Search Our Scientific Publications & Authors

Planta Med 2019 Apr 24. Epub 2019 Apr 24.

Department of Pharmacology, Faculty of Pharmacy, University of Seville, Seville, Spain.

L. (Fagaceae) is one of the most commonly used plants in folk medicine in the Mediterranean region to treat gastrointestinal disorders. The aim of the present study was to evaluate the effects of a polyphenol extract from mature leaves of on acute 2,4,6-trinitrobenzene sulfonic acid-induced colitis in rats. Read More

J Ethnopharmacol 2019 Apr 21:111902. Epub 2019 Apr 21.

TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, 410208, PR China. Electronic address:

Ethnopharmacological Relevance: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by failure of spontaneous resolution of inflammation. The stem of Kadsura heteroclite (KHS) is a well-known anti-arthritic Tujia ethnomedicinal plant, which named Xuetong in folk, has long been used for the prevention and treatment of rheumatic and arthritic diseases.

Aim Of The Study: The analgesic and anti-inflammatory effects and the potential mechanisms behind such effects of KHS would be investigated by using different animal models. Read More

Cell Rep 2019 Apr;27(4):1018-1026.e4

The Roslin Institute, University of Edinburgh, Easter Bush Campus, Midlothian, Edinburgh EH25 9RG, UK; Euan MacDonald Centre, Chancellor's Building, University of Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK; Centre for Dementia Prevention, University of Edinburgh, 9A Bioquarter, 9 Little France Road, Edinburgh EH16 4UX, UK. Electronic address:

Normal mammalian brain aging is characterized by the selective loss of discrete populations of dendritic spines and synapses, particularly affecting neuroanatomical regions such as the hippocampus. Although previous investigations have quantified this morphologically, the molecular pathways orchestrating preferential synaptic vulnerability remain to be elucidated. Using quantitative proteomics and healthy rhesus macaque and human patient brain regional tissues, we have comprehensively profiled the temporal expression of the synaptic proteome throughout the adult lifespan in differentially vulnerable brain regions. Read More

Ecology 2019 Apr 24:e02682. Epub 2019 Apr 24.

Department of Entomology, University of California, Davis, California, 95616, USA.

Biological invasions are increasingly being considered important spatial processes that drive global changes, threatening biodiversity, regional economies, and ecosystem functions. A unifying conceptual model of the invasion dynamics could serve as a useful tool for comparison and classification of invasion processes involving different species across large geographic ranges. By dividing these geographic ranges that are subject to invasions into discrete spatial units, we here conceptualize the invasion process as the transition from pristine to invaded spatial units. Read More

Plant Cell Environ 2019 Apr 24. Epub 2019 Apr 24.

Plant Physiology Lab, Bioscience Faculty, Universidad Autónoma de Barcelona.

High soil carbonate limits crop performance especially in semi-arid or arid climates. To understand how plants adapt to such soils, we explored natural variation in tolerance to soil carbonate in small local populations (demes) of Arabidopsis thaliana growing on soils differing in carbonate content. Reciprocal field-based transplants on soils with elevated carbonate (+C) and without carbonate (-C) over several years revealed that demes native to (+C) soils showed higher fitness than those native to (-C) soils when both were grown together on carbonate-rich soil. Read More

J Mass Spectrom 2019 Apr 24. Epub 2019 Apr 24.

Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, 99352.

The spatial configuration and morphology of roots are commonly monitored for a better understanding of plant health and development. However, this approach provides minimal details about the biochemistry regulating the observable traits. Therefore, the ability to metabolically map the entire root structure would be of major value. Read More

PLoS Pathog 2019 Apr 24;15(4):e1007708. Epub 2019 Apr 24.

Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel.

Infection by large dsDNA viruses can lead to a profound alteration of host transcriptome and metabolome in order to provide essential building blocks to support the high metabolic demand for viral assembly and egress. Host response to viral infection can typically lead to diverse phenotypic outcome that include shift in host life cycle and activation of anti-viral defense response. Nevertheless, there is a major bottleneck to discern between viral hijacking strategies and host defense responses when averaging bulk population response. Read More

PLoS One 2019 24;14(4):e0215645. Epub 2019 Apr 24.

