34,011 results match your criteria Pleural Effusion


Hepatic Hydrothorax: A Narrative Review.

Pulm Ther 2022 Jun 25. Epub 2022 Jun 25.

Department of Respiratory Medicine, Northumbria Healthcare NHS Foundation Trust, North Shields, Northumbria Way, Northumberland, Cramlington, NE23 6NZ, UK.

Hepatic hydrothorax (HH) represents a distinct clinical entity within the broader classification of pleural effusion that is associated with significant morbidity and mortality. The median survival of patients with cirrhosis who develop HH is 8-12 months. The diagnosis is typically made in the context of advanced liver disease and ascites, in the absence of underlying cardio-pulmonary pathology. Read More

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Re-expansion Pulmonary Oedema.

Interact Cardiovasc Thorac Surg 2022 Jun 25. Epub 2022 Jun 25.

Tracheal Diseases Research Center (TDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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Predicting persistent organ failure on admission in patients with acute pancreatitis: development and validation of a mobile nomogram.

HPB (Oxford) 2022 Jun 6. Epub 2022 Jun 6.

Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Center and West China-Liverpool Biomedical Research Center, West China Hospital, Sichuan University, Chengdu, China. Electronic address:

Background: Early prediction of persistent organ failure (POF) is important for triage and timely treatment of patients with acute pancreatitis (AP).

Methods: All AP patients were consecutively admitted within 48 h of symptom onset. A nomogram was developed to predict POF on admission using data from a retrospective training cohort, validated by two prospective cohorts. Read More

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Decoding the primary tumor origin in carcinomatous serous effusions by immunocytochemistry.

Cytopathology 2022 Jun 24. Epub 2022 Jun 24.

Department of Cytology and Gynecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Introduction: Malignant effusions are commonly encountered in day-to-day cytology practice. Determining the primary site of malignancy in carcinomatous effusions is a Herculean task. Cytology coupled with immunocytochemistry is often found helpful in this context. Read More

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Postoperative outcome after palliative treatment of malignant pleural effusion.

Thorac Cancer 2022 Jun 15. Epub 2022 Jun 15.

Clinic of Thoracic Surgery, Waldburg-Zeil Clinic, Wangen im Allgäu, Germany.

Background: The objective of this nationwide, registry-based study was to compare the two most frequently used procedures for the palliative treatment of a malignant pleural effusion (MPE) and to evaluate differentiated indications for these two procedures.

Methods: This was a retrospective observational study based on data of the "PLEURATUMOR" registry of the German Society for Thoracic Surgery. Patients who were documented in the period from January 2015 to November 2021 and had video-assisted thoracic surgery (VATS) talc pleurodesis or implantation of an indwelling pleural catheter (IPC) were included. Read More

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Predictive risk score of respiratory complications in children with mediastinal tumors: A case-control study.

Cancer Med 2022 Jun 23. Epub 2022 Jun 23.

Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama, Japan.

Background: The aim of this study was to examine risk factors of respiratory complications at the diagnosis and establish an algorithm of clinical management in children and adolescents with mediastinal tumors.

Methods: We retrospectively collected clinical information of all children and adolescents who presented with mediastinal tumors at Saitama Children's Medical Center from 1999 to 2019, including age, sex, pathological diagnosis, eight major clinical symptoms (cough, dyspnea, hypoxia, orthopnea, chest pain, wheeze, superior vena cava syndrome, and stridor), chest computed tomography (CT) findings (tumor location, mediastinal mass ratio, pleural fluid, pericardial effusion, and compression of trachea and bronchi), types of diagnostic procedure and anesthesia, respiratory complications (severe hypoxia, difficult ventilation, respiratory failure, and cardiopulmonary arrest), and clinical outcome. Subsequently, we calculated the risk score for predicting respiratory complications by combining clinical and radiological findings. Read More

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The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis-A 10 Year Retrospective Observational Study.

Medicina (Kaunas) 2022 May 27;58(6). Epub 2022 May 27.

Department of Thoracic Surgery, Central Military Emergency University Hospital Bucharest, University of Medicine and Pharmacy "Carol Davila", 010825 Bucharest, Romania.

Malignant neoplasms are common causes of acute pleuropericardial effusion. Pleuropericarditis denotes poor patient prognosis, is associated with shortened average survival time, and represents a surgical emergency. We analyzed the impact of two minimally invasive surgical approaches, the type of cancer, and other clinical variables on the mortality of 338 patients with pleuropericarditis admitted to an emergency hospital in Romania between 2009 and 2020. Read More

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A Rare Case of Effusive-Constrictive Pericarditis Caused by : Emergency Surgical Treatment.

