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Sleep Breath 2019 Feb 19. Epub 2019 Feb 19.

School of Biological Science and Medical Engineering and Research Institute, Beihang University, Shenzhen, China.

Objectives: To determine inter-lab reliability in sleep stage scoring using the 2014 American Academy of Sleep Medicine (AASM) manual. To understand in-depth reasons for disagreement and provide suggestions for improvement.

Methods: This study consisted of 40 all-night polysomnographys (PSGs) from different samples. Read More

Exp Ther Med 2019 Mar 18;17(3):1766-1770. Epub 2018 Dec 18.

Department of Otolaryngology, Xuzhou Central Hospital, Xuzhou, Jiangsu 221009, P.R. China.

The present study investigated the changes of tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8) and sleep ability in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). A total of 684 patients who were admitted to Xuzhou Central Hospital between June 2012 and June 2016 were enrolled to serve as the experimental group and 192 healthy subjects were selected as the control group. Polysomnography was performed on both groups, and serum TNF-α and IL-8 levels were measured by ELISA. Read More

Epileptic Disord 2019 Feb 18. Epub 2019 Feb 18.

Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.

Obstructive sleep apnea affects up to 30% of patients with epilepsy. As obstructive sleep apnea represents a clinical risk factor for cognitive deficits, its occurrence in epilepsy patients may exacerbate cognitive deficits associated with this condition. However, the cognitive burden of obstructive sleep apnea in epilepsy remains poorly understood. Read More

Int J Vitam Nutr Res 2019 Feb 20:1-7. Epub 2019 Feb 20.

3 Department of Neurology, Bahcesehir University, Medical Park Goztepe Hospital, Istanbul, Turkey.

Observational studies performed in homogeneous groups to objectively investigate the cause and effect relationship between vitamin D deficiency and sleep disorders are scarce. In this study, it was aimed to analyze the relationship between the severity of OSAS and vitamin-D levels among the participants whose features affecting serum vit-D levels were minimised. Serum 25-OH vitamin-D levels in 121 OSAS Male patients diagnosed by polysomnography without any systemic disease or vitamin-D supplement that may effect the vitamin-D metabolism were measured. Read More

Health Informatics J 2019 Feb 19:1460458219827349. Epub 2019 Feb 19.

Keio University, Japan.

Getting enough quality sleep plays a vital role in protecting our mental health, physical health, and quality of life. Sleep deprivation can make it difficult to concentrate on daily activities, and lower sleep quality is associated with hypertension, hyperglycemia, and hyperlipidemia. The amount of sleep we get is important, but in recent years, quality sleep has also been deemed significant. Read More

Sleep Med 2019 Jan 6;55:109-114. Epub 2019 Jan 6.

Department of Orthodontics, Adelaide Dental Hospital, Adelaide, Australia.

Background: Residual snoring in children with obstructive sleep disordered breathing (SDB) may continue post-adenotonsillectomy. This study aims to identify baseline dentofacial differences in children with SDB using routine orthodontic records that might aid effective early intervention for the upper airway to prevent continued obstruction.

Methods: Children (6-16 years) with clinically diagnosed SDB from a paediatric Otolaryngology Clinic who required adenotonsillectomy were participants (n = 10). Read More

Psychiatry Res 2019 Feb 6;274:49-57. Epub 2019 Feb 6.

Department of Psychiatry, University of Michigan, Ann arbor, MI, United States.

Melatonin secretion and polysomnography (PSG) were compared among a group of healthy adolescents who were at high familial risk for bipolar disorder (HR) and a second group at low familial risk (LR). Adolescent participants (n = 12) were a mean age 14 ± 2.3 years and included 8 females and 4 males. Read More

Sleep Breath 2019 Feb 18. Epub 2019 Feb 18.

Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Wilrijkstraat 10, 2650, Edegem, Belgium.