Department of Plant Ecology & Environmental Conservation, Institute of Botany, Biological and Chemical Research Centre, University of Warsaw, Warsaw, Poland.

In peatland restoration we often lack an information whether re-established ecosystems are functionally similar to non-degraded ones. We re-analysed the long-term outcomes of restoration on vegetation and plant functional traits in 38 European fens restored by rewetting (18 sites) and topsoil removal (20 sites). We used traits related to nutrient acquisition strategies, competitiveness, seed traits, and used single- and multi-trait metrics. Read More

PLoS One 2019 24;14(4):e0215988. Epub 2019 Apr 24.

Department of Biology, York University, Toronto, Ontario, Canada.

The mechanisms supporting positive ecological interactions are important. Foundation species can structure desert biodiversity by facilitating seedbanks of annual plants, but the direct and indirect mechanisms of shrub effects on seedbank have not been experimentally decoupled. We conducted the first test of shrubs increasing seedbank densities through direct effects on the seedbank (i. Read More

PLoS One 2019 24;14(4):e0214315. Epub 2019 Apr 24.

University of Maribor, Faculty of Mechanical Engineering, Laboratory for Structure Evaluation, Maribor, Slovenia.

In the process of applying a plant protection product mixed with water (spray mixture) at the prescribed concentration with conventional sprayers for chemical protection of tree canopies in an orchard, standard models are used to express the dose rate of the plant protection product. Characteristic properties of the tree canopy in an orchard are not taken into consideration. Such models result in fixed quantities of spray mixture being sprayed through individual nozzles into a tree canopy. Read More

PLoS One 2019 24;14(4):e0214909. Epub 2019 Apr 24.

Department of Ecology, Evolution, and Natural Resources, Rutgers University, New Brunswick,New Jersey, United States of America.

Background: Intraspecific variation in foraging niche can drive food web dynamics and ecosystem processes. In particular, male and female animals can exhibit different, often cascading, impacts on their interaction partners. Despite this, studies of plant-pollinator interaction networks have focused on the partitioning of the floral community between pollinator species, with little attention paid to intraspecific variation in plant preference between male and female bees. Read More

PLoS One 2019 24;14(4):e0214955. Epub 2019 Apr 24.

Instituto Universitario de Biorgánica Antonio González, Universidad de La Laguna, La Laguna, Santa Cruz de Tenerife, Spain.

Middle Paleolithic lithic and faunal assemblages throughout Eurasia reflect short-term Neanderthal occupations, which suggest high group mobility. However, the timing of these short-term occupations, a key factor to assess group mobility and territorial range, remains unresolved. Anthropogenic combustion structures are prominent in the Middle Paleolithic record and conceal information on the timing and intensity and natural setting of their associated human occupations. Read More

PLoS One 2019 24;14(4):e0213572. Epub 2019 Apr 24.

Instituto de Ciencias de la Tierra, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile.

The present study describes the discovery of a singular sedimentary structure corresponding to an ichnite that was excavated at the paleo-archaeological site Pilauco (Osorno, Chile). The trace fossil is associated with megafauna bones, plant material and unifacial lithic tools. Here we present a detailed analysis of the Pilauco ichnite and associated sedimentary structures, as well as new radiocarbon data. Read More

PLoS Biol 2019 Apr 24;17(4):e3000214. Epub 2019 Apr 24.

Max Planck Institute for Developmental Biology, Tübingen, Germany.

Heterosis describes the phenotypic superiority of hybrids over their parents in traits related to agronomic performance and fitness. Understanding and predicting nonadditive inheritance such as heterosis is crucial for evolutionary biology as well as for plant and animal breeding. However, the physiological bases of heterosis remain debated. Read More

PLoS Genet 2019 Apr 24;15(4):e1008116. Epub 2019 Apr 24.

College of Plant Protection, Nanjing Agricultural University, Nanjing, China.

