11,712 results match your criteria Pneumonia Aspiration

Predictive power of modified frailty index score for pulmonary complications after major abdominal surgery in the elderly: a single centre prospective cohort study.

Eur Rev Med Pharmacol Sci 2021 May;25(10):3798-3802

Dipartimento di Scienze dell'Emergenza, Anestesiologiche e della Rianimazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Objective: The primary aim of this prospective cohort study was to evaluate the usefulness of the modified Frailty Index (mFI) score to predict postoperative pulmonary complications (PPCs) in elderly patients undergoing major open abdominal surgery. The secondary purpose was to compare the prediction power of mFI, Ariscat (Assess Respiratory Risk in Surgical Patients in Catalonia), and American Society physical status classification (ASA) scores.

Patients And Methods: After local Ethical Committee approval, 105 patients aged ≥65 years undergoing open major abdominal surgery were enrolled. Read More

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Progression of swallowing dysfunction and associated complications of dysphagia in a cohort of patients with serial videofluoroscopic swallow examinations.

R Hanna D R Randall

J Laryngol Otol 2021 Jun 10:1-6. Epub 2021 Jun 10.

Section of Otolaryngology - Head and Neck Surgery, Department of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Canada.

Objective: Dysphagia is a common symptom with associated complications ranging from mild discomfort to life-threatening pulmonary compromise. Videofluoroscopic swallow is the 'gold standard' evaluation for oropharyngeal dysphagia, but little is known about how patients' performance changes over time.

Method: This was a retrospective cohort study evaluating dysphagia patients' clinical course by serial videofluoroscopic swallow study. Read More

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Stroke management in a Swiss community hospital - in close collaboration with a stroke centre.

Swiss Med Wkly 2021 May 7;151:w20490. Epub 2021 Jun 7.

Department of Medicine, Medical Clinic, Spital Uster, Switzerland.

Background: Despite the universal recognition that stroke is a major burden of public health in developed countries, little is known concerning its epidemiology and care outside of stroke centres. The objective of our study was to provide information concerning risk factors for stroke, stroke management and quality of care in a community hospital in Switzerland.

Methods: Retrospective observational in-hospital study of adult stroke patients treated in a community hospital in Switzerland in collaboration with a nearby stroke centre. Read More

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Upper Gastrointestinal Disorders in Adult Patients with Intellectual and Developmental Disabilities.

Cureus 2021 Jun 2;13(6):e15384. Epub 2021 Jun 2.

Internal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

The purpose of this literature review is to address the diagnosis and treatment of upper gastrointestinal (GI) disorders in patients with intellectual and developmental disabilities (IDD). Manifestations of upper GI dysmotility and disorders include dysphagia, pulmonary aspiration, malnutrition, gastroesophageal reflux, and gastritis, all of which can impact a person's quality of life and lead to chronic, life-threatening conditions. This article will explore the existing diagnostic methods and treatments for gastrointestinal disorders as they relate to patients with IDD. Read More

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Use of nebulised N-acetylcysteine as a life-saving mucolytic in intensive care: A case report.

J Intensive Care Soc 2020 Nov 19;21(4):296-298. Epub 2019 Sep 19.

Sandwell and West Birmingham Hospitals NHS Trust, West Bromwich, UK.

We present a case of critical airway obstruction secondary to a solid tracheal mucus plug in a patient with pneumonia. Following failed conventional mucolysis therapy, nebulised N-acetylcysteine acted as a life-saving mucolytic, and prevented imminent cardiorespiratory arrest. Use of oral N-acetylcysteine as a mucolytic has been long established within respiratory medicine in managing chronic airway disease, but is rarely utilised in critically ill or mechanically ventilated patients due to the lack of comparative studies in literature. Read More

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November 2020

Timing of nasogastric tube insertion and the risk of postoperative pneumonia: an international, prospective cohort study.


Colorectal Dis 2020 Dec 18;22(12):2288-2297. Epub 2020 Sep 18.

