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    1177 results match your criteria Pituitary Apoplexy

    1 OF 24

    Multidisciplinary Management of Pituitary Apoplexy.
    Int J Endocrinol 2016 15;2016:7951536. Epub 2016 Dec 15.
    Unit of Endocrinology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
    Pituitary apoplexy is a rare clinical syndrome due to ischemic or haemorrhagic necrosis of the pituitary gland which complicates 2-12% of pituitary tumours, especially nonfunctioning adenomas. In many cases, it results in severe neurological, ophthalmological, and endocrinological consequences and may require prompt surgical decompression. Pituitary apoplexy represents a rare medical emergency that necessitates a multidisciplinary approach. Read More

    Macroprolactinomas and Nonfunctioning Pituitary Adenomas and Pregnancy Outcomes.
    Obstet Gynecol 2017 Jan;129(1):185-194
    Royal Hampshire County Hospital, Winchester, Hampshire, the Division of Women's Health, King's College London and Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare National Health Service Trust, London, the National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, and the Regional Centre for Endocrinology and Diabetes, Royal Victoria Hospital, Belfast, Northern Ireland, United Kingdom.
    Objective: To examine the monitoring, management, and outcomes of pituitary tumors in pregnancy.

    Methods: A national, prospective, observational, population-based case series study was conducted in all U.K. Read More

    Imaging of the Sella and Parasellar Region.
    Radiol Clin North Am 2017 Jan;55(1):83-101
    Division of Neuroradiology, Department of Radiology, Keck School of Medicine, University of Southern California, 1200 North State Street, Room 3740A, Los Angeles, CA 90033, USA.
    The sella and parasellar region, found between the anterior and central skull base, represents the central aspect of the skull base. Given the location of the pituitary gland in this location, small lesions in this location may have major physiologic effects on the human body. This article reviews the anatomy, development, and pathologic processes that may involve this region. Read More

    Spontaneous Involution of Rathke's Cleft Cysts without Visual Symptoms.
    Brain Tumor Res Treat 2016 Oct 31;4(2):58-62. Epub 2016 Oct 31.
    Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea.; Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
    Background: There have been various reports in the literature regarding the conservative management of pituitary apoplexy, pituitary incidentalomas and Rathke cleft cysts (RCCs). However, to the best of our knowledge, spontaneous involution of cystic sellar mass has rarely been reported. We report 14 cases of cystic sellar masses with spontaneous involution. Read More

    Prolactinoma and pregnancy - a series of cases including pituitary apoplexy.
    J Obstet Gynaecol 2016 Nov 21:1-4. Epub 2016 Nov 21.
    a Centro Hospitalar do Porto - Centro Materno Infantil do Norte , Porto , Portugal.
    The objective of this article is to evaluate the impact of pregnancy in women with prolactinoma, the possible consequences of therapy maintenance/discontinuation during pregnancy and to assess the type of delivery and maternal-foetal obstetrical outcome. A retrospective study of all pregnant women with prolactinoma in our Centre between 2006 and 2014 was made. We had 35 cases of pregnant women with prolactinoma, two of which had an episode of pituitary apoplexy during the second trimester. Read More

    Pituitary apoplexy masquerading as functional decline in an older person.
    Age Ageing 2016 Nov 3. Epub 2016 Nov 3.
    Department of Medicine, National University Hospital, Singapore 119074, Singapore.
    We report the case of an older lady who was admitted to a tertiary teaching hospital with sub-acute functional decline of two months' duration, which was initially attributed to a concomitant urinary tract infection. Further investigations, however, revealed the diagnosis of pituitary apoplexy with central hypocortisolism. Subsequent treatment with physiological doses of steroids improved patient's function and overall well-being. Read More

    Complex effects of apoplexy secondary to pituitary adenoma.
    Rev Neurosci 2017 Jan;28(1):59-64
    Pituitary adenoma apoplexy is a well-known clinical syndrome induced by insulin infusion, cardiac surgery, trauma, and hypothalamic releasing factors. Pituitary apoplexy can cause secondary cerebral infarct and internal carotid artery occlusion. With blockade of tumor perfusion, apoplexy triggers a sudden onset of headache, visual impairment, cranial nerve palsy, disturbances of consciousness, eyelid ptosis, and hemiparesis. Read More

