Search Our Scientific Publications & Authors

J Cosmet Dermatol 2021 May 3. Epub 2021 May 3.

Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Background: Epidemiologic data derived from population-based studies are very important to understand human diseases and their implications. Highlighting skin problems by identifying their incidence and prevalence is vital to direct suitable medical attention toward them.

Aim: The aim of the study was to detect the prevalence and most common causes of hypopigmentation in primary school children in Zagazig City. Read More

Ital J Dermatol Venerol 2021 Feb 23;156(1):62-67. Epub 2020 Nov 23.

Department of Dermatology, Baghdad Medical City Complex, Baghdad, Iraq.

Background: Nevus depigmentosus (ND) is an uncommon congenital nonprogressive hypopigmented skin disorder that can be seen anywhere on the body. We considered other depigmenting disorders and focused on distinguishing ND from vitiligo and tuberous sclerosis complex in infancy.

Methods: The diagnosis of patients with nevus depigmentosus was made differentiating it from nevus anemicus, pityriasis alba, tuberous sclerosis complex, vitiligo and other depigmenting disorders. Read More

Medicina (Kaunas) 2020 Jul 17;56(7). Epub 2020 Jul 17.

Molecular Medicine Laboratory, Doctorado en Ciencias con Orientación en Medicina Molecular, Unidad Académica de Medicina Humana y C.S., Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.

: Pytiriasis alba (PA) is a common skin disorder which affects 80% of children between six and 16 years. The etiology of PA is unclear, but hypo-pigmented patches in photo-exposed zones characterize the disease. Because the high ultraviolet exposition of the skin promotes an acute inflammatory response and an increase of oxidative stress (OS), this study aimed to evaluate the expression levels of inflammatory and OS-related genes in skin biopsies, and their association with PA. Read More

Clin Dermatol 2020 May - Jun;38(3):354-356. Epub 2019 Jul 11.

Rutgers New Jersey Medical School, Newark, New Jersey, USA; Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA; Department of Dermatology, Rutgers New Jersey Medical School, Newark, New Jersey, USA. Electronic address:

Although pityriasis alba is a common dermatologic condition, its pathogenesis is poorly understood, and there are many discrepancies in the literature. To assess the effect of the duration of disease on the histologic findings, a search of cases labeled "pityriasis alba" was performed on any cases submitted to our dermatopathology laboratory. Of 179 cases of pityriasis alba, five cases identified the duration of the disease, when the biopsy was taken. Read More

J Trace Elem Med Biol 2020 May 30;59:126422. Epub 2019 Oct 30.

Department of Family medicine, Faculty of Medicine, Zagazig University, Egypt.

Background: Pityriasis Alba (PA) is a common skin disorder affecting the children and it has multiple risk factors.

Objectives: To assess the serum levels of trace elements (copper, zinc, and magnesium) and hemoglobin (Hb) level in patients with PA.

Method: This is a case control study; 110 participants (55 cases and 55 controls) were recruited from pediatric dermatology and family medicine clinics, Cairo university hospitals. Read More

J Pediatr Health Care 2019 Nov - Dec;33(6):727-737

Children with skin of color represent a large proportion of the pediatric population. There are numerous skin conditions that commonly occur in this population, including but not limited to acne, atopic dermatitis, pityriasis alba, tinea versicolor, progressive macular hypomelanosis, traction alopecia, and confluent and reticulated papillomatosis. This article highlights the clinical presentations of these conditions in skin of color and briefly addresses pathophysiology and treatment modalities. Read More

Pediatr Dermatol 2020 Jan 23;37(1):230-232. Epub 2019 Oct 23.

IQRAA Aesthetics, Department of Dermatology, IQRAA International Hospital and Research Centre, Calicut, India.

Epidermodysplasia verruciformis (EV) manifests early in childhood as pityriasis versicolor (PV)-like macules on sun-exposed sites such as the face. These hypopigmented lesions closely resemble commoner pediatric dermatoses such as PV or pityriasis alba. In this report of two cases, we describe the distinguishing dermoscopic features of PV-like macules in EV. Read More

Int J Clin Pract 2020 Feb 30;74(2):e13441. Epub 2019 Oct 30.

Department of Immunology of Parasitic Diseases, the Research Institute of Epidemiology, Microbiology and Infectious Diseases, Tashkent, Uzbekistan.

Background: The aetiology of pityriasis alba (PA) remains uncertain, and children are at risk for PA and intestinal parasites.

Aim: To determine the prevalence of intestinal parasites in PA patients and to evaluate their possible role in PA pathogenesis.

Methods: Overall, 180 PA patients and 100 healthy individuals were enrolled. Read More

J Allergy Clin Immunol Pract 2020 01 25;8(1):102-112. Epub 2019 Jul 25.

Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla.

Allergists/immunologists see a variety of skin disorders, some of which have a known immunologic basis whereas others do not. We review the prevalence, etiology, clinical presentation, and effective and low-cost care of common dermatologic conditions seen in outpatient practices. Conditions discussed include pityriasis alba, seborrheic dermatitis, rosacea, acne, tinea infections, intertrigo, lichen planus, tinea versicolor, lichen simplex chronicus, scabies, pityriasis rosea, keratosis pilaris, and seborrheic keratosis. Read More

Dermatol Reports 2019 Jan 21;11(1):7916. Epub 2018 Dec 21.

