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    Relapsing Pityriasis Rosea With HHV-7 Reactivation in an 11-Year-Old Girl.
    Pediatrics 2018 Apr 19. Epub 2018 Apr 19.
    Laboratoire de Virologie EA3610, University Lille and Faculté de Médecine, Centre Hospitalier Régional Universitaire de Lille, Lille, France.
    Pityriasis rosea (PR) usually presents as acute exanthema with oval erythematous-squamous lesions localized on the trunk, arms, and legs with spontaneous remission. We present an unusual case of PR with frequent relapses during a period of 7 years. An 11-year-old white female patient presented with many pruritic erythematous oval lesions on her trunk. Read More

    The efficacy of a pseudo-ceramide and eucalyptus extract containing lotion on dry scalp skin.
    Clin Cosmet Investig Dermatol 2018 6;11:141-148. Epub 2018 Apr 6.
    Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan.
    Objective: Dry and scaly conditions on the scalp are often observed in patients with atopic dermatitis, seborrheic dermatitis and/or pityriasis capitis. Those scalp lesions often exhibit low barrier function and reduced ceramide levels. Therefore, a clinical study was conducted to evaluate the efficacy of topical application of a pseudo-ceramide and eucalyptus extract-containing lotion on the scalps of patients with skin diseases. Read More

    Prevalence of skin diseases amongst Moroccan fishermen.
    Int Marit Health 2018 ;69(1):22-27
    Graduate School of Health Engineering, 24 rue Lafontaine, Quartier Racine, 20100 Casablanca, Morocco.
    Background: The main objective was to evaluate the prevalence of skin diseases amongst fishermen, to specify the different clinical forms, associations and most frequent localisations, and to identify potential aetiological factors. The secondary objectives were to assess the knowledge, attitudes and practices of seafarers regarding occupational dermatoses to conduct information, awareness and education campaigns on risk factors and behaviours and to propose adapted prevention.

    Materials And Methods: This cross-sectional survey involved 1102 artisanal fishermen who attended the annual legal medical consultation at the occupational health service. Read More

    Biologics for pityriasis rubra pilaris treatment: a review of the literature.
    J Am Acad Dermatol 2018 Mar 30. Epub 2018 Mar 30.
    Rare Disease Unit, I Dermatology Division, Istituto Dermopatico dell'Immacolata, IRCCS, Via Monti di Creta 104, 00167, Rome, Italy.
    Pityriasis rubra pilaris (PRP) is a rare inflammatory papulosquamous skin disease, often refractory to conventional therapies. The off-label use of biologics, such as anti-TNF, -IL-12/IL-23, -IL-17 agents, has been proven successful, in the last two decades, in PRP treatment. Our aim was to analyse the literature for the use of biologics in PRP treatment. Read More

    Recalcitrant psoriasiform dermatosis of the face: Is it related to pityriasis rubra pilaris?
    J Cutan Pathol 2018 Mar 31. Epub 2018 Mar 31.
    National Skin Centre, Singapore.
    Background: There are patients with recalcitrant psoriasiform plaques that do not fit into conventional categories of facial dermatoses. Our study aims to describe the clinicopathological characteristics of several patients with a unique presentation of persistent psoriasiform facial rashes.

    Methods: This retrospective cross-sectional study analyzed clinical and histological data of known cases of recalcitrant psoriasiform dermatosis of the face diagnosed at National Skin Centre, Singapore, over 10 years. Read More

    Fungal diseases in children and adolescents in a referral centre in Bogota, Colombia.
    Mycoses 2018 Mar 30. Epub 2018 Mar 30.
    Dermatology Resident, Fundación Universitaria Sanitas, Centro Dermatológico Federico Lleras Acosta, E.S.E, Bogotá, D.C, Colombia.
    A cross-sectional descriptive study was conducted at a dermatology referral centre in Bogotá to estimate the frequencies and aetiologies of mycoses in the population under 18 years of age attending the medical mycology laboratory over a 13-year period (2000-2012). A total of 1337 samples from 1221 patients were evaluated, involving direct examination and culture for 1279 samples, direct examination alone for 50 and culture alone for 8. During the study period, dermatophytosis was diagnosed via culture in 537 cases (40. Read More

    A study of skin disease spectrum occurring in Angola phototype V-VI population in Luanda.
    Int J Dermatol 2018 Mar 24. Epub 2018 Mar 24.
    Luanda Medical Center, Luanda, Angola.
    Background: Prevalence of skin diseases in Luanda (Angola) is unknown, and publications are barely found in the literature. We aim to describe, for the first time, the frequency of skin disease spectrum in phototype V-VI Angolan population in Luanda City.

