144,227 results match your criteria Pneumonia Mycoplasma


Efficacy and safety of partial splenic embolization for hypersplenism in pre- and post-liver transplant patients: A 16-year comparative analysis.

Clin Imaging 2018 Nov 27;54:71-77. Epub 2018 Nov 27.

Department of Radiology, Division of Vascular and Interventional Radiology, Columbia University Medical Center, 177 Fort Washington Ave, Milstein Hospital - 4 Hudson North, New York, NY 10032, United States of America.

Purpose: To report the effect of partial splenic embolization (PSE) on hematological indices and the procedure's safety in pre- and post-liver transplant (LT) patients.

Materials And Methods: A single-center retrospective study evaluating all patients who underwent PSE over a 16-year period was performed. Inclusion criteria were splenomegaly confirmed by imaging and at least one of the following cytopenias: hemoglobin ≤10 g/dL, WBC count ≤1500 μL, or platelet count ≤100,000 μL. Read More

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November 2018
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Acute Eosinophilic Pneumonia due to Piperacillin/Tazobactam.

Ann Allergy Asthma Immunol 2018 Dec 12. Epub 2018 Dec 12.

Allergy Department Hospital Universitario 12 de Octubre, Avenida de Córdoba s/n, Postal code 28041 , Madrid, Spain.

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December 2018

Cost of oropharyngeal dysphagia after stroke: protocol for a systematic review.

BMJ Open 2018 Dec 14;8(12):e022775. Epub 2018 Dec 14.

Centro de Investigación Biomédica en Red de enfermedades hepáticas y digestivas (CIBERehd), Instituto de Salud Carlos III, Barcelona, Spain.

Introduction: Oropharyngeal dysphagia (OD) is a major disorder following stroke. OD can produce alterations in both the efficacy and safety of deglutition and may result in malnutrition, dehydration, frailty, respiratory infections and pneumonia. These complications can be avoided by early detection and treatment of OD in poststroke patients, and hospital stays, medication and mortality rates can be reduced. Read More

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December 2018

Postdischarge Mortality Prediction in Sub-Saharan Africa.

Pediatrics 2018 Dec 14. Epub 2018 Dec 14.

Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique;

Background: Although the burden of postdischarge mortality (PDM) in low-income settings appears to be significant, no clear recommendations have been proposed in relation to follow-up care after hospitalization. We aimed to determine the burden of pediatric PDM and develop predictive models to identify children who are at risk for dying after discharge.

Methods: Deaths after hospital discharge among children aged <15 years in the last 17 years were reviewed in an area under demographic and morbidity surveillance in Southern Mozambique. Read More

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December 2018

Smaller erector spinae muscle size is associated with inability to recover activities of daily living after pneumonia treatment.

Respir Investig 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address:

Background: Elderly patients who are hospitalized due to pneumonia experience deterioration of their activities of daily living (ADL) during this period; in some cases, this loss of ADL is not recovered at the end of antibiotic treatment. In this study, we examined whether erector spinae muscle cross-sectional area (ESMCSA) measured by computed tomography (CT) could predict a low level of ADL at the end of antibiotic treatment for pneumonia.

Methods: Eighty patients (mean age 74. Read More

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December 2018

Clinical, immunological and bacteriological characteristics of H7N9 patients nosocomially co-infected by Acinetobacter Baumannii: a case control study.

BMC Infect Dis 2018 Dec 14;18(1):664. Epub 2018 Dec 14.

Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, 518112, China.

Background: Bacterial co-infection of patients suffering from influenza pneumonia is a key element that increases morbidity and mortality. The occurrence of Acinetobacter baumannii co-infection in patients with avian influenza A (H7N9) virus infection has been described as one of the most prevalent bacterial co-infections. However, the clinical and laboratory features of this entity of H7N9 and A. Read More

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December 2018

Radiologic finding of bronchial asthma.

Nihon Rinsho 2016 Oct;74(10):1634-1639

High-resolution computed tomography (HRCT) scan is a noninvasive technique that might be valuable for evaluating bronchial wall thickening and bronchiectasis as a result of chronic inflammation in patients with severe asthma. HRCT is also useful to diagnose the complications of asthma such as pulmonary emphysema and chronic eosinophilic pneumonia. In addition, HRCT will be able to demonstrate the tracheobronchial and parenchymal abnormality dis- tinctly, with the result that it will be helpful for making differential diagnosis in the patients with wheeze, including allergic bronchopulmonary aspergillosis, eosinophilic granulomatosis with polyangiitis, bronchial tuberculosis and tracheal tumor. Read More

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October 2016

Avian influenza.

