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Indian Dermatol Online J 2021 Mar-Apr;12(2):211-219. Epub 2021 Mar 2.

Department of Dermatology, Venereology and Leprosy, Pondicherry Institute of Medical Sciences, Pondicherry, India.

Polymorphous light eruption (PMLE) is the most common, idiopathic, acquired photodermatosis, characterized by abnormal, recurrent, and delayed reaction to sunlight. Polymorphous light eruption is common worldwide but the morphology, distribution, and pigmentary changes are unique in Indian skin which is discussed in this review. The prevalence of PMLE is around 10-20% in the general population. Read More

JAAD Case Rep 2021 Jan 1;7:17-19. Epub 2020 Nov 1.

Department of Dermatology and Venereology, Soroka University Medical Center, Beer-Sheva, Israel.

Dermatol Ther 2020 11 10;33(6):e14342. Epub 2020 Oct 10.

Department of Dermatology and Venereology, Cerrahpaşa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Erythroderma, or exfoliative dermatitis, is an inflammatory disorder characterized by erythema and scaling, affecting most of the skin surface. It may be a result of many different causes such as previous dermatoses (psoriasis, eczema, atopic dermatitis [AD], pityriasis rubra pilaris, and pemphigus foliaceous), drug reactions, malignancies (mycosis fungoides [MF], Sézary syndrome, adult T cell leukemia/lymphoma), infections, and idiopathic disorders. Regardless of the etiology, the clinical appearance of erythroderma is similar in all patients. Read More

Photodermatol Photoimmunol Photomed 2020 Sep 11;36(5):396-397. Epub 2020 May 11.

Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA.

Photodermatol Photoimmunol Photomed 2020 May 12;36(3):233-240. Epub 2020 Mar 12.

Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.

Background: Previous studies at single academic institutions have identified variations in the prevalence of photodermatoses among racial groups. The purpose of the study was to compare the distribution of photodermatoses between Whites and Blacks at four academic medical centers in the USA.

Methods: A retrospective chart review was performed at four institutions' general dermatology clinics using diagnoses consistent with the International Classification of Disease (ICD), Ninth and Tenth Revisions, codes related to photodermatoses between August 2006 and August 2016. Read More

Pan Afr Med J 2019 6;34:12. Epub 2019 Sep 6.

Service de Dermatologie-Vénérologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc.

Polymorphic lucite (PL) is a frequent photodermatosis, but its pathophysiologic mechanism is still poorly elucidated. We report the case of a 54-year old male teacher, with no previous medical-surgical history, presenting with recurrent papular and very pruritic rash lasting for 12 years. Clinical examination showed papular-vesicular excoriated lesions on the face, the neck and the scalp. Read More

Mater Sci Eng C Mater Biol Appl 2020 Feb 14;107:110254. Epub 2019 Oct 14.

Key Laboratory of Biorheological Science and Technology, Ministry of Education, Bioengineering College, Chongqing University, Chongqing, 400044, China; Department of Dermatology, Chongqing First People's Hospital and Chongqing Traditional Chinese Medicine Hospital, Chongqing, 400011, China. Electronic address:

Polymorphous light eruption (PLE) is one of the acquired idiopathic photodermatosis mainly induced by immoderate UV radiation. In order to realize UV protection and medicine administration simultaneously for polymorphous light eruption protection and therapy, Acetyl-11-keto-β-boswellic acid (AKBA) loaded Zinc Oxide (ZnO) nanoparticles of which drug release behavior is UV-controlled has been successfully synthesized. Such nanoparticles can not only reflect UV but also transfer the energy to release AKBA which presents an excellent antioxidant and anti-inflammatory effects. Read More

Dermatol Clin 2020 Jan 18;38(1):71-77. Epub 2019 Oct 18.

Department of Dermatology, Henry Ford Health System, 3031 West Grand Boulevard, Suite 800, Detroit, MI 48202, USA. Electronic address:

Ultraviolet light (UV) and visible light are important components in the diagnosis of photodermatoses, and UV has the unique ability to also be used to manage photodermatoses. Phototesting, provocative light testing, and photopatch testing can provide important information in diagnosing patients with photodermatoses; phototesting can be used to determine the starting dose for phototherapy in these patients. Once photosensitivity is established, narrowband UVB and UVA1 therapy have helped to improve the quality of life of photosensitive patients, such as those with polymorphous light eruption, chronic actinic dermatitis, and solar urticaria. Read More

Antioxidants (Basel) 2019 Jul 31;8(8). Epub 2019 Jul 31.