    Methods: We included Fitzpatrick phototype V-VI Angolan patients who consulted the Dermatology Unit in Luanda Medical Center during a 1-year period. Read More

    Pityriasis rosea-like eruption associated with ondansetron use in pregnancy.
    Br J Clin Pharmacol 2018 May 9;84(5):1077-1080. Epub 2018 Mar 9.
    Department of Experimental Pathology, Immunology and Microbiology, Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
    A 30-year-old pregnant female presented with a 2-week history of pityriasis rosea-like eruption. The rash started 2 days after the patient had started taking ondansetron 8 mg for alleviation of moderate-to-severe nausea and vomiting of pregnancy. Physical examination revealed erythematous papulosquamous lesions characterized by annular scaly margins and a dusky centre over the arms, chest, abdomen, lower back and legs. Read More

    Malassezia species retrieved from skin with pityriasis versicolor, seborrheic dermatitis and skin free of lesions: a comparison of two sampling methods.
    Br J Dermatol 2018 Mar 5. Epub 2018 Mar 5.
    Division of Microbiology, Department of Pathology, Faculty of Medicine, University of Porto, Portugal.
    Malassezia are involved in the pathogenesis of different skin diseases including pityriasis versicolor (PV) and seborrheic dermatitis (SD), but these yeasts are also important inhabitants of the skin microbiome. Culture is not performed routinely, although it may be of value in doubtful cases to support the diagnosis; culture is crucial for identification tools such as matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). Culture is also critical to assess the number of organisms and viability and, eventually, to perform antifungal susceptibility tests. Read More

    Scabies Surrepticius: Scabies Masquerading as Pityriasis Rosea.
    Cureus 2017 Dec 19;9(12):e1961. Epub 2017 Dec 19.
    Department of Dermatology, University of California, San Diego.
    Scabies, a mite infestation caused by 'Sarcoptes scabiei', most commonly presents as pruritic linear burrows where the mite has invaded the skin. Scabies variant such as bullous, crusted, hidden, incognito, nodular and scalp-mimic the other conditions. In addition, atypical presentations of scabies can masquerade as dermatitis herpetiformis, ecchymosis, Langerhans cell histiocytosis, systemic lupus erythematosus, urticaria, and urticaria pigmentosa. Read More

    CARD14-associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris.
    J Am Acad Dermatol 2018 Mar 1. Epub 2018 Mar 1.
    Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut; Department of Genetics, Yale University School of Medicine, New Haven, Connecticut; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut. Electronic address:
    Background: Heterozygous mutations in caspase recruitment domain family member 14 gene (CARD14) have been shown to be associated with psoriasis and familial pityriasis rubra pilaris (PRP). Many subjects with CARD14 mutations display features of both disorders, which can result in diagnostic uncertainty. In addition, these eruptions are often recalcitrant to conventional psoriasis therapies such as methotrexate, oral retinoids, and tumor necrosis factor-α inhibitors. Read More

    Atypical presentations of pityriasis rosea: a reply.
    Dermatol Online J 2017 Aug 15;23(8). Epub 2017 Aug 15.
    Department of Dermatology, IRCCS AOU San Martino, Genoa, Italy.
    Pityriasis rosea (PR) may have atypical presentations as regards morphology and distribution of the lesions. Recently, several forms of PR considered atypical for the course of the disease have been described. Differently from the typical PR that resolves within 2-12 weeks, relapsing and persistent PR forms (lasting longer than 12 weeks) have been described in adults and children. Read More

    Erythrodermic Psoriasis in a Man with Monoclonal B-cell Lymphocytosis.
    Cureus 2017 Dec 11;9(12):e1936. Epub 2017 Dec 11.
    Department of Dermatology, University of California, San Diego.
    Erythroderma is characterized by erythema involving greater than 90% of the body surface area and may be caused by several etiologies, including erythrodermic psoriasis. Psoriasis is an autoimmune skin and systemic condition characterized by erythematous and scaly plaques. Monoclonal B-cell lymphocytosis is an asymptomatic hematological disorder diagnosed by elevated, small, clonal B-cell counts in the peripheral blood. Read More

    Pityriasis lichenoides-like drug reaction: A clinical histopathologic study of 10 cases.
    Dermatol Online J 2017 Nov 15;23(11). Epub 2017 Nov 15.
    Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York.
    Background: Lymphomatoid drug reactions can mimic endogenous T and B cell lymphoproliferative diseases.

