Dermatol Pract Concept 2017 Jan 31;7(1):27-34. Epub 2017 Jan 31.

Department of Dermatology, S. Nijalingappa Medical College, Bagalkot, Karnataka, India.

Background: Pityriasis lichenoides is an uncommon skin disease that presents in three different forms: pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC) and febrile ulceronecrotic-Mucha-Habermann disease. These represent a spectrum of a disease. PLEVA presents as skin eruption of multiple, small, red papules that develop into polymorphic lesions with periods of varying remissions, as well as possible sequels of hyper/hypopigmentation and varicella-like scars. Read More

Chin Med J (Engl) 2017 02;130(4):501-502

Department of Dermatology, Peking Union Medical College Hospital, Beijing 100730, China.

Hautarzt 2017 Mar;68(3):211-216

Department of Dermatology, Godavari Foundation Medical College and Research Center, DUPMCJ, Nashik, Indien.

Paraviral exanthems are distinct skin diseases due to infections with different viruses. Although no virus has been identified so far in some exanthems, the main age of manifestation, the clinical course of the exanthem, and the extracutaneous symptoms are suggestive for a viral genesis. While many viral infections are a direct result of the infection, paraviral exanthems reflect the response of the immune system to the infectious pathogens. Read More

Pediatr Dermatol 2017 Mar 30;34(2):150-155. Epub 2017 Jan 30.

Department of Dermatology, Alder Hey Children's Hospital, Liverpool, UK.

Background: Phototherapy is a well-recognized treatment in adults and children. Previous articles have reported success in treating recalcitrant skin disorders such as atopic dermatitis (AD), psoriasis, pityriasis lichenoides chronica, and vitiligo in children.

Methods: This was a retrospective review over an 18-month period from June 2012 to December 2013 of all children receiving phototherapy in a tertiary pediatric dermatology center. Read More

Clin Exp Dermatol 2017 Apr 23;42(3):303-305. Epub 2017 Jan 23.

Dermatology Department, Hospital Universitario Sanitas La Zarzuela, Universidad Francisco de Vitoria, Madrid, Spain.

Pityriasis lichenoides chronica (PLC) is an infrequent dermatosis of unknown aetiology, wholse evolution and response to treatment differs between children and adults. When PLC is recalcitrant or unresponsive to topical treatment, phototherapy is one of the main treatments used. We carried out a prospective study of adult diffuse PLC treated with narrowband ultraviolet B (NB-UVB). Read More

Rev Med Chil 2016 Sep;144(9):1214-1217

Anatomía Patológica, Hospital Clínico San Borja Arriarán, Universidad de Chile, Santiago, Chile.

Pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC) and febrile ulceronecrotic Mucha-Habermann disease (FUMHD) are considered different manifestations of the same disease. Febrile ulceronecrotic Mucha-Habermann disease is a rare, and potentially lethal illness which is characterized by fast progression of numerous papules that converge, ulcerate and form a plaque with a necrotic center, together with hemorrhagic vesicles and pustules that are associated with high fever and variable systemic symptoms. We report a 16 years old male presenting with erythematous papules with crusts and fever. Read More

Semin Diagn Pathol 2017 Jan 28;34(1):3-14. Epub 2016 Nov 28.

Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, 8036 Graz, Austria. Electronic address:

Primary cutaneous lymphomas represent a broad group of diseases with different clinical, histopathological, phenotypic, molecular, and prognostic features. All cutaneous lymphomas share the same tropism of neoplastic lymphocytes for the skin, but precise classification is paramount for proper management of the patients. Primary cutaneous lymphomas are classified according to the schemes proposed by the European Organization for Research and Treatment of Cancer (EORTC)-Cutaneous Lymphomas Task Force together with the World Health Organization (WHO) in 2005, and the WHO classification of 2008 with the 2016 update. Read More

Ann Dermatol 2016 Oct 30;28(5):540-547. Epub 2016 Sep 30.

Department of Dermatology, Kosin University College of Medicine, Busan, Korea.

Background: Pityriasis lichenoides (PL)-like skin lesions rarely appear as a specific manifestation of mycosis fungoides (MF).

