Search Our Scientific Publications & Authors

Mol Med Rep 2021 Aug 10;24(2). Epub 2021 Jun 10.

Department of Microbiology and Parasitology, China Medical University, Shenyang, Liaoning 110001, P.R. China.

(MP) is a common pathogen that can cause respiratory infections. MP pneumonia (MPP) leads to numerous complications, including lung injury and even death. The present study aimed to investigate the protective effects of Baicalin treatment on MP infection‑induced lung injury and the molecular mechanism underlying these effects. Read More

J Dairy Sci 2021 Jun 4. Epub 2021 Jun 4.

Department of Population Medicine and Diagnostic Sciences, Cornell University, Ithaca, NY 14853-6401. Electronic address:

The objective of this randomized clinical study was to compare the effect of 2 antimicrobial interventions, tildipirosin or florfenicol + flunixin meglumine, used for treatment of pneumonia and extralabel treatment for otitis on health parameters and upper respiratory tract (URT) microbiota of preweaned Holstein calves. Housed preweaned Holstein heifers diagnosed with either otitis or pneumonia were assigned into 1 of 2 treatment groups, receiving a single subcutaneous injection of either 4 mg/kg of tildipirosin (TLD; n = 444) or 40 mg/kg of florfenicol combined with 2.2 mg/kg of a nonsteroidal anti-inflammatory, flunixin meglumine (FLF; n = 442). Read More

J Int Med Res 2021 Jun;49(6):3000605211016376

Department of Respiratory Medicine, Children's Hospital of Nanjing Medical University, Nanjing, China.

Objective: To investigate the prevalence of mutations in domain V of (MP) 23S ribosomal RNA (rRNA) and the clinical characteristics of pediatric MP pneumonia (MPP) in Nanjing, China.

Methods: Domain V of 23S rRNA was sequenced in MP strains collected from children diagnosed with MPP in Nanjing. Clinical and laboratory data were obtained. Read More

Sci Rep 2021 Jun 2;11(1):11571. Epub 2021 Jun 2.

Department of Microbiology, Immunology and Molecular Genetics, University of Texas Health San Antonio, San Antonio, TX, 78229, USA.

Mycoplasma pneumoniae is the leading cause of bacterial community-acquired pneumonia among hospitalized children in the United States. It is also responsible for a spectrum of other respiratory tract disorders and extrapulmonary manifestations in children and adults. The main virulence factor of M. Read More

Vaccines (Basel) 2021 May 24;9(6). Epub 2021 May 24.

The Oaks, Nutshell Lane, Farnham, Surrey GU9 0HG, UK.

Two of the most important diseases of cattle are caused by mycoplasmas. is a world-wide bovine pathogen that can cause pneumonia, mastitis and arthritis. It has now spread to most, if not all, cattle-rearing countries. Read More

Animals (Basel) 2021 May 20;11(5). Epub 2021 May 20.

Ruminant Health Research Group, Department of Animal Health, Faculty of Veterinary Sciences, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, 30100 Murcia, Spain.

Bovine respiratory disease (BRD) is an important viral and/or bacterial disease that mainly affects feedlot calves. The involvement of in BRD can lead to chronic pneumonia poorly responsive to antimicrobial treatment. Caseonecrotic bronchopneumonia is a pulmonary lesion typically associated with . Read More

Vaccines (Basel) 2021 May 3;9(5). Epub 2021 May 3.

Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Korea.

The present field trial compared two combined vaccines of porcine circovirus type 2 (PCV2) and , each administered in herd with subclinical PCV2d infection and enzootic pneumonia. One vaccine was a bivalent containing PCV2a and and the other was a trivalent vaccine containing PCV2a and 2b (PCV2a/b), and . The defining difference between these two vaccines was the inclusion or absence of PCV2b antigen. Read More

Biomed Res Int 2021 14;2021:6646664. Epub 2021 Apr 14.

Tibet Agriculture and Animal Husbandry College, Linzhi 860000, China.

(. ) is one of the most important pneumonia pathogens in yaks. It may result in more economic losses due to the cold and anoxia condition at Qinghai Tibetan plateau. Read More

Int Med Case Rep J 2021 20;14:339-342. Epub 2021 May 20.

Department of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Background: Miller Fisher syndrome (MFS), a triad of ophthalmoplegia, areflexia and ataxia, is one of the regional variants of Guillain-Barré syndrome (GBS) that might account for a quarter of all cases of GBS, especially in Asian countries. There is history of an antecedent upper respiratory tract infection in up to two thirds of MFS cases. However, association of MFS in adults and pneumonia is rarely reported and in those cases causative pathogen was . Read More

J Int Med Res 2021 May;49(5):3000605211015579

Children's Hospital of Wujiang District, Suzhou, China.