    Objectives: We present a novel form of cutaneous drug reaction with features of pityriasis lichenoides (PL), a recognized form of T cell dyscrasia.

    Methods: Ten cases were studied where a cutaneous eruption exhibiting semblance to PL within a few weeks to months after starting a particular drug. Read More

    Geographic tonguelike presentation in a child with pityriasis rosea: Case report and review of oral manifestations of pityriasis rosea.
    Pediatr Dermatol 2018 Mar 13;35(2):e124-e127. Epub 2018 Feb 13.
    Division of Dermatology, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
    Oral lesions are rarely reported in patients with pityriasis rosea. We report a case of a 3-year-old boy with clinical evidence of generalized pityriasis rosea who developed asymptomatic oral lesions similar in appearance to geographic tongue. The generalized eruption and tongue lesions resolved simultaneously within 4 weeks. Read More

    Pigmentation Disorders: Diagnosis and Management.
    Am Fam Physician 2017 Dec;96(12):797-804
    Norton Audobon Hospital, Louisville, KY, USA.
    Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules. These conditions are generally benign but can be distressing to patients. Read More

    Autoinflammatory keratinization diseases: An emerging concept encompassing various inflammatory keratinization disorders of the skin.
    J Dermatol Sci 2018 Feb 1. Epub 2018 Feb 1.
    Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan.
    Classifying inflammatory skin diseases is challenging, especially for the expanding group of disorders triggered by genetic factors resulting in hyperactivated innate immunity that result in overlapping patterns of dermal and epidermal inflammation with hyperkeratosis. For such conditions, the umbrella term "autoinflammatory keratinization diseases" (AIKD) has been proposed. AIKD encompasses diseases with mixed pathomechanisms of autoinflammation and autoimmunity, and includes IL-36 receptor antagonist (IL-36Ra)-related pustulosis, CARD14-mediated pustular psoriasis, pityriasis rubra pilaris (PRP) type V, and familial keratosis lichenoides chronica (KLC). Read More

    [Prevalence of dermatomycoses in professional football players : A study based on data of German Bundesliga fitness check-ups (2013-2015) compared to data of the general population].
    Hautarzt 2018 Feb 7. Epub 2018 Feb 7.
    Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen (IVDP), Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistr. 52, 20246, Hamburg, Deutschland.
    Background: The prevention, early diagnosis and treatment of onychomycosis is of great importance for professional athletes to avoid physical limitations by complications. So far, there is only little data on the prevalence of dermatomycosis in professional athletes.

    Objectives: The aim of the study was to detect the prevalence of dermatomycosis in professional football players compared to the general population. Read More

    Incidence of diseases primarily affecting the skin by age group: population-based epidemiologic study in Olmsted County, Minnesota, and comparison with age-specific incidence rates worldwide.
    Int J Dermatol 2018 Jan 29. Epub 2018 Jan 29.
    Division of Clinical Dermatology, Mayo Clinic, Rochester, MN, USA.
    Understanding the effects of age on the epidemiology of diseases primarily affecting the skin is important to the practice of dermatology, both for proper allocation of resources and for optimal patient-centered care. To fully appreciate the effect that age may have on the population-based calculations of incidence of diseases primarily affecting the skin in Olmsted County, Minnesota, and worldwide, we performed a review of all relevant Rochester Epidemiology Project-published data and compared them to similar reports in the worldwide English literature. Using the Rochester Epidemiology Project, population-based epidemiologic studies have been performed to estimate the incidence of specific skin diseases over the past 50 years. Read More

    Pityriasis Rosea: Diagnosis and Treatment.
    Am Fam Physician 2018 Jan;97(1):38-44
    Emory University School of Medicine, Atlanta, GA, USA.
    Pityriasis rosea is a common self-limiting rash that usually starts with a herald patch on the trunk and progresses along the Langer lines to a generalized rash over the trunk and limbs. The diagnosis is based on clinical and physical examination findings. The herald patch is an erythematous lesion with an elevated border and depressed center. Read More

    Double-blind randomized placebo-controlled trial to evaluate the efficacy and safety of short-course low-dose oral prednisolone in pityriasis rosea.
    J Dermatolog Treat 2018 Feb 1:1-6. Epub 2018 Feb 1.
    g Skin-Aid Clinic , Gurugram , India.
    Purpose: To evaluate the efficacy and safety of short-course low-dose oral prednisolone in symptomatic pityriasis rosea (PR) of onset <5 days and compare it with placebo.

