Search Our Scientific Publications & Authors

Dermatol Ther (Heidelb) 2022 May 15;12(5):1091-1102. Epub 2022 Apr 15.

Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA, 19104, USA.

Parapsoriasis is an uncommon inflammatory skin disease characterized by chronic patches that may be resistant to therapy. It was primarily introduced and classified 120 years ago, and the original classification incorporated parapsoriasis and pityriasis lichenoides under the umbrella term parapsoriasis. After a major change in classification, parapsoriasis now exclusively refers to small plaque parapsoriasis (SPP) and large plaque parapsoriasis (LPP). Read More

JAAD Case Rep 2022 May 2;23:55-57. Epub 2022 Mar 2.

University of South Carolina School of Medicine, Greenville, South Carolina.

Int J Dermatol 2022 Mar 29. Epub 2022 Mar 29.

School of Medicine, Botucatu Medical School, Paulista State University (UNESP), Botucatu, São Paulo, Brazil.

Background: Leprosy is one of the main health problems in developing countries. It can show many different clinical presentations.

Case Report: A 37-yr-old woman with multiple reddish-brown papules on the lower and upper limbs, including the palms. Read More

Dermatol Ther 2022 Mar 14:e15445. Epub 2022 Mar 14.

Department of Pathology, Faculty of Medicine, Menoufia University, Shibin Al Kawm, Egypt.

J Eur Acad Dermatol Venereol 2022 06 25;36(6):e431-e433. Epub 2022 Feb 25.

Department of Dermatology, Allergology and Venereology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Cutis 2022 Jan;109(1):E8-E11

Dr. Zimmer is from Southeastern Skin Cancer and Dermatology, Huntsville, Alabama. Dr. Clay is from Dermatology Affiliates, Atlanta, Georgia. Dr. Burkemper is from the Department of Dermatology, Saint Louis University School of Medicine, Missouri.

Am J Dermatopathol 2022 Mar;44(3):174-178

Section of Dermatopathology, Department of Dermatology, Boston University School of Medicine, Boston, MA; and.

Abstract: Pityriasis lichenoides et varioliformis acuta (PLEVA) and lymphomatoid papulosis (LyP) can often demonstrate clinical and histopathologic overlap. A recent study demonstrated significant plasmacytoid dendritic cell (pDC) recruitment in lesions of PLEVA, whereas another study reported minimal pDC recruitment in lesions of LyP. To confirm the possible diagnostic value of pDCs in differentiating PLEVA and LyP, we compared the presence and distribution of pDCs and myxovirus protein A (MxA) expression (an indirect assessment of pDC activity). Read More

JAAD Case Rep 2022 Mar 6;21:26-28. Epub 2022 Jan 6.

Ronald O Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, New York.

J Eur Acad Dermatol Venereol 2022 05 25;36(5):e327-e328. Epub 2022 Jan 25.

Departments of Dermatology, Turku University Hospital and University of Turku, Turku, Finland.

Am J Dermatopathol 2022 Jun 7;44(6):411-415. Epub 2022 Jan 7.

Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Abstract: Verruca plana in its regressing phase exhibits clinical and histological features distinct from classic verruca plana, but the ways in which these features should inform treatment plans are still under investigation. We conducted a retrospective single-center analysis of 25 patients with features of classic verruca plana, or plane warts, who exhibited self-remission within 4 weeks of skin biopsy. Measures included lesion sites, clinical findings preceding regression, and histological analysis. Read More

Pediatr Dermatol 2021 Nov;38(6):e55-e57

Department of Dermatology, Farhat Hached Hospital, University of Sousse, Sousse, Tunisia.

JAAD Case Rep 2022 Feb 14;20:26-30. Epub 2021 Dec 14.

Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

J Eur Acad Dermatol Venereol 2022 Mar 24;36(3):e172-e174. Epub 2021 Nov 24.

Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, "Sapienza" University of Rome, Rome, Italy.

Australas J Dermatol 2022 Feb 9;63(1):68-73. Epub 2021 Nov 9.

