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J Dtsch Dermatol Ges 2018 Dec 6. Epub 2018 Dec 6.

Department of Dermatology, Venereology, and Allergology, University Medical Centre, Göttingen, Germany.

Pityriasis rubra pilaris (PRP) is a rare papulosquamous disorder. Treatment is challenging; the armamentarium consists of topical corticosteroids, phototherapy, classic systemic treatments such as retinoids or immunosuppressive drugs, and most recently biologicals. However, the relative effectiveness of therapies is unclear. Read More

J Dermatol 2018 Dec 3. Epub 2018 Dec 3.

Department of Dermatology, Kansai Medical University, Hirakata, Japan.

We report herein a case of a 72-year-old man with pityriasis rubra pilaris (PRP) that was refractory to conventional therapies. His skin lesions progressed to generalized erythroderma despite anti-interleukin (IL)-17A antibody therapy. Topical corticosteroids, emollients, systemic retinoid, methotrexate, cyclosporin and phototherapy yielded no therapeutic response. Read More

Indian Dermatol Online J 2018 Nov-Dec;9(6):474-476

Department of Dermatology and Venereology, Pramukhswami Medical College, Karamsad, Gujarat, India.

Indian Dermatol Online J 2018 Nov-Dec;9(6):414-417

Department of Dermatology, AIIMS, Raipur, India.

Background: Pityriasis rosea (PR) is a common, self-limiting dermatologic disorder. The information regarding the clinical profile of the disease in India is limited because of inadequate studies.

Materials And Methods: A retrospective, record-based study on the clinical presentation of PR was conducted in a tertiary care center based in Central India. Read More

Indian J Dermatol 2018 Nov-Dec;63(6):522-524

Department of Dermatology and Venereology, Pramukhswami Medical College, Karamsad, Gujarat, India. E-mail:

BMC Dermatol 2018 Dec 4;18(1):11. Epub 2018 Dec 4.

Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology laboratory, Mahosot Hospital, Vientiane, Laos.

Background: Skin diseases are common and often have an impact on an individual's health-related quality of life. In rural communities where access to healthcare may be limited and individuals rely on farming for food and income, the impact of skin diseases may be greater. The objectives for this study were to perform an assessment of skin disease prevalence in a rural village in Laos and assess the associated impact of any skin disease found using the Dermatology Life Quality Index (DLQI). Read More

Dermatol Pract Concept 2018 Oct 31;8(4):299-302. Epub 2018 Oct 31.

Department of Skin & VD, Patna Medical College and Hospital, Patna, Bihar, India.

Background: Diagnosing and differentiating pityriasis rubra pilaris (PRP) from other disorders can be a challenging task. Although histopathology remains the gold standard, it may not be feasible at times, especially in children. Being noninvasive, dermoscopy can be of great diagnostic importance in such a scenario. Read More

G Ital Dermatol Venereol 2018 Nov 9. Epub 2018 Nov 9.

Department of Dermatology, University of Naples Federico II, Naples, Italy.

Front Immunol 2018 16;9:2239. Epub 2018 Oct 16.

Department of Dermatology, University Hospital Zürich, Zürich, Switzerland.

The CARD: BCL10: MALT1 (CBM) complex is an essential signaling node for maintaining both innate and adaptive immune responses. CBM complex components have gained considerable interest due to the dramatic effects of associated mutations in causing severe lymphomas, immunodeficiencies, carcinomas and inflammatory disease. While MALT1 and BCL10 are ubiquitous proteins, the CARD-containing proteins differ in their tissue expression. Read More

JAMA Dermatol 2018 Oct 31. Epub 2018 Oct 31.

JAAD Case Rep 2018 Oct 10;4(9):944-946. Epub 2018 Oct 10.

Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.

Pan Afr Med J 2018 29;30:78. Epub 2018 May 29.

Hôpital Civil Tétouan, Tétouan, Maroc.

Epidermodysplasia verruciformis, also known as Lewandowsky-Lutz syndrome or tree man disease is a rare genetic skin disorder. It is characterized by abnormal susceptibility of the skin coating to human papillomaviruses (HPVs). It commonly affects people between the ages of 4 and 8, most often before the age of 20 years but it may exceptionally occur later. Read More

J Mycol Med 2018 Dec 16;28(4):590-593. Epub 2018 Oct 16.

Laboratoire de Parasitologie-Mycologie, CHU Aristide Le Dantec, BP 5005, Dakar, Senegal; Service de Parasitologie-Mycologie, Faculté de Médecine, de Pharmacie et d'Odontologie, Université Cheikh Anta Diop, BP 16477, Dakar, Senegal.

