5,942 results match your criteria Pleomorphic Adenoma


Necrotizing sialometaplasia can hide the presence of salivary gland tumors. A case series.

Oral Dis 2019 Feb 18. Epub 2019 Feb 18.

Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

Objective: Necrotizing sialometaplasia (NS) is an uncommon benign process which affects minor and, more rarely, major salivary glands. While self-limiting, the condition might be clinically and histologically mistaken for malignancy. Furthermore, NS may accompany neoplasms. Read More

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http://dx.doi.org/10.1111/odi.13066DOI Listing
February 2019

Two case reports of synchronous unilateral pleomorphic adenoma and cystadenolymphoma of the parotid gland with literature review.

J Ultrason 2018 ;18(75):369-373

Department of Otorhinolaryngology, Head and Neck Surgery , Klinikum Augsburg, Augsburg , Germany.

Synchronous unilateral tumors in the parotid glands account for less than 5-10% of all salivary gland neoplasms. Mostly these are cystadenolymphomas, but tumors of different histological types can be found as well. In these cases it is often pleomorphic adenoma in combination with cystadenolymphoma. Read More

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http://dx.doi.org/10.15557/JoU.2018.0055DOI Listing
January 2018

Transoral robotic surgery for the parapharyngeal space: expanding the transoral corridor.

J Robot Surg 2019 Feb 14. Epub 2019 Feb 14.

Department of Otolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, Teaching Block, 4th, Floor, New Delhi, 110029, India.

To analyze the feasibility, surgical outcomes and possible risks and complications encountered during transoral robotic surgery (TORS) for approaching parapharyngeal space (PPS) tumours, a retrospective cohort study was conducted. Out of 108 TORS procedures performed, 5 PPS tumours were identified from May 2011- November 2017. This study included 2 retrostyloid (benign nerve sheath tumour) and 3 prestyloid tumours (pleomorphic adenoma), of which one patient had previously undergone a transcervical approach for deep lobe of parotid pleomorphic adenoma. Read More

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http://dx.doi.org/10.1007/s11701-019-00932-3DOI Listing
February 2019

Collagenous crystalloids in pleomorphic adenoma of the parotid gland.

Diagn Cytopathol 2019 Feb 12. Epub 2019 Feb 12.

Department of Pathology and Laboratory Medicine, Kansai Medical University, Osaka, Japan.

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http://dx.doi.org/10.1002/dc.24149DOI Listing
February 2019

Extracapsular invasion: A potential prognostic marker for Carcinoma ex-pleomorphic adenoma of the salivary glands? A Systematic Review.

J Oral Pathol Med 2019 Feb 13. Epub 2019 Feb 13.

Department of Oral Pathology, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.

Background: The aim of the present study was to integrate available data published in the literature on extracapsular invasion in cases of CXPA that correlated findings with the prognosis of analysed patients.

Methods: An electronic search was carried out at the MEDLINE/PubMed, EMBASE and Cochrane Collaboration Library databases. Articles that assessed the relationship between extracapsular invasion and survival of patients diagnosed with CXPA were selected for the systematic review. Read More

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http://dx.doi.org/10.1111/jop.12841DOI Listing
February 2019

[Epithelial tumors of salivary glands. Review of 286 pathology reports].

Rev Med Chil 2018 Dec;146(10):1159-1166

Departamento de Anatomía Patológica, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Background: Epithelial tumors of the salivary glands, including benign tumors and aggressive malignancies with different prognoses, are uncommon.

Aim: To describe the frequency and distribution of salivary gland tumors according to age, gender and anatomical location.

Material And Methods: Review of pathological reports of salivary gland tumors of a Pathology laboratory at a clinical hospital from 2006 to 2016. Read More

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http://dx.doi.org/10.4067/S0034-98872018001001159DOI Listing
December 2018
2 Reads

A case of minor salivary gland sialolithiasis of the upper lip.

Oral Maxillofac Surg 2019 Feb 5. Epub 2019 Feb 5.

Department of Oral and Maxillofacial Surgery, Nagoya Ekisaikai Hospital, 4-66 Syounen-cho, Nakagawa-ku, Nagoya, 454-8502, Japan.

Background: Sialolithiasis is the most common disease of the salivary glands. Sialolithiasis usually develops in the major salivary glands, and rarely in the minor salivary glands, with only 2% of all cases of sialolithiasis occurring in the minor salivary glands and sublingual glands. Sialoliths in the minor salivary glands result in few or no clinical symptoms and are seldom identified on imaging. Read More

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http://dx.doi.org/10.1007/s10006-019-00745-6DOI Listing
February 2019
1 Read

Intraductal pseudopodia in pleomorphic adenoma of parotid gland.

