77 results match your criteria Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego[Journal]


The use of mesenchymal stem cells for the treatment of progressive retinal diseases: a review.

Regen Med 2019 Apr 12. Epub 2019 Apr 12.

Polski Bank Komórek Macierzystych SA (FamiCord Group), Jana Pawła II 29, 00-867 Warsaw, Poland.

Some ocular diseases, such as dystrophies, retinal and macular degeneration, optic nerve atrophy, and Stargardt disease, are progressive and irreversible. In this review, we focus on the use of mesenchymal stem cells (MSCs) in the treatment of these diseases. In animal studies, MSC transplantation significantly delayed retinal degeneration, led to the regeneration of cone cells, and supported the survival of retinal ganglion cells and axon regeneration. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/rme-2019-0022DOI Listing

The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again.

Cancers (Basel) 2019 02 21;11(2). Epub 2019 Feb 21.

Inserm U1065, Centre Méditerranéen de Médecine Moléculaire (C3M), FHU OncoAge, Université Côte d'Azur, 06200 Nice, France.

It is generally accepted that carcinogenesis and aging are two biological processes, which are known to be associated. Notably, the frequency of certain cancers (including lung cancer), increases significantly with the age of patients and there is now a wealth of data showing that multiple mechanisms leading to malignant transformation and to aging are interconnected, defining the so-called common biology of aging and cancer. OncoAge, a consortium launched in 2015, brings together the multidisciplinary expertise of leading public hospital services and academic laboratories to foster the transfer of scientific knowledge rapidly acquired in the fields of cancer biology and aging into innovative medical practice and silver economy development. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers11020250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406685PMC
February 2019
2 Reads

Stereocontrolled Synthesis of Chiral Heteroaromatic Propellers with Small Optical Bandgaps.

Angew Chem Int Ed Engl 2019 Apr 18;58(15):4929-4933. Epub 2019 Feb 18.

Wydział Chemii, Uniwersytet Wrocławski, ul. F. Joliot-Curie 14, 50-383, Wrocław, Poland.

Chiral heteroaromatic propellers based on radially π-extended hexapyrrolohexaazacoronenes were obtained in a concise synthesis from suitably functionalized donor-acceptor monopyrroles. To overcome steric hindrance, a new cyclodehydrogenation method was developed, and it uses bromine electrophiles as oxidative coupling agents instead of the commonly employed high-potential oxidants. The new reaction offers high yields of propeller-shaped targets, even for electron-deficient precursors, and shows electrophile-dependent stereoselectivity, with N-bromosuccinimide and dibromine yielding, respectively D - and C -symmetric products. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201900175DOI Listing

Safety of intrathecal injection of Wharton's jelly-derived mesenchymal stem cells in amyotrophic lateral sclerosis therapy.

Neural Regen Res 2019 Feb;14(2):313-318

Department of Neurology and Neurosurgery, School of Medicine, Collegium Medicum - University of Warmia and Mazury in Olsztyn; University Clinical Hospital in Olsztyn, Olsztyn, Poland.

Animal experiments have confirmed that mesenchymal stem cells can inhibit motor neuron apoptosis and inflammatory factor expression and increase neurotrophic factor expression. Therefore, mesenchymal stem cells have been shown to exhibit prospects in the treatment of amyotrophic lateral sclerosis. However, the safety of their clinical application needs to be validated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/1673-5374.243723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301165PMC
February 2019
3 Reads

An FEP Microfluidic Reactor for Photochemical Reactions.

Micromachines (Basel) 2018 Mar 30;9(4). Epub 2018 Mar 30.

Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.

Organic syntheses based on photochemical reactions play an important role in the medical, pharmaceutical, and polymeric chemistry. For years, photochemistry was performed using high-pressure mercury lamps and immersion-wells. However, due to excellent yield, control of temperature, selectivity, low consumption of reagents and safety, the microreactors made of fluorinated ethylene propylene (FEP) tubings have recently been used more frequently. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/mi9040156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187735PMC

Extending far and wide: the role of biopsy and staging in the management of ocular surface squamous neoplasia.

Clin Exp Ophthalmol 2019 Mar 13;47(2):193-200. Epub 2018 Nov 13.

