1,128,821 results match your criteria Plant Poisoning Alkaloids – Quinolizidine and Isoquinoline


One Health approach to improve the malaria elimination programme in Henan Province.

Adv Parasitol 2022 26;116:153-186. Epub 2022 Mar 26.

Henan Center for Disease Control and Prevention, Zhengzhou, Henan, PR China. Electronic address:

One Health is a collaborative, multi-sectoral, trans-disciplinary approach with the goal of achieving optimal health outcomes by recognizing the interconnection between people, animals, plants, and the environment and determining how this relates to the control of infectious diseases such as malaria, schistosomiasis and so on. Malarias caused by Plasmodium that commonly infects female Anopheles mosquitoes, which feed on human blood and act as a disease vector. It has been a worldwide important public health problem from ancient times. Read More

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The hormetic dose-risks of polymethylmethacrylate nanoplastics on chlorophyll a fluorescence transient, lipid composition and antioxidant system in Lactuca sativa.

Environ Pollut 2022 Jun 22:119651. Epub 2022 Jun 22.

Graduate School of Natural and Applied Sciences, Nanotechnology and Advanced Materials, Selcuk University, Selcuklu, 42130, Konya, Turkey. Electronic address:

Nanoplastic pollution has become an increasing problem due to over-consumption and degradation in ecosystems. A little is known about ecological toxicity and the potential risks of nanoplastics on plants. To better comprehend the hormetic effects of nanoplastics, the experimental design was conducted on the impacts of polymethyl methacrylate (PMMA) on water status, growth, gas exchange, chlorophyll a fluorescence transient, reactive oxygen species (ROS) content (both content and fluorescence visualization), lipid peroxidation and antioxidant capacity (comparatively between leaves and roots). Read More

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Global PBDE contamination in cetaceans. A critical review.

Environ Pollut 2022 Jun 22:119670. Epub 2022 Jun 22.

Department of Instrumental Analysis and Environmental Chemistry, Institute of Organic Chemistry (IQOG-CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.

This review summarizes the most relevant information on PBDEs' occurrence and their impacts in cetaceans at global scale, with special attention on the species with the highest reported levels and therefore the most potentially impacted by the current and continuous release of these substances. This review also emphasizes the anthropogenic and environmental factors that could increase concentrations and associated risks for these species in the next future. High PBDE concentrations above the toxicity threshold and stationary trends have been related to continuous import of PBDE-containing products in cetaceans of Brazil and Australia, where PBDEs have never been produced. Read More

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A Comprehensive Overview of Nanotechnology in Sustainable Agriculture.

J Biotechnol 2022 Jun 22. Epub 2022 Jun 22.

Department of Chemical Engineering, University of Petroleum and Energy Studies, Dehradun, Uttarakhand 248007, India. Electronic address:

Plant nutrition is crucial in crop productivity and providing food security to the ever-expanding population. Application of chemical/biological fertilizers and pesticides are the mainstays for any agricultural economy. However, there are unintended consequences of using chemical fertilizers and pesticides. Read More

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A reverse-ecology framework to uncover the potential metabolic interplay among 'Candidatus Liberibacter' species, Citrus hosts and psyllid vector.

Gene 2022 Jun 22:146679. Epub 2022 Jun 22.

Grupo de Genômica Evolutiva Microbiana, Laboratório de Genética Molecular de Microrganismos, Departamento de Microbiologia, Instituto de Biotecnologia Aplicada à Agropecuária, Universidade Federal de Viçosa, Minas Gerais, Brazil. Electronic address:

'Candidatus Liberibacter' species have developed a dependency on essential nutrients and metabolites from the host cell, as a result of substantial genome reduction. Still, it is difficult to state which nutrients they acquire and whether or not they are metabolically reliant. We used a reverse-ecology model to investigate the potential metabolic interactions of 'Ca Liberibacter' species, Citrus, and the psyllid Diaphorina citri in the huanglongbing disease pyramid. Read More

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Identification and functional characterization of mRNAs that exhibit stop codon readthrough in Arabidopsis thaliana.

J Biol Chem 2022 Jun 22:102173. Epub 2022 Jun 22.

Department of Biochemistry, Indian Institute of Science, Bengaluru, India. Electronic address:

Stop codon readthrough (SCR) is the process of continuation of translation beyond the stop codon, generating protein isoforms with C-terminal extensions. SCR has been observed in viruses, fungi, and multicellular organisms, including mammals. However, SCR is largely unexplored in plants. Read More

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Furostanol saponins from Asparagus racemosus as potential hypoglycemic agents.

