23,420 results match your criteria Polysomnography


ADHD symptoms are associated with decreased activity of fast sleep spindles and poorer procedural overnight learning during adolescence.

Neurobiol Learn Mem 2018 Dec 12. Epub 2018 Dec 12.

Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.

ADHD and its subclinical symptoms have been associated with both disturbed sleep and weakened overnight memory consolidation. As sleep spindle activity during NREM sleep plays a key role in both sleep maintenance and memory consolidation, we examined the association between subclinical ADHD symptoms and sleep spindle activity. Furthermore, we hypothesized that sleep spindle activity mediates the effect of ADHD symptoms on overnight learning outcome in a procedural memory task. Read More

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December 2018

Higher sleep spindle activity is associated with fewer false memories in adolescent girls.

Neurobiol Learn Mem 2018 Dec 12. Epub 2018 Dec 12.

Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Background: Sleep facilitates the extraction of semantic regularities amongst newly encoded memories, which may also lead to increased false memories. We investigated sleep stage proportions and sleep spindles in the recollection of adolescents' false memories, and their potential sex-specific differences.

Methods: 196 adolescents (mean age 16. Read More

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December 2018

Severity of obstructive sleep apnea and extension of coronary artery disease.

Sleep Breath 2018 Dec 14. Epub 2018 Dec 14.

School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Purpose: Obstructive sleep apnea (OSA) is highly prevalent among patients with coronary artery disease (CAD). The relationship between the severity of OSA and the severity of CAD has not been entirely established. The objective was to explore the type of correlation existent between the apnea-hypopnea index and the Gensini score, which provides granularity in terms of CAD extension and severity, in search of a dose-response relationship. Read More

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December 2018
1 Read

Sleep-disordered breathing among patients admitted for inpatient video-EEG monitoring.

Neurology 2018 Dec 14. Epub 2018 Dec 14.

From the Departments of Medicine (S.S., Z.C., A.P., C.J.R., N.C.J., C.F., P.P., P.K., T.J.O.), Neurology (S.S., E.J.W., A.P., C.H., J.C., C.J.R., R.Y., C.F., P.P., P.K., T.J.O.), and Respiratory and Sleep Disorders Medicine (T.M., J.G.), The Royal Melbourne Hospital, The University of Melbourne, Parkville; Department of Neuroscience (S.S., Z.C., A.P., N.C.J., C.F., P.P., P.K., T.J.O.), Central Clinical School, Monash University; Department of Neurology (S.S., A.P., P.P., P.K., T.J.O.), The Alfred Hospital; and Neuropsychiatry Unit (S.F., D.V.), The Royal Melbourne Hospital and Melbourne Neuropsychiatry Centre, Australia.

Objective: To examine the prevalence and risk factors of sleep-disordered breathing (SDB) in individuals with epilepsy and psychogenic nonepileptic seizures (PNES).

Methods: We conducted a cross-sectional study of consecutive patients admitted for inpatient video-EEG monitoring at The Royal Melbourne Hospital, Australia, between December 1, 2011, and July 31, 2017. Participants underwent routine clinical investigations during their monitoring period including polysomnography, neurocognitive testing, and screening instruments of daytime somnolence, sleep quality, and quality of life. Read More

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December 2018

Prevalence and associated risk factors of periodic limb movement in sleep in two German population-based studies.

Sleep 2018 Dec 14. Epub 2018 Dec 14.

Institute of Epidemiology and Social Medicine, Westfälische Wilhelms-Universität Münster, Münster, Germany.

Study Objectives: Periodic limb movements in sleep (PLMS) are frequent motor phenomena; however, population-based data are scarce. We assessed the prevalence of PLMS and factors associated with PLMS within two German population-based cohorts, the SHIP-TREND and BiDirect.

Methods: Single-night polysomnography was performed on 1107 subjects recruited from the general population (mean age: 52. Read More

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December 2018
1 Read

[Effects of sleep body posture on subjective sleepiness in patients with OSAHS].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1418-1421

Department of Otorhinolaryngology,the Affiliated Huaian No.1 People's Hospital of Nanjing Medical University,Huaian, 223300, China.