    Material And Methods: Placebo-controlled randomized double-blind study design with the treatment group receiving tapering doses of oral prednisolone over 2 weeks and the control group receiving a placebo. Outcome measures evaluated were subsidence of patient-perceived pruritus, improvement in rash quantified by a specific score, adverse effects and relapse at 12 weeks. Read More

    First case of superficial infection due (formerly ) in Iran: A review of the literature.
    Curr Med Mycol 2017 Jun;3(2):33-37
    Department of Medical Mycology and Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
    Background And Purpose: (formerly ) is a non-neoformans cryptococcal species rarely isolated as a human pathogen.

    Case Report: Herein, we present the case of a 26-year-old Iranian man with a superficial cutaneous lesion in the axilla. The initial treatment for pityriasis versicolor by clotrimazole was unsuccessful. Read More

    Possible role of plasmacytoid dendritic cells in pityriasis lichenoides.
    Clin Exp Dermatol 2018 Jan 19. Epub 2018 Jan 19.
    Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.
    Background: Plasmacytoid dendritic cells (pDCs) and their product, type I interferons (IFNs), have been implicated in the pathogenesis of several skin disorders characterized by an interface dermatitis (ID) pattern, such as lichen planus (LP). A type I IFN signature has previously been documented in pityriasis lichenoides (PL). Although pDCs are known to be the main source and most potent producers of local type I IFNs, their role in PL has not been investigated. Read More

    Methotrexate Treatment for Pityriasis Rubra Pilaris: A Case Series and Literature Review.
    Acta Derm Venereol 2018 Jan 16. Epub 2018 Jan 16.
    Department of Dermatology, Medical University of Graz, AT-8036 Graz, Austria.
    Treatment recommendations for pityriasis rubra pilaris (PRP) are based solely on case reports and small case series, as to-date no randomized controlled trials are available. We present here a case series of 3 patients and a literature review of 28 studies treating a total of 116 patients, with the aim of providing data regarding efficacy and safety of methotrexate in the treatment of PRP. Methotrexate was effective in our patients; the review showed an overall response rate of 65. Read More

    Pityriasis lichenoides: Long-term follow-up study.
    Pediatr Dermatol 2018 Mar 9;35(2):213-219. Epub 2018 Jan 9.
    Department of Dermatology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
    Background/objectives: Pityriasis lichenoides is an uncommon papulosquamous disorder of unknown etiology. The objective of this study was to review the clinical features and treatment responses of individuals with pityriasis lichenoides seen at a tertiary referral center.

    Methods: Seventy-five patients diagnosed with pityriasis lichenoides between 1997 and 2013 were reviewed, and 46 had long-term follow-up via telephone interviews. Read More

    Malassezia species in students from universities of Sabzevar, Northeastern Iran.
    J Mycol Med 2018 Mar 5;28(1):70-75. Epub 2018 Jan 5.
    Molecular cell research center, Sabzevar university of medical sciences, Sabzevar, Iran.
    Background: Malassezia species, usually part of normal human skin microbiota, may also cause cutaneous infections, mainly pityriasis versicolor (PV) which may rapidly spread in crowded communities, particularly in students' dormitories and sport leisure centers.

