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Gynecol Endocrinol 2019 Feb 20:1-4. Epub 2019 Feb 20.

a Department of Obstetrics , Affiliated Hospital of Qingdao University , Qingdao , China.

Objective: To determine whether maternal plasma human placental lactogen (hPL) mRNA levels can predict abnormally invasive placenta.

Study Design: Sixty-eight singleton pregnant women with prior Cesarean deliveries were classified into three groups: 35 with normal placentation (control group); 21 with placenta previa alone (placenta previa group); 12 with placenta previa and placenta accreta (placenta accreta group). Maternal plasma hPL mRNA concentrations were measured by real-time reverse-transcription polymerase chain reaction Result: The multiple of the median (median, range) for hPL mRNA was significantly higher for the placenta accreta group (2. Read More

Reprod Sci 2019 Feb 19:1933719119828040. Epub 2019 Feb 19.

1 Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, People's Republic of China.

The typical hallmark of placenta accreta spectrum (PAS) disorders is increased implantation site intermediate trophoblast (ISIT) cell numbers. However, the extent of trophoblast proliferation and apoptosis have not been found to differ from those of normal placentation. MicroRNA-125a (miR-125a) induces apoptosis in colon cancer cell by targeting myeloid cell leukemia-1 gene ( MCL1). Read More

Ultrasound Obstet Gynecol 2019 Feb 19. Epub 2019 Feb 19.

Nuffield Department of Women's and Reproductive Health, University of Oxford, UK.

Objectives: To evaluate fetal growth in pregnancies complicated by placenta previa, both with and without PAS, compared to pregnancies with just a low-lying placenta.

Methods: This was a multicentre retrospective cohort study of singleton pregnancies complicated by placenta previa, both with and without placenta accreta spectrum (PAS), for which maternal characteristics, ultrasound estimated fetal weight and birthweight were available. The control group chosen was singleton pregnancies with a low-lying placenta (0. Read More

Placenta 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynecology, Inje University Busan Paik Hospital, Busan, South Korea; Paik Institute for Clinical Research, Inje University Busan Paik Hospital, Busan, South Korea. Electronic address:

Acta Obstet Gynecol Scand 2019 Feb 15. Epub 2019 Feb 15.

Department of Medicine, Solna, Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden.

Introduction: The impact of placenta previa on pregnancy, delivery and infant outcomes has been extensively studied. Less is however known about the possible association of placental location other than previa with pregnancy outcomes. The aim of this study was to investigate if placental location other than previa is associated with adverse pregnancy, delivery and infant outcomes. Read More

Am J Perinatol 2019 Feb 11. Epub 2019 Feb 11.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, Rhode Island.

Objective:  To develop a model to predict cesarean-associated red blood cell transfusion.

Study Design:  Secondary analysis of all cesarean deliveries in the Maternal-Fetal Medicine Units Network Cesarean Registry. Using a split-sample technique, the derivation group was used to identify associated factors and build predictive models, and the validation group was used to estimate classification errors and determine test characteristics. Read More

J Matern Fetal Neonatal Med 2019 Feb 10:1-11. Epub 2019 Feb 10.

a International Peace Maternity & Child Health Hospital , School of Medicine , Shanghai Jiao Tong University , Shanghai , China.

Objective: We aimed to evaluate the relationship between mode of first delivery with subsequent placenta previa, placenta accreta/increta and significant postpartum hemorrhage (PPH).

Method: This retrospective cohort study included women with two consecutive singleton deliveries between 2007-2017 at our institution if the women were nulliparous and delivered at term at the time of first delivery. The first pregnancy delivery mode was classified as (1) vaginal delivery, (2) antepartum caesarean delivery (CD) without labor, or (3) intrapartum CD after onset of labor. Read More

Fetal Diagn Ther 2019 Feb 6:1-6. Epub 2019 Feb 6.

Lis Maternity and Women's Hospital, Sourasky Medical Center, Tel Aviv, Israel.

Objective: We aimed to evaluate the association between second trimester biochemical markers and pathological placentation.

Methods: This was a retrospective case-control study (2007-2014) of singleton gestations at a university-affiliated tertiary center. Women with pathologic placentation were subdivided into three groups: placenta accreta (group A), placenta previa (group B), or both (group C). Read More

BMC Pregnancy Childbirth 2019 Jan 29;19(1):51. Epub 2019 Jan 29.

