192 results match your criteria Porcelain Gallbladder

A Unique Presentation of Metastatic Gallbladder Carcinoma.

Case Rep Surg 2021 16;2021:6455540. Epub 2021 Dec 16.

Saint Louis University School of Medicine, USA.

Gallbladder carcinoma can be challenging to diagnose and treat and usually leads to poor outcome, due to its aggressive nature and the nonspecific clinical presentation at early stage. We describe an interesting case of a 60-year-old female who presented with stage 3 appendiceal carcinoma after appendectomy was performed outside hospital. Further imaging workup demonstrated enlarged ovarian cysts and porcelain gallbladder. Read More

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December 2021

CT Imaging Findings of Porcelain Gallbladder and Epiploic Appendagitis: Two Rare Abdominal Pathologies in an Asymptomatic Patient.

Cureus 2021 Jun 10;13(6):e15578. Epub 2021 Jun 10.

Trauma & Critical Care Surgery, Wellspan York Hospital, York, USA.

Porcelain gallbladder (PG) and epiploic appendagitis (EA) are rare imaging findings in an asymptomatic patient. The clinical presentation of PG and EA can vary; however, a common presenting complaint is abdominal discomfort. We describe the case of a 54-year-old male with computerized tomography findings consistent with PG and EA. Read More

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Management of Porcelain Gallbladder, Its Risk Factors, and Complications: A Review.

Diagnostics (Basel) 2021 Jun 10;11(6). Epub 2021 Jun 10.

Department of Infectious Diseases, St. Luke's International Hospital, Tokyo 104-8560, Japan.

The porcelain gallbladder condition describes gallbladder calcification. While gallbladder calcification is believed to increase the risk of developing gallbladder cancer, recent reports have shown that the malignancy risk is much lower than previously reported. Symptomatic patients with porcelain gallbladder should be recommended for cholecystectomy, but the management of asymptomatic patients is debatable. Read More

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Primary clear cell carcinoma of gallbladder arising in porcelain gallbladder.

BMJ Case Rep 2021 Apr 1;14(4). Epub 2021 Apr 1.

Diagnostic and Interventional Radiology, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.

Gallbladder carcinomas (GBCs) are the most common carcinomas of the biliary tract. The clear cell variant is encountered rarely, accounting for approximately 1% of all GBCs.Due to its rarity, the exact incidence and pathogenesis of this variant are unknown. Read More

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Large gallstone initially diagnosed as porcelain gallbladder with malignant change.

Postgrad Med J 2021 Feb 4. Epub 2021 Feb 4.

Department of General Surgery, Tan Tock Seng Hospital, Singapore.

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February 2021

Gallbladder Disorders: A Comprehensive Review.

Dis Mon 2021 Jul 18;67(7):101130. Epub 2021 Jan 18.

Section of Digestive Diseases, Yale New Haven Health System, Yale Center for Pancreatitis, Yale School of Medicine, 333 Cedar Street-1080 LMP, New Haven, CT 06520-8019, USA. Electronic address:

Gallbladder disorders encompass a wide breadth of diseases that vary in severity. We present a comprehensive review of literature for the clinical presentation, pathophysiology, diagnostic evaluation, and management of cholelithiasis-related disease, acute acalculous cholecystitis, functional gallbladder disorder, gallbladder polyps, gallbladder hydrops, porcelain gallbladder, and gallbladder cancer. Read More

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Eine (unbemalte) japanische Porzellanvase als Gallenblase.

MMW Fortschr Med 2020 12;162(21-22):32-33

FA f. Innere Medizin, München, Deutschland.

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December 2020

Incidence and Preoperative Predictor Factors of Gallbladder Cancer Before Laparoscopic Cholecystectomy: a Systematic Review.

J Gastrointest Cancer 2021 Mar 23;52(1):68-72. Epub 2020 Sep 23.

Department of Visceral Surgery, Fattouma Bourguiba Hospital, Monastir, Tunisia.

Introduction: Many cases of gallbladder cancer (GBC) were made incidentally after cholecystectomy for presumed benign disease. The aim of this review is to assess the preoperative predictor factors of gallbladder cancer.

