458 results match your criteria Poroma
An Bras Dermatol 2018 Nov/Dec;93(6):896-898
Service of Dermatology, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP), Brazil.
Poroid neoplasms are benign epithelial proliferations with eccrine sweat gland differentiation. They are a challenging diagnosis because of the clinical heterogeneity, being able to mimic several malignant neoplasms. They are classified into classic poroma, hidroacanthoma simplex, dermal duct tumor and poroid hidradenoma. Read More
J Am Acad Dermatol 2018 Oct 1. Epub 2018 Oct 1.
Case Western Reserve University School of Medicine Department of Dermatology, Cleveland, Ohio, U.S.A; University Hospitals Cleveland Medical Center, Cleveland, Ohio, U.S.A.
Indian Dermatol Online J 2018 Jul-Aug;9(4):259-261
Department of Dermatology, Rutgers Robert Wood Johnson Medical School, Somerset, New Jersey, USA.
Eccrine poroma is a benign adnexal tumor that originates from the uppermost portion of the intraepidermal eccrine duct. It usually presents as a solitary tumor. Histopathology shows a monomorphic proliferation of cuboidal cells, which radially extend from the basal layer to the dermis. Read More
J Hand Surg Am 2018 Jul 20. Epub 2018 Jul 20.
Department of Orthopedic Surgery, Hand and Upper Extremity Service, Harvard Medical School, Boston, MA.
Poromas are benign adnexal neoplasms originating from the intraepidermal portion of sweat gland ducts. With the possibility of malignant transformation, accurate clinical diagnosis and treatment are crucial. Numerous reports of hand poroma lesions have been reported. Read More
Australas J Dermatol 2018 Jun 26. Epub 2018 Jun 26.
Division of Dermatology and Dermatopathology, Nippon Medical School Musashi Kosugi Hospital, Kawasaki, Japan.
We report on three patients exhibiting tumours with exophytic pedunculated structures with eroded surfaces. All cases showed the basic histopathological features of poroma accompanied by large, invaginated ductal structures lined by multiple layers of columnar or cuboidal cells. The columnar cells of invaginated ductal/cystic structures focally exhibited subtle features reminiscent of decapitation secretion along with dense infiltration of plasma cells in the surrounding stroma, mimicking syringocystadenoma papilliferum. Read More
Medicine (Baltimore) 2018 Jun;97(25):e11154
Department of Radiology, Konkuk University School of Medicine, Seoul.
Rationale: Poroid hidradenoma (PH) is a rare variant of benign sweat gland neoplasm without connection to the epidermis. This tumor presents clinically as a solitary lesion with a cystic component located in the subcutaneous layer abutting the skin. On ultrasound, it appears as a circumscribed complex cystic and solid mass abutting the dermis. Read More
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 Jul;31(13):1041-1042
Eccrine poroma is a benign neoplasm of the terminal duct. It is commonly located in distal extremities but rarely present in head and neck. This report mainly describes a case of external nose eccrine poroma. Read More
Ann Dermatol 2018 Apr 21;30(2):222-225. Epub 2018 Feb 21.
Department of Dermatology, SMG-SNU Boramae Medical Center, Seoul, Korea.
Eccrine poroma is a benign solitary tumor with acrosyringeal differentiation that usually occurs on the sole or either side of the foot. Rapid growth of eccrine poroma during pregnancy has rarely been reported. We demonstrate a unique case of a 37-year-old pregnant woman who suffered from enlarged eccrine poroma on her left palm, which was tiny for 10 years but suddenly grew to a size of bean-sized reddish brown colored, pedunculated mass during pregnancy. Read More
Histopathology 2018 Jun 25;72(7):1199-1208. Epub 2018 Mar 25.
Department of Human Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Aims: A number of homeobox transcriptional factors are utilised as organ-specific markers in the histopathological diagnosis of neoplasms. We have screened a homeobox gene that is expressed specifically in normal sweat gland cells and is useful for the histopathological diagnosis of sweat gland neoplasms.
