1,657,393 results match your criteria Population Health Metrics [Journal]


The Usefulness of Muscle Biopsy in Initial Diagnostic Evaluation of Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes.

Yonsei Med J 2019 Jan;60(1):98-105

Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.

Purpose: The disease entity mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is characterized by an early onset of stroke-like episodes. MELAS is the most dominant subtype of mitochondrial disease. Molecular genetic testing is important in the diagnosis of MELAS. Read More

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January 2019

Correlation of UGT2B7 Polymorphism with Cardiotoxicity in Breast Cancer Patients Undergoing Epirubicin/Cyclophosphamide-Docetaxel Adjuvant Chemotherapy.

Yonsei Med J 2019 Jan;60(1):30-37

Department of Thyroid and Breast Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Purpose: The present study aimed to investigate correlations between uridine glucuronosyltransferase 2B7 (UGT2B7) -161 single nucleotide polymorphism C to T (C>T) and the occurrence of cardiotoxicity in Chinese breast cancer (BC) patients undergoing epirubicin/cyclophosphamide-docetaxel (EC-D) adjuvant chemotherapy.

Materials And Methods: 427 BC patients who had underwent surgery were consecutively enrolled in this prospective cohort study. All patients were scheduled to receive EC-D adjuvant chemotherapy regimen, and they were divided into UGT2B7 -161 CC (n=141), UGT2B7 -161 CT (n=196), and UGT2B7 -161 TT (n=90) groups according to their genotypes. Read More

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January 2019

Antineutrophil Cytoplasmic Antibody-Associated Vasculitis in Korea: A Narrative Review.

Yonsei Med J 2019 Jan;60(1):10-21

Division of Rheumatology, Department of Internal Medicine, and Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Korea.

Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a group of systemic necrotising vasculitides, which often involve small vessels, and which lead to few or no immune deposits in affected organs. According to clinical manifestations and pathological features, AAV is classified into three variants: microscopic polyangiitis, granulomatosis with polyangiitis (GPA), and eosinophilic GPA. The American College of Rheumatology 1990 criteria contributed to the classification of AAV, although currently the algorithm suggested by the European Medicines Agency in 2007 and the Chapel Hill Consensus Conference Nomenclature of Vasculitides proposed in 2012 have encouraged physicians to classify AAV patients properly. Read More

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January 2019

Porcine-Derived Biomaterials in Tissue Engineering and Reconstructive Surgery: Considerations and Alternatives in Muslim Patients.

J Tissue Eng Regen Med 2018 Dec 16. Epub 2018 Dec 16.

Department of Plastic Surgery, Hand Surgery and Burn Centre, Faculty of Medicine, RWTH University Hospital, Aachen, Germany.

During the last three decades, tissue engineering and reconstructive surgery have become standard therapeutic options in the world of medicine. Several biomaterials, either alone, or in combination with cultured cellular products, have been introduced to compensate for the scarcity of autologous donor tissue or to improve healing in a variety of surgical specialties e.g. Read More

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December 2018

Mortality Trends of Liver Diseases from 1981 to 2016 and the Projection to 2035 in Taiwan: An Age-Period-Cohort Analysis.

Liver Int 2018 Dec 16. Epub 2018 Dec 16.

Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.

Background: Projections on liver diseases mortality can provide a basis for evaluating the World Health Organization's "25 by 25" goal and can help health care systems design appropriate control strategies. This study evaluated whether the 25 by 25 goal can be achieved in Taiwan and discussed possible future control strategies.

Methods: Age-period-cohort models are used to estimate the mortality trends of liver diseases from 1981 to 2016 and project these trends to 2035. Read More

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December 2018

Maternal anaemia and maternal, foetal and neonatal outcomes in a prospective cohort study in India and Pakistan.

BJOG 2018 Dec 16. Epub 2018 Dec 16.

Thomas Jefferson University, 130 S 9th St, Philadelphia, PA, 19107, USA.

Objective: To describe the association of maternal anaemia with maternal, foetal and neonatal outcomes.

Design: Prospective cohort study.

