Altered expression of circadian clock genes in polyglandular autoimmune syndrome type III.
- Authors:
- Anna Angelousi,
- Narjes Nasiri-Ansari,
- Eliana Spilioti,
- Emilia Mantzou,
- Vasiliki Kalotyxou,
- George Chrousos,
- Gregory Kaltsas,
- Eva Kassi
Endocrine 2018 Jan 7;59(1):109-119. Epub 2017 Sep 7.
Department of Biological Chemistry, School of Medicine, National and Kapodistrian University of Athens, Athens, 11527, Greece.
Purpose: Circadian timing system is a highly conserved, ubiquitous molecular "clock" which creates internal circadian rhythmicity. Dysregulation of clock genes expression is associated with various diseases including immune dysregulation. In this study we investigated the circadian pattern of Clock-related genes in patients with polyglandular autoimmune syndrome type III (PAS type III). Read More