Methods: This systematic review was conducted according to PRISMA guidelines when it was applicable. Read More

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Porcelain Gallbladder.

Clin Gastroenterol Hepatol 2021 12 20;19(12):A30. Epub 2020 Aug 20.

Department of General Internal Medicine, Okayama City Hospital, Okayama, Japan.

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December 2021

Clinical Outcomes of Patients with Porcelain Gallbladder Diagnosed on CT.

Acad Radiol 2021 11 4;28 Suppl 1:S22-S28. Epub 2020 Aug 4.

Division of Abdominal Imaging, Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215; Harvard Medical School, Boston, Massachusetts. Electronic address:

Purpose: To evaluate diagnostic accuracy and clinical outcomes of patients with porcelain gallbladder (GB) diagnosed on CT.

Materials And Methods: In this IRB-approved, HIPAA-compliant study, consecutive patients with porcelain gallbladder reported on CT between December 1, 2000 and August 31, 2017 in a tertiary academic center were included. Two radiologists independently reviewed CT images and confirmed presence of porcelain gallbladder. Read More

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November 2021

A Rare Case of Simultaneous Intrahepatic and Porcelain Gallbladder: Case Report.

Int Med Case Rep J 2020 15;13:271-274. Epub 2020 Jul 15.

Department of Surgery, Islamic Azad University of Medical Sciences, Tehran, Iran.

Intrahepatic gallbladder is a rare anomaly that is due to the failure of gallbladder migration from liver to its proper position. This condition increases the risk of cholelithiasis, hepatic abscess and cholangiocarcinoma. Calcification in the wall of the gallbladder, which is known as porcelain gallbladder, also increases the risk of malignancy. Read More

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Diagnostic Approach to Benign and Malignant Calcifications in the Abdomen and Pelvis.

Radiographics 2020 May-Jun;40(3):731-753. Epub 2020 Apr 17.

From the Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, St Louis, MO 63110.

Intra-abdominal calcifications are common. Multiple pathologic processes manifest within the abdomen and pelvis in association with calcifications, which can be benign, premalignant, or malignant. Although calcium deposition in the abdomen can occur secondary to various mechanisms, the most common cau se is cellular injury that leads to dystrophic calcifications. Read More

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A pictorial review of gall stones and its associated complications.

Clin Imaging 2020 Apr 28;60(2):228-236. Epub 2019 Nov 28.

Department of Diagnostic Radiology, Bridgeport Hospital at Yale New Haven Health, 167 Grant St, Bridgeport, CT 06610, USA.

Gallstone disease is the term commonly used to refer to gallstones that cause symptoms. There is a myriad of complications that can arise from gallstones: acute cholecystitis, xanthogranulomatous cholecystitis, emphysematous cholecystitis, gallbladder wall perforations, pericholecystic abscesses, Mirizzi syndrome, cholecystoenteric fistulas, choledocholithiasis, gallstone pancreatitis, porcelain gallbladder, gallbladder malignancies, and many more. The aim of this pictorial review is to revisit how multimodality imaging can help with the diagnosis of gallstone disease. Read More

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Rates of hypercalcemia and hyperparathyroidism among patients with porcelain gallbladder.

Am J Surg 2020 07 7;220(1):127-131. Epub 2019 Oct 7.

Mayo Clinic, Department of Surgery, USA. Electronic address:

Background: Porcelain gallbladder is characterized by calcification of the gallbladder wall, possibly associated chronic inflammation from cholelithiasis. It is unknown whether porcelain gallbladder is associated with higher rates of hypercalcemia and/or hyperparathyroidism compared to cholelithiasis without porcelain gallbladder.

Methods: We searched our patient database for patients with porcelain gallbladder on imaging and patients with cholelithiasis without porcelain gallbladder. Read More

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Interventional radiology's role in the diagnosis and management of patients with gallbladder carcinoma.

Chin Clin Oncol 2019 Aug 5;8(4):40. Epub 2019 Aug 5.

Department of Radiology, Division of Interventional Radiology, Weill Cornell Medicine, New York, NY, USA.