Setting: Rural India and Pakistan. Read More

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December 2018

Serum adipocyte fatty acid-binding protein levels: an indicator of non-alcoholic fatty liver disease in Chinese individuals.

Liver Int 2018 Dec 16. Epub 2018 Dec 16.

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital; Shanghai Clinical Center for Diabetes; Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 200233, China.

Background & Aims: Serum adipocyte fatty acid-binding protein (A-FABP) is closely correlated to metabolic disorders such as obesity and insulin resistance (IR). Non-alcoholic fatty liver disease (NAFLD) is a typical feature of IR in the liver. The aim of this study was to explore the relationship between serum A-FABP levels and NAFLD. Read More

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December 2018

Dementia-friendly community initiatives: An integrative review.

J Clin Nurs 2018 Dec 16. Epub 2018 Dec 16.

University of Canberra, 3. Stephen Neville.

Aim: To synthesise international research conducted on dementia-friendly community initiatives.

Background: The number of people living with dementia is increasing as a result of population ageing. Impairments related to neurological changes, together with environmental challenges result in disability for people who have dementia. Read More

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December 2018

Genomic insights into the vulnerability of sympatric whitefish species flocks.

Mol Ecol 2018 Dec 16. Epub 2018 Dec 16.

Department of Fish Ecology and Evolution, Centre of Ecology, Evolution and Biogeochemistry, EAWAG Swiss Federal Institute of Aquatic Science and Technology, Seestrasse 79, 6047, Kastanienbaum, Switzerland.

The erosion of habitat heterogeneity can reduce species diversity directly but can also lead to the loss of distinctiveness of sympatric species through speciation reversal. We know little about changes in genomic differentiation during the early stages of these processes, which can be mediated by anthropogenic perturbation. Here, we analyse three sympatric whitefish species (Coregonus spp) sampled across two neighbouring and connected Swiss pre-alpine lakes, which have been differentially affected by anthropogenic eutrophication. Read More

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December 2018

Management and outcomes among patients with mixed hepatocholangiocellular carcinoma: A population-based analysis.

J Surg Oncol 2018 Dec 16. Epub 2018 Dec 16.

Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.

Background: We sought to define the management of mixed hepatocellular carcinoma-intrahepatic cholangiocarcinoma (HCC-ICC) as well as characterize short- and long-term outcomes of patients with mixed HCC-ICC.

Methods: Patients diagnosed with HCC-ICC, HCC, or ICC between 2004 and 2015 were identified from the National Cancer Data Base using the International Classification of Diseases for Oncology codes. Short- and long-term outcomes were assessed using univariate and multivariate analyses. Read More

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December 2018

Is malnutrition associated with postoperative complications in patients with primary bone sarcomas?

J Surg Oncol 2018 Dec 16. Epub 2018 Dec 16.

Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts.

Background: Modifiable risk factors that can be optimized to minimize postoperative complications in patients with bone sarcomas are yet to be identified.

Methods: We retrospectively identified 275 patients aged 18 and older who underwent surgery for primary bone sarcomas who also had albumin values recorded within 4 weeks before surgery. Postoperative complications were defined as infection, hematoma, need for additional surgery, or wound complications. Read More

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December 2018

Debunking a myopic view of nature versus nurture.

Authors:
John L Hopper

Clin Exp Optom 2019 Jan;102(1):1-2

Centre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Carlton, Victoria, Australia.

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January 2019

The role of robotic aortic lymphadenectomy in gynecological cancer: surgical and oncological outcome in a single institution experience.

J Surg Oncol 2018 Dec 16. Epub 2018 Dec 16.

Division of Gynecologic Oncology, Department of Women's and Children's Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Background And Objective: This study aims to investigate the surgical outcomes observed in robotic transperitoneal aortic lymphadenectomy (AL) in gynecological cancer patients.

Methods: Retrospective data were collected and analyzed on 71 patients undergoing robotic surgical procedures for gynecological cancers, including transperitoneal AL, between December 2014 and February 2018 at the Catholic University of the Sacred Heart, Rome, Italy.

Results: Median age of the sample population was 50 years (range, 26-76 years). Read More

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December 2018

Quorum sensing between Gram-negative bacteria responsible for methane production in a complex waste sewage sludge consortium.

