79,076 results match your criteria Pleural Effusion


Exploring the Clinical Utility of Metagenomic Next-Generation Sequencing in the Diagnosis of Pulmonary Infection.

Infect Dis Ther 2021 Jun 12. Epub 2021 Jun 12.

Department of Respiratory, The Affiliated Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, China.

Introduction: We aimed to explore the real-world clinical application value and challenges of metagenomic next-generation sequencing (mNGS) for pulmonary infection diagnosis.

Methods: We retrospectively reviewed the results of mNGS and conventional tests from 140 hospitalized patients with suspected pulmonary infections from January 2019 to December 2020. The sample types included bronchoalveolar lavage fluid, lung tissue by transbronchial lung biopsy, pleural effusion, blood, and bronchial sputum. Read More

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3 Tesla MRI in diagnosis and follow up of children with pneumonia.

Clin Imaging 2021 Jun 1;79:213-218. Epub 2021 Jun 1.

Ondokuz Mayis University Faculty of Medicine, Department of Biostatistics and Medical Informatics, Samsun, Turkey.

Purpose: To investigate the utilization of 3-Tesla (3 T) magnetic resonance imaging (MRI) in detection of pulmonary abnormalities in children with pneumonia.

Materials And Methods: Forty-seven children with pneumonia prospectively underwent 3 T thoracic MRI and posteroanterior (PA) chest radiography (CR). Of these, 15 patients also underwent contrast-enhanced thorax computed tomography (CT) or high-resolution CT (HRCT). Read More

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SERUM PROTEOMICS AND PLASMA FIBULIN-3 IN DIFFERENTIATION OF MESOTHELIOMA FROM ASBESTOS-EXPOSED CONTROLS AND PATIENTS WITH OTHER PLEURAL DISEASES.

J Thorac Oncol 2021 Jun 8. Epub 2021 Jun 8.

Cancer Research UK Beatson Institute, Glasgow, UK.

Introduction: Malignant pleural mesothelioma (MPM) is difficult to diagnose. An accurate blood biomarker could prompt specialist referral or be deployed in future screening. In earlier retrospective studies, SOMAscan® proteomics and Fibulin-3 appeared highly accurate, but SOMAscan® has not been validated prospectively and subsequent Fibulin-3 data have been contradictory. Read More

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Tim-4 cavity-resident macrophages impair anti-tumor CD8 T cell immunity.

Cancer Cell 2021 May 29. Epub 2021 May 29.

Departments of Surgery and Pathology, Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA.

Immune checkpoint blockade (ICB) has been a remarkable clinical advance for cancer; however, the majority of patients do not respond to ICB therapy. We show that metastatic disease in the pleural and peritoneal cavities is associated with poor clinical outcomes after ICB therapy. Cavity-resident macrophages express high levels of Tim-4, a receptor for phosphatidylserine (PS), and this is associated with reduced numbers of CD8 T cells with tumor-reactive features in pleural effusions and peritoneal ascites from patients with cancer. Read More

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Ovarian dysgerminoma with pseudo-Meigs syndrome: A case report.

Medicine (Baltimore) 2021 Jun;100(23):e26319

Forensic and Pathology Laboratory, Jiaxing University Medical College, Jiaxing, ZJ, China.

Rationale: Dysgerminoma is a rare malignant tumor of the ovary, more frequently occurring in young women. The main signs of pseudo-Meigs syndrome (PMS) are ascites and hydrothorax accompanying benign or malignant ovarian tumors (no fibroma or fibroma-like tumor).

Patient Concerns: A 19-year-old woman with fever and chest tightness for 2 days. Read More

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Technology development of hyperthermic pressurized intraperitoneal aerosol chemotherapy (hPIPAC).

Surg Endosc 2021 Jun 10. Epub 2021 Jun 10.

Department of General and Transplant Surgery and National Center for Pleura and Peritoneum, University of Tübingen, Tübingen, Germany.

Background: Optimized drug delivery systems are needed for intraperitoneal chemotherapy. The aim of this study was to develop a technology for applying pressurized intraperitoneal aerosol chemotherapy (PIPAC) under hyperthermic conditions (hPIPAC).

Methods: This is an ex-vivo study in an inverted bovine urinary bladder (IBUB). Read More

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Lung Ultrasound Score as a Predictor of Mortality in Patients With COVID-19.

Front Cardiovasc Med 2021 25;8:633539. Epub 2021 May 25.

Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Lung injury is a common condition among hospitalized patients with coronavirus disease 2019 (COVID-19). However, whether lung ultrasound (LUS) score predicts all-cause mortality in patients with COVID-19 is unknown. The aim of the present study was to explore the predictive value of lung ultrasound score for mortality in patients with COVID-19. Read More

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Cardiac Tamponade Unmasking Recurrent Ovarian Cancer.

Cureus 2021 Jun 5;13(6):e15464. Epub 2021 Jun 5.

Gynecologic Oncology, State University of New York (SUNY) Downstate Medical Center, Brooklyn, USA.

Pericardial disease is a common manifestation of malignancy. Gynecologic malignancies such as ovarian cancer rarely present with cardiac involvement. Cardiac tamponade may be the initial presentation of malignancy in as many as half of pericardial disease cases. Read More

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Acute Pancreatitis with an Ongoing Pancreatic Duct Leak Complicated by Refractory Pleural Effusion: A Case Report.

Am J Case Rep 2021 Jun 11;22:e931330. Epub 2021 Jun 11.

Department of Gastroenterology, Community Memorial Health Systems, Ventura, CA, USA.

BACKGROUND Acute pancreatitis causes a significant systemic inflammatory response that affects multiple organs. Pulmonary complications include pleural effusions, hypoxia, atelectasis, and acute respiratory distress syndrome. Pleural effusion is an indicator of poor prognosis in pancreatitis. Read More

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Patient and hospital factors associated with 30-day readmissions after coronary artery bypass graft (CABG) surgery: a systematic review and meta-analysis.

J Cardiothorac Surg 2021 Jun 10;16(1):172. Epub 2021 Jun 10.

Centre for Big Data Research in Health, University of New South Wales (UNSW) Sydney, Kensington, Australia.

Background: Readmission after coronary artery bypass graft (CABG) surgery is associated with adverse outcomes and significant healthcare costs, and 30-day readmission rate is considered as a key indicator of the quality of care. This study aims to: quantify rates of readmission within 30 days of CABG surgery; explore the causes of readmissions; and investigate how patient- and hospital-level factors influence readmission.

Methods: We conducted systematic searches (until June 2020) of PubMed and Embase databases to retrieve observational studies that investigated readmission after CABG. Read More

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The diagnostic value of CEA for lung cancer-related malignant pleural effusion in China: A Meta-analysis.

Expert Rev Respir Med 2021 Jun 10. Epub 2021 Jun 10.

Department of Pathology, Jiangdu people's Hospital Affiliated to Medical College of Yangzhou University, Yangzhou, Jiangsu, China.

: To accurately evaluate the diagnostic value of carcinoembryonic antigen (CEA) for malignant pleural effusion associated with lung cancer in Chinese population. : Three English databases, PubMed, Embase and Web of Science, and two Chinese databases, China National Knowledge Infrastructure (CNKI) and Wanfang Data, up to November 5, 2020, were searched. The literatures on the diagnosis of lung cancer-related malignant pleural effusion by CEA in Chinese population were collected. Read More

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A rapid calprotectin test for the diagnosis of pleural effusion.

PLoS One 2021 10;16(6):e0252714. Epub 2021 Jun 10.

Grupo de Investigación en Química Coloidal, Instituto de Investigación Sanitaria Galicia Sur (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain.

In previous studies, measuring the levels of calprotectin in patients with pleural effusion (PE) was an exceptionally accurate way to predict malignancy. Here, we evaluated a rapid method for the measurement of calprotectin levels as a useful parameter in the diagnosis of malignant pleural effusion (MPE) in order to minimise invasive diagnostic tests. Calprotectin levels were measured with Quantum Blue® sCAL (QB®sCAL) and compared with the gold standard reference ELISA method. Read More

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CT appearances, patterns of progression, and follow-up of COVID-19: evaluation on thin-section CT.

Insights Imaging 2021 Jun 10;12(1):73. Epub 2021 Jun 10.

Department of Radiology, Beijing Ditan Hospital, Capital Medical University, No. 8 Jingshun East Street, Chaoyang District, Beijing, China.

Background: To retrospectively analyze CT appearances and progression pattern of COVID-19 during hospitalization, and analyze imaging findings of follow-up on thin-section CT.

Methods: CT findings of 69 patients with COVID-19 were evaluated on initial CT, peak CT, and pre-discharge CT. CT pattern were divided into four types on CT progression. Read More

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Expanding mutational spectrum of HRAS by a patient with Schimmelpenning-Feuerstein-Mims syndrome.

J Dermatol 2021 Jun 9. Epub 2021 Jun 9.