Medicina (Kaunas) 2022 May 25;58(6). Epub 2022 May 25.

Adult and Pediatric Cardiac Surgery, Department of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, Italy.

A 70-year-old male patient was admitted to the emergency room in cardiac arrest. The patient was resuscitated and then referred to our cardiac surgery department, where he was diagnosed with suspected effusive constrictive pericarditis. A failed trial of TEE-guided pericardiocentesis led to the decision of surgical intervention. Read More

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Lung Sonography in Critical Care Medicine.

Diagnostics (Basel) 2022 Jun 6;12(6). Epub 2022 Jun 6.

Department of Anaesthesiology and Intensive Care Medicine, Medical University Innsbruck, 6020 Innsbruck, Austria.

During the last five decades, lung sonography has developed into a core competency of intensive care medicine. It is a highly accurate bedside tool, with clear diagnostic criteria for most causes of respiratory failure (pneumothorax, pulmonary edema, pneumonia, pulmonary embolism, chronic obstructive pulmonary disease, asthma, and pleural effusion). It helps in distinguishing a hypovolemic from a cardiogenic, obstructive, or distributive shock. Read More

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Thrombocytosis, haemorrhagic pleural effusion and fibro-infiltrative patches with cavitary lung lesions in a child with COVID-19 pneumonia.

BMJ Case Rep 2022 Jun 23;15(6). Epub 2022 Jun 23.

Pediatrics, King George's Medical University, Lucknow, Uttar Pradesh, India.

COVID-19 infection in children is relatively mild and is associated with fewer complications compared with adults. Here we report the case of a previously healthy preteen girl who presented with active COVID-19 and shock. On day 1, ultrasound of the thorax revealed a right-sided pleural effusion with haemorrhagic pus on diagnostic tap, which improved clinically with appropriate hospital treatment. Read More

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Complications After Transthoracic Needle Biopsy of Pulmonary Nodules: A Population-Level Retrospective Cohort Analysis.

J Am Coll Radiol 2022 Jun 20. Epub 2022 Jun 20.

Senior Director, Lung Cancer Initiative, Johnson & Johnson Enterprise Innovation, New Brunswick, New Jersey.

Objective: To provide recent population-based estimates of transthoracic needle biopsy (TTNB) complications and risk factors associated with these complications.

Methods: This retrospective cohort analysis included adults from a nationally representative longitudinal insurance claims data set who underwent TTNB in 2017 or 2018. Complications that were evaluated included pneumothorax, hemorrhage, and air embolism. Read More

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Multi-Disciplinary Management of Chylothorax.

Chest 2022 Jun 20. Epub 2022 Jun 20.

Interventional Pulmonology, Department of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN.

Chylothorax, the accumulation of chyle in the pleural space, is usually caused by the disruption of the thoracic duct or its tributaries. Etiologies are broadly divided into traumatic, including post-surgical, and non-traumatic, most commonly in the setting of malignancy. The management of chylothorax largely depends upon the etiology, and includes dietary modification and drainage of the pleural space. Read More

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The Treatment of Malignant Pleural Effusion With Permanent Indwelling Pleural Catheters.

Dtsch Arztebl Int 2022 Aug 22(Forthcoming). Epub 2022 Aug 22.

Background: 40 000 to 60 000 people develop malignant pleural effusion (MPE) in Germany each year. The most common causes are lung cancer and breast cancer. Patients with pleural carcinomatosis have a median survival time of four months. Read More

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Pleurisy with pneumothorax due to CAM-resistant MAC lung disease.

Respirol Case Rep 2022 Jul 14;10(7):e0993. Epub 2022 Jun 14.

Department of Respiratory Medicine Shuuwa General Hospital Saitama Japan.

A 72-year-old man received rifampicin, ethambutol and sitafloxacin to treat clarithromycin (CAM)-resistant complex (MAC) lung disease. He was admitted because of fever. Pneumothorax and pleural effusion were present in the right lung, and a new consolidation appeared in the right upper lobe. Read More

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purulent pericarditis with cardiac tamponade presenting as a complication of postobstructive pneumonia.

BMJ Case Rep 2022 Jun 22;15(6). Epub 2022 Jun 22.

Department of Cardiovascular Disease, Michigan State University, East Lansing, Michigan, USA.

A man in his 60s with stage 3 squamous cell carcinoma of the left lung status postchemotherapy and radiation therapy presented with mixed septic and obstructive shock with multiorgan dysfunction. Initial electrocardiogram showed sinus tachycardia and diffuse concaved ST elevation. Transthoracic echocardiogram revealed pericardial effusion with tamponade physiology. Read More

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Emergency open drainage of massive hemoperitoneum and early stage left hepatectomy for abdominal compartment syndrome due to hepatocellular carcinoma rupture: a case report.