To observe the effects of sleep body posture on subjective sleepiness in patients with OSAHS. We assessed the sleeping body position, the sleep structure, position specific AHI and the Epworth Sleepiness Scale (ESS) in a total of 90 patients with OSAHS. The patients were grouped according to AHI: mild OSAHS (5≤AHI<15), moderate (15≤AHI<30) and severe (AHI≥30). Read More

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September 2018

[Relationship between upper airway volume and polysomnography parameters of patients with obstructive sleep apnea hypopnea syndrome].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1409-1413

Department of Otolaryngology, the University of Hong Kong-Shenzhen Hospital, Shenzhen, 518000, China.

To study the relationship among upper airway volume of naso-pharyngeal, yelo-pharyngeal,glosso-pharyngeal, hypo-pharyngeal area which measured by spiral computed tomography three-dimensional reconstruction technique, apnea hypopnea indexes, and the lowest oxygen saturation in patients with OSAHS.①fifty-one patients with OSAHS were received polysomnography, and then were divided into groups by the AHI,LSaO₂ values. ②To measure upper airway volume at normal breath and Müller maneuver state using spiral computed tomography three-dimensional reconstruction technique of CT measurement, and to calculate volume change rate and observe the upper airway compliance. Read More

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September 2018

[The application of cineMRI in evaluation of upper airway obstruction levels in complicated pediatric OSAS].

Authors:
S He R D Zhang J Chen

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1886-1889

Department of Otolaryngology, Shanghai Children's Medical Center Affiliated with Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China.

The aim of this study is to explore the role of cineMRI in the localization of upper airway obstruction in complicated pediatric OSAS. Eleven persistent OSAS and 11 complex OSAS patients underwent cineMRI. Each patient was imaged midline sagittal and axial magnetic resonance cine image. Read More

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December 2018

Inferring sleep stage from local field potentials recorded in the subthalamic nucleus of Parkinson's patients.

J Sleep Res 2018 Dec 13:e12806. Epub 2018 Dec 13.

Department of Physiology and Biophysics, University of Colorado School of Medicine, Aurora, Colorado.

Parkinson's disease (PD) is highly comorbid with sleep dysfunction. In contrast to motor symptoms, few therapeutic interventions exist to address sleep symptoms in PD. Subthalamic nucleus (STN) deep brain stimulation (DBS) treats advanced PD motor symptoms and may improve sleep architecture. Read More

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December 2018

Hypoglossal nerve stimulation in three adults with down syndrome and severe obstructive sleep apnea.

Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.

Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medicine, New York, New York.

We present three adults with Down syndrome and obstructive sleep apnea (OSA) treated with hypoglossal nerve stimulation. The average age of these three males was 37.3 years. Read More

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December 2018

Is obstructive sleep apnea syndrome related to nocturia?

Low Urin Tract Symptoms 2018 Dec 12. Epub 2018 Dec 12.

Department of Urology, Istanbul Taksim Gaziosmanpasa Training and Research Hospital, Istanbul, Turkey.

Objective: The aim of this study was to investigate the relationship between obstructive sleep apnea syndrome (OSAS) and lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH).

Methods: This multicenter study was performed on 122 male patients with dyspnea and/or sleep disorder. Patient characteristics were recorded. Read More

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December 2018
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The role of polysomnography in decannulation of children with brain and spinal cord injuries.

Pediatr Pulmonol 2018 Dec 11. Epub 2018 Dec 11.

Department of Pediatric Rehabilitation Medicine, Kennedy Krieger Institute, Baltimore, Maryland.

Objective: The objective of this retrospective review was to determine the utility of polysomnography (PSG) in influencing the decision to decannulate pediatric patients with brain and spinal cord injuries in an inpatient rehabilitation hospital setting.

Methods: Between 2010 and 2016, data were collected on pediatric patients with brain and/or spinal cord injuries who had PSG performed with the goal of decannulation. Patients underwent a decannulation protocol involving toleration of continuous tracheostomy capping and bedside tracheoscopy by otolaryngology. Read More

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December 2018

Fatigued Patients with Chronic Liver Disease Have Subtle Aberrations of Sleep, Melatonin and Cortisol Circadian Rhythms.

Fatigue 2018 3;6(1):5-19. Epub 2017 Dec 3.

Liver & Energy Metabolism Unit, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA.

Aims: We sought to examine whether disturbances in central and peripheral circadian rhythms were related to the experience of fatigue in patients with chronic liver disease (CLD).

Methods: Fatigued and non-fatigued patients with compensated CLD were enrolled in a prospective pilot study. Patients underwent a one week evaluation of free-living sleep and physical activity patterns, followed by a 24-hour admission, during which they underwent serial blood sampling, polysomnography, a 6-minute walk test and continuous core temperature measurements under standardized conditions. Read More

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December 2017
1 Read

Altered overnight levels of pro-inflammatory cytokines in men and women with posttraumatic stress disorder.

