1,648 results match your criteria Polychondritis


A case of tracheobronchomalacia due to relapsing polychondritis treated with Montgomery T-tube.

SAGE Open Med Case Rep 2019 8;7:2050313X19832164. Epub 2019 Mar 8.

Department of Internal Medicine, Haeundae Paik Hospital, College of Medicine, Inje University, Busan, Republic of Korea.

Relapsing polychondritis is a rare and multi-system autoimmune disease of unknown etiology characterized by inflammation and destruction of cartilaginous structures. Its clinical manifestations include recurrent chondritis of the ears, nose, pinna, peripheral joints, and laryngotracheobronchial tree and can be life-threatening in advanced cases of laryngotracheal stenosis. Because of the rarity of relapsing polychondritis and lack of understanding of its pathogenesis, there is no standard medical therapy, and treatment is tailored according to disease activity and site of organ involvement. Read More

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http://dx.doi.org/10.1177/2050313X19832164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410384PMC

Relapsing polychondritis - analysis of symptoms and criteria.

Reumatologia 2019 28;57(1):8-18. Epub 2019 Feb 28.

Clinic of Rheumatology and Internal Medicine, Wrocław University Hospital, Poland.

Objectives: Relapsing polychondritis (RP) is a rare disease characterised by recurrent inflammation of the cartilaginous structures and proteoglycan-rich organs. The aim of this case series study is to share the 10-year clinical experience of our department in diagnosing RP patients in the context of data from available published studies.

Material And Methods: A retrospective case analysis of 10 patients with symptoms of RP, hospitalised at the Department of Rheumatology and Internal Diseases of Wrocław University Hospital between January 2008 and December 2018. Read More

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http://dx.doi.org/10.5114/reum.2019.83234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409832PMC
February 2019
1 Read

Clinical Characteristics of Relapsing Polychondritis: A Report of 8 Cases in Japan.

Kurume Med J 2019 Mar 11. Epub 2019 Mar 11.

Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine.

Objectives: Relapsing polychondritis (RP) is a very rare autoimmune disorder characterized by recurrent episodes of inflammation and destruction of cartilaginous tissues. We examined the clinical characteristics, management, and outcomes of Japanese RP patients.

Methods: We identified 8 RP cases in our department between 2003 and 2017. Read More

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https://www.jstage.jst.go.jp/article/kurumemedj/advpub/0/adv
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http://dx.doi.org/10.2739/kurumemedj.MS652006DOI Listing
March 2019
2 Reads

Relapsing periorbital polychondritis: a great ophthalmic masquerader.

Can J Ophthalmol 2019 Feb 25;54(1):e16-e18. Epub 2018 Jun 25.

Buckinghamshire Healthcare NHS Trust.

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http://dx.doi.org/10.1016/j.jcjo.2018.04.012DOI Listing
February 2019
1 Read

Relapsing polychondritis in medical practice of dermatovenerologist.

Ter Arkh 2018 Feb;90(1):65-68

State budgetary healthcare institution "Regional clinical hospital №2" MZ Krasnodar region, Krasnodar, Russia.

Recurrentpolyhedritis is a rare rheumatic disorder with a wave-like course, presumably ofautoimmune nature,characterizedbya widespread inflammatorylesion of the cartilaginous structures and other connective tissue of the ears, joints, nose, larynx, trachea, eyes, valvular heart, kidneys and blood vessels.The description of the own observation of recurrent polychondritis. Read More

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http://dx.doi.org/10.26442/terarkh201890165-68DOI Listing
February 2018
8 Reads

Kikuchi-Fujimoto disease with relapsing polychondritis.

Rheumatology (Oxford) 2019 Jan 28. Epub 2019 Jan 28.

Department of Internal Medicine (Rheumatology Unit), Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1093/rheumatology/key449DOI Listing
January 2019
1 Read
4.475 Impact Factor

Relapsing Polychondritis Associated With Psoriasis Vulgaris.

J Clin Rheumatol 2019 Jan 4. Epub 2019 Jan 4.

Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi 783-8505, Japan Laboratory of Anatomy, Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-Ku, Sapporo, 060-0818, Japan. Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi 783-8505, Japan.

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http://dx.doi.org/10.1097/RHU.0000000000000982DOI Listing
January 2019
3 Reads

Clinico-pathological profile and comparative study of conservative versus surgical deroofing as an effective technique in management of pseudocyst of pinna.

World J Otorhinolaryngol Head Neck Surg 2018 Dec 17;4(4):234-239. Epub 2018 Oct 17.

Department of ENT, Sur Hospital, South Sharqiya Region. Sur, Oman.

Background And Objectives: An auricular pseudocyst is not uncommon in routine ENT clinical practice, it occurs when fluid accumulates between the intracartilaginous spaces of the auricle. Many treatment modalities have been proposed such as incision and drainage of the cyst, simple needle aspiration, tight bandaging with dental rolls, however recurrence and cosmetic problems are still noted in some cases. The aim of this article was to discuss our experience of surgical treatment of intractable auricular pseudocysts with marsupialisation, deroofing and anterior cartilage leaflet removal along with compression suture therapy. Read More

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http://dx.doi.org/10.1016/j.wjorl.2018.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284201PMC
December 2018
4 Reads

[Misdiagnosis of relapsing polychondritis: report of 2 cases].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(19):1509-1510

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.19.018DOI Listing
October 2018

The relapsing polychondritis damage index (RPDAM): Development of a disease-specific damage score for relapsing polychondritis.

Joint Bone Spine 2018 Nov 15. Epub 2018 Nov 15.

Service de rhumatologie, centre de référence des maladies autoimmunes systemiques rares Est Sud-Ouest (RESO), hôpital de Hautepierre, 1, avenue Molière BP 83049, 67098 Strasbourg cedex, France; Inserm UMR-S1109, 67098 Strasbourg cedex, France. Electronic address:

Objectives: Relapsing polychondritis is a rare, multi-systemic and inflammatory condition of unknown origin. We currently lack a core set of measures to assess and follow damage in patients suffering from this condition. Our primary aim was to derive a disease-specific damage measuring tool for relapsing polychondritis, the Relapsing Polychondritis Damage Index (RPDAM). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183030
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http://dx.doi.org/10.1016/j.jbspin.2018.11.001DOI Listing
November 2018
21 Reads
2.901 Impact Factor

Limbic encephalitis with relapsing polychondritis: persistent white matter lesions and brain atrophy.

J Int Med Res 2018 Dec 14;46(12):5297-5302. Epub 2018 Nov 14.

1 Department of Neurology, Tianjin HuanHu Hospital, Tianjin, China.

Relapsing polychondritis (RP) is a rare autoimmune disorder affecting cartilage. Limbic encephalitis is a rare central nervous system manifestation of RP. This current case report describes a 66-year-old Chinese male patient who complained of developing myoclonus in the left leg, ataxia and speech difficulties 3 weeks prior to hospital admission. Read More

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http://journals.sagepub.com/doi/10.1177/0300060518805593
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http://dx.doi.org/10.1177/0300060518805593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300954PMC
December 2018
24 Reads

Clinicopathological case: rapid cognitive decline and myoclonus associated with fever, arthropathy and scleritis.

Pract Neurol 2019 Apr 13;19(2):147-155. Epub 2018 Nov 13.

Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK.

A 65-year-old man presented with transient neurological symptoms, followed by rapid cognitive decline, myoclonus and fevers. He had evidence of scleritis and an arthropathy. This paper reports the clinicopathological conference discussed at the Association of British Neurologists Annual Meeting 2017. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002013DOI Listing
April 2019
11 Reads

Relapsing Polychondritis with Meningoencephalitis Refractory to Immunosuppressant Therapy.

Case Rep Neurol Med 2018 3;2018:1873582. Epub 2018 Oct 3.

Clinical Assistant Professor, University of Illinois College of Medicine at Peoria, Peoria, IL, USA.

