1,296 results match your criteria Pituitary Apoplexy


Pituitary adenoma apoplexy associated with vardenafil intake.

Acta Neurochir (Wien) 2019 Jan 12;161(1):129-131. Epub 2018 Dec 12.

Department of Neurological Surgery, Dentistry, and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.

Vardenafil is a potent phosphodiesterase-5 (PDE-5) inhibitor used in the treatment of erectile dysfunction. Several cases of stroke related to the use of PDE-5 inhibitors have been reported. Here, we describe the case of a 51-year-old man with headache and right ophthalmoplegia subsequent to vardenafil consumption. Read More

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http://dx.doi.org/10.1007/s00701-018-3763-xDOI Listing
January 2019
1 Read

[Spontaneous remission of acromegaly and Cushing's disease in older patients. Report of two cases].

Rev Med Chil 2018 Jul;146(7):933-937

Departamento de Neurología y Neurocirugía, Hospital Clínico de la Universidad de Chile, Santiago, Chile.

Pituitary diseases such as acromegaly and Cushing's disease require surgical or medical therapy. In some functioning pituitary tumors, a spontaneous remission of hormonal hypersecretion is observed, mainly associated to apoplexy or pituitary infarction. We report the evolution of two female patients older than 70 years at the time of diagnosis, with multiple comorbidities. Read More

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http://dx.doi.org/10.4067/s0034-98872018000700933DOI Listing
July 2018
6 Reads

Pituitary apoplexy.

CMAJ 2018 Dec;190(48):E1419

The Post-graduate Education Center (Yamada); Department of General Internal Medicine (Fujikawa), Mitoyo General Hospital, Kan'onji, Kagawa, Japan

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http://dx.doi.org/10.1503/cmaj.180658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258221PMC
December 2018

A Perplexing Case of Pituitary Apoplexy Masquerading as Recurrent Meningitis.

J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618811370. Epub 2018 Nov 15.

University of New Mexico Health Sciences Center, Albuquerque, NM, USA.

In this article, we present an exceptional case of pituitary apoplexy in which a patient presented with meningeal symptoms of headache, stiff neck, and nausea rather than the classical findings of ophthalmoplegia and/or vision loss. The patient has had 2 similar presentations with cerebrospinal fluid showing neutrophilic pleocytosis, as well as a computed tomography scan showing a prominent pituitary gland. On current presentation, the patient's vital signs were stable and the physical examination was remarkable for nuchal rigidity. Read More

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http://journals.sagepub.com/doi/10.1177/2324709618811370
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http://dx.doi.org/10.1177/2324709618811370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243406PMC
November 2018
8 Reads

Transsphenoidal Approaches for Microsurgical Resection of Pituitary Adenomas in Pediatric Patients.

World Neurosurg 2018 Nov 23. Epub 2018 Nov 23.

Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA. Electronic address:

Objective: Pituitary adenomas are uncommon in the pediatric population. Although medical treatment can be effective in treating prolactinomas and some growth hormone-secreting tumors, resection is indicated in the setting of pituitary apoplexy, large or giant pituitary adenomas causing mass effect or visual loss, or when medical therapy becomes ineffective or intolerable. Modern microsurgical transsphenoidal approaches are potential avenues for resection in pediatric patients. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.117DOI Listing
November 2018
1 Read

Pituitary apoplexy secondary to metastatic breast carcinoma into a gonadotroph cell adenoma of the pituitary.

Br J Neurosurg 2018 Nov 26:1-4. Epub 2018 Nov 26.

a Department of Neurosurgery , Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield , United Kingdom.

A 65 year-old lady with metastatic breast cancer presented with pituitary apoplexy. Following surgery, histopathology confirmed metastatic breast carcinoma into a gonadotroph cell adenoma of the pituitary. Tumours that metastasise to a normal pituitary gland are unusual. Read More

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http://dx.doi.org/10.1080/02688697.2018.1540766DOI Listing
November 2018
1 Read

Physiologic pituitary hyperplasia causing visual disturbance during adolescence.

J Clin Neurosci 2018 Nov 20. Epub 2018 Nov 20.

Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.