Methods And Results: By screening an open database resource of The Human Protein Atlas, 37 genes among the 235 homeobox transcriptional factors were found to be expressed specifically in the skin. Read More
J Cytol 2018 Jan-Mar;35(1):60-62
Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
The primary and metastatic tumors of the skin can be effectively diagnosed by fine needle aspiration cytology (FNAC); however, the cytomorphological features of skin adnexal tumors are rarely described in the literature. We hereby describe the cytological features of two histologically confirmed cases of benign skin adnexal tumors. Case 1 is of a 46-year-old female who presented with an elevated firm nodule over the scalp. Read More
Am J Dermatopathol 2018 Jul;40(7):e104-e106
Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
Poromas are benign cutaneous adnexal neoplasms with differentiation toward excretory ducts of eccrine and apocrine glands. They are mainly composed of solid aggregates of small, monomorphous, round, and basophilic poroid cells, with a lower proportion of larger, squamous, eosinophilic cuticular cells, which are lining ductal structures with an eosinophilic luminal cuticle. In most cases of poromas, cuticular cells represent a small proportion of the neoplastic aggregates. Read More
Am J Dermatopathol 2017 Dec 28. Epub 2017 Dec 28.
Departments of Pathology, and.
Pathology 2018 Apr 18;50(3):327-332. Epub 2017 Dec 18.
Institute of Pathology, University of Heidelberg, Heidelberg, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany. Electronic address:
The genetic landscape of rare benign tumours and their malignant counterparts is still largely unexplored. While recent work showed that mutant HRAS is present in subsets of poromas and porocarcinomas, a more comprehensive genetic view on these rare adnexal neoplasms is lacking. Using high-coverage next generation sequencing, we investigated the mutational profile of 50 cancer-related genes in 12 cases (six poromas and six porocarcinomas). Read More
J Am Podiatr Med Assoc 2017 Nov;107(6):551-555
Eccrine poroma is a rare benign adnexal neoplasm originating from a portion of the intraepidermal eccrine sweat gland duct and the acrosyringium. Typically, the lesions are asymptomatic, slow-growing nodules, which may be found in any sweat gland-bearing area. Multiple red lacunae, glomerular vessels, hairpin vessels, flower- and leaf-like vascular patterns, a polymorphic vascular pattern, globule/lacunae-like structures, a frog egg-like appearance, and comedo-like openings have been defined as characteristic dermoscopic patterns of the disease. Read More
Int J Surg Case Rep 2018 8;42:116-120. Epub 2017 Dec 8.
Department of Pathology, Sultanah Nur Zahirah Hospital, Jalan Sultan Mahmud, 20400, Kuala Terengganu, Terengganu, Malaysia.
Introduction: Cutaneous appendageal tumor can differentiate towards or arise from either pilosebaceous apparatus or the eccrine sweat glands. Appendageal tumors are relatively rare, their clinical appearance is non-specific, and the vast majority are not diagnosed until after excision. Eccrine porocarcinoma (EP), also known as malignant eccrine poroma is a rare adnexal tumor arising from the intraepithelial ductal parts of the sweat gland. Read More
J Eur Acad Dermatol Venereol 2017 Dec 1. Epub 2017 Dec 1.
Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Background: Poromas are benign cutaneous sweat gland tumours that are challenging to identify. The dermoscopic features of poromas are not well characterized.
Objective: To determine the clinical-dermoscopic features of poromas. Read More
J Dermatol 2018 Apr 15;45(4):e94-e95. Epub 2017 Nov 15.
Department of Dermatology, Nippon Medical School, Tokyo, Japan.
Am J Dermatopathol 2018 Jun;40(6):401-408
Department of Pathology, Montefiore Medical Center, Bronx, NY.
There are 36 cases of complex poroid tumors with folliculosebaceous and apocrine differentiation reported in the literature. The authors evaluated 111 poroid tumors including 63 typical eccrine poromas and 48 poroid tumors with folliculosebaceous elements. Folliculosebaceous poroid tumors (FSPT) had basaloid and squamous cells (100%), ducts with steatocystoma-like cuticles and holocrine secretions (89. Read More
Dermatol Pract Concept 2017 Jul 31;7(3):35-37. Epub 2017 Jul 31.