Meningoencephalitis is a rare complication of relapsing polychondritis. We report a case of a 25-year-old male who presented with visual hallucinations and symptoms of depression and anxiety, white matter changes on MRI, and CSF lymphocytosis, along with inflammatory chondritis seen in his auricle cartilage biopsy. Eventually he was given the diagnosis of RP presenting with meningoencephalitis based on CSF analysis, brain MRI findings, negative serologies, and neurologic exam findings. Read More

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https://www.hindawi.com/journals/crinm/2018/1873582/
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http://dx.doi.org/10.1155/2018/1873582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192138PMC
October 2018
12 Reads

Relapsing polychondritis: state of the art on clinical practice guidelines.

RMD Open 2018 18;4(Suppl 1):e000788. Epub 2018 Oct 18.

Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Centre National de Référence des Maladies Systémiques et Auto-immunes Rares (RESO), INSERM-UMRS 1109, F-67000, Strasbourg, France.

Due to the rarity of relapsing polychondritis (RP), many unmet needs remain in the management of RP. Here, we present a systematic review of clinical practice guidelines (CPGs) published for RP, as well as a list of the most striking unmet needs for this rare disease. We carried out a systematic search in PubMed and Embase based on controlled terms (medical subject headings and Emtree) and keywords of the disease and publication type (CPGs). Read More

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http://rmdopen.bmj.com/lookup/doi/10.1136/rmdopen-2018-00078
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http://dx.doi.org/10.1136/rmdopen-2018-000788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203097PMC
October 2018
17 Reads

[The Characteristics of Imaging, Fiber-bronchoscope and Pulmonary Function Testing of Relapsing Polychondritis Patients with Respiratory Symptoms].

Sichuan Da Xue Xue Bao Yi Xue Ban 2018 Sep;49(5):803-807

Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China.

Objective: To analyze the characteristics of clinical manifestation, imaging, fiber-bronchoscope finding and pulmonary function testing in the patients of relapsing polychodriti with respiratory symptoms.

Methods: The clinical data of 33 patients with RP in West China Hospital of Sichuan University from May 2007 to May 2017 were analyzed retrospectively. The patients were divided into respiratory group (21 cases) and non-respiratory group (12 cases) based on whether the respiratory symptoms were main involvement, and the data of the two groups were statistically analyzed. Read More

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September 2018
9 Reads

Update on Vertigo in Autoimmune Disorders, from Diagnosis to Treatment.

J Immunol Res 2018 26;2018:5072582. Epub 2018 Sep 26.

Department of Neurosciences, Otorhinolaryngology Unit, University of Padua, Via Giustiniani, 2, 35128 Padova, Italy.

The prevalence of autoimmune diseases has been increasing over the last 20 years. The clinical presentation of this large and heterogeneous group of disorders depends on whether the involvement is organ-specific or non-organ-specific. Dizziness, vertigo, and disequilibrium are common symptoms reported by patients with vestibulocochlear involvement. Read More

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http://dx.doi.org/10.1155/2018/5072582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178164PMC
December 2018
4 Reads

Reclassifying Idiopathic Uveitis: Lessons From a Tertiary Uveitis Center.

Am J Ophthalmol 2019 Feb 22;198:193-199. Epub 2018 Oct 22.

Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA; Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA; Legacy Devers Eye Institute, Legacy Health System, Portland, Oregon, USA. Electronic address:

Purpose: Idiopathic uveitis is frequently the most common diagnosis in series from uveitis clinics. This study sought to determine the percentage of patients initially diagnosed as idiopathic, noninfectious uveitis referred to a tertiary uveitis center who were subsequently found to have an identifiable cause of uveitis.

Design: Retrospective case series. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029394183060
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http://dx.doi.org/10.1016/j.ajo.2018.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349540PMC
February 2019
12 Reads

Relapsing polychondritis patients were divided into three subgroups: patients with respiratory involvement (R subgroup), patients with auricular involvement (A subgroup), and overlapping patients with both involvements (O subgroup), and each group had distinctive clinical characteristics.

Medicine (Baltimore) 2018 Oct;97(42):e12837

Department of Immunology and Medicine, Institute of Medical Science, and Division of Rheumatology and Allergology, St. Marianna University School of Medicine, Kawasaki, Japan.