Indian J Pathol Microbiol 2019 Jan-Mar;62(1):117-118

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Pleomorphic adenoma is the most common salivary gland tumor. Pseudopodia are finger-like projections extending beyond the tumor capsule, seen in pleomorphic adenoma. If not resected completely, these pseudopodia may increase the risk of recurrence after excision of pleomorphic adenoma. Read More

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http://dx.doi.org/10.4103/IJPM.IJPM_307_17DOI Listing
February 2019
2 Reads

Immunohistochemical evaluation of salivary gland tumors differentiation and proliferation by using calponin and telomerase.

Saudi Dent J 2019 Jan 29;31(1):105-114. Epub 2018 Nov 29.

Technical College of Health-Sulaimani Polytechnic University, Iraq.

Background: Salivary gland tumors are a heterogeneous group of lesions with diverse histological features. Hence they are considered as a diagnostic challenge for the pathologist. Myoepithelial cells are considered as a key in the morphogenetic process, with diverse differentiation in various salivary gland tumors. Read More

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http://dx.doi.org/10.1016/j.sdentj.2018.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349947PMC
January 2019
2 Reads

Intraparotid facial nerve schwannomas.

Arch Craniofac Surg 2019 Feb 1. Epub 2019 Feb 1.

Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea.

Schwannoma is a benign tumor rarely found in the head and neck and much less commonly found in the intraparotid facial nerve. It is a slow-growing encapsulated tumor originating from the Schwann cells or axonal nerve sheath. It can occur anywhere along the course of the facial nerve. Read More

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http://dx.doi.org/10.7181/acfs.2018.02250DOI Listing
February 2019
2 Reads

Ectopic pleomorphic adenoma on subcutaneous plane of the cheek.

Arch Craniofac Surg 2019 Feb 1. Epub 2019 Feb 1.

Department of Plastic and Reconstructive Surgery, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.

Pleomorphic adenoma is the most common benign tumor of the salivary gland. Pleomorphic adenoma occurs most commonly in the parotid gland but it may involve other salivary gland such as submandible or lingual. We report an ectopic pleomorphic adenoma in the subcutaneous layer of the face. Read More

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http://e-acfs.org/journal/view.php?doi=10.7181/acfs.2018.019
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http://dx.doi.org/10.7181/acfs.2018.01949DOI Listing
February 2019
5 Reads

[Clinical analysis and surgical treatment evaluation of 23 cases with primary parapharyngeal space tumors].

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Feb;54(2):107-111

Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China.

To analyze the clinical characters and surgical treatment of primary parapharyngeal space (PPS) tumors. A total of 23 cases of primary PPS tumors which were treated from November 2011 to December 2017 were included for the retrospective analysis in this study. Twenty-three cases of patients with primary PPS tumors were analyzed in this study. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1002-0098.2019.02.006DOI Listing
February 2019
1 Read

[Hepatic metastasis of a pleomorphic adenoma].

Medicina (B Aires) 2019 ;79(1):64-66

Servicio de Cirugía General, Hospital Alemán, Buenos Aires, Argentina.

Pleomorphic adenoma is the most benign tumor of the salivary glands. It can undergo a malignant transformation to carcinoma and metastasize to distant organs, sometimes it can metastasize as a benign tumor. We present the case of an 82 years old male with hepatic lesion detected by ultrasound in routine urologic follow-up. Read More

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January 2019
5 Reads

Oncocytoma Parotid Gland.

Ann Maxillofac Surg 2018 Jul-Dec;8(2):330-332

Department of ENT, Base Hospital Delhi Cantt, New Delhi, India.

Very few cases of parotid oncocytoma have been reported in literature. Because of its rarity (<1% of salivary gland tumors) and clinical presentation of the tumor, there is a tendency among the clinicians to misdiagnose it as pleomorphic adenoma, hemangioma, or other forms of oncocytosis. Only a histopathological examination can confirm it. Read More

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http://dx.doi.org/10.4103/ams.ams_154_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327801PMC
January 2019
1 Read

Nasopharyngeal Pleomorphic Adenoma: A Rare Case Report and Review of the Literature.

Case Rep Otolaryngol 2018 31;2018:2481370. Epub 2018 Dec 31.

Istanbul Medeniyet University, Faculty of Medicine, Department of Otorhinolaryngology, Goztepe Training and Research Hospital, Istanbul, Turkey.