Purpose: The aim of the present study was to assess the efficacy of a sleep position trainer (SPT) in patients with an established diagnosis of positional obstructive sleep apnea and to evaluate the adherence after 1-year follow-up.

Methods: Polysomnography (PSG) was performed at baseline and after 1 year of SPT use. Patients received questionnaires to assess treatment satisfaction and subjective adherence. Read More

Vertex 2018 May;XXIX(139):165-171

Sección de Medicina del sueño. Neurología. Hospital Italiano. Hospital Británico. Buenos Aires.

Kleine-Levin syndrome is an uncommon disorder with recurrent episodes of hypersomnia, and behavioral abnormalities such as binge-eating and hypersexuality. Our aims were to report cases of the Kleine-Levin syndrome diagnosed in Buenos Aires, Argentina and to characterize the clinical presentation of these patients. We evaluated patients with Kleine-Levin syndrome according to the International Classification of Sleep Disorders. Read More

Indian J Med Res 2018 Dec;148(6):748-751

Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India.

Narcolepsy is a common sleep disorder in Western countries but rarely reported from India. Here, we report a small case series of four narcolepsy patients seen over a four year period in the sleep clinic of a tertiary care hospital in north India. The diagnosis was established by clinical history and two or more sleep-onset rapid eye movements (SOREMs) on multiple sleep latency tests (MSLTs) following overnight polysomnography (PSG). Read More

J Craniomaxillofac Surg 2019 Feb 5. Epub 2019 Feb 5.

Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong. Electronic address:

Purpose: To compare mandibular distraction osteogenesis (MDO) to sagittal split ramus osteotomy (SSRO) to treat moderate-to-severe obstructive sleep apnea (OSA), and their surgical morbidities and skeletal stability.

Materials And Methods: A randomized clinical trial was conducted on non-syndromic adult patients with apnea-hypopnea index (AHI) 15 or above to receive MDO or SSRO as part or whole skeletal advancement surgery. Post-operative 1 year OSA cure rate (AHI < 5/hour) and treatment success rate (50% reduction of AHI and AHI< 20/hour) were compared. Read More

Sleep Med 2019 Feb 1. Epub 2019 Feb 1.

PériTox, UMR_I 01, Jules Verne University of Picardy, CURS, Présidence UPJV, Amiens, France.

Objective: Prior to sleep onset in human adults, distal body temperatures change progressively from wakefulness levels (low skin temperatures and a high core temperature) to sleep levels (high skin temperatures and a low core temperature) due to distal skin vasodilation and greater body cooling. It is not known whether this sleep preparedness exists in preterm neonates, even though sleep has a key role in neonatal health and neurodevelopment. The present study's objectives were to determine whether sleep preparedness (as observed in adults) can be evidenced in preterm neonates, and to assess repercussions on thermal stress. Read More

Psychiatry Res 2019 Feb 6;274:27-29. Epub 2019 Feb 6.

Department of Neurology, Keimyung University School of Medicine, Dongsan Medical Center, School of Medicine, 56 Dalseong-ro, Jung-gu, Daegu 41931, South Korea. Electronic address:

We surveyed patients the next morning after in-laboratory polysomnography (PSG) to compare the first night effect (FNE) and reverse first night effect (RFNE) in different sleep disorders. A questionnaire was given to 852 patients with insomnia (n = 171), restless legs syndrome (n = 186), obstructive sleep apnea (n = 369), simple snoring (n = 54), REM sleep behavior disorder (n = 39), and hypersomnia (n = 33). FNE was seen in 48. Read More

Acta Otolaryngol 2018 Nov;138(11):1009-1013

c Pediatric Otolaryngology , Seattle Children's Hospital , Seattle , WA , USA.

Background: Children with Down Syndrome (DS) and obstructive sleep apnea (OSA) are difficult to treat, as first line therapies may not lead to significant improvement. Drug-induced sleep endoscopy (DISE) directed surgery may be particularly beneficial for these patients.

