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J Eur Acad Dermatol Venereol 2020 Jun 25. Epub 2020 Jun 25.

Department of Internal Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel (VUB), Laarbeeklaan 101, 1090, Jette, Brussels, Belgium.

During the Coronavirus 2019 (COVID-19) pandemic, several associated skin conditions were reported in infected patients, including; urticaria [1], exanthema [1], erythema multiforme [2], chickenpox-like vesicles [1], pityriasis rosea [3], herpes simplex reactivation [4], erythema nodosum like Sweet's syndrome [5], Symmetrical Drug-Related Intertriginous and Flexural Exanthema [6], petechial rash [7], vasculitic purpura [7], acro-ischemia/necrosis [8], Kawasaki disease [2] and chilblain lesions [9]. Read More

Am J Emerg Med 2020 May 16. Epub 2020 May 16.

Lebanese American University, LAUMC-RH, Beirut, Lebanon. Electronic address:

Pityriasis Rosea (PR) and labyrinthitis are most commonly caused by viral infections. PR presents with a characteristic rash while labyrinthitis presents with vertigo, tinnitus and hearing loss. However, the coexistence of PR and Labyrinthitis remains an uncommon event. Read More

Dermatol Ther 2020 Jun 12:e13804. Epub 2020 Jun 12.

Department of Dermatology and Venereology, the Republic of Turkey, Health Sciences University Erzurum Regional Training and Research Hospital, Turkey.

We aim to evaluate the change in the diagnostic spectrum in dermatology outpatient applications compared to before COVID-19. All patients were enrolled from the Department of Dermatology between February 12 and May 8, 2020, the duration of 4 weeks before COVID-19 and eight weeks after were analyzed in 3 parts consisting of 4 weeks. Data obtained from the database such as age, gender, diagnoses were anonymized. Read More

Dermatol Ther 2020 May 31:e13730. Epub 2020 May 31.

Department of Dermatology, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey.

A new type of coronavirus family (SARS-CoV-2), which can be found in humans and animals, with many varieties and clinical symptoms, was first seen in Wuhan, China in late 2019, under the name novel Coronavirus Disease 2019 (COVID-19). In the literature, cutaneous symptoms related to the disease are generally emphasized. However, it is not yet known whether this new SARS-CoV-2 virus, which has entered our lives, plays a role in the etiopathogenesis of dermatological diseases. Read More

Int J Dermatol 2020 Jul 13;59(7):843-850. Epub 2020 May 13.

Department of Dermatology, Firat University Hospital, Elazig, Turkey.

Background: The use of dermoscopy for the evaluation of various inflammatory dermatoses has witnessed a gradual increase in recent years. The present study describes and highlights the importance of dermoscopic findings in the differential diagnosis of plaque psoriasis (PP), lichen planus (LP), mycosis fungoides (MF), pityriasis rosea (PR), and nummular dermatitis (ND) that mostly involve the trunk.

Methods: The study included 150 cases (PP:50, LP:30, MF:20, PR:30, ND:20). Read More

J Eur Acad Dermatol Venereol 2020 May 2. Epub 2020 May 2.

General Practitioner, Tehran, Iran.

J Cutan Med Surg 2020 Mar/Apr;24(2):207-208

5620 Division of Dermatology, Jewish General Hospital, McGill University, Montreal, QC, Canada.

Clin Dermatol 2020 Jan - Feb;38(1):35-41. Epub 2019 Oct 25.

Sector of Dermatology and Post-Graduation Course in Dermatology, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Brazil. Electronic address:

A rash is a disseminated eruption of cutaneous lesions with great variation in appearance, cause, and severity. When the physician is facing a rash, the history and physical examination of the patient are extremely important for the identification of the disease and its causal agent. There are various causes for a rash, which may be infectious, allergic, or rheumatologic, besides many others. Read More

Clin Dermatol 2020 Jan - Feb;38(1):105-112. Epub 2019 Oct 25.

