalignant tissues. However, only in Merkel cell carcinoma (MCC) has the connection to tumorigenesis been established. Previously, eccrine porocarcinoma samples were shown to express MCPyV in the majority of samples. Read More

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January 2022

Rare case of large eccrine poroma of the eyelid.

Med J Armed Forces India 2021 Jul 6;77(3):371-373. Epub 2020 Oct 6.

Consultant (Anterior Segment), Shri Ganesh Vinayak Eye Hospital, Raipur, Chhattisgarh, India.

Eccrine poroma is a rare tumor arising from sweat glands with common location being soles and palms. We are reporting a case of 70-year male patient with large lower lid mass lesion. Owing to its location and history of growth, malignancy was suspected. Read More

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Eccrine poroma of the eyelid.

Orbit 2021 Jul 14. Epub 2021 Jul 14.

Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.

Clinical and histopathologic case of an eyelid eccrine poroma, a benign adnexal neoplasm rarely found on the periorbital skin. Read More

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Dermoscopic and confocal microscopic presentation of apocrine poroma.

JAAD Case Rep 2021 Aug 11;14:21-23. Epub 2021 Jun 11.

Dermatology Center, Hospital CUF Descobertas, Lisboa, Portugal.

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Poroid hidradenoma of the scalp.

Arch Craniofac Surg 2021 Jun 25;22(3):154-156. Epub 2021 Jun 25.

Department of Pathology, Bundang Jesaeng Hospital, Seongnam, Korea.

Poroid hidradenoma has both features of hidradenoma and poroma. The histological hidradenoma framework consisting of solid and cystic components, and the presence of poroid and cuticular cells resembling a poroid neoplasm. Despite transforming into malignant neoplasm only in < 1% of cases, its histological characteristics may resemble those of malignant neoplasms. Read More

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Pigmented eccrine poroma on the palm mimicking seborrheic keratosis: Dermoscopic findings and a review of reported cases.

Australas J Dermatol 2021 Aug 2;62(3):e477-e479. Epub 2021 Jul 2.

Department of Dermatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

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Molecular pathology of skin adnexal tumours.

Histopathology 2022 Jan;80(1):166-183

Department of Pathology, University of Michigan, Ann Arbor, MI, USA.

Aims: Tumours of the cutaneous adnexa arise from, or differentiate towards, structures in normal skin such as hair follicles, sweat ducts/glands, sebaceous glands or a combination of these elements. This class of neoplasms includes benign tumours and highly aggressive carcinomas. Adnexal tumours often present as solitary sporadic lesions, but can herald the presence of an inherited tumour syndrome such as Muir-Torre syndrome, Cowden syndrome or CYLD cutaneous syndrome. Read More

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January 2022

Pigmented nodule on the dorsum of the foot.

JAAD Case Rep 2021 Jul 12;13:49-51. Epub 2021 May 12.

Division of Dermatology, National University Hospital, Singapore.

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Secondary Amyloid Deposition in Pigmented Poroma.

Actas Dermosifiliogr (Engl Ed) 2021 Jun 17. Epub 2021 Jun 17.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan. Electronic address:

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A unique collision mimicking nodular melanoma.

JAAD Case Rep 2021 Jul 29;13:11-13. Epub 2021 Apr 29.

Department of Dermatology, University of Genoa, San Martino Polyclinic Hospital Istituto di Ricovero e Cura a Carattere Scientifico, Genoa, Italy.

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Comparative Immunohistochemical Study of Hidroacanthoma Simplex and Clonal Seborrheic Keratosis With GATA3 and p63.

Am J Dermatopathol 2022 01;44(1):17-20

Department of Dermatology, Chang Gung Memorial Hospital, Linkou and Taipei, Taiwan.

Abstract: Histopathologically both hidroacanthoma simplex (HS) and clonal seborrheic keratosis (CSK) are characterized by intraepidermal nests of tumor cells. Although they show subtle microscopic differences, they can be difficult to accurately differentiate. Previous immunohistochemical studies have been inconclusive. Read More

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January 2022

Eccrine poroma presented as spindle-shaped plaque: A case report.

Medicine (Baltimore) 2021 May;100(20):e25971

Department of Dermatology, the Second Affiliated Hospital of Xi'an Jiaotong University, School of Medicine, Xi'an, China.

Rationale: Eccrine poroma, a benign cutaneous neoplasm originating from the intraepidermal portion of the eccrine sweat duct, is relatively common in clinical practice. Nevertheless, the 1 presenting as spindle-shaped plaque is extremely rare and easily misdiagnosed as seborrheic keratosis or other dermatoses. Thus, the current study demonstrates a case of eccrine poroma with unique clinical manifestation. Read More

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Secondary Amyloid Deposition in Pigmented Poroma.

Actas Dermosifiliogr (Engl Ed) 2021 May 5. Epub 2021 May 5.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan. Electronic address:

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Eccrine Poroma Arising within Nevus Sebaceous.

Ann Dermatol 2020 Dec 11;32(6):516-518. Epub 2020 Nov 11.

Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, Korea.

Secondary neoplasms in nevus sebaceous can develop during adolescence and adulthood. Trichoblastoma and syringocystadenoma papilliferum are the most common benign neoplasms, but poroma is rarely reported. A 28-year-old female presented with an asymptomatic mass on the scalp. Read More

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December 2020

A Case of Eccrine Poromatosis in a Patient with a History of Chemotherapy Due to Stomach Cancer.

Ann Dermatol 2020 Oct 29;32(5):422-425. Epub 2020 Sep 29.

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

An eccrine poroma (EP) is a benign adnexal tumor that typically presents as a single lesion. Eccrine poromatosis defined as multiple EPs is an uncommon presentation. A 54-year-old male had undergone operation for stomach cancer 10 years prior and insisted that he had also taken adjuvant chemotherapy. Read More

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October 2020

Eccrine Porocarcinoma: A Multicenter Retrospective Study with Review of the Literatures Reported in Korea.

Ann Dermatol 2020 Jun 24;32(3):223-229. Epub 2020 Apr 24.

Department of Dermatology, College of Medicine, Korea University, Seoul, Korea.

Background: Eccrine porocarcinoma (EPC) is a rare malignant cutaneous adnexal tumor. Other than several scattered case reports, no comprehensive review on EPC has been conducted in Korea.

Objective: To clinicopathologically review all EPC cases from our institutions as well as those reported in Korea. Read More

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