Psychoneuroendocrinology 2018 Dec 5;102:114-120. Epub 2018 Dec 5.

San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA; Department of Psychiatry, University of California, San Francisco, CA, USA; Northern California Institute for Research and Education, San Francisco, CA, USA.

Background: Posttraumatic stress disorder (PTSD) is associated with disturbed sleep and elevated levels of pro-inflammatory cytokines, including interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α). Studies in animals and healthy humans have also shown that disrupted sleep elevates pro-inflammatory cytokines, including IL-6 and TNF-α. A better understanding of overnight cytokine levels and sleep might shed light on possible mechanisms for elevated inflammation in PTSD. Read More

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December 2018

Monitoring the sleep patterns of people with dementia and their family carers in the community.

Australas J Ageing 2018 Dec 7. Epub 2018 Dec 7.

Sleep/Wake Research Centre, Massey University, Wellington, New Zealand.

Objectives: Gold-standard overnight polysomnography does not reliably capture highly variable sleep patterns across the 24-hour day that are common with dementia and often problematic for carers. We evaluated the reliability of automatically scored actigraphy data as an alternative.

Methods: Actigraphy recordings were analysed from 15 community-dwelling people with dementia (135 days total) and 14 of their family carers (124 days total). Read More

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December 2018

Increased Level of Angiopoietin Like Proteins 4 and 8 in People With Sleep Apnea.

Front Endocrinol (Lausanne) 2018 13;9:651. Epub 2018 Nov 13.

Biochemistry and Molecular Biology Unit, Dasman Diabetes Institute, Kuwait City, Kuwait.

Obstructive sleep apnea (OSA) is a sleep disorder caused by the complete or partial obstruction of the upper airways. The worldwide prevalence of OSA is increasing due to its close association with obesity epidemic and multiple health complications, such as hypertension, cardiovascular disease, and Type 2 diabetes. Angiopoietin-like protein (ANGPTL)-4 and ANGPTL8 (betatrophin) have been suggested to play a role in the development of these diseases through their role in regulating the metabolism of plasma lipid molecules. Read More

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November 2018
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Time domain characterization for sleep apnea in oronasal airflow signal: a dynamic threshold classification approach.

Physiol Meas 2018 Nov 28. Epub 2018 Nov 28.

Cardiology, SleepMedicine, Charite Universitaetsmedizin Berlin, Chariteplatz 1, D-10117 Berlin, Berlin, GERMANY.

Objective: Apneas are the most common type of sleep-related breathing disorders; they cause patients to move from restorative sleep into inefficient sleep. The American Academy of Sleep Medicine (AASM) considers sleep apnea as a hidden health crisis that affects 29.4 million adults costing USA billions of Dollars. Read More

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November 2018

Portable multi-parameter electrical impedance tomography (EIT) for sleep apnea and hypoventilation monitoring: feasibility study.

Physiol Meas 2018 Nov 20. Epub 2018 Nov 20.

Department of Biomedical Engineering, Kyung Hee University, Seoul, KOREA, REPUBLIC OF.

Quantitative ventilation monitoring and respiratory event detection are needed for the diagnosis of sleep apnea and hypoventilation. We report the development of a portable device with a chest belt, nasal cannula and finger sensor to continuously acquire multi-channel signals including tidal volume, nasal pressure, respiratory effort, body position, snoring sound, ECG and SpO2. The unique feature of the device is the continuous tidal volume signal obtained from real-time lung ventilation images produced by the electrical impedance tomography (EIT) technique. Read More

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November 2018

The impact of continuous positive airway pressure treatment on the recurrence of atrial fibrillation post cardioversion: A randomized controlled trial.

Int J Cardiol 2018 Nov 20. Epub 2018 Nov 20.

Department of Cardiovascular Diseases, Rochester, MN, USA.

Background: Observational data suggest that positive airway pressure (PAP) treatment of obstructive sleep apnea (OSA) can reduce the risk of recurrent atrial fibrillation (AF) post-direct current cardioversion (DCCV) or catheter ablation.

Methods: We conducted a study of adult patients with AF and sleep apnea, stratified by age and gender, who underwent successful DCCV to sinus rhythm, and who were randomized to receive PAP or usual care. Those with sleepiness, significant cardiac or respiratory disease were excluded. Read More

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November 2018

Predictors of CPAP adherence following stroke and transient ischemic attack.