Dermatologic Clinic, Policlinico San Martino, Largo R. Benzi 10, 16132 Genoa, Italy.

Any infectious illness presenting with an eruption in a pregnant patient may be associated with an increased risk of fetal loss. The viruses that can infect the placenta during maternal infection and can be transmitted to the fetus and cause congenital disease include the rubella virus, the measles virus, the varicella zoster virus, parvovirus B19, human cytomegalovirus, arboviruses, and hepatitis E virus type 1. In addition, some bacteria responsible for exanthematous diseases, like Treponema pallidum, can be transmitted during pregnancy from the mother to the fetus and cause fetal loss. Read More

Acta Dermatovenerol Alp Pannonica Adriat 2019 12;28(4):189-190

Department of Dermatology, Dr. V. P. Medical College, Hospital and Research Centre, Nashik, Maharashtra, India

Acta Dermatovenerol Alp Pannonica Adriat 2019 12;28(4):187

Dermatology Clinic, San Martino Hospital, Genoa, Italy

Indian Pediatr 2019 11;56(11):981

Dermatology Department, Farhat Hached University Hospital Ibn Jazzar Avenue, Sousse, Tunisia.

Cochrane Database Syst Rev 2019 10 30;2019(10). Epub 2019 Oct 30.

The University of Nottingham, c/o Cochrane Skin Group, A103, King's Meadow Campus, Lenton Lane, Nottingham, UK, NG7 2NR.

Background: Pityriasis rosea is a scaly, itchy rash that mainly affects young adults and lasts for 2 to 12 weeks. The effects of many available treatments are uncertain. This is an update of a Cochrane Review first published in 2007. Read More

Int J Dermatol 2020 Feb 24;59(2):e27-e28. Epub 2019 Oct 24.

Department of Dermatology, Farhat Hached University Hospital, Sousse, Tunisia.

Dermatol Online J 2019 Jul 15;25(7). Epub 2019 Jul 15.

Weill Cornell Medicine, New York, NY.

Epidermotropic B cell lymphoma represents a rare form of marginal zone lymphoma presenting as a disseminated skin rash resembling pityriasis rosea. To date there are 8 reported cases. In addition to the widespread nature of the skin rash, there is a proclivity for spleen and bone marrow involvement raising consideration regarding its categorization as a systemic lymphoma. Read More

J Allergy Clin Immunol Pract 2020 Jan 25;8(1):102-112. Epub 2019 Jul 25.

Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla.

Allergists/immunologists see a variety of skin disorders, some of which have a known immunologic basis whereas others do not. We review the prevalence, etiology, clinical presentation, and effective and low-cost care of common dermatologic conditions seen in outpatient practices. Conditions discussed include pityriasis alba, seborrheic dermatitis, rosacea, acne, tinea infections, intertrigo, lichen planus, tinea versicolor, lichen simplex chronicus, scabies, pityriasis rosea, keratosis pilaris, and seborrheic keratosis. Read More

Postepy Dermatol Alergol 2019 Apr 2;36(2):164-166. Epub 2018 Feb 2.

Department of Infectious Diseases, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.

Introduction: Pityriasis rosea (PR) is an acute, inflammatory skin disease of unknown cause. Various infectious agents including viruses have been proposed as causative agents and presence of influenza subtype H1N1 was shown in case reports with PR, but the relation was not conclusive. We hypothesited that there may be a relation between PR and H1N1, since both of them are prevalent in the same period as winter or season transitions. Read More

J Am Acad Dermatol 2020 Jan 12;82(1):156-160. Epub 2019 Jul 12.

Department of Dermatology, University of South Carolina, Charleston, South Carolina.

Background: Syphilis is often misdiagnosed clinically, and biopsies might be required.

Objective: To determine histopathologic features that distinguish secondary syphilis from pityriasis lichenoides (PL), pityriasis rosea (PR), and early mycosis fungoides (MF).