Faculty of Medicine, Mutah University, Jordan.

One of the most frequent complaints in dermatology clinics is the eruption of hypopigmented patchy skin lesions. The aim of the study was to investigate the utility of dermoscopy in common hypopigmented macular diseases. Patients with the followings diseases were examined by dermoscopy: vitiligo, pityriasis alba, nevus depigmentosus, achromic pityriasis versicolor, idiopathic guttate hypomelanosis, and extragenital guttate lichen sclerosus. Read More

Indian J Dermatol Venereol Leprol 2020 Jul-Aug;86(4):386-391

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

Background: Hypopigmented macules are seen in a variety of disorders and the diagnosis rests on clinicopathological correlation. However, some cases are difficult to classify and pose a diagnostic challenge.

Aim: To describe the clinical and histopathological features of patients with hypopigmented macules and follicular spongiosis on histopathology. Read More

J Am Acad Dermatol 2019 Feb 1;80(2):390-401. Epub 2018 Oct 1.

Department of Dermatology, Preventive Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern Medicine Multidisciplinary Eczema Center, Chicago, Illinois. Electronic address:

Background: Previous studies found conflicting results about the commonality of different atopic dermatitis (AD) signs and symptoms.

Objective: To determine the prevalences of AD characteristics and differences by region and age.

Methods: A systematic review was performed of all published studies in MEDLINE, EMBASE, SCOPUS, LILACS, Cochrane, China National Knowledge Infrastructure, Taiwan Electronic Periodical Services, and CiNii that analyzed the proportion of AD characteristics. Read More

Clin Dermatol 2018 Sep - Oct;36(5):631-640. Epub 2018 Jun 1.

Department of Dermatology, Mt Sinai West, Icahn School of Medicine at Mt Sinai, New York, NY. Electronic address:

Atopic dermatitis is a common chronic pruritic inflammatory skin disorder, characterized by an abnormal skin barrier, immune dysfunction, and an altered skin microbiome. Atopic dermatitis may be seen in conjunction with a variety of other skin disorders due to the complex pathogenesis of atopic dermatitis, involving genetic and environmental factors that are associated with immune dysfunction, barrier defects, and altered skin microbiomes. Skin disorders associated with atopic dermatitis include diseases sharing similar genetic origins like ichthyosis vulgaris, infectious diseases such as impetigo, and eczema herpeticum, in addition to the cutaneous autoimmune diseases, alopecia areata, and vitiligo. Read More

Malays Fam Physician 2018 30;13(1):49-51. Epub 2018 Apr 30.

MRCP (UK), Adv. M Derm (UKM) Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Selangor Malaysia. E-mail:

Am Fam Physician 2017 Dec;96(12):797-804

Norton Audobon Hospital, Louisville, KY, USA.

Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules. These conditions are generally benign but can be distressing to patients. Read More

Kathmandu Univ Med J (KUMJ) 2016 Jul-Sept.;14(55):249-253

Department of Pediatrics, Manipal College of Medical Science, Pokhara, Nepal.

Background A major earthquake occurred in Nepal on 25th April 2015 with magnitude of 7.8 causing mass panic amongst people. Objective To analyze scenario, experience and disease pattern of Post Earthquake camp at Gyampesal, Gorkha. Read More

Mult Scler 2018 02 28;24(2):231-233. Epub 2017 Jul 28.

Multiple Sclerosis Center, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

We report the case of a 42-year-old female patient who developed peculiar skin lesions due to subcutaneous polyethylene glycol (PEG) interferon beta-1a. The dermatological examination showed hypochromic macules that had coalesced into a 10-cm-diameter patch. On the abdomen injection sites, there was a greyish diffuse hyperpigmentation arranged irregularly in annular macules. Read More

Dermatol Clin 2017 Jul 4;35(3):351-363. Epub 2017 May 4.

Department of Pediatric Dermatology, National Institute of Pediatrics, Insurgentes Sur 3700-C, Insurgentes Cuicuilco, México City 04530, México.

Atopic dermatitis is the leading cause of pediatric dermatology visits in developed nations. Recurrent, itchy rashes in typical locations and a family/personal history of atopy helps to identify children with disease. Most cases (85%) are diagnosed by age 5 years. Read More

Clin Dermatol 2016 Nov - Dec;34(6):690-697. Epub 2016 Jul 12.

Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL. Electronic address:

There are numerous skin conditions that occur commonly in children with ethnic skin, including vitiligo, progressive macular hypomelanosis, pityriasis alba, acne keloidalis nuchae, pseudofolliculitis barbae, and keloids. Though these conditions occur in both children and adults, children may have different patterns of clinical presentation and response to therapy. In caring for such patients, important treatment considerations include side effects of systemic medications and tolerability of invasive procedures. Read More

Postepy Dermatol Alergol 2016 Jun 17;33(3):176-81. Epub 2016 Jun 17.

