1,279 results match your criteria Porokeratosis


A rare case of disseminated superficial porokeratosis-Case report.

J Family Med Prim Care 2022 Mar 10;11(3):1195-1197. Epub 2022 Mar 10.

Department of Dermatology, Venereology and Leprosy, SRM Medical College Hospital and Research Centre, Potheri, Chennai, Tamil Nadu, India.

Porokeratosis is a keratinization disorder characterized by hyperkeratotic sharply demarcated plaques with central atrophy and histopathologically, by cornoid lamella. A 30-year-old male presented with multiple pruritic dark raised skin lesions over the trunk, face, and upper limbs for past 3 years. Cutaneous examination revealed hyperkeratotic annular plaques with raised margins over face, trunk, and arms. Read More

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Porokeratotic adnexal ostial nevus: A paradigm of cutaneous mosaicism.

Clin Case Rep 2022 Apr 12;10(4):e05728. Epub 2022 Apr 12.

Department of Dermatology South Infirmary Victoria University Hospital Cork Ireland.

Porokeratotic adnexal ostial nevus (PAON) is a term encompassing porokeratotic eccrine ostial and dermal duct naevus (PEODDN) and porokeratotic eccrine and hair follicle naevus (PEHFN). We present the case of a 7-year-old girl who presented with hyperkeratotic verrucous papules in a blaschkolinear distribution on the sole of her left foot. Read More

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Eruptive superficial porokeratosis in a patient with nephrotic syndrome.

An Bras Dermatol 2022 Mar 20. Epub 2022 Mar 20.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan.

A 34-year-old female was referred to our department, complaining of multiple asymptomatic lesions that appeared two weeks previously. The patient had active nephritis with nephrotic syndrome and was treated with immunosuppressive therapies. Physical examination revealed multiple well-circumscribed rounds of flat brownish plaques with slightly elevated borders, some of which were covered by scales. Read More

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Coexistence of multiple porokeratoma and porokeratosis of Mibelli.

Ann Dermatol Venereol 2022 Mar 16. Epub 2022 Mar 16.

Pathology Clinic, Bakirköy Dr. Sadi Konuk Research and Training Hospital, 34450 Istanbul, Turkey.

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Follicular Porokeratosis of the Scalp: First Description of Clinical and Trichoscopic Features.

Int J Trichology 2022 Jan-Feb;14(1):25-27. Epub 2022 Feb 1.

Department of Dermatology, Príncipe de Asturias University Hopsital y El Bierzo Hospital, Madrid, Spain.

Porokeratosis (PK) is an epidermal disorder of keratinization, caused by a clone expansion of a mutated keratinocyte that generates a thin parakeratotic column: the cornoid lamella (CL). Depending on the clinical presentation, we differentiate up to 6 different types of PK. Most frequent locations for the lesions are limbs and trunk, while scalp is rarely affected. Read More

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February 2022

Porokeratosis: a differential diagnosis to consider in benign lichenoid keratosis.

Int J Clin Exp Pathol 2022 15;15(2):56-62. Epub 2022 Feb 15.

Dermatology Division, Department of Anatomical Pathology, Pathlab 829 Cameron Road, Tauranga 3112, New Zealand.

Porokeratosis is a disorder of keratinization with many clinical variants. The histological hallmark feature of porokeratosis is a cornoid lamella. Other accompanying features include lichenoid inflammation, atrophy towards the centre of the lesion, dermal cytoid bodies, and adjacent lichenoid changes. Read More

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February 2022

Disseminated superficial porokeratosis: Impact on quality of life.

J Am Acad Dermatol 2022 Feb 23. Epub 2022 Feb 23.

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.

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February 2022

Visual Dermatology: Generalized Linear Porokeratosis.

Authors:
Yang Lu Lin Feng

J Cutan Med Surg 2022 Feb 8:12034754221077925. Epub 2022 Feb 8.

117933 Department of Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China.

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February 2022

Verrucous Porokeratosis treated with 2940 nm Erbium:YAG laser.

Dermatol Ther 2022 Apr 14;35(4):e15342. Epub 2022 Feb 14.

Cerrahpaşa Medical Faculty, Dermatology Department, İstanbul University-Cerrahpaşa, İstanbul, Turkey.

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Porokeratoma: A distinct variant of porokeratosis.

J Cutan Pathol 2022 Jan 24. Epub 2022 Jan 24.

Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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January 2022

Porokeratosis Ptychotropica: Dermoscopy, Reflectance Confocal Microscopy, and Histopathological Correlation.

Indian J Dermatol 2021 Sep-Oct;66(5):540-542

Dermatology Clinic, University of Catania, Catania, Italy.