Methods: Histopathologic features of 100 cases of syphilis, 110 cases of PL, 72 cases of PR, and 101 cases of MF were compared. Read More

Acta Derm Venereol 2019 10;99(11):1053-1054

Di.S.Sal. Section of Dermatology, University of Genoa, San Martino Polyclinic Hospital, Largo Rosanna Benzi 10, IT-16132 Genoa, Italy.

Asian Pac J Cancer Prev 2019 06 1;20(6):1887-1894. Epub 2019 Jun 1.

Research Scholor, MCA Department, VBS Purvanchal University, Jaunpur, India. Email:

Objective: Skin diseases are a major global health problem associated with high number of people. With the rapid development of technologies and the application of various data mining techniques in recent years, the progress of dermatological predictive classification has become more and more predictive and accurate. Therefore, development of machine learning techniques, which can effectively differentiate skin disease classification, is of vast importance. Read More

Stud Health Technol Inform 2019 ;261:211-216

ITMO University, Saint-Petersburg, Russia.

The paper deals with neural networks for decision support in diagnosing in dermatology. There were several iterations during development. We classified six diseases using ANN: (1) Psoriasis, (2) Seborrheic dermatitis, (3) Lichen planus, (4) Pityriasis rosea, (5) Cronic dermatitis, (6) Pityriasis rubra pilaris. Read More

Br J Dermatol 2020 02 9;182(2):355-363. Epub 2019 Aug 9.

Department of Dermatology, Hôpital Henri Mondor, Assistance Publique Hôpitaux de Paris, Créteil, France.

Background: Acute exanthemas (AEs) are frequently seen; they can be caused by drugs or viruses but often the cause is unknown.

Objectives: To describe the clinical, virological and histological aspects of AEs and explore their cytokinic and metagenomic profiles.

Methods: This prospective study examined 98 patients with AE, from February to July 2014. Read More

Cutan Ocul Toxicol 2019 Dec 2;38(4):338-343. Epub 2019 Jul 2.

Department of Biochemistry, Istanbul Medipol University Hospital , Istanbul , Turkey.

Pityriasis rosea (PR) is a common, self-limiting, inflammatory skin disease with an acute onset. The etiology of PR is not yet clearly known but the defect in the oxidation system involved in many papulosquamous skin diseases may play a role. Thiol/disulfide homeostasis is a new marker of oxidative stress and has been studied in many diseases in recent years. Read More

MMW Fortschr Med 2019 May;161(8):36-42

Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein der TU München, Biedersteinerstr. 29, D-80802, München, Deutschland.

Acta Dermatovenerol Alp Pannonica Adriat 2019 Mar;28(1):15-20

Department of Dermatology, Dr. Vasantrao Pawar Medical College, Nashik, India.

Introduction: A retrospective epidemiological study was conducted to study seasonal variation in the incidence of pityriasis rosea (PR) and its temporal association with various meteorological variables, and dengue virus infection.

Methods: The study was conducted at a tertiary referral center in Guwahati, Assam, India. We searched for and retrieved all medical records of patients diagnosed with PR by dermatologists from December 1st, 2014 to July 31st, 2017. Read More

Acta Derm Venereol 2019 Jun;99(7):664-667

Department of Dermatology, Medipol University, TR-34214 Istanbul, Turkey.

Pityriasis rosea is a common acute exanthema of unknown aetiology, which causes severe anxiety. In this study, the demographic data of pityriasis rosea patients, who presented to our clinic between 2013 and 2017, were prospectively recorded. The patients with a confirmed pityriasis rosea diagnosis were followed up for 4 years in order to investigate the recurrence rate. Read More

Dermatol Pract Concept 2019 Jan 31;9(1):44-51. Epub 2019 Jan 31.

Public, Private, and Teaching Practice of Dermatology, Konstanz, Germany.

Background: Papulosquamous skin diseases can be challenging to diagnose, especially in dark skin. Dermoscopy is reported to be helpful, but few data are available on its use in skin type IV or darker.