Objective: To assess change in polysomnography (PSG) measures of patients with DS who underwent DISE-directed surgery. Read More

Clin Neurophysiol 2019 Feb 6;130(4):505-514. Epub 2019 Feb 6.

University of Oxford, Institute of Biomedical Engineering, Dept. Engineering Sciences, Oxford, UK.

Objective: Evidence suggests Rapid-Eye-Movement (REM) Sleep Behaviour Disorder (RBD) is an early predictor of Parkinson's disease. This study proposes a fully-automated framework for RBD detection consisting of automated sleep staging followed by RBD identification.

Methods: Analysis was assessed using a limited polysomnography montage from 53 participants with RBD and 53 age-matched healthy controls. Read More

Sleep Med 2018 Dec 18;55:62-68. Epub 2018 Dec 18.

Department of Neurology, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal; CEDOC, Chronic Diseases Research Center, NOVA Medical School, USA.

Introduction: Sleep dysfunction is frequent in Dementia with Lewy Bodies (DLB), but polysomnographic (PSG) data is scarce. Our objectives were to: (1) compare PSG data between DLB patients and age normative values (NV), Parkinson's Disease (PD) and idiopathic REM sleep behavior disorder (iRBD) patients; (2) evaluate the relation between of OSA, Fluctuations and Hypersomnolence and PSG data.

Methods: We selected all consecutive patients with DLB, PD and iRBD that underwent video-PSG during a two year period. Read More

Sleep Med 2018 Dec 19;55:100-108. Epub 2018 Dec 19.

University of Warwick, Department of Psychology, University Road, CV4 7AL, United Kingdom.

Objectives: The present study explored associations between sleep and children's dual-task performance using cognitive-motor dual tasks (eg, walking and talking). Previous research with older adults indicated correlations between higher gait variability and unfavorable sleep continuity variables. Based on this research, as a first objective, we investigated similar correlations in a sample of children. Read More

Int J Pediatr Otorhinolaryngol 2019 Feb 5;120:108-111. Epub 2019 Feb 5.

Medical University of Warsaw, Faculty of Medicine and Dentistry, Department of Otorhinolaryngology, Poland.

Study Objectives: The purpose of this work is to present available questionnaires enabling diagnostic screening when obstructive sleep disordered breathing (SDB) in a child is suspected or its effects are observed and polysomnography is unavailable. These questionnaires are designed to facilitate further diagnostic process or even therapeutic decisions, aid in selecting the optimal one for the specified conditions of clinical practice, with the caveat that none of these represents a diagnostic equivalent to PSG.

Methods: The questionnaires subjected to analysis: Pediatric Sleep Questionnaire (PSQ), Sleep Clinical Record (SCR), OSA-18 score (OSA-18), Brouilette score (BS), "I'm Sleepy" questionnaire (I'M SLEEPY), and "Sleeping Sleepless Sleepy Disturbed Rest" questionnaire (SSSDR). Read More

Brain Behav 2019 Feb 14:e01220. Epub 2019 Feb 14.

Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China.

Objectives: To compare the sleep characteristics and cognition between rapid eye movement sleep behavior disorder (RBD) patients and non-RBD (nRBD) healthy control subjects and to determine the correlation between sleep and cognition in RBD patients.

Methods: Polysomnography (PSG) was performed to confirm and exclude RBD. Fifteen iRBD patients, 12 PD with RBD patients, and 23 matched nRBD healthy control subjects were enrolled. Read More

J Clin Med 2019 Feb 5;8(2). Epub 2019 Feb 5.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

The association between sleep apnea (SA) and peripheral artery disease (PAD) remains debatable, and there is no clinical tool to predict incident PAD in SA patients. The CHADS₂ score has been found useful in predicting PAD risk. This study was designed to investigate the association between these diseases and the usefulness of CHADS₂ and CHA₂DS₂ASc scores in predicting subsequent PAD in SA patients. Read More

Pain Pract 2019 Feb 14. Epub 2019 Feb 14.

