663 results match your criteria Pneumocystis Carinii Imaging


Pneumocystis jirovecii infection of bilateral adrenal glands in an immunocompetent adult: a case report.

J R Coll Physicians Edinb 2019 09;49(3):222-224

117 B L Taneja Building, Maulana Azad Medical College, Bahadur Shah Zafar Marg, New Delhi 110002, India,

Pneumocystis jirovecii (PJ) infection is one of the most common opportunistic infections occurring in patients with HIV/AIDS and other immunocompromised states. It is not known to cause clinically significant illness in immunocompetent hosts. We report a 48-year-old HIV-negative, diabetic male who presented with fever and adrenal insufficiency. Read More

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http://dx.doi.org/10.4997/JRCPE.2019.310DOI Listing
September 2019
4 Reads

Pneumocystis jirovecii pneumonia prophylaxis in hematopoietic stem cell transplantation, is it acceptable to wait for the engraftment for restarting it?

Transpl Infect Dis 2019 10 21;21(5):e13155. Epub 2019 Aug 21.

IRCCS Istituto Giannina Gaslini, Children's Hospital Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/tid.13155DOI Listing
October 2019
1 Read

Serum Soluble Interleukin-2 Receptor Is a Biomarker for Pneumocystis jirovecii Pneumonia among Patients with Rheumatoid Arthritis under Methotrexate Therapy.

Tohoku J Exp Med 2019 07;248(3):209-216

Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences.

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic joint inflammation and may manifest as interstitial pneumonia (IP). Methotrexate (MTX) is one of the main therapeutic drugs used for RA, but MTX could cause severe side effects, including Pneumocystis jirovecii pneumonia (PCP) and IP. Owing to similar symptoms, it is sometimes difficult to discriminate MTX therapy-associated PCP (MTX-PCP) and MTX therapy-associated IP (MTX-IP). Read More

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https://www.jstage.jst.go.jp/article/tjem/248/3/248_209/_art
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http://dx.doi.org/10.1620/tjem.248.209DOI Listing
July 2019
3 Reads

Pneumocystis jirovecii pneumonia at chest High-resolution Computed Tomography (HRCT) in non-HIV immunocompromised patients: Spectrum of findings and mimickers.

Eur J Radiol 2019 Jul 1;116:116-127. Epub 2019 May 1.

Institute of Radiology, Department of Medicine, University of Udine, Azienda Sanitaria Universitaria Integrata di Udine, p.le S. Maria della Misericordia 15, 33100, Udine, Italy. Electronic address:

Pneumocystis jirovecii pneumonia (PJP) has emerged as a main issue in non Human Immunodeficiency Virus (HIV) immunocompromised hosts, exposing patients to high mortality rates, especially when the diagnosis is delayed. Since microbiological confirmation is often unfeasible or difficult to obtain, High-resolution Computed Tomography (HRCT) represents a main tool for guiding the diagnosis in the appropriate clinical scenario. Nevertheless, radiologists must be aware that PJP at HRCT is a multifaceted process, with a variety of common and less frequent findings, along with a broad spectrum of infectious (e. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.04.025DOI Listing
July 2019
22 Reads

Potential role of CT-textural features for differentiation between viral interstitial pneumonias, pneumocystis jirovecii pneumonia and diffuse alveolar hemorrhage in early stages of disease: a proof of principle.

BMC Med Imaging 2019 05 21;19(1):39. Epub 2019 May 21.

Department of Diagnostic and Interventional Radiology, Eberhard-Karls-University, Hoppe-Seyler-Str.3, 72076, Tübingen, Germany.

Background: Pulmonary involvement is common in several infectious and non-infectious diagnostic settings. Imaging findings consistently overlap and are therefore difficult to differentiate by chest-CT. The aim of this study was to evaluate the role of CT-textural features(CTTA) for discrimination between atypical viral (respiratory-syncitial-virus(RSV) and herpes-simplex-1-virus (HSV1)), fungal (pneumocystis-jirovecii-pneumonia(PJP)) interstitial pneumonias and alveolar hemorrhage. Read More

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http://dx.doi.org/10.1186/s12880-019-0338-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530105PMC
May 2019
8 Reads

PJP infection in a patient with high output ileostomy and selective IgA deficiency.

QJM 2019 Jun;112(6):445-446

Respiratory Department, Portiuncula University Hospital, Ballinasloe, Co., Galway H53 T971, Ireland.

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http://dx.doi.org/10.1093/qjmed/hcz067DOI Listing
June 2019
8 Reads

Case report: new development of fibrosing interstitial lung disease triggered by HIV-related pneumocystis pneumonia.