Department of Ophthalmology, USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California.

Importance: Although the most recent American Joint Committee on cancer staging guidelines for ocular surface squamous neoplasia place a heightened emphasis on biopsy and histopathologic analysis, the interpretation and clinical relevance of these staging criteria are not always clear. We address limitations of using histopathologic analysis to predict clinical outcomes and suggest less-invasive assessments.

Background: To investigate the impact of histopathologic depth of invasion on outcomes for tumours with the common presentation of multiple structure involvement. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ceo.13382DOI Listing
March 2019
8 Reads

Conjunctival Squamous Neoplasia: Staging and Initial Treatment.

Cornea 2018 Oct;37(10):1287-1291

Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH.

Purpose: To evaluate the clinical relevance of the American Joint Committee on Cancer (AJCC) classification in the initial management of squamous neoplasia of the conjunctiva.

Methods: This retrospective study enrolled 95 histopathologically proven cases of treatment-naive conjunctival squamous neoplasia. Tumors were classified into 4 histological groups: conjunctival intraepithelial neoplasia (CIN) with mild dysplasia (grade 1/3), moderate dysplasia (grade 2/3), severe dysplasia (grade 3/3 or carcinoma in situ), and invasive squamous cell carcinoma (SCC). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ICO.0000000000001651DOI Listing
October 2018
4 Reads

Identification of the mutation causing progressive retinal atrophy in Old Danish Pointing Dog.

Anim Genet 2018 Jun 6;49(3):237-241. Epub 2018 Apr 6.

Animal Genetics, Bioinformatics & Breeding, Department of Veterinary & Animal Sciences, Faculty of Health & Medical Sciences, University of Copenhagen, Grønnegårdsvej 3, DK-1870, Frederiksberg C, Denmark.

Progressive retinal atrophy (PRA) is a common cause of blindness in many dog breeds. It is most often inherited as a simple Mendelian trait, but great genetic heterogeneity has been demonstrated both within and between breeds. In many breeds the genetic cause of the disease is not known, and until now, the Old Danish Pointing Dog (ODP) has been one of those breeds. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/age.12659DOI Listing

Corpuls CPR Generates Higher Mean Arterial Pressure Than LUCAS II in a Pig Model of Cardiac Arrest.

Biomed Res Int 2017 17;2017:5470406. Epub 2017 Dec 17.

Institute for Translational Cardiac Surgery (INSURE), Department of Cardiovascular Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.

According to the European Resuscitation Council guidelines, the use of mechanical chest compression devices is a reasonable alternative in situations where manual chest compression is impractical or compromises provider safety. The aim of this study is to compare the performance of a recently developed chest compression device (Corpuls CPR) with an established system (LUCAS II) in a pig model. . Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2017/5470406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748132PMC

Do olfactory behaviour and marking responses of Konik polski stallions to faeces from conspecifics of either sex differ?

Behav Processes 2018 Oct 27;155:38-42. Epub 2017 Sep 27.

Institute of Genetics and Animal Breeding of Polish Academy of Sciences, Department of Animal Behaviour, Jastrzębiec, 05-552 Magdalenka, Poland.

The aim of the study was to assess whether adult stallions differentiate their olfactory and marking behaviour towards the excreta of their potential male rivals and mares. Four Konik polski stallions were individually exposed simultaneously to their own and each others' faeces as well as faeces of mares in oestrus vs. dioestrus. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.beproc.2017.09.015DOI Listing
October 2018
8 Reads

Narrow Networks on the Individual Marketplace in 2017.

LDI Issue Brief 2017 09;21(8):1-6

Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA.

This Issue Brief describes the breadth of physician networks on the ACA marketplaces in 2017. We find that the overall rate of narrow networks is 21%, which is a decline since 2014 (31%) and 2016 (25%). Narrow networks are concentrated in plans sold on state-based marketplaces, at 42%, compared to 10% of plans on federally-facilitated marketplaces. Read More

View Article

Download full-text PDF

Source
September 2017
1 Read

[Membranous nephropathy: Pathophysiology and natural history].