Department of Epidemiology and Biostatistics, National Institute for Health Development, Hiiu 42, 11619, Tallinn, Estonia.

Background: An increased risk of adverse conditions related to in vitro fertilization (IVF) pregnancies has been repeatedly reported. Our study aimed to summarize outcome differences between pregnancies after IVF and after spontaneous conception (SC) in Estonia.

Methods: Data on all liveborn singletons to primiparas women aged 25-40 years during the period 2005-2014 were obtained from the Estonian Medical Birth Registry. Read More

Zhonghua Fu Chan Ke Za Zhi 2019 Jan;54(1):27-32

Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China.

To evaluate the risk factors and sonographic findings of pregnancies complicated by placenta increta or placenta percreta. Totally, 2 219 cases were retrospectively analyzed from 20 tertiary hospitals in China from January 2011 to December 2015. The data were collected based on the original case records. Read More

J Matern Fetal Neonatal Med 2019 Jan 27:1-6. Epub 2019 Jan 27.

c Department of Medical Informatics and Statistics , Centre Hospitalier Régional d'Orléans , Orleans , France.

Objective: To evaluate the migration of low-placental implantation (LPI) during the third trimester of pregnancy and its effect on delivery and post-partum hemorrhage.

Methods: We conducted a retrospective study at a level 3 maternity center including all cases of placenta previa (PP) and LPI between 1998 and 2014. The distance (d) between cervical internal os (CIO) and placental edge (PE) were measured by vaginal ultrasonography in the third trimester of pregnancy at 32 and 3 weeks after. Read More

Medicine (Baltimore) 2019 Jan;98(4):e14266

Department of Gynecology and Oncology, Maternal and Child Health Hospital of Hubei Province, Affiliated Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Rationale: It is very difficult to treat patients with placenta previa who underwent pregnancy termination and suffered antenatal massive hemorrhage in the 2nd trimester.

Patient Concerns: In this study, case 1 was with fetal malformation of 18-trisomy syndrome at gestation of 19 weeks + 2 days, case 2 was with fetal malformation of 18-trisomy syndrome at gestation of 22 weeks + 1 day, and case 3 was for intrauterine fetal death at gestation of 27 weeks. All the 3 cases were completely placenta previa. Read More

Exp Ther Med 2019 Feb 6;17(2):1492-1496. Epub 2018 Dec 6.

Department of Interventional Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.

Postpartum hemorrhage is considered to be a serious complication in patients with pernicious placenta. Approaches employing abdominal aortic balloon occlusion to control hemorrhage are extremely effective for such patients. The present study analyzed 9 patients with pernicious placenta previa in a single hospital from June 2016 to November 2017. Read More

J Womens Health (Larchmt) 2019 Jan 24. Epub 2019 Jan 24.

Department of Obstetrics and Gynecology, School of Medicine, University of Virginia, Charlottesville, Virginia.

Introduction: To determine whether maternal human papillomavirus (HPV) infection is associated with preterm premature rupture of membranes (PPROM).

Materials And Methods: We conducted a retrospective cohort study of singleton deliveries at our institution from 2010 to 2015. Women, ages 16-49, with HPV genotyping or cervical cytology results 3 years before delivery were included. Read More

Zhongguo Dang Dai Er Ke Za Zhi 2019 Jan;21(1):6-10

Department of Neonatology, Hubei Maternal and Child Health Care Hospital, Wuhan 430070, China.

Objective: To investigate the incidence of neonatal asphyxia and possible contributing factors for the development of severe asphyxia in Hubei Enshi Tujia and Miao Autonomous Prefecture, China.

Methods: A total of 16 hospitals in Hubei Enshi Tujia and Miao Autonomous Prefecture were selected as research centers. A retrospective analysis was performed for the clinical data of 22 294 live births in these 16 hospitals from January to December, 2016 to investigate the incidence rate of neonatal asphyxia and possible contributing factors for the development of severe asphyxia. Read More

J Obstet Gynaecol Res 2019 Jan 22. Epub 2019 Jan 22.

Department of Obstetrics and Gynecology, Bursa Yuksek Ihtisas Research and Training Hospital, Bursa, Turkey.

Aim: Subclinical hypothyroidism is thought to be associated with adverse pregnancy outcomes but the data is conflicting and generally depends on antibody positivity and treatment. We evaluated the pregnancy outcomes in Turkish population with untreated, antibody negative subclinical hypothyroidism for the first time.