Appl Microbiol Biotechnol 2018 Dec 15. Epub 2018 Dec 15.

Department of Biological Functions Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu, Kitakyushu, 808-0196, Japan.

Quorum sensing (QS) plays a key role in activating bacterial functions through small molecules called autoinducers. In this study, the QS of Gram-negative bacteria in waste sewage sludge (WSS) was downregulated by adding the quorum quenching enzyme, AiiM lactonase, which cleaved the acyl-homoserine lactone (AHL) autoinducer signals from Gram-negative bacteria, and subsequently methane production was inhibited by over 400%. The pH was lowered after 2 days in the anaerobic fermentation whereas protease activity at the hydrolysis step was almost the same with or without AiiM. Read More

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December 2018

Autonomous self-fertilization in Linum sulcatum, a native annual with a previously unknown mating system.

J Plant Res 2018 Dec 15. Epub 2018 Dec 15.

Department of Biology, University of Minnesota Duluth, 207A Swenson Science Building, Duluth, MN, 55812, USA.

The mating systems of wild plant populations have profound effects on their genetic structure and evolution, yet remain unknown or incompletely described for many species. One such species, the herbaceous native annual Linum sulcatum Riddell (Linaceae), is thought to be self-compatible, but there has been no experimental evidence to date to support this claim. To assess the breeding system of this species, seeds were collected from wild populations and reared in a controlled environment. Read More

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December 2018

Autism in India: a case-control study to understand the association between socio-economic and environmental risk factors.

Acta Neurol Belg 2018 Dec 15. Epub 2018 Dec 15.

Human Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, Tamil Nadu, 641 046, India.

Autism spectrum disorder is a neurodevelopmental disorder and the cause of autism is still unclear. The aim of this study was to investigate the association of socioeconomic, environmental, pregnancy and newborn-related risk factors among children with autism spectrum disorders. This was a population-based case-control study. Read More

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December 2018

Impact of large-scale tree planting in Yunnan Province, China, on the water supply balance in Southeast Asia.

Environ Monit Assess 2018 Dec 15;191(1):20. Epub 2018 Dec 15.

Chongqing College of Arts and Sciences, Chongqing, 402160, China.

Along with rapid economic development and population growth, anthropogenic disturbances to natural ecosystems increase the progressively worsening environmental problems in and around water resources, making the potential ecological risks more severe and unpredictable. In order to cope with the increasingly serious issues related to the ecological environment and poverty alleviation, the Government of Yunnan in Southwest China launched a large-scale afforestation campaign (plantation forestry) on the Yunnan-Guizhou Plateau, which is the main source of several major river systems in Southeast Asia. In this study, we use GIS to investigate the impacts of a large-scale afforestation on the water storage balance of Southeast Asia. Read More

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December 2018

Translation of basic research in cognitive science to HIV-risk: a randomized controlled trial.

J Behav Med 2018 Dec 15. Epub 2018 Dec 15.

Department of Psychiatry and Behavioral Sciences, University of Washington, 1100 NE 45th Street, Suite 300, Box 354944, Seattle, WA, 98195-4944, USA.

Many people enrolled in drug diversion programs are not receiving evidence-based prevention for HIV or hepatitis. This study translated basic research from cognitive science to increase screening for infection and condom use in this population. A parallel three-condition randomized trial was conducted in a drug diversion sample (N = 358), comparing a memory practice condition with two active control conditions. Read More

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December 2018

College Students' Perception of Current and Projected 30-Year Cardiovascular Disease Risk Using Cluster Analysis with Internal Validation.

Authors:
Dieu-My T Tran

J Community Health 2018 Dec 15. Epub 2018 Dec 15.

School of Nursing, University of Nevada, Las Vegas, 4505 S. Maryland Pkwy, Box 453018, Las Vegas, NV, 89154-3018, USA.

Cardiovascular risk factors in young adults at a national level are less than ideal specifically for hypercholesterolemia, hypertension, and diabetes. Explore college students' perception of their 30-year cardiovascular disease (CVD) risk using cluster analysis technique with internal validation. This is a descriptive and cross-sectional study. Read More

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December 2018
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Rural population mobility, deforestation, and urbanization: case of Turkey.