Porokeratosis ptychotropica (PP) is a rare variant of porokeratosis characterized by pruritic, symmetrical, red-brown verrucous papules, and plaques most commonly localized within the gluteal fold. Herein, we report the clinical, dermoscopy, and reflectance confocal microscopy (RCM) aspects of a case of PP in a 63-year-old Caucasian woman along with histopathological correlation. Both dermoscopy and RCM were able to recognize the , the histopathological clue shared by all clinical variants of porokeratosis. Read More

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January 2022

Porokeratoma treated with topical 5% 5-fluorouracil cream.

Int J Womens Dermatol 2021 Dec 25;7(5Part B):830-831. Epub 2021 Jul 25.

Laser and Dermatologic Surgery Center, St. Louis, Missouri.

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December 2021

Annular lichenoid diseases.

Clin Dermatol 2021 Dec 31. Epub 2021 Dec 31.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida, USA.

Annular lichenoid diseases encompass a diverse range of pathologies that present as circular, raised, or flat lesions that may vary in size and number. Examples include annular lichenoid dermatitis of youth, annular lichen planus, erythema dyschromicum perstans, erythema multiforme, fixed drug eruption, lichen sclerosus, neonatal lupus, porokeratosis, subacute cutaneous lupus erythematosus, and lichenoid syphilis. Clinical morphology and histopathology can differentiate these entities. Read More

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December 2021

Porokeratotic eccrine ostial and dermal duct nevus associated with an 11 megabase 3p deletion.

Pediatr Dermatol 2022 Jan 20;39(1):107-111. Epub 2021 Dec 20.

Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.

Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare eccrine hamartoma; the etiology is incompletely understood. A patient presented with congenital, widespread PEODDN. Clinical assessment, histopathologic, cytogenetic, and molecular genetic investigations on affected cells were pursued. Read More

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January 2022

Perineal warty plaques: A case of verrucous porokeratosis.

Indian J Sex Transm Dis AIDS 2021 Jul-Dec;42(2):159-162. Epub 2021 Jul 27.

Department of Pathology, Dr. RML Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Nonvenereal genital dermatoses form an important category of disorders, and verrucous porokeratosis is a rare and less recognized entity among the same. We present the case of a young adult male with warty growths over scrotum and buttocks for a year. Characteristic cornoid lamellae with typical differentiating features were seen in the histopathology, establishing the diagnosis. Read More

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Grenz ray therapy in disseminated superficial actinic porokeratosis: A case series of 17 patients.

Australas J Dermatol 2022 Feb 14;63(1):91-94. Epub 2021 Dec 14.

Radiotherapy Clinic, Skin Health Institute, Carlton, Victoria, Australia.

The treatments available for disseminated superficial actinic porokeratosis (DSAP) have been limited and have variable efficacy. We report the largest case series to date of the use of Grenz ray therapy in 17 patients with DSAP. There was at least 50% improvement in DSAP lesions in all cases. Read More

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February 2022

Porokeratosis of the Nail Unit: Case Series and Review.

Skin Appendage Disord 2021 Nov 25;7(6):489-492. Epub 2021 May 25.

Department of Dermatology, Medical School, University of São Paulo, São Paulo, Brazil.

Background: The lesions of porokeratosis (PK) lead to skin atrophy and scarring as long as they spread centrifugally. PK affecting the nail unit is seldom described.

Objective: The aim was to revise the previously reported cases of ungual PK and to present 3 new cases. Read More

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November 2021

Porokeratosis: An enigma beginning to unravel.

Indian J Dermatol Venereol Leprol 2021 Nov 17:1-9. Epub 2021 Nov 17.

Talwar Skin Centre, Lucknow, Uttar Pradesh, India.

Porokeratosis is a keratinization disorder with unclear etiopathogenesis, varied clinical presentation and characteristic histopathology, and is usually unresponsive to current therapeutic options. Until now, it was considered to be a clonal disorder with immunity, ultra violet radiation and other factors playing important roles in etiopathogenesis. It is now known that abnormalities in the mevalonate pathway are responsible for this clonal keratinization abnormality. Read More

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November 2021

Novel missense mutations of MVK and FDPS gene in Chinese patients with disseminated superficial actinic porokeratosis.

Clin Chim Acta 2021 Dec 28;523:441-445. Epub 2021 Oct 28.

Department of Dermatology, The Second Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China. Electronic address:

Background And Aims: Porokeratosis (PK) is a heterogeneous group of cutaneous keratinization disorders and has five clinical subtypes. DSAP is the most common clinical subtype and is characterized by multiple small, annular, anhidrotic, keratotic lesions predominantly on sun-exposed areas of the skin. It is an autosomal dominantly inherited epidermal keratinization disorder. Read More

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December 2021

[CME Dermatology 24/Answers: Porokeratosis].