Cousins Center for Psychoneuroimmunology, University of California, Los Angeles (UCLA).

Background: Sleep macrostructure is commonly disturbed after surgery. Postoperative pain control remains challenging. Given the bidirectional interaction between sleep and pain, understanding the role of modulation of sleep during the perioperative period on postoperative pain is needed. Read More

Neuropsychobiology 2019 Feb 13:1-9. Epub 2019 Feb 13.

Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada.

Background: A growing body of evidence has linked mental health outcomes to the gut microbiome. This has led to the investigation of the GI tract as a target for novel treatments and interventions for depression, including probiotic supplementation. Our recent pilot study provided the first evidence of probiotics improving symptoms of depression in treatment-naive depressed patients. Read More

Sleep 2019 Feb 12. Epub 2019 Feb 12.

Centre for Cognitive Neuroscience, Duke-NUS Medical School, Singapore.

Study Objectives: Many adolescents are exposed to sleep restriction on school nights. We assessed how different apportionment of restricted sleep (continuous versus split sleep) influences neurobehavioral function and glucose levels.

Methods: Adolescents, aged 15-19 years, were evaluated in a dormitory setting using a parallel-group design. Read More

J Thorac Dis 2018 Dec;10(12):6702-6710

Department of Otorhinolaryngology, Head and Neck Surgery, Juntendo University School of Medicine, Tokyo, Japan.

Background: Childhood obstructive sleep apnea (OSA) has important implications for growth, learning, behavior, cognition and cardiovascular health as well as snoring and OSA in adulthood. In this study, we elucidated the sex differences in polysomnographic (PSG) findings and pharyngeal radiographic data in pediatric OSA patients.

Methods: Sixty three children (age between 3 and 15 years old) with OSA [defined as apnea-hypopnea index (AHI) ≥1/h by polysomnography] were enrolled. Read More

Sleep Sci 2018 Jul-Aug;11(4):269-273

National Institute of Respiratory Diseases, Sleep Medicine Unit - Mexico - Mexico City - Mexico.

Objectives: To: 1) evaluate the quality of an ambulatory monitoring technique for diagnosing Obstructive Sleep Apnea Syndrome (OSAS) while patients move through the city; and 2) identify factors that lead to data loss.

Methods: Clinical histories were reviewed and ambulatory portable monitorings of adults with high pretest probability for OSAS were included, the signals monitored were pulse oximetry, heart rate, nasal pressure, snoring, chest band and body position. The equipment was connected from 14:00-20:00 h and then patients moved through the city turning it off and on at home. Read More

Ann Thorac Med 2019 Jan-Mar;14(1):63-68

Department of Medical Biochemistry, Medical Faculty, Yuzuncu Yil University, Van, Turkey.

Background: Obstructive sleep apnea (OSA) is a common sleep problem, in which patients are at increased risk for metabolic and cardiovascular problems, including metabolic syndrome, diabetes mellitus (DM), and dyslipidemia. Betatrophin is a novel protein that regulates fatty acid and triglyceride (TG) metabolism and is related to obesity and metabolic abnormalities, including metabolic syndrome, DM, and dyslipidemia. Although OSA and betatrophin share common abnormalities, their relationship has not been investigated. Read More

Sleep Med 2019 Jan 23. Epub 2019 Jan 23.

Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada; Women & Children's Health Research Institute, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada; Stollery Children's Hospital, Edmonton, Alberta, Canada. Electronic address:

Aim: To highlight Canada's contributions to the assessment and treatment of pediatric obstructive sleep apnea as well as outline the current state of pediatric obstructive sleep apnea in Canada.