Environ Monit Assess 2018 Dec 15;191(1):21. Epub 2018 Dec 15.

Department of Forest Engineering, Faculty of Forestry, Çankırı Karatekin University, 18200, Çankırı, Turkey.

The benefits of the forests are well known and are by their existence alone an amenity. Nonetheless, urbanization as one of the most remarkable features of social development has immense effects on forest resources and land use. In this study, it is hypothesized that there are temporal interactions among the rural population dynamics, urbanization, and forest resources. Read More

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December 2018

Interaction of H. pylori with toll-like receptor 2-196 to -174 ins/del polymorphism is associated with gastric cancer susceptibility in southern China.

Int J Clin Oncol 2018 Dec 15. Epub 2018 Dec 15.

Department of Gastroenterology, Changzhou No. 2 People's Hospital, Xinglong Xiang 29, Changzhou, 213000, Jiangsu, China.

Background: Genetic polymorphisms of Toll-like receptors play important roles in gastric carcinogenesis. The aim of this study was to determine the role of TLR2-196 to -174 ins/del polymorphism in gastric cancer susceptibility and prognosis.

Methods: This study included 520 people from southern China. Read More

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December 2018

Relative expression of stress-related genes during acclimation at low temperature of psychrotrophic Oenococcus oeni strains from Patagonian wine.

World J Microbiol Biotechnol 2018 Dec 15;35(1). Epub 2018 Dec 15.

Laboratorio de Microbiología Molecular, Instituto de Microbiología Básica y Aplicada (IMBA), Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Roque Sáenz Peña Nº 352, (B1876BXD), Bernal, Buenos Aires, Argentina.

In the present study, we evaluated the transcriptional response of four stress-related genes in three Oenococcus oeni strains after acclimation at two different temperatures. Gene expression was analyzed at time zero and after 48 h acclimation at 18 and 21 °C. After the acclimation period cells were inoculated into sterile Pinot noir wine and MLF was followed for 25 days to investigate if different acclimation temperatures could influence cell survival and MLF performance. Read More

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December 2018

Perceptions of dietary factors promoting and preventing nephrolithiasis: a cross-sectional survey.

World J Urol 2018 Dec 15. Epub 2018 Dec 15.

Department of Urology, NYU Langone Hospital-Brooklyn, Brooklyn, NY, USA.

Objective: To assess knowledge of both promoting and preventive dietary factors on nephrolithiasis in a diverse patient population. Precipitating factors of kidney stone disease include diet, lifestyle, socioeconomic status, and race/ethnicity. However, patient awareness of these influences is poorly described. Read More

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December 2018

Population pharmacokinetic modeling of sustained release lithium in the serum, erythrocytes and urine of patients with bipolar disorder.

Eur J Clin Pharmacol 2018 Dec 15. Epub 2018 Dec 15.

Département de Psychiatrie et de Médecine Addictologique, AP-HP, HUSLS-LRB-FWD, Paris, France.

Purpose: Lithium (Li), the first-line treatment of bipolar disorder, was first developed as an immediate-release form with a routine therapeutic drug monitoring 12 h after the last dose. In Europe, the most commonly prescribed form is a sustained release (srLi). Yet no pharmacokinetics (PK) study has been published of srLi, administered once a day, in adults. Read More

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December 2018

Cementless revision femoral stems application of press-fit principles and clinical outcomes.

Int Orthop 2018 Dec 15. Epub 2018 Dec 15.

, Rennes, France.

Background: Cementless femoral stems are currently used in revision total hip arthroplasty (THA) with the surgeon choosing between various fixation modes. The outcomes are good in the medium term; however, some failures have been attributed to technical errors during implantation. When the decision has been made to use a press-fit implant, the impact of the surgeon's technique on the functional outcomes have not been explored in-depth. Read More

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December 2018

Administrative healthcare data applied to fracture risk assessment.

Osteoporos Int 2018 Dec 15. Epub 2018 Dec 15.

Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Fracture risk scores generated from population-based administrative healthcare data showed comparable or better discrimination than the Fracture Risk Assessment Tool (FRAX) scores computed without bone mineral density for predicting incident major osteoporotic fracture. Administrative data may be useful to identify individuals at high fracture risk at the population level.

Purpose: To evaluate the discrimination of fracture risk scores defined using inputs available from administrative data for predicting incident major osteoporotic fracture (MOF) and hip fracture (HF) alone. Read More

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December 2018

The perception of psychosocial risks through the HSE questionnaire of a population of neurophysiology technicians: a cross-sectional study.

Clin Ter 2018 Nov-Dec;169(6):e281-e286

Department of Public Health and Infectious Diseases, University of Rome "Sapienza", Rome, Italy.

Objectives: The Neurophysiopathology Technicians (NTs) are exposed to psychosocial risks, exposure to psychosocial risks that cause related work stress has been related to numerous physical and mental illnesses. The aim of this study is to evaluate the perception of psychosocial risks in a population of this population.

Materials And Methods: 54 technicians of Neurophysiopathology were enrolled, consisting of 23 males (42,6 %) and 31 females (57,4 %). Read More

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December 2018

Health status, diseases and vaccinations of the homeless in the city of Palermo, Italy.

Ann Ig 2019 Jan-Feb;31(1):21-34

Department of Science for Health Promotion and Mother-Child Care "G. D'Alessandro", University of Palermo, Palermo, Italy.

Introduction: In Italy, as in the rest of the world, the number of homeless people is increasing considerably. Many of them suffer from chronic conditions, mental health problems and addiction to alcohol, drugs or smoking, and need complex medical care. Their health status is often exacerbated by greater difficulty in accessing primary care. Read More

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December 2018

The Incidence and Risk Factors of Venous Thromboembolism in Patients with Inflammatory Bowel Disease: A Prospective Multicenter Cohort Study.

Digestion 2018 Dec 14:1-9. Epub 2018 Dec 14.

Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan.

Background: Venous thromboembolism (VTE) has been shown to be more frequent in inflammatory bowel disease (IBD) than in the general population in Western studies. However, the actual state of VTE in Asian IBD remains poorly understood.

Aims: To reveal the incidence of VTE in IBD patients in Japan. Read More

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December 2018

The Relationship between Weight Status and Depressive Symptoms in a Population Sample with Obesity: The Mediating Role of Appearance Evaluation.

Obes Facts 2018 Dec 14;11(6):514-523. Epub 2018 Dec 14.

Integrated Research and Treatment Center (IFB) AdiposityDiseases, University Hospital Leipzig, Leipzig, Germany.

Objectives: Identifying the underlying pathways between obesity and depression and which individuals with obesity are at risk for developing depressive symptoms is important for improving prevention and treatment efforts. The current study investigated appearance evaluation as a potential mediator of the relationship between obesity and depression.

Methods: A total of 1,000 participants with a self-reported BMI greater than 30 kg/m2 were interviewed about their experiences with an elevated body weight and completed measures on appearance evaluation and depression. Read More

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December 2018

Topical vancomycin for neurosurgery wound prophylaxis: an interim report of a randomized clinical trial on drug safety in a diverse neurosurgical population.

Authors:

J Neurosurg 2018 Dec 14:1-8. Epub 2018 Dec 14.

OBJECTIVEPostoperative surgical site infections (SSIs) in neurosurgical patients carry a significant risk of increased morbidity and mortality. With SSIs accounting for approximately 20% of nosocomial infections and costing approximately $1.6 billion USD annually, there is a need for additional prophylaxis to improve current standards of care. Read More

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December 2018
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Atlantoaxial fixation using C1 posterior arch screws: feasibility study, morphometric data, and biomechanical analysis.

Authors:

J Neurosurg Spine 2018 Dec 14:1-9. Epub 2018 Dec 14.