Objective: To describe dermoscopic features in plaque-type psoriasis (PP), lichen planus (LP), and pityriasis rosea (PR) patients attending the Regional Dermatology Training Centre in Moshi, Northern Tanzania, and to compare findings with published data. Read More

Am Fam Physician 2019 02;99(4):226

An Bras Dermatol 2019 Jan-Feb;94(1):52-55

Department of Dermatology, 1st Affiliated Hospital, Anhui Medical University, Hefei, China.

Background: Pityriasis rosea is a common papulosquamous disorder. However, its etiology and pathogenesis remain unclear.

Objective: We investigate the types of inflammatory cells infiltrating the lesional skin of pityriasis rosea and demonstrate whether T-cell-mediated immunity is involved in the pathogenesis of this condition or not. Read More

Indian Dermatol Online J 2018 Nov-Dec;9(6):414-417

Department of Dermatology, AIIMS, Raipur, India.

Background: Pityriasis rosea (PR) is a common, self-limiting dermatologic disorder. The information regarding the clinical profile of the disease in India is limited because of inadequate studies.

Materials And Methods: A retrospective, record-based study on the clinical presentation of PR was conducted in a tertiary care center based in Central India. Read More

JAMA Dermatol 2018 12;154(12):1496

JAAD Case Rep 2018 Sep 14;4(8):800-801. Epub 2018 Sep 14.

DISSAL Department of Dermatology, Policlinico San Martino, Genoa, Italy.

G Ital Dermatol Venereol 2018 Sep 18. Epub 2018 Sep 18.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, I.R.C.C.S. Foundation, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

Am Fam Physician 2018 09;98(5):283-291

Thomas Jefferson University Hospital, Philadelphia, PA, USA.

Annular lesions can present in a variety of diseases. Knowledge of the physical appearance and history of presentation of these skin findings can help in the diagnosis. A pruritic, annular, erythematous patch that grows centrifugally should prompt evaluation for tinea corporis. Read More

An Bras Dermatol 2018 Sep-Oct;93(5):686-695

Postgraduate Clinical Programs, Universidad del Valle, Cali, Colombia.

Background: There is a lack of evidence to support acyclovir administration in pityriasis rosea.

Objective: To determine the efficacy of acyclovir in patients with typical pityriasis rosea.

Methods: A systematic review and meta-analysis of experimental studies was performed in MEDLINE, SCOPUS, EMBASE and others, from January 1990 to October 2016 on acyclovir for pityriasis rosea. Read More

J Dermatolog Treat 2019 May 4;30(3):288-293. Epub 2018 Sep 4.

a Department of Dermatology , Taipei Medical University Hospital , Taipei , Taiwan.

Background: Acyclovir has been reported as a potential therapy for pityriasis rosea (PR) in several clinical trials on the basis of evidence of the involvement of human herpes viruses 6 and 7.

Objective: We evaluated the efficacy of acyclovir for abating PR skin lesions within a fixed period.

Methods: We searched 4 databases for clinical trials that used oral acyclovir to treat PR and performed systematic review and meta-analysis to determine oral acyclovir's effect on skin lesions on the 14th day after commencing treatment. Read More

Dermatology 2018 22;234(1-2):31-36. Epub 2018 Jun 22.

Background: Pityriasis rosea (PR) is a self-limiting exanthematous disease associated with human herpesvirus (HHV)-6 and/or HHV-7 reactivation. In pregnant women, PR may be associated with pregnancy complications.

Objective: To determine relevant risk factors in the development of negative pregnancy outcome in PR. Read More

Evid Based Complement Alternat Med 2018 27;2018:6816981. Epub 2018 Mar 27.

Department of Scientific Research, The First Affiliated Hospital, Xi'an Medical University, Xi'an, China.

Pityriasis rosea (PR), a skin rash, causes substantial discomfort in patients. There is a lack of effective therapies for PR. A combination of ultraviolet irradiation and treatment has been shown to be a safe and effective regime for control of PR; however, the data have been largely inconsistent. Read More

Pediatrics 2018 05 19;141(5). Epub 2018 Apr 19.