Sleep Med 2018 Oct 24. Epub 2018 Oct 24.

Department of Medicine, Division of Neurology, University of Toronto, Canada; Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, Toronto, Canada; L.C. Campbell Cognitive Neurology Research Unit, Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Sunnybrook Health Sciences Centre, Toronto, Canada; Sleep Laboratory, Sunnybrook Health Sciences Centre, Toronto, Canada. Electronic address:

Objective: Continuous positive airway pressure (CPAP) has been shown to improve functional, motor and cognitive outcomes in post-stroke obstructive sleep apnea (OSA). However, rates of CPAP adherence are often low and factors impacting CPAP adherence remain under-explored. Our objective was to determine predictors of CPAP adherence in patients who had a stroke or transient ischemic attack (TIA). Read More

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October 2018

A novel adhesive biosensor system for detecting respiration, cardiac, and limb movement signals during sleep: validation with polysomnography.

Nat Sci Sleep 2018 26;10:397-408. Epub 2018 Nov 26.

Neurology Department, Massachusetts General Hospital, Boston, MA 02114, USA.

Background: Although in-lab polysomnography (PSG) remains the gold standard for objective sleep monitoring, the use of at-home sensor systems has gained popularity in recent years. Two categories of monitoring, autonomic and limb movement physiology, are increasingly recognized as critical for sleep disorder phenotyping, yet at-home options remain limited outside of research protocols. The purpose of this study was to validate the BiostampRC sensor system for respiration, electrocardiography (ECG), and leg electromyography (EMG) against gold standard PSG recordings. Read More

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November 2018

Positive airway pressure for sleep-disordered breathing in acute quadriplegia: a randomised controlled trial.

Thorax 2018 Dec 11. Epub 2018 Dec 11.

Department of Respiratory and Sleep Medicine, Royal North Shore Hospital, St Leonards, New South Wales, Australia.

Rationale: Highly prevalent and severe sleep-disordered breathing caused by acute cervical spinal cord injury (quadriplegia) is associated with neurocognitive dysfunction and sleepiness and is likely to impair rehabilitation.

Objective: To determine whether 3 months of autotitrating CPAP would improve neurocognitive function, sleepiness, quality of life, anxiety and depression more than usual care in acute quadriplegia.

Methods And Measurements: Multinational, randomised controlled trial (11 centres) from July 2009 to October 2015. Read More

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December 2018

Neural network analysis of sleep stages enables efficient diagnosis of narcolepsy.

Nat Commun 2018 12 6;9(1):5229. Epub 2018 Dec 6.

Center for Sleep Science and Medicine, Stanford University, Stanford, 94304, CA, USA.

Analysis of sleep for the diagnosis of sleep disorders such as Type-1 Narcolepsy (T1N) currently requires visual inspection of polysomnography records by trained scoring technicians. Here, we used neural networks in approximately 3,000 normal and abnormal sleep recordings to automate sleep stage scoring, producing a hypnodensity graph-a probability distribution conveying more information than classical hypnograms. Accuracy of sleep stage scoring was validated in 70 subjects assessed by six scorers. Read More

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December 2018

Gene Expression Profiles of Tumor Necrosis Factor-α and Endothelin-1 in Obstructive Sleep Apnea.

ORL J Otorhinolaryngol Relat Spec 2018 Dec 11;81(1):16-23. Epub 2018 Dec 11.

Department of Otolaryngology and Head and Neck Surgery, Wakayama University Hospital, Wakayama, Japan.

Background/aims: The aim of this study was to observe the relationship between the gene expression profiles of tumor necrosis factor (TNF)-α and endothelin (EDN)-1 and obstructive sleep apnea (OSA).

Methods: A prospective, cross-sectional study performed at a tertiary-care academic center; 108 patients with snoring and day-time sleeplessness were included in this study carried out in the Otolaryngology Department. All patients were evaluated with 1-night polysomnography (PSG). Read More

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December 2018
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Sleep EEG Derived From Behind-the-Ear Electrodes (cEEGrid) Compared to Standard Polysomnography: A Proof of Concept Study.

Front Hum Neurosci 2018 26;12:452. Epub 2018 Nov 26.

Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom.