Gallbladder carcinoma is a rare, aggressive biliary tract malignancy, with a 5-year survival of less than 5%. It is the 6th most common gastrointestinal malignancy in the United States and more commonly found in women. While some risk factors include gallstones, porcelain gallbladder, and smoking, gallbladder carcinoma is often found incidentally following cholecystectomy or percutaneous image guided biopsy. Read More

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Porcelain Gallbladder: A Case Report.

Mymensingh Med J 2019 Jul;28(3):694-698

Professor Md Mohsen Chowdhury, Professor & Head of Yellow Unit II, Department of Hepatobiliary & Pancreatic Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail:

"Porcelain gallbladder" term has been used to highlight the blue staining and fragile consistency of the gallbladder wall at surgery. Some authorities avoid these terms and alternately call all calcified gallbladders "porcelain gallbladders". It is a morphological deviation of chronic cholecystitis. Read More

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Six-Year-Old Girl with Porcelain Gallbladder.

Soon Chul Kim

J Korean Med Sci 2019 05 27;34(20):e152. Epub 2019 May 27.

Department of Pediatrics, Chonbuk National University Children's Hospital, Chonbuk National University Medical School, Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.

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Calcified gallbladder cancer: is it preventable?

J Surg Case Rep 2019 Mar 22;2019(3):rjz069. Epub 2019 Mar 22.

General Surgery Department, West Hertfordshire Hospitals NHS Trust, UK.

A case of a newly diagnosed calcified gallbladder cancer is presented, who had pre-existing porcelain gallbladder. Due to the advanced stage of the disease at presentation, the patient had a poor outcome. The investigation and management of gallbladder carcinoma is discussed as well as the relationship with porcelain gallbladder. Read More

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Cholecystoduodenal fistula caused by aggressive mucinous gallbladder carcinoma with a porcelain gallbladder.

Clin J Gastroenterol 2019 Oct 27;12(5):460-465. Epub 2019 Mar 27.

Division of Gastroenterology, Shinko Hospital, 1-4-47 Wakihama-cho, Chuo-ku, Kobe, Hyogo, 651-0072, Japan.

Cholecystoduodenal fistula secondary to gallbladder carcinoma (GBC) is extremely rare and develops when the tumor penetrates into the adjacent duodenum. A porcelain gallbladder is also a very rare entity that involves the calcification of the gallbladder wall and can be associated with the development of GBC. Herein, we report an unusual case of a patient with cholecystoduodenal fistula, which has been caused by aggressive mucinous gallbladder carcinoma with a porcelain gallbladder. Read More

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October 2019

Prospective observational study on cholelithiasis in patients with carcinoma gall bladder in a tertiary referral hospital of Eastern India.

J Cancer Res Ther 2019 Jan-Mar;15(1):153-156

Department of Surgery, IPGMER/SSKM Hospital; Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, West Bengal, India.

Context: Gallbladder carcinoma (GBCA) is the fifth most common types of gastrointestinal malignancy and is the most common malignancy of the biliary tract. Cholelithiasis, gallbladder polyps, porcelain gall, and choledochal cysts are common known associations with GBCA. Because of the better understanding of the etiopathogenesis, the traditional nihilistic attitude toward the prognosis has, over the years, given way to greater interest and hope for treating the disease. Read More

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Bile Duct Hamartoma Mimicking Liver Metastasis in Suspected Porcelain Gallbladder: a Case Report.

J Gastrointest Cancer 2019 Dec;50(4):1022-1025

Department of General Surgery, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India.

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December 2019

Dysplasia in Gallbladder: What Should We Do?

J Gastrointest Surg 2019 04 13;23(4):686-689. Epub 2018 Sep 13.

Department of Pathology and Immunology, Washington University in St. Louis, 660 S. Euclid Ave, CB: 8118, St. Louis, MO, 63110, USA.

Introduction: On occasional cholecystectomies, pathologists encounter incidental dysplasia in the gallbladder mucosa in the sections submitted per protocol for histologic examination. If dysplasia is identified, additional sections are taken and/or the gallbladder is entirely submitted to rule out underlying adenocarcinoma. The aim of our study was to assess the incidence of subsequent identification of invasive adenocarcinoma on additional sections, after an incidentally detected dysplasia was noted on a routine cholecystectomy section. Read More

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Metformin treatment prevents gallstone formation but mimics porcelain gallbladder in C57Bl/6 mice.