Surg Case Rep 2022 Jun 22;8(1):122. Epub 2022 Jun 22.

Department of Surgery, Hyogo Prefectural Amagasaki General Medical Center, 2-17-77, Higashinaniwa, Amagasaki, Hyogo, Japan.

Background: Spontaneous rupture is one of the most life-threatening complications of hepatocellular carcinoma (HCC). Transcatheter arterial embolization (TAE) effectively achieves hemostasis in patients with hemodynamic instability. However, there have been no reports of abdominal compartment syndrome (ACS) caused by massive intra-abdominal hematoma after TAE. Read More

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Immunofluorescent and molecular characterization of effusion tumor cells reveal cancer site-of-origin and disease-driving mutations.

Cancer Cytopathol 2022 Jun 22. Epub 2022 Jun 22.

Department of Pathology, Stanford University School of Medicine, Palo Alto, California, USA.

Background: Effective cancer treatment relies on precision diagnostics. In cytology, an accurate diagnosis facilitates the determination of proper therapeutics for patients with cancer. Previously, the authors developed a multiplexed immunofluorescent panel to detect epithelial malignancies from pleural effusion specimens. Read More

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Indwelling Pleural Catheters for Refractory Hepatic Hydrothorax? A Call for Prospective Studies and Randomized Controlled Trials.

J Bronchology Interv Pulmonol 2022 07 22;29(3):161-163. Epub 2022 Jun 22.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University Health System, Richmond, VA.

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Quality of life in patients with malignant pleural effusion treated with an indwelling pleural catheter in an emerging country.

Clinics (Sao Paulo) 2022 Jun 18;77:100063. Epub 2022 Jun 18.

Instituto do Câncer do Estado de São Paulo (ICESP), Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.

Background: The use of Indwelling Pleural Catheter (IPC) in the care of patients with Malignant Pleural Effusion (MPE) is well established, however studies involving public health systems of low and middle-income countries are still lacking. This study aimed to determine the effect of IPC on the respiratory symptoms and Quality of Life (QoL) of patients with MPE in the setting of a Brazilian public health system.

Methods: From August 2015 to November 2019, patients with MPE underwent IPC placement and were prospectively followed. Read More

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Insight into diagnosis of pleural tuberculosis with special focus on nucleic acid amplification tests.

Expert Rev Respir Med 2022 Jun 21. Epub 2022 Jun 21.

Centre for Biotechnology, Maharshi Dayanand University, Rohtak-124001, India.

Introduction: Pleural tuberculosis (TB) is the archetype of extrapulmonary TB (EPTB), which mainly affects the pleural space and leads to exudative pleural effusion. Diagnosis of pleural TB is a difficult task predominantly due to atypical clinical presentations and sparse bacillary load in clinical specimens.

Area Covered: We reviewed the current literature on the globally existing conventional/latest modalities for diagnosing pleural TB. Read More

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Hyperthyroidism due to thyrotropin receptor antibody stimulation of metastatic thyroid carcinoma during lenvatinib treatment: a case report.

Ann Palliat Med 2022 Jun 20. Epub 2022 Jun 20.

Department of Breast and Endocrine Surgery, Kanagawa Cancer Center, Yokohama, Japan.

Background: Hyperthyroidism after total thyroidectomy is extremely rare. No studies have investigated hyperthyroidism during multiple kinase inhibitor treatment for advanced thyroid carcinoma.

Case Description: A 57-year-old man with a history of radioactive iodine refracted thyroid follicular carcinoma presented to our hospital with back pain. Read More

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Post-PRRT scans: which scans to make and what to look for.

Cancer Imaging 2022 Jun 17;22(1):29. Epub 2022 Jun 17.

Department of Nuclear Medicine, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands.

Aim: The aim of this study was to evaluate the clinical utility of SPECT/CT (imaging of uptake in tumor lesions and additional findings) and the additional value of planar imaging in order to simplify clinical imaging protocols and decrease patients burden.

Materials And Methods: One hundred consecutive patients with metastatic neuroendocrine tumor (NET) treated with PRRT were included. Post-therapy imaging was performed 24 h after each PRRT cycle by both whole-body planar imaging and abdominal- and thoracic SPECT/CT. Read More

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Diagnostic performance of artificial intelligence approved for adults for the interpretation of pediatric chest radiographs.

Sci Rep 2022 Jun 17;12(1):10215. Epub 2022 Jun 17.