BMC Pulm Med 2019 Mar 18;19(1):65. Epub 2019 Mar 18.

AIDS Clinical Center, National Center of Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.

Background: Fibrosing interstitial lung disease is the poor prognostic non-infectious lung disease by unknown etiology. Here, we present one case developing interstitial pneumonia with fibrosis after treatment of pneumocystis pneumonia (PCP) in newly diagnosed HIV-1 infected case.

Case Presentation: A previously healthy 63-year old male was referred to our institute because of protracted dyspnea on effort in 2 weeks after pneumocystis pneumonia treatment. Read More

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http://dx.doi.org/10.1186/s12890-019-0831-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423812PMC
March 2019
17 Reads

Pneumocystis Pneumonia Complicated by Extensive Diffuse Pneumatoceles.

Am J Med 2019 05 16;132(5):e562-e563. Epub 2019 Jan 16.

Division of Infectious Diseases, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.amjmed.2018.12.029DOI Listing
May 2019
3 Reads

Pneumocystis jirovecii-related spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema in a liver transplant recipient: a case report.

BMC Infect Dis 2019 Jan 18;19(1):66. Epub 2019 Jan 18.

Department of Surgery, The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong, China.

Background: Pneumocystis pneumonia (PCP) is a common opportunistic infection caused by Pneumocystis jirovecii. Its incidence at 2 years or more after liver transplant (LT) is < 0.1%. Read More

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http://dx.doi.org/10.1186/s12879-019-3723-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339407PMC
January 2019
13 Reads

Challenging Alveolar Hemorrhage Complicating Pneumonia After Liver Transplantation: A Case Report.

Transplant Proc 2018 Dec 22;50(10):4046-4049. Epub 2018 Jun 22.

Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.

Alveolar hemorrhage is a life-threatening clinical syndrome often initially thought to be atypical pneumonia. Association with hematopoietic stem cell transplantation is well studied, but not with solid organ transplantation. We report a case of a 54-year-old woman presented with fever and shortness of breath on the third posttransplant day after deceased donor liver transplantation. Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.06.017DOI Listing
December 2018
3 Reads

Round opacity as a presentation of pneumocystis jirovecii pneumonia in an HIV-infected patient.

Am J Emerg Med 2019 01 30;37(1):176.e3-176.e4. Epub 2018 Sep 30.

Department of Internal Medicine, "Dr. José E. González" University Hospital of the School of Medicine of the Nuevo León Autonomous University, Monterrey, Mexico.

We present the case of a human immunodeficiency virus (HIV)-infected patient who arrived at our emergency department with fever, headache and exertional dyspnea. Throughout their stay, a chest x-ray was taken and a rounded opacity in his left lung was observed. CT images showed same abnormality and also ground glass opacities were seen. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07356757183080
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http://dx.doi.org/10.1016/j.ajem.2018.09.051DOI Listing
January 2019
5 Reads

Lung ultrasound in the management of pneumocystis pneumonia: A case series.

Int J STD AIDS 2019 02 20;30(2):188-193. Epub 2018 Sep 20.

Division of Infectious Diseases, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, Università degli Studi di Milano, Milan, Italy.

Despite the decline in HIV mortality and morbidity, Pneumocystis jirovecii pneumonia (PJP) is still frequently seen, particularly in patients with a low CD4+ cell count. We present a case series where we analyzed the possible role of lung ultrasound (LUS) in the management of PJP in a real-life clinical setting. We describe the ultrasound findings from a consecutive series of six HIV patients hospitalized for PJP, all with a favorable outcome, and evaluated with LUS at admission in our ward and then repeated this once during the hospitalization. Read More

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http://journals.sagepub.com/doi/10.1177/0956462418797872
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http://dx.doi.org/10.1177/0956462418797872DOI Listing
February 2019
33 Reads

A cluster of cases of pneumocystis pneumonia identified by shotgun metagenomics approach.

J Infect 2019 02 24;78(2):158-169. Epub 2018 Aug 24.

Clinical Laboratory of BGI Health, BGI-genomics, BGI-Shenzhen, Shenzhen 518083, China.

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https://linkinghub.elsevier.com/retrieve/pii/S01634453183025
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http://dx.doi.org/10.1016/j.jinf.2018.08.013DOI Listing
February 2019
42 Reads
4.440 Impact Factor

Nodular granulomatous Pneumocystis jiroveci pneumonia consequent to delayed immune reconstitution inflammatory syndrome.

