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Indian J Tuberc 2022 Jul 15;69(3):282-304. Epub 2021 Jul 15.

Division of Bioinformatics, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, District Dhule, Maharashtra, 425 405, India. Electronic address:

Tuberculosis is considered as a leading health issue globally. Even though, the todays first line anti-mycobacterial treatments used in the hospital have low deaths, multidrug-resistance forms of the ailment have now spread globally and become a major issue. The wide-ranging biodiversity of medicinal plants, ocean animals have gained considerable attention for drug discovery in previous spans, and the emergence of TB drug resistance has inspired interest in judging natural products (NPs) to cure this disease. Read More

J Genet Genomics 2022 Jun 24. Epub 2022 Jun 24.

State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, The Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing 100101, P. R. China; CAS Center for Excellence in Biotic Interactions, University of Chinese Academy of Sciences, Beijing 100049, P. R. China; Hainan Yazhou Bay Seed Laboratory, Sanya 572025, P. R. China. Electronic address:

Pseudomonas syringae pv. actinidiae (Psa) causes bacterial canker, a devastating disease threatening the Actinidia fruit industry. In a search for non-host resistance genes against Psa, we found that the nucleotide-binding leucine-rich repeat receptor (NLR) protein ZAR1 from both Arabidopsis and Nicotiana benthamiana (Nb) recognizes HopZ5 and triggers cell death. Read More

Andrologia 2022 Jun 27:e14511. Epub 2022 Jun 27.

Division of Endocrinology, Central Drug Research Institute, Lucknow, Uttar Pradesh, India.

Genistein, an isoflavonoid, is found in a plethora of plant-based foods, and has been approved for use in various therapies. A couple of studies in adult men observed a negative correlation between genistein exposure and reproductive parameters. To assess the effects of genistein exposure on reproduction and fertility the in males and females, we performed quantitative meta-analyses by pooling data from published studies on animals that assessed various reproductive parameters. Read More

Gene 2022 Jun 24:146692. Epub 2022 Jun 24.

Laboratory of Modern Biotechnology, School of Forestry and Landscape Architecture, Anhui Agricultural University, Hefei, 230036, China. Electronic address:

SAUR (small auxin-up RNA) is an early auxin-responsive gene. In this study, a novel SAUR gene PtSAUR8 was cloned from poplar (Populus trichocarpa), and subcellular location analysis showed that it is targeted to the nuclear membrane. In addition, PtSAUR8 overexpression in Arabidopsis improved the plant resistance to drought stress. Read More

J Ethnopharmacol 2022 Jun 24:115504. Epub 2022 Jun 24.

Departamento de Bioquímica, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil. Electronic address:

Ethnopharmacological Relevance: Moringa oleifera Lam. leaves infusion and powder are widely used by population due the nutritional and medicinal potentials, however data regarding safety of use are still inconclusive, leading to prohibition of this plant in some countries.

Aim Of The Study: The present work investigated the nutritional and phytochemical composition, acute and 28-day repeated dose toxicity, and genotoxicity of M. Read More

J Ethnopharmacol 2022 Jun 24:115509. Epub 2022 Jun 24.

Department of Natural Drugs, Czech Republic. Electronic address:

Ethnopharmacological Relevance: Paulownia tomentosa Steud., a traditional Chinese medicinal plant, was used for many centuries in Chinese herbal medicine as a component of remedies for many illnesses, including inflammatory diseases. It is a rich source of phenolic compounds, mainly geranylated flavonoids, which are currently studied for their promising biological activities. Read More

Bioresour Technol 2022 Jun 24:127528. Epub 2022 Jun 24.

National Engineering Laboratory for Advanced Municipal Wastewater Treatment and Reuse Technology, Engineering Research Center of Beijing, Beijing University of Technology, Beijing 100124, PR China.

In order to promote practical engineering application of anaerobic ammonium oxidation(anammox) process, reduction of primary sludge(PS) in wastewater treatment plants(WWTPs) and removal of nitrate contaminant, a single-stage simultaneous alkaline fermentation coupled with partial denitrification(SAFPD) system was established successfully in this study. Nitrite production was rapidly achieved from nitrate wastewater with PS as inoculated sludge and fermentable substrate under anaerobic and anoxic operating conditions. During the stable operation period, the primary sludge reduction(PSR) and productivity of organic matters were 27. Read More

Genomics 2022 Jun 24:110420. Epub 2022 Jun 24.