Electroencephalography (EEG) recordings represent a vital component of the assessment of sleep physiology, but the methodology presently used is costly, intrusive to participants, and laborious in application. There is a recognized need to develop more easily applicable yet reliable EEG systems that allow unobtrusive long-term recording of sleep-wake EEG ideally away from the laboratory setting. cEEGrid is a recently developed flex-printed around-the-ear electrode array, which holds great potential for sleep-wake monitoring research. Read More

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November 2018

Wavelet analysis of oximetry recordings to assist in the automated detection of moderate-to-severe pediatric sleep apnea-hypopnea syndrome.

PLoS One 2018 7;13(12):e0208502. Epub 2018 Dec 7.

Biomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain.

Background: The gold standard for pediatric sleep apnea hypopnea syndrome (SAHS) is overnight polysomnography, which has several limitations. Thus, simplified diagnosis techniques become necessary.

Objective: The aim of this study is twofold: (i) to analyze the blood oxygen saturation (SpO2) signal from nocturnal oximetry by means of features from the wavelet transform in order to characterize pediatric SAHS; (ii) to evaluate the usefulness of the extracted features to assist in the detection of pediatric SAHS. Read More

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December 2018

A phenotype of increased sleepiness in a mouse model of pulmonary hypertension and right ventricular hypertrophy.

PLoS One 2018 7;13(12):e0208540. Epub 2018 Dec 7.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.

The relationship between cardiovascular disease and abnormalities in sleep architecture is complex and bi-directional. Sleep disordered breathing (SDB) often confounds human studies examining sleep in the setting of heart failure, and the independent impact of isolated right or left heart failure on sleep is difficult to assess. We utilized an animal model of right heart failure using pulmonary artery banding (PAB) in mice to examine the causal effect of right heart failure on sleep architecture. Read More

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December 2018

Automated Sleep Apnea Detection in Raw Respiratory Signals using Long Short-Term Memory Neural Networks.

IEEE J Biomed Health Inform 2018 Dec 10. Epub 2018 Dec 10.

Sleep apnea is one of the most common sleep disorders and the consequences of undiagnosed sleep apnea can be very severe, ranging from increased blood pressure to heart failure. However, many people are often unaware of their condition. The gold standard for diagnosing sleep apnea is an overnight polysomnography in a dedicated sleep laboratory. Read More

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December 2018

Accuracy of the sleep-related breathing disorder scale to diagnose obstructive sleep apnea in children: a meta-analysis.

Sleep Med 2018 Oct 28;54:78-85. Epub 2018 Oct 28.

Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France; Paris Diderot University, 10 Avenue de Verdun, 75010, Paris, France; DHU PROTECT, INSERM U1141, Robert Debre University Hospital, Paris, France. Electronic address:

Objectives: The main objective of this meta-analysis was to assess the accuracy of the Sleep-Related Breathing Disorder (SRBD) Scale in the diagnosis of obstructive sleep apnea syndrome (OSAS) in children.

Patients/methods: A literature search of studies comparing SRBD to polysomnography for the diagnosis of OSAS in children was performed. Risks of biases were quantified using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool. Read More

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October 2018

Obstructive sleep apnea as a predictor of reduced heart rate variability.

Sleep Med 2018 Oct 11;54:8-15. Epub 2018 Oct 11.

Department of Internal Medicine, Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, Borowska 213, PL 50-556, Wroclaw, Poland.

Purpose: This study aimed to analyze the relationship between the occurrence of obstructive sleep apnea (OSA) and heart rate variability (HRV) in a group of patients with clinical suggestion of OSA.

Methods: 104 patients with clinical suspicion of OSA were qualified to participate in the study (age: 53.15 ± 13. Read More

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October 2018
2 Reads

Quantitative analysis of carotid arterial calcification using airway CT in obstructive sleep apnea.

Auris Nasus Larynx 2018 Dec 6. Epub 2018 Dec 6.

Department of Otorhinolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Republic of Korea.

Objective: To evaluate the relationship between obstructive sleep apnea (OSA) severity and carotid arterial calcification by quantitative analysis using airway computed tomography (CT).