Aim: Aspiration is a common cause of pneumonia in patients with postoperative ileus. Insertion of a nasogastric tube (NGT) is often performed, but this can be distressing. The aim of this study was to determine whether the timing of NGT insertion after surgery (before versus after vomiting) was associated with reduced rates of pneumonia in patients undergoing elective colorectal surgery. Read More

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December 2020

Prevention of VAP: Endless evolving evidences-systematic literature review.

Nurs Forum 2021 Jun 6. Epub 2021 Jun 6.

Adult Health & Critical Care, College of Nursing, Sultan Qaboos University, Al Khod, Muscat, Sultanate of Oman.

Introduction: Prevention of ventilator associated pneumonia (VAP) is the focus in critical care units. Immunocompromised patients, older adults, and postoperative patients are at greater risk for VAP. With the dynamic changes in the empirical world, updated evidence must be used to guide the standard of practice. Read More

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Aspiration pneumonia: A renewed perspective and practical approach.

Respir Med 2021 May 26;185:106485. Epub 2021 May 26.

Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain; Universitat de Barcelona, Barcelona, Spain; Service of Pneumology, Institut Clínic Del Torax, Institut D'Investigació Biomédica Agustí Pi I Sunyer (IDIBAPS), Hospital Clínic de Barcelona, Barcelona, Spain. Electronic address:

Aspiration pneumonia (AP) is a sub-type of community-acquired pneumonia (CAP) still poorly recognized especially in the absence of an aspiration event. A further difficulty is the differentiation between AP and aspiration pneumonitis. From a clinical perspective, AP is becoming increasingly relevant as a potential cause of severe and life-threatening respiratory infection among frail and very old patients, particularly among those with CAP requiring inpatient care. Read More

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Relationship between tongue pressure and dysphagia diet in patients with acute stroke.

PLoS One 2021 4;16(6):e0252837. Epub 2021 Jun 4.

Department of Neurosurgery, Suiseikai Kajikawa Hospital, Hiroshima, Japan.

A dysphagia diet is important for patients with stroke to help manage their nutritional state and prevent aspiration pneumonia. Tongue pressure measurement is a simple, non-invasive, and objective method for diagnosing dysphagia. We hypothesized that tongue pressure may be useful in making a choice of diet for patients with acute stroke. Read More

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Predictors of the need for prophylactic percutaneous endoscopic gastrostomy in head and neck cancer patients treated with concurrent chemoradiotherapy.

Int J Clin Oncol 2021 Jun 4. Epub 2021 Jun 4.

Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita-ku, Sapporo, 060-8638, Japan.

Background: We investigated whether prophylactic percutaneous endoscopic gastrostomy (PEG) is used effectively for patients treated with definitive concurrent chemoradiotherapy (CCRT) and the predictors of the need for PEG.

Methods: 326 patients with laryngeal, oropharyngeal or hypopharyngeal cancers were retrospectively reviewed.

Results: The PEG tube use group had more favorable results than the total parenteral nutrition and nasogastric tube groups in terms of rate of serum albumin loss, incidence of severe fever and aspiration pneumonia, CCRT completion rate and hospitalization period. Read More

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Outcomes of elderly patients with organophosphate intoxication.

Sci Rep 2021 Jun 2;11(1):11615. Epub 2021 Jun 2.

Department of Nephrology, Clinical Poison Center, Kidney Research Center, Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, and Chang Gung University, 199 Tung Hwa North Road, Taipei, Taoyuan, 105, Taiwan.

This study analysed the clinical patterns and outcomes of elderly patients with organophosphate intoxication. A total of 71 elderly patients with organophosphate poisoning were seen between 2008 and 2017. Patients were stratified into two subgroups: survivors (n = 57) or nonsurvivors (n = 14). Read More

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Determining growth inhibition of Candida albicans biofilm on denture materials after application of an organoselenium-containing dental sealant.

J Prosthet Dent 2021 May 30. Epub 2021 May 30.

Professor and Director of Cariology, Department of Comprehensive Dentistry, UT Health School of Dentistry, San Antonio, Texas. Electronic address:

Statement Of Problem: Denture stomatitis is a chronic inflammatory condition caused by the formation of Candida albicans biofilm on denture bases. It is associated with aggravating intraoral pain, itching, and burning sensations. It can also potentiate cardiovascular diseases and aspiration pneumonia. Read More

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Clinical predictors and neural correlates for compromised swallowing safety in Huntington's Disease.