Pityriasis versicolor (PV) is a superficial mycosis caused by yeast of the genus Malassezia. The most common isolated Malassezia species in PV lesions differ among M. furfur, M. Read More

Actas Dermosifiliogr 2018 Nov 10;109(9):777-790. Epub 2018 Oct 10.

Departamento de Dermatología, Universidad Autónoma de Nuevo León, Hospital Universitario «Dr. José E. González» y Facultad de Medicina, Monterrey, México. Electronic address:

Erythroderma is an inflammatory skin syndrome that involves desquamation and erythema of more than 90% of the body surface area. It represents a final clinical endpoint for many adult dermatological conditions. The most frequent cause of erythroderma is psoriasis followed by eczematous conditions, drug-induced reactions, pityriasis rubra pilaris and cutaneous T-cell lymphomas. Read More

J Am Acad Dermatol 2018 Oct 1. Epub 2018 Oct 1.

Department of Dermatology, Preventive Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL; Northwestern Medicine Multidisciplinary Eczema Center, Chicago, IL. Electronic address:

Background: Previous studies found conflicting results about the commonality of different atopic dermatitis (AD) signs and symptoms.

Objective: To determine the prevalences of AD characteristics and differences by region and age.

Methods: A systematic review was performed of all published studies in MEDLINE, EMBASE, SCOPUS, LILACS, Cochrane, China National Knowledge Infrastructure, Taiwan electronic periodical services and CiNii that analyzed the proportion of AD characteristics. Read More

Dermatol Ther 2018 Nov 3;31(6):e12734. Epub 2018 Oct 3.

Department of Dermatology, Universidad Autónoma de Nuevo León, Hospital Universitario "Dr. José Eleuterio González" y Facultad de Medicina, Monterrey, Nuevo León, Mexico.

Photodermatol Photoimmunol Photomed 2018 Sep 29. Epub 2018 Sep 29.

Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Graz, Austria.

Background: Medical phototherapy can lead to the manifestation of polymorphic light eruption (PLE), though little is known about the frequency of such events.

Aims: The aim of this Austrian single center study was to retrospectively investigate over a 4-year time period the frequency of PLE in patients prone to the condition and patients with other diseases under phototherapy (mainly narrow-band and broad-band UVB).

Materials And Methods: The data for analysis were obtained from the electronic health and patient record database and patient files of the Photodermatology Unit, Department of Dermatology, Medical University of Graz, Austria. Read More

J Dermatol 2018 Nov 28;45(11):1278-1282. Epub 2018 Sep 28.

Division of Microbiology, Department of Pathology, Faculty of Medicine, University of Porto, Porto, Portugal.

Malassezia are lipophilic and commensal yeasts capable of inducing skin disease among susceptible hosts. However, severely immunocompromised patients and preterm infants admitted to intensive care units are particularly at risk of developing Malassezia systemic infections. Patients often have central venous catheters which are usually the portal of entry for colonization and infection. Read More

Hautarzt 2018 Oct;69(Suppl 1):22-24

Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstr. 9-11, 80337, München, Deutschland.

Cureus 2018 Jul 20;10(7):e3017. Epub 2018 Jul 20.

Department of Microbiology, Prathima Institute of Medical Sciences, Karimnagar, IND.

Tinea faciei (TF) is a common dermatomicrobiological condition caused by dermatophytes involving the skin of the face but not the mustache and beard (Tinea barbae). It poses a diagnostic dilemma with its atypical clinical presentation. Pityriasis folliculorum (PF) is a dermatological condition that results in rosacea-like skin eruptions. Read More

JAAD Case Rep 2018 Sep 14;4(8):800-801. Epub 2018 Sep 14.

DISSAL Department of Dermatology, Policlinico San Martino, Genoa, Italy.

JAAD Case Rep 2018 Sep 14;4(8):774-776. Epub 2018 Sep 14.

Creighton University School of Medicine, Omaha, Nebraska.

J Am Acad Dermatol 2018 Sep 17. Epub 2018 Sep 17.

Department of Dermatology and Medicine, University of Florida College of Medicine, Gainesville, FL.

Acquired hypopigmented skin changes are commonly encountered by dermatologists. Although hypopigmentation is often asymptomatic and benign, occasional serious and disabling conditions present with cutaneous hypopigmentation. A thorough history and physical examination, centered on disease distribution and morphological findings, can aid in delineating the causes of acquired hypopigmented disorders. Read More

Dermatol Ther 2018 09 19;31(5):e12694. Epub 2018 Sep 19.

Anatomopathology, Department of Surgical Science, University of Cagliari, Cagliari, Italy.