Objective: To determine the risk factors for delayed radiographic resolution in children with refractory pneumonia (RMPP) and explore the most suitable time for interventional bronchoscopy.

Methods: This retrospective study involved 142 children with RMPP who were admitted to our hospital from 1 January 2015 to 31 December 2017. They were divided into a common resolution group and a delayed resolution group based on their chest radiograph series. Read More

Zhonghua Yu Fang Yi Xue Za Zhi 2021 May;55(5):660-666

Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100070, China Department of Pediatrics, China-Japan Friendship Hospital, Beijing 100029, China.

This study was aimed to analyze the untargeted metabolomics of serum samples from children with mycoplasma pneumonia in a hospital in Beijing. A total of 50 children with mycoplasma pneumonia as the case group were recruited from Department of Pediatrics, China-Japan Friendship Hospital in Beijing from January 2019 to February 2020, and meanwhile 50 age-and gender-matched heathy children were selected and formed the control group. 2 ml venous fasting blood samples was collected from all children. Read More

J Coll Physicians Surg Pak 2021 May;30(5):605-607

Department of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, China.

The aim of this study was to investigate the role of TFH cells and interleukin (IL)-21 in the pathogenesis of childhood Mycoplasma pneumoniae pneumonia (MPP). It was a retrospective study carried out at Yantai Yuhuangding Hospital, China from July 2016 to June 2019. It comprised 46 healthy control (HC) children and 106 pediatric patients, including 60 children with general MPP (GMPP) and 46 children with refractory MPP (RMPP). Read More

Vet Microbiol 2021 Jul 15;258:109123. Epub 2021 May 15.

São Paulo State University, School of Agricultural and Veterinarian Sciences, Jaboticabal, São Paulo, Brazil. Electronic address:

Infections with Mycoplasma hyopneumoniae (Mhyo), Mycoplasma hyorhinis (Mhr) and Mycoplasma flocculare (Mfloc) are common in swine. However, the degree of co-infections and the correlations between these mycoplasma co-infection and the severity of macroscopic lung consolidation lesions (MLCL) have not yet been explored in Brazil.The objectives were to quantify Mhyo, Mhr, and Mfloc in MLCL of slaughter pigs in Brazil, and to assess correlations with the degree of MLCL in slaughter pigs. Read More

Vet Med Sci 2021 May 22. Epub 2021 May 22.

State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.

Vaccination with inactivated bacterin is the most popular and practical measure to control enzootic pneumonia. After immunisation with inactivated bacterin, Mycoplasma hyopneumoniae colonised on the respiratory tract and lung stimulates the humoural immune responses and produces IgG and IgA antibodies. ELISA is a widely used serological method to detect M. Read More

Zhongguo Dang Dai Er Ke Za Zhi 2021 May;23(5):471-474

Department of Pediatrics, Guangdong Women and Children's Hospital, Guangzhou 510010, China.

Objective: To evaluate the value of chitinase-like protein YKL-40 in bronchoalveolar lavage fluid (BALF) for predicting refractory pneumonia (RMPP) in children.

Methods: A total of 50 children with common pneumonia (MPP) and 22 children with RMPP were enrolled. The two groups were compared in terms of clinical features, laboratory examination results, imaging findings, and YKL-40 levels in BALF. Read More

J Family Med Prim Care 2021 Jan 30;10(1):93-101. Epub 2021 Jan 30.

Professor, Department of Pediatrics, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

Cutaneous manifestation of COVID 19 in children has not yet been reviewed systematically. Hence, this review gives the clinicians a future direction to be vigilant for skin presentations during pandemics. The Pubmed database used for literature search with keywords COVID 19, children, and skin in different combinations. Read More

Emerg Infect Dis 2021 Jun;27(6):1588-1597

Emergence of macrolide-resistant Mycoplasma pneumoniae (MRMp) challenges empiric macrolide therapy. Our goal was to determine MRMp rates and define characteristics of children infected with macrolide-sensitive M. pneumoniae (MSMp) versus MRMp in Ohio, USA. Read More

Transl Pediatr 2021 Apr;10(4):990-997

Department of Pediatric Pulmonology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Background: Respiratory tract infection (RTIs) is one of common diseases among the children. In recent years, the incidence of () infection rate has been increasing, which cause respiratory tract infection. This study sought to analyze the epidemiological characteristics of hospitalized children with RTIs to provide a theoretical basis for clinical diagnosis and treatments in Chengdu, China. Read More

Mediterr J Hematol Infect Dis 2021 1;13(1):e2021037. Epub 2021 May 1.

Department of Laboratory, Maternal and Child Health Hospital of Hubei Province, China.

BMC Pulm Med 2021 May 18;21(1):168. Epub 2021 May 18.

Department of Pediatrics, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, 150, Seongan-ro, Gangdong-gu, Seoul, 05355, Republic of Korea.