Sugarcane Research Institute of Guangxi Academy of Agricultural Sciences, East Daxue Road 172, Nanning 530007, Guangxi, China; Guangxi Key Laboratory of Sugarcane Genetic Improvement, East Daxue Road 172, Nanning, 530007, Guangxi, China; Key Laboratory of Sugarcane Biotechnology and Genetic Improvement (Guangxi), Ministry of Agriculture, East Daxue Road 172, Nanning 530007, Guangxi, China. Electronic address:

microRNA (miRNA) is a group of small non-coding RNA that plays important role in post-transcription of gene expression. With the studies about miRNA increase in sugarcane, the researchers lack an exhaustive resource to achieve the data. To fill this gap, we developed MicroSugar, a database that supported mRNA and miRNA annotation for sugarcane (http://suc. Read More

Sci Total Environ 2022 Jun 24:156857. Epub 2022 Jun 24.

French Agency for Food, Environmental and Occupational Health & Safety (ANSES), Maisons-Alfort Laboratory for Animal Health, France; ANSES, Sophia Antipolis laboratory, Unit of Honey bee Pathology, European Reference Laboratory for Honeybee health, F-06902 Sophia Antipolis, France.

Multiple stressors, threaten bee health, a major one being pesticides. Bees are simultaneously exposed to multiple pesticides that can cause both lethal and sublethal effects. Risk assessment and most research on bee health, however, focus on lethal individual effects. Read More

Int J Biol Macromol 2022 Jun 24. Epub 2022 Jun 24.

TERI-Deakin Nanobiotechnology Centre, The Energy and Resources Institute, Gurugram, Haryana 122001, India. Electronic address:

Productivity enhancement approaches, such as elicitation can overcome the limitations of low metabolite(s) yield in in vitro plant cell culture platforms. Application of biotic/abiotic elicitors triggers molecular responses that lead to a concomitant enhancement in the production of metabolites. Nanoparticles have been tested as alternatives to commonly studied biotic/abiotic elicitors. Read More

Plant Sci 2022 Jun 24:111361. Epub 2022 Jun 24.

Department of Plant Biology, Rutgers, the State University of New Jersey, New Brunswick, New Jersey, USA. Electronic address:

Fusarium head blight (FHB) caused by Fusarium graminearum (Fg) severely affects cereal crops, especially wheat and barley. FHB results in significant yield loss, reduces grain quality and contaminates grains with mycotoxin. The development of FHB-resistant cereal cultivars can be expedited through CRISPR gene editing. Read More

Plant Sci 2022 Jun 24:111364. Epub 2022 Jun 24.

Department of Crop and Soil Sciences, North Carolina State University, Raleigh, North Carolina 27695. Electronic address:

Arbuscular mycorrhizal (AM) fungi considerably improve plant nutrient acquisition, particularly phosphorus and nitrogen. Despite the physiological importance of potassium (K) in plants, there is increasing interest in the mycorrhizal contribution to plant K nutrition. Yet, methods to track K transport are often costly and limiting evaluation opportunities. Read More

Chemosphere 2022 Jun 24:135492. Epub 2022 Jun 24.

Center for Ecological-Noosphere Studies of NAS RA, Abovyan 68, 0025, Yerevan, Armenia.

Soil geochemical data is compositional. Hence the studies targeting the potential of accumulation of toxic elements (TE) in plants have to consider the compositional nature of soil chemical environment. In this study, the combined application of compositional data analysis and geospatial mapping was used to investigate Pb geochemical associations in agricultural soils, revealing the link between these associations and Pb contents in plants, as well as identifying source-specific transfer of Pb from soil to plants. Read More

Biochem Pharmacol 2022 Jun 24:115120. Epub 2022 Jun 24.

Department of Respiratory and Critical Care Medicine, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai 201399, PR. China. Electronic address:

Acute lung injury (ALI) is a severe clinical disease marked by uncontrolled inflammation response which lacks effective medicines. Accumulative evidence has indicated that macrophages are therapeutic targets for treating ALI because of its critical role in the inflammatory response.Palmatine (PAL), an isoquinoline alkaloid extracted from natural plants, exhibits effective anti-inflammatory, anti-tumor, and anti-oxidation activities. Read More

J Plant Physiol 2022 Jun 11;275:153753. Epub 2022 Jun 11.

Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China. Electronic address:

Duckweed is a kind of aquatic plant with the characteristics of high nutritional value and medicinal benefits. However, most researches focused on the natural germplasms. The underlying metabolic pathway remains to be systematically elaborated in duckweed. Read More

Waste Manag 2022 Jun 24;149:291-301. Epub 2022 Jun 24.