Relapsing polychondritis (RP) is a multisystem disorder of cartilaginous tissues. Previously, we found that patients with respiratory involvement and patients with auricular involvement were mutually exclusive in the RP cohort, which suggests a strong inverse relationship between respiratory and auricular involvement. Here, we examined the clinical manifestation patterns in a subgroup of patients with respiratory involvement (R subgroup) and a subgroup of patients with auricular involvement (A subgroup) and investigated the clinical and laboratory characteristics of each subgroup. Read More

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http://dx.doi.org/10.1097/MD.0000000000012837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211876PMC
October 2018
2 Reads

Scleromyxoedema: the importance of physical examination.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Unit of Clinical Immunology, Centro Hospitalar Porto, Porto, Portugal.

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22714
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http://dx.doi.org/10.1136/bcr-2018-227144DOI Listing
October 2018
13 Reads

Clinical features of Chinese patients with relapsing polychondritis.

Br J Ophthalmol 2018 Oct 12. Epub 2018 Oct 12.

University Eye Clinic Maastricht, Maastricht, The Netherlands.

Purpose: To characterise the ocular and extraocular findings in patients with relapsing polychondritis (RP) patients.

Design: Retrospective, longitudinal study.

Methods: A total number of 16 patients with ocular RP, seen in our tertiary uveitis referral centre over a time period of 10 years were included in this study. Read More

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3126
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http://dx.doi.org/10.1136/bjophthalmol-2018-312660DOI Listing
October 2018
13 Reads

Case report of mixed-type autoimmune hemolytic anemia in a patient with relapsing polychondritis.

Medicine (Baltimore) 2018 Oct;97(40):e12716

Department of Rheumatology and Immunology, Xiangya Hospital.

Rationale: Relapsing polychondritis (RP) is a rare autoimmune-related disease and may be associated with other autoimmune diseases.

Patient Concerns: Here we reported a case of RP patients with mixed-type AIHA. The patient was diagnosed with RP in March 2008 which was treated and the patient was in stable condition. Read More

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http://dx.doi.org/10.1097/MD.0000000000012716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200522PMC
October 2018
4 Reads

Propionate-producing bacteria in the intestine may associate with skewed responses of IL10-producing regulatory T cells in patients with relapsing polychondritis.

PLoS One 2018 20;13(9):e0203657. Epub 2018 Sep 20.

Department of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.

Relapsing polychondritis (RP) is an inflammatory disease of unknown causes, characterized by recurrent inflammation in cartilaginous tissues of the whole body. Recently, researchers have reported that, in mouse experiments, altered gut microbe-dependent T cell differentiation occurred in gut associated lymphoid tissues. Here, we investigated whether gut microbe alteration existed, and if so, the alteration affected peripheral T cell differentiation in patients with RP. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203657PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147427PMC
March 2019
3 Reads

Bilateral Panuveitis and Keratitis as First Presentation of Relapsing Polychondritis.

Ocul Immunol Inflamm 2018 Sep 7:1-3. Epub 2018 Sep 7.

a Eye Research Center , Mashhad University of Medical Sciences , Mashhad , Iran.

Purpose: To report a rare case of relapsing polychondritis with bilateral panuveitis as the first presentation of systemic disease Methods: A 26-year-old female presented with bilateral decreased vision, red eye and ocular pain underwent complete ocular examination, retinal imaging and systemic investigation.

Results: Investigations revealed bilateral panuveitis associated with keratitis, retinal hemorrhages and retinal vasculitis. Following systemic work-ups and the pinna cartilage biopsy, diagnosis of relapsing polychondritis was made. Read More

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http://dx.doi.org/10.1080/09273948.2018.1517893DOI Listing
September 2018
5 Reads

Tracheal enlargement or Mounier-Kuhn syndrome in giant cell arteritis: a possible causal association with therapeutic implications.