Authors:
Shoji Kawachi

Nihon Rinsho 2016 Dec;74(12):1979-1983

Highly pathogenic avian influenza A (H5N1) came to the attention of the international sci- entific community for the first time in 1997 at Hong Kong. The current global spread of hu- man infection by this subtype started in 2003. Since then, many clinical case reports on H5N1 have been reported. Read More

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December 2016

SARS, MERS and coronavirus infections.

Authors:
Akihiko Kawana

Nihon Rinsho 2016 Dec;74(12):1967-1972

The human coronavirus (HCoV) contains HCoV-229E, HCoV-NL63, HCoV-OC43, HCoV- HKU1, SARS-CoV and MERS-CoV. HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1 are pathogens of common cold. During 2002-2003, a new coronavirus, the SARS-CoV, was found to be the cause of an acute, severe frequently fatal respiratory disease with prominent systemic symptoms (severe acute respiratory syndrome). Read More

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December 2016

Ventilator-associated pneumonia: The central role of transcolonization.

J Crit Care 2018 Dec 6;50:155-161. Epub 2018 Dec 6.

Medical and Surgical Intensive Care Unit, Groupe Hospitalier Paris Saint Joseph, Paris, France; Endotoxins, Structures and Host Response, Department of Microbiology, Institute for Integrative Biology of the Cell, UMR 9891 CNRS-CEA-Paris Saclay University, 98190 Gif-sur-Yvette, France. Electronic address:

Ventilator-associated pneumonia remain frequent and serious diseases since they are associated with considerable crude mortality. Pathophysiology is centered on modifications of regional bacterial flora, especially tracheobronchial tree and oropharyngeal sphere. Bacterial migration from an anatomical area to another seems to be the main explanation of these alterations which are called "transcolonization". Read More

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December 2018

Normal axillary thickness thresholds as a metric for nutritional status of children.

Clin Imaging 2018 Dec 1;54:57-62. Epub 2018 Dec 1.

Department of Radiology, University of Michigan Medical School, 3208C Medical Sciences Building 1, B1D502, Ann Arbor, MI 48109-5030, United States of America. Electronic address:

Introduction: Childhood pneumonia is a major cause of death in the 3rd world, and undernourishment increases the severity of the condition. We considered axillary thickness as a simple measurement to evaluate nutritional status that can be performed simultaneously with lung ultrasound. Our goal was to determine the distribution of axillary thickness in a cohort of children to determine a threshold for malnutrition. Read More

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December 2018
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Etiology and epidemiology of community-acquired pneumonia in adults requiring hospital admission: a prospective study in rural Central Philippines.

Int J Infect Dis 2018 Dec 11. Epub 2018 Dec 11.

Department of Virology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Japan980-8575; Collaborating Research Center for Emerging and Reemerging Infectious Diseases, 9002 Research Drive, Filinvest Corporate City, Alabang, Muntinlupa City, Metro Manila, Philippines 1781.

Background: Community-acquired pneumonia (CAP) is a common cause of morbidity and mortality among adults worldwide. However, the distribution of etiology of CAP varies from one country to another with limited data from rural areas.

Methods: A prospective hospital-based study on adult CAP was conducted in Leyte, Central Philippines from May 2010 to May 2012. Read More

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December 2018

Induction of protective immunity by recombinant peptidoglycan associated lipoprotein (rPAL) protein of Legionella pneumophila in a BALB/c mouse model.

Microb Pathog 2018 Dec 11. Epub 2018 Dec 11.

Department of Microbiology, Faculty of Advanced Sciences, Medical Sciences University Islamic Azad, Tehran, Iran.

Legionella pneumophila causes a severe form of pneumonia known as Legionnaires' disease especially in patients with impaired cellular immune response. In order to prevent the disease, immunogenicity and the level of the induction of protective immunity from the recombinant peptidoglycan-associated lipoprotein (rPAL) against Legionella pneumophila in BALB/c mice was examined. Mice immunized with (rPAL) rapidly increased an antibody response in serum and also displayed a strong activation of both innate and adaptive cell-mediated immunity as determined by antigen-specific splenocyte proliferation, an early production of pro-inflammatory cytokines in the serum and in the splenocyte cultures. Read More

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December 2018
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Biologically synthesized copper oxide nanoparticles enhanced intracellular damage in ciprofloxacin resistant ESBL producing bacteria.