Salivary gland tumors are rare among all head and neck tumors. Pleomorphic adenoma (PA) is the most commonly seen subtype, and 85% of the cases are located in the parotid gland. PA may very rarely be seen in minor salivary glands. Read More

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http://dx.doi.org/10.1155/2018/2481370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332957PMC
December 2018
1 Read

[Surgery of primary tracheal tumours of the salivary gland type].

Rev Mal Respir 2019 Jan 25. Epub 2019 Jan 25.

Service de chirurgie thoracique, CHU Hassan II, BP. 1893, Km 2.200, route de Sidi Harazem, 30000 Fès, Maroc; Faculté de médecine et de pharmacie, université Sidi Mohamed Ben Abdellah, Fès, Maroc.

Introduction: Primary tumours of the trachea are very rare and may develop from the tracheal salivary glands.

Case Reports: We describe four patients operated on in our service between 2010 and 2017 of whom two had an adenocystic carcinoma, one a mucoepidermoid carcinoma and one a pleomorphic adenoma of the trachea. All were treated by resection and tracheal anastomosis with clear margins in three cases. Read More

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http://dx.doi.org/10.1016/j.rmr.2019.01.001DOI Listing
January 2019
1 Read

Trastuzumab-Based Combination Chemotherapy in Patients with Human Epidermal Growth Factor Receptor-2-Positive Metastatic Carcinoma ex Pleomorphic Adenoma.

Case Rep Oncol 2018 Sep-Dec;11(3):835-841. Epub 2018 Dec 11.

Department of Medical Oncology, Sapporo Medical University, Sapporo, Japan.

Background: Carcinoma ex pleomorphic adenoma (CXPA) is a rare histologic subtype of lacrimal gland and submandibular gland cancer. Currently, there is no standard treatment for metastatic CXPA, although some case reports have explored the role of targeted agents in chemotherapy. A few histopathologic analyses have shown that some of these tumors overexpress human epidermal growth factor receptor-2 (HER2), suggesting a potential role for HER2-based therapy. Read More

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http://dx.doi.org/10.1159/000495344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341428PMC
December 2018
2 Reads

An Unusual Variant of a Common Palatal Salivary Gland Tumor: Case Report of a Pleomorphic Adenoma with Significant Lipomatous Metaplasia.

Case Rep Dent 2018 25;2018:2052347. Epub 2018 Dec 25.

New York University College of Dentistry, 345 E 24th St, Room 837, NY, New York 10010, USA.

Introduction: Salivary gland tumors are relatively common in the junction of the hard and soft palate area of the oral cavity. Pleomorphic adenoma is considered the most common benign salivary gland tumor in this location. Some of the rarer subtypes of this tumor may have a misleading clinical presentation. Read More

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http://dx.doi.org/10.1155/2018/2052347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323424PMC
December 2018
2 Reads

[First bite syndrome after parapharyngeal space tumor surgery:two cases report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Jan;33(1):81-84

Ten patients with parapharyngeal space tumor, all underwent surgery, which of two cases concurrent FBS,analyze its clinical characteristics and review the related literatures. Two cases complicated with FBS, both with primary healing of incision, the pathological diagnosis are pleomorphic adenoma and schwannoglioma respectively, both give non-steroidal anti-inflammatory drugs, paregoric and anticonvulsants, followed up for nine months and 16 months respectively, both two cases partial relief. FBS is one of surgical complications of parapharyngeal space,which should not be neglected by physicians. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.01.018DOI Listing
January 2019
1 Read

Potential immmunohistochemical markers to characterize epithelial-mesenchymal transition in pleomorphic adenoma.

J Exp Ther Oncol 2019 Jan;13(1):1-7

Department of Oral Surgery, Pt. B. D Sharma University of Health Sciences, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India.

Backgound: The histogenesis process of pleomorphic adenoma (PA) of salivary gland continues to remain a controversial subject. In this neoplasm, transition occurs from an epithelial or myoepithelial cell to a stromal element and is called an epithelial-mesenchymal transition (EMT) resulting in heterogeneity. The present research was aimed to study the morphological characteristics of varied components and epithelial-mesenchymal transitions in PA using histopathological and immunohistochemical (IHC) analysis. Read More

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January 2019
2 Reads

[Clinical pathologic analysis on 3 724 cases of salivary gland tumors].

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Jan;54(1):10-16

Department of Pathology, Hospital of Stomatology, Jilin University, Changchun 130021, China.