Int J STD AIDS 2018 12 16;29(14):1451-1453. Epub 2018 Aug 16.

1 Division of Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, Norfolk, VA, USA.

Although Pneumocystis jiroveci pneumonia (PCP) is a frequent manifestation of acquired immune deficiency syndrome (AIDS), the granulomatous form is uncommon. Here, we present an unusual case of granulomatous PCP consequent to immune reconstitution inflammatory syndrome (IRIS) after highly active antiretroviral therapy. A 36-year-old woman with human immunodeficiency virus (HIV) presented with cough and dyspnea that were attributed to typical PCP associated with AIDS. Read More

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http://dx.doi.org/10.1177/0956462418787603DOI Listing
December 2018
5 Reads

A Multivariable Prediction Model for Pneumocystis jirovecii Pneumonia in Hematology Patients with Acute Respiratory Failure.

Am J Respir Crit Care Med 2018 12;198(12):1519-1526

1 Medical ICU and.

Rationale: The incidence of Pneumocystis jirovecii pneumonia (PjP) is rising. Longer time to treatment is associated with higher mortality.

Objectives: To develop a multivariable risk prediction model for PjP diagnosis. Read More

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http://dx.doi.org/10.1164/rccm.201712-2452OCDOI Listing
December 2018
39 Reads

pneumonia in a patient taking Benepali for rheumatoid arthritis.

BMJ Case Rep 2018 Apr 21;2018. Epub 2018 Apr 21.

Rheumatology, Glasgow Royal Infirmary, Glasgow, UK.

We present a case of a 57-year-old woman who contracted pneumonia while on Benepali, the biosimilar version of etanercept for rheumatoid arthritis. She had seropositive erosive disease. She was admitted to clinic with a 2-week history of dyspnoea, dry cough and fever. Read More

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http://dx.doi.org/10.1136/bcr-2018-224764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926557PMC
April 2018
12 Reads

Clinical, Diagnostic, and Treatment Disparities between HIV-Infected and Non-HIV-Infected Immunocompromised Patients with Pneumocystis jirovecii Pneumonia.

Respiration 2018;96(1):52-65. Epub 2018 Apr 10.

Division of Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.

The substantial decline in the Pneumocystis jirovecii pneumonia (PCP) incidence in HIV-infected patients after the introduction of antiretroviral therapy (ART) in resource-rich settings and the growing number of non-HIV-infected immunocompromised patients at risk leads to considerable epidemiologic changes with clinical, diagnostic, and treatment consequences for physicians. HIV-infected patients usually develop a subacute course of disease, while non-HIV-infected immunocompromised patients are characterized by a rapid disease progression with higher risk of respiratory failure and higher mortality. The main symptoms usually include exertional dyspnea, dry cough, and subfebrile temperature or fever. Read More

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http://dx.doi.org/10.1159/000487713DOI Listing
December 2018
34 Reads
2.593 Impact Factor

Atypical Presentation of Pneumocystis jirovecii Infection in HIV Infected Patients: Three Different Manifestations.

J Korean Med Sci 2018 Apr 9;33(15):e115. Epub 2018 Apr 9.

Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.

Advances in the treatment and prevention of Pneumocystis jirovecii infection (PJI) in human immunodeficiency virus (HIV) patients decreased incidence and mortality dramatically, however, it may be associated with an increased frequency of unusual manifestation such as cystic formation, pneumothorax, focal infiltration, nodular formation, or extrapulmonary lesions. We report three cases of PJI with atypical manifestations. Each case demonstrates different clinical features: multiple nodular pulmonary lesion (32-year-old man with abnormal chest X-ray finding), subpleural mass-like lesion (43-year-old man with left visual loss and right pleuritic chest pain), and extrapulmonary mass-like lesions in the liver, lymph nodes, and small bowel (39-year-old man with cough, sputum, and dyspnea). Read More

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https://jkms.org/DOIx.php?id=10.3346/jkms.2018.33.e115
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http://dx.doi.org/10.3346/jkms.2018.33.e115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890084PMC
April 2018
30 Reads

CT findings in Pneumocystis carinii pneumonia in five dogs.

J Small Anim Pract 2018 Mar 25. Epub 2018 Mar 25.

Small Animal Teaching Hospital, University of Liverpool, Neston, Cheshire, CH64 7TE, UK.