Microb Pathog 2018 Dec 11. Epub 2018 Dec 11.

School of Chemistry & Chemical Engineering, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Anhui University, Hefei, Anhui 230601, PR China. Electronic address:

Copper oxide nanoparticles (CuO NPs) were synthesized biologically using leaf extract of Camilla japonica. The typical UV-visible spectral peak of CuO NPs was observed at a wavelength of ∼290 nm, which confirmed their successful synthesis. From scanning electron microscope (SEM) and transmission electron microscope (TEM) analyses, the synthesized CuO NPs were found to possess spherical shape. Read More

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December 2018

Maternal vaccination with a novel chimeric glycoprotein formulated with a polymer-based adjuvant provides protection from human parainfluenza virus type 3 in newborn lambs.

Antiviral Res 2018 Dec 11. Epub 2018 Dec 11.

VIDO-InterVac, University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada; Microbiology & Immunology, University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada. Electronic address:

Human parainfluenza virus 3 (PIV3) and respiratory syncytial virus (RSV) are major causative agents of serious respiratory tract illness in newborns and infants. Maternal vaccination could be a promising approach to provide immediate protection against severe PIV3 and RSV infection in young infants. Previously, we demonstrated that maternal immunization with a subunit vaccine consisting of the RSV fusion (F) protein formulated with TriAdj, an adjuvant consisting of poly(I:C), immune defense regulatory peptide and polyphosphazene, protects newborn lambs from RSV. Read More

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December 2018

[The clinical laboratory characteristic of primary acute cytomegalovirus infection in non-immunocompromised adult patients].

Klin Lab Diagn 2018 ;63(1):51-54

The state budget institution of health care "The clinical center of prevention and struggle with AIDS" of the Minzdrav of the Krasnodar kraii, 350015, Krasnodar, Russia.

The purpose of study is the clinical laboratory characteristic of acquired acute cytomegalovirus infection in nonimmunocompromised adult patients. The sampling included 75 patients with acquired acute cytomegalovirus infection admitted to the specialized clinical infection hospital of the Minzdrav of the Krasnodar kraii. The verifcation of diagnosis was implemented using serological tests and polymerase chain reaction. Read More

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January 2018
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Pneumonia Risk in Urgently Intubated Burn Patients.

Isr Med Assoc J 2018 Dec;20(12):737-740

Department of Plastic and Reconstructive Surgery, Rambam Health Care Campus, affiliated with Technion-Israel Institute of Technology, Haifa, Israel.

Background: Pneumonia is a major cause of morbidity and mortality in burn patients with inhalation injuries. An increased risk of pneumonia has been demonstrated in trauma and burn patients urgently intubated in the field vs. emergency departments (EDs). Read More

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December 2018

Serum Cryptococcal Antigen Confirmed Pulmonary Cryptococcosis in an Immune-competent Adult Firstly Misdiagnosed of Tuberculosis from a Lung Biopsy: a Case Report and Literature Review.

Clin Lab 2018 Oct;64(11)

Background: Cryptococcal pneumonia is an uncommon lesion in immune-competent adults. Histological evidence of Cryptococcus neoformans is a gold criterion for diagnosis. Here we report a case firstly misdiagnosed as tuberculosis from a lung biopsy. Read More

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October 2018

Prospective study of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia.

Pediatr Pulmonol 2018 Dec 14. Epub 2018 Dec 14.

Department of Pediatrics, Section of Neonatology, Cumming School of Medicine, Calgary, Alberta, Canada.

Objective: To evaluate the prevalence, risk factors, and optimal timing of echocardiogram for pulmonary hypertension (PH) in infants with bronchopulmonary dysplasia (BPD).

Design: In this prospective study, infants with gestational age (GA) <30 weeks admitted to a tertiary NICU between July 2015 and June 2017 who required positive pressure ventilation or oxygen therapy at ≥28 days of life were evaluated with serial echocardiograms at study enrollment (4-6 weeks of age), 32 weeks (only for ≤25 weeks), 36, and 40 weeks post-menstrual age (PMA) for PH.

Results: Of 126 infants (mean birth weight 858 ± 221 g; mean GA 26. Read More

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December 2018
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Respiratory morbidity in young people surviving cancer: Population-based study of hospital admissions, treatment-related risk factors and subsequent mortality.