To investigate the incidence and proportion of salivary gland tumors in order to provide new thinking for clinical diagnosis and treatment. Collected 3 724 cases salivary gland tumors diagnosed by Pathology Department of Hospital of Stomatology, Jilin University from January 1961 to December 2016. The pathological diagnosis referred to the fourth edition of head and neck-salivary gland tumor histopathological classification standard of WHO. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1002-0098.2019.01.003DOI Listing
January 2019
2 Reads

Lacrimal gland pleomorphic adenoma: a review of 52 cases, 15-year experience.

Acta Otolaryngol 2019 Jan 10:1-5. Epub 2019 Jan 10.

a Department of Otolaryngology - Orbital Surgery , Clinica Clarós , Barcelona , Spain.

Background: Lacrimal gland (LG) tumours are rare neoplasms. Pleomorphic adenoma (PA) is the most common histologic variant, representing ∼20% of all LG tumours. PA tends to recur leading to great morbidity. Read More

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http://dx.doi.org/10.1080/00016489.2018.1541362DOI Listing
January 2019
2 Reads

Classification of tumors by imaging diagnosis and preoperative fine-needle aspiration cytology in 120 patients with tumors in the parapharyngeal space.

Head Neck 2019 Jan 8. Epub 2019 Jan 8.

Otorhinolaryngology and Head and Neck Surgery, Kitasato University, Kanagawa, Japan.

Background: Tumors in the parapharyngeal space are rare, and preoperative diagnosis is difficult because of anatomical and histological complexity.

Methods: To evaluate the usefulness of preoperative diagnosis, we compared the classification of tumor localization in the prestyloid and retrostyloid compartments by imaging and preoperative cytological diagnosis by fine-needle aspiration cytology with the postoperative histopathological diagnosis in 120 patients with tumors in the parapharyngeal space.

Results: Tumors were located in the prestyloid and retrostyloid compartments in 68 and 52 patients, respectively. Read More

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http://doi.wiley.com/10.1002/hed.25552
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http://dx.doi.org/10.1002/hed.25552DOI Listing
January 2019
7 Reads

'Pleomorphic adenoma of the tongue: A common entity at the uncommon location'.

Ann Med Surg (Lond) 2019 Feb 23;38:34-36. Epub 2018 Dec 23.

Deptt. of Pathology, PGIMS Rohtak, Haryana, India.

The salivary gland tumors comprise of 3% of head and neck tumors. Pleomorphic adenoma, also known as mixed tumor, is the most common benign neoplasm of the major and minor salivary glands. The occurrence of pleomorphic adenoma of the tongue is very rare, and very few cases have been reported in the literature. Read More

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http://dx.doi.org/10.1016/j.amsu.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312764PMC
February 2019
2 Reads

Comparative Role of Matrixins in Diagnostics of Parotid Gland Tumors.

Authors:
E V Kochurova

Bull Exp Biol Med 2019 Jan 8;166(3):383-385. Epub 2019 Jan 8.

I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation, Moscow, Russia.

The benign and malignant neoplasms in parotid gland have similar clinical presentations despite different tumor growth rates. The study compared the clinical and morphological data as well as the results of ELISA for MMP-2, MMP-8, MMP-9, TIMP-1, and TIMP-2 in salivary fluid yielded during primary examination of the patients with pleomorphic adenoma and adenocarcinoma of parotid gland. The examined biomarkers detected in salivary fluid in patients with various cancer types differed significantly (p≤0. Read More

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http://dx.doi.org/10.1007/s10517-019-04355-wDOI Listing
January 2019
1 Read

Primary Pleomorphic Lipoma of the Parotid Gland with Prominent Myxoid Change: Report of a Rare Case Mimicking Carcinoma Ex Pleomorphic Adenoma on Fine Needle Aspiration Cytology.

Head Neck Pathol 2019 Jan 4. Epub 2019 Jan 4.

Department of Pathology, National University Hospital, Singapore, Singapore.

We present a case of a primary 2.5 cm pleomorphic lipoma of the right parotid gland with prominent myxoid change which on FNA displayed features that mimicked a carcinoma or sarcoma ex pleomorphic adenoma. The patient was a 79 year old man with no oncological history or tumor elsewhere. Read More

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http://link.springer.com/10.1007/s12105-018-00998-9
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http://dx.doi.org/10.1007/s12105-018-00998-9DOI Listing
January 2019
3 Reads

Salivary gland anlage tumor: molecular profiling sheds light on a morphologic question.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 Dec 3. Epub 2018 Dec 3.

Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.