Regional Municipal Waste Treatment Plant in Elbląg, Poland.

Although the requirements for overall recycling rates can only be met when organic recycling is not overlooked, information is scarce regarding adaption to biowaste composting of existing mechanical-biological treatment (MBT) plants originally designed for stabilization of organic municipal solid waste (OFMSW). Thus, this study aimed to assess the suitability of the operational conditions in the biological part of a full-scale MBT plant now used for stabilization of OFMSW (working line: closed-module-covered-pile-open-pile) with a view to producing compost from biowaste. Temperatures above 75 °C were maintained in the closed module and reached again in the covered pile, indicating that intensive organic-matter mineralization occurred in both stages. Read More

Waste Manag 2022 Jun 24;149:259-290. Epub 2022 Jun 24.

Department of Anthropogenic Material Cycles, RWTH Aachen University, Germany.

Digital technologies hold enormous potential for improving the performance of future-generation sorting and processing plants; however, this potential remains largely untapped. Improved sensor-based material flow characterization (SBMC) methods could enable new sensor applications such as adaptive plant control, improved sensor-based sorting (SBS), and more far-reaching data utilizations along the value chain. This review aims to expedite research on SBMC by (i) providing a comprehensive overview of existing SBMC publications, (ii) summarizing existing SBMC methods, and (iii) identifying future research potentials in SBMC. Read More

J Environ Manage 2022 Jun 24;318:115511. Epub 2022 Jun 24.

Institute of Aquaculture, University of Stirling, Stirling, Scotland, UK. Electronic address:

Stable isotope ratios, carbon (δC) and nitrogen (δN), and fatty acids validated the trophic connection between farmed fish in a commercial nearshore fish farm and sea cucumbers in the Mediterranean Sea. This dual tracer approach evaluated organic matter transfer in integrated multi-trophic aquaculture (IMTA) and the ability of sea cucumbers to incorporate fish farm waste (fish faeces and uneaten artificial fish feed) into their tissue. Between October 2018 and September 2019, Holothuria (Roweothuria) poli Delle Chiaje, 1824, co-cultured at IMTA sites directly below one of the commercial fish cage , at 10 m and 25 m from the selected fish cage, and at two reference sites over 800 m from the fish farm. Read More

J Environ Manage 2022 Jun 24;318:115522. Epub 2022 Jun 24.

Department of Biology, Institute of Biosciences, São Paulo State University (Unesp), Av. 24-A, 1515, 13506-900, Rio Claro, SP, Brazil. Electronic address:

Wastewater reuse is an important strategy for water resource management. For this reason, the disinfection process must be appropriated, eliminating pathogenic microorganisms. Ozonation (O) and UV/HO treatments can be used for effluent disinfection, but few studies just address the Escherichia coli quantification. Read More

Syst Appl Microbiol 2022 Jun 18;45(4):126343. Epub 2022 Jun 18.

Laboratory of Legumes and Sustainable Agroecosystems, Centre of Biotechnology of Borj-Cédria, BP 901 Hammam-lif 2050, Tunisia. Electronic address:

Acacia saligna is an invasive alien species that has the ability to establish symbiotic relationships with rhizobia. In the present study, genotypic and symbiotic diversity of native rhizobia associated with A. saligna in Tunisia were studied. Read More

Water Res 2022 Jun 19;221:118781. Epub 2022 Jun 19.

Bren School of Environmental Science & Management, University of California, Santa Barbara, USA. Electronic address:

Fecal sources to recreational surf zone waters should be identified to protect public health. While watershed origins of human and other fecal sources are often discoverable by quantitative polymerase chain reaction (qPCR) of fecal markers using spatially stratified samples, similarly assessing wastewater treatment plant (WWTP) outfall and other offshore contributions to surf zones is challenged by individual marker fate and transport. Here, bacterial communities were assessed for relatedness between all hypothesized fecal sources and surf zone waters for two urban California recreational beaches, by sequencing genes encoding 16S rRNA and analyzing data using SourceTracker and FEAST. Read More

Water Res 2022 Jun 19;221:118783. Epub 2022 Jun 19.