Int J Cancer 2018 Dec 14. Epub 2018 Dec 14.

Clinical and Population Science Department, School of Medicine, University of Leeds, Leeds, UK.

Respiratory diseases are a major cause of late morbidity and mortality amongst childhood cancer survivors. This population-based study investigates respiratory hospital admissions in long-term survivors of cancers diagnosed in young people to identify specific respiratory morbidities, treatment-related risks and their relationship to subsequent morbidity and mortality. Population-based cancer registrations in Yorkshire, England, diagnosed between 1990 and 2011 aged 0-29 years, were linked to inpatient Hospital Episode Statistics (HES) for admissions up to 2017. Read More

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December 2018

Immunotherapeutic effects of recombinant adenovirus encoding interleukin 12 in experimental pulmonary tuberculosis.

Scand J Immunol 2018 Dec 13:e12743. Epub 2018 Dec 13.

Sección de Patología Experimental, Departamento de Patología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, México.

High dose of Mycobacterium tuberculosis (Mtb) strain H37Rv administered by intratracheal injection in BALB/c mice induce progressive tuberculosis (TB). In this model during the first month there is a temporal control of bacillary growth, in co-existence with macrophage activation, granuloma formation and Th-1 response. Then, bacterial proliferation recommences, accompanied by progressive pneumonia and decreasing expression of protective cytokines (IFN-γ, TNF-α). Read More

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December 2018

Etiology of acute viral respiratory infections common in Pakistan: A review.

Rev Med Virol 2018 Dec 12:e2024. Epub 2018 Dec 12.

Department of Bioinformatics and Biotechnology, International Islamic University, Islamabad, Pakistan.

Respiratory infections, especially those of the lower respiratory tract, remain a foremost cause of mortality and morbidity of children greater than 5 years in developing countries including Pakistan. Ignoring these acute-level infections may lead to complications. Particularly in Pakistan, respiratory infections account for 20% to 30% of all deaths of children. Read More

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December 2018

Polydatin suppresses the development of lung inflammation and fibrosis by inhibiting activation of the NACHT domain-, leucine-rich repeat-, and pyd-containing protein 3 inflammasome and the nuclear factor-κB pathway after Mycoplasma pneumoniae infection.

J Cell Biochem 2018 Dec 12. Epub 2018 Dec 12.

Centre for Reproductive Medicine and Department of Laboratory Medicine, First Affiliated Hospital, Second Military Medical University, Shanghai, China.

Mycoplasma pneumoniae (MP) can infect both the upper and lower respiratory tracts. Polydatin (PD), a traditional Chinese medicine, is known to have anti-inflammation and antifibrosis properties. However, the protective effects of PD against MP pneumonia (MPP) remain unclear. Read More

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December 2018

A case of pan-resistant burkholderia cepacia complex bacteraemic pneumonia, after lung transplantation treated with a targeted combination therapy.

Transpl Infect Dis 2018 Dec 12:e13034. Epub 2018 Dec 12.

Unidad de Cuidados Intensivos. Hospital Universitario Virgen Macarena, Sevilla.

We describe a case of one patient with cystic fibrosis who developed a pan-resistant Burkholderia Cepacia Complex rapidly progressive bacteraemic pneunonia, following bilateral lung transplantation. Patient was treated with a targeted combination antibiotic therapy (meropenem plus ceftazidime/avibactam plus high doses of nebulized colistimethate sodium). The disease evolution was complicated by multiple organ system dysfunction. Read More

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December 2018

Atypical actinobacillosis affecting hind limbs and lungs in a single beef cattle herd.

J Vet Intern Med 2018 Dec 12. Epub 2018 Dec 12.

Clinic for Ruminants, Nantes, France.

Actinobacillosis usually is a sporadic infection that affects the tongue in cattle ("wooden tongue") with possible spread to the digestive tract. Two 4-year-old Rouge-des-Prés cows from a single French beef herd were referred for chronic (2-6 months) swelling and cutaneous nodules in the distal hind limbs. In addition to cutaneous signs, physical examination disclosed cachexia, lameness, lymphadenitis of the hind limbs, and pneumonia in both cows. Read More

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December 2018
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Effect of educational environments on nursing faculty members' perceptions regarding oral care.

Jpn J Nurs Sci 2018 Dec 11. Epub 2018 Dec 11.