Department of Pediatric Hematology-Oncology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

As one of the epidermal nevus syndromes, Schimmelpenning-Feuerstein-Mims (SFM) is characterized by craniofacial nevus sebaceous (NS) and extracutaneous abnormalities (e.g., brain, eyes, and bone). Read More

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Predictive power of modified frailty index score for pulmonary complications after major abdominal surgery in the elderly: a single centre prospective cohort study.

Eur Rev Med Pharmacol Sci 2021 May;25(10):3798-3802

Dipartimento di Scienze dell'Emergenza, Anestesiologiche e della Rianimazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Objective: The primary aim of this prospective cohort study was to evaluate the usefulness of the modified Frailty Index (mFI) score to predict postoperative pulmonary complications (PPCs) in elderly patients undergoing major open abdominal surgery. The secondary purpose was to compare the prediction power of mFI, Ariscat (Assess Respiratory Risk in Surgical Patients in Catalonia), and American Society physical status classification (ASA) scores.

Patients And Methods: After local Ethical Committee approval, 105 patients aged ≥65 years undergoing open major abdominal surgery were enrolled. Read More

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Development and Validation of a Combined Model for Preoperative Prediction of Lymph Node Metastasis in Peripheral Lung Adenocarcinoma.

Front Oncol 2021 24;11:675877. Epub 2021 May 24.

Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Background: Based on the "seed and soil" theory proposed by previous studies, we aimed to develop and validate a combined model of machine learning for predicting lymph node metastasis (LNM) in patients with peripheral lung adenocarcinoma (PLADC).

Methods: Radiomics models were developed in a primary cohort of 390 patients (training cohort) with pathologically confirmed PLADC from January 2016 to August 2018. The patients were divided into the LNM (-) and LNM (+) groups. Read More

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Extreme bradycardia as presentation of an eating disorder.

BMJ Case Rep 2021 Jun 9;14(6). Epub 2021 Jun 9.

Cardiovascular Research Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

We present a case of extreme bradycardia in an 18-year-old man, accompanied by bilateral pleural effusions, pericardial effusion, endocrine dysregulation and Horner's syndrome. Despite extensive investigations as an inpatient and multidisciplinary input, it was not until subsequent assessment by an endocrine team that it was revealed that his presentation was attributable to an eating disorder. Following dietary advice, easing of extreme exercise and continued support, the patient improved in all parameters including body mass index and he remains well. Read More

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EGFR-mutant NSCLC presenting with stroke and massive systemic embolization as the first manifestation: case report.

BMC Neurol 2021 Jun 9;21(1):221. Epub 2021 Jun 9.

Department of Neurology, The Second Hospital of Hebei Medical University, 309 Zhonghuabei Street, Hebei, 050000, Shijiazhuang, People's Republic of China.

Background: Presentation with massive systemic embolization as the initial manifestation of occult malignancy is infrequent. The standard management of cancer-related arterial thromboembolism has not yet been established.

Case Presentation: We described a case of Trousseau's syndrome resulting in acute ischemic stroke concomitant with multiple embolizations in the spleen and kidney during oral administration of dabigatran for pulmonary embolism preceding the diagnosis of a malignant tumor. Read More

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[CME Sonography 98: Chest Ultrasound].

Praxis (Bern 1994) 2021 Jun;110(8):453-459

Ultrasound Learning Center (ULC) der European Federation of Ultrasound in Medicine and Biology (EFSUMB), Klinik Hirslanden, Zürich.

CME Sonography 98: Chest Ultrasound Chest sonography has long been an important part of ultrasound diagnostics. Historically, the first evidence found in chest sonography were pleural effusions. Peripheral consolidations (pneumonia, tumors, pulmonary embolism) and pneumothorax were added later. Read More

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[POCUS - Thoracic Sonography in Times of Corona: What Sonographing Family Physicians Should Examine].

Praxis (Bern 1994) 2021 Jun;110(8):439-448

Rankweil, Österreich.

POCUS - Thoracic Sonography in Times of Corona: What Sonographing Family Physicians Should Examine When performing chest sonography of patients with symptoms such as respiratory infection, dyspnea and chest pain, the primary goal is to find or exclude significant diagnoses such as pneumothorax, pleural effusion, pulmonary edema, tumors, pulmonary emboli, etc. as the cause of the symptoms. If infection with SARS-CoV-2 is present, COVID-19 pneumonia can be confirmed or excluded as the cause of the symptoms with a high degree of probability based on the sonographic signs. Read More

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Clinical course of asymptomatic malignant pleural effusion in non-small cell lung cancer patients: A multicenter retrospective study.

Medicine (Baltimore) 2021 May;100(19):e25748

Department of Internal Medicine.