Nephrol Ther 2017 Apr;13 Suppl 1:S75-S81

Service de néphrologie, hôpital Pasteur, université de Nice-Sophia Antipolis, CHU de Nice, 30, voie romaine, CS 51069, 06001 Nice cedex 1, France.

Membranous nephropathy is a major cause of nephrotic syndrome in adults, with various etiologies and outcomes. One third of patients enter spontaneous remission with blockade of the renin-angiotensin system, one third develop a persistent nephrotic syndrome, while another third of patients develop end-stage kidney disease and 40% of them relapse after kidney transplantation. Treatment of membranous nephropathy remains controversial. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nephro.2017.01.012DOI Listing
April 2017
32 Reads

Corpuls cpr resuscitation device generates superior emulated flows and pressures than LUCAS II in a mechanical thorax model.

Australas Phys Eng Sci Med 2017 Jun 3;40(2):441-447. Epub 2017 Mar 3.

Department of Cardiovascular Surgery, Division of Experimental Surgery, German Heart Center Munich, Munich Heart Alliance, Lazarettstrasse 36, 80636, Munich, Germany.

The provision of sufficient chest compression is among the most important factors influencing patient survival during cardiopulmonary resuscitation (CPR). One approach to optimize the quality of chest compressions is to use mechanical-resuscitation devices. The aim of this study was to compare a new device for chest compression (corpuls cpr) with an established device (LUCAS II). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13246-017-0537-3DOI Listing
June 2017
45 Reads

Development and validation of an improved mechanical thorax for simulating cardiopulmonary resuscitation with adjustable chest stiffness and simulated blood flow.

Med Eng Phys 2017 05 24;43:64-70. Epub 2017 Feb 24.

Department of Experimental Surgery, Clinic for Cardiovascular Surgery, German Heart Center, Technische Universität München, Munich 80636, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany. Electronic address:

Investigations of compressive frequency, duty cycle, or waveform during CPR are typically rooted in animal research or computer simulations. Our goal was to generate a mechanical model incorporating alternate stiffness settings and an integrated blood flow system, enabling defined, reproducible comparisons of CPR efficacy. Based on thoracic stiffness data measured in human cadavers, such a model was constructed using valve-controlled pneumatic pistons and an artificial heart. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.medengphy.2017.02.005DOI Listing
May 2017
17 Reads

[Treatment of cough in respiratory tract infections - the effect of combining the natural active compounds with thymol].

Wiad Lek 2016;69(6):791-798

Zakład Ekomoniki i Organizacji Ochrony Zdrowia, Narodowy Instytut Zdrowia Publicznego- Państwowy Zakład Higieny, Warszawa, Polska, Katedra Zdrowia Publicznego, Uniwersytet Medyczny we Wrocławiu, Polska.

Cough is one of the characteristic symptoms of upper respiratory tract infections (URI). Herbal medicines are often used in the treatment of the cough associated with infection and to accelerate recovery or support the immune system. An example of such products are extracts of thyme and primrose, and also their combination with thymol. Read More

View Article

Download full-text PDF

Source
July 2017
26 Reads

Novel Antibacterial Compounds and their Drug Targets - Successes and Challenges.

Curr Med Chem 2017 ;24(18):1948-1982

Department of Organic Chemistry, Faculty of Pharmacy with Division of Medical Analytics, 4A Chodzki St., PL-20093 Lublin. Poland.

Infectious diseases are one of the most important and urgent health problems in the world. According to the World Health Organization (WHO) statistics, infectious and parasitic diseases are a cause of about 16% of all deaths worldwide and over 40% of deaths in Africa. A considerable progress that has been made during last hundred years in the fight against infectious diseases, in particular bacterial infections, can be attributed mainly to three factors: (1) the general improvement of living conditions, in particular sanitation; (2) development of vaccines and (3) development of efficient antibacterial drugs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/0929867323666161213102127DOI Listing
November 2017
3 Reads

Bridging Social Capital and Individual Earnings: Evidence for an Inverted U.

Soc Indic Res 2016;127:601-631. Epub 2015 May 23.

Department of Quantitative Economics, Warsaw School of Economics, al. Niepodległości 162, 02-554 Warsaw, Poland ; Narodowy Bank Polski, ul. Świętokrzyska 11/21, 00-919 Warsaw, Poland.

