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Int J Environ Res Public Health 2022 Apr 23;19(9). Epub 2022 Apr 23.

Center of Postgraduate Medical Education, Second Department of Obstetrics and Gynecology, 01-813 Warsaw, Poland.

Placental abruption (PA) is a separation of the placenta from the uterine wall occurring with the fetus still present in the uterine cavity. It contributes to numerous neonatal and maternal complications, increasing morbidity and mortality. We conducted a retrospective study at a tertiary perinatal care center, which included 2210 cases of labor that took place in 2015 with a PA occurrence of 0. Read More

Sci Rep 2022 May 13;12(1):7944. Epub 2022 May 13.

Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, School of Medicine, Hunan Normal University, Changsha, China.

In vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) is associated with an increased risk of preterm (33rd-37th gestational week) and early preterm birth (20th-32nd gestational week). The underlying general and procedure related risk factors are not well understood so far. 4328 infertile women undergoing IVF/ICSI were entered into this study. Read More

Int J Surg Case Rep 2022 Apr 27;95:107128. Epub 2022 Apr 27.

Gynaecology-Obstetrics and Endoscopy Department, Maternity Souissi, University Hospital Center IBN SINA, University Mohammed V, Rabat, Morocco.

Background: Benckiser's hemorrhage is a serious obstetric emergency caused by rupture of one or more umbilical vessels of velamentous insertion, putting the fetus in distress and leading to rapid fetal death through exsanguination in utero. It is an uncommon condition associated with a neonatal mortality rate of 75-100%. This hemorrhage of fetal origin happens most often when the membranes rupture, whether spontaneously or artificially. Read More

Hum Reprod 2022 May 13. Epub 2022 May 13.

Department of Biomedical Sciences, Humanitas University, Pieve Emanuele-Milan, Italy.

Study Question: Is there an association between the different endometrial preparation protocols for frozen embryo transfer (FET) and obstetric and perinatal outcomes?

Summary Answer: Programmed FET protocols were associated with a significantly higher risk of hypertensive disorders of pregnancy (HDP), pre-eclampsia (PE), post-partum hemorrhage (PPH) and cesarean section (CS) when compared with natural FET protocols.

What Is Known Already: An important and growing source of concern regarding the use of FET on a wide spectrum of women, is represented by its association with obstetric and perinatal complications. However, reasons behind these increased risks are still unknown and understudied. Read More

Proc (Bayl Univ Med Cent) 2022 3;35(3):377-378. Epub 2022 Mar 3.

Texas A&M University College of Medicine, Temple, Texas.

Uterine artery pseudoaneurysms are very rare but serious malformations that can occur during pregnancy or postpartum. It is crucial to identify and treat them due to the morbid consequences associated with rupture. We present a case of a 27-year-old primigravid at 22 weeks 4 days with placenta previa and recent right salpingo-oophorectomy who presented with hematuria and right lower quadrant pain. Read More

BMC Pregnancy Childbirth 2022 May 1;22(1):378. Epub 2022 May 1.

Tianjin Central Hospital of Gynecology Obstetrics/Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin, 300100, China.

Backgroup: Frozen-thawed embryo transfer is rising worldwide. One adverse effect of programmed frozen embryo transfer (FET) reported in some studies is an increased risk of adverse obstetric and perinatal outcomes. Meanwhile, body mass index (BMI) also has adverse effect on obstetric and perinatal outcomes. Read More

Int J Womens Health 2022 22;14:593-597. Epub 2022 Apr 22.

Department of Obstetrics and Gynecology at the University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Background: Retained products of conception and placenta accreta spectrum are causes of postpartum hemorrhage. Placenta accreta spectrum is frequently managed with cesarean hysterectomy, but conservative approaches are emerging. We present a case of delayed postpartum hemorrhage secondary to a retained placenta increta. Read More

J Diabetes Complications 2022 Apr 20:108201. Epub 2022 Apr 20.

School of Nursing, Wuhan University, No.115, Donghu Road, Wuchang District, Wuhan, 430071, Hubei Province, China. Electronic address:

Aims: To explore the impact of HBV infection on maternal and infant outcomes of GDM women.

Methods: We retrospectively identified 8126 women with GDM in China from July 2017 to June 2020, and divided them into GDM with HBV infection group (n = 483) and GDM with non-HBV infection group (n = 7643). Two sample t-test and Chi-square test were used to compare differences between groups. Read More

Andrology 2022 Apr 29. Epub 2022 Apr 29.