Pythium guiyangense, an oomycete from a genus of mostly plant pathogens, is an effective biological control agent that has wide potential to manage diverse mosquitoes. However, its mosquito-killing mechanisms are almost unknown. In this study, we observed that P. Read More

PLoS Biol 2019 Apr 24;17(4):e3000215. Epub 2019 Apr 24.

Museum of Comparative Zoology, Harvard University, Cambridge, Massachusetts, United States of America.

Recognition and exploitation of hybrid vigor or heterosis among individual crosses of plants and animals has a long and distinguished history. Its manifestation is influenced by a combination of genetic, epigenetic, phenotypic, and environmental factors. Although heterosis is known to be governed by both dominant and epistatic gene action, its expression is greatly influenced by nonlinear interaction among epigenetic and phenotypic (phenomic) components. Read More

Mol Biol Cell 2019 Apr 24:mbcE18120776. Epub 2019 Apr 24.

Department of Biology and Center for Engineering Mechanobiology, Washington University in St. Louis, St. Louis, MO 63130, USA.

The microtubule-severing enzyme katanin regulates the organization and turnover of microtubule arrays by the localized breakdown of microtubule polymers. In land plants, katanin (KTN1) activity is essential for the formation of linearly organized cortical microtubule arrays which determine the axis of cell expansion. Cell biological studies have shown that even though KTN1 binds to the sidewalls of single and bundled microtubules, severing activity is restricted to microtubule crossover and nucleation sites, indicating that cells contain protective mechanisms to prevent indiscriminate microtubule severing. Read More

Insect Sci 2019 Apr 24. Epub 2019 Apr 24.

Department of Entomology, Texas A&M University, College Station, TX, 77843, USA.

Sitodiplosis mosellana, a periodic but devastating wheat pest, relies on wheat spike volatiles as a cue in selecting hosts for oviposition. Insect odorant binding proteins (OBPs) are thought to play essential roles in filtering, binding and transporting hydrophobic odorant molecules to specific receptors. To date, the molecular mechanisms underlying S. Read More

Rapid Commun Mass Spectrom 2019 Apr 24. Epub 2019 Apr 24.

Global Institute for Water Security, School of Environment and Sustainability, University of Saskatchewan, 11 Innovation Boulevard, Saskatoon, SK, S7N 3H5, Canada.

Rationale: The stable isotope compositions of hydrogen and oxygen in water (δ H and δ O values) have been widely used to investigate plant water sources, but traditional isotopic measurements of plant waters are expensive and labor intensive. Recent work with direct vapor equilibration (DVE) on laser spectroscopy has shown potential to sidestep limitations imposed by traditional methods. Here, we evaluate DVE analysis of plants with a focus on spectral contamination introduced by organic compounds. Read More

Environ Toxicol Chem 2019 Apr 24. Epub 2019 Apr 24.

Department of Civil and Environmental Engineering, Colorado School of Mines, Golden, CO, USA.

Produced water (PW) from oil and gas operations is considered a potential resource for food crop irrigation due to increasing water scarcity in dryland agriculture. However, efforts to employ PW for agriculture have been met with limited success. Here, a greenhouse study was performed to evaluate the effects of PW on physiological and morphological traits of spring wheat (Triticum aestivum). Read More

Physiol Plant 2019 Apr 24. Epub 2019 Apr 24.

School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, Sichuan, 621010, People's Republic of China.

WRKY transcription factors play a key role in the tolerance of biotic and abiotic stresses across various crop species, but the function of some WRKY genes, particularly in tomato, remains unexplored. Here we characterize the roles of a previously unstudied WRKY gene, SlWRKY8, in the resistance to pathogen infection and the tolerance to drought and salt stresses. Expression of SlWRKY8 was up-regulated upon Pseudomonas syringae pv. Read More

Cryo Letters 2019 Mar/Apr;40(2):113-122

Dept. of Well-being Resources, Sunchon National University, Suncheon, 57922, Korea.

Background: Aster altaicus var. uchiyamae Kitam is an endemic and endangered species in urgent need of a comprehensive conservation strategy.