Based on data on a cross section of individuals surveyed in the 1999-2002 wave of World and European Values Surveys, we investigate the multilateral associations between bridging social capital, individuals' earnings, as well as social trust and employment status. Our analysis provides robust evidence that the relationship between bridging social capital and earnings is inverted-U shaped. We carry out a range of tests in order to ascertain that this result is not driven by regressor endogeneity or omitted variables bias. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11205-015-0980-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867891PMC

Influence of Polymer Type on the Physical Properties and Release Profile of Papaverine Hydrochloride From Hard Gelatin Capsules.

Polim Med 2015 Jul-Dec;45(2):51-5

Department of Applied Pharmacy, Medical University of Lublin, Lublin, Poland.

Background: The capsule is one of the most important solid dosage forms in the pharmaceutical industry. It is easier and faster to produce than a tablet, because it requires fewer excipients. Generally, capsules are easy to swallow and mask any unpleasant taste of the substances used while their release profiles can be easily modified. Read More

View Article

Download full-text PDF

Source
June 2016
11 Reads

Letters To The Editor.

Authors:
Adam Dziki

Pol Przegl Chir 2015 Sep;87(9):482-3

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/pjs-2015-0092DOI Listing
September 2015
1 Read

Dissolution Studies of Papaverine Hydrochloride from Tablets in Three Pharmacopoeia Apparatuses.

Polim Med 2015 Jan-Jun;45(1):21-4

Background: In tablet production, the most important aspects are the physical properties of the tablets and their dissolution studies, which can be performed in four pharmacopoeial apparatuses. There are differences between them in construction and action, so differences in the results obtained are possible.

Objectives: The aim of the study was to compare the release of a model drug substance (papaverine hydrochloride) from tablets in three pharmacopoeial dissolution apparatus: a basket, a paddle (closed system) and flow-through cell (open system). Read More

View Article

Download full-text PDF

Source
December 2015
43 Reads

Epitope Spreading of Autoantibody Response to PLA2R Associates with Poor Prognosis in Membranous Nephropathy.

J Am Soc Nephrol 2016 05 13;27(5):1517-33. Epub 2015 Nov 13.

Institut de Pharmacologie Moléculaire et Cellulaire, UMR 7275 CNRS and Université de Nice-Sophia Antipolis, Valbonne Sophia-Antipolis, France;

The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic membranous nephropathy. However, the value of anti-PLA2R1 antibody titers in predicting patient outcomes is unknown. Here, we screened serum samples from 50 patients positive for PLA2R1 for immunoreactivity against a series of PLA2R1 deletion mutants covering the extracellular domains. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1681/ASN.2014111061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849812PMC
May 2016
63 Reads

Novel retinopathy in related Gordon setters: a clinical, behavioral, electrophysiological, and genetic investigation.

Vet Ophthalmol 2016 Sep 29;19(5):398-408. Epub 2015 Sep 29.

Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, 7610001, Israel.

Purpose: To conduct ophthalmic, behavioral, electrophysiological, and genetic testing on two related Gordon setters presented for day blindness and compare findings with those of nine related and unrelated Gordon setters.

Methods: All dogs underwent comprehensive ophthalmic examination. Maze testing was conducted under different light intensities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/vop.12315DOI Listing
September 2016
4 Reads

Cross-reactivity of anti-PLA2R1 autoantibodies to rabbit and mouse PLA2R1 antigens and development of two novel ELISAs with different diagnostic performances in idiopathic membranous nephropathy.

Biochimie 2015 Nov 19;118:104-15. Epub 2015 Aug 19.

Institut de Pharmacologie Moléculaire et Cellulaire, UMR 7275 CNRS and Université de Nice-Sophia Antipolis, Valbonne Sophia-Antipolis, France. Electronic address:

About 70% of patients with idiopathic membranous nephropathy (iMN) have autoantibodies to the phospholipase A2 receptor PLA2R1. We screened sera from iMN patients for their cross-reactivity to human (h), rabbit (rb) and mouse (m) PLA2R1 by western blot (WB) and antigen-specific ELISAs. All iMN patients recognized hPLA2R1 and rbPLA2R1 by WB, and a rbPLA2R1 ELISA was as sensitive as the standardized hPLA2R1 ELISA to monitor anti-PLA2R1 in patients with active disease or in drug-induced remission. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2015.08.007DOI Listing
November 2015
58 Reads

Crystal structure of bis-(N-methyl-N-phenyl-amino)-tris-ulfane.