    Rathke Cleft Cyst with Evidence of Rupture into Subarachnoid Space.
    World Neurosurg 2017 Jan 21;97:752.e1-752.e3. Epub 2016 Oct 21.
    Department of Neurosurgery, Nara Medical University, Kashihara, Nara, Japan.
    Background: A Rathke cleft cyst (RCC) with nonhemorrhagic rupture mimicking pituitary apoplexy has been reported rarely.

    Case Description: A 52-year-old woman, previously diagnosed with asymptomatic RCC, came to us with a severe headache, along with visual dysfunction and symptoms of pituitary insufficiency. Fluid-attenuated inversion recovery magnetic resonance imaging demonstrated diffuse hyperintensity in the cerebral cisterns, whereas watery clear cerebrospinal fluid was obtained by lumbar puncture. Read More

    Surgical versus non-surgical treatment for pituitary apoplexy: A systematic review and meta-analysis.
    J Neurol Sci 2016 Nov 23;370:258-262. Epub 2016 Sep 23.
    Department of Neurosurgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China. Electronic address:
    Background: Pituitary apoplexy is a rare disease caused by a sudden hemorrhage into or infarction of the pituitary gland. Its optimal management remains controversial. The aim of this study was to compare the outcomes of surgical and non-surgical treatments for pituitary apoplexy. Read More

    [Cerebral infarction after pituitary apoplexy: Description of a case and review of the literature].
    Neurocirugia (Astur) 2016 Nov - Dec;27(6):310-314. Epub 2016 Jun 2.
    Servicio de Neurocirugía, Hospital Clínico de Santiago de Compostela, Santiago de Compostela, España.
    Pituitary apoplexy is usually the result of hemorrhagic infarction in a pituitary adenoma. The clinical presentation varies widely and includes asymptomatic cases, classical pituitary apoplexy and even sudden death. Cerebral ischemia due to pituitary apoplexy is very rare. Read More

    Pituitary Apoplexy Mimicking Bacterial Meningitis with Intracranial Hypertension.
    World Neurosurg 2017 Jan 15;97:748.e3-748.e5. Epub 2016 Oct 15.
    Department of Neuroradiology, APHP, Pitié-Salpêtrière Hospital, Paris, France; Sorbonne Universités, Pierre and Marie Curie Faculty of Medicine, Paris, France.
    Case Description: A 29-year-old patient experienced a violent headache during bodybuilding exercises. Brain magnetic resonance imaging revealed diffuse meningitis and a 38-mm necrotic pituitary adenoma. Meningoencephalitis was suspected but was ruled out by lumbar puncture. Read More

    Acute vision loss in post-partum period as presenting symptom of HIV-associated cryptococcal meningitis-an unusual case report.
    BMC Infect Dis 2016 Oct 19;16(1):582. Epub 2016 Oct 19.
    Department of Neurology, King George Medical University, Lucknow, PIN-226003, Uttar Pradesh, India.
    Background: Acute vision loss in the post-partum period can occur due to many reasons. Eclampsia, posterior reversible encephalopathy syndrome (PRES), pituitary apoplexy, and central serous retinopathy are some of the important causes. Cryptococcal meningitis as a cause of acute vision loss in the post-partum period has not been mentioned in literature. Read More

    A pediatric case of pituitary macroadenoma presenting with pituitary apoplexy and cranial nerve involvement: case report.
    Turk Pediatri Ars 2016 Sep 1;51(3):162-165. Epub 2016 Sep 1.
    Department of Neurosurgery, Bülent Ecevit University School of Medicine, Zonguldak, Turkey.
    Pituitary adenomas usually arise from the anterior lobe of the pituitary gland and are manifested with hormonal disorders or mass effect. Mass effect usually occurs in nonfunctional tumors. Pituitary adenomas may be manifested with visual field defects or rarely in the form of total oculomotor palsy. Read More