Methods: A search was conducted in MEDLINE (Ovid) using Medical Subject Headings (MeSH) and free-text terms for 'child' and 'obstructive sleep apnea' with subsequent 'human' limit. The results were reviewed to identify publications where any author's listed a Canadian institution. Read More

J Neurol 2019 Feb 11. Epub 2019 Feb 11.

Department of Neurology, Washington University School of Medicine, Saint Louis, MO, USA.

Objectives: Autoimmune encephalitis (AE) is increasingly recognized as an important cause of subacute cognitive decline, seizures, and encephalopathy, with an ever-broadening clinical phenotype. Sleep disturbances are reported in AE patients, including rapid eye movement sleep behavior disorder, hypersomnia, fragmented sleep, and sleep-disordered breathing; however, the prevalence of sleep disturbances and contributions to outcomes in AE patients remain unknown. There is a need to determine the prevalence of sleep disturbances in AE patients, and to clarify the relationship between specific autoantibodies and disruptions in sleep. Read More

J Vis Exp 2019 Jan 26(143). Epub 2019 Jan 26.

Department of Neurology, Washington University School of Medicine; Hope Center for Neurological Disorders, Washington University School of Medicine;

The gold standard for sleep monitoring is attended in-lab polysomnography; however, this method may be cost-prohibitive and inconvenient for patients and research participants. Home sleep testing has gained momentum in the field of sleep medicine due to its convenience and lower cost, as well as being more naturalistic. The accuracy and quality of home sleep testing, however, may be variable because studies are not monitored by sleep technologists. Read More

J Sleep Res 2019 Feb 11:e12830. Epub 2019 Feb 11.

Sleep Unit, Department of Respiratory Medicine, Hospital Universitari de Bellvitge, Hospitalet de Llobregat, Spain.

Central obesity is the main risk factor for obstructive sleep apnea (OSA). Whether there exists a central-obesity anthropometric that better explains apnea-hypopnea index (AHI) variability in the general population and in sleep cohorts is unknown, and this is even less explored among increasing grades of obesity. The objective of the study is to investigate whether there is an anthropometric that better explains AHI variability in a sample of morbidly obese women awaiting bariatric surgery (BS). Read More

J Clin Sleep Med 2019 Feb 4. Epub 2019 Feb 4.

Abstract: The most common sleep disorders that can result in injurious or violent behaviors include REM sleep behavioral disorder, sleepwalking, comorbid parasomnias, sleep-related dissociative disorder, and obstructive sleep apnea. Video polysomnography is usually indicated to evaluate recurring sleep-related injury in adults. Only one-third of patients with complex paroxysmal nocturnal events will have one of their habitual events on a single night of in-laboratory video polysomnography, most often those who have prominent, high-frequency motor features. Read More

J Clin Sleep Med 2019 Feb 4. Epub 2019 Feb 4.

Abstract: Respiratory disorders may follow brain injury and may also occur because of comorbidities and drug use, especially central depressants or muscle relaxants. Sleep can precipitate respiratory disorders, thus polysomnography can be a powerful diagnostic tool. By revealing breathing patterns that identify specific sleep disorders, polysomnography may unmask adverse pharmacological effects, for instance connecting central depressant drugs with central sleep apneas. Read More

J Clin Sleep Med 2019 Feb 4. Epub 2019 Feb 4.

Study Objectives: Overnight pulse oximetry (OPO) is commonly used as a screening test for obstructive sleep apnea. Heart rate variability (HRV) correlates well with apnea-hypopnea index during polysomnography (PSG). We hypothesized that visual correlation of episodic increase in HRV with minimal oxygen desaturations on normal OPO (oxygen desaturation index less than 5 events/h) is predictive of OSA. Read More

J Clin Sleep Med 2019 Feb 4. Epub 2019 Feb 4.