Acta Crystallogr E Crystallogr Commun 2015 Jul 24;71(Pt 7):836-9. Epub 2015 Jun 24.

Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA.

The title compound, C14H16N2S3, crystallized with two independent mol-ecules [(1 a ) and (1 b )] in the asymmetric unit. Both mol-ecules display a pseudo-trans conformation. The two consecutive S-S bond lengths of the tris-ulfane unit of mol-ecule (1 a ) are 2. Read More

View Article

Download full-text PDF

Source
http://scripts.iucr.org/cgi-bin/paper?S2056989015011342
Publisher Site
http://dx.doi.org/10.1107/S2056989015011342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518933PMC
July 2015
3 Reads

Progressive retinal atrophy in the Polski Owczarek Nizinny dog: a clinical and genetic study.

Vet Ophthalmol 2016 May 22;19(3):195-205. Epub 2015 May 22.

College of Veterinary Medicine, 900 East Campus Drive, Columbia, MO, 65211, USA.

Objective: To describe ophthalmic, functional, structural, and genetical characteristics of progressive retinal atrophy (PRA) in the polski owczarek nizinny (PON) breed of dog.

Animals Studied Clinically: Client-owned PON dogs (n = 82) from Sweden.

Procedures: Routine examination for presumed inherited eye disease was performed in all dogs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/vop.12284DOI Listing
May 2016
4 Reads

Three-dimensional grammar in the brain: Dissociating the neural correlates of natural sign language and manually coded spoken language.

Neuropsychologia 2015 May 6;71:191-200. Epub 2015 Apr 6.

Section for Sign Linguistics, Faculty of Polish Studies, University of Warsaw, Poland. Electronic address:

In several countries natural sign languages were considered inadequate for education. Instead, new sign-supported systems were created, based on the belief that spoken/written language is grammatically superior. One such system called SJM (system językowo-migowy) preserves the grammatical and lexical structure of spoken Polish and since 1960s has been extensively employed in schools and on TV. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuropsychologia.2015.03.031DOI Listing
May 2015
2 Reads

Release kinetics of papaverine hydrochloride from tablets with different excipients.

Sci Pharm 2014 Jul-Sep;82(3):684-96. Epub 2014 May 16.

Department of Applied Pharmacy, Faculty of Pharmacy, Medical University of Lublin, 1 Chodzki Str. 20-093, Lublin, Poland.

The influence of excipients on the disintegration times of tablets and the release of papaverine hydrochloride (PAP) from tablets were studied. Ten different formulations of tablets with PAP were prepared by direct powder compression. Different binders, disintegrants, fillers, and lubricants were used as excipients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3797/scipharm.1310-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318223PMC
April 2015
8 Reads

[Influence of polymer type on the physical properties and the release study of papaverine hydrochloride from tablets].

Polim Med 2014 Jan-Mar;44(1):5-12

Katedra i Zakład Farmacji Stosowanej, Wydział Farmaceutyczny, Uniwersytet Medyczny w Lublinie, Lublin, Polska.

Background: Polymers are widely used in drug manufacturing. Researchers studied their impact on the bioavailability of active substances or on physical properties of tablets for many years.

Objectives: To study the influence of polymer excipients, such as microcrystalline cellulose (Avicel PH 101, Avicel PH 102), croscarmellose sodium, crospovidone or polyvinylpyrrolidone, on the release profile of papaverine hydrochloride from tablets and on the physical properties of tablets. Read More

View Article

Download full-text PDF

Source
June 2014
5 Reads

Granulocyte, monocyte and blast immunophenotype abnormalities in acute myeloid leukemia with myelodysplasia-related changes.