    Unusual Complication of Pituitary Macroadenoma: A Case Report and Review.
    Am J Case Rep 2016 Oct 6;17:707-711. Epub 2016 Oct 6.
    Department of Clinical Imaging, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
    BACKGROUND Pituitary macroadenoma is a common benign tumor that usually presents with visual field defects or hormonal abnormalities. Cerebral infarction can be a complication of a large pituitary adenoma. We report a rare case of bilateral anterior cerebral arteries infarcts by a large pituitary macroadenoma with apoplexy. Read More

    Approach to the management of rare clinical presentations of macroprolactinomas in reproductive-aged women.
    Case Rep Womens Health 2015 Oct 24;8:9-12. Epub 2015 Sep 24.
    Division of Endocrinology, Diabetes, Metabolism, and Nutrition, 200 First Street SW, Mayo Clinic, Rochester, MN, 55905, United States.
    Objective: To describe 2 cases of macroprolactinomas with atypical presentation in women desiring pregnancy that illustrate important considerations in the management approach for macroprolactinomas in reproductive-aged women.

    Patients: Case 1 was a 26-year-old woman referred to our institution for possible tumor resection after pituitary apoplexy during her first pregnancy. Instead, she underwent treatment with cabergoline for a year with goals of normalization of prolactin and decrease in tumor size to <1 cm before trying to conceive. Read More

    Time Course of Symptomatic Recovery After Endoscopic Transsphenoidal Surgery for Pituitary Adenoma Apoplexy in the Modern Era.
    World Neurosurg 2016 Dec 20;96:434-439. Epub 2016 Sep 20.
    Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
    Background: Pituitary tumor apoplexy can result from either hemorrhagic or infarctive expansion of pituitary adenomas, and the related mass effect can result in compression of critical neurovascular structures. The time course of recovery of visual field deficits, headaches, ophthalmoparesis, and pituitary dysfunction after endoscopic transsphenoidal surgery has not been well established.

    Methods: Medical records were retrospectively reviewed for all patients who underwent endoscopic transsphenoidal surgery for pituitary tumor apoplexy from April 2008 to November 2014. Read More

    Turk Neurosurg 2016 Feb 5. Epub 2016 Feb 5.
    Bulent Ecevit University, Faculty of Medicine.
    Pituitary apoplexy is a medical condition that needs urgent diagnosis and treatment. It may occur spontaneously or may be precipitated by a variety of reasons including dynamic endocrine tests. Although pituitary apoplexy is usually seen in non-functional pituitary adenoma, it can also be seen in ACTH secreting macroadenomas. Read More

    Pituitary Apoplexy After Initial Leuprolide Injection.
    World Neurosurg 2016 Nov 29;95:616.e7-616.e9. Epub 2016 Aug 29.
    Department of Medical Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA; Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA.
    Background: Pituitary apoplexy is a rare complication of the initial administration of leuprolide acetate.

    Case Description: We present the case of a 63-year-old man who experienced headache, blurred vision, and loss of consciousness after initial leuprolide treatment for prostate carcinoma. Neuroimaging showed pituitary hemorrhage. Read More

    A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism.
    Arch Endocrinol Metab 2016 Aug;60(4):374-90
    Serviço de Endocrinologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro (HUCFF-UFRJ), Rio de Janeiro, RJ, Brasil.
    Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumors after prolactinomas. The absence of clinical symptoms of hormonal hypersecretion can contribute to the late diagnosis of the disease. Thus, the majority of patients seek medical attention for signs and symptoms resulting from mass effect, such as neuro-ophthalmologic symptoms and hypopituitarism. Read More