Praxis (Bern 1994) 2021 ;110(14):787-788

Institut für Dermatologie und Venerologie, Stadtspital Zürich.

CME Dermatology 24/Answers: Porokeratosis Porokeratoses are a heterogeneous group of cornification disorders with the characteristic histological feature of the cornoid lamellae in the area of the marginal ridge. It is a rare but characteristic disease that occurs primarily in adulthood. Men are slightly more likely to be affected. Read More

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October 2021

A Case Report of Porokeratosis Ptychotropica in a Chinese Man.

Clin Cosmet Investig Dermatol 2021 7;14:1449-1451. Epub 2021 Oct 7.

Department of Dermatology, The Fifth People's Hospital of Hainan Province, Branch of National Clinical Research Center for Skin and Immune Disease, Haikou, Hainan, People's Republic of China.

Porokeratosis ptychotropica is a rare form of porokeratosis characterized by dyskeratotic skin lesions around genital area or gluteal cleft. Herein, a case of porokeratosis ptychotropica was reported. The patient was a 35-year-old man, who complained of pruritic papules and plaques in the perianal and buttock region for thirteen years. Read More

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October 2021

[CME Dermatology 24: Porokeratosis].

Praxis (Bern 1994) 2021 Sep;110(13):709-716

Institut für Dermatologie und Venerologie, Stadtspital Zürich.

CME Dermatology 24: Porokeratosis Porokeratoses are a heterogeneous group of cornification disorders with the characteristic histological feature of the cornoid lamellae in the area of the marginal ridge. It is a rare but characteristic disease that occurs primarily in adulthood. Men are slightly more likely to be affected. Read More

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September 2021

Pembrolizumab associated Stevens-Johnson syndrome with porokeratosis in a patient in the setting of primary hepatocellular carcinoma.

Australas J Dermatol 2022 Feb 31;63(1):e71-e74. Epub 2021 Aug 31.

Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Pembrolizumab is a humanised therapeutic antibody against the PD-1 receptor. It has been used in various advanced cancer immunotherapies. Here, we report an extremely rare case of a 32-year-old man who developed Stevens-Johnson syndrome (SJS) with porokeratosis simultaneously during pembrolizumab treatment for primary hepatocellular carcinoma (T3N1M1). Read More

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February 2022

Successful Clearance of Linear Porokeratosis With Aminolevulinic Acid and Pulsed Dye Laser.

Dermatol Surg 2021 09;47(9):1300-1301

Department of Dermatology, University of New Mexico, School of Medicine, Albuquerque, New Mexico.

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September 2021

A Case of Solitary Labial Porokeratosis Extending into Oral Mucosa Treated with Topical 5-Fluorouracil.

Indian Dermatol Online J 2021 Jul-Aug;12(4):611-613. Epub 2021 Jul 14.

Department of Dermatology, Venereology and Leprosy, Government Medical College, Nagpur, Maharashtra, India.

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Successful treatment of disseminated superficial actinic porokeratosis with topical 2% cholesterol/ 2% lovastatin cream: a case series with 7 patients.

J Eur Acad Dermatol Venereol 2022 Jan 8;36(1):e52-e54. Epub 2021 Sep 8.

Department of Dermatology and Allergy, School of Medicine, Technical University of Munich, Munich, Germany.

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January 2022

Localized eruptive porokeratosis in pediatric patients following treatment of acute leukemia.

Pediatr Dermatol 2021 Sep 21;38(5):1226-1232. Epub 2021 Aug 21.

Department of Dermatology, Phoenix Children's Hospital, Phoenix, AZ, USA.

Porokeratosis is a rare diagnosis in the pediatric population, and eruptive disease has been documented prior in patients with history of stem cell transplantation. Comparing various porokeratosis eruptions between patients can be difficult due to limitations in current classification and nomenclature. Here, we discuss a single-institution case series of three children who developed porokeratosis following hematopoietic stem cell transplantation for acute leukemia, and we propose that this presentation be termed localized eruptive porokeratosis (LEP). Read More

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September 2021

Eruptive pruritic papular porokeratosis.

Postepy Dermatol Alergol 2021 Feb 10;38(2):167-169. Epub 2021 Mar 10.

Department of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.

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February 2021

Rare case of bullous pemphigoid occurring on atrophic centers of disseminated superficial porokeratosis lesions.

J Dermatol 2021 Nov 18;48(11):e530-e531. Epub 2021 Aug 18.

Department of Dermatology, School of Medicine, WonKwang University, Iksan, Korea.

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November 2021