Division of Gynecology and Reproductive Medicine, Department of Gynecology, Fertility Center, Humanitas Clinical and Research Center IRCCS, Rozzano, Milan, Italy.

Background: Nowadays, pathogenesis of preeclampsia (PE) is still unknown. Among the different etiological hypotheses, some authors proposed that it might be because of an abnormal immunologic response to a foreign fetal antigen derived from the father's spermatozoa. Indeed, the fetus is considered a semi-allograft, being one half paternally derived in its antigenicity, and the first pathogenic insult of PE may be an abnormal maternal immune response toward this semi-allogenic implant. Read More

Pak J Med Sci 2022 Mar-Apr;38(3Part-I):645-651

Jianying Yan, MD. Department of Obstetrics, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University; No. 18, Daoshan Road, Fuzhou, 350000, Fujian Province, P.R. China.

Objectives: To investigate the indications of obstetric emergency hysterectomy and analyze the clinical effects of subtotal hysterectomy and total hysterectomy.

Methods: We included 247 hospitalized women who had undergone abdominal hysterectomy due to obstetric reasons in Fujian Province Maternity and Child Health Hospital (a provincial class-A hospital) and Ningde People's Hospital (a primary Class-B hospital) between January 2002 and December 2018. We identified surgical indications and clinical characteristics of the patients. Read More

Front Med (Lausanne) 2022 5;9:837762. Epub 2022 Apr 5.

Nanjing Maternity and Child Health Care Institute, Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, Nanjing, China.

Background: With the progress of assisted reproductive technology (ART) and the increasing number of ART pregnancy, its safety has become the focus of attention. The present study aimed to explore the associations of ART pregnancy with maternal and neonatal outcomes, as compared with naturally pregnancy.

Methods: This retrospective cohort study included all pregnant women who delivered at Women's Hospital of Nanjing Medical University in 2011-2020. Read More

Nicotine Tob Res 2022 Apr 26. Epub 2022 Apr 26.

The Emmes Company, LLC.

Objectives: To examine associations of prenatal e-cigarette use to pregnancy and birth outcomes.

Methods: Currently pregnant women (n = 1,037) from Waves 1 through 4 of the Population Assessment of Tobacco and Health Study who had pregnancy or live birth outcome data in a subsequent wave (Waves 2-5; 2013 to 2019). Weighted bivariate and multivariable models \ examined associations between past 30-day tobacco use assessed during pregnancy (any past 30-day e-cigarette use, any past 30-day non-e-cigarette tobacco use, or no past 30-day tobacco use) with adverse pregnancy (miscarriage, abortion, ectopic or tubal pregnancy, stillbirth) and birth outcomes (preterm birth, low birth weight, birth defect, placenta previa, placental abruption, pre-eclampsia) reported in the subsequent wave. Read More

Comput Math Methods Med 2022 13;2022:8661324. Epub 2022 Apr 13.

Chengdu Institute of Computer Application, Chinese Academy of Sciences, Chengdu 610041, China.

Objective: To explore the application of machine learning algorithm in the prediction and evaluation of cesarean section, predicting the amount of blood transfusion during cesarean section and to analyze the risk factors of hypothermia during anesthesia recovery.

Methods: (1)Through the hospital electronic medical record of medical system, a total of 600 parturients who underwent cesarean section in our hospital from June 2019 to December 2020 were included. The maternal age, admission time, diagnosis, and other case data were recorded. Read More

J Clin Med 2022 Apr 12;11(8). Epub 2022 Apr 12.

Department of Radiology, Keimyung University Dongsan Hospital, School of Medicine, Keimyung University, Daegu 42601, Korea.

This study aimed to evaluate the feasibility and safety of temporary transcatheter balloon occlusion of bilateral internal iliac arteries (TBOIIA) during cesarean section in a hybrid operating room (OR) for placenta previa (PP) with a high risk of massive hemorrhage. This retrospective study analyzed the medical records of 62 patients experiencing PP with a high risk of massive hemorrhage (mean age, 36.2 years; age range 28-45 years) who delivered a baby via planned cesarean section with TBOIIA in a hybrid OR between May 2019 and July 2021. Read More

Fukushima J Med Sci 2022 Apr 20. Epub 2022 Apr 20.