Pneumocystis carinii pneumonia is a rare disease in dogs. It is primarily reported in cavalier King Charles spaniels and miniature dachshunds with suspected underlying immunodeficiency. This case series reports the findings in five dogs (four cavalier King Charles spaniels and one Bedlington terrier) with confirmed P. Read More

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http://doi.wiley.com/10.1111/jsap.12833
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http://dx.doi.org/10.1111/jsap.12833DOI Listing
March 2018
5 Reads

Nonopportunistic infection leading to rapidly progressive dementia in a patient with HIV/AIDS: A case report.

Medicine (Baltimore) 2018 Mar;97(12):e0162

Karolinska University Hospital Huddinge, Department of Infectious Diseases.

Rationale: Cognitive dysfunction is a common presenting symptom in patients with HIV/AIDS. It is usually directly associated with HIV infection or due to opportunistic infection. Rapidly progressive dementia, however, is rarely observed in acute HIV infection or during immune reconstitution. Read More

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http://Insights.ovid.com/crossref?an=00005792-201803230-0001
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http://dx.doi.org/10.1097/MD.0000000000010162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895346PMC
March 2018
30 Reads
5.720 Impact Factor

Pneumocystis jirovecii pneumonia induced by low-dose methotrexate in a patient with chronic urticaria.

An Bras Dermatol 2017 May-Jun;92(3):401-403

Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center - Taipei, Taiwan, Republic of China.

Methotrexate has immunosuppressive effects and is administered for refractory chronic urticaria. We present a case of Pneumocystis jirovecii pneumonia in a patient with refractory chronic urticaria managed by low-dose weekly methotrexate treatment (total cumulative dose 195mg). Our study highlights the importance of providing prompt diagnosis and treatment of Pneumocystis jirovecii pneumonia in patients with chronic urticaria under methotrexate therapy. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20175392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514587PMC
January 2018
13 Reads

Ectopic ACTH syndrome complicated by multiple opportunistic infections treated with percutaneous ablation of the adrenal glands.

BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.

Department of Medicine, University of British Columbia, Vancouver, Canada.

Ectopic adrenocorticotropic hormone (ACTH)-related Cushing's syndrome can lead to multiple complications including severe immunosuppression. If the ACTH-secreting tumour cannot be found, definitive treatment is surgical adrenalectomy, typically followed by glucocorticoid replacement. Here, we present a case of fulminant respiratory failure secondary to coinfection with and cytomegalovirus in a patient with ectopic ACTH-dependent Cushing's syndrome with occult primary. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2017-22158
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http://dx.doi.org/10.1136/bcr-2017-221580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695357PMC
November 2017
10 Reads

Extreme Tetralogy of Fallot With Polycythemia in a Ferret (Mustela putorius furo).

Top Companion Anim Med 2017 Jun 10;32(2):80-85. Epub 2017 Aug 10.

Department of Medicina I Cirurgia Animals, Universitat Autònoma de Barcelona, Barcelona, Spain.

A 5-month-old, intact male ferret (Mustela putorius furo) was presented with apathy, tachypnea and exercise intolerance. On initial physical examination, tachypnea and cyanosis were the two primary clinical signs detected. The complete blood count also revealed a severe polycythemia, with lymphopenia, neutrophilia and eosinophilia. Read More

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http://dx.doi.org/10.1053/j.tcam.2017.08.001DOI Listing
June 2017
66 Reads

HIV-related pneumonia managed with caspofungin and veno-venous extracorporeal membrane oxygenation rescue therapy.

BMJ Case Rep 2017 Oct 4;2017. Epub 2017 Oct 4.

Adult Intensive Care Unit, Royal Brompton and Harefield NHS Foundation Trust, Anaesthesia and Critical Care, London, UK.

Patients with pneumocystis pneumonia have a risk of progressing to acute respiratory failure necessitating admission to intensive care. The case described is of a patient with a newly diagnosed HIV infection presenting with pneumocystis pneumonia. Despite initiating the appropriate pharmacological treatment the patient's clinical condition deteriorated, and required both rescue pharmacological therapy with echinocandins as well as respiratory support with extracorporeal membrane oxygenation therapy. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2017-22121
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http://dx.doi.org/10.1136/bcr-2017-221214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652506PMC
October 2017
60 Reads

Clinical Manifestations and Prognostic Factors of Pneumocystis jirovecii Pneumonia without HIV.

Chemotherapy 2017 19;62(6):343-349. Epub 2017 Jul 19.

Division of Respiratory Medicine and Allergology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Japan.

Introduction: Pneumocystis jirovecii pneumonia (PCP) can occur in HIV patients but also in those without HIV (non-HIV PCP) but with other causes of immunodeficiency including malignancy or rheumatic diseases.