Phytochemistry 2022 Jun 22:113286. Epub 2022 Jun 22.

Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, BS-10/1, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India; Sophisticated Analytical Instrument Facility & Research, CSIR-Central Drug Research Institute, BS-10/1, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, U.P., India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, U.P., India. Electronic address:

Bioactivity guided phytochemical investigation led to isolation of six undescribed furostanol saponins, furoasparoside A-F along with five known compounds, gallic acid, methyl gallate, quercetin-3-O-β-glucopyranoside, liquiritigenin 4-O-β-apiofuranosyl-(1 → 2)-β-glucopyranoside and β-glucogallin for the first time from the roots of Asparagus racemosus. Isolated saponins were screened for their antidiabetic potential in L6-GLUT4myc myotubes in vitro followed by an in vivo evaluation in streptozocin-induced diabetic rats and db/db mice. Furoasparoside E produced a notable decrease in the postprandial blood glucose profile, in leptin receptor-deficient db/db mice, type 2 diabetes model. Read More

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A study on exposure to greenspace during pregnancy and lipid profile in cord blood samples.

Environ Res 2022 Jun 22:113732. Epub 2022 Jun 22.

ISGlobal, Barcelona, Spain; Pompeu Fabra University, Barcelona, Catalonia, Spain; Ciber on Epidemiology and Public Health (CIBERESP), Madrid, Spain. Electronic address:

Although evidence reporting the beneficial associations of prenatal greenspace exposure with pregnancy outcomes is increasing, there is still a lack of evidence on the potential association of such exposure to greenspace on fetal lipid profile. We aimed to first-time investigate the associations between prenatal exposure to greenspace and lipid levels in the cord blood. The present study was based on data from 150 expectant mothers, residents of Sabzevar city in Iran (2018). Read More

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Acute toxicity of broflanilide on neurosecretory system and locomotory behavior of zebrafish (Danio rerio).

Chemosphere 2022 Jun 22:135426. Epub 2022 Jun 22.

Plant Protection College, Shenyang Agricultural University, Shenyang, China. Electronic address:

Broflanilide, a novel meta-diamide insecticide, possesses moderate acute toxicity to zebrafish, with a 96-h median lethal concentration (96-LC) of 0.76 mg/L. However, its effect on fish behavior and the underlying mechanisms are still unclear. Read More

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Lithium occurrence in drinking water sources of the United States.

Chemosphere 2022 Jun 22:135458. Epub 2022 Jun 22.

Nanosystems Engineering Research Center for Nanotechnology-Enabled Water Treatment, School of Sustainable Engineering and the Built Environment, Arizona State University, Tempe, AZ, 85287-3005, USA. Electronic address:

Lithium (Li) is listed in the fifth Unregulated Contaminant Monitoring Rule (UCMR 5) because insufficient exposure data exists for lithium in drinking water. To help fill this data gap, lithium occurrence in source waters across the United States was assessed in 21 drinking water utilities. From the 369 samples collected from drinking water treatment plants (DWTPs), lithium ranged from 0. Read More

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Physiologically relevant curcuminoids inhibit angiogenesis via VEGFR2 in human aortic endothelial cells.

Food Chem Toxicol 2022 Jun 22:113254. Epub 2022 Jun 22.

Laboratory of Food and Health, Research Group on Quality, Safety and Bioactivity of Plant Foods, Dept. Food Science and Technology, CEBAS-CSIC, P.O. Box 164, 30100. Campus de Espinardo, Murcia, Spain.

Angiogenesis is a complex process encompassing endothelial cell proliferation, migration, and tube formation. While numerous studies describe that curcumin exerts antitumor properties (e.g. Read More

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The in vitro and in vivo antibacterial activities of uniflorous honey from a medical plant, Scrophularia ningpoensis Hemsl., and characterization of its chemical profile with UPLC-MS/MS.

J Ethnopharmacol 2022 Jun 22:115499. Epub 2022 Jun 22.

College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, 350002, China; College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, China. Electronic address:

Ethnopharmacological Relevance: According to the Compendium of Materia Medica, honey has been used as a traditional medicine in treatment against mucositis, tinea, hemorrhoids and psoriasis. In complementary medicine, due to its significant antimicrobial activity, honey has been widely used as a remedy for skin wounds and gastrohelcosis for thousands of years.

Aim Of The Study: This study is aimed at exploring the antimicrobial activity and mechanisms of honey sourced from medical plants, and revealing the composition-activity relationship, to facilitate their complementary and alternative application in the therapy of bacterial infectious diseases. Read More

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Agrimonia eupatoria L.: An integrative perspective on ethnomedicinal use, phenolic composition and pharmacological activity.