We report for the first time two cases of physiologic pituitary hyperplasia causing visual disturbance during adolescence. Case 1. A 15-year-old boy visited our department with a pituitary mass lesion on magnetic resonance imaging (MRI) associated with headache and transient bitemporal hemianopsia repeating. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.11.016DOI Listing
November 2018
7 Reads

Apoplectic Silent Crooke's Cell Adenoma with Adjacent Pseudoaneurysms: Causation or Bystander?

World Neurosurg 2018 Nov 19. Epub 2018 Nov 19.

Departments of Neurosurgery and Otorhinolaryngology, Mayo Clinic, Rochester, MN, United States of America. Electronic address:

Background: Crooke's cell adenomas (CCAs) are rare and potentially aggressive pituitary tumors that often invade the cavernous sinuses. Although clinical presentations of pituitary tumors may include the development of accompanying intracranial aneurysms, there are no documented cases of coexistent intracranial aneurysms and CCAs to date. Herein we describe an apoplectic silent CCA that presented with adjacent cavernous internal carotid artery (ICA) aneurysms. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.10.232DOI Listing
November 2018
5 Reads

Pituitary Apoplexy Producing Internal Carotid and Basilar Artery Compression: A Rare Case Report.

Asian J Neurosurg 2018 Oct-Dec;13(4):1264-1268

Department of General Surgery, Islampur Multispeciality Hospital; Islampur, Sangli, Maharashtra, India.

Pituitary apoplexy is a rare disease followed by ischemic or hemorrhagic process within the pituitary adenoma. Here, we report two cases of pituitary apoplexy with a history of sudden onset of headache, vomiting, and diminished vision. Our aim is to share our experience and discuss these cases as follows: the first one to know the compression of basilar artery along with the compression of basilar part of pons and in both the cases with compression of an internal carotid artery leading to cerebral infarcts. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_90_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208222PMC
November 2018
8 Reads

Spontaneous preoperative pituitary adenoma resolution following apoplexy: a case presentation and literature review.

Br J Neurosurg 2018 Nov 19:1-6. Epub 2018 Nov 19.

a Department of Neurological Surgery , University of Miami Miller School of Medicine , Miami , FL , USA.

Purpose: We aim to more fully understand the incidence and natural history of spontaneously resolving non-functioning pituitary adenomas (NFPAs).

Methods: We report a case of spontaneous complete resolution of a NFPA revealed by preoperative magnetic resonance imaging. In addition, we searched all major databases and neurosurgery journals to perform a comprehensive literature review of all previously reported cases of spontaneously resolving NFPAs. Read More

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http://dx.doi.org/10.1080/02688697.2018.1529737DOI Listing
November 2018
1 Read

Coagulative necrotic pituitary adenoma apoplexy: A retrospective study of 21 cases from a large pituitary center in China.

Pituitary 2018 Nov 2. Epub 2018 Nov 2.

Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing, 100730, People's Republic of China.

Purpose: Coagulative necrotic pituitary apoplexy (CNPA) is a clinical entity with unique intraoperative and histopathological manifestations. We aimed to improve the knowledge of this rare disease through the largest case series published to date.

Methods: A retrospective review of 21 CNPA patients was performed from among 5095 patients who underwent surgery for pituitary adenomas at a single institution between January 2009 and June 2017. Read More

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http://link.springer.com/10.1007/s11102-018-0922-2
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http://dx.doi.org/10.1007/s11102-018-0922-2DOI Listing
November 2018
6 Reads

[Oculomotor nerve compression on MRI in a 56-year-old man with pituitary apoplexy due to panhypophisitis].

Rinsho Shinkeigaku 2018 Nov 27;58(11):668-672. Epub 2018 Oct 27.

Department of Neurology, Dokkyo Medical University.

A 56-year-old man noted sudden onset of headache, fever, right pupil-spared oculomotor nerve palsy and consciousness disturbance. Swelling of pituitary with T high intensity on brain MRI suggested the diagnosis of pituitary apoplexy. Considering significant decrease of pituitary anterior lobe hormone and central diabetes insipidus, high dose of hydrocortisone was administered. Read More

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http://dx.doi.org/10.5692/clinicalneurol.cn-001192DOI Listing
November 2018
2 Reads

Cancer immunotherapy-associated hypophysitis.

Semin Oncol 2018 Jun 21;45(3):181-186. Epub 2018 Oct 21.