Section of Geriatric Dentistry, Department of General Dentistry, Fukuoka Dental College, Fukuoka, Japan.

Aim: To investigate nursing faculty members' perceptions of oral care and to identify the effects of an educational environment on their perceptions.

Methods: A cross-sectional questionnaire regarding oral care was conducted at eight nursing schools in Japan. A total of 156 (71. Read More

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December 2018

Can Robotic-Assisted Surgery Overcome the Risk of Mortality in Cardiac Reoperation?

Innovations (Phila) 2018 Nov/Dec;13(6):438-444

Department of Surgery, University of Maryland School of Medicine, Baltimore, MD USA.

Objective: A robotic-assisted approach potentially has many advantages for cardiac reoperation, which include sternum-sparing and three-dimensional visualization leading to precise adhesiolysis and excellent exposure in a limited field.

Methods: We retrospectively reviewed our patients undergoing robotic cardiac reoperation (redo group) from July 2013 to April 2017 at our institution and compared with our patients undergoing standard robotic surgery (nonredo group). In the reoperative cases, a thoracoscope was inserted through a 5-mm port placed away from the previous scar. Read More

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December 2018

Clinical outcomes of radiation therapy for clinical T4b oesophageal cancer with airway invasion.

Radiat Oncol 2018 Dec 14;13(1):245. Epub 2018 Dec 14.

Department of Thoracic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Background: Oesophageal cancer with airway invasion presents a challenge for therapy and often has serious complications. We analysed the clinical outcomes of radiation therapy (RT) in patients with clinical T4b oesophageal cancer with airway invasion.

Methods: We retrospectively reviewed the medical records of 73 patients with oesophageal cancer who had clinical T4 disease and who received RT between January 1994 and June 2017. Read More

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December 2018

The Use of Procalcitonin for Prediction of Pulmonary Bacterial Coinfection in Children With Respiratory Failure Associated With Viral Bronchiolitis.

Clin Pediatr (Phila) 2018 Dec 14:9922818816432. Epub 2018 Dec 14.

1 University of Oklahoma Health Science Center, Oklahoma City, OK, USA.

Objectives: Viral bronchiolitis is a frequent cause of pediatric hospitalization and respiratory failure. Procalcitonin (PCT) is a biomarker used to identify serious bacterial infection and can distinguish bacterial and viral infections. Concomitant bacterial pneumonia is not rare in viral bronchiolitis and can lead to a worse clinical course. Read More

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December 2018

Arterial repair after bare-metal stent implantation in peripheral arteries is delayed compared to that in coronary arteries: A case report of pathological evaluation.

J Cardiol Cases 2016 Sep 14;14(3):74-77. Epub 2016 May 14.

Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan.

Despite widespread use of endovascular therapy with bare-metal stent (BMS) implantation in patients with peripheral artery disease (PAD), arterial healing has not been well examined in this setting. An 84-year-old man with PAD received BMS implantation at the right external iliac artery (EIA, Epic 8.0 mm × 100 mm) and superficial femoral artery (SFA, SMART Control 8. Read More

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September 2016

Pneumococcal endocarditis complicating meningitis and arthritis in a previously healthy woman: A case report.

J Cardiol Cases 2015 Mar 19;11(3):96-99. Epub 2014 Dec 19.

Division of Cardiology, Shimane University Faculty of Medicine, Shimane-ken, Japan.

is the most common cause of community-acquired bacterial meningitis in adults. Pneumococcal endocarditis coexisting with meningitis is rare, especially in healthy individuals. A 66-year-old woman was admitted with pneumococcal bacteremia, meningitis, and arthritis. Read More

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Biodegradation of Pollutants in Waste Water from Pharmaceutical, Textile and Local Dye Effluent in Lagos, Nigeria.

J Health Pollut 2016 Dec 19;6(12):34-42. Epub 2016 Dec 19.

Environmental Biology Unit, Department of Biological Science, Yaba College of Technology, Yaba, Lagos, Nigeria.

Background: Discharged effluents from industry have been responsible for the deterioration of the aquatic environment in many parts of the world, especially in developing countries. Increasing industrialization and urbanization have resulted in the discharge of large amounts of waste into the environment, resulting in high pollution loads. Utilization of microbes such as fungi and bacteria have been used for pollution degradation. Read More

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December 2016
2 Reads

Recurrent takotsubo cardiomyopathy with variant forms of left ventricular dysfunction.