Ann Clin Lab Sci 2014 ;44(1):3-9

USAMC, Department of Pathology, USAMC, Dept of Pathology, Mobile, AL 36617, USA; phone: 251 471 7787; fax: 251 471 7884; e mail:

Little literature exists regarding granulocyte and monocyte immunophenotype abnormalities in Acute Myeloid Leukemia (AML). We hypothesized that granulocyte and monocyte immunophenotype abnormalities are common in AML, and especially in AML with myelodysplasia-related changes (AMLMRC). Bone marrow or peripheral blood specimens from 48 cases of AML and 22 cases of control specimens were analyzed by flow cytometric immunophenotyping. Read More

View Article

Download full-text PDF

Source
May 2016
6 Reads

[Moral and religious issues in health care].

Authors:
Robert Necek

Przegl Lek 2012 ;69(6):271-4

Adiunkt w Katedrze Teologii Moralnej Ogólnej, Uniwersytet Papieski Jana Pawła II, Rzecznik Prasowy Archidiecezji Krakowskiej Konsultor ds. Srodków Społecznego Przekazu Konferencji Episkopatu Polski.

The paper summarises the moral and spiritual factors important in care for sick people. Medical care is one of the ancient forms of our activity as humans, expounding care for other people's well-being. The moral aspect of medical care is deeply rooted in constant daily interaction between the patient and the doctor aiming at easing symptoms, support, help, prevention and defense. Read More

View Article

Download full-text PDF

Source
November 2012
1 Read

Atypical angioimmunoblastic T-cell lymphomas masquerading as systemic polyclonal B-immunoblastic proliferation.

Virchows Arch 2012 Sep 12;461(3):323-31. Epub 2012 Jul 12.

Department of Pathology, University of South Alabama, Mobile, AL 36617, USA.

Angioimmunoblastic T cell lymphoma (AITL) is a relatively rare peripheral T cell lymphoma derived from follicular T helper cells. AITL has a varied presentation, both clinically and morphologically. AITL can pose a diagnostic challenge as it may be difficult to identify and characterize the neoplastic cells among the polymorphous infiltrates composed of polyclonal B immunoblasts and plasma cells. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-012-1280-5DOI Listing
September 2012
1 Read

Sensitivity and specificity of bone marrow hemophagocytosis in hemophagocytic lymphohistiocytosis.

Ann Clin Lab Sci 2012 ;42(1):21-5

Department of Pathology, University of South Alabama Medical Center, Mobile, AL 36617, USA.

Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal disease characterized by abnormal activation of T-lymphocytes and macrophages. The diagnosis of HLH can be established if there is a family history of HLH, or evidence of genetic defects, or if 5 of 8 clinicopathologic criteria are fulfilled. This case-control study aimed to examine the extent of hemophagocytosis on the bone marrow examination of patients fulfilling diagnostic criteria for HLH. Read More

View Article

Download full-text PDF

Source
June 2012
3 Reads

[Influence of a high-carbohydrate meal on taste perception].

Wiad Lek 2011 ;64(2):84-90

Katedra i Zakład Podstawowych Nauk Biomedycznych w Sosnowcu Slaskiego Uniwersytetu Medycznego w Katowicach.

Introduction: Taste sensitivity varies greatly in individuals and depends on many external and metabolic conditions.

Material And Methods: The studied group consisted of healthy, non-smoking 41 women and 40 men, aged 19-29. The volunteers were examined in fasting state and after a high-carbohydrate meal. Read More

View Article

Download full-text PDF

Source
December 2011
2 Reads

New records of helminth species and their hosts in Poland.

Authors:
Anna Okulewicz

Wiad Parazytol 2011 ;57(1):3-9

Department of Parasitology, Institute of Genetics and Microbiology of Wrocław University, 63 Przybyszewskiego Street, 51-148 Wrocław, Poland.

Information on species of parasitic helminths native to Poland is provided by the Pasozytnicze helminty Polski. Gatunki. Zywiciele. Read More

View Article

Download full-text PDF

Source
December 2011
2 Reads

[Polish Bank of Umbilical Stem Cord Blood].

Ginekol Pol 2010 Nov;81(11):877

Polski Bank Komórek Macierzystych, Warszawa.

View Article

Download full-text PDF

Source
November 2010
2 Reads

Acute erythroid leukemia.