G Ital Dermatol Venereol 2018 Sep 18. Epub 2018 Sep 18.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, I.R.C.C.S. Foundation, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

Clin Dermatol 2018 Sep - Oct;36(5):631-640. Epub 2018 Jun 1.

Department of Dermatology, Mt Sinai West, Icahn School of Medicine at Mt Sinai, New York, NY. Electronic address:

Atopic dermatitis is a common chronic pruritic inflammatory skin disorder, characterized by an abnormal skin barrier, immune dysfunction, and an altered skin microbiome. Atopic dermatitis may be seen in conjunction with a variety of other skin disorders due to the complex pathogenesis of atopic dermatitis, involving genetic and environmental factors that are associated with immune dysfunction, barrier defects, and altered skin microbiomes. Skin disorders associated with atopic dermatitis include diseases sharing similar genetic origins like ichthyosis vulgaris, infectious diseases such as impetigo, and eczema herpeticum, in addition to the cutaneous autoimmune diseases, alopecia areata, and vitiligo. Read More

Am Fam Physician 2018 Sep;98(5):283-291

Thomas Jefferson University Hospital, Philadelphia, PA, USA.

Annular lesions can present in a variety of diseases. Knowledge of the physical appearance and history of presentation of these skin findings can help in the diagnosis. A pruritic, annular, erythematous patch that grows centrifugally should prompt evaluation for tinea corporis. Read More

Skinmed 2018 1;16(4):255-257. Epub 2018 Jul 1.

Rutgers - New Jersey Medical School, Newark, NJ, Department of Biological Sciences, New York Institute of Technology, Old Westbury, New York.

J Cutan Pathol 2018 Sep 10. Epub 2018 Sep 10.

Department of Dermatology, University of California San Francisco, San Francisco, California.

Background: Acantholysis can be seen in multiple skin diseases. Adnexal acantholysis has been regarded as a feature distinguishing pemphigus vulgaris (PV) from acantholytic conditions.

Methods: A retrospective review of the histopathologic features of diseases with acantholysis including PV, pemphigus foliaceus (PF), Hailey-Hailey disease (HHD), Darier disease (DD), Grover disease, and pityriasis rubra pilaris (PRP) was performed. Read More

Australas J Dermatol 2018 Sep 9. Epub 2018 Sep 9.

Department of Dermatology, Cutaneous Lymphoma Clinic, "Andreas Sygros" Hospital, University of Athens Medical School, Athens, Greece.

An Bras Dermatol 2018 Sep-Oct;93(5):686-695

Postgraduate Clinical Programs, Universidad del Valle, Cali, Colombia.

Background: There is a lack of evidence to support acyclovir administration in pityriasis rosea.

Objective: To determine the efficacy of acyclovir in patients with typical pityriasis rosea.

Methods: A systematic review and meta-analysis of experimental studies was performed in MEDLINE, SCOPUS, EMBASE and others, from January 1990 to October 2016 on acyclovir for pityriasis rosea. Read More

Ann Dermatol Venereol 2018 Oct 22;145(10):623-632. Epub 2018 Aug 22.

Laboratoire de mycologie, Hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75475 Paris cedex 10, France. Electronic address:

Dermatomycoses are dermatological infections very commonly encountered in private dermatological practice since they affect up to one third of the population. However, the symptoms are very often shared by other skin infections and disorders and may be highly atypical. It is thus impossible to make a diagnosis with any certainty on clinical grounds alone. Read More

Dermatol Ther 2018 09 22;31(5):e12681. Epub 2018 Aug 22.

Department of Pathology, School of Medicine, Gaziosmanpasa University, Tokat, Turkey.

Pityriasis lichenoides (PL) is a spectrum of inflammatory skin diseases which include PL et varioliformis acuta (PLEVA) and PL chronica (PLC) as two ends of the disease and rarely both entities can coexist on the same patient. Treatment options are based on case series-reports, and anecdotes, and include topical corticosteroids, topical immunomodulators, systemic antibiotics (tetracycline, erythromycin), and phototherapy. Herein, we report a 13-year-old boy, exhibiting mixed manifestations of PLEVA and PLC lesions concurrently, with a rapid and dramatic response to azithromycin monotherapy. Read More

Clin Exp Dermatol 2019 01 20;44(1):73-75. Epub 2018 Aug 20.

Dermatology Unit, Department of Physiopathology and Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Pace 9, 20122, Milan, Italy.

J Dtsch Dermatol Ges 2018 Aug;16(8):1022-1025

Department of Dermatology, Hospital Universitario 12 de Octubre, I+12 Research Institute, Madrid, Spain.

Indian J Dermatol Venereol Leprol 2018 Aug 14. Epub 2018 Aug 14.