Objective: To develop an efficient cryopreservation protocol using in vitro shoot tips to complement traditional conservation approaches in case seeds are not available or insufficient for conservation programs. Read More

Cryo Letters 2019 Mar/Apr;40(2):103-112

USDA-ARS National Laboratory for Genetic Resources Preservation, Fort Collins, CO 80521, USA.

Background: Cryopreservation has been considered a preferred method for the long-term storage of plant germplasm, especially to efficiently conserve and maintain the genetic integrity of genebank materials. Droplet-vitrification (DV) procedures have been developed to cryopreserve Vitis shoot tips from in vitro-grown plants.

Objective: This research focused on optimizing shoot tip sizes for DV and the feasibility of using cryo-plates for Vitis cryopreservation. Read More

J Gen Virol 2019 Apr 24. Epub 2019 Apr 24.

3​Wheat, Sorghum, and Forage Research Unit, USDA-ARS, Lincoln, NE 68583, USA.

Wheat streak mosaic virus (WSMV; genus Tritimovirus; family Potyviridae) is an economically important wheat virus that is transmitted by the wheat curl mite (WCM; Aceria tosichella Keifer) in a persistent manner. Virus-vector coevolution may potentially influence vector gene expression to prolong viral association and thus increase virus transmission efficiency and spread. To understand the transcriptomic responses of WCM to WSMV, RNA sequencing was performed to assemble and analyse transcriptomes of WSMV viruliferous and aviruliferous mites. Read More

Phytopathology 2019 Apr 24. Epub 2019 Apr 24.

University of Delhi, 28742, Gut Biology Laboratory, Room No. 117, Department of Zoology, Delhi, Delhi, India ;

Begomoviruses are the largest group of plant viruses, transmitted exclusively by the whitefly, (Gennadius) in a persistent, circulative and non-propagative manner. Begomoviruses, in association with cause enormous loss to world agricultural crops. Transmission, retention and circulation of begomovirus in are facilitated by its interaction with several proteins of the insect and its endosymbionts. Read More

Phytopathology 2019 Apr 24. Epub 2019 Apr 24.

Michigan State University, Plant Pathology Dept , 107 CIPS Bldg , East Lansing, Michigan, United States , 48824 ;

Current methods to quantitatively assess fungicide sensitivity for a diverse range of oomycetes are slow and labor intensive. Microtiter based assays can be used to increase throughput. However, many factors can affect their quality and reproducibility. Read More

Radiat Res 2019 Apr 24. Epub 2019 Apr 24.

a   Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, PR China.

Radiation-induced bystander effects (RIBE) entail a cascade of bystander signals produced by the hit cells to the neighboring cells to regulate various biological processes including DNA damage repair. However, there is little clarity regarding the effect of radiation-targeted volume (hit cell amount) on the DNA repair potential of the bystander cells. This is especially important to understand in the context of the whole organism, where the target usually consists of multiple types of cells/tissues. Read More

Biosci Biotechnol Biochem 2019 Apr 24:1-9. Epub 2019 Apr 24.

b Zhejiang Provincial Top Discipline of Biological Engineering (Level A) , Zhejiang Wanli University , Ningbo , China.

Citrus plants are rich in flavonoids and beneficial for lipid metabolism. However, the mechanism has not been fully elucidated. Both citrus peel flavonoid extracts (CPFE) and a mixture of their primary flavonoid compounds, namely, nobiletin, tangeretin and hesperidin, citrus flavonoid purity mixture (CFPM), were found to have lipid-lowering effects on oleic acid-induced lipid accumulation in HepG2 cells. Read More

J Med Food 2019 Apr 24. Epub 2019 Apr 24.

3 Frutarom Switzerland Ltd., Scientific Affairs BU Health, Wädenswil, Switzerland.

Majority of men are affected by symptomatic benign prostatic hyperplasia (BPH) from a certain age. Botanical extracts are frequently used in the early management of the symptoms. In a single-arm, mono-center pilot study, the effects of a proprietary oil-free hydroethanolic pumpkin seed extract on the symptoms of BPH were investigated. Read More

Nutr Cancer 2019 Apr 24:1-10. Epub 2019 Apr 24.

b Department of Clinical and Experimental Medicine - Section of Applied Biology and Genetics , University of Pisa , Pisa , Italy.