Dermatology Department, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt.

Background/objectives: Pityriasis lichenoides chronica (PLC) lesions are reported to subside with post-inflammatory hypopigmentation (PIH); hence, the most widely perceived nature of hypopigmented macules in PLC is PIH. However, to the best of our knowledge, no studies describing histopathological findings in these lesions are reported in literature. The aim of this study is to evaluate the hypopigmented lesions encountered in PLC patients and to shed light on their histopathological features. Read More

Int J Clin Exp Pathol 2021 15;14(9):1010-1012. Epub 2021 Sep 15.

Department of Dermatology and Pathology, Temple/St. Luke's School of Medicine Bethlehem, Palestine.

Pityriasis lichenoides-like drug reactions simulate pityriasis lichenoides clinically and histopathologically, though important differences exist. As a rule, pityriasis lichenoides has minimal to no eosinophils. However, this case illustrates that pityriasis lichenoides-like drug reaction can present with numerous eosinophils. Read More

JAMA Dermatol 2021 11;157(11):1381-1383

Division of Dermatology, Children's National Hospital, Washington, DC.

Clin Exp Dermatol 2022 02 21;47(2):437-440. Epub 2021 Oct 21.

Dermatology Unit, Ospedale San Bortolo, Vicenza, Italy.

J Cutan Pathol 2022 Mar 21;49(3):252-260. Epub 2021 Oct 21.

Department of Dermatology, Stanford University Medical Center, Stanford, California, USA.

Background: Pityriasis lichenoides (PL) is a papulosquamous disease that affects both adults and children. Previous studies have shown a subset of this entity to have clonal T-cell populations via PCR-based assays. In this study, we sought to implement next-generation sequencing (NGS) as a more sensitive and specific test to examine for T-cell clonality within the pediatric population. Read More

Actas Dermosifiliogr (Engl Ed) 2021 Sep 28. Epub 2021 Sep 28.

Afyonkarahisar Health Sciences University, Department of Pathology, Afyonkarahisar, Turkey.

J Am Acad Dermatol 2022 02 28;86(2):433-437. Epub 2021 Sep 28.

Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina.

Acta Derm Venereol 2021 Sep 17;101(9):adv00552. Epub 2021 Sep 17.

Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, PL-50-368 Wroclaw, Poland.

Dermatopathology (Basel) 2021 Aug 14;8(3):376-389. Epub 2021 Aug 14.

Department of Pathology, Hôpital Necker-Enfants Malades, APHP, 75015 Paris, France.

The term "pseudomalignancy" covers a large, heterogenous group of diseases characterized by a benign cellular proliferation, hyperplasia, or infiltrate that resembles a true malignancy clinically or histologically. Here, we (i) provide a non-exhaustive review of several inflammatory skin diseases and benign skin proliferations that can mimic a malignant neoplasm in children, (ii) give pathologists some helpful clues to guide their diagnosis, and (iii) highlight pitfalls to be avoided. The observation of clinical-pathological correlations is often important in this situation and can sometimes be the only means (along with careful monitoring of the disease's clinical course) of reaching a firm diagnosis. Read More

Postepy Dermatol Alergol 2021 Feb 10;38(2):14-20. Epub 2021 Mar 10.

Department and Clinic of Dermatology, Carl-Thiem-Klinikum, Cottbus, Germany.

Keratinization means cytodifferentiation of keratinocytes turning into corneocytes in the stratum corneum. Disorders of keratinization (hyperkeratosis, parakeratosis and dyskeratosis) are causing many dermatological diseases, including various types of ichthyoses, pachyonychia congenita, pityriasis rubra pilaris, all subtypes of psoriasis, pityriasis lichenoides, dyskeratosis congenita, leukoplakia and keratosis follicularis, which apart from skin lesions may affect the eye's adnexae causing ectropion, entropion, blepharitis, madarosis, and trichiasis, the ocular surface causing keratitis, conjunctivitis, corneal ulceration and episcleritis, which in turn cause uveitis and various fundoscopic changes (proliferative retinopathy, retinal vasculopathy, macular oedema and birdshot chorioretinopathy). Knowledge of ocular symtoms associated with pathological keratinization is crucial, preventing sight-threatening complications such as corneal perforation, lagophthalmus, phthisis bulbi, retinal neovascularization, retinal vasculopathy and optic nerve atrophy. Read More

Int J Dermatol 2022 Apr 20;61(4):401-409. Epub 2021 Jul 20.