Methods: This study included a total of 180 consecutive OSA patients aged 45-80years underwent polysomnography and airway CT between March 2014 and October 2016. The subjects were divided into three groups based on the results of the respiratory disturbance index (RDI): mild (RDI 5-14, n=29), moderate (RDI 15-29, n=50), and severe (RDI≥30, n=101). Read More

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December 2018
2 Reads

Clinical Use of a Home Sleep Apnea Test: An Updated American Academy of Sleep Medicine Position Statement.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Abstract: The diagnosis and effective treatment of obstructive sleep apnea (OSA) in adults is an urgent health priority. It is the position of the American Academy of Sleep Medicine (AASM) that only a medical provider can diagnose medical conditions such as OSA and primary snoring. Throughout this statement, the term "medical provider" refers to a licensed physician and any other health care professional who is licensed to practice medicine in accordance with state licensing laws and regulations. Read More

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November 2018
1 Read
3.053 Impact Factor

The Value of a Well-Trained Ear: Incidental Detection of Catathrenia on Home Sleep Apnea Tests in Patients With Low Probability for Obstructive Sleep Apnea.

Authors:
Louis Kazaglis

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Abstract: Catathrenia is a rare sleep-related breathing disorder marked by nocturnal groaning during prolonged exhalation. Home sleep apnea tests are growing in popularity, but no prior case reports exist documenting catathrenia detected by a home sleep apnea test. We report two cases of catathrenia incidentally detected in patients with low to intermediate risk of obstructive sleep apnea, in which diagnostic polysomnography was recommended but denied by insurers. Read More

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November 2018
1 Read

Practical Implementation of a Single-Night Split-Titration Protocol With BPAP-ST and AVAPS in Patients With Neuromuscular Disease.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Study Objectives: At the sleep laboratory, noninvasive positive pressure ventilation titration protocols in patients with neuromuscular disease (NMD) are based on standard pressure cycle devices in a spontaneous/timed mode (BPAP-ST). Experience integrating protocols on average volume-assured pressure support (AVAPS) mode is limited, prompting us to develop a practical single-night titration protocol that provides information to assist clinicians and patients as they decide between BPAP-ST and AVAPS modes.

Methods: We implemented a sequential titration protocol of BPAP-ST followed by AVAPS during a single-night polysomnography study in patients with NMD and reported polysomnographic and clinical metrics. Read More

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November 2018
1 Read
3.053 Impact Factor

Oximetry as an Accurate Tool for Identifying Moderate to Severe Sleep Apnea in Patients With Acute Stroke.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Study Objectives: Sleep-disordered breathing (SDB) is highly prevalent in patients with acute stroke. SDB is often underdiagnosed and associated with neurological deterioration and stroke recurrence. Polysomnography or home sleep apnea testing (HSAT) is typically used as the diagnostic modality; however, it may not be feasible to use regularly in patients with acute stroke. Read More

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November 2018
1 Read

Varying Hypopnea Definitions Affect Obstructive Sleep Apnea Severity Classification and Association With Cardiovascular Disease.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Study Objectives: To compare clinical features and cardiovascular risks in patients with obstructive sleep apnea (OSA) based on ≥ 3% desaturation or arousal, and ≥ 4% desaturation hypopnea criteria.

Methods: This is a cross-sectional analysis of 1,400 veterans who underwent polysomnography for suspected sleep-disordered breathing. Hypopneas were scored using ≥ 4% desaturation criteria per the American Academy of Sleep Medicine (AASM) 2007 guidelines, then re-scored using ≥ 3% desaturation or arousal criteria per AASM 2012 guidelines. Read More

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November 2018
1 Read

The Accuracy of an Ambulatory Level III Sleep Study Compared to a Level I Sleep Study for the Diagnosis of Sleep-Disordered Breathing in Children With Neuromuscular Disease.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Study Objectives: Polysomnography (PSG) surveillance recommendations are not being met for children with neuromuscular disease (NMD) because of limited diagnostic facilities. We evaluated the diagnostic accuracy of an ambulatory level III device as compared to a level I PSG.

Methods: A cross-sectional study was conducted at a tertiary pediatric institution. Read More

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November 2018
2 Reads

Long Sleep Duration, Insomnia, and Insomnia With Short Objective Sleep Duration Are Independently Associated With Short Telomere Length.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Study Objectives: We aimed to determine the association between short telomere length, sleep parameters, and sleep disorders in an adult general population sample.

Methods: As part of the EPISONO cohort (São Paulo, Brazil), 925 individuals answered questionnaires, underwent a full-night polysomnography and clinical assessment, and had peripheral blood collected for DNA extraction. Insomnia was diagnosed based on the Diagnostic and Statistical Manual of Mental Disorders, 4th edition; and obstructive sleep apnea was defined according to apnea-hypopnea index. Read More

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November 2018
1 Read

Objectively Measured Disrupted Sleep Is Independently and Directly Associated With Low Exercise Capacity in Males: A Structural Equation Model.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Study Objectives: We investigated the interaction between objective sleep disturbance and obesity, sedentary lifestyle, and lung dysfunction and whether it is negatively associated with cardiorespiratory fitness.

