ILAR J 2017 Aug 28:1-14. Epub 2017 Aug 28.
Division of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon. Department of Obstetrics and Gynecology, Oregon Health & Sciences University, Portland, Oregon. Division of Reproductive Science in Medicine, Feinberg School of Medicine. Molecular Biosciences, Weinberg College of Arts and Sciences, Northwestern University in Chicago, Illinois.
The comparative biology of reproduction and development in mammalian species is remarkable. Hence, because of similarities in environmental and neuroendocrine control of the reproductive axis, the cyclic function of the ovary and reproductive tract, establishment and control of the maternal-fetal-placental unit during pregnancy, and reproductive aging from puberty through menopause, nonhuman primates (NHPs) are valuable models for research related to women's reproductive health and its disorders. This chapter provides examples of research over the past 10+ years using Old World monkeys (notably macaque species), baboons, and to a lesser extent New World monkeys (especially marmosets) that contributed to our understanding of the etiology and therapies or prevention of: (1) ovarian disorders, e. Read More