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Gynecol Endocrinol 2020 Jun 3:1-4. Epub 2020 Jun 3.

Department of Medicine, University Hospital of Pisa, Pisa, Italy.

Diet and physical activity are cornerstones in prevention and treatment of Gestational Diabetes (GDM) though some caution may be required under specific circumstances. The aims of this study were to evaluate activity habits during pregnancy and contraindications to physical activity in women at risk for GDM 536 pregnant women (age 35 ± 5 years; gestation week 25 ± 4; pre-pregnancy BMI 24.6 ± 12. Read More

Obstet Gynecol Sci 2020 May 26;63(3):231-238. Epub 2020 Mar 26.

Department of Obstetrics and Gynecology, Gachon University Gil Medical Center, Incheon, Korea.

Objective: We aimed to evaluate the effectiveness of cervical pessary for extending twin pregnancy in women with a short cervix.

Methods: Between January 2014 and March 2019, the use of a cervical pessary for twin pregnancy in women with a cervical length of ≤15 mm was investigated between 16 and 28 weeks of gestation. We included women with a shortened cervix after a cerclage procedure and visible fetal membranes and cervical dilatation. Read More

BMC Anesthesiol 2020 May 30;20(1):133. Epub 2020 May 30.

Department of Stomatology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.

Background: This retrospective study aimed to compare the clinical outcomes of parturients with placenta previa (PP) and placenta accreta (PA) according to their severity, when they were managed with intraoperative abdominal aortic balloon occlusion (IAABO) during cesarean section.

Methods: We retrospectively examined 57 cases of PP and suspicion for PA in which IAABO was performed during cesarean section between April 2014 and June 2016. Based on preoperative examination and clinical risk factors, patients were divided into the low suspicion PA group and the high suspicion PA group. Read More

Zhonghua Fu Chan Ke Za Zhi 2020 May;55(5):317-321

Department of Obstetrics and Gyneclogy, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou Critical Care Center of Pregnant Women, Guangzhou 510150, China.

To investigate the appropriate method of labor induction in the second trimester for complete placenta previa patients. The labor induction outcomes of 85 cases with complete placenta previa in the second trimester were retrospectively analyzed. Twenty patients in group A were treated with cesarean section, 30 patients in group B were treated with ethacridine and mifepristone combined with uterine artery embolization (UAE), and 35 patients in group C were induced by using ethacridine and mifepristone. Read More

Placenta 2020 Apr 26;95:44-52. Epub 2020 Apr 26.

Makassed General Hospital, Beirut, Lebanon.

Placenta accreta spectrum (PAS) is a major obstetrical problem whose incidence is rising. Current guidelines recommend screening of all women with placenta previa and risk factors for PAS between 20 and 24 weeks. Risk factors, diagnosis, and management of previa PAS are well established, but an apparently normal location of the placenta does not exclude PAS. Read More

Am J Perinatol 2020 May 23. Epub 2020 May 23.

Women and Children's Health Research Unit, Gertner Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel.

Objective:  We aimed to determine the independent effect of maternal antepartum hemorrhage (APH) on mortality and major neonatal morbidities among very low birth weight (VLBW), very preterm infants.

Study Design:  A population-based cohort study of VLBW singleton infants born at 24 to 31 weeks of gestation between 1995 and 2016 was performed. Infants born with the following pregnancy associated complications were excluded: maternal hypertensive disorders, prolonged rupture of membranes, amnionitis, maternal diabetes, and small for gestational age. Read More

J Matern Fetal Neonatal Med 2020 May 19:1-7. Epub 2020 May 19.

Department of Obstetrics and Gynecology, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey.

Cesarean delivery (CD) is one of the most common operations worldwide. Vaginal birth after cesarean (VBAC) could be a solution to decrease increased CD rates. On the other hand, risks of VBAC on maternal and neonatal outcomes drifts physicians and patients to a scheduled CD. Read More

Front Bioeng Biotechnol 2020 30;8:343. Epub 2020 Apr 30.

Department of Medical Imaging and Interventional Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.