J Cardiol Cases 2010 Aug 20;2(1):e37-e40. Epub 2010 Feb 20.

Ohtaki Hearts Clinic, Bunkyo-ku, Tokyo, Japan.

A 78-year-old man presented to our emergency department with dyspnea. The patient was diagnosed as having pneumonia from the chest X-ray which depicted mass-like opacity in the left lower lobe. On the 5th hospital day, electrocardiography showed giant negative T waves in pericardial leads and echocardiography demonstrated left ventricular apical akinesis and basal hyperkinesis. Read More

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The bacteriology in adult patients with pneumonia and parapneumonic effusions: increased yield with DNA sequencing method.

Eur J Clin Microbiol Infect Dis 2018 Dec 13. Epub 2018 Dec 13.

Department of Medicine, Solna, Infectious Diseases Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

The aim of this study was to use a 16S rDNA sequencing method in combination with conventional culture in patients with parapneumonic effusions (PPE) to evaluate the methods, study the microbiological spectrum, and examine the presence of bacteria within the different stages of PPE. Adults with community-acquired pneumonia (CAP) and PPE (n = 197) admitted to the Departments of Infectious Diseases at four hospitals in Stockholm County during 2011-2014 were prospectively studied. All patients underwent thoracentesis. Read More

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December 2018

Chronic obstructive pulmonary disease is an independent predictor for 30-day readmissions following 1- to 2-level posterior lumbar fusions.

J Spine Surg 2018 Sep;4(3):553-559

Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

Background: Chronic obstructive pulmonary disease (COPD) is a common cause of morbidity and mortality worldwide. Past literature has demonstrated that patients with COPD are at an increased risk of post-operative complications. We assessed the impact of COPD on 30-day outcomes following a 1- to 2-level posterior lumbar fusion (PLF). Read More

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September 2018

Assessment of levels of D-dimer and interferon-γ in pediatric patients with pneumonia and its clinical implication.

Exp Ther Med 2018 Dec 17;16(6):5025-5030. Epub 2018 Oct 17.

The Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, Heilongjiang 161000, P.R. China.

Levels of D-dimer and interferon-γ (INF-γ) in pediatric patients with pneumonia (MPP) were assessed to explore its clinical implication in evaluating the disease severity and patients' prognosis. Enrolled in this study as subjects were 185 pediatric patients with MPP who were admitted to the Department of Pediatrics of the Second Affiliated Hospital of Qiqihar Medical University and the First Hospital of Qiqihar City from January 2017 to October 2017 and 115 healthy children who underwent physical examination during the same time period. Patients were divided into two groups according to the severity of their pneumonia: Severe pneumonia group with 95 patients and mild pneumonia group with 90 patients. Read More

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December 2018

Ventilation/Perfusion SPECT Imaging-Diagnosing Other Cardiopulmonary Diseases Beyond Pulmonary Embolism.

Semin Nucl Med 2019 Jan 20;49(1):4-10. Epub 2018 Nov 20.

Department of Pulmonary Medicine, Heart and Lung Center, Helsinki University Hospital and Helsinki University, Helsinki, Finland. Electronic address:

Ventilation/perfusion single-photon emission computed tomography (V/P SPECT) is the scintigraphic technique recommended primarily for the diagnosis of acute pulmonary embolism (PE) and is golden standard for the diagnosis of chronic PE. Furthermore, interpreting ventilation and corresponding perfusion images enables pattern recognition of many other cardiopulmonary disorders that affect lung function and also allows quantification of their extent. Using Technegas for the ventilation imaging, grading of small airway disease in COPD is possible and the method is recommended for PE diagnosis in patients with severe COPD that is not possible with radiolabelled liquid aerosols. Read More

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January 2019

Serial measurements of KL-6 for monitoring activity and recurrence of interstitial pneumonia with anti-aminoacyl-tRNA synthetase antibody: A retrospective cohort study.

Medicine (Baltimore) 2018 Dec;97(49):e13542

Department of Molecular and Internal Medicine.

The aim of this study was to evaluate whether serial measurements of serum Krebs von den Lungen-6 (KL-6) could be used to monitor disease activity and to detect recurrence in patients with interstitial pneumonia (IP) with anti-aminoacyl-tRNA synthetase antibodies (ARS-IP).This retrospective cohort study included 44 patients with ARS-IP. Thirty-six patients had serial data of blood tests and pulmonary function tests. Read More

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December 2018

Autoimmune interstitial lung disease in Latin-America.

