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    5 results match your criteria Plant Poisoning Alkaloids - Quinolizidine & Isoquinoline

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    Lupines, poison-hemlock and Nicotiana spp: toxicity and teratogenicity in livestock.
    J Nat Toxins 1999 Feb;8(1):117-34
    Poisonous Plant Research Laboratory, USDA Agricultural Research Service, Logan, UT 84341, USA.
    Many species of lupines contain quinolizidine or piperidine alkaloids known to be toxic or teratogenic to livestock. Poison-hemlock (Conium maculatum) and Nicotiana spp. including N. Read More

    Teratological research at the USDA-ARS poisonous plant research laboratory.
    J Nat Toxins 1999 Feb;8(1):63-80
    USDA-ARS Poisonous Plant Research Laboratory, Logan, UT 84341, USA.
    Research on teratogenic plants started at the USDA-Agricultural Research Service-Poisonous Plant Research Laboratory in the mid 1950s when Dr. Wayne Binns, Director of the laboratory, was asked to investigate the cause of a cyclopian facial/skeletal birth defect in lambs. Dr. Read More

    Quinolizidine and piperidine alkaloid teratogens from poisonous plants and their mechanism of action in animals.
    Vet Clin North Am Food Anim Pract 1993 Mar;9(1):33-40
    United States Department of Agriculture, Poisonous Plant Research Laboratory, Logan, Utah.
    Quinolizidine and piperidine alkaloid teratogens from Lupinus, Conium, and Nicotiana genera have been identified as causes of birth defects in livestock induced by poisonous plants. Many defects now known to be related to poisonous plant ingestion were once thought to have a genetic origin. This supposition delayed diagnosis, reporting, and understanding of such birth defects, because breeders and producers feared the news would make it difficult to sell breeding stock. Read More

    Natural plant toxicants in milk: a review.
    J Anim Sci 1990 Mar;68(3):892-904
    U.S. Department of Agriculture, Logan, UT 84321.
    Elimination of plant toxicants via milk by lactating animals is considered a minor route of excretion; however, it may be important when the health of the neonate or food safety in humans is considered. Among plant toxicants excreted in milk is tremetol or tremetone, the toxin in white snakeroot (Eupatorium rugosum) and rayless goldenrod (Haplopappus heterophyllus). These plants have been responsible for intoxication of cows and their suckling calves and for many human poisonings. Read More

    Congenital skeletal malformations and cleft palate induced in goats by ingestion of Lupinus, Conium and Nicotiana species.
    Toxicon 1990 ;28(12):1377-85
    USDA/ARS/Poisonous Plant Research Laboratory, Logan, UT 84321.
    Three piperidine alkaloid containing plants, Conium maculatum (poison-hemlock), Nicotiana glauca (tree tobacco) and Lupinus formosus (lunara lupine), induced multiple congenital contractures (MCC) and palatoschisis in goat kids when their dams were gavaged with the plant during gestation days 30-60. The skeletal abnormalities included fixed extension or flexure of the carpal, tarsal, and fetlock joints, scoliosis, lordosis, torticollis and rib cage abnormalities. Clinical signs of toxicity included those reported in sheep, cattle and pigs--ataxia, incoordination, muscular weakness, prostration and death. Read More

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