Department of Radiology, University Hospital of Cagliari, Cagliari, Italy. Electronic address:

Side effects of immune checkpoint blockade are often said to be infrequent and usually mild. The uniqueness of endocrine immune-related adverse events is their non-reversibility, with incidence and prevalence destined to increase in the coming years, particularly if immunotherapy is used at earlier stages of neoplastic disease. Immune-related hypophysitis is one of these observed endocrine adverse events. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00937754183010
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http://dx.doi.org/10.1053/j.seminoncol.2018.09.002DOI Listing
June 2018
4 Reads

Conservative treatment cures an elderly pituitary apoplexy patient with oculomotor paralysis and optic nerve compression: a case report and systematic review of the literature.

Clin Interv Aging 2018 12;13:1981-1985. Epub 2018 Oct 12.

Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China,

Background: Whether conservative treatment or surgical management is the most appropriate treatment for pituitary apoplexy (PA) is controversial. In general, if severe symptoms of compression occur, such as oculomotor nerve palsy, neurosurgery is performed to relieve the compression of anatomical structures near the PA.

Case Description: We describe the case of a 79-year-old man who was found to have an intrasellar pituitary incidentaloma. Read More

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https://www.dovepress.com/conservative-treatment-cures-an-el
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http://dx.doi.org/10.2147/CIA.S181109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188166PMC
December 2018
7 Reads

Thunderclap headache: an update.

Expert Rev Neurother 2018 Dec 29;18(12):915-924. Epub 2018 Oct 29.

b Faculty of Medicine , National Yang-Ming University School of Medicine , Taipei , Taiwan.

Introduction: Thunderclap headache (TCH) is an excruciating headache that reaches maximal intensity within a minute. It has numerous potential etiologies, the most concerning of which is subarachnoid hemorrhage (SAH) due to high morbidity and mortality. Thus, patients with TCH must be evaluated urgently to identify the underlying cause and initiate prompt therapy. Read More

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https://www.tandfonline.com/doi/full/10.1080/14737175.2018.1
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http://dx.doi.org/10.1080/14737175.2018.1537782DOI Listing
December 2018
8 Reads

Bilateral Optic Tract Hyperintensity due to Pituitary Apoplexy.

Intern Med 2018 Oct 17. Epub 2018 Oct 17.

Department of Neurology and Neurological Sciences, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Japan.

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http://dx.doi.org/10.2169/internalmedicine.1515-18DOI Listing
October 2018
0.970 Impact Factor

Pituitary Adenoma Apoplexy of the Orbit, Diagnosis, and Management With Presurgical Embolization.

Ophthalmic Plast Reconstr Surg 2018 Nov/Dec;34(6):e196-e197

Johns Hopkins University School of Medicine, Wilmer Eye Institute, Baltimore, Maryland, U.S.A.

Orbital invasion of pituitary adenomas has been previously reported. In this report, the authors describe a 71-year-old female with a prolactinoma that presented with invasion of and apoplexy within the orbit. The patient underwent exenteration, followed by rapid tumor recurrence and growth. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001241DOI Listing
October 2018
1 Read

Hemorrhagic Atypical Planum Sphenoidale Meningioma with Intermittent Vision Loss-Rare Presentation of Apoplexy.

World Neurosurg 2019 Jan 4;121:71-76. Epub 2018 Oct 4.

Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA. Electronic address:

Background: Symptoms that mimic pituitary apoplexy may be encountered with other neoplastic or infectious lesions.

Case Description: This 38-year-old man presented with severe sudden-onset headache and relapsing and remitting vision loss. Radiographic imaging studies demonstrated radiographic features of a hyperdense, hemorrhagic mass in the sellar region. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183225
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http://dx.doi.org/10.1016/j.wneu.2018.09.200DOI Listing
January 2019
2 Reads

Pituitary Apoplexy Following Endoscopic Retrograde Cholangiopancreatography.

World Neurosurg 2019 Jan 4;121:201-204. Epub 2018 Oct 4.