Department of Emergency and Critical Care, Ohta Nishinouchi Hospital.

Postpartum hemorrhage is an important obstetric complication and the leading cause of maternal mortality worldwide. Occasionally, we encounter unexpected massive postpartum hemorrhage diagnosed for the first time after delivery. Therefore, it is essential to pay attention to patients with a high risk of postpartum hemorrhage. Read More

Reprod Med Biol 2022 Jan-Dec;21(1):e12456. Epub 2022 Apr 6.

Department of Obstetrics and Gynecology Teine Keijinkai Hospital Sapparo Japan.

Purpose: It is unknown whether surgery for endometriosis or recurrence of endometriosis affects obstetric outcomes.

Methods: A total of 208 pregnant women with a history of endometriosis were analyzed. Patients who had endometriomas >3 cm and no history of laparoscopic surgery for endometriosis were defined as non-surgery group ( = 60), while those who had a history of surgery for endometriosis ( = 148) were defined as surgery group. Read More

Front Surg 2022 22;9:862655. Epub 2022 Mar 22.

Department of Obstetrics, Renmin Hospital, Hubei University of Medicine, Shiyan, China.

Objective: To analyze the risk factors associated with the development of placenta praevia (PP) in first-time pregnant patients and to observe the perinatal clinical outcomes of patients.

Methods: The clinical data of 112 pregnant women with PP (PP group) and 224 pregnant women with normal placental position (general group) who delivered in our hospital from August 2016 to August 2021 were retrospectively analyzed. Baseline demographic data such as age, gestational week, uterine history, assisted reproductive technology use, pregnancy comorbidities, pre-pregnancy body mass index (BMI), smoking, alcohol consumption, placental position, educational level, work were collected from both groups, and logistic regression models were used to analyze the factors influencing the occurrence of PP in patients with first pregnancy. Read More

Acta Obstet Gynecol Scand 2022 Apr 7. Epub 2022 Apr 7.

Norwegian Research Center for Women's Health, Oslo University Hospital, Oslo, Norway.

Introduction: A peripartum hysterectomy is typically performed as a lifesaving procedure in obstetrics to manage severe postpartum hemorrhage. Severe hemorrhages that lead to peripartum hysterectomies are mainly caused by uterine atony and placenta accreta spectrum disorders. In this study, we aimed to estimate the incidence, risk factors, causes and management of severe postpartum hemorrhage resulting in peripartum hysterectomies, and to describe the complications of the hysterectomies. Read More

J Basic Clin Physiol Pharmacol 2022 Apr 8. Epub 2022 Apr 8.

Department of Public Health, School of Medicine, University of Naples Federico II, Naples, Italy.

Objectives: To evaluate anxiety and psychological impact of abnormally invasive placenta (AIP) diagnosis during pregnancy.

Methods: A cross-sectional survey study was performed to assess the psychological response of pregnant women with an antenatally AIP diagnosis. The psychological impact was measured through a visual analogue scale (VAS) for anxiety, which ranged from 0 (not at all anxious) to 100 (extremely anxious) and was referred to three questions: (1) How anxious were you the first time they counselled you about AIP?; (2) How anxious were you the day of the planned cesarean delivery in terms of morbidity/mortality?; (3) How anxious were you in terms of future sexual activities?

Results: 48 singleton pregnancies that underwent planned cesarean hysterectomy for AIP, met the inclusion criteria and were surveyed for the study. Read More

Cureus 2022 Feb 21;14(2):e22475. Epub 2022 Feb 21.

Anesthesiology/Critical Care, Hamad General Hospital, Doha, QAT.

Amniotic fluid embolism (AFE) is a rare but devastating complication of pregnancy and is associated with high morbidity and mortality. Identifiable maternal risk factors for AFE include older age, multiparity, cesarean section, and placenta previa, while fetal factors include male gender, fetal distress, and death. AFE presents with respiratory distress, seizure, and circulatory collapse and can be complicated with disseminated intravascular coagulopathy, multiorgan failure, and death. Read More

Front Endocrinol (Lausanne) 2022 16;13:837731. Epub 2022 Mar 16.

Reproduction Center, The Third Affiliated Hospital of ZhengZhou University, ZhengZhou, China.