Clin Immunol 2018 Dec 10. Epub 2018 Dec 10.

Department of Research, Hospital Privado de Comunidad, Mar del Plata, Argentina.

Information about the prognosis and natural history of autoimmune interstitial lung diseases (Ai-ILD) is limited. The aim of the study was to evaluate the characteristics of patients diagnosed with Ai-ILD in Latin-America. We conducted an ambispective multicenter cohort study in 25 centers of Argentina, Colombia, and Uruguay between January 2015 and April 2018. Read More

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December 2018

Association between outdoor air pollution levels and inpatient outcomes in pediatric pneumonia hospitalizations, 2007 to 2008.

Acad Pediatr 2018 Dec 10. Epub 2018 Dec 10.

Department of Pediatrics, NYU Langone Health/Bellevue Hospital Center, 462 First Avenue, New York, NY, 10016, USA; Departments of Environmental Medicine and Population Health, NYU School of Medicine, 403 East 34th Street, Rm 115, New York, NY, 10016, USA; NYU Wagner School of Public Service, New York, NY, 403 East 34th Street, Rm 115, New York, NY, 10016, USA; NYU College of Global Public Health, 403 East 34th Street, Rm 115, New York, NY, 10016, USA. Electronic address:

Objective: Pneumonia is a leading cause of pediatric admissions. While air pollutants are associated with poor outcomes, few national studies have examined associations between pollutant levels and inpatient pediatric pneumonia outcomes. We examined the relationship between ozone (O) and fine particulate matter with a diameter ≤2. Read More

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December 2018

Influenza Activity - United States, September 30-December 1, 2018.

MMWR Morb Mortal Wkly Rep 2018 Dec 14;67(49):1369-1371. Epub 2018 Dec 14.

Influenza Division, National Center for Immunization and Respiratory Diseases, CDC.

Influenza activity in the United States was low during October 2018, and, although it increased slowly during November, activity remains low across most of the country.* During the week ending December 1, 2018, the percentage of outpatient visits for influenza-like illness (ILI) was equal to the national baseline (Figure) and was at or slightly above the region-specific baseline in four of the 10 U.S. Read More

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December 2018

Teaching an Old Intensivist Neutrophil Tricks: Using Alveolar Neutrophilia to Diagnose Ventilator-Associated Pneumonia.

Am J Respir Crit Care Med 2018 Dec 13. Epub 2018 Dec 13.

Yale University, Pulmonary and Critical Care Medicine, New Haven, Connecticut, United States ;

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December 2018

Clinical significance and efficacy analysis of atorvastatin in the treatment of patients with cerebral infarction and aspiration pneumonia.

Authors:
Bing Wei Yugeng Liu

Exp Ther Med 2018 Dec 4;16(6):5144-5148. Epub 2018 Oct 4.

Department of Emergency Medicine, Beijing Chaoyang Hospital Jingxi Branch, Capital Medical University, Beijing 100043, P.R. China.

Therapeutic efficacy of the use of oral atorvastatin in the treatment of patients with aspiration pneumonia complicated with cerebral infarction was investigated. Three hundred and fourteen cerebral infarction patients complicated with aspiration pneumonia who were admitted to the emergency department of Beijing Chaoyang Hospital Jingxi Branch from May 2015 to July 2017 were retrospectively analyzed. Among them, 160 patients who took atorvastatin were treated as observation group, and the remaining 154 patients were the control group. Read More

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December 2018

Implementation of Point-of-Care Molecular Diagnostics for Mycoplasma pneumoniae Ensures the Correct Antimicrobial Prescription for Pediatric Pneumonia Patients.

Tohoku J Exp Med 2018 ;246(4):225-231

Department of Pediatrics, Tsukuba Medical Center Hospital.

Mycoplasma pneumoniae is a leading causative pathogen of pneumonia among pediatric patients, and its accurate diagnosis may aid in the selection of appropriate antimicrobial agents. We established a rapid reporting system of a polymerase chain reaction (PCR) examination for M. pneumoniae that enables physicians to obtain test results approximately 90 minutes after ordering the test. Read More

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January 2018

[Analysis of clinical characteristics of bloodstream infection in patients with immune function inhibition].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2018 Nov;30(11):1087-1090

Department of Critical Care Medicine, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, Jiangsu, China. Corresponding author: Gu Qin, Email:

Objective: To analyze the clinical characteristics of bloodstream infection in patients with immune function inhibition.