Department of Neurological Surgery, Rutgers-New Jersey Medical School, Newark, New Jersey, USA; Department of Otolaryngology, Head and Neck Surgery, Rutgers-New Jersey Medical School, Newark, New Jersey, USA. Electronic address:

Background: Pituitary apoplexy is an uncommon neurosurgical emergency that may be the initial presentation of undiagnosed pituitary adenomas. Though the exact pathogenesis is unclear, there appears to be an association between pituitary apoplexy and medical interventions that disturb the blood supply and venous drainage of the abnormal sellar region. We present the first case of pituitary apoplexy occurring after an endoscopic retrograde cholangiopancreatography (ERCP). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183223
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http://dx.doi.org/10.1016/j.wneu.2018.09.183DOI Listing
January 2019
2 Reads

VISUAL VIGNETTE.

Endocr Pract 2018 Oct 5. Epub 2018 Oct 5.

From: 1Division of Endocrinology and Metabolism; Department of Medicine; University of Virginia School of Medicine; Charlottesville, VA.

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http://dx.doi.org/10.4158/EP-2018-0439DOI Listing
October 2018
1 Read

Pituitary Adenoma Apoplexy: Review of Personal Series.

Asian J Neurosurg 2018 Jul-Sep;13(3):560-564

Division of Neurosurgery, Ospedali Riuniti di Ancona, Italy.

Background: Pituitary apoplexy is a life-threatening event with unspecific clinical background and no standardized treatment.

Materials And Methods: The authors retrospectively analyzed seventeen patients affected by pituitary adenoma apoplexy and treated in a 10-year period. Thirteen patients underwent surgery through transsphenoidal route while four patients have been treated conservatively. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_344_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159099PMC
October 2018
3 Reads

Varicella causing remission of Cushing's disease.

BMJ Case Rep 2018 Sep 23;2018. Epub 2018 Sep 23.

Department of Internal Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

An 18-year-old male with Cushing's disease presented with generalised skin eruptions and backache. He was diagnosed with varicella infection. During the course of the illness, he developed persistent vomiting. Read More

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http://dx.doi.org/10.1136/bcr-2018-225867DOI Listing
September 2018
4 Reads

Developing an optimal follow-up strategy based on the natural history of nonfunctioning pituitary adenomas.

J Neurosurg 2018 Sep 1:1-7. Epub 2018 Sep 1.

1Department of Internal Medicine.

OBJECTIVEThe natural history and proper algorithm for follow-up testing of nonfunctioning pituitary adenomas (PAs) are not well known, despite their relatively high prevalence. The aim of this study was to suggest the optimal follow-up algorithm for nonfunctioning PAs based on their natural history.METHODSThe authors followed up 197 patients with nonfunctioning PAs that had not been treated (including surgery and radiation therapy) at the time of detection, in a single center, between March 2000 and February 2017. Read More

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http://dx.doi.org/10.3171/2018.4.JNS172148DOI Listing
September 2018
6 Reads
3.740 Impact Factor

Post-Traumatic Pituitary Tumor Apoplexy After Closed Head Injury: Case Report and Review of the Literature.

World Neurosurg 2018 Dec 10;120:331-335. Epub 2018 Sep 10.

Department of Neurological Surgery, Rutgers-New Jersey Medical School, Newark, New Jersey, USA; Department of Otolaryngology-Head and Neck Surgery, Rutgers-New Jersey Medical School, Newark, New Jersey, USA. Electronic address:

Background: Head trauma is a rare inciting factor of pituitary apoplexy (PA); however, there is a clear temporal relationship between trauma and apoplexy, and this is the first reported case of PA after an assault.

Case Description: We present a rare case of a 63-year-old man who developed PA after sustaining a closed head injury from assault with a metal pole. The patient had a known pituitary tumor for which he had previously declined surgical resection. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.08.238DOI Listing
December 2018
1 Read

Pituitary Apoplexy in Long-Term Cabergoline User During Thrombocytopenia Due to Chemotherapy for Chronic Myelocytic Leukemia.

World Neurosurg 2018 Dec 3;120:290-295. Epub 2018 Sep 3.

Department of Neurosurgery, Kurashiki Central Hospital, Okayama, Japan.

Background: Pituitary apoplexy (PA) is a life-threatening syndrome. The usage of a dopamine agonist, such as bromocriptine or cabergoline, is considered a predisposing factor for PA, which commonly occurs 1.5 years within commencement. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.08.187DOI Listing
December 2018
4 Reads

An unsuspected complication with immune checkpoint blockade: a case report.

J Med Case Rep 2018 Sep 4;12(1):246. Epub 2018 Sep 4.