Rom J Morphol Embryol 2018 ;59(2):595-599

Department of Otorhinolaryngology, "Iuliu Haţieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania;

Giant cell arteritis (GCA) is a large-vessel vasculitis with rarely described respiratory initial manifestations. We report such a case presenting with hoarseness, stridor, cough and dyspnea, in which a tracheomegaly with tracheomalacia was found. No signs of relapsing polychondritis were present. Read More

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December 2018
5 Reads

In search of chondrocyte-specific antigen.

Cent Eur J Immunol 2018 30;43(2):132-138. Epub 2018 Jun 30.

Department of Histology and Embryology, Medical University of Warsaw, Poland.

The purpose of this work was to establish, whether rat chondrocyte associated antigen, transmembrane Tmp21 protein belonging to the p24 protein family may immunize rats and thus be included into the panel of immunogens potentially involved in cartilage pathology. For immunization of rats extract from cultured chondrocytes containing surface chondrocyte proteins suspended in incomplete Freund's adjuvant was used. Control animals were injected with incomplete Freund's adjuvant without chondrocyte extract. Read More

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http://dx.doi.org/10.5114/ceji.2018.77382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102620PMC
June 2018
4 Reads

Relapsing Polychondritis Manifesting as Tracheal and Costochondral Inflammation on Magnetic Resonance Imaging.

J Clin Rheumatol 2018 Aug 13. Epub 2018 Aug 13.

Department of Radiology, Landstuhl Regional Medical Center, Landstuhl, Germany.

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http://dx.doi.org/10.1097/RHU.0000000000000887DOI Listing
August 2018
15 Reads

Observational study and brief analysis of diagnostic criteria in relapsing polychondritis.

Rheumatol Int 2018 Nov 6;38(11):2095-2101. Epub 2018 Aug 6.

Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany.

Observational study of patients with relapsing polychondritis (RPC) and brief evaluation of widely used diagnostic criteria. A retrospective analysis of 18 patients with RPC treated in the past 15 years at the Charté-Universitätsmedizin Berlin was performed. Three different diagnostic criteria were applied to our cohort. Read More

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http://dx.doi.org/10.1007/s00296-018-4121-2DOI Listing
November 2018
4 Reads

Relapsing Polychondritis: An Updated Review.

Biomedicines 2018 Aug 2;6(3). Epub 2018 Aug 2.

Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, 98125 Messina, Italy.

Relapsing polychondritis is an immune-mediated systemic disease characterized by recurrent episodes of inflammation of cartilaginous and proteoglycan-rich tissues, resulting in progressive anatomical deformation and functional impairment of the involved structures. Auricular and nasal chondritis and/or polyarthritis represent the most common clinical features, but potentially all types of cartilage may be involved. Because of the pleomorphic nature of the disease, with non-specific symptoms at the onset, the diagnosis of relapsing polychondritis is often delayed. Read More

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http://dx.doi.org/10.3390/biomedicines6030084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164217PMC
August 2018
16 Reads

Relapsing Polychondritis following Treatment with Secukinumab for Ankylosing Spondylitis: Case Report and Review of the Literature.

Case Rep Rheumatol 2018 2;2018:6760806. Epub 2018 Jul 2.

University of Michigan Medical School, Ann Arbor, MI, USA.

Relapsing polychondritis (RP) is an autoimmune disorder that often occurs concomitantly with other autoimmune diseases, though RP has been infrequently associated with ankylosing spondylitis (AS). There is a small, but growing, body of the literature demonstrating case reports describing RP secondary to AS in patients treated with tumor necrosis alpha inhibitors (TNFi's). We present the first case in which RP developed in AS while treated with an interleukin 17A inhibitor (IL-17Ai), secukinumab. Read More

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http://dx.doi.org/10.1155/2018/6760806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051248PMC
July 2018
4 Reads

Severe panuveitis with relapsing polychondritis.

Am J Ophthalmol Case Rep 2018 Sep 20;11:3-5. Epub 2018 Apr 20.

Department of Ophthalmology, Nara Medical University, Kashihara, 634-8522 Nara, Japan.

Purpose: Relapsing polychondritis is a rare multiorgan disease characterized by repeated episodes of inflammation and deterioration of cartilages. We report a case of relapsing polychondritis that presented with severe panuveitis.