School of Medicine, University of Zagreb, Šalata 3, 10 000 Zagreb, Croatia.

Due to their potential health-promoting effects, carotenoids have drawn both scientific and public attention in recent years. The primary source of carotenoids in the human skin is diet, mainly fruits, vegetables, and marine product, but they may originate from supplementation and topical application, too. In the skin, they accumulate mostly in the epidermis and act as a protective barrier to various environmental influences. Read More

Indian J Dermatol Venereol Leprol 2019 Nov-Dec;85(6):597-604

Departments of Dermatology, All India Institute of Medical Sciences, New Delhi, India.

Background: Facial papules are a feature of several clinical conditions and may present both diagnostic and therapeutic challenges.

Aim: To describe a grouped papular eruption on the nose and adjoining cheeks that has not been well characterized previously.

Materials And Methods: A series of consecutive patients with a papular eruption predominantly involving nose and cheeks were evaluated, treated and followed up prospectively at tertiary care centers. Read More

Dtsch Arztebl Int 2018 09;115(38):627

J Dermatol 2019 05 10;46(5):e148-e149. Epub 2018 Oct 10.

Department of Dermatology, Kansai Medical University, Osaka, Japan.

Dermatology 2018;234(5-6):192-193. Epub 2018 Sep 10.

Clin Dermatol 2018 May - Jun;36(3):369-375. Epub 2018 Mar 21.

Department of Dermatology, SUNY Downstate Medical Center, Brooklyn, NY.

Topical sunscreens are the mainstay for protection from ultraviolet (UV) radiation. With skin cancer rates on the rise and great interest in reversing or preventing the effects of photoaging, new molecules with potential to defend against UV damage have received a great deal of attention. Specifically, there is a growing interest in herbal substances that offer protection against the damaging effects of UV rays. Read More

Adv Exp Med Biol 2017 ;996:111-122

Department of Dermatology and Venereology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Skin colour (specifically in relation to its melanin content and composition) has a marked influence on its interaction with ultraviolet light. Eumelanin has mainly photoprotective properties while pheomelanin has the ability to cause formation of reactive oxygen species. This difference is responsible for the difference in incidence and presentation of various idiopathic photodermatoses in dark skinned patients compared to those with lighter skin types. Read More

Adv Exp Med Biol 2017 ;996:61-70

University of Genoa, Genoa, Italy.

Polymorphous light eruption (PLE) is the commonest immuno-mediated photodermatosis. It occurs after solar or artificial UV-light exposure and affects only the sun-exposed areas with preference of the V-area of the chest, of arms and forearms, legs, upper part of the back, and rarely the face. The lesions are itching or burning, and vary morphologically from erythema to papules, vesico-papules and occasionally blisters, plaques, sometimes erythema multiforme-like, insect bite-like wheals and purpura. Read More

Am J Clin Dermatol 2018 Apr;19(2):223-235

Department of Dermatology, Hôpital Henri Mondor, 51 Avenue du Maréchal de Lattre de Tassigny, 94010, Créteil, France.

Vitamin D plays a key role in skeletal and cardiovascular disorders, cancers, central nervous system diseases, reproductive diseases, infections, and autoimmune and dermatological disorders. The two main sources of vitamin D are sun exposure and oral intake, including vitamin D supplementation and dietary intake. Multiple factors are linked to vitamin D status, such as Fitzpatrick skin type, sex, body mass index, physical activity, alcohol intake, and vitamin D receptor polymorphisms. Read More

Biotechnol Adv 2017 Nov 17;35(6):751-757. Epub 2017 Jul 17.

Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Institute of Dermatology & Venereology of Yunnan Province, Kunming, Yunnan, China. Electronic address:

Polymorphous light eruption (PLE) which is one of the most common photodermatoses has been demonstrated to be immune-mediated disorder. Resistance to UV-induced immunosuppression resulting from differential immune cells infiltration and cytokines secretion has been highlighted in the pathogenesis of PLE. In this study, we reviewed differential patterns of immune cells infiltrations and cytokines secretion that may contribute to PLE occurrence and development. Read More

Clin Exp Dermatol 2017 Aug 22;42(6):708-710. Epub 2017 May 22.