Internal Medicine Department, Hospital Universitario 12 de Octubre, Madrid, Spain.

Background: Immunotherapy treatment with immune-checkpoint blockade has become a new paradigm in cancer treatment. Despite its efficacy, it has also given rise to a new class of adverse events, immune-related adverse events, which may affect any organ, including the thyroid and the pituitary.

Case Presentation: We present a case of a 77-year-old Caucasian man with metastatic renal cell carcinoma on immunotherapy treatment who was admitted to our hospital with a severe persistent headache of sudden onset. Read More

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http://dx.doi.org/10.1186/s13256-018-1782-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122676PMC
September 2018
2 Reads

Pituitary apoplexy after regadenoson myocardial perfusion scan.

J Nucl Cardiol 2018 Aug 30. Epub 2018 Aug 30.

Cardiology, University of Iowa Hospital and Clinics, Iowa City, USA.

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http://dx.doi.org/10.1007/s12350-018-1428-zDOI Listing

Clinical and biochemical characteristics of patients presenting with pituitary apoplexy.

Endocr Connect 2018 08 23. Epub 2018 Aug 23.

N Martin, Imperial College Healthcare NHS Trust, London, United Kingdom of Great Britain and Northern Ireland

Purpose: To review the clinical and biochemical characteristics and clinical outcome of patients presenting with pituitary apoplexy to a tertiary centre.

Methods: We retrospectively reviewed the clinical features, predisposing factors, biochemistry and clinical outcome of patients presenting with pituitary apoplexy to Imperial College Healthcare NHS Trust between 1991 to 2015.

Results: We identified 64 patients with pituitary apoplexy (more complete clinical records were available in 52 patients). Read More

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http://dx.doi.org/10.1530/EC-18-0255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198188PMC
August 2018
12 Reads

Prolactin-Secreting Lung Adenocarcinoma Metastatic to the Pituitary Mimicking a Prolactinoma: A Case Report.

Neurosurgery 2018 Aug 20. Epub 2018 Aug 20.

Department of Neurosurgery, Center of Pituitary Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background And Importance: Metastasis to the pituitary gland is uncommon in patients with systemic disseminated cancer. Individual articles have reported cases of pituitary metastasis mimicking a prolactinoma, but no case of a prolactin-secreting tumor metastasizing to the pituitary mimicking a prolactinoma has been reported so far.

Clinical Presentation: This article reports a 67-yr-old man with a recent onset of headaches, ophthalmoplegia, hypopituitarism, and hyperprolactinemia who was initially diagnosed with prolactinoma and given bromocriptine in the local hospital. Read More

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http://dx.doi.org/10.1093/neuros/nyy386DOI Listing
August 2018
4 Reads

[Surgical Planning for a Giant Pituitary Adenoma Based on Evaluation of the Fine Feeding System and Angioarchitecture:A Case Report].

No Shinkei Geka 2018 Aug;46(8):691-697

Department of Neurosurgery, Kohnan Hospital.

Giant pituitary adenomas carry higher surgical risks despite recent advances in microsurgical and/or endoscopic surgery. In particular, postoperative acute catastrophic changes without major vessel disturbance are still extremely difficult to predict, and may manifest as postoperative pituitary apoplexy with very poor outcomes. These changes are associated with injuries to the capillary intratumoral feeders and/or drainers, which frequently have diameters of less than 300µm, and result in drastic hemodynamic changes. Read More

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http://dx.doi.org/10.11477/mf.1436203795DOI Listing

Clinically Silent Adrenocorticotropic Hormone-Positive Crooke Cell Adenoma: Case Report and Review of Literature.

World Neurosurg 2018 Nov 2;119:197-200. Epub 2018 Aug 2.

Department of Neurosurgery, The Medical College of Georgia at Augusta University, Augusta, Georgia, USA. Electronic address:

Background: Pituitary adenomas are one of the most common tumors of adulthood; however, subtypes such as Crooke cell adenoma are relatively rare.

Case Description: We present the case of a 55-year-old woman who presented with new-onset intermittent headache and dizziness. Clinical and laboratory investigations were not suggestive of corticotroph tumor. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.07.233DOI Listing
November 2018
4 Reads

Unilateral Tuberothalamic Artery Ischemia Caused by Pituitary Apoplexy.