Laboratoire de Virologie EA3610, University Lille and Faculté de Médecine, Centre Hospitalier Régional Universitaire de Lille, Lille, France.

Pityriasis rosea (PR) usually presents as acute exanthema with oval erythematous-squamous lesions localized on the trunk, arms, and legs with spontaneous remission. We present an unusual case of PR with frequent relapses during a period of 7 years. An 11-year-old white female patient presented with many pruritic erythematous oval lesions on her trunk. Read More

Indian Dermatol Online J 2018 Mar-Apr;9(2):131-132

Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Postepy Dermatol Alergol 2018 Feb 20;35(1):116-117. Epub 2018 Feb 20.

Department of Dermatology, IRCCS A.O.U. San Martino-IST, Genoa, Italy.

Br J Clin Pharmacol 2018 05 9;84(5):1077-1080. Epub 2018 Mar 9.

Department of Experimental Pathology, Immunology and Microbiology, Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

A 30-year-old pregnant female presented with a 2-week history of pityriasis rosea-like eruption. The rash started 2 days after the patient had started taking ondansetron 8 mg for alleviation of moderate-to-severe nausea and vomiting of pregnancy. Physical examination revealed erythematous papulosquamous lesions characterized by annular scaly margins and a dusky centre over the arms, chest, abdomen, lower back and legs. Read More

Cureus 2017 Dec 19;9(12):e1961. Epub 2017 Dec 19.

Department of Dermatology, University of California, San Diego.

Scabies, a mite infestation caused by 'Sarcoptes scabiei', most commonly presents as pruritic linear burrows where the mite has invaded the skin. Scabies variant such as bullous, crusted, hidden, incognito, nodular and scalp-mimic the other conditions. In addition, atypical presentations of scabies can masquerade as dermatitis herpetiformis, ecchymosis, Langerhans cell histiocytosis, systemic lupus erythematosus, urticaria, and urticaria pigmentosa. Read More

Dermatol Online J 2017 08 15;23(8). Epub 2017 Aug 15.

Department of Dermatology, IRCCS AOU San Martino, Genoa, Italy.

Pityriasis rosea (PR) may have atypical presentations as regards morphology and distribution of the lesions. Recently, several forms of PR considered atypical for the course of the disease have been described. Differently from the typical PR that resolves within 2-12 weeks, relapsing and persistent PR forms (lasting longer than 12 weeks) have been described in adults and children. Read More

Pediatr Dermatol 2018 Mar 13;35(2):e124-e127. Epub 2018 Feb 13.

Division of Dermatology, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Oral lesions are rarely reported in patients with pityriasis rosea. We report a case of a 3-year-old boy with clinical evidence of generalized pityriasis rosea who developed asymptomatic oral lesions similar in appearance to geographic tongue. The generalized eruption and tongue lesions resolved simultaneously within 4 weeks. Read More

Am Fam Physician 2018 Jan;97(1):Online

JAAD Case Rep 2018 Jan 19;4(1):55-57. Epub 2017 Dec 19.

Department of Dermatology, Tulane University, New Orleans, Louisiana.

Int J Dermatol 2018 Sep 29;57(9):1021-1034. Epub 2018 Jan 29.

Division of Clinical Dermatology, Mayo Clinic, Rochester, MN, USA.

Understanding the effects of age on the epidemiology of diseases primarily affecting the skin is important to the practice of dermatology, both for proper allocation of resources and for optimal patient-centered care. To fully appreciate the effect that age may have on the population-based calculations of incidence of diseases primarily affecting the skin in Olmsted County, Minnesota, and worldwide, we performed a review of all relevant Rochester Epidemiology Project-published data and compared them to similar reports in the worldwide English literature. Using the Rochester Epidemiology Project, population-based epidemiologic studies have been performed to estimate the incidence of specific skin diseases over the past 50 years. Read More

Am Fam Physician 2018 Jan;97(1):Online