Methods: We searched for 30 015 patients between January 2016 and May 2017 retrospectively. Read More

Obstet Gynecol Sci 2019 Jan 11;62(1):65-68. Epub 2018 Dec 11.

Department of Obstetrics and Gynecology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea.

Cervical varix is rare and can develop due to various conditions in pregnancy. Most cases of cervical varix during pregnancy are diagnosed in the second or third trimester and are usually associated with abnormal placental location, such as placenta previa or low-lying placenta. A 23-year-old woman with cervical varix bleeding visited our institution at 8 weeks of gestation. Read More

J Matern Fetal Neonatal Med 2019 Jan 22:1-6. Epub 2019 Jan 22.

a Department of Obstetrics and Gynecology, Etlik Zubeyde Hanim Womens' Health and Teaching Hospital , Health Science University , Ankara , Turkey.

Aim: To appraise the impact of previous birth type and the number of deliveries on placenta previa incidence and the extent of intrapartum massive hemorrhage.

Materials: Placenta previa complications among healthy singleton subsequent pregnancies following previous pregnancies without placenta previa history were classified according to their birth types and previous numbers of parity. Subgroups of subsequent pregnancies with massive hemorrhage and placental adhesion anomalies were compared. Read More

Int J Gynaecol Obstet 2019 Jan 22. Epub 2019 Jan 22.

Department of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, China.

Objective: To investigate the effect of balloon occlusion of internal iliac arteries during cesarean hysterectomy in women with placenta previa accreta.

Methods: Retrospective cohort study conducted using medical records of women with placenta previa and pathologically confirmed accreta taken from a single tertiary center in Chengdu, China, between January 1, 2012 and December 31, 2017. Baseline characteristics and pregnancy outcomes were compared between women with and without balloon occlusion of internal iliac arteries during cesarean delivery. Read More

Eur J Transl Myol 2018 Nov 2;28(4):7772. Epub 2018 Nov 2.

Shahid Akbarabadi Clinical Research Development Unit (ShACRDU), Iran University of Medical Sciences (IUMS), Tehran, Iran.

The aim of this study was to add ultrasonographic screening criteria for placenta accreta in patients with cesarean section history at 11-14 weeks of gestation in order to identify those with the high risk of placenta accreta. Consequently, using ultrasound follow-up and confirmation of diagnosis can reduce mortality and morbidity. Pregnant mothers who were referred for routine screening for ultrasonography at 11-14 weeks of gestation were enrolled in the study if they had a history of cesarean section. Read More

J Obstet Gynaecol Res 2019 Jan 17. Epub 2019 Jan 17.

Department of Obstetrics and Gynecology, Nippon Medical School Hospital, Tokyo, Japan.

Aim: This study aimed to assess whether hysteroscopic metroplasty using the incision method for septate uterus is a risk factor for adverse obstetric outcomes during pregnancy or delivery.

Methods: This retrospective, single-center cohort study of obstetric complications included 41 patients with recurrent pregnancy loss or unexplained infertility who underwent hysteroscopic metroplasty using the incision method for septate uterus. As controls, we recruited 1139 women who delivered at our hospital during the same period. Read More

N Engl J Med 2019 Jan;380(3):274

Osaka University, Osaka, Japan

BMC Pregnancy Childbirth 2019 Jan 15;19(1):30. Epub 2019 Jan 15.

The Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

Background: Severe obstetric hemorrhage caused by placenta accreta results in significant maternal morbidity and mortality. As a new technology, abdominal aortic balloon occlusion (AABO) is becoming an important treatment for patients with placenta accreta. To evaluate the safety and efficacy of AABO, we conducted a systematic review and meta-analysis of previous studies. Read More

Taiwan J Obstet Gynecol 2019 Jan;58(1):159-163

Department of Obstetrics and Gynecology, National Defense Medical College, Tokorozawa 359-8513, Japan.

Objective: Recently, Bakri balloon (BBT) was effective for women with placenta previa to reduce hemorrhage. However, about 10% of women needed to receive an invasive strategy. Thus, the identification of risk factors and the development of additional measurements for BBT failure was needed. Read More

Gynecol Obstet Invest 2019 Jan 9:1-7. Epub 2019 Jan 9.