J Neurol Surg A Cent Eur Neurosurg 2018 Nov 20;79(6):550-554. Epub 2018 Jul 20.

Department of Neurosurgery, Helios Klinikum Erfurt, Erfurt, Germany.

Background And Importance:  Pituitary apoplexy (PA) occasionally occurs in patients with pituitary adenoma and may cause severe functional deficits. Headache, pituitary insufficiency, visual impairment, and cranial nerve palsies are the most frequent symptoms in patients with PA. Secondary cerebral ischemia develops in only a limited number of PA patients. Read More

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http://dx.doi.org/10.1055/s-0038-1656514DOI Listing
November 2018
13 Reads

Pituitary tumour apoplexy within prolactinomas in children: a more aggressive condition?

Pituitary 2018 Oct;21(5):474-479

Departments of Paediatric Neurosurgery, Sheffield Children's Hospital, Sheffield, S10 2TF, UK.

Objectives: To evaluate clinical presentations, diagnosis and management of paediatric patients presenting with pituitary apoplexy.

Methods: A retrospective case series describing a cohort of paediatric patients presenting with this condition from 2010-2016 to a tertiary referral children's hospital in the United Kingdom.

Results: Pituitary apoplexy is a rare condition that seems to have a higher relative incidence in children than adults. Read More

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http://dx.doi.org/10.1007/s11102-018-0900-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132972PMC
October 2018
2 Reads

Cystic Lymphocytic Hypophysitis Mimicking Pituitary Apoplexy: Daunting Challenge.

World Neurosurg 2018 Oct 6;118:1-4. Epub 2018 Jul 6.

Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan.

Background: Inflammatory lesions of the pituitary gland including hypophysitis are poorly understood, and it is difficult to make a correct diagnosis on the basis of only clinical and radiologic findings.

Case Description: An otherwise healthy 68-year-old man presented with sudden onset of headache, visual impairment, and pituitary insufficiency. Magnetic resonance imaging revealed a pituitary mass with cystic component showing changing intensity on follow-up images. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.06.230DOI Listing
October 2018
1 Read

Pituitary Apoplexy With Bilateral Oculomotor Nerve Palsy.

Neurohospitalist 2018 Jul 7;8(3):NP4-NP5. Epub 2018 May 7.

Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1177/1941874418773923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022899PMC
July 2018
2 Reads

Headaches in Patients with Pituitary Tumors: a Clinical Conundrum.

Curr Pain Headache Rep 2018 Jul 4;22(8):57. Epub 2018 Jul 4.

The Neurological Institute of New York, 710 West 168th St, New York, NY, 10032, USA.

Purpose Of Review: Pituitary tumors account for approximately 17% of all intracranial neoplasms, with the majority being pituitary adenomas. Often, these are found incidentally during a workup for headache; however, the relationship between symptom and pathology remains unclear. The purpose of this article is to review the most recent literature on the epidemiology, pathophysiology, and management of headaches in patients with pituitary tumors. Read More

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http://dx.doi.org/10.1007/s11916-018-0709-1DOI Listing
July 2018
18 Reads

Neuro-Endocrine Recovery After Pituitary Apoplexy: Prolactin as a Predictive Factor.

Exp Clin Endocrinol Diabetes 2018 Jul 2. Epub 2018 Jul 2.

Department of Neurosurgery, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.

Objective: Pituitary apoplexy is a serious medical complication of a pre-existing pituitary adenoma characterized by a variety of clinical symptoms ranging from mild headache to neurologically impaired and finally comatose patients. Management options are surgery or conservative treatment (e. g. Read More

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http://dx.doi.org/10.1055/a-0640-2915DOI Listing
July 2018
24 Reads

An exceptional presentation of pituicytoma apoplexy: A case report.

Oncol Lett 2018 Jul 3;16(1):643-647. Epub 2018 May 3.

Department of Neurosurgery, University Hospital of Lausanne, 1011 Lausanne, Switzerland.

Pituicytomas are a rare form of indolent neoplasms, which typically present with visual disturbance and hypopituitarism. Complete resection by a trans-sphenoidal approach is the optimal treatment. Only 80 cases have been described thus far in the current literature and the present case is the first to describe the development of pituitary apoplexy in the context of a pituicytoma. Read More

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http://dx.doi.org/10.3892/ol.2018.8625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006376PMC
July 2018
23 Reads
0.990 Impact Factor

Evaluation of the Effect of Age, Gender, and Skeletal Class on the Dimensions of Sella Turcica Using Lateral Cephalogram.