Objective: Salivary gland anlage tumor (SGAT), previously described as a squamous proliferative lesion or "congenital pleomorphic adenoma," is a rare, benign entity that presents within the first months of life. It occurs almost exclusively in the nasopharynx or posterior nasal cavity and demonstrates a biphasic composition of epithelial and mesenchymal elements. Although the clinical and histologic features of SGAT are well described, its etiology remains poorly understood. Read More

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http://dx.doi.org/10.1016/j.oooo.2018.11.010DOI Listing
December 2018
1 Read

Fatty acid synthase and Ki-67 immunoexpression can be useful for the identification of malignant component in carcinoma ex-pleomorphic adenoma.

J Oral Pathol Med 2018 Dec 29. Epub 2018 Dec 29.

Department of Oral Diagnosis, Oral Pathology, Piracicaba Dental School, State University of Campinas (FOP-UNICAMP), Piracicaba, Brazil.

Background: Fatty acid synthase (FASN) is the key molecule for catalyzing fatty acid synthesis and have been associated with several malignant tumors.

Methods: We analyzed the expression of FASN and Ki-67, by immunohistochemistry on 29 carcinomas ex-pleomorphic adenoma (CXPAs) and 25 pleomorphic adenomas (PAs).

Results: Ki-67 proliferation index and FASN expression were significantly higher in patients with CXPA than patients with PA (P < 0. Read More

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http://doi.wiley.com/10.1111/jop.12820
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http://dx.doi.org/10.1111/jop.12820DOI Listing
December 2018
3 Reads

Pleomorphic adenoma of the epiglottis.

Acta Otorrinolaringol Esp 2018 Dec 24. Epub 2018 Dec 24.

Servicio de Otorrinolaringología, Complejo Hospitalario Universitario A Coruña, La Coruña, España.

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http://dx.doi.org/10.1016/j.otorri.2018.07.002DOI Listing
December 2018
1 Read

Association of Copy Number Variation at Intron 3 of With Navel Length in .

Front Genet 2018 7;9:627. Epub 2018 Dec 7.

Collaborating Centre on Animal Genomics and Bioinformatics, International Atomic Energy Agency, Araçatuba, Brazil.

Navel injuries caused by friction against the pasture can promote infection, reproductive problems and costly treatments in beef cattle raised in extensive systems. A haplotype-based genome-wide association study (GWAS) was performed for visual scores of navel length at yearling in Nellore cattle () using data from 2,016 animals and 503,088 single nucleotide polymorphism (SNP) markers. The strongest signal ( = 1. Read More

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http://dx.doi.org/10.3389/fgene.2018.00627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292862PMC
December 2018
2 Reads

A novel SNP of PLAG1 gene and its association with growth traits in Chinese cattle.

Gene 2019 Mar 21;689:166-171. Epub 2018 Dec 21.

College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China. Electronic address:

Genetic polymorphism has great influences on the improvement of cattle traits. The polymorphism of the same gene family will greatly change the growth traits of cattle, such as the pleomorphic adenoma gene (PLAG) family. Many studies have shown that the PLAG family proteins are the transcription regulators of nuclear protein, which mainly regulates the expression of many important genes in the body. Read More

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http://dx.doi.org/10.1016/j.gene.2018.12.018DOI Listing
March 2019
1 Read

Human epithelial growth factor receptor 2 in human salivary carcinoma ex pleomorphic adenoma: a potential therapeutic target.

Cancer Manag Res 2018 30;10:6571-6579. Epub 2018 Nov 30.

Department of Oral Pathology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Key Laboratory of Stomatology, Shanghai 200011, People's Republic of China,

Background: To inhibit human epithelial growth factor receptor 2 (HER2) in salivary carcinoma ex pleomorphic adenoma (CXPA) and investigate the effects on tumor cell proliferation, cell cycle, and apoptosis. To assess the possibility of blocking HER2 to improve the malignant biological behavior of CXPA.

Materials And Methods: HER2 expression and amplification were examined using an immunofluorescence assay and fluorescence in situ hybridization in 2 CXPA cell lines (SM-AP1 and SM-AP4 cells). Read More

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http://dx.doi.org/10.2147/CMAR.S182652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280888PMC
November 2018
2 Reads

[The surgical management of upper parapharyngeal regions].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1804-1809

Department of Otorhinolaryngology, the First Affiliated Hospital, Bengbu Medical College, Bengbu, 233004, China.