In order to predict the amount of bleeding in the cesarean section of the patients with Pernicious Placenta Previa (PPP), this study proposed an automatic blood loss prediction method based on Magnetic Resonance Imaging (MRI) uterus image. Firstly, the DeepLab-V3 + network was used to segment the original MRI abdominal image to obtain the uterine region image. Then, the uterine region image and the corresponding blood loss data were trained by Visual Geometry Group Network-16 (VGGNet-16) network. Read More

Clin Epidemiol 2020 29;12:405-414. Epub 2020 Apr 29.

Department of Obstetrics and Gynaecology, Women's Hospital, Zhejiang University School of Medicine, People's Republic of China.

Background And Aim: Maternal near-miss (MNM) surveillance has been developed to identify severe complications in pregnancy since 2011 in China. However, very little is known about MNM in China. This study aims to explore the prevalence of MNM, the risk factors, and perinatal outcomes using the WHO near-miss approach in a developed Chinese province. Read More

Transl Androl Urol 2020 Apr;9(2):258-266

MR Scientific Marketing Specialist, Siemens Healthineer, Shanghai 201318, China.

Background: The incidence of placenta accreta spectrum (PAS) disorders has increased rapidly in recent years and is associated with several maternal and neonatal complications. Intravoxel incoherent motion (IVIM) imaging is a method which can assess placental perfusion quantitatively. Therefore, the first aim of this study was to investigate whether patients with adverse maternal and neonatal outcomes of PAS disorders differed in the parameters from IVIM. Read More

BJOG 2020 May 16. Epub 2020 May 16.

Institut national de santé publique du Québec, Montreal, Quebec, Canada.

Objective: To investigate the association between obstetric hemorrhage and cardiovascular disease up to three decades after pregnancy.

Design: Population-based cohort study SETTING AND POPULATION: All women who delivered between 1989 and 2016 in Quebec, Canada.

Methods: Using hospital admissions data, 1,224,975 women were followed from their first delivery until March 2018. Read More

Anesthesiol Res Pract 2020 30;2020:1358258. Epub 2020 Apr 30.

Department of Anesthesiology and Reanimation, Kahramanmaras Sütcü İmam University Faculty of Medicine, Kahramanmaras, Turkey.

Background: In this study, patients who underwent cesarean section and had placenta previa and placenta accreta were examined and compared in terms of haemorrhagic indicators and perioperative anesthetic management.

Methods: A retrospective study was conducted in a university hospital in Kahramanmaras, Turkey. It included 95 pregnant women who had placental anomaly and underwent cesarean section between December 15, 2014, and February 15, 2016. Read More

BMC Health Serv Res 2020 May 13;20(1):421. Epub 2020 May 13.

Department of Anesthesiology, International University of Health and Welfare, Mita Hospital, Tokyo, Japan.

Background: The indications for general anesthesia (GA) in obstetric settings, which are determined in consideration of maternal and fetal outcome, could be affected by local patterns of clinical practice grounded in unique situations and circumstances that vary among medical institutions. Although the use of GA for cesarean delivery has become less common with more frequent adoption of neuraxial anesthesia, GA was previously chosen for pregnancy with placenta previa at our institution in case of unexpected massive hemorrhage. However, the situation has been gradually changing since formation of a team dedicated to obstetric anesthesia practice. Read More

J Pregnancy 2020 6;2020:5630296. Epub 2020 Jan 6.

Department of Obstetrics and Gynecology, Addis Ababa University, Ethiopia.

Background: Placenta praevia is a disorder that happens during pregnancy when the placenta is abnormally placed in the lower uterine segment, which at times covers the cervix. The incidence of placenta praevia is 3-5 per 1000 pregnancies worldwide and is still rising because of increasing caesarean section rates.