Department of Family Medicine, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey.

Introduction: Skin lesions may be of dermatological importance, affect appearance, and cause problems communicating with peers and may be especially more significant in childhood.

Aim: Information on the prevalence of pediatric dermatoses in Western Turkey. This study was aimed to define the existing data. Read More

Indian J Dermatol 2015 Nov-Dec;60(6):635

Department of Dermatology, Venereology and Leprosy, Government Medical College, Surat, Gujarat, India.

Background: Dermatologic conditions have different presentation and management in pediatric age group from that in adult; this to be studied separately for statistical and population based analysis.

Objective: To study the pattern of various dermatoses in infants and children in tertiary health care center in South Gujarat region.

Materials And Methods: This is a prospective study; various dermatoses were studied in pediatric patients up to 14 years of age attending the Dermatology OPD of New Civil Hospital, Surat, Gujarat over a period of 12 months from June 2009 to June 2010. Read More

Pediatr Dermatol 2015 Nov-Dec;32(6):786-91. Epub 2015 Oct 19.

Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.

Pityriasis alba (PA) is a skin disorder that affects children and adolescents. Although it is common worldwide, its incidence is markedly higher in darker skin phototypes. Its characteristic features include an extended, multistage course and spontaneous remissions and recurrences. Read More

Am J Dermatopathol 2015 Nov;37(11):834-40

*Dermatopathology Unit, Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt; Departments of †Pathology, and ‡Dermatology, National Research Centre, Cairo, Egypt.

Hypopigmented mycosis fungoides (HMF) is an uncommon variant of mycosis fungoides with an unknown exact frequency. We aimed to study the frequency of HMF in a cohort of Egyptian patients presenting to a tertiary care center in Cairo, Egypt, with hypopigmented lesions of the trunk. Hundred patients with hypopigmented lesions involving the trunk (with or without other sites involvement) were subjected to thorough clinical and histopathological examination. Read More

J Lasers Med Sci 2014 ;5(1):8-12

Department of Dermatology, Jahrom University of Medical Sciences, Jahrom, Iran.

308nm xenon-chloride excimer laser, a novel mode of phototherapy, is an ultraviolet B radiation system consisting of a noble gas and halide. The aim of this systematic review was to investigate the literature and summarize all the experiments, clinical trials and case reports on 308-nm excimer laser in dermatological disorders. 308-nm excimer laser has currently a verified efficacy in treating skin conditions such as vitiligo, psoriasis, atopic dermatitis, alopecia areata, allergic rhinitis, folliculitis, granuloma annulare, lichen planus, mycosis fungoides, palmoplantar pustulosis, pityriasis alba, CD30+ lympho proliferative disorder, leukoderma, prurigo nodularis, localized scleroderma and genital lichen sclerosus. Read More

BMJ Case Rep 2014 Dec 23;2014. Epub 2014 Dec 23.

Coimbra University Hospital, Coimbra, Portugal.

Primary cutaneous lymphomas (PCLs) are exceedingly rare in children and adolescents, with mycosis fungoides (MF) being the most frequent PCL diagnosed in childhood. There are numerous unusual clinical variants of MF, including the hypopigmented type form (HMF). HMF is exceptional overall, but comparatively common among children. Read More

JAMA Dermatol 2014 Nov;150(11):1197-201

School of Public Health, The Chinese University of Hong Kong and The Prince of Wales Hospital, Hong Kong.

Importance: Recognition of different clinical presentations of viral and virally triggered ("paraviral") exanthems is necessary for patients to be appropriately diagnosed and counseled.

Observations: Nine children presented with eruptions of hypopigmented macules following coryzal symptoms. Other diagnostic considerations, such as pityriasis alba, pityriasis versicolor, and progressive macular hypomelanosis, were excluded. Read More

An Bras Dermatol 2014 Mar-Apr;89(2):245-8

Universidade do Estado do Pará, Belém, PA, Brazil.

Background: Pityriasis alba affects 1% of the world population and about 9.9% of the children in Brazil. However, its etiology remains uncertain. Read More

Int J Dermatol 2014 May;53(5):609-16

Department of Dermatology, Venereology and Andrology, Ain Shams University, Cairo, Egypt.

Objectives: Information on prevalences of pediatric dermatoses in Egypt is scanty. This study aimed to supplement existing data.

Methods: A cross-sectional study was conducted in Damietta, Egypt between October 2011 and March 2012. Read More

J Cutan Med Surg 2014 Mar-Apr;18(2):91-108

Background: Topical vitamin D is approved by the US Food and Drug Administration for the treatment of psoriasis but is also used off-label in the treatment of a variety of cutaneous diseases despite a lack of evidence-based guidelines.

Objective: The objective of this study was to provide evidence-based clinical guidelines for the off-label use of topical vitamin D in the treatment of dermatologic disease.

Methods: A systematic literature review was conducted via the MEDLINE, Embase, and CENTRAL databases for off-label uses of topical vitamin D analogues in the treatment of dermatologic disease other than psoriasis. Read More