Department of Dermatology, Mogi das Cruzes University, Mogi das Cruzes, Brazil.
Reticulated acanthoma with sebaceous differentiation (RASD) is a rare, benign cutaneous tumor with peculiar histopathologic characteristics . RASD had been described under various synonyms such as superficial epithelioma with sebaceous differentiation, sebocrine adenoma, poroma with sebaceous differentiation, and seborrheic keratosis with sebaceous differentiation . Clinical differential diagnosis of RASD includes cutaneous superficial epithelial neoplasia such as Bowen's disease, superficial basal cell carcinoma (BCC) and intraepidermal eccrine poroma . Read More
Case Rep Surg 2017 19;2017:9865672. Epub 2017 Sep 19.
Department of Anatomy, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Poroma is a rare benign neoplasm that derives from eccrine sweat glands epithelium. Its histological subtypes, with respect to its position within skin layers, are eccrine poroma, hidroacanthoma simplex, poroid hidradenoma, and dermal duct tumor. Poromas commonly exhibit benign clinical behavior as they are usually small and asymptomatic and do not exhibit malignant behavior. Read More
Ann R Coll Surg Engl 2017 Nov 15;99(8):e230-e232. Epub 2017 Sep 15.
Children's Surgical Centre , Phnom Penh , Cambodia.
A 53-year-old Cambodian woman presented with nodular masses on the right arm suggestive of a sarcoma-type malignancy. The masses were excised and identified as multiple benign eccrine poromas. The patient re-presented after two years with large relapsed tumours and axillary lymph node involvement. Read More
Dermatol Surg 2018 05;44(5):740-741
Department of Dermatology, Division of Dermatologic Surgery, Mayo Clinic, Rochester, Minnesota.
An Bras Dermatol 2017 Jul-Aug;92(4):550-552
Faculty of Medicine, Pontificia Universidad Católica de Chile - Santiago, Chile.
Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Read More
Arch Craniofac Surg 2017 Mar 25;18(1):44-45. Epub 2017 Mar 25.
Department of Plastic and Reconstructive Surgery, Dongguk University College of Medicine, Gyeongju, Korea.
Eccrine poroma is a common benign cutaneous tumor that originates in an intraepidermal eccrine duct. This tumor exhibits acral distribution (sole, palm), and is rarely encountered in the head and neck area. In fact eccrine poroma in the postauricular area has only been rarely reported. Read More
Dermatol Surg 2018 May;44(5):738-740
Department of Dermatology, University of Texas Medical Branch, Galveston, Texas.
Indian Pediatr 2017 08;54(8):698
Departments of Dermatology and #Pathology, Farhat Hached Hospital, Tunisia.
Actas Dermosifiliogr 2018 Jan - Feb;109(1):67-68. Epub 2017 Aug 23.
Servicio de Dermatología, Complejo Hospitalario Universitario de Granada, Granada, España.
Int J Womens Dermatol 2017 Sep 14;3(3):157-160. Epub 2017 Jul 14.
Department of Dermatology, University of Connecticut School of Medicine, Farmington, CT.
Porocarcinoma is a rare malignant neoplasm of the acrosyringium with metastatic potential that most commonly presents on the acral skin in older adults (mean age = 72 years). We present the case of a 43-year-old woman who developed a rapidly growing de novo porocarcinoma on the scalp with an unusual oncocytic appearance. The tumor consisted of benign eccrine poroma that arose from the epidermis and broad pushing borders with minimal cytological atypia but ample eosinophilic cytoplasm with numerous mitotic figures. Read More
An Bras Dermatol 2017 Mar-Apr;92(2):253-255
Department of Dermatology. Hospital do Servidor Público Estadual de São Paulo - São Paulo (SP), Brazil.