Methods: In this community cohort study of 521 men (age 46.6 ± 7. Read More

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November 2018
1 Read

Potential Anatomic Markers of Obstructive Sleep Apnea in Prepubertal Children.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Study Objectives: Adenotonsillar hypertrophy is the major cause of obstructive sleep apnea (OSA) in prepubertal children, but children without enlarged lymphoid tissues may still suffer from OSA. This study aimed to identify other potential anatomic features associated with childhood OSA.

Methods: This prospective study took place between January 2010 and April 2014. Read More

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November 2018
4 Reads

Objective sleep alterations and long-term use of short or intermediate half-life benzodiazepine receptor agonists are risk factors for high blood pressure in individuals with insomnia: a study in 1272 individuals referred for sleep examinations.

Sleep Med 2018 Oct 4;53:115-123. Epub 2018 Oct 4.

Erasme Hospital, Department of Psychiatry and Sleep Laboratory, Université Libre de Bruxelles, ULB, Brussels, Belgium.

Introduction: Given conflicting data in the literature, the aim of this study was to examine the risk of high blood pressure (HBP) associated with sleep alterations, measured during polysomnography, and long-term use of benzodiazepine receptor agonists in a large sample of individuals with insomnia.

Methods: Demographic and polysomnographic data from 1272 individuals with insomnia recruited from the research database of the sleep laboratory of Erasme Hospital were analyzed. HBP status was defined by the presence of one of the following: self-report at interview of either a physician's diagnosis or taking antihypertensive medication; or an average systolic blood pressure ≥140 mm Hg or an average diastolic blood pressure ≥90 mm Hg at the medical examination. Read More

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October 2018
1 Read

Measurement and Nonpharmacologic Management of Sleep Disturbance in the Intensive Care Units: A Literature Review.

Crit Care Nurs Q 2019 Jan/Mar;42(1):75-80

Princess Aisha Bint Al-Hussein College of Nursing & Health Sciences, Al-Hussein Bin Talal University, Maan, Jordan (Dr Bani Younis); Faculty of Nursing, University of Jordan, Amman, Jordan (Dr Hayajneh); and Philadelphia University, Amman, Jordan (Dr Batiha).

The general goal of this review is to summarize, clarify, and evaluate what is known about patients' sleep in the intensive care units (ICUs) in terms of sleep measurement and management. In addition, this review focuses on the gap in knowledge in this field. A review of online databases for relevant articles in the period between 2000 and 2017 was conducted. Read More

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December 2018
1 Read

Obstructive sleep apnea in patients with chronic thromboembolic pulmonary hypertension.

J Thorac Dis 2018 Oct;10(10):5804-5812

Center for Pulmonary Vascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

Background: Due to its effects, like an exaggerated negative intrathoracic pressure, sympathetic activation, systemic inflammation, oxidative stress, and endothelial dysfunction, obstructive sleep apnea (OSA) has been involved as a cause in multiple cardiovascular diseases. These diseases include coronary artery disease, hypertension, heart failure, and pulmonary hypertension (PH). Furthermore, OSA often coexists with chronic thromboembolic pulmonary hypertension (CTEPH) in clinical practice. Read More

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October 2018
1 Read

Atrial Fibrillation and Objective Sleep Quality by Slow Wave Sleep.

J Atr Fibrillation 2018 Aug 31;11(2):2031. Epub 2018 Aug 31.

Cardiovascular Division, Department of Medicine, University of Virginia.

Background: Self-reported poor sleep quality has been suggested in patients with AF. Slow wave sleep (SWS) is considered the most restorative sleep stage and represents an important objective measure of sleep quality. The aim of this study was to compare quantity of SWS between patients with and without AF. Read More

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August 2018
6 Reads

A Pilot Randomized-Controlled Trial on the Effect of CPAP Treatment on Glycemic Control in Gestational Diabetes: Study Design and Methods.

Front Endocrinol (Lausanne) 2018 16;9:659. Epub 2018 Nov 16.

Division of Respiratory Medicine, Department of Medicine, McGill University Health Centre, McGill University, Montreal, QC, Canada.