Objective: To assess and identify the risk factors and maternal and neonatal complications associated with placenta praevia. Read More

Saudi J Kidney Dis Transpl 2020 Mar-Apr;31(2):368-379

Department of Nephrology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

Pregnancy-related acute kidney injury (PRAKI) and urological complications can significantly increase the maternal morbidity and mortality, and morbidly adherent placenta (MAP) has been found to increase the risk of both. This is a four-year prospective study, conducted on patients with MAP. Baseline parameters (demographic/antenatal/perinatal), operative details (obstetric/urological/hemostatic), peri-operative complications (AKI/urological), and maternal/fetal outcomes were studied till six weeks after delivery. Read More

Eur J Obstet Gynecol Reprod Biol 2020 Apr 21;250:54-60. Epub 2020 Apr 21.

Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom; Department of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, United Kingdom; Department of Development and Regeneration, KU Leuven, Belgium. Electronic address:

Introduction: The antenatal diagnosis of placenta accreta spectrum (PAS) is in large part subjective and based on expert interpretation. The aim of this study was to externally evaluate a recently developed staging system based on specific and defined prenatal ultrasound (US) features in a cohort of women at risk of PAS undergoing specialist prenatal US, in particular relating to surgical morbidity at delivery.

Materials And Methods: Database study of cases with confirmed placenta previa. Read More

J Ultrasound Med 2020 May 6. Epub 2020 May 6.

Departments of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Parkland Health and Hospital System, Dallas, Texas, USA.

Objectives: To prospectively evaluate low implantation of the gestational sac and other first-trimester ultrasound (US) parameters for prediction of placenta accreta spectrum (PAS).

Methods: Women with a diagnosis of low implantation on clinically indicated first-trimester US underwent a transvaginal US examination at 10 to 13 weeks' gestation to assess the trophoblast location, anechoic areas, bridging vessels, and smallest myometrial thickness (SMT). The placental location was evaluated in the second trimester, and serial US examinations were performed in cases of low placentation. Read More

Aust N Z J Obstet Gynaecol 2020 May 5. Epub 2020 May 5.

Westmead Institute for Maternal and Foetal Medicine, Westmead Hospital, Sydney, Australia.

Background: Placenta praevia is characterised by an inferior placental margin that overlies or falls within 20 mm of the endocervical os. It remains a common cause of antepartum haemorrhage and is associated with adverse maternal and neonatal outcomes.

Aims: We aimed to determine the association between antepartum and postpartum haemorrhage and adverse outcomes in cases of placenta praevia. Read More

Am J Obstet Gynecol 2020 Apr 30. Epub 2020 Apr 30.

Depatment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas. Electronic address:

Background: Placenta accreta spectrum (PAS) is well known in its association with catastrophic maternal outcomes. However, the pathophysiology rendering PAS is not well-defined. There has been emerging data that in vitro fertilization (IVF) may be a risk factor for placenta accreta. Read More

Gynecol Obstet Fertil Senol 2020 Apr 30. Epub 2020 Apr 30.

Service de gynécologie obstétrique, centre hospitalier universitaire de Nantes, 44093 Nantes cedex 1, France.

Objective: To synthesize knowledge on the consequences of active smoking in pregnancy.

Methods: The MedLine database, the Cochrane Library and French and foreign guidelines from 1999 to 2019 have been consulted.

Results: Active maternal smoking is associated with an increased risk of first trimester complications such as early miscarriage and ectopic pregnancy with a dose-effect relationship between smoking and those risks. Read More

Am J Obstet Gynecol 2020 Apr 28. Epub 2020 Apr 28.

The Society for Maternal-Fetal Medicine: Publications Committee, 409 12th St, SW, Washington, DC 20024.

Despite current recommendations against its use, activity restriction remains a common intervention used to prevent preterm birth in multiple clinical settings. Hypertensive disorders of pregnancy, preterm premature rupture of membranes (PPROM), multiple gestations, vaginal bleeding, short cervical length, placenta previa, and fetal growth restriction (FGR) are also common reasons for antepartum hospital admission and frequently lead to a recommendation for activity restriction. However, numerous reports have shown that activity restriction does not prevent adverse obstetrical outcomes but does confer significant physical and psychosocial risks. Read More

BMJ Open 2020 Apr 28;10(4):e033675. Epub 2020 Apr 28.