Background: We aimed to compare the hemostatic effect and perioperative outcomes between internal iliac artery (IIA) and abdominal aorta (AA) balloon occlusions in pernicious placenta previa patients complicated with placenta accrete and underwent cesarean delivery.

Methods: One hundred and twenty-three pernicious placenta previa patients complicated with placenta accrete were retrospectively reviewed. Patients who received IIA or AA occlusions were subsequently divided into the IIA group (n = 71) and AA group (n = 52). Read More

Inflamm Bowel Dis 2019 Jan 8. Epub 2019 Jan 8.

Center for Clinical Epidemiology, Odense University Hospital and Research Unit of Clinical Epidemiology, Odense Denmark.

For decades, the research on reproductive consequences in women with inflammatory bowel disease (IBD) has focused on short-term outcomes, including adverse pregnancy outcomes (eg, abruptio placenta, placenta previa, preeclampsia/eclampsia) and adverse birth outcomes (eg, small for gestational age, preterm birth, and congenital malformations). The long-term health outcomes of the children of parents with IBD have been studied to a much lesser extent, and there is a critical research gap in understanding the influence of parental IBD on long-term outcomes. In this review, we propose the reasons for this lack of evidence and highlight the weakest areas of the research on the impact of parental IBD on offspring health. Read More

Abdom Radiol (NY) 2019 Jan 1. Epub 2019 Jan 1.

Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, Chieti, Italy.

Purpose: To investigate the diagnostic accuracy of MRI for placenta accreta spectrum (PAS) and clinical outcome prediction in women with placenta previa, using a novel MRI-based predictive model.

Methods: Thirty-eight placental MRI exams performed on a 1.5T scanner were retrospectively reviewed by two radiologists in consensus. Read More

Syst Rev 2018 Dec 27;7(1):249. Epub 2018 Dec 27.

Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.

Background: Placenta praevia refers to a placenta located in the lower segment of the uterus. This abnormal location predisposes the placenta to abnormal bleeding with an increased risk of premature labour. The merits of tocolytic drugs (tocolysis) to calm uterine contractions and prolong pregnancy in women with placenta praevia are uncertain. Read More

Harefuah 2018 Dec;157(12):783-786

Department of Gynecology and Obstetrics, Rambam Health Care Campus, affiliated with Technion-Israel Institute of Technology, Haifa, Israel.

Introduction: Smoking during pregnancy is a public health problem because of the many adverse effects associated with it. These include intrauterine growth restriction, placenta previa, abruptio placentae, decreased maternal thyroid function, preterm premature rupture of membranes, low birth weight, perinatal mortality, and ectopic pregnancy. An estimated 5-8% of pre-term deliveries, 13-19% of term deliveries of infants with low birth weight, 23-34% cases of sudden infant death syndrome (SIDS), and 5-7% of preterm-related infant deaths can be attributed to prenatal maternal smoking. Read More

J Magn Reson Imaging 2018 Dec 21. Epub 2018 Dec 21.

Department of Radiology, School of Medicine, National and Kapodistrian University of Athens, Aretaieion Hospital, Athens, Greece.

Background: Placenta accreta spectrum (PAS) disorders may be associated with significant mortality and morbidity for both mother and fetus.

Purpose/hypothesis: To identify MRI risk factors for poor peripartum outcome in gravid patients at risk for PAS.

Study Type: Prospective. Read More

Semin Perinatol 2018 Nov 15. Epub 2018 Nov 15.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, United States.

The term "morbidly adherent placenta" has recently been introduced to describe the spectrum of disorders including placenta accreta, increta and percreta. Due to excessive invasion of the placenta into the uterus there is associated significant maternal morbidity and mortality. Most significant risk factors for morbidly adherent placenta include history of prior cesarean delivery as well as placenta previa in the current pregnancy. Read More

Obstet Gynecol 2019 Jan;133(1):e73-e77

The incidence of cesarean delivery on maternal request and its contribution to the overall increase in the cesarean delivery rate are not well known, but it is estimated that 2.5% of all births in the United States are cesarean delivery on maternal request. Cesarean delivery on maternal request is not a well-recognized clinical entity. Read More

Obstet Gynecol 2019 Jan;133(1):226-227

The incidence of cesarean delivery on maternal request and its contribution to the overall increase in the cesarean delivery rate are not well known, but it is estimated that 2.5% of all births in the United States are cesarean delivery on maternal request. Cesarean delivery on maternal request is not a well-recognized clinical entity. Read More

Int J Gynaecol Obstet 2019 Mar 16;144(3):252-259. Epub 2019 Jan 16.