    Pituitary tuberculoma: A consideration in the differential diagnosis in a patient manifesting with pituitary apoplexy-like syndrome.
    IDCases 2016 29;5:63-6. Epub 2016 Jul 29.
    Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
    Pituitary tuberculoma is extremely rare, even in endemic regions of tuberculosis and much less frequently as a presentation of pituitary apoplexy. We describe a 25-year-old female presented with sudden onset of headache and vision loss of left eye which mimicking symptoms of pituitary apoplexy. MRI of the pituitary gland showed a rim-enhancing lesion at the intrasellar region extending into the suprasellar area, but absence of posterior bright spot with enhancement of the pituitary stalk. Read More

    Pituitary apoplexy in pregnancy: A case series and literature review.
    Obstet Med 2015 Dec 22;8(4):177-83. Epub 2015 Sep 22.
    Endocrinology Division, Department of Medicine, Centre de Recherche du Centre hospitalier de l'Université de Montréal (CR-CHUM), Montreal, QC, Canada.
    Background: Severe headache during pregnancy is a challenging condition that may rarely imply endocrine disturbances. Rapid recognition of pituitary apoplexy is needed to improve pregnancy outcome.

    Objective: To review and compare maternal and fetal outcomes after pituitary apoplexy. Read More

    Subarachnoid hemorrhage caused by an undifferentiated sarcoma of the sellar region.
    Surg Neurol Int 2016 7;7(Suppl 16):S459-62. Epub 2016 Jul 7.
    Department of Diagnostic Pathology, Fujita Health University Hospital, Toyoake, Japan.
    Background: It is rare for patients with pituitary apoplexy to exhibit concomitant subarachnoid hemorrhage (SAH). Only a handful of patients with pituitary apoplexy have developed such hemorrhagic complications, and histopathological examination revealed pituitary adenoma as the cause of SAH.

    Case Report: A previously healthy 35-year-old woman was brought to our institution after complaining of severe headache and left monocular blindness. Read More

    Primary immune thrombocytopenia accompanied by pituitary apoplexy.
    Rinsho Ketsueki 2016 Jul;57(7):877-80
    Department of Hematology and Oncology, Kumamoto City Hospital.
    An 83-year-old woman was admitted to our hospital with a severe headache and purpura. She had previously been diagnosed with idiopathic thrombocytopenia purpura (ITP) and achieved complete remission with steroid therapy. Steroid therapy had been completed one week prior to the current admission. Read More

    Ischemic pituitary adenoma apoplexy-Clinical appearance and prognosis after surgical intervention.
    Clin Neurol Neurosurg 2016 Sep 7;148:142-6. Epub 2016 Jul 7.
    Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, Japan.
    Background: Several retrospective investigations have recommended more passive surgical indications for intratumoral hemorrhage of pituitary adenomas due to probable spontaneous resolution. However, no definitive analyses have compared pituitary adenomas with hemorrhagic apoplexy and intratumoral hemorrhage without evident apoplectic symptoms or pituitary adenoma infarction.

    Methods: This study retrospectively identified 43 patients with symptomatic pituitary apoplexy among 1067 patients with pituitary adenomas initially treated by surgery at a single institute between April 2005 and May 2015, with 27 cases of hemorrhagic (2. Read More

    Neuro-Ophthalmology Cases for the Neurologist.
    Neurol Clin 2016 Aug;34(3):611-29
    Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, 6560 Fannin Street, Scurlock 450, Houston, TX 77030, USA; Department of Ophthalmology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA; Department of Ophthalmology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Ophthalmology, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Department of Neurology, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Department of Neurosurgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Section of Ophthalmology, UT MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Electronic address:
    Neurologists should be aware of specific urgent and emergent neuro-ophthalmic conditions, including giant cell arteritis, arterial dissection, intracranial aneurysm, pituitary apoplexy, and invasive sino-orbital fungal infection (eg, mucormycosis). Early recognition and treatment can greatly impact patient morbidity and mortality, including the preservation of vision and life. Neurologists should be cognizant of the key and differentiating clinical and radiographic features for these presentations. Read More

    Third, Fourth, and Sixth Cranial Nerve Palsies in Pituitary Apoplexy.
    World Neurosurg 2016 Oct 17;94:447-452. Epub 2016 Jul 17.
    Department of Ophthalmology, Emory University, Atlanta, Georgia, USA; Department of Neurology, Emory University, Atlanta, Georgia, USA; Department of Epidemiology, Emory University, Atlanta, Georgia, USA. Electronic address:
    Background: Pituitary apoplexy (PA) often presents with acute headache and neuro-ophthalmic manifestations, including ocular motility dysfunction (OMD) from cranial nerve palsies (CNPs). Our goal was to describe the epidemiology and outcomes of OMD in a large, single-center series of patients with PA.