Eur J Neurol 2021 Jun 2. Epub 2021 Jun 2.

Department of Neurology, Medical Faculty, RWTH Aachen University, Aachen, Germany.

Background: Dysphagia is one of the most common and important complications in Huntington's Disease (HD), frequently leading to aspiration pneumonia and mortality. Objective estimates of prevalence using instrumental diagnostics and data on neural correlates of dysphagia in HD are scarce or lacking entirely. Similarly, its correlation with other clinical markers is still not fully known. Read More

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Measuring attentiveness toward oral care needs: a comparative study of Indonesian care workers in Japan and Indonesia.

Hum Resour Health 2021 Jun 1;19(1):71. Epub 2021 Jun 1.

Faculty of Health Sciences, University of Respati Indonesia, Jakarta, Indonesia.

Background: Japan has opened its labor market to care workers from Indonesia under the Japan-Indonesia Economic Partnership Agreement (EPA). However, few studies have examined the types of care skills transferred between countries. We therefore analyzed Indonesian care workers employed in Japan and Indonesia to identify discrepancies in their attentiveness toward oral care in older adults. Read More

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Diagnostic Procedures, Diagnoses, and Treatment Outcomes of Patients with Presumptive Tuberculosis Pleural Effusion in Uzbekistan.

Int J Environ Res Public Health 2021 May 27;18(11). Epub 2021 May 27.

World Health Organization Regional Office for Europe, UN City, Marmorvej 51, DK-2100 Copenhagen, Denmark.

Tuberculosis (TB) pleural effusion (TPE) is the second most common manifestation of extrapulmonary TB (EPTB), which remains a great diagnostic challenge worldwide. In Uzbekistan, there has been no formal evaluation of the actual practices of diagnosing and treating TPE. Our cohort study therefore aimed to describe the frequency and types of different diagnostic procedures of TPE during 2017-2018 and assess the association of baseline characteristics and establish diagnostic methods with TB treatment outcomes. Read More

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Usefulness of the Modified Videofluoroscopic Dysphagia Scale in Choosing the Feeding Method for Stroke Patients with Dysphagia.

Healthcare (Basel) 2021 May 27;9(6). Epub 2021 May 27.

Department of Physical Medicine and Rehabilitation, College of Medicine, Ulsan University Hospital, University of Ulsan, Ulsan 44610, Korea.

Introduction: The Videofluoroscopic Dysphagia Scale (VDS) is used to predict the long-term prognosis of dysphagia in patients with strokes. However, the inter-rater reliability of the VDS was low in a previous study. To overcome the mentioned limitations of the VDS, the modified version of the VDS (mVDS) was created and clinically applied to evaluate its usefulness in choosing the feeding method for stroke patients with dysphagia. Read More

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Respiratory Dysfunctions in Parkinson's Disease Patients.

Brain Sci 2021 May 4;11(5). Epub 2021 May 4.

Department of Neurology, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.

Respiratory dysfunctions have been associated with Parkinson's disease since the first observations of the disease in 1817. Patients with Parkinson's disease frequently present respiratory disorders with obstructive ventilatory patterns and restrictive modifications, as well as limitations in respiratory volumes. In addition, respiratory impairments are observed due to the rigidity and kyphosis that Parkinson's disease patients experience. Read More

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Potential adverse events in Japanese women who received tozinameran (BNT162b2, Pfizer-BioNTech).

J Pharm Policy Pract 2021 May 31;14(1):46. Epub 2021 May 31.

Department of Medical Informatics, Kagawa University Hospital, Miki-cho, Kagawa, 761-0793, Japan.