Faculty of Health, University of Technology Sydney, Sydney, NSW, Australia.

Objectives: To define current obstetric opinion and clinical practice regarding the prenatal diagnosis of vasa previa in Australia and New Zealand.

Methods: A population-based cross-sectional survey of Fellows of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists was conducted from April to May, 2016. Descriptive analysis was used to define factors influencing opinion and practice regarding definition of vasa previa, attributable risk factors, and the value of screening. Read More

Taiwan J Obstet Gynecol 2018 Dec;57(6):910

Department of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Saitama, 359-8513, Japan.

Taiwan J Obstet Gynecol 2018 Dec;57(6):909

Perinatal and Maternal Center of Saitama Medical Center, Jichi Medical University, Saitama, Japan.

Taiwan J Obstet Gynecol 2018 Dec;57(6):814-818

Clinical Medical College, Yangzhou University, Yangzho, 225001, Jiangsu, China; Department of Gynecology and Obstetrics, Northern Jiangsu People's Hospital, Yangzhou, 225001, Jiangsu, China. Electronic address:

Objective: The aim is to examine risk factors and neonatal outcomes of preterm birth and to provide basis in preventing preterm birth.

Materials And Methods: we carried out our study on 1328 term controls and 1328 preterm birth cases. By using multivariable logistic regression procedures we estimated odds ratio (OR) of potential preterm birth risk factors. Read More

Medicine (Baltimore) 2018 Dec;97(49):e13375

Department of Obstetrics, Jinan Maternity and Child Care Hospital, Jinan, China.

This study is to investigate the role of cervical morphology evaluated by magnetic resonance imaging (MRI) in predicting invasive placenta previa (IPP).Totally 105 cases of pregnant women underwent prenatal placental MRI at 32 to 36 weeks of gestation for suspected IPP were included in this study. Cervical morphology (cervical length and placental protrusion) was evaluated independently by 2 radiologists. Read More

Arch Gynecol Obstet 2019 Feb 12;299(2):593-594. Epub 2018 Dec 12.

Department of Obstetrics and Gynecology, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.

Zhonghua Yi Xue Za Zhi 2018 Dec;98(45):3692-3696

Department of Radiology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China.

To investigate the diagnostic value of MRI for placenta previa complicated with placenta accreta or not. A total of 220 placenta previa patients were diagnosed by prenatal ultrasound and MRI in The Second Affiliated Hospital of Wenzhou Medical University from May 2014 to May 2017.The MRI images of 220 placenta previa patients suspicious of placenta previa were interpreted by two radiologists who majored on gynecological radiology. Read More

J Matern Fetal Neonatal Med 2018 Dec 5:1-161. Epub 2018 Dec 5.

a Department of Obstetrics and Gynecology , Jichi Medical University , Shimotsuke , Tochigi , Japan.

Objectives: To clarify perinatal outcomes of patients with placenta previa (PP) with the placenta mainly positioned in the lateral uterine wall (lateral PP), thereby clinically characterizing this condition.

Study Design: The retrospective cohort study was performed involving patients with lateral PP between January 2006 and December 2016. The placental position was determined and classified by magnetic resonance imaging. Read More

Am J Perinatol 2018 Nov 30. Epub 2018 Nov 30.

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut.

Objective:  Placenta accreta is a feared pathology, in part, because prenatal diagnosis is imperfect. It is not known whether clinical risk factors or sonographic features equally predict the entire graded pathological spectrum of placental overinvasion disease nor whether clinical outcomes differ along the spectrum.

Study Design:  We conducted a mixed methods retrospective study of a cohort of women screened sonographically for placenta accreta, cross-referenced against cases identified by pathological diagnosis ( = 416). Read More

J Matern Fetal Neonatal Med 2018 Nov 28:1-151. Epub 2018 Nov 28.

a Department of Obstetrics and Gynecology , Hadassah , Hebrew University Medical Center , Jerusalem , Israel.

Objective: While surgical management is the treatment of choice for abnormally invasive placenta, the role of supracervical hysterectomy in this setting is not well established. We aimed to compare supracervical versus total cesarean hysterectomy as a surgical option for abnormally invasive placenta.