Department of Radiology, Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yongin Severance Hospital, Yonsei University College of Medicine, 363, Dongbaekjukjeon-daero, Giheung-gu, Yongin-si, Gyeonggi-do, 16995, Republic of Korea.

Artificial intelligence (AI) applied to pediatric chest radiographs are yet scarce. This study evaluated whether AI-based software developed for adult chest radiographs can be used for pediatric chest radiographs. Pediatric patients (≤ 18 years old) who underwent chest radiographs from March to May 2021 were included retrospectively. Read More

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Electrolyte analysis of pleural effusion for discrimination between seawater and freshwater drowning in decomposed bodies.

J Forensic Leg Med 2022 Jun 8;90:102389. Epub 2022 Jun 8.

Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan; Education and Research Center of Legal Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan. Electronic address:

Objective: The diagnosis of drowning is an important issue in forensic investigations. Moreover, discriminating between seawater and freshwater drowning is crucial to identify where the drowning occurred. The present study aimed to investigate electrolyte concentrations in pleural fluid in decomposed bodies in late postmortem intervals and derive cut-off values for the diagnosis of seawater and freshwater drowning. Read More

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Clinical Characteristics of Chlamydia psittaci Pneumonia Infection in Central South China.

Infect Dis Ther 2022 Jun 20. Epub 2022 Jun 20.

Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.

Introduction: Chlamydia psittaci pneumonia has been a global public health hotspot in recent years. Although some scattered cases of C. psittaci pneumonia have been reported, there is a lack of large case studies worldwide. Read More

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mutation landscape in non-small cell lung cancer patients in Northeast China.

Tumori 2022 Jun 19:3008916221101426. Epub 2022 Jun 19.

Translational Oncology Research Lab, Jilin Cancer Hospital, Changchun, China.

Objective: This study aimed to explore erb-b2 receptor tyrosine kinase 2 () gene mutations in patients with non-small cell lung cancers (NSCLC) in Northeast China, and to analyze mutation subtypes and clinicopathological characteristics related to the presence of mutations.

Methods: In this study, 1087 tissue samples, 368 whole blood samples, and 68 pleural effusion samples from 1349 NSCLC were collected. Next-generation sequencing (NGS) was used to perform genetic testing on the samples. Read More

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An Unusual Cause of Right Heart Failure: Hemorrhagic Pericardial Cyst Presenting as a Pericardial Mass and Constrictive Pericarditis.

Indian J Radiol Imaging 2022 Mar 19;32(1):132-135. Epub 2022 Apr 19.

Department of Thoracic and vascular Surgery, Government Medical College Hospital, Thiruvananthapuram, Kerala, India.

Congenital pericardial cysts are very rare neoplasms of the middle mediastinum. We report a case of a young woman who was referred to the surgical department with abdominal pain. The ultrasound done showed moderate ascites and pleural effusion. Read More

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The efficacy of Endostar combined with platinum pleural infusion for malignant pleural effusion in tumor patients is significantly better than that of monotherapy, but the economy is lower: a systematic review, network meta-analysis and cost-effectiveness analysis.

Ann Transl Med 2022 May;10(10):604

School of Pharmacy Anhui Medical University, Hefei, China.

Background: Endostar and platinum were widely used in the treatment of malignant pleural effusion (MPE), but there was no unified conclusion on which scheme is the best. The aim of this study was to systematically evaluate the efficacy and cost-effectiveness of Endostar, cisplatin, lobaplatin, Endostar combined with cisplatin, and Endostar combined with lobaplatin in the treatment of MPE so as to provide a reference for clinical treatment.

Methods: A comprehensive literature search was performed of sources on PubMed, Web of Science, and other databases published up to and including November 23, 2021, and screened out randomized controlled trial (RCT) concerning the efficacy of 5 interventions of pleural perfusion for MPE. Read More

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Detection and Significance of Cell-Free DNA Mutation in Pleural Effusion in Patients with Advanced NSCLC.

Emerg Med Int 2022 10;2022:3112281. Epub 2022 Jun 10.

Department of Respiratory Medicine, Tianjin Hospital of ITCWM, Nankai Hospital, Tianjin 300100, China.

Objective: To detect EGFR/KRAS genes in pleural effusion cell-free DNA in patients with advanced non-small-cell lung cancer (NSCLC) and to explore the clinical significance of EGFR/KRAS mutation status in pleural effusion.

Methods: A retrospective collection was performed on the specimens of pleural effusion and matched tissues from 50 patients with advanced NSCLC admitted to the hospital between January 2019 and January 2021. DNA mutation status of EGFR/KRAS in different specimens was detected and compared by pyrosequencing. Read More

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