Observations: A 53-year-old man visited our hospital because of ocular pain in both eyes of 2 weeks' duration. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.04.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058060PMC
September 2018
16 Reads

Less common rheumatologic disorders: Current concepts of skin and systemic manifestations.

Authors:
Taraneh Paravar

Clin Dermatol 2018 Jul - Aug;36(4):525-532. Epub 2018 Apr 10.

Department of Dermatology, University of California-San Diego School of Medicine, San Diego, California, USA. Electronic address:

The cutaneous manifestations of the common rheumatologic disorders, such as systemic lupus erythematosus, dermatomyositis, and systemic sclerosis, are well known. In contrast, the dermatologic findings of less common rheumatologic disorders, including Sjögren syndrome, mixed connective tissue disease, and relapsing polychondritis, are less widely known. The cutaneous manifestations of these connective tissue disorders are reviewed. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2018.04.009DOI Listing
December 2018
4 Reads

Relapsing polychondritis case.

Authors:
Christopher Lam

Can Fam Physician 2018 Jul;64(7):488

Victoria, BC.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042656PMC
July 2018
3 Reads

Indications and Long-term Outcomes of Open Augmentation Rhinoplasty with Autogenous L-shaped Costal Cartilage Strut Grafts - A Single Plastic Surgeon's Experience.

Otolaryngol Pol 2018 Jun;72(3):26-32

Department of Plastic and Reconstructive Surgery, Addenbrooke's University Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Postgraduate Medical Institute, Faculty of Medical Sciences, Anglia Ruskin University, Cambridge & Chelmsford, UK.

Introduction We present a single surgeon's experience of open augmentation rhinoplasty with autogenous L-shaped costal cartilage grafts, with long-term patient-reported outcome data. We highlight the salient operative steps and outline the peri-operative care required to optimise outcomes. Materials and Methods A retrospective review of eleven such augmentation rhinoplasties performed between 2008 and 2016 was undertaken. Read More

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http://dx.doi.org/10.5604/01.3001.0011.7258DOI Listing
June 2018
6 Reads

Ear Involvement in Inflammatory Bowel Disease: A Review of the Literature.

J Clin Med Res 2018 Aug 27;10(8):609-614. Epub 2018 Jun 27.

Department of Gastroenterology, Medical School of Ioannina, Ioannina, Greece.

Inflammatory bowel disease (IBD) is a multisystemic disease. The ear is a rare but recognized site of extraintestinal manifestations of IBD. In external ear, the more common manifestations of IBD are pyoderma gangrenosum, metastatic Crohn's disease and relapsing polychondritis and the treatment includes corticosteroids and anti-TNF agents. Read More

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http://www.jocmr.org/index.php/JOCMR/article/view/3465
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http://dx.doi.org/10.14740/jocmr3465wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031254PMC
August 2018
16 Reads

Cartilage diseases.

Matrix Biol 2018 10 24;71-72:51-69. Epub 2018 May 24.

Department of Biological Engineering, MIT, Cambridge, MA 02139, USA; Department of Mechanical Engineering, MIT, Cambridge, MA 02139, USA; Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA 02139, USA. Electronic address:

Hyaline cartilages, fibrocartilages and elastic cartilages play multiple roles in the human body including bearing loads in articular joints and intervertebral discs, providing joint lubrication, forming the external ears and nose, supporting the trachea, and forming the long bones during development and growth. The structure and organization of cartilage's extracellular matrix (ECM) are the primary determinants of normal function. Most diseases involving cartilage lead to dramatic changes in the ECM which can govern disease progression (e. Read More

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http://dx.doi.org/10.1016/j.matbio.2018.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146013PMC
October 2018
26 Reads

[Efficacy analysis of T type tube dilatation in adult cervical tracheal stenosis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Mar;32(5):372-374

Department of Otolaryngology Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China.