Reports of cerebral venous sinus thrombosis and intracranial hemorrhage (ICH) following the administration of coronavirus vaccines have raised concerns regarding their safety. Although no regulatory authority has recognized ICH as an adverse event associated with tozinameran (BNT162b2, Pfizer-BioNTech), fatal and non-fatal cases have been reported. In Japan, 10 fatal cases (five men and women) have been reported to date. Read More

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Reduction in Short- and Long-term Pneumonia Rate With Laryngoplasty for Unilateral Vocal Fold Paralysis.

Otolaryngol Head Neck Surg 2021 Jun 1:1945998211015174. Epub 2021 Jun 1.

Department of Otolaryngology-Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi.

Objective: To examine the association of laryngoplasty, voice therapy, and pneumonia rate in patients with unilateral vocal fold paralysis (UVFP).

Study Design: Population-based retrospective cohort study.

Setting: Data were collected from the LHID2000 (Longitudinal Health Insurance Database 2000), containing the information of 1 million randomly selected patients in Taiwan. Read More

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A post-marketing observational study of ramucirumab in patients with gastric cancer in Japan.

Gastric Cancer 2021 May 28. Epub 2021 May 28.

, Eli Lilly Japan K.K., Lilly Plaza One Building, 5-1-28 Isogamidori, Chuo-Ku, Kobe, Hyogo, 651-0086, Japan.

Background: This study evaluated the safety and effectiveness of ramucirumab monotherapy and combination therapy for advanced gastric cancer in the real-world setting.

Methods: This single-arm, prospective, multicenter, non-interventional, observational, post-marketing study was conducted in Japan from August 2015 to March 2019. Patients with unresectable advanced or recurrent gastric cancer and newly prescribed ramucirumab were followed for up to 12 months after first treatment. Read More

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The role of oral microbiome in respiratory health and diseases.

Respir Med 2021 May 20;185:106475. Epub 2021 May 20.

Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Institute of Oral Disease, Guangzhou Medical University, Guangzhou, China. Electronic address:

The oral cavity (mouth) has various microbial habitats, including, teeth, gingival sulcus, gingiva, tongue, inner cheek, hard palate, and soft palate. The human oral cavity houses the second most diverse microbiome in the body harboring over 700 bacterial species. The fine-tuned equilibrium of the oral microbiome ecosystem maintains oral health. Read More

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Clinicopathologic Features of Oculopharyngodistal Myopathy With LRP12 CGG Repeat Expansions Compared With Other Oculopharyngodistal Myopathy Subtypes.

JAMA Neurol 2021 May 28. Epub 2021 May 28.

Department of Neurology, Nara Medical University, Nara, Japan.

Importance: Repeat expansion of CGG in LRP12 has been identified as the causative variation of oculopharyngodistal myopathy (OPDM). However, to our knowledge, the clinicopathologic features of OPDM with CGG repeat expansion in LRP12 (hereafter referred to as OPDM_LRP12) remain unknown.

Objective: To identify and characterize the clinicopathologic features of patients with OPDM_LRP12. Read More

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Percutaneous Endoscopic Gastrostomy Tube Insertion in Patient With Situs Inversus Totalis.

Cureus 2021 Apr 23;13(4):e14650. Epub 2021 Apr 23.

Gastroenterology, Hamad Medical Corporation, Doha, QAT.

Situs inversus totalis (SIT) is a rare congenital condition in which the abdominal and thoracic organs are completely reversed from right to left, and their diagnosis is usually incidental. However, patients with SIT need a comprehensive radiological evaluation before undertaking any invasive procedures. Percutaneous endoscopic gastrostomy (PEG) insertion is an effective procedure for enteral feeding in patients with difficulty swallowing. Read More

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Oral Care in Hospital Settings: Breaking the Vicious Circle of Older Adult Deconditioning.

J Gerontol Nurs 2021 Jun 1;47(6):7-12. Epub 2021 Jun 1.

Hospitalized older adults frequently develop aspiration pneumonia, swallowing dys-function (dysphagia), and sarcopenia. In the current study, we propose a framework that incorporates these three factors into a vicious circle that leads to deconditioning, a condition frequently experienced by this vulnerable population. Viewing aspiration pneumonia, dysphagia, and sarcopenia, along with their interrelationships through the lens of this vicious circle, illuminates the critical role that oral health plays in deconditioning. Read More

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Promoting subglottic secretion drainage: a quality improvement project in a UK critical care unit.