Hidroacanthoma simplex is a rare intraepidermal neoplasia that arises from the acrosyringial portion of the eccrine duct. Malignant transformation of hidroacanthoma simplex is reported in the literature and the treatment is performed with wide excision or Mohs micrographic surgery. We report the first case successfully treated with cryosurgery with a long-term follow up. Read More
Eur J Dermatol 2017 08;27(4):405-406
Department of Dermatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8510 Japan.
Am J Dermatopathol 2017 Jul;39(7):534-537
Departments of *Pathology, and †Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL; ‡Robert H. Lurie Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL; §Division of Dermatology, Department of Medicine, NorthShore University HealthSystem Vernon Hills, IL; and ¶Dermatology and Aesthetics of Wicker Park, Chicago, IL.
A 75-year-old man with human immunodeficiency virus infection and numerous biopsy-proven warts for 10 years, refractory to cryosurgery, cimetidine, and topical imiquimod, presented with numerous pink to hypopigmented verrucous papules and plaques involving the face, trunk, buttocks, and groin. Laboratory evaluation revealed a CD4 T-cell count of 62 cells per microliter and human immunodeficiency virus viral load of <117 copies per milliliter. Biopsy of a plaque groin lesion was performed. Read More
Appl Immunohistochem Mol Morphol 2017 02;25(2):e14-e17
*Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain †Department of Pathology, Southern California Kaiser Permanente, Los Angeles Medical Center (LAMC), Los Angeles, CA.
We present the case of a 43-year-old white man with a complex lesion at the base of the penis that combines features of both a poroma and a condyloma with human papillomavirus (HPV) infection, atypias, and focal ductal differentiation. It was a papillomatous lesion with epidermal hyperplasia, which mainly contained focally pigmented monotonous basaloid cells. Ductal lumina with cuticular cells were easily identified. Read More
J Am Acad Dermatol 2017 Feb;76(2S1):S46-S48
Department of Dermatology, University Hospital "Dr. José Eleuterio González," Universidad Autónoma de Nuevo León, Monterrey, Mexico. Electronic address:
Rom J Morphol Embryol 2017 ;58(4):1611-1616
Pathology Unit, Department of Medical and Surgical Sciences, University of Cantabria and IDIVAL, Santander, Spain;
Adnexal carcinomas of the vulva are rare tumors. A case of an 83-year-old woman with a 3.5 cm vulvar lobulated mass that grew over an 18-month period is reported. Read More
Indian Dermatol Online J 2016 Nov-Dec;7(6):546-547
Private Consultant, Kasturmahal Polyclinic, Mumbai, Maharashtra, India.
Int J Surg Case Rep 2017 18;30:13-16. Epub 2016 Nov 18.
Bioscience Center. Goran Street, Sulaimani, Kurdistan Region, Iraq.
Introduction: Eccrine porocarcinoma is a very rare type of skin cancer. It is an aggressive dermatological malignancy. We presented a 62-year-old male with long history of a mass in left forearm complicated by distant metastasis and death. Read More
Eur J Dermatol 2016 Oct;26(5):519-520
Department of Dermatovenereology of Hospital Garcia de Horta, Almada, Portugal.
J Eur Acad Dermatol Venereol 2016 Nov 9;30(11):e167-e169. Epub 2015 Nov 9.
Department of Dermatology, Venereology and Allergology, Medical Center of the University of Heidelberg (UKH), Ruprecht-Karls-University, Heidelberg, Germany.
J Eur Acad Dermatol Venereol 2016 Oct 31;30(10):e61-e63. Epub 2015 Aug 31.
Dermatology Unit, Second University of Naples, Naples, Italy.
Case Rep Oncol 2016 May-Aug;9(2):454-456. Epub 2016 Aug 17.
Medical Oncology, Calvary Mater Newcastle, Waratah, N.S.W., Australia.