Genistein is one of the several known isoflavonic phytoestrogens found in a number of plants, with soybeans and soy products being the primary food source. The aim of the study is to evaluate if genistein is able to exert antineoplastic action in primary human papillary thyroid cancer (PTC) cells. Thyroid tissues were treated with genistein (1-10-50-100 µM). Read More

DNA Cell Biol 2019 Apr 24. Epub 2019 Apr 24.

1 Division of Biochemistry, ICAR-Indian Agricultural Research Institute, New Delhi, India.

Plants, being sessile organisms, have evolved several dynamic mechanisms of gene regulation. Epigenetic modification especially cytosine methylation and demethylation actively regulates the expression of genes. To understand the role of cytosine methylation during isoflavonoid biosynthesis and accumulation, we performed cytosine methylation analysis in the coding region of two isoforms and gene, in two contrasting soybean genotypes differing in total isoflavone content (NRC37: high isoflavone; and NRC7: low isoflavone). Read More

Crit Rev Food Sci Nutr 2019 Apr 24:1-13. Epub 2019 Apr 24.

a Facultad de Ingeniería Agroindustrial , Universidad Pontificia Bolivariana , Medellín , Colombia.

New trends in food are emerging in response to consumer awareness of the relationship between food and health, which has triggered the need to generate new alternatives that meet the expectations of the market. Revolutionary fields such as nanotechnology have been used for the encapsulation of nutritional ingredients and have great potential for the management of food additives derived from fruits and plant species. Turmeric, a spice that has been used as a dyeing agent, is recognized for its properties in Ayurveda medicine. Read More

Ecol Appl 2019 Apr 24:e01911. Epub 2019 Apr 24.

School of Biological Sciences, University of Queensland, St Lucia, 4072, Queensland, Australia.

In many of the world's arid regions there has been a dramatic increase in grazing pressure with herds of livestock sustained by the provision of artificial water points. In these systems it has been suggested that grazing-sensitive plant species will have contracted to refuges distant from water points where grazing impacts are low. This association was tested using a large dataset of presence-absence records for rare plant species throughout the north-eastern Australian arid zone. Read More

Plant J 2019 Apr 24. Epub 2019 Apr 24.

Department of Botany and Plant Sciences, University of California, Riverside, CA, 92521, USA.

Cowpea (Vigna unguiculata [L.] Walp.) is a major crop for worldwide food and nutritional security, especially in sub-Saharan Africa, that is resilient to hot and drought-prone environments. Read More

Braz J Biol 2019 Apr 18. Epub 2019 Apr 18.

Instituto Federal de Educação, Ciência e Tecnologia do Triângulo Mineiro - Campus Uberlândia Centro, Rua Blanche Galassi, Morada da Colina, CEP 38411-104, Uberlândia, MG, Brasil.

Essential oils, which may be extracted from several parts of plants, have different biological activities. The Brazilian Cerrado has a large variety of plants that yield essential oils, even though many have not been studied yet. Taking into account the biodiversity of this biome, this study aimed at evaluating the antiproliferative activity of essential oils extracted from three species of plants of the Cerrado in Goiás state: Campomanesia adamantium (Cambess. Read More

Braz J Biol 2019 Oct-Dec;79(4):742-748. Epub 2019 Apr 18.

Department of Biotechnology, Lahore College for Women University - LCWU, Lahore, Pakistan.

Citrus fruit production occupies a place of considerable importance in the economy of the world including Pakistan. Tristeza disease caused by Citrus Tristeza Virus (CTV) exists in various forms that may or may not cause symptoms in the plants. The bioactive compounds and antioxidants are naturally present in plants and provide a defense mechanism that is generally accelerated in response to a stress. Read More

Braz J Biol 2019 Oct-Dec;79(4):629-638. Epub 2019 Jan 14.

Microbial Biotechnology and Medical Toxicology Laboratory, Department of Zoology, University of Azad Jammu and Kashmir, Muzaffarabad-13100, Pakistan.