Objective And Methods: To evaluate the clinical presentation and prognostic factors of non-HIV PCP, we retrospectively reviewed all patients diagnosed as having PCP without HIV at Kameda Medical Center, Chiba, Japan, from January 2005 until June 2012. For the purpose of examining a prognostic factor for non-HIV PCP with 30-day mortality, we compared the characteristics of patients, clinical symptoms, radiological images, Eastern Cooperative Oncology Group performance status (PS), and the time from the onset of respiratory symptoms to the start of therapy, in both survival and fatality groups. Read More

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http://dx.doi.org/10.1159/000477332DOI Listing
March 2018
64 Reads

Colonization Density of the Upper Respiratory Tract as a Predictor of Pneumonia-Haemophilus influenzae, Moraxella catarrhalis, Staphylococcus aureus, and Pneumocystis jirovecii.

Clin Infect Dis 2017 Jun;64(suppl_3):S328-S336

Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Background.: There is limited information on the association between colonization density of upper respiratory tract colonizers and pathogen-specific pneumonia. We assessed this association for Haemophilus influenzae, Moraxella catarrhalis, Staphylococcus aureus, and Pneumocystis jirovecii. Read More

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http://dx.doi.org/10.1093/cid/cix104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612712PMC
June 2017
110 Reads

Pneumocystis carinii infection with severe pneumomediastinum and lymph node involvement in a Whippet mixed-breed dog.

J Vet Diagn Invest 2017 Sep 26;29(5):757-762. Epub 2017 May 26.

Institute of Pathology and Forensic Veterinary Medicine (Weissenbacher-Lang, Fuchs-Baumgartinger, Klang, Weissenböck), University of Veterinary Medicine Vienna, Vienna, Austria.

A 3.5-y-old Whippet mixed-breed dog was presented with a history of respiratory distress, exercise intolerance, and generalized demodicosis. Hematologic alterations included marked leukocytosis and neutrophilia. Read More

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http://journals.sagepub.com/doi/10.1177/1040638717710237
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http://dx.doi.org/10.1177/1040638717710237DOI Listing
September 2017
85 Reads

Infectious disease ward admission positively influences P. jiroveci pneumonia (PjP) outcome: A retrospective analysis of 116 HIV-positive and HIV-negative immunocompromised patients.

PLoS One 2017 15;12(5):e0176881. Epub 2017 May 15.

Infectious Diseases, Tor Vergata University, Rome, Italy.

P. jiroveci (Pj) causes a potentially fatal pneumonia in immunocompromised patients and the factors associated with a bad outcome are poorly understood. A retrospective analysis on Pj pneumonia (PjP) cases occurring in Tor Vergata University Hospital, Italy, during the period 2011-2015. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176881PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432209PMC
September 2017
87 Reads

Nodular Regenerative Hyperplasia: A Case of Rare Prognosis.

J Investig Med High Impact Case Rep 2017 Jan-Mar;5(1):2324709617690742. Epub 2017 Mar 28.

Division of Gastroenterology and Liver diseases, Montefiore Medical Center, The Albert Einstein College of Medicine Bronx, NY, USA.

Nodular regenerative hyperplasia (NRH) is a known etiology of noncirrhotic portal hypertension. Cases of biopsy-proven NRH in human immunodeficiency virus (HIV)-positive patients have been described. While these patients often have normal synthetic liver function, several reports described disease progression to liver failure. Read More

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http://dx.doi.org/10.1177/2324709617690742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405903PMC
March 2017
56 Reads

High-dose calcineurin inhibitor-free everolimus as a maintenance regimen for heart transplantation may be a risk factor for Pneumocystis pneumonia.

Transpl Infect Dis 2017 Aug 8;19(4). Epub 2017 Jun 8.

Division of Cardiovascular Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Background: Everolimus reduces the incidence of cardiac-allograft vasculopathy (CAV) and is less renally toxic than are calcineurin inhibitors (CNIs). We evaluated the safety of CNI-free everolimus for post-heart transplant (HTx) patients.

Methods: We retrospectively reviewed the records of 36 consecutive patients who had undergone an HTx between January 2006 and December 2013 in National Cheng Kung University Hospital. Read More

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http://dx.doi.org/10.1111/tid.12709DOI Listing
August 2017
25 Reads

Fungal infection involvement in primary biliary cirrhosis: A review of 2 cases.

Exp Ther Med 2017 Feb 16;13(2):489-494. Epub 2016 Dec 16.