Department of Paediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare inflammatory dermatological disease. A case of a 13-year-old boy with FUMHD possibly triggered by mycoplasma infection is presented. Based on FUMHD cases identified in a MEDLINE literature search, demographic, treatment, and outcome data were analyzed. Read More

Ital J Dermatol Venerol 2021 Jul 20. Epub 2021 Jul 20.

Institute of Dermatology, Guangzhou Medical University, Guangzhou, Guangdong, China -

Clin Cosmet Investig Dermatol 2021 6;14:815-820. Epub 2021 Jul 6.

Department of Dermatology and Venereology, The First Affiliated Hospital, Army Medical University, Chongqing, People's Republic of China.

Syphilis is a complex, systemic infectious disease caused by subspecies . Herein, we report a rare case of secondary syphilis with probable neurosyphilis that was misdiagnosed as (PLEVA) in a 12-year-old human immunodeficiency virus (HIV) negative patient. A female patient presented to our hospital with a four-month history of relapsed systemic rash, accompanied by hair loss, arthralgia and fatigue. Read More

J Am Acad Dermatol 2022 06 29;86(6):1275-1284. Epub 2021 Jun 29.

Department of Dermatology, Kosin University College of Medicine, Busan, Korea. Electronic address:

Background: Data regarding Asian patients with mycosis fungoides (MF) are limited.

Objective: We aimed to investigate the clinical profile and long-term outcomes of patients with MF in Korea.

Methods: A retrospective review of 223 patients with MF who were followed up for more than 6 months or died of MF within 6 months of diagnosis was performed. Read More

Clin Exp Dermatol 2021 Dec 27;46(8):1561-1566. Epub 2021 Aug 27.

Department of Dermatology, AP-HP, Hôpital Henri Mondor, Créteil, France.

The classification of pityriasis lichenoides (PL) into pityriasis lichenoides et varioliformis acuta (PLEVA), PL chronica (PLC) and febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is based on both clinical and chronological features. In this retrospective monocentric study, we aimed to investigate the relevance of the classification in routine practice. We enrolled 49 patients (25 female, 24 male; median age 41 years). Read More

Actas Dermosifiliogr (Engl Ed) 2021 Jun 9. Epub 2021 Jun 9.

Servicio de Dermatología, Consorci Corporació Sanitària Parc Taulí, Universidad Autónoma de Barcelona, Spain.

Autoinflammatory keratinization disease (AiKD) is a novel clinical concept encompassing diseases with a genetic background and mixed pathogenic mechanisms of autoinflammation and autoimmunity, leading to an aberrant keratinization of the skin. Recent advances in medical genetics have revealed genetic causes and/or predisposing factors for a number of AiKD's, such as mutations in IL36RN related with pustular psoriasis, acrodermatitis continua and hidradenitis suppurativa, in CARD14 in pityriasis rubra pilaris type V and some forms of pustular psoriasis, and in NLRP1 related with familial keratosis lichenoides chronica (KLC). It is suspected that AiKD pathophysiology would also be involved in non-monogenic disorders. Read More

J Cutan Pathol 2021 Sep 4;48(9):1182-1184. Epub 2021 Jun 4.

Razi Laboratory, Rasht, Iran.

Rhabdomyomatous mesenchymal hamartoma (RMH) is a rare congenital malformation of the dermis and subcutaneous tissue. Usually, RMH occurs in the midline of the face and neck region. We described a case of RMH presenting as telangiectasia in a 57-year-old man with a history of pityriasis lichenoides chronicus. Read More