Background: Hepatocellular carcinoma is the most frequent primary malignancy of liver and accounts for as many as one million deaths worldwide in a year.

Objectives: The aim of the present study was to evaluate the anti-cancerous efficiency of Bergenia ciliata rhizome against diethylnitrosoamine induced hepatocarcinogenesis in Balb C mice.

Methods: One percent diethylnitrosoamine was prepared by using 99 ml of normal saline NaCl (0. Read More

Int J Phytoremediation 2019 Apr 24:1-12. Epub 2019 Apr 24.

a Plant Physiology and Biochemistry Division, Department of Botany , University of Calicut , Malappuram , Kerala , India.

Effect of cadmium (Cd) on the primary metabolic activities and elemental distribution in roots was explored in Acanthus ilicifolius L., a halophyte with phytostabilization potential. The rate of photosynthesis decreased in the CdCl treated plants and this reduction was mainly attributed to the reduction of leaf area, photosynthetic pigments, impaired gaseous exchange caused by the stomatal closure and tissue water status. Read More

Int J Phytoremediation 2019 Apr 24:1-5. Epub 2019 Apr 24.

b Faculty of Biology and Soil Sciences, Irkutsk State University , Irkutsk , Russia.

The article dwells upon identifying the effect of cadmium on the roots of beetroot. The exposure effects of various concentrations of cadmium were studied at different levels of the plant organization (tissue pieces, organelles, membrane vesicles). The effect was noted only at a concentration of 100 μm. Read More

Int J Phytoremediation 2019 Apr 24:1-7. Epub 2019 Apr 24.

a Soil and Environmental Sciences Division , Nuclear Institute for Agriculture and Biology (NIAB) , Faisalabad , Pakistan.

Phytoremediation of heavy metal contaminated soils represents a promising technique and salt-tolerant hyperaccumulators for multiple metals are the need of time. Therefore, phytoremediation potential of four salt-tolerant grass species [Dhab (Desmostachya bipinnata), Kallar (Leptochloa fusca), Para (Brachiaria mutica) and Sporobolus (Sporobolus arabicus Boiss)] was evaluated for cadmium (Cd) and lead (Pb) in a hydroponic study. The plants were harvested after a growth period of 3 months in a nutrient solution containing different levels of Cd (0, 5, and 25 mg L) and Pb (0, 25, and 125 mg L). Read More

Int J Phytoremediation 2019 Apr 24:1-7. Epub 2019 Apr 24.

a School of Arts, Sciences and Humanities , University of São Paulo , Sao Paulo , Brazil.

Treatment of landfill leachate is a challenge due to its complex chemical composition and high recalcitrance and because of high costs for conventional wastewater treatment. In our study, leachate from the Quitaúna Landfill, Sao Paulo Metropolitan Region, Brazil, was treated at a laboratory scale with a horizontal subsurface flow constructed treatment wetland (HF-CTW) operating under a recirculation regime. Two units planted with Heliconia psittacorum (HP) and Cyperus papyrus (CP), and one unplanted control unit were assessed. Read More

Int J Phytoremediation 2019 Apr 24:1-11. Epub 2019 Apr 24.

a a Cold Regions Research and Engineering Laboratory, Biogeochemical Sciences Branch , U.S. Army Engineer Research and Development Center , Hanover , NH , USA.

Decades of live-fire training exercises have left millions of acres of military training lands contaminated with various munitions constituents such as dinitrotoluene. Those that pose a threat to higher organisms due to their toxicity and mobility in the soil are of particular concern. Plants aid in the biodegradation and phytoextraction of contaminants, and site-specific ecotoxicity determinations are critical to inform effective remediation strategy. Read More

Chemistry 2019 Apr 23. Epub 2019 Apr 23.

Key Laboratory of Polyoxometalate Science of the Ministry of Education, Faculty of Chemistry, Northeast Normal University, CHINA.

Utilization of porous materials for gas capture and separation has been a hot topic for researchers. Acetylene (C2H2) removal from ethylene (C2H4) exerts an enormous function on refining and petrochemical industry since C2H2 impurity deactivates the catalysts and further terminates polymerization of C2H4. Nowadays carbon dioxide (CO2) emission from power plants contributes to the global climate change and threatens the survival of lives on this planet. Read More

J Cell Biochem 2019 Apr 23. Epub 2019 Apr 23.