Department of Rheumatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.

The present study aimed to analyze the imaging, clinical and pathological features of fungal infection involvement in primary biliary cirrhosis (PBC) by retrospectively analyzing and reviewing the features of two patients with fungal infection involvement in PBC. Both patients were female. One patient had a confirmed diagnosis of PBC. Read More

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https://www.spandidos-publications.com/10.3892/etm.2016.3977
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http://dx.doi.org/10.3892/etm.2016.3977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348652PMC
February 2017
21 Reads

Diagnosis and management of Pneumocystis jirovecii infection.

Expert Rev Anti Infect Ther 2017 05 20;15(5):435-447. Epub 2017 Mar 20.

a Public Health Wales Microbiology Cardiff, UHW , Cardiff , UK.

Introduction: Pneumocystis jirovecii is a ubiquitous fungus, which causes pneumonia in humans. Diagnosis was hampered by the inability to culture the organism, and based on microscopic examination of respiratory samples or clinical presentation. New assays can assist in the diagnosis and even aid with the emergence of resistant infections. Read More

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https://www.tandfonline.com/doi/full/10.1080/14787210.2017.1
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http://dx.doi.org/10.1080/14787210.2017.1305887DOI Listing
May 2017
25 Reads

Multiple myeloma presenting with bilateral ankle pain (microangiopathy) and complicated by streptococcal meningitis and Pneumocystis carinii pneumonia.

BMJ Case Rep 2017 Feb 7;2017. Epub 2017 Feb 7.

Department of Emergency and Intensive Care Medicine, Royal Berkshire NHS Foundation Trust, Reading, UK.

Multiple myeloma is characterised by the neoplastic proliferation of a single clone of plasma cells producing a monoclonal immunoglobulin. This clone of plasma cells proliferates in the bone marrow, resulting in extensive skeletal destruction with osteolytic lesions, osteopenia and pathological fractures. Additional disease-related complications include hypercalcaemia, renal insufficiency, anaemia and infection. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2016-21728
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http://dx.doi.org/10.1136/bcr-2016-217289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307268PMC
February 2017
45 Reads

[Life-threatening Pneumocystis pneumonia in a previously healthy pregnant woman].

Ugeskr Laeger 2017 Jan;179(3)

Pneumocystis pneumonia (PCP) is one of the most common infections in patients with HIV. Pneumocystis jirovecii rarely gives rise to symptoms in immunocompetent individuals. PCP has been reported in individuals with immunosuppression. Read More

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January 2017
4 Reads

A rare cause of cavitary lung lesions.

JAAPA 2017 Jan;30(1):28-31

Nika Pierre-Louis and Brian Dlugos were critical care physician assistants in the medical ICU at the Cleveland Clinic in Cleveland, Ohio, when this article was written. Ms. Pierre-Louis now works in the ED at CHI/St. Alexius Health in Bismarck, N.D. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Pneumocystis jirovecii pneumonia (PJP) is a common infection among susceptible patients with compromised immune function and can lead to life-threatening complications without prompt recognition and appropriate treatment. Clinicians should be aware that patients can develop severe infection even while receiving approved prophylactic medications for PJP. Furthermore, atypical radiographic findings, such as the cavitary lung lesions found in the patient in this case report, can make the diagnosis even more challenging. Read More

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http://Insights.ovid.com/crossref?an=01720610-201701000-0000
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http://dx.doi.org/10.1097/01.JAA.0000508206.48298.bcDOI Listing
January 2017
7 Reads

Clinical Course, Radiological Manifestations, and Outcome of Pneumocystis jirovecii Pneumonia in HIV Patients and Renal Transplant Recipients.

PLoS One 2016 8;11(11):e0164320. Epub 2016 Nov 8.

Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Background: Pneumocystis jirovecii pneumonia (PCP) is a frequent opportunistic infection in immunocompromised patients. In literature, presentation and outcome of PCP differs between patients with human immunodeficiency virus (HIV) infection and renal transplant recipients (RTRs).

Methods: We conducted a cross-sectional study of patients with PCP based on the HIV and renal transplant registries at our institution. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164320PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100884PMC
June 2017
46 Reads

Usefulness of Bronchoscopic Probe-Based Confocal Laser Endomicroscopy in the Diagnosis of Pneumocystis jirovecii Pneumonia.

Respiration 2016 1;92(1):40-7. Epub 2016 Jul 1.

Servei Pneumologia, Hospital Universitari Son Espases, Palma de Mallorca, Spain.