To investigate the efficacy, recurrence and strategy of T silicone tube dilatation for cicatricial stenosis of cervical trachea in adults.Cinical data of 37 cases with the cervical tracheal stenosis were retrospectively analyzed, who were firstly treated by T shape silicone tube dilation for at least 10 months, from Jun 2006 to Jun 2016.In 37 adult patients with cicatricial stenosis of the trachea, 29 cases were caused by tracheal intubation or incision, 6 cases were traumatic, and 2 cases were multiple osteochondritis. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.05.013DOI Listing
March 2018
5 Reads

Clinical characteristics and ocular complications of patients with scleritis in Japanese.

Jpn J Ophthalmol 2018 Jul 23;62(4):517-524. Epub 2018 May 23.

Department of Ophthalmology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Purpose: To investigate the clinical characteristics of Japanese patients with scleritis STUDY DESIGN: Retrospective study METHODS: The clinical records of 123 patients with scleritis, who presented to the University of Tokyo Hospital between January, 2004 and December, 2015, were retrospectively reviewed.

Results: The cohort comprised 55 men and 68 women (mean age, 57.8±16. Read More

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http://link.springer.com/10.1007/s10384-018-0600-y
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http://dx.doi.org/10.1007/s10384-018-0600-yDOI Listing
July 2018
10 Reads

Anti-neutrophil cytoplasmic antibody-associated glomerulonephritis with detection of myeloperoxidase and phospholipase A receptor in membranous nephropathy-lesions: report of two patients with microscopic polyangiitis.

BMC Nephrol 2018 05 23;19(1):120. Epub 2018 May 23.

Department of Nephrology and Endocrinology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan.

Background: Podocyte phospholipase A receptor (PLAR) is a major target antigen in idiopathic adult membranous nephropathy (MN). Histological PLAR staining in the renal tissue has proven to be useful for the detection of idiopathic MN. However, glomerular PLAR deposits have also been recently observed in several patients with secondary MN, such as hepatitis B virus-associated, hepatitis C virus-associated, and neoplasm-associated MN. Read More

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http://dx.doi.org/10.1186/s12882-018-0922-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966893PMC
May 2018
11 Reads

Hypocomplementemic urticarial vasculitis occurring in a patient with relapsing polychondritis.

Int J Dermatol 2018 11 20;57(11):1363-1364. Epub 2018 May 20.

University of Tunis El Manar, Department of Dermatology, Charles Nicolle Hospital, Tunis, Tunisia.

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http://dx.doi.org/10.1111/ijd.14051DOI Listing
November 2018
11 Reads

Persistent unilateral ulcer of the ear as the first manifestation of relapsing polychondritis.

Clin Exp Dermatol 2018 10 16;43(7):823-824. Epub 2018 May 16.

Experimental and Clinical Medicine Department, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1111/ced.13615DOI Listing
October 2018
3 Reads

Red-eared zebra diagnosis: Case of relapsing polychondritis.

Can Fam Physician 2018 May;64(5):363-367

Clinical Assistant Professor in the Department of Family Medicine at the University of Alberta.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951651PMC
May 2018
5 Reads

Tofacitinib in steroid-dependent relapsing polychondritis.

Ann Rheum Dis 2018 May 3. Epub 2018 May 3.

Tareev Clinic of Internal Diseases, Sechenov First Moscow State Medical University, Moscow, Russia.

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http://dx.doi.org/10.1136/annrheumdis-2018-213554DOI Listing
May 2018
10 Reads

Relapsing Polychondritis.

N Engl J Med 2018 May;378(18):1715

University of Missouri, Columbia, MO.

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http://dx.doi.org/10.1056/NEJMicm1713302DOI Listing
May 2018
5 Reads

Relapsing polychondritis: a diagnosis not to be missed.

Rheumatology (Oxford) 2018 10;57(10):1768

Institute for Autoimmune Systemic and Neurological Diseases, Athens, Greece.

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http://dx.doi.org/10.1093/rheumatology/key124DOI Listing
October 2018
6 Reads

Remission of relapsing polychondritis after successful treatment of myelodysplastic syndrome with azacitidine: a case and review of the literature.