Department of Health and Psychosocial Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan

Objectives: This study aimed to identify intrauterine growth differences according to infertility treatment compared with spontaneous conception and to describe intrauterine growth trajectories.

Design: Retrospective cohort study.

Setting: A single primary and tertiary medical centre in Japan. Read More

Obstet Gynecol 2020 May;135(5):e221-e229

Pregnant women should be advised of the significant perinatal risks associated with tobacco use, including orofacial clefts, fetal growth restriction, placenta previa, abruptio placentae, preterm prelabor rupture of membranes, low birth weight, increased perinatal mortality, ectopic pregnancy, and decreased maternal thyroid function. Children born to women who smoke during pregnancy are at an increased risk of respiratory infections, asthma, infantile colic, bone fractures, and childhood obesity. Pregnancy influences many women to stop smoking, and approximately 54% of women who smoke before pregnancy quit smoking directly before or during pregnancy. Read More

Obstet Gynecol 2020 May;135(5):1244-1246

Pregnant women should be advised of the significant perinatal risks associated with tobacco use, including orofacial clefts, fetal growth restriction, placenta previa, abruptio placentae, preterm prelabor rupture of membranes, low birth weight, increased perinatal mortality, ectopic pregnancy, and decreased maternal thyroid function. Children born to women who smoke during pregnancy are at an increased risk of respiratory infections, asthma, infantile colic, bone fractures, and childhood obesity. Pregnancy influences many women to stop smoking, and approximately 54% of women who smoke before pregnancy quit smoking directly before or during pregnancy. Read More

Rev Bras Ginecol Obstet 2020 Apr 24;42(4):200-210. Epub 2020 Apr 24.

Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Objective:  The present study is a systematic review of the literature to assess whether the presence of endometriosis determines or contributes to adverse obstetric outcomes.

Data Sources:  The present work was carried out at the Hospital Israelita Albert Einstein, São Paulo, state of São Paulo, Brazil, in accordance to the PRISMA methodology for systematic reviews. A review of the literature was performed using PubMed, Web of Science and Scopus databases. Read More

Fertil Steril 2020 May 20;113(5):996-1004. Epub 2020 Apr 20.

Endometriosis Center, Clinique Tivoli-Ducos, Bordeaux, France; Department of Gynecology and Obstetrics, University Hospital Aarhus, Aarhus, Denmark. Electronic address:

Objective: To assess the relationship between history of surgery for endometriosis and adverse obstetrical outcomes.

Design: Retrospective study using prospectively recorded data.

Setting: Referral center. Read More

Front Med (Lausanne) 2020 8;7:104. Epub 2020 Apr 8.

Center for Reproductive Medicine, Shandong University, Jinan, China.

This study aims to investigate whether obstetric complications and perinatal outcomes after frozen embryo transfer (FET) in the programming cycles differ from that in the natural cycles. We conducted a retrospective cohort study collecting a total of 14,373 singletons born after frozen embryo transfer at the Center for Reproductive Medicine Affiliated to Shandong University from September 2013 to September 2018. The women were divided into two groups according to the regimens for endometrium preparation: either natural cycles ( = 10,211) or programming cycles ( = 4,162). Read More

J Matern Fetal Neonatal Med 2020 Apr 21:1-7. Epub 2020 Apr 21.

Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.

There is limited information on neonatal outcomes in complicated pregnancies with abnormal placentation. The aim of this study was to assess the neonatal outcomes of abnormal placentation. In this case-control study, known cases of abnormal placentation between the years 2010 and 2017 were extracted. Read More

J Pak Med Assoc 2020 Apr;70(4):577-582

Sakarya University, Turkey.

Objective: To find prevalence of preterm birth in Pakistan and to explore its related risk factors.

Methods: This analytical cross-sectional study was conducted from October 1, 2016, to September 30, 2017, at Hajvery University, Lahore, Pakistan, and data was collected from Obstetrics and Gynaecology departments of various hospitals in four provinces of the country. To find risk factors of preterm birth, data was divided into two groups: Group-1 consisted cases with preterm birth defined as gestational age <37 weeks on ultrasonography; and Group-2 consisted controls with full-term birth defined as gestational age 37-41 weeks. Read More

BMC Pregnancy Childbirth 2020 Apr 15;20(1):222. Epub 2020 Apr 15.

Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, 566, Nonhyeon-ro, Gangnam-gu, Seoul, 135-081, Republic of Korea.

Background: Twin pregnancies with uterine fibroid(s) (UFs) may not be at increased risk for obstetric complications compared to those without UFs. However, there was no reported comparison study with obstetric outcomes and complications of twin pregnancy after myomectomy. We aimed to compare the pregnancy outcomes in twin pregnancies with or without uterine fibroid(s), and also compared in patients with previous myomectomy history in Korean women. Read More

J Matern Fetal Neonatal Med 2020 Apr 15:1-7. Epub 2020 Apr 15.

Reroductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

The aim of this study was to evaluate the impact of male infertility or intracytoplasmic sperm injection (ICSI) technique on perinatal outcomes. A retrospective cohort study included patients with singleton live births after fresh-cycle embryo transfer that occurred between 1 January 2016 and 31 May 2018. The patients were divided into four groups: (1) IVF treatment without male infertility; (2) ICSI treatment without male infertility; (3) ICSI treatment with male infertility; and (4) IVF treatment with male infertility. Read More

Medicina (Kaunas) 2020 Apr 13;56(4). Epub 2020 Apr 13.

Department of Obstetrics and Gynecology, New York Health and Hospitals/Lincoln, Bronx, NY 10451, USA.

: Risk factors for neonatal/maternal morbidity and mortality in placental abruption have been incompletely studied in the current literature. Most of the research overlooked the African American population as mostly Caucasian populations are selected. We aimed to find which risk factor influence the neonatal and maternal outcome in cases of placental abruption occurring in African American pregnant women in an inner-city urban setting. Read More

Hum Reprod 2020 Apr;35(4):805-815

Fertility Clinic, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Study Question: Are obstetric and perinatal outcomes in pregnancies after fresh blastocyst transfer (BT) comparable with those born after fresh cleavage stage transfer (CT) and spontaneous conception (SC)?

Summary Answer: Fresh BT is associated with a higher risk of placental and perinatal complications.

What Is Known Already: BT optimizes the selection of top-quality embryos and increases pregnancy and live birth rates per transfer compared to CT. However, concerns have been raised as extended culture duration may increase obstetric complications and impair perinatal outcomes. Read More

BMC Pregnancy Childbirth 2020 Apr 15;20(1):212. Epub 2020 Apr 15.

Department of Obstetrics and Gynecology, Guangzhou Medical Centre for Critical Pregnant Women, Key Laboratory for Major Obstetric Diseases of Guangdong Province, Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, 510150, China.

Background: To determine the effects of previous placenta previa on the maternal and neonatal outcomes of the next pregnancy.

Methods: This 10-year retrospective cohort study was conducted in the Department of Obstetrics and Gynecology, Third Affiliated Hospital of Guangzhou Medical University, between January 2009 and 2018. We retrospectively analyzed the effects of a previous singleton pregnancy in women with and without placenta previa on the outcomes of the subsequent pregnancy. Read More

Obstet Gynecol 2020 May;135(5):1112-1119

Departments of Obstetrics and Gynecology, Ultrasound, Radiology, and Pathology and the Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, West China Second University Hospital of Sichuan University, Chengdu, China.

Objective: To investigate the effect of intraoperative balloon occlusion of the internal iliac arteries in women with placenta previa and antenatally diagnosed placenta accreta.

Methods: In this single-center, randomized controlled trial, women with placenta previa and antenatally suspected placenta accreta were randomly assigned to either the balloon occlusion group or to the control group. The perioperative management approach was similar for both groups, other than preoperative balloon catheter placement and intraoperative occlusion of bilateral internal iliac arteries. Read More

J Obstet Gynaecol Res 2020 Jun 12;46(6):883-889. Epub 2020 Apr 12.

Department of Ultrasound, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.