Abstract: The British Thoracic Society guidelines recommend observation for patients with asymptomatic malignant pleural effusion (MPE). However, asymptomatic MPE can become symptomatic. This study examined the clinical course of asymptomatic MPE in patients with non-small cell lung cancer (NSCLC), including the incidence and timing of symptom development of asymptomatic MPE and the associated factors. Read More

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Immune Checkpoint Inhibition for Unresectable Malignant Pleural Mesothelioma.

Drugs 2021 Jun 9. Epub 2021 Jun 9.

Lung Unit, Department of Medicine, Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.

Immune checkpoint inhibitors (ICI) have shown important but variable efficacy in mesothelioma despite a lack of strong biological rationale. Initial trials assessed ICI monotherapy in patients with relapsed mesothelioma, with objective response rates (ORR) between 4.5 and 29%, median progression-free survival (PFS) between 2. Read More

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Pulmonary and thoracic infection by Fusobacterium nucleatum.

Andes Pediatr 2021 Feb 22;92(1):93-98. Epub 2021 Feb 22.

Hospital Dr. Gustavo Fricke, Valparaíso, Chile.

Introduction: Fusobacterium nucleatum is an anaerobic bacillus that is part of the oral microbiota and dental pla que. This can cause local and potentially remote infections, which are exceptional in pediatrics. Ob jective: To present the case of a patient with lung injury with chest wall invasion by Fusobacterium nucleatum. Read More

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February 2021

Relationship Between Chest Computed Tomography Findings and Clinical Conditions of Coronavirus Disease (COVID-19): A Multicentre Experience.

Int J Clin Pract 2021 Jun 9:e14459. Epub 2021 Jun 9.

Gazi University, Medical Faculty Department of Medical Microbiology, Division of Medical Virology Ankara, Turkey.

Aims: This study aimed to investigate the clinical and chest computed tomography (CT) features associated with clinical parameters for coronavirus disease (COVID-19) in the capital of Turkey, Ankara.

Materials And Methods: Epidemiological, clinical features, laboratory findings and radiological characteristics of 1,563 hospitalised patients with COVID-19 in Ankara were collected, reviewed and analysed in this study. The risk factors associated with disease severity were investigated. Read More

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Preoperative Lung Ultrasound to Detect Pleural Adhesions: A Systematic Review and Meta-Analysis.

Cureus 2021 May 6;13(5):e14866. Epub 2021 May 6.

Hospital Care Research Unit, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, JPN.

The usage of lung ultrasound as a preoperative examination for thoracic surgeries remains controversial. Our systematic review and meta-analysis aimed to evaluate preoperative lung ultrasound diagnostic accuracy for detecting pleural adhesions. We searched articles published in MEDLINE, Embase, CENTRAL, and the International Clinical Trials Registry Platform until October 2020. Read More

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Outside the Thorax: Doege-Potter Syndrome Presenting as a Retroperitoneal Abdominal Mass.

Case Rep Endocrinol 2021 19;2021:9919321. Epub 2021 May 19.

Department of Endocrinology, Department of Medicine, West Virginia University, Morgantown, WV, USA.

Objective: We present a case of refractory hypoglycemia, weight loss, and retroperitoneal solitary fibrous tumor. . A 68-year-old female presented with symptomatic hypoglycemia, weight loss, and abdominal mass identified on CT scan of the abdomen. Read More

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Preoperative prediction of the localization of a solitary fibrous tumor using four-dimensional computed tomography: a case report.

J Surg Case Rep 2021 Jun 5;2021(6):rjab184. Epub 2021 Jun 5.

Department of Pathology, Japanese Red Cross Society Nagano Hospital, Nagano, Nagano, Japan.

Solitary fibrous tumors of the pleura (SFTP) are relatively rare primary pleural tumors. Four-dimensional computed tomography (4D-CT) is reportedly useful in assessing parietal pleural invasion and adhesion in patients with lung cancer. We report a case in which 4D-CT was performed to evaluate SFTP localization and parietal pleural invasion and adhesions. Read More

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[Chemotherapy for breast cancer during pregnancy: about a case].

Pan Afr Med J 2021 11;38:255. Epub 2021 Mar 11.

Faculté de Médecine d'Antananarivo, Antananarivo, Madagascar.

The management of breast cancer during pregnancy is a challenge for physicians due to mother´s desire to carry the pregnancy to term despite the need for chemotherapy. This study reports the case of a 37-year-old multiparous woman at 20 weeks and 4 days of amenorrhea (WA). She was hospitalized for dyspnoea (stage IV according to New York Heart Association (NYHA) classification). Read More

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