OBJECTIVEC1-2 is a highly mobile complex that presents unique surgical challenges to achieving biomechanical rigidity and fusion. Posterior wiring methods have been largely replaced with segmental constructs using the C1 lateral mass, C1 pedicle, C2 pars, and C2 pedicle. Modifications to reduce surgical morbidity led to the development of C2 laminar screws. Read More

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December 2018

The caroticoclinoid foramen in fetal and infantile orbitosphenoid, presphenoid, and sphenoid bones: developmental and neurosurgical considerations.

Authors:

J Neurosurg Pediatr 2018 Dec 14:1-7. Epub 2018 Dec 14.

OBJECTIVEThe presence of a caroticoclinoid foramen may increase the likelihood of adverse neurosurgical events. Despite the clinical importance of the caroticoclinoid foramen, its study has been mostly limited to adult populations. Therefore, the object of this study was to describe the prevalence, morphology, and development of the caroticoclinoid foramen among varied sexes and races in early life. Read More

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December 2018

Evaluation of a more ventral starting point for thoracic pedicle screws: higher maximal insertional arc and more medial and safer screw angulation.

Authors:

J Neurosurg Spine 2018 Dec 14:1-7. Epub 2018 Dec 14.

OBJECTIVETo demonstrate that a more ventral starting point for thoracic pedicle screw insertion, produced by aggressively removing the dorsal transverse process bone down to the superior articular facet (SAF), results in a larger margin for error and more medial screw angulation compared to the traditional dorsal starting point (DSP). The margin for error will be quantified by the maximal insertional arc (MIA).METHODSThe study population included 10 consecutive operative patients with adult idiopathic scoliosis who underwent primary surgery. Read More

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December 2018

Work absence due to compensable RTCs in Victoria, Australia.

Inj Prev 2018 Dec 15. Epub 2018 Dec 15.

School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

Introduction: RTC burden is commonly measured using fatality or hospitalisation statistics. However, non-fatal and less severe injuries contribute substantial economic and human costs, including work absence. In Victoria, Australia, two major compensation systems provide income support to employed people injured in RTCs; workers' compensation (if RTC occurred during work) and an RTC-specific compensation system. Read More

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December 2018

Perceptions of health and healthcare in ex-Army residents of Tameside: a pilot qualitative study.

Authors:
Steven L Senior

J R Army Med Corps 2018 Dec 15. Epub 2018 Dec 15.

Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester M13 9PL, UK

Background: Local authorities and other service providers need data on their local ex-military communities to be able to plan services. However, published research and data may not be applicable to the local population. Qualitative research offers a relatively low-cost way to get insights into the needs of local ex-military communities. Read More

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December 2018

Illicit cigarette trade in Metropolitan Santiago de Chile.

Tob Control 2018 Dec 15. Epub 2018 Dec 15.

Economic and Health Policy Research, American Cancer Society, Atlanta, Georgia, USA.

Objective: To estimate with a rigorous statistical methodology and independent from the tobacco industry the prevalence and consumption of illicit cigarettes in Metropolitan Santiago de Chile, in addition to identifying the variables statistically associated with choosing to smoke illicit cigarettes.

Methods: Surveys of 851 smokers who reside in the Metropolitan Santiago were collected using a sampling design that combined a randomisation of high-traffic points and a quota sampling to approximate the smoking population. Photographs of packs along with questions on where they were bought were used to define whether cigarettes were licit or illicit. Read More

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December 2018

Rates and characteristics of postcolonoscopy colorectal cancer in the Swedish IBD population: what are the differences from a non-IBD population?

Gut 2018 Dec 15. Epub 2018 Dec 15.

Department of Medicine, Solna (MedS), Karolinska Institutet, Stockholm, Sweden.

Objective: The rate of postcolonoscopy colorectal cancer (PCCRC) is considered a key quality indicator of colonoscopy; little is known about PCCRC in IBD.

Design: A population-based cohort study of colonoscopies in Sweden from 2001 to 2010 was conducted. Individuals with a colorectal cancer (CRC) detected within 36 months after a colonoscopy were identified and stratified on UC, Crohn's disease (CD) or non-IBD. Read More

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December 2018

Disruption of periaqueductal grey-default mode network functional connectivity predicts persistent post-traumatic headache in mild traumatic brain injury.