Aim: The incidence of placenta previa before the third trimester is high. But many cases resolve as pregnancy progresses. Our study was to evaluate the efficacy of uterine artery Doppler velocimetry at mid-term gestation for predicting placenta previa resolution in third trimester. Read More

J Obstet Gynaecol Res 2020 Apr 12. Epub 2020 Apr 12.

Department of Obstetrics and Gynecology, St. Marianna University School of Medicine, Kanagawa, Japan.

Aim: This study aimed to clarify ultrasound screening and management for vasa previa (VP) in perinatal centers and primary facilities in Japan.

Methods: A questionnaire survey about antepartum ultrasound screening and management for VP was delivered in 2018. Questions were sent by email or post to perinatal centers and randomly selected primary hospitals or clinics throughout Japan. Read More

Patient Saf Surg 2020 31;14. Epub 2020 Mar 31.

2Department of anesthesia, Univesity of Gondar, Gondar, Ethiopia.

Background: Spinal anesthesia-induced maternal hypotension is the most frequent complication associated with maternal morbidity and mortality during Cesarean section. The aim of this study was to compare the incidence and magnitude of hemodynamic changes in preeclamptic and non-preeclamptic parturients undergone Cesarean section under spinal anesthesia.

Method: A prospective cohort study was conducted from 01 February to 28 May 2019 in preeclamptic and non-preeclamptic parturients. Read More

Am J Perinatol 2020 Mar 27. Epub 2020 Mar 27.

Department of Laboratory Medicine, Taizhou Women's and Children's Hospital, Zhejiang Province, China.

Objective:  In this study, our objective was to explore the relevant influencing factors of neonatal hypoxic-ischemic encephalopathy (HIE) in Southern China and provide scientific basis for improving the quality of life for neonates.

Study Design:  A retrospective analysis of 306 cases with HIE neonates who were admitted during April 2015 to October 2017 was conducted. A total of 306 non-HIE patients admitted to the same hospital during the same period were also included as controls. Read More

J Int Med Res 2020 03;48(3):300060520910049

Department of Obstetrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.

AJR Am J Roentgenol 2020 Jun 24;214(6):1417-1423. Epub 2020 Mar 24.

Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390.

The purpose of this study is to determine whether MRI parameters of placenta accreta spectrum correlate with pathologic and surgical outcomes in high-risk pregnancies. This retrospective study evaluated second- and third-trimester pregnancies assessed by MRI from 2007 to the present. Women were included in the study if placental invasion was suspected on the basis of a clinical history of cesarean delivery, ultrasound findings, or both. Read More

J Obstet Gynaecol Res 2020 Jun 23;46(6):876-882. Epub 2020 Mar 23.

Department of Obstetrics and Gynecology, Gachon University Gil Medical Center, Incheon, Korea.

Aim: We evaluated the effectiveness of intraoperative wireless ultrasonography in determining the location of uterine incision during cesarean delivery in patients with placenta previa who have sonographic adherence findings in order to assess intraoperative blood loss and maternal morbidity.

Methods: A prospective study using wireless sonography, including 15 patients with previa, was conducted among women with singleton pregnancies who delivered by cesarean section between August 1, 2017, and August 30, 2019. Retrospective study for the control group included 32 patients with placenta previa who underwent cesarean section between January 1, 2016, and July 31, 2017, without wireless sonography. Read More

Enferm Clin 2020 Mar;30 Suppl 2:524-527

Department of Pathology Anatomy, Hasanuddin University, Indonesia.

Objective: This study aimed to determine the relationship of parity, exposure to cigarette smoke, and the presence of bacteria Stenotrophomonas maltophilia with the incidence of preterm labor.

Method: It was a cross-sectional study, the sampling was carried out using a purposive sampling technique for maternity women at the Siti Fatimah Makassar Mother and Child Hospital, Siti Khadija I Makassar Mother and Child Hospital, and Makassar City Regional General Hospital in June until August 2019. The study sample consisted of 50 post-partum mothers and their placenta, consisting of 25 preterm mothers and 25 term mothers. Read More

Ann Transl Med 2020 Feb;8(4):51

Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha 410013, China.

