7 results match your criteria Plant Poisoning Alkaloids - Quinolizidine & Isoquinoline

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An Evaluation of Hair, Oral Fluid, Earwax, and Nasal Mucus as Noninvasive Specimens to Determine Livestock Exposure to Teratogenic Lupine spp.

J Agric Food Chem 2018 Dec 7. Epub 2018 Dec 7.

The livestock industry in the western United States loses an estimated $500 million annually from livestock production losses due to poisonous plants. Poisoning of livestock by plants often goes undiagnosed because there is a lack of appropriate or available specimens for analysis. Lupinus species represent an important toxic plant in western North America that can be toxic and/or teratogenic to livestock species due to the quinolizidine alkaloids. Read More

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http://dx.doi.org/10.1021/acs.jafc.8b05673DOI Listing
December 2018
1 Read

Poisoning after Ingestion of Spartium junceum Seeds: Dose-Dependent Effects in Three Boys.

J Emerg Med 2017 Sep;53(3):e41-e44

Toxicology Laboratory, Universitat Autònoma de Barcelona, Spain.

Background: Spanish broom (Spartium junceum L.) is an ornamental, medicinal, and potentially poisonous plant.

Case Report: Three children, aged 5-6 years, were accidentally poisoned from ingesting a variable number of seeds of Spanish broom. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07364679173037
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http://dx.doi.org/10.1016/j.jemermed.2017.04.033DOI Listing
September 2017
5 Reads

Lupines, poison-hemlock and Nicotiana spp: toxicity and teratogenicity in livestock.

J Nat Toxins 1999 Feb;8(1):117-34

Poisonous Plant Research Laboratory, USDA Agricultural Research Service, Logan, UT 84341, USA.

Many species of lupines contain quinolizidine or piperidine alkaloids known to be toxic or teratogenic to livestock. Poison-hemlock (Conium maculatum) and Nicotiana spp. including N. Read More

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February 1999
27 Reads

Teratological research at the USDA-ARS poisonous plant research laboratory.

Authors:
L F James

J Nat Toxins 1999 Feb;8(1):63-80

USDA-ARS Poisonous Plant Research Laboratory, Logan, UT 84341, USA.

Research on teratogenic plants started at the USDA-Agricultural Research Service-Poisonous Plant Research Laboratory in the mid 1950s when Dr. Wayne Binns, Director of the laboratory, was asked to investigate the cause of a cyclopian facial/skeletal birth defect in lambs. Dr. Read More

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February 1999
3 Reads

Quinolizidine and piperidine alkaloid teratogens from poisonous plants and their mechanism of action in animals.

Vet Clin North Am Food Anim Pract 1993 Mar;9(1):33-40

United States Department of Agriculture, Poisonous Plant Research Laboratory, Logan, Utah.

Quinolizidine and piperidine alkaloid teratogens from Lupinus, Conium, and Nicotiana genera have been identified as causes of birth defects in livestock induced by poisonous plants. Many defects now known to be related to poisonous plant ingestion were once thought to have a genetic origin. This supposition delayed diagnosis, reporting, and understanding of such birth defects, because breeders and producers feared the news would make it difficult to sell breeding stock. Read More

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March 1993
3 Reads

Natural plant toxicants in milk: a review.

J Anim Sci 1990 Mar;68(3):892-904

U.S. Department of Agriculture, Logan, UT 84321.

Elimination of plant toxicants via milk by lactating animals is considered a minor route of excretion; however, it may be important when the health of the neonate or food safety in humans is considered. Among plant toxicants excreted in milk is tremetol or tremetone, the toxin in white snakeroot (Eupatorium rugosum) and rayless goldenrod (Haplopappus heterophyllus). These plants have been responsible for intoxication of cows and their suckling calves and for many human poisonings. Read More

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March 1990
3 Reads

Congenital skeletal malformations and cleft palate induced in goats by ingestion of Lupinus, Conium and Nicotiana species.

Toxicon 1990 ;28(12):1377-85

USDA/ARS/Poisonous Plant Research Laboratory, Logan, UT 84321.

Three piperidine alkaloid containing plants, Conium maculatum (poison-hemlock), Nicotiana glauca (tree tobacco) and Lupinus formosus (lunara lupine), induced multiple congenital contractures (MCC) and palatoschisis in goat kids when their dams were gavaged with the plant during gestation days 30-60. The skeletal abnormalities included fixed extension or flexure of the carpal, tarsal, and fetlock joints, scoliosis, lordosis, torticollis and rib cage abnormalities. Clinical signs of toxicity included those reported in sheep, cattle and pigs--ataxia, incoordination, muscular weakness, prostration and death. Read More

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May 1991
14 Reads
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