To find proper the surgical approval and evaluate clinical efficacy to treat the tumor of upper parapharyngeal space involving the base of skull and intracranial skull. The data of 9 cases from June 2013 and June 2018 were analyzed retrospectively including schwannoma in 6 cases, pleomorphic adenoma in 2 cases and hemangioma in 1 case. All cases received preoperative high resolution CT and MRI, some cases also did the DSA examination. Read More

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http://www.cnki.net/kcms/doi/10.13201/j.issn.1001-1781.2018.
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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.23.009DOI Listing
December 2018
10 Reads

Contemporary management of primary parapharyngeal space tumors.

Head Neck 2019 Feb 14;41(2):522-535. Epub 2018 Dec 14.

Coordinator of the International Head and Neck Scientific Group.

The parapharyngeal space is a complex anatomical area. Primary parapharyngeal tumors are rare tumors and 80% of them are benign. A variety of tumor types can develop in this location; most common are salivary gland neoplasm and neurogenic tumors. Read More

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http://dx.doi.org/10.1002/hed.25439DOI Listing
February 2019

Values of fine-needle aspiration cytology of parotid gland tumors: A review of 996 cases at a single institution.

Head Neck 2019 Feb 9;41(2):358-365. Epub 2018 Dec 9.

Department of Pathology, Osaka Medical College, Osaka, Japan.

Background: We evaluated the diagnostic accuracy of fine-needle aspiration cytology (FNAC) in a large series of benign and malignant parotid tumors.

Methods: The FNAC diagnosis of 821 benign and 175 malignant parotid tumors managed at our department between 1999 and 2017 was correlated with the final histology.

Results: FNAC made a correct histopathological diagnosis in 72% of the benign parotid tumors; however, FNAC provided a correct grade in only 34% of the malignant tumors. Read More

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http://dx.doi.org/10.1002/hed.25503DOI Listing
February 2019

Oncocytic cystadenoma and oncocytic cysts of the parotid gland occurring synchronously with a pleomorphic adenoma.

Br J Oral Maxillofac Surg 2019 Jan 3;57(1):95-96. Epub 2018 Dec 3.

Fiona Stanley Hospital.

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http://dx.doi.org/10.1016/j.bjoms.2018.10.283DOI Listing
January 2019
2 Reads

An Unusual Position of Retromandibular Vein in Relation to Facial Nerve: A Rare Case Report.

Case Rep Otolaryngol 2018 6;2018:3919762. Epub 2018 Nov 6.

Department of Head and Neck Oncology, Nepal Cancer Hospital, Lalitpur, Nepal.

Knowledge of different anatomical structures is very important in parotid surgery to preserve facial nerve. Retromandibular vein is one of the landmarks used to identify facial nerve. So, the relation of the vein with facial nerve is very important in parotid surgery. Read More

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http://dx.doi.org/10.1155/2018/3919762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247713PMC
November 2018
3 Reads

Pleomorphic adenoma of the mandibular salivary gland in a captive African pygmy hedgehog (Atelerix albiventris).

J Vet Med Sci 2019 Feb 7;81(2):177-181. Epub 2018 Dec 7.

Department of Veterinary Pathology and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.

A 3.9-year-old female African pygmy hedgehog (Atelerix albiventris) had a firm, tan-colored mass with an uneven surface arising from the mandibular salivary gland. A histopathologic examination revealed that the mass was composed of neoplastic proliferation of epithelial and spindle cells. Read More

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http://dx.doi.org/10.1292/jvms.18-0531DOI Listing
February 2019
1 Read

Proton therapy for treatment of intracranial benign tumors in adults: A systematic review.

Cancer Treat Rev 2019 Jan 1;72:56-64. Epub 2018 Dec 1.

Radiation Oncology Department, Centre François Baclesse, Caen, France; Archade, Advanced Resource Center for Hadrontherapy in Europe, Caen, France; Normandy University, Université de Caen Basse Normandie, Caen, France; Laboratoire de Physique Corpusculaire, Caen, France.

Introduction: The depth-dose distribution of a proton beam, materialized by the Bragg peak makes it an attractive radiation modality as it reduces exposure of healthy tissues to radiations, compared with photon therapy Prominent indications, based on a long-standing experience are: intraocular melanomas, low-grade skull-base and spinal canal malignancies. However, many others potential indications are under investigations such as the benign morbid conditions that are compatible with an extended life-expectancy: low grade meningiomas, paragangliomas, pituitary adenomas, neurinomas craniopharyngioma or recurrent pleomorphic adenomas.

Materials: Given the radiation-induced risk of secondary cancer and the potential neurocognitive and functional alteration with photonic radiotherapy, we systematically analyzed the existing clinical literature about the use of proton therapy as an irradiation modality for cervical or intracranial benign tumors. Read More

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http://dx.doi.org/10.1016/j.ctrv.2018.11.004DOI Listing
January 2019
2 Reads

Salivary gland tumors in a Brazilian population: A 20-year retrospective and multicentric study of 2292 cases.