J Ethnopharmacol 2022 Jun 22:115498. Epub 2022 Jun 22.

Univ Coimbra, Faculty of Pharmacy, Laboratory of Pharmacology and Pharmaceutical Care, 3000-548, Coimbra, Portugal; Univ Coimbra, Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR), 3000-548, Coimbra, Portugal; Univ Coimbra, Center for Innovative Biomedicine and Biotechnology, 3000-548, Coimbra, Portugal. Electronic address:

Ethnopharmacological Relevance: Agrimonia eupatoria L., a plant which belongs to the Rosaceae family, is widespread in temperate regions, particularly throughout the northern hemisphere. In folk medicine, this plant species has been used for its astringent, anti-inflammatory, analgesic and hypotensive properties as well as in gastrointestinal disorders. Read More

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Safety evaluation and bioassay-guided isolation of antimycobacterial compounds from Morella salicifolia root ethanolic extract.

J Ethnopharmacol 2022 Jun 22:115501. Epub 2022 Jun 22.

Department of Biological and Pre-clinical Studies, Institute of Traditional Medicine, Muhimbili University of Health & Allied Sciences, Dar es Salaam, Tanzania.

Ethnopharmacological Relevance: Although the available medicines can cure almost all tuberculosis drug-susceptible patients some problems including the emergence of multi-drug resistant and extensively drug-resistant strains press for the need of new anti-TB medicines. Morella salicifoliais a common plant that is widely used in traditional medicine for managing HIV and AIDS-related conditions including tuberculosis but no studies have been done to evaluate its safety and efficacy.

Aim Of The Study: This study was designed to investigate the antimycobacterial activity and safety of M. Read More

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Anaerobic biogas formation from crops' agricultural residues - Modeling investigations.

Bioresour Technol 2022 Jun 22:127497. Epub 2022 Jun 22.

Ain Shams University (ASU), Energy Technology and Climate Change Laboratory, Faculty of Engineering, Elsarayat Street 1, Cairo / Abbasia, Egypt.

The cultivation of field crops necessarily produces large quantities of organic residues, which could be used for the production of biogas. However, this is only successfully possible if the operators of such biogas plants have sufficient expertise in running these plants, e.g. Read More

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Six decades of field observations reveal how anthropogenic pressure changes the coverage and community of submerged aquatic vegetation in a eutrophic lake.

Sci Total Environ 2022 Jun 22:156878. Epub 2022 Jun 22.

Taihu Laboratory for Lake Ecosystem Research, State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, 73 East Beijing Road, Nanjing 210008, PR China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

Six decades field observation data series on submerged aquatic vegetation (SAV), water level and water quality from Lake Taihu were compiled to reveal the dynamics in coverage and species composition of SAV and their anthropogenic drivers. We found that both SAV species composition and coverage area declined significantly in Lake Taihu during the period, and the increasing nutrient levels and water level as well as decreasing water clarity were responsible for these change trends. Specifically, the decrease in species richness could be particularly well predicted by total nitrogen (TN) and the ratio of water clarity (i. Read More

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Automated identification and quantification of invisible microplastics in agricultural soils.

Sci Total Environ 2022 Jun 22:156853. Epub 2022 Jun 22.

State Key Joint Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering, Peking University, Beijing 100871, China; Marine Institute for Bioresources and Environment, Peking University Shenzhen Institute, Shenzhen, Guangdong 518057, China. Electronic address:

Microplastics in agricultural soils have become the research hotspot in recent years, however, the quantitative methods based on the traditional visual inspection may have a high false detection rate. Here we combined the laser direct infrared (LDIR) and Fourier-transform infrared (FTIR) methods to investigate the microplastics in farmland with long-term agricultural activities. The results showed that the total abundance of microplastics reached 1. Read More

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Seasonal variation, source contribution, and impact factors of biogenic organic aerosols in PM in Nanjing, China.

Sci Total Environ 2022 Jun 22:156875. Epub 2022 Jun 22.

Institute of Meteorological Development and Planning, China Meteorological Administration, Beijing 100081, China.

In this study, a liquid chromatography-mass spectrometry (HPLC-ESI-MS/MS) was used to develop a rapid method to detect carbohydrates (one anhydrosugar, five sugars, and four sugar alcohols) and monoterpene secondary organic aerosol (SOA) tracers in the atmosphere, successfully applied to 139 atmospheric aerosol samples in Nanjing in 2019. Anhydrosugar (levoglucosan) is the most abundant carbohydrate in the atmospheric environment, with an annual mean concentration of 103.96 ng m. Read More

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Transcriptome analysis and screening of putative sex-determining genes in the invasive pest, Frankliniella occidentalis (Thysanoptera: Thripidae).