Background: Intrauterine adhesion (IUA) is caused by adhesion of the uterine cavity due to the damage of endometrium. Hysteroscopic adhesiolysis (HA) is the main treatment. The objective of the study was to investigate the obstetrical outcome in the third trimester of women who previously underwent HA. Read More

Placenta 2020 02 23;91:37-42. Epub 2020 Jan 23.

Department of Obstetrics and Gynecology, Hackensack University Medical Center, Hackensack, NJ 07601, USA.

Introduction: Abnormally invasive placenta (AIP, aka placenta accreta spectrum; PAS) is an increasingly common pregnancy pathology, which, despite significant morbidity risk to the mother, is often undiagnosed prior to delivery. We tested several potential biomarkers in plasma from PAS mothers to determine whether any were sufficiently robust for a formal, diagnostic accuracy study.

Methods: We examined hyperglycosylated hCG (h-hCG), decorin and IL-8, based on biological plausibility and literature indications that they might be altered in PAS. Read More

BMC Pregnancy Childbirth 2020 Mar 14;20(1):161. Epub 2020 Mar 14.

Department of Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 JieFang Avenue, Wuhan, 430030, People's Republic of China.

Background: Adverse obstetric outcomes are correlated with altered circulating hormone levels at the time implantation by the trophectoderm. What' more, embryo freezing process may also have adverse effect on perinatal outcomes. This study aims to evaluate whether increasing interval time between a freeze-all cycle and a subsequent frozen-thawed single blastocyst transfer could have any effect on pregnancy and perinatal outcomes. Read More

Obstet Gynecol 2020 Apr;135(4):953-959

Maternal Fetal Medicine Section, Department of Obstetrics & Gynecology, and the Department of Obstetrics & Gynecology, University of Calgary, and EFW Radiology, Calgary, Alberta, Canada.

Objective: To evaluate the association between antenatal diagnosis of velamentous and marginal placental cord insertions with adverse perinatal outcomes of small-for-gestational-age (SGA) birth weight (less than the 5th percentile), caesarean birth, and perinatal mortality.

Methods: Using a diagnostic imaging database, we performed a cohort study of all consecutive singleton pregnancies (35,391), including 1,427 cases of marginal and 107 cases of velamentous cord insertion, delivered after 24 6/7 weeks of gestation between January 1, 2012, and December 31, 2015, at a single Canadian tertiary care center. Cases with placenta previa, vasa previa, no documented cord insertion, or fetal anomalies were excluded. Read More

SA J Radiol 2020 6;24(1):1817. Epub 2020 Feb 6.

Department of Diagnostic Radiology, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

An amniocele, or contained uterine rupture, is a phenomenon in which there is herniation of the amniotic sac through a uterine defect, secondary to various causes. It is associated with severe morbidity and mortality. This case presents the findings in a 36-year-old female at 29 weeks gestation who was initially managed as antepartum haemorrhage secondary to placenta previa, based on ultrasound. Read More

J Obstet Gynaecol Res 2020 May 9;46(5):699-706. Epub 2020 Mar 9.

Department of Obstetrics and Gynecology, University of Gaziantep, Gaziantep, Turkey.

Objective: To compare acoustic radiation force impulse (ARFI) elastography values and histopathological diagnoses (accreta, increta, percreta) in patients suspected of having abnormal placental invasion (API).

Materials And Methods: This prospective study included 54 patients in the third trimester with a history of caesarian section (CS) and API based on gray scale and Doppler ultrasonography (USG) and 35 healthy controls. Patients underwent ARFI elastography preoperatively. Read More

Am J Obstet Gynecol 2020 Mar 7. Epub 2020 Mar 7.

Digestive Disease and Surgery Institute, Cleveland Clinic.

Uterus transplantation is the only known potential treatment for absolute uterine factor infertility. It offers a unique setting for the investigation of immunologic adaptations of pregnancy in the context of the pharmacologic-induced tolerance of solid organ transplants, thus providing valuable insights into the early maternal-fetal interface. Until recently, all live births resulting from uterus transplantation involved living donors, with only 1 prior birth from a deceased donor. Read More