Methods: We carried out a 8-year retrospective case-control study. Read More

J Matern Fetal Neonatal Med 2018 Nov 28:1-71. Epub 2018 Nov 28.

a Department of Obstetrics and Gynecology , Gaziantep University , School of Medicine , Gaziantep , Turkey.

Purpose: This study described a new technique to minimize the bleeding resulted from aberrant engorged vessels and unintended bladder injury in cases with abnormally invaded placenta adjacent to posterior bladder wall at cesarean hysterectomy.

Methods: After filling the bladder with 300 ml saline aberrant engorged vessels were identified and skeletonized between lower uterine segment and bladder with blunt dissection by index finger down to the distal end point of cervix.

Results: This technique has beneficial effect on preventing bladder injury and reduces bleeding resulting from the aberrant vessels and the communicating vessels that were based around the vesicouterine fold and the cervico-vesical interface (in the lower part of the cervix); respectively. Read More

J Ultrasound Med 2018 Nov 27. Epub 2018 Nov 27.

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Objectives: The influence of placental morphologic characteristics on pregnancy outcomes is poorly understood. Our objective was to evaluate the relationship of the distance of the placental cord insertion from the placental edge (PCI-D) with associated placental characteristics as well as birth outcomes.

Methods: We performed a retrospective cohort study of nulliparous women with singleton gestations undergoing obstetric ultrasound examinations between 14 and 23 weeks' gestation with a cervical length of greater than 3. Read More

Transfus Apher Sci 2018 Dec 16;57(6):793-796. Epub 2018 Nov 16.

Department of Perinatology, Division of Obstetrics and Gynaecology, University Medical Centre Ljubljana, Zaloška cesta 2, 1000, Ljubljana, Slovenia. Electronic address:

Objective: The aim of this study was to evaluate the usability of preoperative autologous blood donation (PAD) in pregnant women with placenta previa.

Study Design: We retrospectively reviewed 142 pregnancies with placenta previa from completed 32 weeks of gestation who underwent a caesarean delivery in University clinical centre Ljubljana, over a five-year period.

Result: Although more than two thirds of pregnant women met the criteria for PAD, it was justified for approximately 13. Read More

J Int Med Res 2019 Jan 22;47(1):206-214. Epub 2018 Nov 22.

Department of Obstetrics, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fujian, Fuzhou, China.

Objectives: To investigate the expression of β-catenin in chorionic villi, and to explore its roles in placenta accreta and placenta previa.

Methods: We compared β-catenin expression in the control group, placenta accreta group (lesion area and normal zones), and placenta previa group (placental central and placental edge zones) by immunohistochemistry, Western blotting, and RT-PCR techniques.

Results: Compared with the normal group, the placenta accreta group had a longer length of stay, greater bleeding volume, and lower newborn birth weight. Read More

Gynecol Obstet Invest 2018 Nov 16:1-6. Epub 2018 Nov 16.

Department of Obstetrics and Gynecology, Obstetrical-Gynecological Ultrasound Unit, "Sant'Anna Hospital", Turin, Italy.

Background/aims: Abnormally invasive placenta (AIP) includes placenta accreta, increta, and percreta and represents major complications of pregnancy. This study was designed to assess the role of ultrasonography in the identification of AIP among pregnant women with antepartum diagnosis of placenta previa.

Methods: A cross-sectional study was performed between May 2015 and April 2016 in 11 centers, including 242 women with antepartum diagnosis of placenta previa. Read More

AJP Rep 2018 Oct 14;8(4):e325-e327. Epub 2018 Nov 14.

Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts.

 Morbidly adherent placenta represents a surgical challenge and source of maternal morbidity and mortality. We report the use of a fibrin sealant patch to address hemorrhage associated with a morbidly adherent placenta during cesarean delivery.  A patient underwent repeat cesarean delivery with complete anterior placenta previa and anticipated morbidly adherent placenta. Read More

Medicine (Baltimore) 2018 Nov;97(46):e13253

The rising tendency of cesarean sections will lead invariably to more complications such as placenta praevia. The aim of our study was to evaluate the utility of parallel vertical compression suture to preserve uterus in cases of placenta praevia, and to propose a rational approach of these problematic cases, according to their grade of myometrial invasion.We prospectively included 95 consecutive cases diagnosed with placenta praevia (group1 [Gr1]) where we used parallel compression suture and compared to retrospectively analyzed 100 consecutive cases managed without using this technique (group 2 [Gr2]). Read More