    Methods: We conducted a retrospective chart review of all patients with PA seen in our pituitary center between January 1995 and December 2012. Read More

    A primer on pituitary injury for the obstetrician gynecologist: Simmond's disease, Sheehan's Syndrome, traumatic injury, Dahan's Syndrome, pituitary apoplexy and lymphocytic hypophysitis.
    Minerva Ginecol 2017 Apr 13;69(2):190-194. Epub 2016 Jul 13.
    McGill Reproductive Center, McGill University, Royal Victoria Hospital, Montreal, Canada.
    The pituitary gland plays a critical role in reproduction. In response to the hypothalamus the anterior pituitary secretes prolactin, thyroid-stimulating hormone, adreno-corticotropic hormone, follicle-stimulating hormone, luteinizing hormone and growth hormone. Dysregulation in these hormones often lead to reproductive failure. Read More

    Ventriculitis from a pituitary prolactinoma: bacterial or chemical?
    Br J Neurosurg 2016 Jul 11:1-2. Epub 2016 Jul 11.
    a Department of Neurosurgery , Royal Victoria Hospital , Newcastle upon Tyne , UK ;
    We report the case of a 70-year-old man presenting with pituitary apoplexy from a macroprolactinoma and ventriculitis. It was not possible to distinguish a bacterial or chemical origin, on the basis of his clinical presentation, laboratory studies and imaging, highlighting the importance of prompt imaging and attainment of CSF cultures, in making the diagnosis. Read More

    Surgical management of acromegaly: Long term functional outcome analysis and assessment of recurrent/residual disease.
    Asian J Neurosurg 2016 Jul-Sep;11(3):261-7
    Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
    Context: Functional growth hormone producing adenomas have long-term deleterious effects on the visual apparatus, the cardiovascular and musculoskeletal systems, and often predispose to malignancies. Since persistence of acromegaly affects outcome and quality of life, therapeutic interventions become mandatory.

    Aim: This study represents an analysis of long-term clinical and endocrinal outcome of 115 patients of acromegaly after surgical management. Read More

    Pituitary Apoplexy Associated with Carotid Compression and a Large Ischemic Penumbra.
    World Neurosurg 2016 Aug 16;92:581.e7-581.e13. Epub 2016 Jun 16.
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA.
    Background: Pituitary apoplexy is an acute clinical syndrome caused by pituitary gland hemorrhage or infarction. Rarely, this clinical syndrome is associated with cerebral infarction secondary to compression of an internal carotid artery. We report an unusual case of pituitary apoplexy associated with a cerebral infarct with a large ischemic penumbra. Read More

    How should we interrogate the hypothalamic-pituitary-adrenal axis in patients with suspected hypopituitarism?
    BMC Endocr Disord 2016 Jun 17;16(1):36. Epub 2016 Jun 17.
    Division of Endocrinology, Beaumont Hospital, Dublin, Ireland.
    Hypopituitarism is deficiency of one or more pituitary hormones, of which adrenocorticotrophic hormone (ACTH) deficiency is the most serious and potentially life-threatening. It may occur in isolation or, more commonly as part of more widespread pituitary failure. Diagnosis requires demonstration of subnormal cortisol rise in response to stimulation with hypoglycemia, glucagon, ACTH(1-24) or in the setting of acute illness. Read More