Background: Probe-based confocal laser endomicroscopy (pCLE) is a novel technique that provides in vivo microscopic imaging of the distal lung. We hypothesized that the intra-alveolar exudates characterizing Pneumocystis jirovecii pneumonia (PJP) can be identified by pCLE in vivo and help in its diagnosis.

Objectives: We aimed to assess the usefulness of pCLE for the in vivo diagnosis of PJP. Read More

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http://dx.doi.org/10.1159/000447431DOI Listing
September 2017
16 Reads
3 Citations
2.593 Impact Factor

Lenalidomide-bendamustine-rituximab in patients older than 65 years with untreated mantle cell lymphoma.

Blood 2016 10 27;128(14):1814-1820. Epub 2016 Jun 27.

Department of Oncology, Skåne University Hospital, Lund, Sweden.

For elderly patients with mantle cell lymphoma (MCL), there is no defined standard therapy. In this multicenter, open-label phase 1/2 trial, we evaluated the addition of lenalidomide (LEN) to rituximab-bendamustine (R-B) as first-line treatment for elderly patients with MCL. Patients >65 years with untreated MCL, stages II-IV were eligible for inclusion. Read More

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http://dx.doi.org/10.1182/blood-2016-03-704023DOI Listing
October 2016
25 Reads

Radiological presentation of Pneumocystis jiroveci pneumonia mimicking bacterial pneumonia.

BMJ Case Rep 2016 Jun 3;2016. Epub 2016 Jun 3.

Intensive Care Unit, Alès General Hospital, Alès, France.

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http://dx.doi.org/10.1136/bcr-2016-215207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904393PMC
June 2016
14 Reads

Chest CT for suspected pulmonary complications of oncologic therapies: how I review and report.

Authors:
Stefan Diederich

Cancer Imaging 2016 Apr 11;16. Epub 2016 Apr 11.

Department of Diagnostic and Interventional Radiology, Marien Hospital, Academic Teaching Hospital, Rochusstr. 2, D- 40479, Düsseldorf, Germany.

In cancer patient during or following oncologic therapies with respiratory symptoms and pulmonary pathology at chest CT the differential diagnosis includes infection, therapy-induced disease and tumour progression.Although CT morphology may be typical or even pathognomonic in some conditions the diagnosis is usually made by a synopsis of imaging, clinical and laboratory features.Close communication with referring colleagues and a good knowledge of potential side effects of therapeutic concepts, their time course and CT morphology is crucial in the differential diagnosis. Read More

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http://dx.doi.org/10.1186/s40644-016-0066-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828781PMC
April 2016
35 Reads

Centrilobular Cysts of the Lung.

Am J Med Sci 2016 Jan;351(1):e1

Department of Internal Medicine, Korea University Guro Hospital, Korea University Medical School, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.amjms.2015.11.001DOI Listing
January 2016
15 Reads

Loss of Virologic Control and Severe Pneumocystis pneumonia in an HIV-Infected Patient Receiving Chemotherapy for Non-Small Cell Lung Cancer.

AIDS Res Hum Retroviruses 2016 Jan 1;32(1):4-5. Epub 2015 Sep 1.

4 Institute of Human Virology and Division of Infectious Disease, University of Maryland School of Medicine , Baltimore, Maryland.

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http://www.liebertpub.com/doi/10.1089/aid.2015.0114
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http://dx.doi.org/10.1089/aid.2015.0114DOI Listing
January 2016
11 Reads

A Case of Pneumonia Caused by Pneumocystis jirovecii Resistant to Trimethoprim-Sulfamethoxazole.

Korean J Parasitol 2015 Jun 30;53(3):321-7. Epub 2015 Jun 30.

Division of Pulmonology and Allergy, Gachon University Gil Medical Center, Incheon 405-760, Korea.

A 50-year-old male visited the outpatient clinic and complained of fever, poor oral intake, and weight loss. A chest X-ray demonstrated streaky and fibrotic lesions in both lungs, and chest CT revealed multifocal peribronchial patchy ground-glass opacities with septated cystic lesions in both lungs. Cell counts in the bronchoalveolar lavage fluid revealed lymphocyte-dominant leukocytosis, and further analysis of lymphocyte subsets showed a predominance of cytotoxic T cells and few T helper cells. Read More

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http://dx.doi.org/10.3347/kjp.2015.53.3.321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510680PMC
June 2015
30 Reads

FDG PET Imaging in Pneumocystis Pneumonia.

Clin Nucl Med 2015 Aug;40(8):679-81

From the *Division of Rheumatic Diseases and †Division of Nuclear Medicine, Department of Radiology, National Center for Global Health and Medicine, Tokyo, Japan.