Comp Biochem Physiol Part D Genomics Proteomics 2022 Jun 11;43:101008. Epub 2022 Jun 11.

College of Horticulture and Plant Protection, Institute of Applied Entomology, Yangzhou University, Yangzhou 225009, China; Joint International Research Laboratory of Agriculture and Agri-Product Safety, The Ministry of Education, Yangzhou University, Yangzhou, China. Electronic address:

The invasive insect pest, Frankliniella occidentalis, is a well-known vector that transmits a variety of ornamental and vegetable viruses. The mechanistic basis of sex determination in F. occidentalis is not well understood, and this hinders our ability to deploy sterile insect technology as an integrated pest management strategy. Read More

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Development and sensory test of a dairy product with ACE inhibitory and antioxidant peptides produced at a pilot plant scale.

Food Chem 2022 Jun 11;394:133459. Epub 2022 Jun 11.

Departamento de Química Analítica e Alimentaria, Universidade de Vigo, Laboratorio de Bioquímica, 32004 Ourense, Spain.

A scale-up process was carried out to obtain potent bioactive peptides from whey protein through a simple hydrolysis process. The scale-up was satisfactory, with results similar to those obtained at lab scale: a fraction of peptides < 1 kDa with ACE inhibitory activity of 18.44 ± 2. Read More

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Multi-objective utilization of wood waste recycled from construction and demolition (C&D): Products and characterization.

Waste Manag 2022 Jun 22;149:228-238. Epub 2022 Jun 22.

Alpha Thermal Process, LLC 505, Mennonite Road Royersford, PA 19468, USA.

Producing energy and higher value bio-products from waste materials has been proposed as an economically viable opportunity in the renewable energy sector. However, several challenges associated with the integrated biomass conversion processes remain to be resolved. The present study introduces a multi-faceted plant production of thermal energy and biochar from construction and demolition (C&D) wood chips. Read More

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Steroid glycosides isolated from Paris polyphylla var. chinensis aerial parts and paris saponin II induces G1/S-phase MCF-7 cell cycle arrest.

Carbohydr Res 2022 Jun 15;519:108613. Epub 2022 Jun 15.

College of Pharmacy, Korea University, Sejong, 30019, Republic of Korea. Electronic address:

In our previous research on Vietnamese medicinal plants, we found that the ethanolic extract of the aerial parts of Paris polyphylla var. chinensis exhibited cytotoxic effects in vitro in the MCF-7 human cancer cell line. Here, we used combined chromatographic separations to isolate six compounds including a new steroid glycoside, paripoloside A (3), and five known compounds, from the butanol extract of the aerial parts of P. Read More

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Temperature mediated the balance between stochastic and deterministic processes and reoccurrence of microbial community during treating aniline wastewater.

Water Res 2022 Jun 13;221:118741. Epub 2022 Jun 13.

School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, China; Key Laboratory of Biometallurgy, Ministry of Education, Changsha 410083, China. Electronic address:

Seasonal temperature changes significantly affect microbial community diversity, composition, and performance in wastewater treatment plants. However, the community assembly mechanisms under seasonal temperature variations remain unclear. Here, we carried out temperature cycling experiments (30 °C, 35 °C, 37 °C, 40 °C, 42 °C, 45 °C, 40 °C, and 30 °C) to investigate how temperature impacts microbial performance and co-occurrence network and how assembly processes determine the structure and function of microbial communities during treating aniline wastewater. Read More

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Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype.

Phytomedicine 2022 Jun 8;104:154252. Epub 2022 Jun 8.

Department of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, China. Electronic address:

Background: Despite the substantial amount of efforts made to reduce morbidity and improve respiratory management, asthma control remained a major challenge for severe patients. Plant isoflavones, one of the most estrogenic compounds, are considered a potential alternative therapy for asthma. Iristectorigenin A, a naturally occurring isoflavone, is extracted from a variety of medical plants and its biological activity has not been reported previously. Read More

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Removal of contaminants of emerging concern from secondary-effluent reverse osmosis retentates by continuous supercritical water oxidation- parametric study and conceptual design.

J Hazard Mater 2022 Jun 15;437:129379. Epub 2022 Jun 15.