    Gonadotropin-releasing hormone agonist-induced pituitary apoplexy.
    Endocrinol Diabetes Metab Case Rep 2016 8;2016:160021. Epub 2016 Jun 8.
    Department of Endocrinology, University Hospital Galway, Newcastle, Galway, Ireland; School of Medicine, National University of Ireland Galway, Newcastle, Galway, Ireland.
    Unlabelled: Pituitary apoplexy represents an uncommon endocrine emergency with potentially life-threatening consequences. Drug-induced pituitary apoplexy is a rare but important consideration when evaluating patients with this presentation. We describe an unusual case of a patient with a known pituitary macroadenoma presenting with acute-onset third nerve palsy and headache secondary to tumour enlargement and apoplexy. Read More

    Neurological Complications of Pregnancy.
    Curr Neurol Neurosci Rep 2016 Jul;16(7):67
    SSM Healthcare-Dean Medical Group, 700 S. Park Street, Madison, WI, 53715, USA.
    Physiologic alterations during pregnancy create an environment for the occurrence of disease states that are either unique to pregnancy, occur more frequently in pregnancy, or require special management considerations that may be different from the nonpregnancy state. In the realm of cerebrovascular disease, preeclampsia, eclampsia, reversible cerebral vasoconstriction syndrome, sources of cardiogenic embolization including peripartum cardiomyopathy, cerebral venous thrombosis, pituitary apoplexy, subarachnoid hemorrhage, intracerebral hemorrhage, and special considerations for anticoagulation during pregnancy will be discussed. Management of epilepsy during pregnancy counterbalances maternal freedom from seizures against the potential for major, minor, cognitive, and behavioral fetal deformities. Read More

    Hypopituitarism in the elderly: a narrative review on clinical management of hypothalamic-pituitary-gonadal, hypothalamic-pituitary-thyroid and hypothalamic-pituitary-adrenal axes dysfunction.
    J Endocrinol Invest 2016 Oct 21;39(10):1115-24. Epub 2016 May 21.
    Department of Clinical and Experimental Medicine, Endocrinology Unit, University of Messina, AOU Policlinico "G. Martino" (Block H, Floor 4), Via Consolare Valeria, 1, 98125, Messina, Italy.
    Hypopituitarism is an uncommon and under-investigated endocrine disorder in old age since signs and symptoms are unspecific and, at least in part, can be attributed to the physiological effects of aging and related co-morbidities. Clinical presentation is often insidious being characterized by non-specific manifestations, such as weight gain, fatigue, low muscle strength, bradipsychism, hypotension or intolerance to cold. In these circumstances, hypopituitarism is a rarely life-threatening condition, but evolution may be more dramatic as a result of pituitary apoplexy, or when a serious condition of adrenal insufficiency suddenly occurs. Read More

    Pituitary apoplexy causing spontaneous remission of acromegaly following long-acting octreotide therapy: a rare drug side effect or just a coincidence.
    Oxf Med Case Reports 2016 Apr 26;2016(4):81-3. Epub 2016 Apr 26.
    Department of Endocrinology , Shri Ram Murti Smarak Institute of Medical Sciences (SRMS IMS) , Bareilly, Uttar Pradesh , India.
    Pituitary apoplexy is characterized by abrupt onset of haemorrhage or non-haemorrhagic infarction of a pituitary adenoma. The clinical features include acute onset severe headache, visual field defects, meningeal irritation, ophthalmoplegia and hypopituitarism. The pituitary apoplexy may be clinically silent in ∼25% of patients. Read More

    Isolated traumatic retroclival hematoma: case report and review of literature.
    Childs Nerv Syst 2016 Sep 27;32(9):1749-55. Epub 2016 Apr 27.
    Department of Neurosurgery, Medical College of Wisconsin and Children's Hospital of Wisconsin, 9200 West Wisconsin Ave, Milwaukee, WI, 53226, USA.
    Background: Retroclival hematomas are a rare entity. The pathology can be categorized into epidural hematoma or subdural hematoma based on the anatomy of the tectorial membrane. Frequently, the etiology is related to accidental trauma, though other mechanisms have been observed, including coagulopathy, non-accidental trauma, and pituitary apoplexy. Read More