J Craniomaxillofac Surg 2018 Dec 26;46(12):2227-2233. Epub 2018 Sep 26.

Postgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte-UFRN, Av. Senador Salgado Filho, 1787-Lagoa Nova, Natal, RN, 59056-000, Brazil. Electronic address:

Purpose: Neoplasms of the salivary glands comprise more than thirty subtypes of lesions with various clinical behaviors. The present study aimed to describe the incidence and main features of salivary gland tumors in Brazil.

Material And Methods: A retrospective descriptive cross-sectional study was performed (1997-2017). Read More

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http://dx.doi.org/10.1016/j.jcms.2018.09.028DOI Listing
December 2018
2 Reads

Intraparotid Facial Nerve Schwannoma in a Nine-Year-Old Patient: Diagnosis, Classification, and Surgical Approach Stages.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Pathology, The Ministry of Health Izmir Tepecik Training and Research Hospital, Izmir, Turkey.

Intraparotid facial nerve schwannoma (IFNS) is rarely observed in children compared with adults. Only a few cases have been reported in the literature. After radiological imaging and fine needle aspiration biopsy, an IFNS diagnosis may be skipped and confused with pleomorphic adenoma, which has a high prevalence among patients who have a mass in the parotid gland. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004980DOI Listing
November 2018
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A rare ectopic localization of pleomorphic adenoma.

J Stomatol Oral Maxillofac Surg 2018 Dec 1. Epub 2018 Dec 1.

Department of oral and ENT pathology, Pitié-Salpêtrière hospital, department of dermatology, Cochin-Port Royal hospital, Paris France.

Introduction: Pleomorphic adenoma (PA) is the most common benign salivary gland tumor, frequently affecting the major salivary glands but also the palatal or labial minor salivary glands. Pleomorphic adenomas affecting the retromolar trigone have seldom been reported with only few cases described in the literature.

Observation: We present the case of a young female patient who presented with this rare localization of pleomorphic adenoma and its subsequent management. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24687855183026
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http://dx.doi.org/10.1016/j.jormas.2018.11.016DOI Listing
December 2018
5 Reads

Diagnosis of an extremely rare pleomorphic adenoma of the breast with core needle biopsy: A case report.

Ann Med Surg (Lond) 2018 Dec 5;36:242-245. Epub 2018 Nov 5.

Takahashi Breast and Gastroenterology Clinic, Yamazaki Seiren Bldg. 2F, 6-2-22, Uehonmachi, Tennoji-Ku, 543-0001, Osaka, Japan.

Introduction: Pleomorphic adenoma (PA) rarely originates in the mammary gland. This tumor is a benign mixed tumor and is commonly found in the salivary glands, but rarely shows findings similar to those of breast cancer. The tumor is misdiagnosed in 30-50% of the patients, including overdiagnosis of malignancy preoperatively, leading to unnecessary surgery for breast cancer. Read More

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http://dx.doi.org/10.1016/j.amsu.2018.10.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258873PMC
December 2018
1 Read

Parotid Lymphoepithelial Cyst in a HIV-Negative Individual: A Case Report.

Iran J Med Sci 2018 Nov;43(6):668-670

Department of General Surgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.

Benign lymphoepithelial cysts of the parotid are common in retropositive patients, but extremely rare in HIV-negative individuals. We present a 28-year-old man who presented with a painless, gradually increasing swelling in the left parotid region and was clinically diagnosed to have a pleomorphic adenoma of the left parotid gland. Preoperative blood investigations revealed that the patient was seronegative. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230938PMC
November 2018
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A comparison of conventional and diffusion-weighted magnetic resonance imaging in the diagnosis of sialadenitis and pleomorphic adenoma.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 Oct 18. Epub 2018 Oct 18.

Department of Stomatology, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil.

Objectives: The aim of this study was to compare the efficacy of conventional magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) in correctly identifying the presence of disease in the major salivary glands and correctly distinguish sialadenitis from pleomorphic adenoma.

Study Design: Twenty-one patients diagnosed with unilateral sialadenitis or pleomorphic adenoma were selected. The nonaffected contralateral glands were also analyzed. Read More

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http://dx.doi.org/10.1016/j.oooo.2018.10.006DOI Listing
October 2018

Non-contrast computed tomography and magnetic resonance imaging features of mucoepidermoid carcinoma in the salivary glands.