Abstract: Trauma-associated sleep disorder (TASD) is a parasomnia sharing characteristics of post-traumatic stress disorder (PTSD) and REM sleep behavior disorder (RBD) including dream-enactment behavior (DEB). Here we report REM sleep without atonia (RSWA) and other neurological features in a patient with complex vocal and motor DEB following traumatic combat military exposure. Post-discharge, his wife observed frequent yelling and jerking during sleep with dream mentation reminiscent of traumatic military experiences. Read More

J Clin Sleep Med 2019 Feb 4. Epub 2019 Feb 4.

Study Objectives: Evaluation of apnea detection using a tracheal sound (TS) sensor during sleep in patients with obstructive sleep apnea.

Methods: Polysomnographic recordings of 32 patients (25 male, mean age 66.7 ± 15. Read More

J Clin Sleep Med 2019 Feb 4. Epub 2019 Feb 4.

Study Objectives: Apnea-hypopnea index (AHI) is the main polysomnographic measure to diagnose obstructive sleep apnea (OSA). We aimed to evaluate the effect of three standard hypopnea definitions on the prevalence of OSA and its association with cardiometabolic outcomes in the general population.

Methods: We analyzed data from the HypnoLaus study (Lausanne, Switzerland), in which 2,162 participants (51% women, 57 ± 19 years) underwent in-home full polysomnography. Read More

J Clin Sleep Med 2019 Feb 4. Epub 2019 Feb 4.

Study Objectives: Previous research revealed a positive correlation between endothelial cell injury (indicated by albuminuria) and obstructive sleep apnea (OSA). However, little else has been revealed about acute kidney injury (AKI) in patients with OSA.

Methods: This prospective study recruited consecutive patients undergoing overnight polysomnography for evaluation of sleep apnea. Read More

Physiol Meas 2019 Feb 8. Epub 2019 Feb 8.

Stanford Center for Sleep Sciences and Medicine, Stanford University Department of Psychiatry and Behavioral Sciences, Palo Alto, UNITED STATES.

Objective: Obstructive sleep-disordered breathing (SDB) events, unlike central events, are associated with increased respiratory effort. Esophageal pressure (Pes) monitoring is the gold standard for measuring respiratory effort, but it is typically poorly tolerated because of its invasive nature. The objective was to investigate whether machine learning can be applied to routinely collected non-invasive, polysomnography (PSG) measures to accurately model peak negative Pes. Read More

Sleep Breath 2019 Feb 8. Epub 2019 Feb 8.

Department of Child Health, University of Missouri School of Medicine, Columbia, MO, USA.

Purpose: Obstructive sleep apnea (OSA) is very common occurrence among morbidly obese patients. Our main objectives were to validate the No-Apnea, a 2-item screening tool, in morbidly obese patients and compare its performance with three other instruments: STOP-Bang questionnaire, NoSAS score, and Epworth Sleepiness Scale (ESS).

Methods: A cross-sectional analysis of morbidly obese patients (body mass index [BMI] ≥ 35. Read More

Medicine (Baltimore) 2019 Feb;98(6):e14405

Department of Neurology, Huashan Hospital Affiliated to Fudan University, Shanghai.

Rationale: Hypoglycemia, which is characterized mainly by palpitations, dizziness, and sweating, is common and easy to identify. However, some other symptoms, such as mental disorder or abnormal behavior, are atypical, which may lead to a misdiagnosis of epilepsy, sleepwalking, infarction, or mental disorder, among others.

Patient Concerns: We report a case of a patient with type 2 diabetes who presented with abnormal nocturnal behavior due to hypoglycemia. Read More

Sleep Breath 2019 Feb 7. Epub 2019 Feb 7.

Interdisciplinary Sleep Medicine Center, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Objectives: To determine if recording of suprasternal pressure (SSP) can classify apneas and hypopneas as reliably as respiratory inductance plethysmography (RIP) belts and to compare the two methods to classification with esophageal pressure (Pes), the reference method for assessing respiratory effort.