    A Benchmark for Preservation of Normal Pituitary Function After Endoscopic Transsphenoidal Surgery for Pituitary Macroadenomas.
    World Neurosurg 2016 Jul 23;91:371-5. Epub 2016 Apr 23.
    Division of Neuroradiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
    Introduction: We report a contemporary consecutive series of 80 patients operated on for benign pituitary macroadenomas, followed endocrinologically for at least 3 months postoperatively. These patients were systematically evaluated preoperatively by high-resolution magnetic resonance imaging designed to detect the position of normal gland relative to the lesion. The rate of preservation of normal pituitary was critically analyzed using this strategy combined with endoscopic transsphenoidal resection. Read More

    Pituitary apoplexy - bespoke patient management allows good clinical outcome.
    Clin Endocrinol (Oxf) 2016 Sep 4;85(3):415-22. Epub 2016 May 4.
    Department of Endocrinology, Salford Royal NHS Foundation Trust, Salford, Greater Manchester, UK.
    Objective: To describe the clinical presentation, management and outcome of pituitary apoplexy from a single centre and retrospectively apply the Pituitary Apoplexy Score (PAS).

    Design: Retrospective review of patients presenting with classical pituitary apoplexy to a single neurosurgical centre in the Greater Manchester region.

    Results: A total of 31 cases with classical pituitary apoplexy were identified between 2005 and 2014. Read More

    An Atypical Case of Lymphocytic Panhypophysitis in a Pregnant Woman.
    J Neuroophthalmol 2016 Sep;36(3):313-6
    Department of Ophthalmology (ECD, JFR), Neuro-Ophthalmology Service, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts; Department of Ophthalmology (ECD, FAJ, AMS), David G. Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts; and Department of Ophthalmology (ECD, FAJ, AMS, JFR), Harvard Medical School, Boston, Massachusetts.
    We describe a case of lymphocytic panhypophysitis (LPH) in a 30-year-old woman presenting with throbbing headaches and vision changes during her third trimester. LPH is the rarest subclassification of lymphocytic hypophysitis; it is typically found in males and has not previously been associated with pregnancy. Anterior and posterior pituitary deficits together with headaches should raise a high degree of suspicion regarding the possibility of LPH. Read More

    Headache and Its Approach in Today's NeuroIntensive Care Unit.
    Neurocrit Care 2016 Oct;25(2):320-34
    Departments of Neurology, Neurosurgery, and Critical Care, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
    Headache is a very common symptom in the neurointensive care unit (neuroICU). While headache in the neuroICU can be caused by worsening of a pre-existing primary headache disorder, most are secondary to another condition. Additionally, headache can be the presenting symptom of a number of conditions requiring prompt recognition and treatment including subarachnoid hemorrhage, ischemic and hemorrhagic stroke, central nervous system infection, pituitary apoplexy, and cerebral vasoconstriction. Read More

    Pituitary apoplexy presenting as diabetic ketoacidosis: A great simulator?
    Neuro Endocrinol Lett 2016 ;37(1):9-11
    Pituitary apoplexy is a life-threatening illness due to acute infarction of the pituitary gland. The most common symptoms associated with pituitary apoplexy are headache, nausea, vomiting, visual impairment, hypopituitarism, and altered mental status. Diabetic ketoacidosis is a common acute complication of diabetes mellitus and is itself associated with similar symptoms. Read More

    Reasons and results of endoscopic surgery for prolactinomas: 142 surgical cases.
    Acta Neurochir (Wien) 2016 May 12;158(5):933-42. Epub 2016 Mar 12.
    Faculty of Medicine, Department of Neurosurgery, Hacettepe University, Ankara, Turkey.
    Background: We report herein a retrospective analysis of the results of 142 consecutive prolactinoma cases operated upon using an endoscopic endonasal trans-sphenoidal approach over a period of 6 years.

    Methods: Medical records of 142 cases were analysed with respect to indications for surgery, duration of hospital stay, early remission rates, failures and recurrence rates during a median follow-up of 36 months.

    Results: On the basis of magnetic resonance imaging (MRI) data, 19 patients (13. Read More

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