BMJ Open Qual 2021 May;10(2)

Department of Critical Care, Royal Cornwall Hospitals NHS Trust, Truro, UK.

The aim of the study was to promote the practice of subglottic secretion drainage (SSD) in a UK critical care unit. SSD is a technique employed to reduce microaspiration of oropharyngeal secretions in patients with cuffed endotracheal airways. Aspiration of oropharyngeal secretions is the accepted cause of the majority of ventilator-associated pneumonia (VAP), a complication of invasive ventilation with high associated mortality. Read More

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The incidence and clinical outcomes of postextubation dysphagia in a regional critical care setting.

Aust Crit Care 2021 May 22. Epub 2021 May 22.

Department of Intensive Care Medicine, Bendigo Health, Bendigo, Victoria, Australia; Department of Intensive Care Medicine, Goulburn Valley Health, Shepparton, Victoria, Australia; Department of Medicine University of Queensland, Australia; Department of Medicine University of Melbourne, Australia.

Background: Postextubation dysphagia (PED) has been shown to occur in 41% of critically ill patients requiring endotracheal intubation. With one-third of patients with PED experiencing silent aspiration, it is reasonable to anticipate negative health outcomes are likely, although this has not yet been systematically explored in an Australian context.

Objectives: The aim of the study was to determine the impact of PED, in a regional Australian intensive care unit (ICU), on rates of pneumonia, the length of stay in the ICU and hospital, and healthcare expenditure. Read More

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Poppy Intoxication in Infants and Children: Hazards of a Folk Remedy.

J Coll Physicians Surg Pak 2021 May;30(5):576-581

Department of Paediatrics, Mardan Medical Complex, Mardan, Pakistan.

Objective: To study the clinical and laboratory profile in infants and children presented in the tertiary care hospital with poppy intake and to compare the profile between those who survived with those who died.

Study Design:   Observational study. Study Place and Duration: Department Of Paediatrics, Mardan Medical Complex, Mardan, KPK, Pakistan from January 2019 to January 2020. Read More

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Neglected Foreign Body Aspiration Mimicking Lung Cancer: A Case Report.

Cureus 2021 Apr 19;13(4):e14566. Epub 2021 Apr 19.

Laparoscopic Surgery, National Guard Hospital, Al Madinah, SAU.

Tracheobronchial aspiration is relatively rare in adults as compared to children although incidence rates tend to increase with advancing age. The diagnosis of tracheobronchial foreign body aspiration can be challenging and warrants a high index of suspicion as the symptoms are often vague and patients may fail to recall the history of choking. The failure to diagnose the condition promptly may result in serious complications such as recurrent pneumonia, hemoptysis, or atelectasis. Read More

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[Granulomatous lung disease induced by kayexalate inhalation during immunotherapy for metastatic melanoma].

Rev Mal Respir 2021 Jun 20;38(6):664-668. Epub 2021 May 20.

Département de dermatologie, CHRU de Montpellier et université de Montpellier, Montpellier, France.

Introduction: When a patient treated by immune checkpoint inhibitors for metastatic melanoma presents with pulmonary symptoms, several diagnoses are possible. We report a case of acute granulomatous lung disease secondary to repeated kayexalate inhalations, and probably stimulated by immunotherapy.

Case Report: A patient treated with pembrolizumab and then ipilimumab presented with fever and acute shortness of breath. Read More

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Translation of the Chinese version of the Self-Care for Aspiration Pneumonia Prevention Scale and its validation among Chinese community dwelling elderly with risk of dysphasia.

Nurs Open 2021 May 21. Epub 2021 May 21.

Department of Nursing, Jinzhou Medical University, Jinzhou, China.

Aim: To translate the Self-Care for Aspiration Pneumonia Prevention Scale into the Chinese and validate its reliability and validity among community dwelling elderly with risk of dysphasia.

Design: A cross-sectional survey.

Methods: A total of 430 elderly with risk of dysphasia were recruited. Read More

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