Arch Pathol Lab Med 2010 Sep;134(9):1261-70

Department of Hematopathology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

Context: Acute erythroid leukemia (AEL) is an uncommon type of acute myeloid leukemia (AML), representing less than 5% of all cases. Acute erythroid leukemia is characterized by a predominant erythroid proliferation, and in the current World Health Organization (WHO) classification scheme there are 2 subtypes: erythroleukemia (erythroid/myeloid leukemia) and pure erythroid leukemia. Morphologic findings are most important for establishing the diagnosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1043/2009-0350-RA.1DOI Listing
September 2010
12 Reads

Recognition of Naegleriae ameba surface protein epitopes by anti-human CD45 antibodies.

Cytometry A 2010 Apr;77(4):305-9

Department of Biomedical Sciences, University of South Alabama, Mobile, Alabama 36688, USA.

Phagocytosis is a highly conserved mechanism exhibited by both free-living amebas and mammalian blood cells. Similarities demonstrated by either cell type during engulfment of the same bacterial species may imply analogous surface proteins involved in receptor-mediated endocytosis. The increased availability of anti-human leukocyte antibodies or clusters of differentiation (CD) markers used in conjunction with flow cytometric (FCM) and/or immunohistochemical (IHC) analysis provides investigators with a relatively easy method to screen different cell populations for comparable plasma membrane proteins. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cyto.a.20865DOI Listing
April 2010
1 Read

[Gustometry usefulness for the evaluation of taste sense efficiency. Part I. The range of taste substances concentrations and the result of gustometry examination].

Wiad Lek 2007 ;60(9-10):409-14

Z Katedry i Zakładu Podstawowych Nauk Biomedycznych w Sosnowcu Slaskiego Uniwersytetu Medycznego w Katowicach.

Unlabelled: There are various methods of taste substances application in gustometry examination. The Polish Committee of Standards (Polski Komitet Normalizacyjny--PKN) recommends the performance of sensitivity taste examinations with the use of method based on rinsing out the mouth with water solutions of taste substances (sip-and-spit method) at their growing concentrations. The aim of the present research was to assess the usefulness of taste substances dilutions, whose concentrations were consistent with guidelines of the PKN for the evaluation of the results of examination of sweet, salty and sour taste sensitivity. Read More

View Article

Download full-text PDF

Source
April 2008
5 Reads

Variations of anthropogenic CO2 in urban area deduced by radiocarbon concentration in modern tree rings.

J Environ Radioact 2008 Oct 12;99(10):1558-65. Epub 2008 Feb 12.

Center for Chronological Research, Nagoya University, Chikusa, Nagoya 464-8602, Japan.

Radiocarbon concentration in the atmosphere is significantly lower in areas where man-made emissions of carbon dioxide occur. This phenomenon is known as Suess effect, and is caused by the contamination of clean air with non-radioactive carbon from fossil fuel combustion. The effect is more strongly observed in industrial and densely populated urban areas. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jenvrad.2007.12.007DOI Listing
October 2008
2 Reads

[Analysis of the changes in the causes of blindness and significant vision loss among children and young adults born between 1974 and 2004].

Med Wieku Rozwoj 2007 Apr-Jun;11(2 Pt 2):193-216

Klinika Okulistyki, Instytut Pomnik-Centrum Zdrowia Dziecka, Warszawa.

Introduction: Visual impairment develops serious medical, psychological, social and economical problems. Thus, of most importance is improvement in prophylaxis, early diagnosis and treatment. THE AIM of this paper is to define the reasons of blindness and significant loss of vision in children and youths in Poland, and changes in them among children and youths under the age of 24, born between 1974-2004, with classification by age. Read More

View Article

Download full-text PDF

Source
August 2008
2 Reads

Heritability of hair whorl position on the forehead in Konik horses.

J Anim Breed Genet 2006 Dec;123(6):396-8

Department of Animal Behaviour, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Poland.

There are studies on the relationship between the position and shape of hair whorls on bovine forehead and phenotypic traits. According to anecdotal beliefs by horse users and handlers, temperamental traits may be related to the position of hair whorls in horses. No previous research on the mechanisms of inheritance of hair whorls has been performed, so the aim of the present study was to determine the heritability of the position of the hair whorl on the forehead of Konik horses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1439-0388.2006.00619.xDOI Listing
December 2006

[Assessment of blood flow in the middle cerebral artery and the umbilical artery in fetuses with umbilical venous pulsations].