    Objective: Few studies have been conducted on PV in students in the Middle East. The present study was designed to determine prevalence of Malassezia species and related diseases in students from city of Sabzevar, Northeast Iran. Read More

    A Review on Pityriasis Rubra Pilaris.
    Am J Clin Dermatol 2018 Jan 4. Epub 2018 Jan 4.
    National Skin Centre, 1 Mandalay Rd, Singapore, 308205, Republic of Singapore.
    Pityriasis rubra pilaris (PRP) is an idiopathic, papulosquamous inflammatory dermatosis. It is characterized by hyperkeratotic follicular papules coalescing into orange-red scaly plaques, islands of sparing, and palmoplantar keratoderma. PRP can be subdivided into six clinical subtypes according to Griffiths' classification, based on age of onset, disease extent, prognosis, and other associated features. Read More

    Skin and coeliac disease, a lot to think about: a case series.
    BMJ Case Rep 2018 Jan 4;2018. Epub 2018 Jan 4.
    Pediatric Department, Hospital of Divino Espírito Santo of Ponta Delgada, Ponta Delgada - São Miguel, Azores, Portugal.
    Coeliac disease (CD) is an autoimmune disease, characterised by a permanent sensitivity to gluten. It is being progressively recognised as a multisystemic disease, with multiple extraintestinal manifestations. Skin conditions (eg, dermatitis herpetiformis) are an example of its manifestations; however, its underlying mechanisms are still not well understood. Read More

    Correction to: Antifungal activity of Myrtus communis against Malassezia sp. isolated from the skin of patients with pityriasis versicolor.
    Infection 2018 04;46(2):287
    Department of Biomedical Sciences, University of Sassari, V. le San Pietro 43/C, 07100, Sassari, Italy.
    The original version of this article unfortunately contained two mistakes in authors' names. Read More

    Lakartidningen 2017 Nov 21;114. Epub 2017 Nov 21.
    Karolinska Universitetssjukhuset Hudkliniken - Stockholm, Sweden Karolinska Universitetssjukhuset Hudkliniken - Stockholm, Sweden.
    Psoriasis in childhood and adolescence Psoriasis is a common inflammatory disease affecting 2-3% of the worldwide population. Onset in childhood and adolescence is not uncommon and around 30% of patients report onset before 20 years of age. Childhood psoriasis has been shown to differ in clinical presentation and in underlying genetics compared to adult psoriasis patients. Read More

    [Pityriasis rubra pilaris].
    Ann Dermatol Venereol 2018 Jan 28;145(1):50-59. Epub 2017 Dec 28.
    Service de dermatologie, hôpitaux universitaires de Genève (HUG), 1211 Genève, Suisse.
    Pityriasis rubra pilaris is a rare heterogeneous dermatosis associating three clinical signs to different degrees: follicular corneal papules, reddish-orange palmoplantar keratoderma and erythematosquamous lesions that may in some cases be very extensive, interspersed with patches of healthy skin. The aetiology is unclear, and in most cases, the trigger factors consist of trauma or infection, probably in subjects with an existing predisposition. In other cases, the condition is associated with immunological disorders or, in familial cases, genetic keratinisation abnormalities similar to ichthyosis. Read More

    A Fatal Case of Febrile Ulceronecrotic Mucha-Habermann Disease which Presenting as Toxic Epidermal Necrolysis.
    Indian J Dermatol 2017 Nov-Dec;62(6):675
    Department of Dermatology, Hangzhou Institute of Dermatology and Venereology, The Third People's Hospital of Hangzhou, Hangzhou, China.
    Febrile ulceronecrotic Mucha-Habermann disease (FUMHD), a severe form of pityriasis lichenoides et varioliformis acuta, is an inflammatory dermatosis of unknown etiology manifested by ulcerative and necrotic lesions accompanied by systemic manifestations. The mortality rate of FUMHD is about 15%. It is reported here a case of FUMHD presenting as toxic epidermal necrolysis that resulted in multiple organ failure and death. Read More

    Occult Hepatitis B Virus Infections (Often with Human Herpesvirus 7 Co-Infection) Detected in Patients: A Pilot Study.
    Indian J Dermatol 2017 Nov-Dec;62(6):598-605
    Infectious Diseases & Immunology Division, CSIR Indian Institute of Chemical Biology, Kolkata, West Bengal, India.
    Background: The etiopathogenesis of (PR), a papulo-squamous skin disease, remains elusive and hypothesized to be caused primarily by human herpesvirus (HHV) 6 or 7 or immune dysfunction.

    Aims: The recent increasing incidences of hepatitis B virus (HBV) infections, including asymptomatic occult HBV infections (OBIs), in a densely populated city in India, prompted us to investigate whether PR patients (from varied socioeconomic and immune status) harbor the underlying HBV infections. These cases were also investigated for HHV 6 and 7 infections. Read More

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