Rita Skin Foundation, Kolkata, West Bengal, India.

JAAD Case Rep 2018 Aug 9;4(7):669-671. Epub 2018 Aug 9.

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.

J Dermatolog Treat 2018 Sep 4:1-6. Epub 2018 Sep 4.

a Department of Dermatology , Taipei Medical University Hospital , Taipei , Taiwan.

Background: Acyclovir has been reported as a potential therapy for pityriasis rosea (PR) in several clinical trials on the basis of evidence of the involvement of human herpes viruses 6 and 7.

Objective: We evaluated the efficacy of acyclovir for abating PR skin lesions within a fixed period.

Methods: We searched 4 databases for clinical trials that used oral acyclovir to treat PR and performed systematic review and meta-analysis to determine oral acyclovir's effect on skin lesions on the 14th day after commencing treatment. Read More

Mycoses 2018 Aug 14. Epub 2018 Aug 14.

Department of Medical Mycology & Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Dihydroxyacid dehydratase (DHAD) is a key enzyme in biosynthetic pathway of isoleucine and valine. This pathway is absent in human but exists in various organisms such as fungi. Using RNA-seq analysis in this study, we identified MGL_3741gene which encodes DHAD protein in Malassezia globosa (M. Read More

Trop Doct 2018 Oct 12;48(4):348-349. Epub 2018 Aug 12.

4 Professor, Department of Pediatrics, Lady Hardinge Medical College and associated Kalawati Saran Children Hospital, New Delhi, India.

A seven-year-old boy with nephrotic syndrome presented with a frequent rash along with relapse of nephrotic syndrome. Clinical and histological features were suggestive of pityriasis lichenoides et varioliformis acuta (PLEVA). Treatment of the condition with doxycycline led to the cure of the lesions as well as the relapses. Read More

Am J Dermatopathol 2018 Jul 24. Epub 2018 Jul 24.

Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center and Geisel School of Medicine, Lebanon, NH.

Pityriasis rubra pilaris (PRP) is a rare, chronic, heterogeneous, papulosquamous inflammatory dermatosis of unknown etiology. Although erythematous scaly patches characterize the classic presentation of PRP, a broad range of clinical presentations has been reported. Histologically, PRP is characterized by psoriasiform acanthosis with alternating orthokeratosis and parakeratosis and rarely small acantholytic foci. Read More

Front Immunol 2018 3;9:1564. Epub 2018 Jul 3.

MTA-SZTE Dermatological Research Group, University of Szeged, Szeged, Hungary.

Pityriasis rubra pilaris (PRP) is a rare papulosquamous skin disorder, which is phenotypically related to psoriasis. Some familial PRP cases show autosomal dominant inheritance due to mutations leading to increased nuclear factor κB (NFκB) activation. Moreover, polymorphisms have also been implicated in sporadic PRP. Read More

JAAD Case Rep 2018 Jun 7;4(5):500-505. Epub 2018 May 7.

Department of Dermatology, Liverpool Hospital, Sydney, Australia.

Med J Malaysia 2018 Jun;73(3):125-130

Hospital Kuala Lumpur, Department of Dermatology, Kuala Lumpur, Malaysia.

Introduction: Ultraviolet phototherapies are important treatment modalities for a wide range of dermatological conditions. We aim to describe the utilization of phototherapy in the Department of Dermatology Hospital Kuala Lumpur.

Methods: This is a 5-year retrospective audit on patients who underwent phototherapy between 2011 and 2015. Read More

J Eur Acad Dermatol Venereol 2018 Jul 1. Epub 2018 Jul 1.

Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Service de Biostatistique et Informatique Médicale (SBIM), Free University of Brussels (ULB), Brussels, Belgium.

J Dtsch Dermatol Ges 2018 Aug 27;16(8):1022-1025. Epub 2018 Jun 27.

Department of Dermatology, Hospital Universitario 12 de Octubre, I+12 Research Institute, Madrid, Spain.

Front Microbiol 2018 12;9:1222. Epub 2018 Jun 12.

Department of Biomedicine, University Hospital of Basel, University of Basel, Basel, Switzerland.

Epidermodysplasia verruciformis (EV) is an autosomal recessive skin disorder with a phenotype conditional on human beta-papillomavirus (beta-HPV) infection. Such infections are common and asymptomatic in the general population, but in individuals with EV, they lead to the development of plane wart-like and red or brownish papules or pityriasis versicolor-like skin lesions, from childhood onwards. Most patients develop non-melanoma skin cancer (NMSC), mostly on areas of UV-exposed skin, from the twenties or thirties onwards. Read More