J Neurol Neurosurg Psychiatry 2018 Dec 15. Epub 2018 Dec 15.

Department of Medical Imaging, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

Objective: Post-traumatic headache (PTH) is one of the most frequent and persistent physical symptoms following mild traumatic brain injury (mTBI) and develop in more than 50% of this population. This study aimed to investigate the periaqueductal grey (PAG)-seeded functional connectivity (FC) in patients with mTBI with acute post-traumatic headache (APTH) and further examine whether the FC can be used as a neural biomarker to identify patients developing chronic pain 3 months postinjury.

Methods: 70 patients with mTBI underwent neuropsychological measurements and MRI scans within 7 days postinjury and 56 (80%) of patients were followed up at 3 months. Read More

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December 2018

Relationship between depressive symptom severity and amygdala volume in a large community-based sample.

Psychiatry Res Neuroimaging 2018 Dec 6;283:77-82. Epub 2018 Dec 6.

Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd. MC 8849, Dallas, TX, USA. Electronic address:

Amygdala is an affective processing center that regulates and assigns valence to different emotions and has been implicated in the pathophysiology of mood disorders. This population-based study employed a community sample of 1747 adults to examine relationships between amygdala volume and depressive symptom severity. Neuroimaging data from participants in the Dallas Heart Study were used. Read More

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December 2018

Risk factors for childhood violence and polyvictimization: A cross-country analysis from three regions.

Child Abuse Negl 2018 Dec 13;88:348-361. Epub 2018 Dec 13.

UNICEF Office of Research-Innocenti, Piazza SS Annunziata 12, 50121, Florence, Italy.

Understanding risk factors is important to ending childhood violence and meeting Sustainable Development Goal 16.2. To date, no study has examined patterns of risk factors across countries comprehensively for different types of childhood violence, and there is a dearth of evidence of polyvictimization in lower- and middle-income settings. Read More

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December 2018

Iron-related nigral degeneration influences functional topology mediated by striatal dysfunction in Parkinson's disease.

Neurobiol Aging 2018 Nov 22;75:83-97. Epub 2018 Nov 22.

Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:

In Parkinson's disease (PD), iron accumulation in the substantia nigra (SN) exacerbates oxidative stress and α-synuclein aggregation, leading to neuronal death. However, the influence of iron-related nigral degeneration on the subcortical function and global network configuration in PD remains unknown. Ninety PD patients and 38 normal controls underwent clinical assessments and multimodality magnetic resonance imaging scans. Read More

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November 2018

Gender-specific prevalence of poor sleep quality and related factors in a Chinese rural population: the Henan Rural Cohort Study.

Sleep Med 2018 Nov 22;54:134-141. Epub 2018 Nov 22.

Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, PR China. Electronic address:

Objective: To estimate the prevalence of poor sleep quality and identify related factors by gender in the Chinese rural population.

Methods: Overall, 27424 subjects (10881 males and 16543 females) aged 18-79 years were enrolled from the Henan Rural Cohort Study. Sleep quality was evaluated by the standard Pittsburgh Sleep Quality Index (PSQI) and global score>5 was classified as poor sleep quality. Read More

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November 2018

The relationship between obstructive sleep apnea and insomnia: a population-based cross-sectional polysomnographic study.

Sleep Med 2018 Nov 17;54:126-133. Epub 2018 Nov 17.

Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology (NTNU), N-7491 Trondheim, Norway; Department of Neurology and Clinical Neurophysiology, St. Olavs Hospital, N-7006 Trondheim, Norway.

Background: The relationship between insomnia and objectively measured obstructive sleep apnea (OSA) severity has not previously been investigated in both genders in the general population. The main aim of this population-based polysomnography (PSG) study was to evaluate the cross-sectional association between severity of OSA and DSM-V insomnia and insomnia severity.

Methods: A random sample of 1200 participants in the third Nord-Trøndelag Health Study (HUNT3) was invited and 213 (18%) aged between 21 and 82 years underwent an ambulatory PSG, a semi-structured interview, and a sleep-specific questionnaire. Read More

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November 2018

Association between short-term exposure to particulate matter air pollution and cause-specific mortality in Changzhou, China.