Medicinal Plants Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.

Cholestatic liver disease is recognized by extreme collagen formation and deposition, which is mediated by free radicals. The aim of the current study was to investigate the probable hepatoprotective effects of hydroalcoholic extract of watercress (WC) against oxidative stress and liver injury in bile duct ligation (BDL)- induced cholestatic rats. A total of 32 male Wistar rats were divided into four groups; sham control (SC), BDL, SC + hydroalcoholic extract of WC and BDL + hydroalcoholic extract of WC. Read More

Biomed Chromatogr 2019 Apr 24:e4560. Epub 2019 Apr 24.

Department of Chemistry, Faculty of Science, Van Yüzüncü Yıl University, Van, Turkey.

Glutathione reductase (GR, E.C. 1. Read More

J Nat Med 2019 Apr 23. Epub 2019 Apr 23.

Division of Food Additives, National Institute of Health Sciences, Tokyo, Japan.

Perillaldehyde (PRL) is one of the essential oil components derived from perilla plants (Perilla frutescens Britton) and is a characteristic compound of the traditional medicine "perilla herb ()" listed in the The Japanese Pharmacopoeia, 17th edition (JP17). HPLC using an analytical standard of PRL has been used to quantitatively determine the PRL content in perilla herb. However, PRL reagents have been reported to decompose easily. Read More

Environ Sci Pollut Res Int 2019 Apr 24. Epub 2019 Apr 24.

Agro-Environmental Protection Institute, Ministry of Agriculture and Rural Affairs, Tianjin, 300191, China.

In this study, a novel Fe-Mn-Ce oxide-modified biochar composite (FMCBC) was synthesized via pyrolysis to enhance the adsorption capacity of biochar (BC). Scanning electron microscopy-energy-dispersive X-ray spectroscopy confirmed that Fe, Mn, and Ce were successfully loaded onto the surface of the BC. A series of adsorption experiments showed that the FMCBC exhibited improved adsorption of As(III) in an aqueous environment. Read More

Environ Sci Pollut Res Int 2019 Apr 24. Epub 2019 Apr 24.

Food Health Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

The toxic impacts of CuO nanoparticles (NPs) on the marine phytoplankton Nannochloropsis oculata were evaluated by measuring a number of biological parameters. Exposure to different concentrations of CuO-NPs (5-200 mg/L) significantly decreased the growth and content of chlorophyll a of N. oculata. Read More

Environ Sci Pollut Res Int 2019 Apr 23. Epub 2019 Apr 23.

Key Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin Provincial Key Laboratory of Water Resources and Environment, College of New Energy and Environment, Jilin University, Changchun, 130012, China.

As a result of the widespread use of antibiotics, a large amount of excretions from human and animals, containing antibiotic residues, is discharged into aquatic environments, leading to potential adverse effects on the ecosystems' health. These residues' impact on seasonally ice-covered rivers remains under investigated. To understand the environmental fate of antibiotics with high-detection frequencies and concentration levels, sulfamethoxazole, lincomycin, and florfenicol were used as models in the present study. Read More

AAPS J 2019 Apr 23;21(4):57. Epub 2019 Apr 23.

Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548, Coimbra, Portugal.

Resveratrol (RSV) is a polyphenol endowed with potential therapeutic effects in chronic diseases, particularly in cancer, the second leading cause of death worldwide in the twenty-first century. The advent of nanotechnology application in the field of drug delivery allows to overcome the constrains associated with the conventional anticancer treatments, in particular chemotherapy, reducing its adverse side effects, off target risks and surpassing cancer multidrug chemoresistance. Moreover, the use of nanotechnology-based carriers in the delivery of plant-derived anticancer agents, such as RSV, has already demonstrated to surpass the poor water solubility, instability and reduced bioavailability associated with phytochemicals, improving their therapeutic activity, thus prompting pharmaceutical developments. Read More