Objective: We investigated the clinicopathological features, immunophenotypes, and treatments of PL-like MF.

Methods: This study included 15 patients with PL-like lesions selected from a population of 316 patients diagnosed with MF at one institution. Read More

Clin Dermatol 2016 Sep-Oct;34(5):633-9. Epub 2016 May 24.

Harvard Medical School, Dermatology Program, Division of Allergy and Immunology, Department of Medicine, Boston Children's Hospital, Boston, MA. Electronic address:

Phototherapy can be a safe and effective treatment for various skin diseases in children. Special considerations governing the use of this treatment modality in pediatric populations include patient, family, and facility-based factors that are oriented around heightened concerns with regard to safety and tolerability of treatment. Although phototherapy has been found to be effective in a wide range of dermatologic conditions affecting pediatric populations, including psoriasis, atopic dermatitis, pityriasis lichenoides, cutaneous T-cell lymphoma, and vitiligo, there is need for additional research on other conditions in which phototherapy has shown promise. Read More

Dermatol Online J 2016 May 15;22(5). Epub 2016 May 15.

Marmara University, School of Medicine, Department of Dermatology, Istanbul.

Keratitis-ichthyosis-deafness (KID) syndrome is a rare genodermatosis causing ichthyosis-like skin lesions, keratitis, and deafness. Herein, we report a patient with this rare syndrome in association with pityriasis lichenoides chronica, which was succesfully treated with narrow-band ultraviolet B phototherapy despite our concerns regarding the increased risk of squamous cell carcinoma, hyperpyrexia, and keratitis. Read More

Dermatol Ther (Heidelb) 2016 Dec 9;6(4):471-507. Epub 2016 Sep 9.

Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.

Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to their clinical presentation, i.e. Read More

JAAD Case Rep 2016 Jul 17;2(4):343-5. Epub 2016 Aug 17.

Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.

Am J Clin Dermatol 2016 Dec;17(6):583-591

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., Miami, FL, 33136, USA.

Background: Pityriasis lichenoides (PL) is a dermatologic disorder that manifests in either the acute (pityriasis lichenoides et varioliformis acuta) or the chronic form (pityriasis lichenoides chronica, also known as parapsoriasis chronica). Traditional first-line therapy consists of corticosteroids or antibiotics; however, these treatments are often accompanied with multiple side effects and may be ineffective.

Objective: The goal of this study was to review the use of phototherapy for treating PL in the pediatric population. Read More

Int J Dermatol 2016 Nov;55(11):1205-1209

ExpressMed Laboratories, Kingdom of Bahrain.

Background: Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare fulminant variant of pityriasis lichenoides et varioliformis acuta (PLEVA) characterized by a rapidly progressive course with predominant ulceronecrotic lesions associated with fever and systemic manifestations. First described by Degos in 1966, it carries a high morbidity and is potentially fatal. The exact pathogenesis is not clear, but it is proposed to be the result of hypersensitivity reaction to an infection. Read More

J Pediatr 2016 Sep 11;176:211-211.e1. Epub 2016 Jun 11.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.

Cutis 2016 May;97(5):345;347;358

Bay Dermatology/Largo Medical Center, Florida, USA.

Pityriasis lichenoides is an uncommon, acquired, idiopathic, self-limiting skin disease that poses a challenge to patients and clinicians to diagnose and treat. Several variants exist including pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC), and febrile ulcer-onecrotic Mucha-Habermann disease. Precise classification can be difficult due to an overlap of clinical and histologic features. Read More

Int J Dermatol 2016 Sep 3;55(9):1027-9. Epub 2016 Jun 3.

Department of Dermatology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia.

JAAD Case Rep 2016 Mar 22;2(2):181-5. Epub 2016 Apr 22.

Department of Dermatology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Expert Rev Anti Infect Ther 2016 Jun;14(6):601-11

c School of Public Health and Primary Care , The Chinese University of Hong Kong and Prince of Wales Hospital , Shatin , Hong Kong.