Methods: In addition to polysomnographic recordings that included Pes, SSP was recorded. Recordings from 32 patients (25 males, mean age 66. Read More

J Bras Pneumol 2018 Nov-Dec;44(6):510-518

. Laboratório do Sono, Disciplina de Pneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.

Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. Read More

J Sleep Res 2019 Feb 6:e12828. Epub 2019 Feb 6.

Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Obstructive sleep apnea (OSA) is associated with an increased risk of cardiovascular disease. Previous studies have assessed the relationship between OSA and coronary artery disease (CAD) using coronary artery calcium score (CAC) measurements. However, limited data are available regarding the association of OSA with non-calcified plaque burden. Read More

J Sleep Res 2019 Feb 6:e12821. Epub 2019 Feb 6.

Section of Neurology, Department of Clinical and Experimental Medicine, University of Pisa and Pisa University Hospital, Pisa, Italy.

The main condition at increased risk of dementia is considered to be mild cognitive impairment. Mild cognitive impairment has been defined as a transitional state between normal aging and dementia, of which it may represent a prodrome. The aim of our study was to evaluate whether sleep variables (both conventional and microstructural ones) in subjects with mild cognitive impairment correlate with conversion to dementia. Read More

Sleep 2019 Feb 5. Epub 2019 Feb 5.

National Reference Network for Narcolepsy, Department of Neurology, Hôpital Gui-de-Chauliac, CHU Montpellier, France.

Objective: The association between restless legs syndrome (RLS), periodic leg movements during sleep (PLMS) and iron deficiency has been reported in children with attention deficit/hyperactivity disorder (ADHD); however little is known in adults. The aim of this study was to assess frequencies of RLS, PLMS and other leg movements (LM) and iron deficiency and their relationships with ADHD phenotype in adults with ADHD.

Methods: 200 adults with ADHD (112 males, median age 31 years) were evaluated on lifetime ADHD symptoms and sleep characteristics. Read More

High Alt Med Biol 2019 Feb 5. Epub 2019 Feb 5.

Center for Heart, Lung and Vascular Health, University of British Columbia, Okanagan, Kelowna, Canada.

Patrician, Alexander, Michael M. Tymko, Hannah G. Caldwell, Connor A. Read More

Basic Clin Neurosci 2018 Nov-Dec;9(6):397-407. Epub 2018 Nov 1.

Sleep Disorders Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Introduction: There are controversial reports about association between sleep and Hypothalamic-Pituitary-Adrenal (HPA) activity. Studies have reported the influence of insomnia on HPA hormones. However, they usually ignored the heterogeneity of insomnia symptoms, so subtypes of the disorder have not been considered in the reports. Read More

Sleep Med 2019 Jan 5. Epub 2019 Jan 5.

INSERM, UMR1153, Center for Research in Epidemiology and StatisticS (CRESS), EArly life Research on later Health Team (EARoH), Univ Paris-Descartes, Paris, France.

Background: Few studies on the relationship between sleep quantity and/or quality and cognition have been conducted among preschoolers from the healthy general population. We aimed to identify, among 3-year-old children, early polysomnography (PSG) sleep factors associated with estimated intelligence quotient (IQ) using the Weschler Preschool and Primary Scale Intelligence-III test (WPPSI-III) and its indicators: full-scale (FISQ), verbal (VIQ), and performance (PIQ) intelligence quotients.

Methods: We included full-term children from the French birth-cohort AuBE with PSG recording at term (M0) and/or six months (M6), and available WPPSI-III scores at three years. Read More

IEEE Trans Neural Syst Rehabil Eng 2019 Jan 31. Epub 2019 Jan 31.

Automatic sleep staging has been often treated as a simple classification problem that aims at determining the label of individual target polysomnography (PSG) epochs one at a time. In this work, we tackle the task as a sequence-to-sequence classification problem that receives a sequence of multiple epochs as input and classifies all of their labels at once. For this purpose, we propose a hierarchical recurrent neural network named SeqSleepNet1. Read More