The successful treatment of the rare malignancy eccrine porocarcinoma (EP) is extremely challenging, often not rewarding and when associated with metastatic disease, therapy results are disappointing. We present a unique case of treatment response of metastatic EP, with a significant disease-free interval. The patient has remained in clinical and radiological remission for 36 months since diagnosis of metastatic disease. Read More
Dermatol Pract Concept 2016 Jul 31;6(3):59-62. Epub 2016 Jul 31.
Dermatology and Skin Cancer Unit, Arcispedale S. Maria Nuova, IRCCS, Reggio Emilia, Italy.
Eccrine poroma is a rare benign adnexal tumor of epithelial cells originating from the terminal ductal portion of the sweat glands that is typically located on palms and soles, although other cutaneous sites can be affected . It is usually nonpigmented even if there is a pigmented variant that corresponds to 17% of cases and it is usually underdiagnosed, since it is mistakenly confused with other pigmented tumors [2,3]. Dermoscopy and reflectance confocal microscopy (RCM) may assist in the correct diagnosis of this tumor. Read More
Indian J Dermatol 2016 Jul-Aug;61(4):430-2
Department of Dermatology, Venereology and Leprosy, IPGMER and SSKM Hospital, Kolkata, West Bengal, India.
Malignant eccrine poroma is a rare malignancy of the eccrine sweat glands, occurring most frequently on the lower extremities. It affects both sexes equally usually in the 6(th) to 7(th) decade of life. Metastasis to regional lymph nodes may occur in 20% that may be fatal in 60% cases. Read More
Skinmed 2016;14(3):175-80. Epub 2016 Jun 1.
Department of Pathology, Yong Loo Lin School of Medicine, National University Health System and National University of Singapore.
Eccrine tumors are adnexal tumors with a varied clinical presentation and wide histological spectrum. This study aims to consolidate data on the clinical characteristics of eccrine tumors to help improve clinical acumen and management of such tumors. Histopathological records from January 2008 to December 2012 were retrieved. Read More
Acta Dermatovenerol Croat 2016 Jun;24(2):158-60
Mattia Fadel, MD, Dermatology Department, University of Trieste, Ospedale Maggiore, Piazza dell'Ospitale 1, 34135 Trieste, Italy;
Dear Editor, Apocrine hidradenoma is a rare benign adnexal tumor related to the more common poroma, as they both originate from sweat glands. Hidradenoma usually has an eccrine differentiation, but an apocrine differentiation is possible. Due to its rarity and non-specific clinical appearance it is difficult to differentiate it from other malignant cutaneous lesions. Read More
J Dermatol 2017 Mar 30;44(3):345-346. Epub 2016 May 30.
Department of Dermatology, Fukushima Medical University, Fukushima, Japan.
JAAD Case Rep 2016 Mar 20;2(2):171-3. Epub 2016 Apr 20.
Division of Dermatology, University Medicine Cluster, National University Health System, Republic of Singapore.
Case Rep Dermatol 2016 Jan-Apr;8(1):80-4. Epub 2016 Apr 20.
Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Nevus sebaceous is a congenital, benign hamartomatous lesion, characterized by a yellowish to skin-colored, hairless, verrucous plaque on the head and neck region. In later life, a secondary tumor, either benign or malignant, can develop within nevus sebaceous. Eccrine poroma developing on nevus sebaceous is extremely rare. Read More
J Am Acad Dermatol 2016 Jun;74(6):e113-5
Melanoma Unit, Dermatology Department, Hospital Clínic & IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Barcelona, Spain; Centro Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III (ISCIII), Barcelona, Spain; Universitat de Barcelona, Barcelona, Spain. Electronic address:
Skin Appendage Disord 2015 Sep 12;1(2):95-8. Epub 2015 Aug 12.
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Ala., USA.
Eccrine poromas arise from the intraepidermal region of the eccrine sweat duct and most often occur as a benign solitary tumor. There are few reports of the occurrence of multiple lesions, defined as poromatosis, which may present in patients who have undergone radiotherapy and/or polychemotherapy. We report the case of a 43-year-old male with a history of mantle cell lymphoma who had undergone 6 cycles of polychemotherapy. Read More