Introduction: Paraviral exanthems are skin diseases suspected to be caused by viruses, with a single virus-exanthem relationship not universally accepted. Although most paraviral exanthems are self-remitting, accurate diagnoses are important as some patients might develop complications. Some of the differential diagnoses might cause serious complications, and some paraviral exanthems might lead to complications for at-risk groups such as pregnant women. Read More

Am J Clin Dermatol 2016 Aug;17(4):319-27

Department of Dermatology, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030-4095, USA.

Background: Lymphomatoid papulosis (LyP) is a lymphoproliferative disorder that is rare among adults and even rarer among children. In adults, LyP is associated with an increased risk of secondary lymphomas.

Objective: The aim of this systematic review was to describe the clinical and histopathological features of LyP in children, to assess the risk of associated lymphomas, and to compare the disease to the adult form. Read More

Int J Dermatol 2016 Oct 7;55(10):1115-8. Epub 2016 Apr 7.

Temple University School of Medicine, Philadelphia, PA, USA.

Background: Certain dermatologic conditions are known to show seasonal variations in frequency, the reasons for which are unclear but in some cases may be attributable to changes in ambient weather conditions.

Objectives: The current study was conducted to determine whether seasonal trends might exist for dermatologic conditions including erythema multiforme, guttate psoriasis, erythema dyschromicum perstans (ashy dermatosis), pityriasis lichenoides, and pityriasis rosea.

Methods: Data were derived from a 15-year retrospective review of electronic records from a large dermatopathology laboratory located in the mid-Atlantic region of the USA. Read More

Br J Dermatol 2016 Oct 20;175(4):807-9. Epub 2016 Jun 20.

Department of Dermatology, University of Toronto, Toronto, ON, Canada.

Ann Dermatol Venereol 2016 Apr 14;143(4):311-7. Epub 2016 Mar 14.

Département de pathologie, hôpital Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.

Hautarzt 2016 Apr;67(4):293-7

Klinik für Dermatologie, Venerologie und Allergologie, Kinderdermatologische Ambulanz, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.

Erythematosquamous dermatoses in adolescents comprise a wide range of differential diagnoses. Age-typical variations of the clinical manifestation, the need to differentiate common conditions from rare diseases as well as the tremendous psychosocial impact which the patients perceive especially in this vulnerable period of life can become major challenges for pediatric dermatologists. This article summarizes key features of common erythematosquamous dermatoses and less frequent skin diseases occurring during adolescence. Read More

J Dtsch Dermatol Ges 2016 Feb 20;14(2):184-6. Epub 2016 Jan 20.

Department of Dermatology, Venereology, and Allergology, HELIOS St. Elisabeth Hospital, Oberhausen. Germany.

Int J Dermatol 2016 Jul 23;55(7):729-38. Epub 2015 Dec 23.

Department of Dermatology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare severe variant of pityriasis lichenoides et varioliformis acuta characterized clinically by aggressive ulceronecrotic skin lesions associated with high fever and histologically by features typical of pityriasis lichenoides et varioliformis acuta. Despite the continuous addition of new case reports, no definite diagnostic criteria have been established, and an optimum treatment is still waiting. Herein, we review the different aspects of this rare entity, including pathogenesis, clinical and histopathological features, differential diagnosis, course, prognosis, and outcome. Read More

Antivir Ther 2016 15;21(3):273-5. Epub 2015 Dec 15.

Department of Dermatology, School of Medicine, Medical University of Silesia, Katowice, Poland.

To our knowledge, there are no previously published cases of enteroviral infection complicated by pityriasis lichenoides et varioliformis acuta (PLEVA). A 30-year-old woman is reported with a severe form of PLEVA, preceded by hand, foot and mouth disease. Immunosuppressive treatment with cyclosporin A resulted in rapid clinical improvement. Read More

Pediatr Dermatol 2015 Nov-Dec;32(6):e307-8. Epub 2015 Oct 8.

Department of Dermatology, Center for Health and Healing, Oregon Health and Science University, Portland, Oregon.