Faculty of Civil and Environmental Engineering, Technion, Haifa 32000, Israel. Electronic address:

The continuous removal of TOC and the degradation efficiency of carbamazepine and 17β-estradiol were investigated using actual secondary municipal-effluent RO-retentate solutions. A specific set of operating parameters were applied within the supercritical water oxidizing conditions: temperature range 420-480 °C, 25.1 MPa, hydraulic retention time (HRT) of 1-2 min, excess oxidant molar-ratio of 3-10 and presence of a homogenous catalyst (IPA) at 50-100 mg/L. Read More

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Spatial and temporal prediction of radiation dose rates near Fukushima Daiichi Nuclear Power Plant.

J Environ Radioact 2022 Jun 22;251-252:106946. Epub 2022 Jun 22.

Japan Atomic Energy Agency, Tokyo, Japan.

In this paper, we have developed a methodology to estimate the spatiotemporal distribution of radiation air dose rates around the Fukushima Daiichi Nuclear Power Plant (FDNPP). In our exploratory data analysis, we found that (1) the temporal evolution of dose rates is composed of a log-linear decay trend and fluctuations of air dose rates that are spatially correlated among adjacent monitoring posts; and (2) the slope of the log-linear environmental decay trend can be represented as a function of the apparent initial dose rates, coordinate position, land-use type, and soil type. From these observations, we first estimated the log-linear decay trend at each location based on these predictors, using the random forest method. Read More

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Phosphatidic acid binds to and stimulates the activity of ARGAH2 from Arabidopsis.

Plant Physiol Biochem 2022 Jun 16;185:344-355. Epub 2022 Jun 16.

Department of Botany, University of Delhi, Delhi, 110007, India. Electronic address:

Phosphatidic acid (PA) has emerged as an important lipid signal during abiotic and biotic stress conditions such as drought, salinity, freezing, nutrient starvation, wounding and microbial elicitation. PA acts during stress responses primarily via binding and translocating target proteins or through modulating their activity. Owing to the importance of PA during stress signaling and developmental stages, it is imperative to identify PA interacting proteins and decipher their specific roles. Read More

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Contrasting mobility of arsenic and copper in a mining soil: A comparative column leaching and pot testing approach.

J Environ Manage 2022 Jun 22;318:115530. Epub 2022 Jun 22.

Department of Environmental Geosciences, Faculty of Environmental Sciences, Czech University of Life Sciences Prague, Kamýcká 129, 16500 Praha 6 Suchdol, Czech Republic; Environmental and Geochemical Sciences Department, The James Hutton Institute, Craigiebuckler, Aberdeen AB158QH, UK.

The remediation of legacy metal(loid) contaminated soils in-situ relies on the addition of [organic] amendments to reduce the mobility and bioavailability of metal(loid)s, improve soil geochemical parameters and restore vegetation growth. Two vermicomposts of food and animal manure waste origin (V and V) were amended to an arsenic (As) and copper (Cu) contaminated mine soil (≤1500 mg kg). Leaching columns and pot experiments evaluated copper and arsenic in soil pore waters, as well as pH, dissolved organic carbon (DOC) and phosphate (PO) concentrations. Read More

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Exposure of white-tailed deer in North America to influenza D virus.

Virology 2022 Jun 17;573:111-117. Epub 2022 Jun 17.

Center for Influenza and Emerging Infectious Diseases, Columbia, MO, USA; School of Medicine, University of Missouri, Columbia, MO, USA; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA; College of Engineering, University of Missouri, Columbia, MO, USA. Electronic address:

Influenza D virus (IDV) infections have been identified worldwide in cattle, swine, camelid, and small ruminants, mostly in domestic livestock. Here we report that the wild white-tailed deer in North America were exposed to IDVs, suggesting IDVs infect a wide range of hosts including wild animal populations. Read More

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Diverse chemical modifications of the chlorogenic acid composition of Viscum combreticola Engl.: A premise for the state of readiness against excessive sunlight exposure.

J Photochem Photobiol B 2022 Jun 17;233:112501. Epub 2022 Jun 17.

Department of Biochemistry and Microbiology, Faculty of Science, Engineering and Agriculture, University of Venda, Private Bag X5050, Thohoyandou 0950, South Africa. Electronic address:

Mistletoe plants that are positioned on the canopy of their hosts are more susceptible to UV radiation exposure. These aerial plants are resistant to damage by UV radiation due the presence of epidermal constituents such as the cuticle, cork layer, trichomes and antioxidant secondary metabolites. In response to the photo-oxidative stress associated with UV exposure, plants generally deploy photo-protective responsive mechanisms that involve the biosynthesis of UV absorbing phenolic compounds such as chlorogenic acids (CGAs). Read More

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