Drug Metab Pers Ther 2018 Jun;33(2):105-108

Hacettepe University Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey.

Background: Relapsing polychondritis (RP) is a rare autoimmune disorder, and myelodysplastic syndrome (MDS) is accompanied by RP at variable rates. Herein, we report a case with RP and MDS who responded dramatically to 5-azacitidine for MDS.

Case Presentation: With conventional immunosuppressive treatment, our patient had several episodes of different side effects, including infections. Read More

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http://dx.doi.org/10.1515/dmpt-2018-0002DOI Listing
June 2018
9 Reads

Pleocytosis in a patient with relapsing polychondritis accompanied by meningoencephalitis: a case report.

Authors:
Jie Cao Min Zhang

BMC Neurol 2018 Apr 25;18(1):53. Epub 2018 Apr 25.

Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, 430030, China.

Background: Relapsing polychondritis (RP) is an uncommon immune-related disease with unknown causes. It is characterized by inflammation of cartilaginous or non-cartilaginous structures, such as the ears, nose, respiratory tract, eyes, and joints. Neurological involvement is rare in RP. Read More

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http://dx.doi.org/10.1186/s12883-018-1059-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921442PMC
April 2018
8 Reads

How to conduct research of rare autoimmune diseases.

Authors:
Chikashi Terao

Mod Rheumatol 2018 Sep 22;28(5):766-769. Epub 2018 May 22.

a Laboratory for Statistical Analysis , RIKEN Center for Integrative Medical Sciences , Yokohama , Japan.

Rare autoimmune diseases are difficult to conduct researches in spite of present era with advanced scientific progress. Research using genetic approach is a promising way since genetic findings implicate causality of diseases. Still, there are multiple obstacles preventing genetic studies of rare diseases. Read More

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http://dx.doi.org/10.1080/14397595.2018.1465632DOI Listing
September 2018
6 Reads

Efficacy and safety of biologics in relapsing polychondritis: a French national multicentre study.

Ann Rheum Dis 2018 Aug 13;77(8):1172-1178. Epub 2018 Mar 13.

UMR 1027, INSERM, University of Toulouse, Toulouse, France.

Objectives: To assess the efficacy and the safety of biologics in a cohort of patients with relapsing polychondritis (RP).

Methods: We conducted a French multicentre retrospective cohort study including patients treated with biologics for RP. Efficacy outcomes were clinical response (partial or complete) and complete response during the first 6 months of exposure, plus daily corticosteroid dose at 6 months. Read More

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http://dx.doi.org/10.1136/annrheumdis-2017-212705DOI Listing
August 2018
16 Reads
1 Citation
10.380 Impact Factor

Three Cases of Relapsing Polycondritis with Isolated Laryngotracheal Stenosis.

Turk Arch Otorhinolaryngol 2017 Jun 1;55(2):77-82. Epub 2017 Jun 1.

Clinic of Otorhinolaryngology, Gülhane Training and Research Hospital, Ankara, Turkey.

Relapsing polychondritis (RP) is a rare autoimmune and inflammatory disease, particularly characterized by recurrent inflammation of the hyaline cartilage. Laryngotracheal involvement in RP is the most serious complication that is observed in 50% of the patients and may lead to a life-threatening condition. The most common cause of death is laryngotracheal stenosis associated with lung infections or severe respiratory insufficiency that may be observed in 10%-50% of the patients. Read More

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http://dx.doi.org/10.5152/tao.2017.2236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782947PMC
June 2017
6 Reads

Refractory relapsing polychondritis: challenges and solutions.

Open Access Rheumatol 2018 9;10:1-11. Epub 2018 Jan 9.

Department of Rheumatology, Henri Mondor Hospital, University Paris 12, Créteil, France.

Relapsing polychondritis is a severe systemic immune-mediated disease characterized by an episodic and progressive inflammatory condition with progressive destruction of cartilaginous structures. This disease has for nearly a century kept secrets not yet explained. The real incidence and prevalence of this rare disease are unknown. Read More

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http://dx.doi.org/10.2147/OARRR.S142892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768290PMC
January 2018
7 Reads