Febrile ulceronecrotic Mucha-Habermann disease (FUMHD), a severe form of pityriasis lichenoides et varioliformis acuta (PLEVA), featuring large, ulcerative, necrotic skin plaques, high fever, and other systemic symptoms, is a rare disorder of unknown etiology. No randomized controlled trials have established treatment guidelines and multiple modalities are often employed, making it difficult to assess the efficacy of any single agent. We report two cases of this condition in which treatment with methotrexate plus antibiotic treatment for superinfection led to rapid improvement. Read More

J Cutan Pathol 2016 Apr 22;43(4):303-12. Epub 2015 Dec 22.

Department of Dermatology, The Warren Alpert Medical School of Brown University, Providence, RI, USA.

Arch Pediatr 2016 Jan 6;23(1):82-5. Epub 2015 Nov 6.

Service de pédiatrie générale, CHU Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France. Electronic address:

Pityriasis lichenoides et varioliformis acuta (PLEVA) is an inflammatory skin disease that is unknown to pediatricians. The ulceronecrotic febrile form is a rare and potentially lethal variant. We report the case of a 7-year-old boy with a papulovesicular eruption lasting for 4 weeks, secondarily associated with ulcers and necrotic crusts, fever, and systemic signs. Read More

Actas Dermosifiliogr 2016 Mar 29;107(2):167-9. Epub 2015 Oct 29.

Servicio de Anatomía Patológica, Complejo Hospitalario de Jaén, Jaén, España.

Case Rep Dermatol Med 2015 27;2015:357973. Epub 2015 Aug 27.

Department of Pathology, Faculty of Medicine, Osmangazi University, Eskişehir, Turkey.

Febrile Ulceronecrotic Mucha-Habermann disease is a rare and potentially fatal variant of pityriasis lichenoides et varioliformis acuta and is characterized by high fever, constitutional symptoms, and acute oncet of ulceronecrotic lesions. We present an 11-year-old male with Febrile Ulceronecrotic Mucha-Habermann disease who was cured with methotrexate and review the use of methotrexate for this disorder in the pediatric age group with the relevant literature. Read More

J Pak Med Assoc 2015 Sep;65(9):1011-3

Department of Pathology, Turgut Ozal University, Faculty of Medicine, Ankara, Turkey.

Lichen striatusis a rare linear papulardermatosis that primarily occurs in children. The lesions have a linear distribution following Blaschko's lines. Pityriasis lichenoides is an uncommon benign skin disorder with two major variants: acute and chronic. Read More

G Ital Dermatol Venereol 2015 Oct;150(5):521-31

Dermatology Clinic, University of Catania, A.O.U. Policlinico Vittorio Emanuele, Catania, Italy -

Dermatoscopy is a non-invasive technique that allows a rapid and magnified in vivo observation of the skin surface. By definition, it is performed with handheld devices (dermatoscopes) allowing X10 magnification. More expensive, computer-assisted digital systems (videodermatoscopes) may be equipped with lenses that ensure magnifications up to X1000; in this case the term videodermatoscopy is generally used. Read More

An Bras Dermatol 2015 May-Jun;90(3 Suppl 1):181-4

Hospital da Polícia Militar de Minas Gerais, Belo Horizonte, MG, BR.

The etiology of pityriasis lichenoides is unknown. One of the accepted theories admits that PL is an inflammatory response to extrinsic antigens such as infectious agents, drugs and vaccines. In recent medical literature, only the MMR vaccine (Measles, Mumps and Rubella) was associated with the occurrence of this disease. Read More

J Cutan Pathol 2015 Aug 12. Epub 2015 Aug 12.

Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

Reactive lymphoid infiltrates of the skin composed predominantly of gamma-delta (γδ) T cells are not well described in the literature. Herein we report a case of an otherwise healthy 4-year-old male who presented with a waxing and waning papular rash characterized by small, discrete crusted papules spread across his trunk, face and extremities. Clinical evaluation revealed no evidence of systemic disease. Read More

Rev Chil Pediatr 2015 Mar-Apr;86(2):121-5

Residente de Dermatología, P. Universidad Católica de Chile.