Methods: A retrospective analysis was conducted. 234 patients with bloodstream infection admitted to intensive care unit (ICU) of the Affiliated Drum Tower Hospital of Nanjing University Medical School from August 1st in 2015 to December 31st in 2017 were enrolled. Read More

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November 2018

[Visualization studies on research status of the ventilator-associated pneumonia based on SinoMed database].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2018 Nov;30(11):1029-1035

Department of Critical Care Medicine, Gansu Provincial People's Hospital, Lanzhou 730000, Gansu, China (Zhao J, Zhang LQ, Zhang DQ, Yuan Y); Gansu University of Traditional Chinese Medicine, Lanzhou 730000, Gansu, China (Zhao J, He TP, Gong D); Evidence-Based Medicine Center of Lanzhou University, Lanzhou 730000, Gansu, China (Tian JH). Corresponding author: Yuan Yuan, Email:

Objective: To survey the distribution pattern and subject domain knowledge of the literatures about ventilator-associated pneumonia (VAP).

Methods: Literatures about VAP published until December 2017 were identified in SinoMed database for statistics and analysis. The information of author, organization and province was extracted by BICOMS software for generating co-occurrence matrix, at the same time, the topic words were cluster analyzed by Gcluto software to generate topical visual surface maps and visualization matrices, and the current research hotspots were analyzed. Read More

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November 2018

[Evaluation value of human antibacterial peptide LL-37 on the prognosis of elderly patients with sepsis].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2018 Nov;30(11):1011-1016

Department of Emergency, East Hospital of Tongji University, Shanghai 200120, China (Guo WN, Wang CM, Huo FJ, Li HQ, Yan YL, Xu SM, Li YS, Bai JW); Institute Pasteur of Shanghai, Chinese Academy of Science, Shanghai 200031, China (Xu HH, Zhang XM). Corresponding author: Bai Jianwen, Email:

Objective: To evaluate the prognostic value of human antibacterial peptide LL-37 in elderly patients with sepsis.

Methods: Elderly sepsis patients over 65-year-old satisfied the diagnostic criteria for sepsis and septic shock admitted to intensive care unit of East Hospital of Tongji University from January 2016 to December 2017 were enrolled (elderly sepsis group). Aged community-acquired pneumonia (CAP) patients hospitalized during the same period were enrolled as a control group for pneumonia, and the aged health check-ups served as a healthy control group during the same period. Read More

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November 2018

Resistance profile of clinically relevant bacterial isolates against fluoroquinolone in Ethiopia: a systematic review and meta-analysis.

BMC Pharmacol Toxicol 2018 Dec 12;19(1):86. Epub 2018 Dec 12.

Department of Medical Laboratory Sciences, College of Health and Medical Sciences, Haramaya University, P.O.Box 235, Harar, Ethiopia.

Background: Fluoroquinolones are among the most frequently utilized antibacterial agents in developing countries like Ethiopia. Ciprofloxacin has become the most prescribed drug within this class and remains as one of the top three antibacterial agents prescribed in Ethiopia. However, several studies indicated that there is a gradual increase of antibacterial resistance. Read More

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December 2018
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Klebsiella pneumoniae liver abscess: a case report.

J Med Case Rep 2018 Dec 13;12(1):367. Epub 2018 Dec 13.

Department of Medicine, Teaching Hospital Kandy, Kandy, Sri Lanka.

Background: Liver abscess has formerly been a polymicrobial infection. Currently, liver abscess due to Klebsiella pneumoniae is increasingly reported, predominantly in Southeast Asia for unknown reasons. Liver abscess due to Klebsiella pneumonia has never been previously reported in Sri Lanka. Read More

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December 2018

What is the impact of the use of transanastomotic feeding tube on patients with esophageal atresia: a systematic review and meta-analysis.

BMC Pediatr 2018 Dec 12;18(1):385. Epub 2018 Dec 12.

Department of Pediatric Surgery, West China Hospital of Sichuan University, #37 Guo-Xue-Xiang, Chengdu, 610041, China.

Background: The transanastomotic feeding tube (TAFT) is widely used around the world in patients with esophageal atresia (EA). However, the safety of the use of TAFT is still unknown and remains to be clarified.

Methods: The following electronic databases were searched: PubMed, EMBASE and Cochrane. Read More

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December 2018