Contemp Clin Dent 2018 Apr-Jun;9(2):195-199

Department of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal University, Manipal, Karnataka, India.

Context: Sella turcica or pituitary fossa is a saddle-shaped concavity housing the pituitary gland and seen clearly on lateral cephalogram. This makes it a good source of additional diagnostic information related to pathology of the pituitary gland or to various syndromes that affect the craniofacial region.

Aims: The aim of this retrospective study was to determine the average dimensions and morphological variations of the sella turcica in different age groups and to evaluate any difference in size between males and females in the study population. Read More

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http://dx.doi.org/10.4103/ccd.ccd_805_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968682PMC

Myasthenia gravis imitating pituitary apoplexy in macroprolactinoma.

Hormones (Athens) 2018 Sep 2;17(3):423-426. Epub 2018 Jun 2.

Center for the Diagnosis and Treatment of Hypothalamic-Pituitary Disorders (Pituitary Unit), IRCCS Institute of Neurological Sciences of Bologna, Via Altura, 3, 40141, Bologna, Italy.

Myasthenia gravis (MG) is an autoimmune disease affecting neuromuscular transmission that manifests with muscle weakness and typically involves the eye muscles, often producing diplopia and ptosis. Recent studies suggest that hyperprolactinaemia may have a role in the development of MG, although its association with prolactinoma is extremely rare. We report the unusual case of a 71-year-old male affected with macroprolactinoma, who presented at our Center 2 weeks after starting cabergoline treatment because of acute onset of headache, diplopia, and ptosis. Read More

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http://dx.doi.org/10.1007/s42000-018-0036-2DOI Listing
September 2018
2 Reads

The Predictive Value of Suprasellar Extension for Visual Function Evaluation in Chinese Patients with Nonfunctioning Pituitary Adenoma with Optic Chiasm Compression.

World Neurosurg 2018 Aug 29;116:e960-e967. Epub 2018 May 29.

Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Objective: To analyze the quantitative relationship between suprasellar extension (SSE) and visual function impairment in Chinese patients with nonfunctioning pituitary adenoma (NFPA) with optic chiasm compression.

Methods: We retrospectively reviewed 117 patients with NFPA and optic chiasm compression treated at our hospital between January 2013 and December 2016. The quantitative relationships between SSE detected on sagittal and coronal magnetic resonance imaging (MRI) sections and visual function, including visual acuity (VA) and visual fields (VFs), were analyzed. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.05.141DOI Listing
August 2018
3 Reads

Pituitary Apoplexy Presenting as Ophthalmoplegia and Altered Level of Consciousness without Headache.

Case Rep Endocrinol 2018 9;2018:7124364. Epub 2018 May 9.

Division of Endocrinology, Department of Medicine, Riverside University Health System Medical Center, Moreno Valley, CA, USA.

Pituitary apoplexy (PA) is a clinical syndrome caused by acute ischemic infarction or hemorrhage of the pituitary gland. The typical clinical presentation of PA includes acute onset of severe headache, visual disturbance, cranial nerve palsy, and altered level of consciousness. . Read More

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http://dx.doi.org/10.1155/2018/7124364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966706PMC
May 2018
3 Reads

Pituitary Abscess: A Rare Clinical Entity in the Presence of Acute Rhinosinusitis: A Case Report.

J Neurol Surg Rep 2018 Apr 25;79(2):e36-e40. Epub 2018 May 25.

Department of Surgery - Otolaryngology Head & Neck Surgery, University of Florida College of Medicine - Jacksonville, Jacksonville, Florida, United States.

A pituitary abscess is an often-overlooked diagnosis in the clinical presentation of a sellar mass. Due to its rare incidence and nonspecific presentation, diagnosis and treatment is often delayed. The authors describe a 56-year-old male patient presenting with acute onset of severe headache, visual field deficit, and radiologic findings of an expansile sellar lesion. Read More

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http://dx.doi.org/10.1055/s-0038-1656531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969996PMC
April 2018
2 Reads

Pituitary apoplexy following lumbar fusion surgery in prone position: A case report.