Oral Radiol 2018 Jan 27;34(1):24-30. Epub 2017 Mar 27.

Department of Oral Radiology, Osaka Dental University, 1-5-17, Otemae, Chuo-ku, Osaka, 540-0008, Japan.

Background: Use of contrast-enhanced cross-sectional imaging is considered standard practice for investigating mucoepidermoid carcinoma (MEC) in the salivary glands. The purpose of this study was to present the common features of MEC on computed tomography (CT) and magnetic resonance imaging (MRI) without contrast enhancements, and to investigate the possibility of discriminating between MEC and pleomorphic adenoma based on the features observed on both modalities.

Methods: Twenty cases of biopsy-confirmed MEC originating in the salivary glands were reviewed and characterized by two oral and maxillofacial radiologists with regard to the following aspects: detectability, margin, border, encapsulation, content, contrast between lesion and masticator muscle, and bone changes. Read More

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http://dx.doi.org/10.1007/s11282-017-0281-0DOI Listing
January 2018
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Acantholytic Squamous Cell Carcinoma and Salivary Duct Carcinoma Ex-pleomorphic Adenoma of the Submandibular Gland: A Report of Two Extremely Rare Cases with an Immunohistochemical Analysis.

Head Neck Pathol 2018 Nov 27. Epub 2018 Nov 27.

Pathology Division, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.

Carcinoma ex pleomorphic adenoma (CXPA) is a malignant tumor of the salivary gland that arises from pleomorphic adenoma (PA). Squamous cell carcinoma (SCC) is extremely rare in the salivary glands. We report two cases of acantholytic SCC (ASCC) ex PA. Read More

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http://dx.doi.org/10.1007/s12105-018-0987-2DOI Listing
November 2018
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Diffusion-weighted magnetic resonance imaging in oral and maxillofacial lesions: preliminary study on diagnostic ability of apparent diffusion coefficient maps.

Oral Radiol 2018 Sep 4;34(3):224-228. Epub 2017 Sep 4.

Department of Radiology, The Nippon Dental University Niigata Hospital, 1-8 Hamaura-cho, Chuo-ku, Niigata, Niigata, 951-8580, Japan.

Objectives: The aim of this study was to investigate the usefulness of diffusion-weighted magnetic resonance imaging (DWI) in oral and maxillofacial lesions, especially the utility of apparent diffusion coefficient (ADC) maps for differential diagnosis of these lesions.

Methods: Fifty-seven patients who underwent magnetic resonance imaging for diagnosis of oral and maxillofacial lesions were included in this prospective study. DWI was performed on a 1. Read More

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http://dx.doi.org/10.1007/s11282-017-0303-yDOI Listing
September 2018
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Comparison of p63/p40 Expression With Myoepithelial Markers in Minor Salivary Gland Tumors.

Int J Surg Pathol 2018 Nov 27:1066896918813678. Epub 2018 Nov 27.

1 São Leopoldo Mandic Institute and Research Center, Campinas, São Paulo, Brazil.

The present study aimed to compare the expression of p63/p40 with smooth muscle actin (SMA) and vimentin (VIM) by myoepithelial cells in minor salivary gland tumors. Fifty-two formalin-fixed paraffin-embedded samples of minor salivary gland tumors derived from intercalated duct (pleomorphic adenoma [PA], adenoid cystic carcinoma [ACC], epithelial-myoepithelial carcinoma [EMC], polymorphous adenocarcinoma [PAC], and secretory carcinoma [SC]) and 3 samples of minor salivary gland tumors derived from excretory duct (mucoepidermoid carcinoma [MEC]) were evaluated by means of immunohistochemistry. The data were analyzed qualitatively. Read More

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http://dx.doi.org/10.1177/1066896918813678DOI Listing
November 2018
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Epidemiology of salivary gland tumours in an Eastern Caribbean nation: A retrospective study.

Ann Med Surg (Lond) 2018 Dec 8;36:148-151. Epub 2018 Nov 8.

Department of Clinical Surgical Science, University of the West Indies, St. Augustine, Trinidad and Tobago.

Objective: The epidemiology of the salivary glands tumour is not well documented in the Caribbean countries. Therefore, the aim of this study is to determine the local trend of salivary gland tumours with a review of current diagnostic techniques.

Design & Methods: Retrospective data was collected from the electronic database at the Pathology department of the San Fernando Teaching Hospital between the periods January 2005 to June 2015. Read More

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http://dx.doi.org/10.1016/j.amsu.2018.10.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240702PMC
December 2018
3 Reads