Eur J Pharmacol 2018 Aug 5;833:165-172. Epub 2018 Jun 5.

Department of Pharmacology and Toxicology, Shiraz School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Gallstone disease (GD) is highly correlated with metabolic syndrome and its related illnesses including type II diabetes (DMII) and polycystic ovary syndrome (PCOS). While previous studies claimed that metformin decreases the chance of developing GD in PCOS patients, this phenomenon has not been investigated in animal models to date. Here we fed a high fat diet (HFD) containing 2% of cholesterol and 1% of cholic acid to ten-week-old male C57Bl/6 mice for 105 days. Read More

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Invited Commentary.

J Am Coll Surg 2018 06;226(6):1069-1071

New Haven, CT.

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Trends of Gallbladder Cancer in Jordan Over 2 Decades: Where Are We?

Clin Med Insights Case Rep 2018 20;11:1179547618771699. Epub 2018 Apr 20.

Department of Pathology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Background And Study Aims: The prevalence of gallbladder cancer (GBC) varies between different parts of the world. This study is a review of literature and an update of a previously published study conducted in our university and aims to reassess the incidence of GBC over the past 2 decades.

Patients And Methods: We conducted a retrospective study between 2002 and 2016. Read More

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Routine histopathological study of cholecystectomy specimens. Useful? A retrospective study of 1960 cases.

Acta Gastroenterol Belg 2017 Jul-Sep;80(3):365-370

University of Tunis El Manar, Tunis Faculty of Medicine, Tunisia.

Background And Aims: Traditionally, a gallbladder removed for presumed benign disease is sent for histopathological examination, but this practice has been the subject of controversy.

Aim: The aim of this study was to assess the usefulness of routine histopathological examination of cholecystectomy specimens and its impact on the management of patients.

Patients And Methods: The histopathological reports of 1960 patients who underwent cholecystectomy from January 2011 to November 2016 were retrospectively reviewed. Read More

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Porcelain Gallbladder: Is Observation a Safe Option in Select Populations?

J Am Coll Surg 2018 06 2;226(6):1064-1069. Epub 2018 Mar 2.

Department of General Surgery, Lahey Hospital and Medical Center, Tufts University School of Medicine, Burlington, MA. Electronic address:

Background: Management of gallbladder wall calcifications has been controversial for many decades. Although the traditionally perceived strong association with gallbladder cancer mandated prophylactic cholecystectomy, newer evidence suggests a much lesser association and might indicate an observational approach.

Study Design: A retrospective cohort study of 113 patients with gallbladder wall calcifications diagnosed between 2004 and 2016 at a single institution was conducted. Read More

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Porcelain Gallbladder.

Euroasian J Hepatogastroenterol 2017 Jul-Dec;7(2):181-182. Epub 2017 Sep 29.

Department of General Surgery, Santosh Medical College and Hospital, Ghaziabad, Uttar Pradesh, India.

Porcelain gallbladder or calcified gallbladder is a rare entity and is considered as the end stage of chronic cholecystitis. This disease is rarely diagnosed preoperatively and usually mimics carcinoma gallbladder. Hereby, we present a rare and interesting case of porcelain gallbladder that was diagnosed preoperatively and managed by cholecystectomy. Read More

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September 2017

Porcelain Gallbladder: Often an Overlooked Entity.

Surg J (N Y) 2017 Oct 14;3(4):e145-e147. Epub 2017 Sep 14.

Radiology Department, Colchester General Hospital, CHUFT, Colchester, United Kingdom.

 Porcelain gallbladder (GB) is a rare but potentially premalignant condition with minimal symptoms. Accident and Emergency (A&E) departments often tend to investigate abdominal pain through plain radiographs, which are occasionally reported by radiologists, thereby leaving behind few uncommon conditions, such as porcelain gallbladder unreported.  We present three cases of porcelain GB in which initial diagnosis was not considered due to the presence of various other calcifications in the upper abdomen. Read More

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October 2017