A 69-year-old woman with rheumatoid arthritis and pleuritis presented with dyspnea. On admission, she was afebrile and had an oxygen saturation of 97% on ambient air. Chest radiography and CT revealed only subtle ground-glass opacities. Read More

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http://pdfs.journals.lww.com/nuclearmed/2015/08000/FDG_PET_I
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/RLU.0000000000000831DOI Listing
August 2015
30 Reads

Apical Pneumocystis jiroveci as an AIDS defining illness: A case report illustrating a change in the paradigm.

J Radiol Case Rep 2014 Nov 30;8(11):15-24. Epub 2014 Nov 30.

Department of Radiology, Yale New Haven hospital, New Haven, CT, USA.

Pneumocystis jiroveci pneumonia is a common acquired immune deficiency syndrome defining illness. Pneumocystis jiroveci pneumonia is classically described as having symmetrical bilateral perihilar ground-glass opacities on chest radiographs. We present an "atypical" case of Pneumocystis jiroveci pneumonia presenting as symmetric biapical cystic spaces with relative sparing of the remainder of the lungs in a 22 year-old male, previously undiagnosed with acquired immune deficiency syndrome. Read More

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http://dx.doi.org/10.3941/jrcr.v8i11.1772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394979PMC
November 2014
20 Reads

Pathology of Sarcoidosis.

Clin Rev Allergy Immunol 2015 Aug;49(1):36-44

Department of Diagnostic Laboratories, Operative Unit of Pathologic Anatomy, Azienda Policlinico, University of Modena and Reggio Emilia, Via del Pozzo, 71-41124, Modena, Italy,

Pathologists are frequently involved in the diagnosis of sarcoidosis on conventional biopsies or examining bronchoalveolar lavage fluid and assisting bronchoscopists when performing bronchial or transbronchial biopsies or transbronchial needle aspiration (TBNA)/endobronchial ultrasound (EBUS)-guided biopsies of enlarged lymph nodes. Histology generally does not pose difficult tasks in the correct clinical and imaging scenario, but atypical forms of sarcoidosis exist, and in these cases, the diagnosis may become difficult. When faced with granulomas in the lung, the evaluation of their qualitative features, anatomic distribution, and accompanying findings usually allows the pathologist to narrow considerably the differential diagnosis. Read More

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http://dx.doi.org/10.1007/s12016-015-8479-6DOI Listing
August 2015
35 Reads

Single nodular opacity of granulomatous pneumocystis jirovecii pneumonia in an asymptomatic lymphoma patient.

Korean J Radiol 2015 Mar-Apr;16(2):440-3. Epub 2015 Feb 27.

Department of Pathology, Kyung Hee University Hospital, Seoul 130-702, Korea.

The radiologic findings of a single nodule from Pneumocystis jirovecii pneumonia (PJP) have been rarely reported. We described a case of granulomatous PJP manifesting as a solitary pulmonary nodule with a halo sign in a 69-year-old woman with diffuse large B cell lymphoma during chemotherapy. The radiologic appearance of the patient suggested an infectious lesion such as angioinvasive pulmonary aspergillosis or lymphoma involvement of the lung; however, clinical manifestations were not compatible with the diseases. Read More

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http://dx.doi.org/10.3348/kjr.2015.16.2.440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347280PMC
August 2015
27 Reads

Diagnosis of Pneumocystis pneumonia: evaluation of four serologic biomarkers.

Clin Microbiol Infect 2015 Apr 4;21(4):379.e1-10. Epub 2014 Dec 4.

Unidade de Parasitologia Médica, Grupo de Protozoários Oportunistas/VIH e Outras Protozooses-CMDT, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisboa, Portugal.

The diagnosis of Pneumocystis pneumonia (PCP) relies on microscopic visualization of Pneumocystis jirovecii organisms or DNA detection in pulmonary specimens. This study aimed to assess the usefulness of (1-3)-β-d-glucan (BG), Krebs von den Lungen-6 antigen (KL-6), lactate dehydrogenase (LDH) and S-adenosyl methionine (SAM) as serologic biomarkers in the diagnosis of PCP. Serum levels of BG, KL-6, LDH and SAM were investigated in 145 Portuguese patients, 50 patients from the Netherlands, 25 Spanish patients and 40 Portuguese blood donors. Read More

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http://dx.doi.org/10.1016/j.cmi.2014.11.025DOI Listing
April 2015
23 Reads