Introduction: Pityriasis lichenoides is a benign inflammatory disease of unknown etiology. There are two types of this condition: an acute form (PLEVA = pityriasis lichenoides et varioliformis acuta) and a chronic one (PLC = pityriasis lichenoid chronica). Both are more common in children and young adults. Read More

Pediatr Dermatol 2015 Nov-Dec;32(6):e238-41. Epub 2015 Jul 29.

Department of Dermatology, Northwest Hospital, Xi'an Jiaotong University, Xi'an Shaanxi, China.

A 9-year-old boy presented with a history of keratotic violaceous plaques on the limbs and face for 8 years that had gradually progressed to erosive nodules on the extremities for 2 years. Several biopsies revealed hyperkeratosis, liquefactive degeneration of the basal layer, and a bandlike predominantly lymphocytic infiltrate. Based on the clinical and histologic findings, the patient was diagnosed with keratosis lichenoides chronica, a rare chronic dermatosis that is particularly uncommon in childhood. Read More

G Ital Dermatol Venereol 2015 Oct 18;150(5):533-46. Epub 2015 Jun 18.

Department of Experimental and Clinical Medicine Institute of Dermatology University of Udine, Udine, Italy -

Beside to traditional use, dermoscopy is more and more used in the assessment of other "general" dermatologic conditions, namely scalp and hair disorders (trichoscopy), nails abnormalities (onychoscopy), skin infections and infestations (entomodermoscopy), and cutaneous inflammatory diseases (inflammoscopy). Among the list of new applications of dermoscopy, the study of inflammatory dermatoses is probably the most promising topic in terms of development and usefulness, considering the large number of such disorders and the frequent problems in their differential diagnosis which the dermatologist encounters in own daily clinical practice. In this paper, we report selected relatively common clinical differential diagnosis issues concerning inflammatory dermatoses (and some clinically related noninflammatory conditions), analysing them by a dermoscopic point of view in order to assist their noninvasive resolution according to the available literature data and our personal experience, including papulosquamous dermatoses (guttate psoriasis, pityriasis lichenoides chronica, pityriasis rosea, lichen planus, lymphomatoid papulosis, classic pityriasis rubra pilaris, papulosquamous sarcoidosis, disseminated forms of porokeratosis and papulosquamous chronic GVHD), dermatoses presenting with erythematous-desquamative patches/plaques (plaque psoriasis, eczematous dermatitis, pityriasis rosea, mycosis fungoides, subacute cutaneous lupus erythematosus), palmar psoriasis vs. Read More

Dermatology 2015 6;231(2):152-7. Epub 2015 Jun 6.

Pediatric Department of Southern Switzerland, Bellinzona, Switzerland.

Background: Maculopapular or urticarial eruptions and erythema multiforme sometimes occur in patients affected with Mycoplasma pneumoniae respiratory infections. Further eruptions have also been reported.

Objective: To review the literature addressing M. Read More

Acta Derm Venereol 2016 Jan;96(1):136-7

Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs,Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Jiangwangmiao Street 12, Nanjing, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Jiangwangmiao Street 12, Nanjing, Jiangsu 210042, China.

Pediatr Dermatol 2015 Sep-Oct;32(5):579-92. Epub 2015 Mar 26.

Department of Dermatology, Columbia University, New York, New York.

Pityriasis lichenoides (PL) is a skin condition of unclear etiology that occurs not uncommonly in childhood. It is often classified into the acute form, pityriasis lichenoides et varioliformis acuta (PLEVA), and the chronic form, pityriasis lichenoides chronica (PLC). We performed a comprehensive review of the English-language literature using the PubMed database of all cases of childhood PL reported from 1962 to 2014 and summarized the epidemiology, clinical features, treatment options, and prognosis of this condition in children. Read More

Case Rep Dermatol Med 2015 18;2015:168063. Epub 2015 Feb 18.

Rheumatology Unit, Fundación Valle del Lili, Carrera 98 N. 18-49, Cali, Colombia.