Objective: To identify patients with Mycoplasma pneumoniae pneumonia (MPP) with a risk of prolonged fever while on macrolides.

Methods: A retrospective study was performed with 716 children admitted for MPP. Refractory MPP (RMPP-3) was defined as fever persisting for > 72 h without improvement in clinical and radiologic findings after macrolide antibiotics (RMPP-3) or when fever persisted for > 120 h (RMPP-5) without improvement in clinical and radiologic findings. Read More

Porcine Health Manag 2021 May 17;7(1):37. Epub 2021 May 17.

Norwegian Pig Health Service, Animalia AS, P.O. Box 396, Økern, 0513, Oslo, Norway.

Background: Mycoplasma hyopneumoniae (Mhyo) is the causative agent of enzootic pneumonia in pigs which adversely affects animal health and welfare, in addition to causing considerable economical losses. This paper presents the implementation of the national Mhyo eradication program in Norway, the subsequent population wide surveillance and documentation on the current freedom from Mhyo in the Norwegian pig population. In 1994, the Board of The Norwegian Pig Health Service decided on conducting a national surveillance and eradication program for Mhyo. Read More

JAAD Case Rep 2021 May 16;11:139-143. Epub 2021 Mar 16.

Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

J Microbiol Methods 2021 Jul 13;186:106239. Epub 2021 May 13.

Tropical Medicine Institute "Pedro Kourí" (IPK), Center for Research, Diagnosis and Reference, Avenida Novia del Mediodía, KM 6 1/2, La Lisa, La Habana CP. 11400, Cuba.

We used multi-locus variable-number of tandem repeat analysis (MLVA), p1, multi-locus sequence (MLS) and single nucleotide polymorphisms (SNP) typing to characterize a collection of Mycoplasma pneumoniae strains from Cuba and Germany. Among 67 strains, 5 p1, 7 MLVA, 11 MLS, and 11 SNP types were obtained. Read More

Vet Microbiol 2021 Jul 4;258:109100. Epub 2021 May 4.

Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul, 08826, Republic of Korea. Electronic address:

The purpose of this experimental study was to evaluate the efficacy of a new trivalent vaccine containing porcine circovirus types 2a/b (PCV2a/b) and Mycoplasma hyopneumoniae. Pigs were administered the vaccine intramuscularly as either at 3 and 24 days of age with 1.0 mL or at 21 days of age with 2. Read More

Intern Emerg Med 2021 May 13. Epub 2021 May 13.

Department of Primary Care and Medical Education, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

Community-acquired pneumonia (CAP) is a common illness that can lead to mortality. β-lactams are ineffective against atypical pathogen including Mycoplasma pneumoniae. We used molecular examinations to develop a decision tree to predict atypical pathogens with CAP and to examine the prevalence of macrolide resistance in Mycoplasma pneumoniae. Read More

Clin Lab 2021 May;67(5)

Background: Mean platelet volume (MPV) is a parameter of platelet size and activity. Research on MPV in Mycoplasma pneumoniae infection is not reported.

Methods: This study reviewed whether there was a difference in the MPV in the results of M. Read More

Front Microbiol 2021 22;12:518791. Epub 2021 Apr 22.

Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, United States.

is the causative agent of enzootic pneumonia, a world-wide problem in the pig industry. This disease is characterized by a dry, non-productive cough, labored breathing, and pneumonia. Despite years of research, vaccines are marginally effective, and none fully protect pigs in a production environment. Read More

Front Pediatr 2021 20;9:651487. Epub 2021 Apr 20.

Department of Neonatology, National Clinical Research Center for Child Health, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Inflammatory response, oxidative stress, and immunologic mechanism are involved in the pathogenesis of pneumonia (MPP). However, the role of immune system of pediatric interstitial pneumonia due to infections remains poorly understood. The aim of this study was to analyze the immunologic features of pediatric interstitial pneumonia due to . Read More

J Clin Microbiol 2021 May 5. Epub 2021 May 5.

Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada

is a significant pathogen of feedlot cattle, responsible for chronic pneumonia and polyarthritis syndrome (CPPS). isolates ( = 129) were used to compare four methods of phylogenetic analysis, and to determine if the isolates' genotypes were associated to phenotypes. Metadata included the health status of the animal from which an isolate was derived (healthy, diseased, dead); anatomical location (nasopharynx, lung, joint); feedlot; and production year (2006 to 2018). Read More

Braz J Microbiol 2021 May 3. Epub 2021 May 3.

Laboratory of Animal Virology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Londrina, Paraná, Brazil.

This is the first study conducted in Paraná, Brazil, to investigate Mycoplasma hyopneumoniae (Mhyo) infection in free-living wild boars. Eighty-eight wild boars were managed by authorized controllers between 2017 and 2019 in the state of Paraná in southern Brazil. Management georeferencing, sex, and weight were recorded for each animal. Read More