The Key Laboratory of Water and Sediment Sciences, Ministry of Education; College of Environmental Sciences and Engineering, Peking University, Beijing 100871, PR China. Electronic address:

The release of microplastics (MPs) especially those with sizes less than 10 μm from effluent of wastewater treatment plants (WWTPs) is one of the major sources of plastics into aquatic environment. To reduce the discharge of MPs into environment, it is essential to further enhance their removal efficiencies in WWTPs. In present study, to boost the removal performance of MPs in sand filtration systems (units that commonly employed in WWTPs to remove colloidal pollutants), six types of biochar fabricated from three raw biomass materials (i. Read More

Water Res 2022 Jun 19;221:118780. Epub 2022 Jun 19.

Centre for Technology in Water and Wastewater, School of Civil and Environmental Engineering, University of Technology Sydney, Sydney, NSW 2007, Australia.

Microplastics (MPs) have been frequently detected in effluent wastewater and sludge in wastewater treatment plants (WWTPs), the discharge and agricultural application of which represent a primary source of environmental MPs contamination. As important as quantitative removal is, changes of physicochemical characteristics of MPs (e.g. Read More

Food Chem 2022 Jun 21;394:133541. Epub 2022 Jun 21.

Department of Plant Sciences, North Dakota State University, Fargo, ND 58108, USA. Electronic address:

In this study, HS-SPME/GC-MS based untargeted and targeted flavoromics combing with olfactometry were employed to uncover aroma boundary compositions of five types of commercial barley malts with a wide range of Lovibond (L), including kilned base malts (1.8 L and 3.5 L) and roasted caramel malts (10 L, 60 L, and 120 L). Read More

Anal Chem 2022 Jun 27. Epub 2022 Jun 27.

College of Chemistry, Zhengzhou University, Henan 450001, China.

Here, we develop a sensitive method for glucose-containing disaccharide analysis by 1-(4-carboxyphenyl)-3-methyl-5-pyrazolone (CPMP) derivatization using mass spectrometry. The intense anion of [M - H] (/ 759) was observed for CPMP-labeled disaccharides in a negative mode. After derivatization, its sensitivity was significantly increased with the limits of detection (LODs) and limits of quantification (LOQ) ranging from 3. Read More

Proc Natl Acad Sci U S A 2022 Jul 27;119(27):e2206075119. Epub 2022 Jun 27.

State Key Laboratory of Protein and Plant Gene Research, School of Advanced Agricultural Sciences and School of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.

The master transcriptional repressor DREAM (dimerization partner, RB-like, E2F and multivulval class B) complex regulates the cell cycle in eukaryotes, but much remains unknown about how it transmits repressive signals on chromatin to the primary transcriptional machinery (e.g., RNA polymerase II [Pol II]). Read More

Proc Natl Acad Sci U S A 2022 Jul 27;119(27):e2001290119. Epub 2022 Jun 27.

BIAM, UMR 7265, Aix Marseille Univ, CEA, CNRS, Marseille, F-13009 France.

The organization of the genome into transcriptionally active and inactive chromatin domains requires well-delineated chromatin boundaries and insulator functions in order to maintain the identity of adjacent genomic loci with antagonistic chromatin marks and functionality. In plants that lack known chromatin insulators, the mechanisms that prevent heterochromatin spreading into euchromatin remain to be identified. Here, we show that DNA Topoisomerase VI participates in a chromatin boundary function that safeguards the expression of genes in euchromatin islands within silenced heterochromatin regions. Read More

Environ Sci Technol 2022 Jun 27. Epub 2022 Jun 27.

Plant Physiology, Bayreuth Center for Ecology and Environmental Research (BayCEER), University of Bayreuth, D-95440 Bayreuth, Germany.

Arsenic is one of the most relevant environmental pollutants and human health threats. Several arsenic species occur in soil pore waters. Recently, it was discovered that these include inorganic and organic thioarsenates. Read More

CBE Life Sci Educ 2022 Sep;21(3):ar42

Department of Genetics, University of Georgia, Athens, GA 30602.

Most science, technology, engineering, and mathematics (STEM) departments inadequately evaluate teaching, which means they are not equipped to recognize or reward effective teaching. As part of a project at one institution, we observed that departmental chairs needed help recognizing the decisions they would need to make to improve teaching evaluation practices. To meet this need, we developed the Guides to Advance Teaching Evaluation (GATEs), using an iterative development process. Read More

J Microsc 2022 Jun 27. Epub 2022 Jun 27.

Laboratory of Biochemistry, Wageningen University.

As many multicellular organisms, land plants start their life as a single cell, which forms an embryo. Embryo morphology is relatively simple, yet comprises basic tissues and organs, as well as stem cells that sustain post-embryonic development. Being condensed in both time and space, early plant embryogenesis offers an excellent window to study general principles of plant development. Read More