We present a 74-year-old female patient who developed a pityriasis lichenoides chronica (PLC) during etanercept therapy. This association is not described in the literature and might be considered in the spectrum of cutaneous adverse reactions of etanercept. Read More

Clin Exp Dermatol 2015 Oct 16;40(7):804-6. Epub 2015 Feb 16.

Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Italy.

Clinical differentiation between pityriasis lichenoides chronica (PLC) and guttate psoriasis (GP) may sometimes be a difficult task, which often requires histological analysis to reach a definitive diagnosis. In this study, PLC and GP lesions were examined using dermoscopy, and the significance of specific dermoscopic findings was investigated in order to facilitate their differentiation and decrease the number of cases requiring biopsy. We found that the incidence of orange-yellowish structureless areas, focal dotted vessels and nondotted vessels was statistically significant in PLC, while the incidence of diffuse dotted vessels was statistically significant in GP. Read More

Br J Dermatol 2015 Feb;172(2):315-6

Department of Medicine and Department of Microbiology and Immunology, James Graham Brown Cancer Center, University of Louisville, 505 South Hancock Street, Clinical & Translational Research Building, Room 327H, University of Louisville, Louisville, KY, 40202, U.S.A.

Infection 2015 Oct 28;43(5):583-8. Epub 2015 Jan 28.

Department of Pediatrics, University Medicine Greifswald, Ferdinand-Sauerbruchstrasse 1, 17475, Greifswald, Germany.

We present the youngest pediatric patient so far with febrile ulcerative Mucha-Haberman disease (FUMHD) after an admitting clinical picture of hemorrhagic varicella infection. With a time to diagnosis of 25 days, the 20-month-old boy responded to low dose cyclosporine and prednisolone given for 3 months and is free of disease after 4 years of follow up. We describe a polyclonal CD8+ T cell response with elevated pro-inflammatory cytokines and a fivefold upregulation of the high-affinity Fc receptor type I (CD64) on granulocytes. Read More

Rom J Morphol Embryol 2014 ;55(3 Suppl):1085-92

Department of Microscopic Morphology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania;

Background: Parapsoriasis represents a group of cutaneous disorders that shows variable clinical aspects somehow resembling to psoriasis, how is reflecting by its name. It was first named by Brocq, in 1902, as an entity with three components: pityriasis lichenoides, small plaque parapsoriasis and large plaque parapsoriasis. Nowadays, under the name of parapsoriasis are included only the last two categories, that are considered disorders characterized by the presence of a mononuclear infiltrate in the dermis, composed of T-cells. Read More

BMJ Case Rep 2014 Dec 23;2014. Epub 2014 Dec 23.

Coimbra University Hospital, Coimbra, Portugal.

Primary cutaneous lymphomas (PCLs) are exceedingly rare in children and adolescents, with mycosis fungoides (MF) being the most frequent PCL diagnosed in childhood. There are numerous unusual clinical variants of MF, including the hypopigmented type form (HMF). HMF is exceptional overall, but comparatively common among children. Read More

Exp Ther Med 2014 Dec 7;8(6):1927-1933. Epub 2014 Oct 7.

Department of Pathology, The Third Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710068, P.R. China.

The aim of this study was to improve the level of diagnosis and differential diagnosis of lymphomatoid papulosis (LyP). Two cases of type B LyP were identified and the literature was reviewed to summarize the clinical outcomes and pathology of LyP and its treatment. The two patients exhibited symptoms with papulonodular lesions, the centers of which gradually underwent ulceration and necrosis. Read More

Br J Dermatol 2015 Feb 15;172(2):372-9. Epub 2014 Dec 15.

Department of Dermatology, Northwestern University Feinberg School of Medicine, 676 North St. Clair Street, Suite 1600, Chicago, IL, 60611, U.S.A.

Background: T cells with a γδ phenotype have been associated with aggressive lymphomas. Yet, inflammatory skin disorders and low-grade lymphoproliferative disorders have rarely been described with a predominant γδ T-cell infiltrate.

Objectives: To review our experience and determine the clinical relevance of the γδ T-cell phenotype in lymphomatoid papulosis (LyP) and pityriasis lichenoides (PL). Read More