Ginekol Pol 2006 Mar;77(3):190-6

Zakład USG Ginekologiczno-Poloiniczej, Instytut Centrum Zdrowia Matki Polski, Lódź.

Objectives: Umbilical venous pulsation is an important sign of hemodynamic compromise, especially during fetal heart failure and asphyxia.

Design: The aim of this study was to determine of the blow flow in the middle cerebral artery and the umbilical artery in fetuses with umbilical venous pulsations.

Materials And Methods: The investigation included 18 fetuses with signs of the intrauterine growth restriction and umbilical venous pulsations after 28th weeks of gestation. Read More

View Article

Download full-text PDF

Source
March 2006
3 Reads

Relationships between sexual behaviour, dominant follicle area, uterus ultrasonic image and pregnancy rate in mares of two breeds differing in reproductive efficiency.

Anim Reprod Sci 2005 Jul 22;87(3-4):283-93. Epub 2004 Dec 22.

Polish Academy of Sciences, Institute of Genetics and Animal Breeding, Jastrzebiec, 05-552 Wólka Kosowska, Poland.

Weak or equivocal expression of oestrous behaviour, related to different level of mares' reactivity, may cause problems in oestrus detection and thus influence the reproductive efficiency. The aim of the study was to test whether a breed characterised by low pregnancy rate and high emotional reactivity (Thoroughbreds) differs in oestrous behaviour from a primitive breed with higher reproductive efficiency (Koniks). Additionally, the follicle size was examined to determine how it influences the intensity of oestrus and uterine ultrasonic image and whether the pregnancy rate differs in relation to the intensity of oestrous behaviour and the size of the dominant follicle(s) area on day preceding ovulation in both breeds. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anireprosci.2004.11.007DOI Listing
July 2005
28 Reads

Pacinian corpuscle in human lymph node.

Lymphology 2005 Mar;38(1):18-9

Department of Pathology, University of South Alabama, Mobile, Alabama 36617, USA.

View Article

Download full-text PDF

Source

[Conservative treatment of ectopic pregnancy in a 27 years old patient with stage-Ia ovarian cancer after conservative surgical treatment and chemotherapy].

Med Wieku Rozwoj 2004 Apr-Jun;8(2 Pt 1):317-22

Klinika Ginekologii Operacyjnej i Endoskopowej, Instytut Centrum Zdrowia Matki Polski, Rzgowska 281/289, 93-338 Łódź, Poland.

We report a case of conservative treatment of ectopic pregnancy in a 27 years old patient, previously treated for ovarian cancer. Two years before she had surgery because of tumour in the left ovary. Ovarian cancer in stage la according to FIGO was confirmed. Read More

View Article

Download full-text PDF

Source
April 2005
2 Reads

Laïcité in hospitals.

Lancet 2004 Apr;363(9418):1401-2

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(04)16069-8DOI Listing
April 2004
5 Reads

The science behind forensic science.

Authors:
Joseph P Polski

Science 2004 Apr;304(5669):389

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.304.5669.389aDOI Listing

Lymph node infarction.

Arch Pathol Lab Med 2003 Aug;127(8):922

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1043/1543-2165(2003)127<922a:LNI>2.0.CO;2DOI Listing
August 2003
2 Reads

Acute megakaryoblastic leukemia after transient myeloproliferative disorder with clonal karyotype evolution in a phenotypically normal neonate.

J Pediatr Hematol Oncol 2002 Jan;24(1):50-4

Department of Pathology, University of South Alabama College of Medicine, Mobile, USA.

We report a case of transient myeloproliferative disorder (TMD) in a neonate without features of Down syndrome (DS) with clonal karyotype evolution, after apparent spontaneous resolution of TMD, but eventually progressing to acute megakaryoblastic leukemia (AMKL). The patient had petechiae, thrombocytopenia, and blastemia. Trisomy 21 with a satellited Y chromosome (Yqs) was found in proliferating blasts. Read More

View Article

Download full-text PDF

Source
January 2002
2 Reads