Department of Dermatology, Hospital del Mar-Parc de Salut Mar, Barcelona, Spain.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2017 Jun;60(6):605-617

Abteilung Allergologie, Paul-Ehrlich-Institut, Paul-Ehrlich-Str. 51-59, 63225, Langen, Deutschland.

Background: Multiple environmental exposures may derange the regulatory and repair mechanisms of the skin and lead to dermatological disease.

Objectives: Provide an overview of non-allergic skin diseases associated with environmental factors.

Materials And Methods: Review of current scientific evidence for associations of non-allergic skin diseases with environmental exposures: irritation, chemicals, infection, UV-radiation, temperature. Read More

Photodermatol Photoimmunol Photomed 2017 05 13;33(3):172-175. Epub 2017 Mar 13.

Department of Dermatology, Kansai Medical University, Osaka, Japan.

J Dermatol 2018 Jan 2;45(1):109-110. Epub 2017 Feb 2.

Department of Dermatology, Kansai Medical University, Hirakata, Japan.

Semin Diagn Pathol 2017 May 14;34(3):273-284. Epub 2016 Dec 14.

Section of Dermatopathology, Division of Surgical Pathology & Cytopathology, University of Virginia Medical Center, Room 3020 University of Virginia Hospital, 1215 Lee Street, Charlottesville, VA 22908-0214, USA. Electronic address:

Some cutaneous inflammatory disorders are typified by a predominant or exclusive localization in the dermis. They can be further subdivided by the principal cell types into lymphocytic, neutrophilic, and eosinophilic infiltrates, and mixtures of them are also seen in a proportion of cases. This review considers such conditions. Read More

Dermatol Online J 2016 Jun 15;22(6). Epub 2016 Jun 15.

UCSF Psoriasis and Skin Treatment Center.

Polymorphous light eruption (PMLE) is the most common photodermatosis characterized by pruritic papules and papulovesicles, which appear hours to days following ultraviolet (UV) exposure. Herein, the authors report successful treatment of generalized plaque psoriasis with Goeckerman regimen in a patient despite new onset iatrogenic PMLE following narrowband (NB) UVB therapy. Although further studies are necessary, this case suggests that the co-existence of psoriasis and PMLE should not prevent the use of phototherapy; phototherapy, especially as part of the Goeckerman regimen, remains a valuable treatment option for psoriasis in patients with PMLE. Read More

Eur J Dermatol 2016 Jun;26(3):304-6

Photobiology Unit, "Andreas Sygros" Hospital for Skin, Venereal Diseases, First Department of Dermatology, University of Athens Medical School, Greece - 5 I Dragoumi Str, 16121 Athens.

Wien Med Wochenschr 2016 May 13;166(7-8):250-3. Epub 2016 Jan 13.

Policlinic for Dermatology and Venereology, University Hospital Lozenetz, Koziak street 1, 1407, Sofia, Bulgaria.

Lupus tumidus is a rare immunological disorder whose pathogenesis is not fully understood. Although on the one hand there are some differences in (1) the clinical morphology of lesions, (2) the histopathology picture, as well as in (3) serological profile of lupus tumidus patients at the current moment, the disease is regarded as a subform of chronic cutaneous lupus erythematosus. Differential diagnosis requires the exclusion of many diseases such as Jessner Kanoff lymphocytic infiltration, polymorphous light eruption, and reticular erythematous mucinosis. Read More

Am J Dermatopathol 2015 Sep;37(9):721-3

*Department of Medicine, Division of Dermatology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY; †Department of Medicine, Division of Dermatology, Washington University School of Medicine, St. Louis, MO; ‡Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO; §Advanced Dermatology of Westchester, PLLC, Tarrytown, NY; ¶Dermpath Diagnostics, Port Chester, NY; and ‖Department of Pathology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.

Juvenile spring eruption (JSE) is a unique condition that typically affects the helices of the ears of boys and young men. The classical clinical picture of JSE includes the abrupt onset of lesions after spending time outdoors in the early spring. Because of the papulovesicular nature of the rash and the history of sun exposure, JSE is considered a variant of polymorphous light eruption. Read More