Medicine (Baltimore) 2018 May;97(19):e0676

Department of Anesthesia and Pain Medicine, Incheon St. Mary's hospital, College of Medicine, The Catholic University of Korea, Incheon, Republic of Korea.

Rationale: Pituitary apoplexy (PA) is a syndrome caused by acute hemorrhage or infarction of the pituitary gland, generally within a pituitary adenoma. PA following spinal surgery is a very rare complication and may be difficult to diagnose. However, early diagnosis of PA is essential for the timely treatment of pan-hypopituitarism and prevention of severe neurologic complications. Read More

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http://dx.doi.org/10.1097/MD.0000000000010676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959393PMC
May 2018
2 Reads

Extensive Pituitary Apoplexy after Chemotherapy in a Patient with Metastatic Breast Cancer.

Brain Tumor Res Treat 2018 Apr;6(1):43-46

Department of Cancer Control, National Cancer Center, Graduate School of Cancer Science and Policy, Goyang, Korea.

Surgery, anticoagulation therapy, pregnancy, and hormone treatments, such as bromocriptine, are well-characterized precipitating factors for pituitary apoplexy. However, whether cytotoxic chemotherapy for systemic cancer could cause pituitary apoplexy has not been investigated. Here, we present a case of a 41-year-old woman who developed a severe headache with decreased visual acuity after intravenous cytotoxic chemotherapy to treat metastatic breast cancer. Read More

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http://dx.doi.org/10.14791/btrt.2018.6.e7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932299PMC
April 2018
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The Outcomes of Pituitary Apoplexy with Conservative Treatment: Experiences at a Single Institution.

World Neurosurg 2018 Jul 27;115:e703-e710. Epub 2018 Apr 27.

Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

Objective: Pituitary apoplexy is an unpredictable complication caused by hemorrhage or infarction in a pituitary adenoma. We retrospectively analyzed the radiologic and clinical outcomes of patients with conservatively managed pituitary apoplexy.

Methods: A total of 32 patients who had undergone conservative treatment with high-dose corticosteroid replacement were enrolled in this study. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.04.139DOI Listing
July 2018
2 Reads

Clinical and imaging features of pituitary apoplexy and role of imaging in differentiation of clinical mimics.

Quant Imaging Med Surg 2018 Mar;8(2):219-231

Department of Radiology, SUNY Upstate Medical University, Syracuse, NY, USA.

To discuss the clinical syndrome, review common imaging findings of pituitary apoplexy (PA) and role of imaging in therapy and follow-up. Also, to review other acute clinical scenarios with similar clinical and/or imaging findings as PA. PA is a severe and potentially life-threatening medical emergency, characterized by constellation of symptoms/signs that occur as a result of acute hemorrhage and/or infarction in pituitary gland. Read More

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http://qims.amegroups.com/article/view/18852/18950
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http://dx.doi.org/10.21037/qims.2018.03.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891682PMC
March 2018
4 Reads

Management of cystic prolactinomas: a review.

Pituitary 2018 Aug;21(4):425-430

Institute of Endocrinology, Diabetes and Metabolism, Rambam Health Care Campus, HaAliya HaShniya Street 8, 3109601, Haifa, Israel.

Introduction: Cystic prolactinoma is a variant of prolactin-secreting pituitary adenoma. The strategies for the management of cystic prolactinoma have not been addressed thoroughly in clinical guidelines.

Methods: A literature search was performed using Pubmed to review the current approaches to the treatment of cystic prolactinoma. Read More

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http://dx.doi.org/10.1007/s11102-018-0888-0DOI Listing
August 2018
6 Reads

Landscape of Molecular Events in Pituitary Apoplexy.

Front Endocrinol (Lausanne) 2018 20;9:107. Epub 2018 Mar 20.

Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Apoplectic pituitary adenomas cause significant morbidity and even mortality. The pituitary apoplexy denotes a pituitary adenoma presenting with hemorrhage and/or infarction, implementation in remedial effects of various of drugs in pituitary apoplexy is a promising pharmacogenomic field in the near future adenoma treatment. Indisputably, this is an important horizon for complicated pituitary adenomas. Read More

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http://dx.doi.org/10.3389/fendo.2018.00107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869273PMC