Gestational diabetes (GDM) is associated with adverse short- and long-term maternal and fetal outcomes. Observational data support a link between sleep-disordered breathing (SDB) during pregnancy and GDM. However, it is unknown whether treatment of SDB with continuous positive airway pressure (CPAP) improves glucose control in this patient population. Read More

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November 2018
1 Read

Sleep and breathing disturbances in patients with chronic obstructive pulmonary disease traveling to altitude: a randomized trial.

Sleep 2018 Dec 4. Epub 2018 Dec 4.

Department of Respiratory Medicine, Sleep Disorders Center, University Hospital Zurich, Zurich, Switzerland and Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.

Study Objectives: Patients with chronic obstructive pulmonary disease (COPD) have impaired pulmonary gas exchange near sea level. The purpose of the current study was to investigate whether exposure to hypobaric hypoxia during a stay at altitude affects nocturnal oxygen saturation, breathing pattern, and sleep in patients with moderate to severe COPD.

Methods: Thirty-two patients with COPD, median age 67 years, FEV1 59% predicted, PaO2 68 mmHg, living below 800 m, underwent polysomnography and questionnaire evaluations in Zurich (490 m), and in Swiss Alpine villages at 1650 and 2590 m, for two nights each, in random order. Read More

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December 2018
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SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR CONCENTRATION DECREASES IN CORRELATION WITH GLYCATED HEMOGLOBIN LEVELS IN PATIENTS WITH TYPE 2 DIABETES.

Georgian Med News 2018 Oct(283):55-58

Davit Tvildiani Medical University; Diabetes, Endocrine and Cardio-pulmonary Disease Center "Diacor"; P. Sarajishvili Institute of Neurolog, Tbilisi, Georgia.

Our aim was to compare serum vascular endothelial growth factor (VEGF) level in type 2 diabetes mellitus (T2DM) patients with comorbid OSA at screening and 6 month follow up visits. In the prospective cohort study following data were collected at screening visit: medical anamnesis; demographic and anthropometric data; Epworth sleepiness score data; laboratory (serum VEGF, complete blood count, biochemistry, immunology, complete urine test, including microalbuminuria) and instrumental investigation data (fundoscophy, laboratory polysomnography). At 6 months follow up visit we evaluated anthropometric data; Epworth sleepiness score; serum VEGF. Read More

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October 2018
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CONNECTION BETWEEN SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVELS AND SEVERITY OF MICROANGIOPATHY IN PATIENTS WITH TYPE 2 DIABETES AND OBSTRUCTIVE SLEEP APNEA.

Georgian Med News 2018 Oct(283):51-54

Davit Tvildiani Medical University; Diabetes, Endocrine and Cardio-pulmonary Disease Center "Diacor"; P. Sarajishvili Institute of Neurology, Tbilisi, Georgia.

Our aim was to evaluate the serum vascular endothelial growth factor (VEGF) level in type 2 diabetes patients with comorbid obstructive sleep apnea (OSA) and to compare it in connection with diabetic retinopathy and chronic kidney disease severity. In the prospective cohort study following data were collected: medical anamnesis; demographic and anthropometric data; laboratory (serum VEGF, complete blood count, biochemistry, immunology, complete urine test, including microalbuminuria) and instrumental investigation data (fundoscophy, laboratory polysomnography). From 232 analyzed patients 54 (23. Read More

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October 2018
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Sleep Quality and Levodopa Intestinal Gel Infusion in Parkinson's Disease: A Pilot Study.

Parkinsons Dis 2018 1;2018:8691495. Epub 2018 Nov 1.

Movement Disorders Unit, Department of Neurology, Hospital Universitari Vall D'Hebron, Neurodegenerative Diseases Research Group-Vall D'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.

Background: Sleep problems in patients with advanced Parkinson's disease (PD) have a deleterious impact on quality of life.

Objective: To assess the effect of levodopa-carbidopa intestinal gel (LCIG) infusion on sleep quality in advanced PD patients.

Methods: Seven patients participated in a prospective pilot study. Read More

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November 2018
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Cross-Sectional and Longitudinal Associations Between Athlete Burnout, Insomnia, and Polysomnographic Indices in Young Elite Athletes.

J Sport Exerc Psychol 2018 Dec 5:1-13. Epub 2018 Dec 5.

1 University of Basel.

Few studies have examined the association between sleep and burnout symptoms in elite athletes. We recruited 257 young elite athletes (M = 16.8 years) from Swiss Olympic partner schools. Read More

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December 2018
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