Environ Res 2018 Nov 28;170:7-15. Epub 2018 Nov 28.

Department of Occupational Medicine and Environmental Health, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, PR China; Department of Hygiene Analysis and Detection, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, PR China. Electronic address:

Background: Extensive studies have linked ambient particulate matter (PM) to an increased mortality burden from a wide range of causes. However, the effects of PM on mortality rates from specific causes were unclear. This study aimed to estimate the detrimental effects of PM on cause specific deaths in Changzhou, China. Read More

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November 2018
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Home students' experiences of intercultural learning: A qualitative descriptive design.

Nurse Educ Today 2018 Dec 8;74:25-30. Epub 2018 Dec 8.

University of Limerick, Ireland. Electronic address:

Background: Higher education institutes are witnessing an increase in the cultural and ethnic diversity of their student population. While this adds to the learning experience, there is a dearth of evidence examining how students on nursing programmes, from different cultural and ethnic backgrounds learn with and from each other. There is need for a greater understanding of the factors that both facilitate and inhibit intercultural learning within the classroom. Read More

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December 2018

Occurrence, diversity, and persistence of antibiotic resistant enterococci in full-scale constructed wetlands treating urban wastewater in Sicily.

Bioresour Technol 2018 Dec 8;274:468-478. Epub 2018 Dec 8.

Department of Agriculture, Food and Environment (Di3A), University of Catania, Via Santa Sofia 100, Catania 95123, Italy.

Enterococci isolated from different sites of an urban wastewater treatment plant (consisting of three horizontal subsurface flow constructed wetlands) were investigated. One-hundred-thirty isolates were identified at species level and tested for resistance to eleven antibiotics, by microdilution method, and their clonal relatedness was established by SmaI-PFGE analysis. Results highlighted the persistence of enterococcal population in all effluents and the dominance of E. Read More

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December 2018

Functional outcomes and health-related quality of life following curative treatment for rectal cancer: A population-level study in England.

Int J Radiat Oncol Biol Phys 2018 Dec 13. Epub 2018 Dec 13.

Leeds Institute of Cancer & Pathology, University of Leeds, Leeds LS2 9LN.

Background: There is a growing population of cancer survivors at risk of treatment-related morbidity. This study investigates how potentially curative rectal cancer treatment influences subsequent function and health-related quality of life (HRQL) using data from a large-scale survey of patient-reported outcomes.

Methods: All individuals 12-36 months post-diagnosis of colorectal cancer in England were sent a survey in January 2013. Read More

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December 2018

Typology of cannabis use among adults: A latent class approach to risk and protective factors.

Addict Behav 2018 Dec 10;92:6-13. Epub 2018 Dec 10.

University of Houston, Department of Psychology, Houston, TX, United States; The University of Texas MD Anderson Cancer Center, Department of Behavioral Science, Houston, TX, United States. Electronic address:

Background: Cannabis is among the most widely used substances worldwide. The United States has seen an increase in the number of adult daily cannabis users and in the number of adults diagnosed with cannabis use disorder. However, little work has examined patterns of use or unique subgroups of adult cannabis users, which may be useful in developing targeted treatment interventions for problematic cannabis users. Read More

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December 2018

Increased cerebral blood flow after single dose of antipsychotics in healthy volunteers depends on dopamine D2 receptor density profiles.

Neuroimage 2018 Dec 13. Epub 2018 Dec 13.

Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 8AF, London, United Kingdom.

As a result of neuro-vascular coupling, the functional effects of antipsychotics in human brain have been investigated in both healthy and clinical populations using haemodynamic markers such as regional Cerebral Blood Flow (rCBF). However, the relationship between observed haemodynamic effects and the pharmacological action of these drugs has not been fully established. Here, we analysed Arterial Spin Labelling (ASL) rCBF data from a placebo-controlled study in healthy volunteers, who received a single dose of three different D2 receptor (DR) antagonists and tested the association of the main effects of the drugs on rCBF against normative population maps of DR protein density and gene-expression data. Read More

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December 2018
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