Background: With the increasing use of frozen embryo transfer (FET), the best endometrial preparation protocol is continuously being discussed. The hormone replacement therapy (HRT) cycle and letrozole-induced ovulation (L-OI) cycle are available protocols for patients with abnormal ovulation. Previous comparisons of the two protocols have focused on pregnancy outcomes, with less attention to perinatal outcomes, and population heterogeneity was large; thus, convincing conclusions about which protocol is more appropriate could not be drawn. Read More

Asian J Surg 2022 Mar 31. Epub 2022 Mar 31.

Department of Obstetrics, Shandong Provincial Hospital, Affiliated to Shandong First Medical University, Jinan, China. Electronic address:

Radiol Case Rep 2022 May 27;17(5):1803-1809. Epub 2022 Mar 27.

Department of Radiology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

Placenta accreta spectrum (PAS) is defined as abnormal placental adherence or invasion of the myometrium or extrauterine organs. This case series will analyze MRI findings and PAS grading, in addition to emergency situations like massive hematuria and placental invasion with rupture. We report 5 cases of pregnant women with placenta previa with suspected PAS. Read More

J Obstet Gynaecol Res 2022 Apr 1. Epub 2022 Apr 1.

Department of Perinatology, University of Health Sciences/Etlik Zübeyde Hanım Women's Health Care, Training and Research Hospital, Ankara, Turkey.

Aim: In this study, we aimed to investigate the role of systemic immune-inflammation index (SII) and other inflammatory parameters in the diagnosis of placenta accreta spectrum (PAS) and its histological subtypes.

Methods: This retrospective case-control study included patients who underwent surgery for placenta previa (PP). Case group (patients with PAS) included pregnant women diagnosed with histologically confirmed PAS, whereas control group (patients with PP) included pregnant women who underwent cesarean section with a PP diagnosis, required no additional intervention during the operation. Read More

J Obstet Gynaecol Res 2022 Apr 1. Epub 2022 Apr 1.

Department of Obstetrics and Gynaecology, Kwong Wah Hospital, Kowloon, Hong Kong.

Cervical varices are a rare condition characterized by recurrent antepartum hemorrhage and less than 20 cases were reported in the literature. It is usually associated with placenta previa. We herein describe four cases of cervical varices without placenta previa. Read More

Clinics (Sao Paulo) 2022 29;77:100027. Epub 2022 Mar 29.

Departamento de Obstetrícia e Ginecologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.

Objective: To evaluate objective criteria of Magnetic Resonance Imaging (MRI) of Placenta Accreta Spectrum disorder (PAS) analyzing interobserver agreement and to derive a model including imaging and clinical variables to predict PAS.

Methods: A retrospective review including patients submitted to MRI with suspicious findings of PAS on ultrasound. Exclusion criteria were lack of pathology or surgical information and missing or poor-quality MRI. Read More

Eur Rev Med Pharmacol Sci 2022 03;26(6):1978-1983

Department of Obstetrics, Affiliated Foshan Women and Children Hospital, Southern Medical University, Foshan, Guangdong, China.

Objective: The aim of this study was to assess the association between maternal weight gain and placenta morphology in the complete placenta previa pregnancies.

Patients And Methods: This was a prospective clinical cohort study. Pregnancy weight gain was defined as the difference between delivery and at first trimester. Read More

Taiwan J Obstet Gynecol 2022 Mar;61(2):282-289

Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University, Taipei 112, Taiwan, ROC; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan, ROC; Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. Electronic address:

Objective: According to the American College of Obstetricians and Gynecologists, there has been a rapid increase in the total cesarean birth rates. The rate of placenta accreta is increasing, and previous cesarean delivery is the most common risk factor. Labor is a major challenge in cases with an abnormally invasive placenta, considering the risk of massive blood loss during cesarean delivery and patient wishes for uterine preservation. Read More

Taiwan J Obstet Gynecol 2022 03;61(2):199-200

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Female Cancer Foundation, Taipei, Taiwan; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. Electronic address:

Clin Case Rep 2022 Mar 22;10(3):e05608. Epub 2022 Mar 22.

Department of Gynecology and Obstetrics University Medical Center Mainz Mainz Germany.

Vasa previa is a rare condition. However, since the increase in assisted reproductive technologies (ARTs), clinicians are more frequently confronted with this complication. In this study, we present five cases of vasa previa prenatally diagnosed from a tertiary referral hospital with approximately 2000 births yearly. Read More